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1. Heparin Mimic Material Derived from Cellulose Nanocrystals

Author:
Gallagher, Zahra J.; Fleetwood, Sara; Kirley, Terence L.; Shaw, Maureen A.; Mullins, Eric S.; Ayres, Neil; Foster, E. Johan
Source:
Biomacromolecules 2020 v.21 no.3 pp. 1103-1111
ISSN:
1526-4602
Subject:
blood coagulation; coagulation,   etc   ; anticoagulants; blood; cellulose; heparin; long term effects; mechanical properties; moieties; nanocrystals;     Show all 10 Subjects
Abstract:
... This study analyzes and evaluates the use of cellulose nanocrystals (CNCs), stiff nanosized natural materials that have been modified to mimic heparin. These CNCs are simple polysaccharides with a similar backbone structure to heparin, which when modified reduces coagulation and potentially the long-term effects of solution-based anticoagulants. Thus, CNCs represent an ideal foundation for generat ...
DOI:
10.1021/acs.biomac.9b01460

2. Total Synthesis of Clavatadine B

Author:
Davenport, Michael T.; Dickson, Jordan A.; Johnson, Matthew R.; Chamberland, Stephen
Source:
Journal of natural products 2019 v.82 no.11 pp. 3191-3195
ISSN:
1520-6025
Subject:
blood coagulation,   etc   ; humans; lactones;     Show all 3 Subjects
Abstract:
... The first total synthesis of clavatadine B (2), a natural product found to be a selective human blood coagulation factor XIa inhibitor, is described. A convergent approach that exemplifies the advantages of direct, early stage guanidinylation provided an immediate clavatadine B precursor, which was assembled in an efficient manner using known synthetic precursors of the structurally related natura ...
DOI:
10.1021/acs.jnatprod.9b00813

3. Monte Carlo Aggregation Code (MCAC) Part 2: Application to soot agglomeration, highlighting the importance of primary particles

Author:
Morán, J.; Yon, J.; Poux, A.; Corbin, F.; Ouf, F.-X.; Siméon, A.
Source:
Journal of colloid and interface science 2020 v.575 pp. 274-285
ISSN:
0021-9797
Subject:
coagulation,   etc   ; fractal dimensions; mathematical models; nanoparticles; soot; temporal variation;     Show all 6 Subjects
Abstract:
... During the agglomeration of nanoparticles and in particular, soot, a change in both the flow regime (from free molecular to near continuum) as well as the change of agglomeration regime (from ballistic to diffusive) is expected. However, these effects are rarely taken into account in numerical simulations of particle agglomeration and yet, they are suspected to have an important impact on the aggl ...
DOI:
10.1016/j.jcis.2020.04.085

4. Arsenic release: Insights into appropriate disposal of arsenic-loaded algae precipitated from arsenic contaminated water

Author:
Wang, Zhenhong; Gui, Herong; Luo, Zhuanxi; Sarakiotia, Ioannis L.; Yan, Changzhou; Laing, Gijs Du
Source:
Journal of hazardous materials 2020 v.384 pp. 121249
ISSN:
0304-3894
Subject:
coagulation,   etc   ; algae; arsenic; arsenites; heat treatment; models; risk; water pollution;     Show all 8 Subjects
Abstract:
... Limited information is available on arsenic (As) release from As-loaded algae precipitated from As contaminated water and its subsequently appropriate disposal. In this study, selected M. aeruginosa as algal model, changes of As concentrations and its speciation were thus investigated in the in-situ treated algae water by optimal coagulation. Meanwhile, after ex-situ disposal, As release kinetics ...
DOI:
10.1016/j.jhazmat.2019.121249

5. Temperature responsive self-assembled hydroxybutyl chitosan nanohydrogel based on homogeneous reaction for smart window

