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1. Recent progress in assembly strategies of nanomaterials-based ultrasensitive electrochemiluminescence biosensors for food safety and disease diagnosis

Author:
Lu Peng; Pengcheng Li; Jia Chen; Anping Deng; Jianguo Li
Source:
Talanta 2023 v.253 pp. 123906
ISSN:
0039-9140
Subject:
disease diagnosis,   etc   ; biosensors; electrochemiluminescence; food contamination; nanomaterials;     Show all 5 Subjects
Abstract:
... The Electrochemiluminescence (ECL)-based biosensors have received considerable attention in food contaminants and disease diagnosis, due to their fascinating advantages such as low cost, fast analysis speed, wide linear range, high sensitivity, and excellent anti-interference ability. Meanwhile, with the vigorous development and improvement of nanotechnology, biosensor assembly strategies tend to ...
DOI:
10.1016/j.talanta.2022.123906

2. Microfluidic deformability cytometry: A review

Author:
Yao Chen; Kefan Guo; Lin Jiang; Shu Zhu; Zhonghua Ni; Nan Xiang
Source:
Talanta 2023 v.251 pp. 123815
ISSN:
0039-9140
Subject:
disease diagnosis,   etc   ; acoustics; cell cycle; cell growth; drugs; extrusion; hydrodynamics; medicine; microfluidic technology;     Show all 9 Subjects
Abstract:
... Cell deformability plays an important role in cellular processes and functions, including cell growth and differentiation, as well as cell transfer and cell cycle. Measuring deformability at the single-cell level has attracted great interest in biomedicine owing to its importance in various applications, such as cell separation, disease diagnosis, and drug screening. Therefore, an accurate, robust ...
DOI:
10.1016/j.talanta.2022.123815

3. A survey on using deep learning techniques for plant disease diagnosis and recommendations for development of appropriate tools

Author:
Aanis Ahmad; Dharmendra Saraswat; Aly El Gamal
Source:
Smart agricultural technology 2023 v.3 pp. 100083
ISSN:
2772-3755
Subject:
disease diagnosis,   etc   ; data collection; disease control; disease severity; farmers; humans; image analysis; precision agriculture; surveys;     Show all 9 Subjects
Abstract:
... Several factors associated with disease diagnosis in plants using deep learning techniques must be considered to develop a robust system for accurate disease management. A considerable number of studies have investigated the potential of deep learning techniques for precision agriculture in the last decade. However, despite the range of applications, several gaps within plant disease research are ...
DOI:
10.1016/j.atech.2022.100083

4. Biosensing strategies (approaches) for diagnosis and monitoring of multiple sclerosis

Author:
Marina Serin; Pinar Kara
Source:
Talanta 2023 v.252 pp. 123794
ISSN:
0039-9140
Subject:
disease diagnosis,   etc   ; autoimmune diseases; biomarkers; biosensors; central nervous system; cost effectiveness; disease control; electrophoresis; human resources; patients; sclerosis;     Show all 11 Subjects
Abstract:
... Multiple sclerosis is a recurrent and progressive inflammatory autoimmune disease causing demyelination in the central nervous system. Nowadays, the number of MS patients is increasing, but the diagnostic process and disease management are still quite difficult and costly and time consuming. The combination of methods used for clinical MS diagnosis mainly relies on MRI, that cannot be used as rout ...
DOI:
10.1016/j.talanta.2022.123794

5. In-situ and amplification-free imaging of hERG ion channels at single-cell level using a unique core-molecule-shell-secondary antibody SERS nanoprobe

Author:
Wen-Shu Zhang; Xiao-Peng Liu; Shuai Yue; Ya-Ning Wang; Yue Wang; Zhang-Run Xu
Source:
Talanta 2023 v.253 pp. 123900
ISSN:
0039-9140
Subject:
disease diagnosis,   etc   ; antibodies; cell structures; drug development; genes; gold; humans; immune response; immunoglobulin G; nanoparticles; potassium channels; silver;     Show all 12 Subjects
Abstract:
... Research on ion channels and their monoclonal antibodies plays a critical role in drug development and disease diagnosis. The current ion channel researches are often not conducted in the microenvironment for cells survival, which restricts the mechanism study of the links between the cell structure and the ion channel function. In this work, we synthesized gold core-4-mercaptobenzonitrile-sliver ...
DOI:
10.1016/j.talanta.2022.123900

