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1. Efficacy and safety of immediate oral intake in patients with mild acute pancreatitis: A randomized controlled trial

Author:
Horibe, Masayasu; Iwasaki, Eisuke; Nakagawa, Atsuo; Matsuzaki, Juntaro; Minami, Kazuhiro; Machida, Yujiro; Tamagawa, Hiroki; Takimoto, Yoichi; Ueda, Masahiro; Katayama, Tadashi; Kawasaki, Shintaro; Matsushita, Misako; Seino, Takashi; Fukuhara, Seiichiro; Kanai, Takanori
Source:
Nutrition 2020 v.74 pp. 110724
ISSN:
0899-9007
Subject:
disease severity,   etc   ; confidence interval; dietary fat; enteral feeding; narcotics; pain; pancreatitis; patients; randomized clinical trials;     Show all 9 Subjects
Abstract:
... Early enteral nutrition is recommended for patients with severe acute pancreatitis (AP); however, nutritional management strategies for patients with mild AP have not been established. The aim of this study was to evaluate the benefits and safety of immediate oral intake of low-fat solid food in patients with mild AP who were allowed to take opioid analgesics.In this single-center randomized study ...
DOI:
10.1016/j.nut.2020.110724

2. Phase angle could be a marker of microvascular damage in systemic sclerosis

Author:
Gigante, Antonietta; Gasperini, Maria Ludovica; Rosato, Edoardo; Navarini, Luca; Margiotta, Domenico; Afeltra, Antonella; Muscaritoli, Maurizio
Source:
Nutrition 2020 v.73 pp. 110730
ISSN:
0899-9007
Subject:
disease severity,   etc   ; autoimmune diseases; endothelial cells; females; fibrosis; males; patients; sclerosis; vascular endothelial growth factors;     Show all 9 Subjects
Abstract:
... Systemic sclerosis (SSc) is an autoimmune disease characterized by endothelial dysfunction with fibrosis of skin and internal organs. Integrity of the endothelial cell is important to its physiologic function such as production of angiogenetic factors. The aim of this study was to assess whether phase angle (PhA) is altered in patients with SSc and whether its values correlate with vascular endoth ...
DOI:
10.1016/j.nut.2020.110730

3. Past and present of a Mediterranean small-scale fishery: the Greek sponge fishery—its resilience and sustainability

Author:
Fourt, Maïa; Faget, Daniel; Dailianis, Thanos; Koutsoubas, Drosos; Pérez, Thierry
Source:
Regional environmental change 2020 v.20 no.1 pp. 1
ISSN:
1436-3798
Subject:
disease severity,   etc   ; disease outbreaks; epizootic diseases; fishermen; global change; human population; monitoring; overfishing; politics; socioeconomics; Greece;     Show all 11 Subjects
Abstract:
... Global change impacts Mediterranean fisheries and the dependent human populations. Overfishing and epizootic diseases related to extreme climatic events are currently accepted as the main threats to the production of commercial bath sponges. Believing that other factors could have impacted this insular fishery, we assembled a 150-year-long series of sponge fishing data for Greece that was analyzed ...
DOI:
10.1007/s10113-020-01581-1

4. Recent advances in heparinization of polymeric membranes for enhanced continuous blood purification

Author:
Shan, Liang; Sun, Yunbo; Shan, Feng; Li, Li; Xu, Zhi Ping
Source:
Journal of materials chemistry B 2020 v.8 no.5 pp. 878-894
ISSN:
2050-7518
Subject:
disease severity,   etc   ; anticoagulants; artificial membranes; blood; blood coagulation; chemistry; expert opinion; filters; filtration; heparin; patients; polymers;     Show all 12 Subjects
Abstract:
... Continuous blood purification technology such as hemodiafiltration has been used worldwide for saving patients suffering from severe diseases or organ function failure, especially in the intensive care unit and emergency setting. The filters as core devices are commonly made of polymer materials as hollow fiber membranes. However, the membrane is often inductively blocked by blood clot formation d ...
DOI:
10.1039/c9tb02515d

