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1. A dual-stimulation strategy in a micro-chip for the investigation of mechanical associative learning behavior of C. elegans

Author:
Wang, Yu; Wang, Xixian; Ge, Anle; Hu, Liang; Du, Wei; Liu, Bi-Feng
Source:
Talanta 2020 v.215 pp. 120900
ISSN:
0039-9140
Subject:
dopamine,   etc   ; genes; models; mutants; neurotransmitters; quantitative analysis;     Show all 6 Subjects
Abstract:
... During the past decades, few micro-devices for analysis of associative learning behavior have been reported. In this work, an agarose-PDMS hybridized micro-chip was developed to establish a new associative learning model between mechanosensation and food reward in C. elegans. The micro-chip consisted of column arrays which mimicked mechanical stimulation to C. elegans. After trained by pairing bac ...
DOI:
10.1016/j.talanta.2020.120900

2. Polydopamine as a stable and functional nanomaterial

Author:
El Yakhlifi, Salima; Ball, Vincent
Source:
Colloids and surfaces 2020 v.186 pp. 110719
ISSN:
0927-7765
Subject:
dopamine,   etc   ; coatings; mussels; nanoparticles; nanotubes; oxidants; oxidation;     Show all 7 Subjects
Abstract:
... The mussel inspired chemistry of dopamine leading to versatile coatings on the surface of all kinds of materials in a one pot process was considered as the unique aspect of catecholamine for a long time. Only recently, research has been undertaken to valorize the simultaneous oxidation and colloid formation in dopamine solutions in the presence of an oxidant. This mini review summarizes the synthe ...
DOI:
10.1016/j.colsurfb.2019.110719

3. Zwitterionic polymer chain-assisted lysozyme imprinted core-shell carbon microspheres with enhanced recognition and selectivity

Author:
Qian, Liwei; Liu, Wenqian; Yang, Miaoxiu; Nica, Valentin; Yang, Jinfan; Liu, Hanbin; Ning, Lulu; Zhang, Sufeng; Zhang, Qiuyu
Source:
Talanta 2020 v.217 pp. 121085
ISSN:
0039-9140
Subject:
dopamine,   etc   ; adsorption; carbon; lysozyme; microparticles; polymers; proteins; zwitterions;     Show all 8 Subjects
Abstract:
... Constructing imprinting materials with high recognition and selectivity for protein is an always challenge in protein imprinting technology (PIT). In this work, upon the participating of a zwitterionic polymer chain (Poly (1-vinyl-3-sulfopropylimidazolium), PVSP), a lysozyme imprinted core-shell carbon microsphere (CFC-PVSP@MIPs) was prepared by combining template immobilization method and surface ...
DOI:
10.1016/j.talanta.2020.121085

4. Combining the lack of chromogranins with chronic L-DOPA treatment affects motor activity in mice

Author:
Castañeyra-Ruiz, Leandro; Castañeyra, Agustín; González-Santana, Ayoze; Machado, José D.; Borges, Ricardo
Source:
Cell and tissue research 2020 v.380 no.1 pp. 59-66
ISSN:
0302-766X
Subject:
dopamine,   etc   ; L-dopa; Parkinson disease; mice; oral administration; toxicity;     Show all 6 Subjects
Abstract:
... We have tested whether the lack of chromogranins (Cgs) A and B could provoke CNS disorders when combined with an excess of dopamine. We chronically treated (over 6 months) mice lacking both chromogranins A and B (Cgs-KO) with a low oral dosage of L-DOPA/benserazide (10/2.5 mg/kg). Motor performance in the rota-rod test, open field activity, and metabolic cages indicated a progressive impairment in ...
DOI:
10.1007/s00441-019-03159-8

5. Fast Polymerization of Polydopamine Based on Titanium Dioxide for High-Performance Flexible Electrodes

Author:
Huang, Zhaoling; Zeng, Qi; Hui, Yun; Alahi, Md. Eshrat E.; Qin, Shuijie; Wu, Tianzhun
Source:
ACS applied materials & interfaces 2020 v.12 no.12 pp. 14495-14506
ISSN:
1944-8252
Subject:
dopamine,   etc   ; electric current; electrodes; nanowires; photooxidation; platinum; polymerization; titanium dioxide;     Show all 8 Subjects
Abstract:
... Dopamine (DA) and its derivatives are promising for the fabrication of functional films and devices with excellent conductivity and long-term stability; nevertheless its polymerization process is typically prolonged. We have proposed the accelerated deposition process using ultraviolet (UV) irradiation with the existence of nanotitanium dioxide (nano-TiO₂) in order to realize the rapid and stable ...
DOI:
10.1021/acsami.9b19875