6. Diagnosis of grape leaf diseases using automatic K-means clustering and machine learning

Author:
Seyed Mohamad Javidan; Ahmad Banakar; Keyvan Asefpour Vakilian; Yiannis Ampatzidis
Source:
Smart agricultural technology 2023 v.3 pp. 100081
ISSN:
2772-3755
Subject:
disease diagnosis,   etc   ; color; computer vision; crop yield; grapes; leaf blight; leaves; measles; principal component analysis; product quality; support vector machines;     Show all 11 Subjects
Abstract:
... Plant diseases often reduce crop yield and product quality; therefore, plant disease diagnosis plays a vital role in farmers’ management decisions. Visual crop inspections by humans are time-consuming and challenging tasks and, practically, can only be performed in small areas at a given time, especially since many diseases have similar symptoms. An intelligent machine vision monitoring system for ...
DOI:
10.1016/j.atech.2022.100081

7. A DNAzyme-based normalized fluorescence strategy for direct quantification of endogenous zinc in living cells

Author:
Xuanhao Zhang; Zhi-Ling Song; Qiqi Chao; Qian Li; Rongmei Kong; Gao-Chao Fan; Xiliang Luo
Source:
Chemical communications 2022 v.58 no.4 pp. 577-580
ISSN:
1364-548X
Subject:
disease diagnosis,   etc   ; fluorescence; fluorescent dyes; zinc;     Show all 4 Subjects
Abstract:
... Taking the maximum fluorescence of an identical fluorophore as a reference, a DNAzyme-based normalized strategy is developed to unify the output signals under external interferences. This makes it possible to directly quantify endogenous zinc in living cells by in situ fluorescence imaging, implying promising potential in fundamental study and early disease diagnosis. ...
DOI:
10.1039/d1cc06471a

8. Optically Programmable Plasmon Enhanced Fluorescence-Catalytic Hairpin Assembly Signal Amplification Strategy for Spatiotemporally Precise Imaging

Author:
Tingting Zhao; Xiaomei Sun; Jing Chen; Dan Li; Wei Cao; Shuwei Chen; Yue Yin; Shenghao Xu; Xiliang Luo
Source:
Analytical chemistry 2022 v.94 no.13 pp. 5399-5405
ISSN:
1520-6882
Subject:
disease diagnosis,   etc   ; analytical chemistry; detection limit; microRNA;     Show all 4 Subjects
Abstract:
... Signal amplification strategies with spatiotemporally high sensitivity can provide more accurate information and hold great promise for improving the accuracy of disease diagnosis. Herein, a 808 nm near-infrared (NIR) light-activated plasmon enhanced fluorescence-catalytic hairpin assembly (PEF-CHA) signal amplification strategy was proposed for spatiotemporally controllable precise imaging of miR ...
DOI:
10.1021/acs.analchem.2c00150

9. Systems biochemistry to “deorphanize” human mitochondrial proteome

Author:
Francois Miros; Ran Liu; Hongying Shen
Source:
Molecular cell 2022 v.82 no.15 pp. 2735-2737
ISSN:
1097-2765
Subject:
disease diagnosis,   etc   ; humans; lipidomics; mitochondria; proteome; proteomics;     Show all 6 Subjects
Abstract:
... Rensvold, Shishkova, et al. (2022) apply an integrated systems biology approach spanning proteomics, lipidomics, and metabolomics to a collection of CRISPR knockout cells targeting 116 distinct human mitochondrial proteins, revealing new mitochondrial biology and guiding orphan disease diagnosis. ...
DOI:
10.1016/j.molcel.2022.07.005

10. Keystone taxa: an emerging area of microbiome research for future disease diagnosis and health safety in human

Author:
Urmi Das; Ahmed M. El-Shehawi; Sarah Albogami; Ahmad Humayan Kabir
Source:
Microbiological research 2022 pp. 127203
ISSN:
0944-5013
Subject:
disease diagnosis,   etc   ; commensalism; humans; microbiome; research; therapeutics;     Show all 6 Subjects
Abstract:
... Keystone taxa in the human microbiome, which are unique and are constantly changing, play a crucial role in commensalism and the etiology of disease in humans, which has opened a new door to diagnostic and therapeutic possibilities. In this review, we discuss the conceptual milestones of keystone taxa, factors, and scientific techniques connected to the keystone taxa identified in humans. We provi ...
DOI:
10.1016/j.micres.2022.127203