5. Current advances in the detection of neurotransmitters by nanomaterials: An update

Author:
Arumugasamy, Shiva Kumar; Chellasamy, Gayathri; Gopi, Sivalingam; Govindaraju, Saravanan; Yun, Kyusik
Source:
Trends in analytical chemistry 2020 v.123 pp. 115766
ISSN:
0165-9936
Subject:
disease severity,   etc   ; Alzheimer disease; Parkinson disease; brain; death; diagnostic techniques; monitoring; nanomaterials; neurotransmitters; patients; synaptic transmission;     Show all 11 Subjects
Abstract:
... Neurotransmitters (NTs) are chemical messengers in the synaptic transmission process. NTs play important roles in human activities, and imbalanced NTs levels in the body lead to severe diseases such as Alzheimer's and Parkinson's diseases. The accurate diagnosis of NTs imbalances has been identified only after patient death through identifying plaques in the brain. Hence, the diagnosis and monitor ...
DOI:
10.1016/j.trac.2019.115766

6. ER morphology and endo-lysosomal crosstalk: Functions and disease implications

Author:
Lee, Crystal A.; Blackstone, Craig
Source:
Biochimica et biophysica acta 2020 v.1865 no.1 pp. 158544
ISSN:
1388-1981
Subject:
disease severity,   etc   ; calcium; cholesterol; endomembrane system; endoplasmic reticulum; endosomes; lysosomes; nervous system; nuclear membrane; proteins;     Show all 10 Subjects
Abstract:
... The endoplasmic reticulum (ER) is a continuous endomembrane system comprising the nuclear envelope, ribosome-studded sheets, dense peripheral matrices, and an extensive polygonal network of interconnected tubules. In addition to performing numerous critical cellular functions, the ER makes extensive contacts with other organelles, including endosomes and lysosomes. The molecular and functional cha ...
DOI:
10.1016/j.bbalip.2019.158544
PubMed:
31678515
PubMed Central:
PMC6904894

7. Assessment of the impact of climate change on the latency period of leaf rust on triticale in Poland

Author:
Wójtowicz, Andrzej; Wójtowicz, Marek; Sigvald, Roland; Czernecki, Bartosz; Ratajkiewicz, Henryk; Łacka, Agnieszka; Zacharczuk, Maciej; Pasternak, Maria
Source:
Acta agriculturæ Scandinavica 2020 v.70 no.3 pp. 195-207
ISSN:
1651-1913
Subject:
disease severity,   etc   ; climate change; climate models; disease outbreaks; leaf rust; meteorological data; prediction; probability; temperature; triticale; Poland;     Show all 11 Subjects
Abstract:
... Disease development in plants is strongly dependent on weather conditions, with temperature playing a particularly significant role by influencing latency period duration. Using two models describing the relationship between latency period and temperature, we performed simulations aimed at predicting changes in the latency period of leaf rust (Puccina recondita f. sp. tritici) on triticale in resp ...
DOI:
10.1080/09064710.2019.1696394

8. Behavioral adaptations in a relapsing mouse model of colitis

Author:
Matisz, Chelsea E.; Vicentini, Fernando A.; Hirota, Simon A.; Sharkey, Keith A.; Gruber, Aaron J.
Source:
Physiology & behavior 2020 v.216 pp. 112802
ISSN:
0031-9384
Subject:
disease severity,   etc   ; animal disease models; anxiety; chronic exposure; cognitive disorders; colitis; dextran; digestive system; inflammation; memory; sodium sulfate;     Show all 11 Subjects
Abstract:
... Inflammatory bowel disease (IBD) is characterized by relapsing periods of gut inflammation, and is comorbid with depression, anxiety, and cognitive deficits. Animal models of IBD that explore the behavioral consequences almost exclusively use acute models of gut inflammation, which fails to recapitulate the cyclic, chronic nature of IBD. This study sought to identify behavioral differences in digg ...
DOI:
10.1016/j.physbeh.2020.112802