6. Customized unique core-shell Fe2N@N-doped carbon with tunable void space for microwave response

Author:
Cui, Xiaoqing; Liang, Xiaohui; Chen, Jiabin; Gu, Weihua; Ji, Guangbin; Du, Youwei
Source:
Carbon 2020 v.156 pp. 49-57
ISSN:
0008-6223
Subject:
dopamine,   etc   ; carbon; chelation; metal ions; moieties; nanocomposites; nanoparticles; polymerization; shrinkage;     Show all 9 Subjects
Abstract:
... Here, we report a unique core-shell nanocomposite of Fe₂N@N-doped carbon that coats dopamine-derived carbon shells on porous Fe₂N nanoparticles via a facile and effective soft chemical method. The feasibility of preparing core-shell structure in the process of polymerization is realized by utilizing the fact that affluent amino and hydroxyl groups in dopamine endow the formidable chelation ability ...
DOI:
10.1016/j.carbon.2019.09.041

7. A novel approach to study markers of dopamine signaling in peripheral immune cells

Author:
Gopinath, Adithya; Doty, Andria; Mackie, Phillip M.; Hashimi, Basil; Francis, Madison; Saadatpour, Leila; Saha, Kaustuv; Shaw, Gerry; Ramirez-Zamora, Adolfo; Okun, Michael S.; Streit, Wolfgang J.; Khoshbouei, Habibeh
Source:
Journal of immunological methods 2020 v.476 pp. 112686
ISSN:
0022-1759
Subject:
dopamine; dopamine receptors,   etc   ; biomedical research; cryopreservation; flow cytometry; humans; immunohistochemistry; medicine; monocytes; physicochemical properties; therapeutics; tyrosine 3-monooxygenase;     Show all 12 Subjects
Abstract:
... Human monocytes express known markers of dopamine synthesis, storage and clearance, including dopamine transporter (DAT), tyrosine hydroxylase (TH), all subtypes of dopamine receptors and vesicular monoamine transporter 2 (VMAT2). Immunohistochemical and immunofluorescent methodologies have traditionally been employed to determine DAT and TH expression in the CNS, their detection in the blood and ...
DOI:
10.1016/j.jim.2019.112686
PubMed:
31634479
PubMed Central:
PMC6939127

8. Dopamine receptor manipulation does not alter patterns of partner preference in long-term marmoset pairs

Author:
Carp, Sarah B.; Taylor, Jack H.; French, Jeffrey A.
Source:
Physiology & behavior 2019 v.204 pp. 290-296
ISSN:
0031-9384
Subject:
dopamine; dopamine receptors,   etc   ; Callitrichidae; animal models; monkeys; monogamy; neurotransmitters;     Show all 7 Subjects
Abstract:
... The relationship between socially monogamous mates is dynamic and regulated by neurobiological influences. Research in rodent models has indicated a key role for the neurotransmitter dopamine (DA) and its receptors (DAR) in mediating the formation and maintenance of monogamous bonds. DAR activation was pharmacologically manipulated in marmosets housed in long-term pairs. Marmosets exposed to DAR m ...
DOI:
10.1016/j.physbeh.2019.03.004
PubMed:
30853621
PubMed Central:
PMC6475494

9. Microwave absorption enhancement by adjusting reactant ratios and filler contents based on 1D K–MnO₂@PDA and poly(vinylidene fluoride) matrix

Author:
Lv, Shu-Qing; Xu, Wei; Huang, Wujisiguleng; Lv, Guo-Cheng; Wang, Guang-Sheng
Source:
RSC advances 2019 v.9 no.23 pp. 13088-13095
ISSN:
2046-2069
Subject:
dopamine,   etc   ; absorption; nanorods; permeability; thermoplastics;     Show all 5 Subjects
Abstract:
... One-dimensional K–MnO₂ nanorods were prepared by a wet chemical process. Dopamine hydrochloride (PDA) layers with various thicknesses were coated and finally, the composites were filled in a poly(vinylidene fluoride) (PVDF) matrix using the hot-molding procedure. The complex permittivity and permeability of the K–MnO₂@PDA/PVDF composites could be adjusted by reactant amount ratios and filler conte ...
DOI:
10.1039/c9ra01248f

10. Direct Evidence for the Critical Role of 5,6-Dihydroxyindole in Polydopamine Deposition and Aggregation

Author:
Lyu, Qinghua; Hsueh, Nathanael; Chai, Christina L. L.
Source:
Langmuir 2019 v.35 no.15 pp. 5191-5201
ISSN:
1520-5827
Subject:
dopamine,   etc   ; catechol; coatings; copolymerization; moieties;     Show all 5 Subjects
Abstract:
... The definitive role of the intermediate 5,6-dihydroxyindole (DHI) in the formation of polydopamine (PDA) coatings from aqueous dopamine (DA) has not been clearly elucidated and remains highly controversial. Our foray into this debate as reported in this study agrees with some reported assertions that DHI-based coatings are not synonymous with PDA coatings. Our conclusion arises from a systematic c ...
DOI:
10.1021/acs.langmuir.9b00392