11. Review of the use of nanodevices to detect single molecules

Author:
Takahito Ohshiro; Masateru Taniguchi
Source:
Analytical biochemistry 2022 v.654 pp. 114645
ISSN:
0003-2697
Subject:
disease diagnosis,   etc   ; biochemistry; chemical species; drugs; nanopores;     Show all 5 Subjects
Abstract:
... The development of methodologies to identify single molecules and/or to detect/monitor molecular behavior at the single-molecule level is one of the important research topics in chemistry and biology. In this review, we summarized the state-of-the-art of single molecule measurement methods and its latest applications using nanodevices integrated with molecular-size functional nanostructures, nanop ...
DOI:
10.1016/j.ab.2022.114645

12. An Exploratory Study on Vectorcardiographic Identification of the Site of Origin of Focally Induced Premature Depolarizations in Horses, Part II: The Ventricles

Author:
Glenn Van Steenkiste; Tammo Delhaas; Ben Hermans; Lisse Vera; Annelies Decloedt; Gunther van Loon
Source:
Animals 2022 v.12 no.5 pp. -
ISSN:
2076-2615
Subject:
disease diagnosis,   etc   ; anesthesia; catheters; echocardiography; electrocardiography; humans; models;     Show all 7 Subjects
Abstract:
... In human cardiology, the anatomical origin of ventricular premature depolarizations (VPDs) is determined by the characteristics of a 12-lead electrocardiogram (ECG). Former studies in horses had contradictory results regarding the diagnostic value of the 12-lead ECG and vectorcardiography (VCG), which results were attributed to the different cardiac conduction system in this species. The objective ...
DOI:
10.3390/ani12050550

13. MXene/ZIF-67/PAN Nanofiber Film for Ultra-sensitive Pressure Sensors

Author:
Xiyao Fu; Junzhi Li; Dongdong Li; Lianjia Zhao; Zeyu Yuan; Valerii Shulga; Wei Han; Lili Wang
Source:
ACS applied materials & interfaces 2022 v.14 no.10 pp. 12367-12374
ISSN:
1944-8252
Subject:
disease diagnosis,   etc   ; artificial intelligence; electronic equipment; electronics; nanofibers;     Show all 5 Subjects
Abstract:
... Flexible pressure sensors may be used in electronic skin (e-skin), artificial intelligence devices, and disease diagnosis, which require a large response range and high sensitivity. An appropriate design of the structure of the active layer can help effectively solve this problem. Herein, we aim at developing a wearable pressure sensor using the MXene/ZIF-67/polyacrylonitrile (PAN) nanofiber film, ...
DOI:
10.1021/acsami.1c24655

14. A New Sternorrhynchan Genus and Species from the Triassic Period of China That Is Likely Related to Protopsyllidioid (Insecta, Hemiptera)

Author:
Diying Huang; Marina Hakim; Yanzhe Fu; André Nel
Source:
Insects 2022 v.13 no.7 pp. -
ISSN:
2075-4450
Subject:
disease diagnosis,   etc   ; Hemiptera; Triassic period; phylogeny; wings; China;     Show all 6 Subjects
Abstract:
... Triassopsyllidiida pectinata gen. et sp. nov. is described from the latest Middle Triassic Tongchuan biota of China and tentatively attributed to the superfamily Protopsyllidioidea. Its forewing venation is unique among this superfamily in the anteriorly pectinate vein ScP + RA and the presence of a veinlet between R and M + CuA. Its exact position in this group remains uncertain, mainly because o ...
DOI:
10.3390/insects13070592

15. LncRNA-TUG1 Downregulation is Correlated with the Development of Progressive Chronic Kidney Disease Among Patients with Congestive Heart Failure

Author:
Wei Zhao; Yuan Zhang; Mingzhu Zhang; Yong Zhi; Xiaohan Li; Xuezheng Liu
Source:
Molecular biotechnology 2022 v.64 no.5 pp. 493-498
ISSN:
1073-6085
Subject:
disease diagnosis,   etc   ; biotechnology; heart failure; kidney diseases; kidneys;     Show all 5 Subjects
Abstract:
... TUG1 is an lncRNA that plays a critical role in kidney injury. Our preliminary sequencing analysis showed altered TUG1 expression in both congestive heart failure (CHF) patients and CHF patients complicated with chronic kidney disease (CKD). We then studied the role of TUG1 in these two diseases. We enrolled 120 CHF patients without obvious complications, 60 CHF patients complicated with CKD, and ...
DOI:
10.1007/s12033-021-00427-3