9. Natural infection of a variant pseudorabies virus leads to bovine death in China

Author:
Cheng, Zilong; Kong, Zhengjie; Liu, Peng; Fu, Zhendong; Zhang, Jiandong; Liu, Mengda; Shang, Yingli
Source:
Transboundary and emerging diseases 2020 v.67 no.2 pp. 518-522
ISSN:
1865-1674
Subject:
disease severity,   etc   ; Suid alphaherpesvirus 1; cattle; cattle diseases; cattle industry; emerging diseases; humans; public health; swine; wild animals; China;     Show all 11 Subjects
Abstract:
... Pseudorabies virus (PRV) infects numerous species of domestic and wild animals leading to severe diseases especially in swine and cattle. Since 2011, the variant PRVs were identified in pigs, which were genetically different from classic strains. Although variant PRV infection is widely observed in pigs, there is still no report of variant PRV infection in cattle. Here, we reported a natural infec ...
DOI:
10.1111/tbed.13427

10. Serum D‐lactate concentrations in dogs with parvoviral enteritis

Author:
Venn, Emilee C.; Barnes, Alex J.; Hansen, Ryan J.; Boscan, Pedro L.; Twedt, David C.; Sullivan, Lauren A.
Source:
Journal of veterinary internal medicine 2020 v.34 no.2 pp. 691-699
ISSN:
0891-6640
Subject:
disease severity,   etc   ; animal viruses; blood gases; blood serum; dogs; electrolytes; enteritis; epithelium; intestinal microorganisms; intestines; lactic acid; observational studies;     Show all 12 Subjects
Abstract:
... BACKGROUND: Dogs infected with canine parvovirus (CPV) have compromised intestinal epithelial barrier integrity. Production of D‐lactate by enteric bacteria may directly reflect disease severity or contribute to metabolic acid‐base status in these dogs. HYPOTHESIS: Serum D‐lactate concentration will be increased in CPV dogs compared to healthy controls and correlate with markers of disease severit ...
DOI:
10.1111/jvim.15688
PubMed:
31919893
PubMed Central:
PMC7096611

11. Perceptions among the U.S. population of value of Japanese encephalitis (JE) vaccination for travel to JE-endemic countries

Author:
Hills, Susan L.; Fischer, Marc; Biggerstaff, Brad J.
Source:
Vaccine 2020 v.38 no.9 pp. 2117-2121
ISSN:
0264-410X
Subject:
disease severity,   etc   ; Japanese encephalitis virus; adults; adverse effects; endemic diseases; risk; surveys; travel; vaccination; viral encephalitis; viral vaccines; United States;     Show all 12 Subjects
Abstract:
... Japanese encephalitis (JE) is a rare but potentially severe disease among travelers. JE vaccine in the United States costs $500–$600 for a 2-dose series and is safe and effective but rare serious adverse events can occur. Our survey investigated likelihood of vaccine receipt for travel.An electronically-administered survey was conducted among U.S. adults. Participants were presented a hypothetical ...
DOI:
10.1016/j.vaccine.2020.01.048

12. Invasive pneumococcal disease among hospitalized children in Brazil before and after the introduction of a pneumococcal conjugate vaccine

Author:
Berezin, Eitan Naaman; Jarovsky, Daniel; Cardoso, Maria Regina Alves; Mantese, Orlando Cesar
Source:
Vaccine 2020 v.38 no.7 pp. 1740-1745
ISSN:
0264-410X
Subject:
disease severity,   etc   ; Streptococcus pneumoniae; bacteremia; children; death; meningitis; monitoring; mortality; patients; pneumonia; serotypes; vaccination; vaccines; Brazil; Latin America;     Show all 15 Subjects
Abstract:
... Most of the available data on invasive pneumococcal disease in Latin America are derived from laboratory-based surveillance systems. There is a lack of epidemiological data on the disease severity and mortality from hospitalized patients with pneumococcal infection.In this hospital-based retrospective historical series of hospitalized children with laboratory-confirmed IPD, we evaluated changes in ...
DOI:
10.1016/j.vaccine.2019.12.038

13. A systematic review of body mass gain after deep brain stimulation of the subthalamic nucleus in patients with Parkinson's disease

Author:
Steinhardt, Julia; Münte, Thomas F.; Schmid, Sebastian M.; Wilms, Britta; Brüggemann, Norbert
Source:
Obesity reviews 2020 v.21 no.2 pp. e12955
ISSN:
1467-7881
Subject:
disease severity,   etc   ; Parkinson disease; adverse effects; body mass index; brain; metabolic diseases; overweight; patients; systematic review; weight loss;     Show all 10 Subjects
Abstract:
... This systematic review investigated the effects of deep brain stimulation of the subthalamic nucleus on extent and time course of body mass changes in patients with Parkinson's disease. A computerized search identified relevant articles using a priori defined inclusion and exclusion criteria. A descriptive analysis was calculated for the main outcome parameters body mass and BMI. Thirty‐eight out ...
DOI:
10.1111/obr.12955