Author:
Bi, Shichao; Feng, Chao; Wang, Mengyang; Kong, Ming; Liu, Ya; Cheng, Xiaojie; Wang, Xuanpeng; Chen, Xiguang
Source:
Carbohydrate polymers 2020 v.229 pp. 115557
ISSN:
0144-8617
Subject:
coagulation,   etc   ; biodegradability; chitosan; light; phase transition; potassium hydroxide; temperature; urea;     Show all 8 Subjects
Abstract:
... Chitosan (CS) based self-assembled nanohydrogels are considered as promising platform for biomedicine, petrochemical, agricultural and food applications due to their unique biodegradability, nano-interface effect, and intelligent responsiveness. However, the most CS derivatives are prepared in heterogeneous system, which is unstable and environmentally unfriendly. In this work, a series of hydroxy ...
DOI:
10.1016/j.carbpol.2019.115557

6. Coagulation effect of aero submicron particles on plant leaves: Measuring methods and potential mechanisms

Author:
Yin, Shan; Lyu, Junyao; Zhang, Xuyi; Han, Yujie; Zhu, Yanhua; Sun, Ningxiao; Sun, Wen; Liu, Chunjiang
Source:
Environmental pollution 2020 v.257 pp. 113611
ISSN:
0269-7491
Subject:
coagulation,   etc   ; air pollution; dry deposition; human health; particle size; particulates;     Show all 6 Subjects
Abstract:
... Aero submicron particles (d < 1 μm) have attracted widely attention due to their difficulty in removal from the air and serious threat to human health. Leaves are considered as important organs to purify particulate matter and alleviate air pollution. However, the current research mainly focuses on the removal capacity of particulate matter by urban plants at different scales, there are relatively ...
DOI:
10.1016/j.envpol.2019.113611

7. Novel Pheretima guillelmi-derived antithrombotic protein DPf3: Identification, characterization, in vitro evaluation and antithrombotic mechanisms investigation

Author:
Wu, Yali; Hu, Shaonan; Ma, Yunnan; Zhao, Bo; Yang, Wanqing; Lu, Yang; Li, Pengyue; Du, Shouying
Source:
International journal of biological macromolecules 2020 v.154 pp. 545-556
ISSN:
0141-8130
Subject:
blood coagulation; coagulation,   etc   ; Pheretima; amino acid sequences; amino acids; anticoagulants; databases; fibrin; fibrinogen; in vitro studies; ion exchange chromatography; plasminogen;     Show all 12 Subjects
Abstract:
... In this study, the antithrombotic protein, named DPf3, was purified from Pheretima guillelmi by ion-exchange chromatography. The protein pattern of DPf3 was mainly at 26–34 kDa; its two main proteins, DPf3 ID NO.1 and NO.2, were detected to be 36,121.745 Da and 24,485.004 Da consisting of 329 and 241 amino acids, respectively; the full covered protein sequences were consistent with Ac44553_g1_i1_1 ...
DOI:
10.1016/j.ijbiomac.2020.03.097

8. Aptamer-antibody dual probes on single-walled carbon nanotube bridged dielectrode: Comparative analysis on human blood clotting factor

Author:
Yao, Jian; Li, Shujing; Zhang, Liping; Yang, Yuzhi; Gopinath, Subash C.B.; Lakshmipriya, Thangavel; Zhou, Yawei
Source:
International journal of biological macromolecules 2020 v.151 pp. 1133-1138
ISSN:
0141-8130
Subject:
blood coagulation; blood coagulation factors,   etc   ; antibodies; arthritis; blood serum; carbon nanotubes; detection limit; electrodes; hemophilia; hemorrhage; humans; oligonucleotides; pain; surgery;     Show all 14 Subjects
Abstract:
... Haemophilia is a blood clotting disorder known as ‘Christmas disease’ caused when the blood has defect with the clotting factor(s). Bleeding leads various issues, such as chronic pain, arthritis and a serious complication during the surgery. Identifying this disease is mandatory to take the necessary treatment and maintains the normal clotting. It has been proved that the level of factor IX (FIX) ...
DOI:
10.1016/j.ijbiomac.2019.10.156