11. Exposure to low-dose nanopolystyrene induces the response of neuronal JNK MAPK signaling pathway in nematode Caenorhabditis elegans

Author:
Qu, Man; Li, Dan; Zhao, Yunli; Yuan, Yujie; Wang, Dayong
Source:
Environmental sciences Europe 2020 v.32 no.1 pp. 58
ISSN:
2190-4707
Subject:
dopamine; dopamine receptors,   etc   ; Caenorhabditis elegans; RNA interference; gene expression; genes; intestines; mitogen-activated protein kinase; nanoplastics; neurons; neurotransmitters; octopamine; polystyrenes; signal transduction; toxicity;     Show all 15 Subjects
Abstract:
... BACKGROUND: The response of organisms to nanoplastic exposure has gradually received the attention. Nevertheless, the role of neurons in response to nanoplastic exposure and the underlying mechanism are still largely unclear. We here examined the role of neuronal JNK MAPK signaling in response to low-dose of polystyrene (100 nm) in Caenorhabditis elegans. RESULTS: Exposure to nanopolystyrene in th ...
DOI:
10.1186/s12302-020-00331-8

12. Bromophenols from Symphyocladia latiuscula Target Human Monoamine Oxidase and Dopaminergic Receptors for the Management of Neurodegenerative Diseases

Author:
Paudel, Pradeep; Park, Se Eun; Seong, Su Hui; Jung, Hyun Ah; Choi, Jae Sue
Source:
Journal of agricultural and food chemistry 2020 v.68 no.8 pp. 2426-2436
ISSN:
1520-5118
Subject:
dopamine; dopamine receptors,   etc   ; Parkinson disease; Symphyocladia latiuscula; agonists; alcohols; amine oxidase (flavin-containing); digital images; enzyme inhibitors; humans; ligands; median effective concentration; methyl ethers; neurons; neuroprotective effect; schizophrenia;     Show all 16 Subjects
Abstract:
... Progressive degeneration of dopaminergic neurons in the substantia nigra is the characteristic feature of Parkinson’s disease (PD) and the severity accelerates with aging. Therefore, improving dopamine level or dopamine receptor signaling is a standard approach for PD treatment. Herein, our results demonstrate that bromophenols 2,3,6-tribromo-4,5-dihydroxybenzyl alcohol (1), 2,3,6-tribromo-4,5-dih ...
DOI:
10.1021/acs.jafc.0c00007

13. Daily variation of D2 dopamine receptor transcription in the brain of the Japanese eel Anguilla japonica and its regulation with dopamine and melatonin

Author:
Byun, Jun-Hwan; Hyeon, Ji-Yeon; Kim, Eun-Su; Kim, Shin-Kwon; Hur, Sung-Pyo; Kim, Se-Jae; Takemura, Akihiro
Source:
Comparative biochemistry and physiology 2020 v.240 pp. 110581
ISSN:
1095-6433
Subject:
dopamine; dopamine receptors,   etc   ; Anguilla japonica; amino acids; animal reproduction; antagonists; brain; complementary DNA; eel; gene expression regulation; hormone secretion; hormones; intraperitoneal injection; melatonin; open reading frames; phylogeny; tissues;     Show all 17 Subjects
Abstract:
... Dopamine plays a crucial role in controlling reproduction in eels, and its action is mediated through D2-type dopamine receptors. D2A and D2B receptors in the Japanese eel Anguilla japonica were cloned and characterized in the present study. Attention (daily expression patterns in the brain and endogenous regulation) was paid to D2B receptor because it is considered to play a crucial role in eel r ...
DOI:
10.1016/j.cbpa.2019.110581

14. Identification of a dopamine receptor in Sinonovacula constricta and its antioxidant responses

Author:
Niu, Donghong; Li, Zhi; Du, Yunchao; He, Shengyao; Dong, Zhiguo; Li, Jiale
Source:
Developmental and comparative immunology 2020 v.103 pp. 103512
ISSN:
0145-305X
Subject:
dopamine; dopamine receptors,   etc   ; Veneroida; Vibrio anguillarum; adults; antioxidant activity; catalase; clams; enzyme activity; genes; glycosylation; hydrophobicity; immune response; immune system; liver; phosphorylation; shellfish; superoxide dismutase; tissues; vertebrates;     Show all 20 Subjects
Abstract:
... The dopamine (DA) D2 receptor is a member of the G protein-coupled receptors of organisms and plays an important role in immune system regulation. The presence of DA receptors has been widely reported in vertebrates, but few studies have been conducted in shellfish. Here, we identified a novel DA-D2 receptor gene, ScDopR2-1, in the razor clam Sinonovacula constricta. ScDopR2-1 belongs to the famil ...
DOI:
10.1016/j.dci.2019.103512