14. Pneumococcal conjugate serotype distribution and predominating role of serotype 3 in German adults with community-acquired pneumonia

Author:
Forstner, Christina; Kolditz, Martin; Kesselmeier, Miriam; Ewig, Santiago; Rohde, Gernot; Barten-Neiner, Grit; Rupp, Jan; Witzenrath, Martin; Welte, Tobias; Pletz, Mathias W.
Source:
Vaccine 2020 v.38 no.5 pp. 1129-1136
ISSN:
0264-410X
Subject:
disease severity,   etc   ; Streptococcus pneumoniae; adults; antigen detection; cohort studies; herds; hospitals; oxygen; patients; pneumonia; serotypes; urine; vaccination; vaccines; Germany;     Show all 15 Subjects
Abstract:
... Implementation of the 7-valent pneumococcal conjugate vaccine (PCV7) in infant vaccination programs has substantially reduced the burden of PCV7 serotypes also in adult community-acquired pneumonia (CAP). Currently, it is unclear, if this extensive herd protection effect can be extrapolated to the additional 6 serotypes included in the 13-valent pneumococcal conjugate vaccine (PCV13), which replac ...
DOI:
10.1016/j.vaccine.2019.11.026

15. Nighttime Application of UV-C to Control Cucumber Powdery Mildew

Author:
Patel, Jaimin S.; Radetsky, Leora C.; Nagare, Rohan; Rea, Mark S.
Source:
Plant health progress 2020 v.21 no.1 pp. 40-46
ISSN:
1535-1025
Subject:
disease severity,   etc   ; Podosphaera xanthii; crops; cucumbers; grapes; growers; leaf area; light intensity; pathogens; powdery mildew; rosemary; strawberries; tomatoes; ultraviolet radiation;     Show all 14 Subjects
Abstract:
... Nonionizing, ultraviolet (UV) radiation is effective for mitigating powdery mildew associated with a variety of crops including strawberry, grapes, rosemary, tomato, rose, and cucumber. The effectiveness of UV radiation depends upon the dose (irradiance × duration), the frequency of dosing, the time of application, and the sensitivity of the crop to UV radiation. Reported here are the results of t ...
DOI:
10.1094/PHP-11-19-0081-RS

16. Retrospective evaluation of the use of parenteral nutrition in hospitalized nondomestic ruminants

Author:
Mulreany, Lauren M.; Kinney, Matthew E.; Clancy, Meredith M.; Lamberski, Nadine; Werre, Stephen R.
Source:
Journal of zoo and wildlife medicine 2020 v.50 no.4 pp. 853-860
ISSN:
1937-2825
Subject:
disease severity,   etc   ; adults; adverse effects; appetite; equipment; hospitals; hyperglycemia; hypokalemia; malnutrition; parenteral feeding; retrospective studies; ruminants; zoo animals;     Show all 13 Subjects
Abstract:
... Parenteral nutrition (PN) is one method of providing nutrient support to hospitalized, nondomestic ruminants that have a decreased appetite in hospital or have high metabolic demands caused by illness. There are a limited number of published reports of the use of PN in nondomestic ruminants. A retrospective evaluation of PN use in adult (>6 mo of age) hospitalized ruminants at the San Diego Zoo Sa ...
DOI:
10.1638/2019-0034

17. lncRNA PCAT18 inhibits proliferation, migration and invasion of gastric cancer cells through miR-135b suppression to promote CLDN11 expression