9. Optimized coagulation pathway of Al13: Effect of in-situ Aggregation of Al13

Author:
Wang, Pin; Jiao, Ruyuan; Liu, Libing; Xiao, Feng; An, Guangyu; Wang, Dongsheng
Source:
Chemosphere 2019 v.230 pp. 76-83
ISSN:
0045-6535
Subject:
coagulation,   etc   ; aluminum; neutralization; pH; silica;     Show all 5 Subjects
Abstract:
... The coagulation mechanism for removing particles by Al13 has been extensively investigated for water treatments. It was widely accepted that Al13 played important roles in coagulation mainly by charge neutralization and electrostatic patch. However, the discovery of Al13 aggregates (Al13agg) in flocs indicated that the real coagulation process should be different from the previous understanding, i ...
DOI:
10.1016/j.chemosphere.2019.05.053

10. Resistance of South American opossums to vWF-binding venom C-type lectins

Author:
Drabeck, Danielle H.; Rucavado, Alexandra; Hingst-Zaher, Erika; Cruz, Yolanda P.; Dean, Antony M.; Jansa, Sharon A.
Source:
Toxicon 2020 v.178 pp. 92-99
ISSN:
0041-0101
Subject:
blood coagulation; blood coagulation factors,   etc   ; Didelphis virginiana; Monodelphis domestica; Viperidae; amino acids; blood plasma; blood platelets; evolutionary adaptation; lectins; metalloproteinases; opossums; phospholipases; platelet aggregation; snake venoms;     Show all 15 Subjects
Abstract:
... Opossums in the clade Didelphini are well known to be resistant to snake venom due to endogenous circulating inhibitors which target metalloproteinases and phospholipases. However, the mechanisms through which these opossums cope with a variety of other damaging venom proteins are unknown. A protein involved in blood clotting (von Willebrand Factor) has been found to have undergone rapid adaptive ...
DOI:
10.1016/j.toxicon.2020.02.024

11. Dirofilaria immitis possesses molecules with anticoagulant properties in its excretory/secretory antigens

Author:
Diosdado, Alicia; Simón, Fernando; Morchón, Rodrigo; González-Miguel, Javier
Source:
Parasitology 2020 v.147 no.5 pp. 559-565
ISSN:
1469-8161
Subject:
blood coagulation; coagulation,   etc   ; Brugia malayi; Dirofilaria immitis; adults; anticoagulant activity; antigens; blood platelets; fibrin; habitats; hosts; mammals; mass spectrometry; polyacrylamide gel electrophoresis; sodium dodecyl sulfate; thrombosis;     Show all 16 Subjects
Abstract:
... Dirofilaria immitis is a parasitic nematode that survives in the circulatory system of suitable hosts for many years, causing the most severe thromboembolisms when simultaneous death of adult worms occurs. The two main mechanisms responsible for thrombus formation in mammals are the activation and aggregation of platelets and the generation of fibrin through the coagulation cascade. The aim of thi ...
DOI:
10.1017/S0031182020000104

12. Induction heating by magnetic microbeads for pasteurization of liquid whole eggs

Author:
Wang, Gaoshang; Wan, Zhili; Yang, Xiaoquan
Source:
Journal of food engineering 2020 v.284 pp. 110079
ISSN:
0260-8774
Subject:
coagulation,   etc   ; Salmonella Enteritidis; absorption; convection; egg proteins; eggs; foods; hysteresis; iron; magnetic fields; microbeads; pasteurization; thermosensitivity;     Show all 13 Subjects
Abstract:
... It is a challenge to pasteurize higher-viscosity and heat-sensitive foodstuffs via traditional convective heat transfer. Herein, we demonstrate the potential application of magnetic induction heating (MIH) as a novel uniform heating method applied in the pasteurization of liquid whole eggs (LWEs). Upon exposure to an alternating magnetic field (AMF), the magnetic microbeads with a large size (50 μ ...
DOI:
10.1016/j.jfoodeng.2020.110079