16. Apoptotic bodies for advanced drug delivery and therapy

Author:
Min Zhou; Yong-Jiang Li; Yu-Cheng Tang; Xin-Yan Hao; Wen-Jie Xu; Da-Xiong Xiang; Jun-Yong Wu
Source:
Journal of controlled release 2022 v.351 pp. 394-406
ISSN:
0168-3659
Subject:
disease diagnosis,   etc   ; apoptosis; biochemical compounds; biocompatibility; drugs; exosomes; immunotherapy;     Show all 7 Subjects
Abstract:
... Extracellular vesicles (EVs) have emerged as promising candidates for multiple biomedical applications. Major types of EVs include exosomes, microvesicles, and apoptotic bodies (ABs). ABs are conferred most properties from parent cells in the final stages of apoptosis. A wide variety of sources and stable morphological features are endowed to ABs by the rigorous apoptotic program. ABs accommodate ...
DOI:
10.1016/j.jconrel.2022.09.045

17. A high-integrated DNA biocomputing platform for MicroRNA sensing in living cells

Author:
Wen Yi Lv; Chun Hong Li; Hua Rong Lin; Li Li Li; Hong Yan Zou; Chun Mei Li; Shu Jun Zhen; Cheng Zhi Huang
Source:
Biosensors & bioelectronics 2022 v.207 pp. 114183
ISSN:
0956-5663
Subject:
disease diagnosis,   etc   ; DNA; biosensors; genes; microRNA; neoplasm cells; therapeutics;     Show all 7 Subjects
Abstract:
... DNA logic computing has captured increasing interest due to its ability to assemble programmable DNA computing elements for disease diagnosis, gene regulation, and targeted therapy. In this work, we developed an aptamer-equipped high-integrated DNA biocomputing platform (HIDBP-A) with a dual-recognition function that enabled cancer cell targeting. Dual microRNAs were the input signals and can perf ...
DOI:
10.1016/j.bios.2022.114183

18. The recent development of nanozymes for food quality and safety detection [Erratum: July 2022, v.10(27); p.5291]

Author:
Yanyan Huang; Xiaoyu Mu; Jiayi Wang; Yue Wang; Jing Xie; Ruifeng Ying; Erzheng Su
Source:
Journal of materials chemistry B 2022 v.10 no.9 pp. 1359-1368
ISSN:
2050-7518
Subject:
disease diagnosis,   etc   ; chemistry; environmental protection; food analysis; food quality;     Show all 5 Subjects
Abstract:
... As potential mimics of natural enzymes, nanozymes can overcome many disadvantages associated with the use of natural enzymes, such as the need for complex preparation and purification processes, high cost, poor stability, and low recycling efficiency. Utilizing the unique advantages of nanomaterials, nanozymes have been widely used in biosensing, environmental protection, disease diagnosis and tre ...
DOI:
10.1039/d1tb02667d

19. Putting surface-enhanced Raman spectroscopy to work for nanozyme research: Methods, materials and applications

Author:
Ming Mu; Sisi Wen; Saizhen Hu; Bing Zhao; Wei Song
Source:
Trends in analytical chemistry 2022 v.152 pp. 116603
ISSN:
0165-9936
Subject:
disease diagnosis,   etc   ; Raman spectroscopy; analytical chemistry; food safety; immunoassays; therapeutics;     Show all 6 Subjects
Abstract:
... Some functional nanomaterials can be used as both nanozymes and SERS substrates, thus a variety of nanozyme-SERS systems have been constructed, which have been broadly applicable in many fields. In this review, we will systematically present the recent development of the fabrication, properties and applications of the nanozyme-SERS systems. First, the fundamentals of the nanozymes and SERS techniq ...
DOI:
10.1016/j.trac.2022.116603

20. Skin bioelectronics towards long-term, continuous health monitoring

Author:
Yan Wang; Hossam Haick; Shuyang Guo; Chunya Wang; Sunghoon Lee; Tomoyuki Yokota; Takao Someya
Source:
Chemical Society reviews 2022 v.51 no.9 pp. 3759-3793
ISSN:
1460-4744
Subject:
disease diagnosis,   etc   ; biocompatibility; disease prevention; electrophysiology; health services; precision medicine;     Show all 6 Subjects
Abstract:
... Skin bioelectronics are considered as an ideal platform for personalised healthcare because of their unique characteristics, such as thinness, light weight, good biocompatibility, excellent mechanical robustness, and great skin conformability. Recent advances in skin-interfaced bioelectronics have promoted various applications in healthcare and precision medicine. Particularly, skin bioelectronics ...
DOI:
10.1039/d2cs00207h