Author:
Zhang, Xiao-Zhan; Mao, Hong-Li; Zhang, Shi-Jie; Sun, Li; Zhang, Wen-Jing; Chen, Qing-Zhou; Wang, Lei; Liu, Hong-Chun
Source:
Life sciences 2020 v.249 pp. 117478
ISSN:
0024-3205
Subject:
disease severity,   etc   ; Western blotting; in vivo studies; luciferase; metastasis; neoplasm cells; protein content; quantitative polymerase chain reaction; reporter genes; reverse transcriptase polymerase chain reaction; stomach neoplasms; transcription (genetics);     Show all 12 Subjects
Abstract:
... Gastric cancer is a severe disease with a high occurrence rate worldwide. And lncRNAs are demonstrated to be responsible for cancer growth and metastasis. So, it is of great importance to explore the lncRNAs involved mechanism of gastric cancer occurrence and development deeply.Transfection was conducted to build over-expression and down-expression models. Moreover, RT-qPCR and western blot were u ...
DOI:
10.1016/j.lfs.2020.117478

18. Nutrition, malnutrition, and leishmaniasis

Author:
Amuche, Nweze Justus; Innocent, Nweze Emeka; Nweze, Justus Amuche; Nweze, Emeka Innocent; Onoja, Uwakwe Simon
Source:
Nutrition 2020 v.73 pp. 110712
ISSN:
0899-9007
Subject:
disease severity,   etc   ; Phlebotominae; blood serum; body weight; diet; evolution; host seeking; indigenous species; infectious diseases; larvae; leishmaniasis; malnutrition; nutritional status; parasites; pathogens; pathophysiology; therapeutics; vector competence;     Show all 18 Subjects
Abstract:
... Leishmaniasis is a vector-borne infectious disease with a long history of infecting humans and other animals. It is a known emerging or resurging disease. The host nutritional state has an indispensable role in defense against pathogens. The host defense system disorganization as a result of undernutrition is responsible for asymptomatic infections and even severe diseases. Host susceptibility and ...
DOI:
10.1016/j.nut.2019.110712

19. Cost-effectiveness of inactivated influenza vaccination in children with medical risk conditions in the Netherlands

Author:
Naber, Steffie K.; Bruijning-Verhagen, Patricia C.J.L.; de Hoog, Marieke L.A.; van Giessen, Anoukh
Source:
Vaccine 2020 v.38 no.17 pp. 3387-3396
ISSN:
0264-410X
Subject:
disease severity,   etc   ; children; cost effectiveness; decision support systems; influenza; influenza vaccination; influenza vaccines; models; mortality; quality-adjusted life year; risk; Netherlands;     Show all 12 Subjects
Abstract:
... In many countries, annual immunization with inactivated influenza vaccine (IIV) is recommended for children with medical risk conditions. Prior cost-effectiveness analyses found such immunization to be cost saving, but assumed effectiveness against non-severe influenza outcomes and a higher effectiveness against severe influenza outcomes than recent studies would suggest. However, recent vaccine s ...
DOI:
10.1016/j.vaccine.2020.01.057

20. Shaping meeting to explore the value of a coordinated work plan for epidemic and pandemic influenza vaccine preparedness

Author:
Ruscio, Bruce; Bolster, Amanda; Bresee, Joseph; Abelin, Atika; Boutet, Philippe; Christiansen, Hans; Etholm, Per; Desai, Samir; Gellin, Bruce; Golding, Josephine; Jit, Mark; Kerr, Lawrence; McKinlay, Mark; Kluglein, Samantha; Lobos, Fernando; Mathewson, Sophie; Mazur, Marie; Pagliusi, Sonia; Penttinen, Pasi; Richardson, Dominique; Alvarez, Alba Maria Ropero; Scovitch, Joseph R.; Seedorff, Jennifer E.; Shaxson, Louise; Tam, John S.; Taylor, Beverly; Wairagkar, Niteen; Watson, John; Xeuatvongsa, Anonh
Source:
Vaccine 2020 v.38 no.16 pp. 3179-3183
ISSN:
0264-410X
Subject:
disease severity,   etc   ; burden of disease; economic impact; experts; influenza; influenza vaccines; infrastructure; international organizations; pandemic; public health; stakeholders; vaccination; vaccine development;     Show all 13 Subjects
Abstract:
... In March 2019, a group of global health leaders with expertise in influenza, vaccinology and pandemic preparedness was convened for a meeting titled “Shaping Meeting to explore the value of a coordinated work plan for epidemic and pandemic influenza vaccine preparedness.” Influenza epidemics occur annually in every country in the world, resulting in significant global burden of illness and deaths. ...
DOI:
10.1016/j.vaccine.2020.02.038