13. Induced fusion and aggregation of bacterial outer membrane vesicles: Experimental and theoretical analysis

Author:
Gnopo, Yehou M.D.; Misra, Aditya; Hsu, Hung-Lun; DeLisa, Matthew P.; Daniel, Susan; Putnam, David
Source:
Journal of colloid and interface science 2020 v.578 pp. 522-532
ISSN:
0021-9797
Subject:
coagulation,   etc   ; Escherichia coli; antigens; bacterial outer membranes; electrolytes; lipid composition; lipopolysaccharides; models; pH; vaccines;     Show all 10 Subjects
Abstract:
... Recombinantly engineered bacterial outer membrane vesicles (OMVs) are promising vaccine delivery vehicles. The diversity of exogenous antigens delivered by OMVs can be enhanced by induced fusion of OMV populations. To date there are no reports of induced fusion of bacterial OMVs. Here we measure the pH and salt-induced aggregation and fusion of OMVs and analyze the processes against the Derjaguin- ...
DOI:
10.1016/j.jcis.2020.04.068

14. Evaluation of enhanced coagulation combined with densadeg-ultrafiltration process in treating secondary effluent: Organic micro-pollutants removal, genotoxicity reduction, and membrane fouling alleviation

Author:
Chen, Zhiqiang; Yang, Boxuan; Wen, Qinxue; Chen, Chuxiao
Source:
Journal of hazardous materials 2020 v.396 pp. 122697
ISSN:
0304-3894
Subject:
coagulation,   etc   ; activated carbon; chlorides; fouling; genotoxicity; pollutants; potassium; total phosphorus; ultrafiltration; water quality; water reuse;     Show all 11 Subjects
Abstract:
... Conventional coagulation is widely used as an ultrafiltration membrane pretreatment process in wastewater reclamation, however it shows little ability to reduce organic micro-pollutants (OMPs) and genotoxicity. In this research, powdered activated carbon (PAC) and potassium ferrate were used respectively with polyaluminum chloride (PACl) to enhance coagulation. Filtration experiments of coagulatio ...
DOI:
10.1016/j.jhazmat.2020.122697

15. Rational design of porous starch/hyaluronic acid composites for hemostasis

Author:
Wang, Yanling; Liu, Guangwan; Wu, Lijuan; Qu, Hongyuan; Song, Deli; Huang, Hailong; Wu, Changlin; Xu, Min
Source:
International journal of biological macromolecules 2020 v.158 pp. 1319-1329
ISSN:
0141-8130
Subject:
blood coagulation,   etc   ; animal organs; biocompatibility; commercialization; hemolysis; hemorrhage; hemostasis; hyaluronic acid; sodium; starch; water binding capacity;     Show all 11 Subjects
Abstract:
... Effective hemorrhage control is pivotal for decreasing the trauma death both in civilian and military but has proven to be dauntingly challenging, especially for solid viscera and artery trauma. Here we report the fabrication of a novel starch-based hemostat, sodium trimethaphosphate (STMP)-crosslinked starch/hyaluronic acid (HA) (ScSH) porous composites. Aiming at hemostatic potential, physicoche ...
DOI:
10.1016/j.ijbiomac.2020.05.018

16. Effect of extracellular polymer substances on the tetracycline removal during coagulation process

Author:
Xu, Qiongying; Han, Bo; Wang, Huidi; Wang, Qiandi; Zhang, Weijun; Wang, Dongsheng
Source:
Bioresource technology 2020 v.309 pp. 123316
ISSN:
0960-8524
Subject:
coagulation,   etc   ; aluminum; binding sites; chlorides; density functional theory; polymers; proteins; spectroscopy; tetracycline; tryptophan; tyrosine;     Show all 11 Subjects
Abstract:
... In this study, the effect of extracellular polymer substances on the tetracycline removal under hydroxyl aluminium treatment was investigated, and the molecular mechanisms of extracellular polymeric substances mediated coagulation of tetracycline were also explored. The results show that the presence of extracellular polymeric substances could significantly enhance the removal efficiency of tetrac ...
DOI:
10.1016/j.biortech.2020.123316

17. Leaching behaviors and speciation of cadmium from river sediment dewatered using contrasting conditioning

Author:
Li, Tian; Shi, Yafei; Li, Xiaoran; Zhang, Huiqin; Pi, Kewu; Gerson, Andrea R.; Liu, Defu
Source:
Environmental pollution 2020 v.263 pp. 114427
ISSN:
0269-7491
Subject:
coagulation,   etc   ; bioavailability; cadmium; chlorides; dewatering; leachates; leaching; oxidation; polyacrylamide; risk; risk assessment; rivers; sediments;     Show all 13 Subjects
Abstract:
... Chemical conditioning is an effective strategy for improved river sediment dewatering affecting both the dewatering efficiency and subsequent resource utilization of the dewatered cake. Two types of conditioning agents, polyaluminium chloride (PAC)/cationic polyacrylamide (PAM) (coagulation precipitation conditioning agent, referred to as P–P conditioning) and ferrous activated sodium persulfate ( ...
DOI:
10.1016/j.envpol.2020.114427

18. Development of tissue factor-targeted liposomes for effective drug delivery to stroma-rich tumors

Author:
Shimizu, Kosuke; Takeuchi, Yoshihito; Otsuka, Kazuma; Mori, Tomoya; Narita, Yudai; Takasugi, Shohei; Magata, Yasuhiro; Matsumura, Yasuhiro; Oku, Naoto
Source:
Journal of controlled release 2020 v.323 pp. 519-529
ISSN:
0168-3659
Subject:
coagulation,   etc   ; antibodies; antineoplastic agents; cytotoxicity; fibroblasts; humans; in vivo studies; mice; neoplasm cells; neoplasms; stromal cells;     Show all 11 Subjects
Abstract:
... Tissue factor (TF), which is well known as a trigger molecule of extrinsic coagulation, is found in not only tumor cells but also in stromal cells in tumor tissues. Thus, TF is a candidate molecule to potentially enable targeting of both tumor cells and stromal cells for anti-cancer drug delivery. Herein, we prepared liposomes conjugated with the Fab’ fragment of anti-TF antibody (TF Ab-Lip) and e ...
DOI:
10.1016/j.jconrel.2020.04.043

19. Nucleic acid-based drug delivery strategies

Author:
Tan, Xuyu; Jia, Fei; Wang, Ping; Zhang, Ke
Source:
Journal of controlled release 2020 v.323 pp. 240-252
ISSN:
0168-3659
Subject:
blood coagulation,   etc   ; DNA; RNA; drug delivery systems; drugs; encapsulation; hydrophilicity; immune system; nanomaterials; oligonucleotides;     Show all 10 Subjects
Abstract:
... Nucleic acids have not been widely considered as an optimal material for drug delivery. Indeed, unmodified nucleic acids are enzymatically unstable, too hydrophilic for cell uptake and payload encapsulation, and may cause unintended biological responses such as immune system activation and prolongation of the blood coagulation pathway. Recently, however, three major areas of development surroundin ...
DOI:
10.1016/j.jconrel.2020.03.040

20. Ash deposition during pressurized oxy-fuel combustion of Zhundong coal in a lab-scale fluidized bed

Author:
Qiu, Xinglei; Duan, Lunbo; Duan, Yuanqiang; Li, Bin; Lu, Duanfeng; Zhao, Changsui
Source:
Fuel processing technology 2020 v.204 pp. 106411
ISSN:
0378-3820
Subject:
coagulation,   etc   ; carbon dioxide; coal; combustion; fluidized beds; iron; nitrogen; oxygen; partial pressure; silicon; sulfur;     Show all 11 Subjects
Abstract:
... The paper presents the ash deposition behavior during pressurized oxy-fuel fluidized bed combustion (POFBC) of Zhundong coal at 0.3 MPa, which has never been reported before. Ash deposits collected from different positions (windward, leeward and vertical sides) of the probe under different atmospheres were investigated in detail. The results showed that the inside deposits, i.e. the initial deposi ...
DOI:
10.1016/j.fuproc.2020.106411