15. Effects of dopamine on immune signaling pathway factors, phagocytosis and exocytosis in hemocytes of Litopenaeus vannamei

Author:
Tong, Ruixue; Wei, Cun; Pan, Luqing; Zhang, Xin
Source:
Developmental and comparative immunology 2020 v.102
ISSN:
0145-305X
Subject:
dopamine; dopamine receptors,   etc   ; Crassulacean acid metabolism; G-proteins; Litopenaeus vannamei; exocytosis; gene expression; genes; hemocytes; immune response; ligases; messenger RNA; neurotransmitters; phagocytosis; protein kinases; second messengers; transcription factors;     Show all 17 Subjects
Abstract:
... Dopamine (DA) is an important neuroendocrine factor, which can act as neurotransmitter and neurohormone. In this study, we explored the immune defense mechanism in Litopenaeus vannamei with injection of dopamine at 10−7 and 10−6 mol shrimp−1, respectively. The genes expressions of dopamine receptor (DAR), G proteins (Gs, Gi, Gq), phagocytosis and exocytosis-related proteins, as well as intracellul ...
DOI:
10.1016/j.dci.2019.103473

16. Controllable fabrication of pico/femtoliter pipette sampling probes and visual sample volume determination

Author:
Shao, Yunlong; Zhou, Yingyan; Wu, Yuanyuan; Zhang, Qi; Yu, Zhihui; Guo, Guangsheng; Wang, Xiayan
Source:
Talanta 2020 v.218 pp. 121096
ISSN:
0039-9140
Subject:
dopamine,   etc   ; Portulaca oleracea; electroosmosis; image analysis; liquids; mass spectrometry; metabolites; petioles; standard deviation;     Show all 9 Subjects
Abstract:
... We propose a hydraulically assisted eddy-current etching method for the controllable fabrication of pico/femtoliter sampling probes with equal inner diameters along the length of the probe. The relative standard deviations of the outer and inner diameters (O.D. and I.D., respectively) of several 1.07-μm-I.D. sampling probe tips fabricated in a single batch using this method were 2.2% and 2.8%, res ...
DOI:
10.1016/j.talanta.2020.121096

17. γ-Aminobutyric acid transporters as relevant biological target: Their function, structure, inhibitors and role in the therapy of different diseases

Author:
Łątka, Kamil; Jończyk, Jakub; Bajda, Marek
Source:
International journal of biological macromolecules 2020 v.158 pp. 750-772
ISSN:
0141-8130
Subject:
dopamine,   etc   ; cell membranes; gamma-aminobutyric acid; leucine; mutagenesis; nervous system; neurotransmitters; sequence analysis; serotonin; therapeutics; transporters;     Show all 11 Subjects
Abstract:
... γ-Aminobutyric acid (GABA) is a major inhibitory neurotransmitter in the nervous system. It plays a crucial role in many physiological processes. Upon release from the presynaptic element, it is removed from the synaptic cleft by reuptake due to the action of GABA transporters (GATs). GATs belong to a large SLC6 protein family whose characteristic feature is sodium-dependent relocation of neurotra ...
DOI:
10.1016/j.ijbiomac.2020.04.126

18. Fluorometric detection of dopamine based on 3-aminophenylboronic acid-functionalized AgInZnS QDs and cells imaging

Author:
Liu, Yibing; He, Xu; Ma, Pinyi; Huang, Yibing; Li, Xiaolei; Sun, Ying; Wang, Xinghua; Song, Daqian
Source:
Talanta 2020 v.217 pp. 121081
ISSN:
0039-9140
Subject:
dopamine,   etc   ; biocompatibility; boronic acids; brain; cysteine; detection limit; fluorescence; fluorometry; image analysis; lysosomes; neurotransmitters;     Show all 11 Subjects
Abstract:
... Herein, cysteine capped AgInZnS QDs (Cys-AIZS QDs) with a large stoke shift and excellent biocompatibility were synthesized by a one-step aqueous method, followed by modified with 3-aminophenylboronic acid (APBA). Dopamine (DA) as an important neurotransmitter in brain can lead to significantly decrease in the fluorescence intensity of 3-aminophenylboronic acid-functionalized Cys-AIZS QDs (APBA-AI ...
DOI:
10.1016/j.talanta.2020.121081

19. Blue and green emission-transformed fluorescent copolymer: Specific detection of levodopa of anti-Parkinson drug in human serum

Author:
Chen, Can; Zou, Changpeng; Li, Lin; Yu, Haidong; Zhu, Jixin; Liu, Jinhua; Huang, Wei
Source:
Talanta 2020 v.214 pp. 120817
ISSN:
0039-9140
Subject:
dopamine,   etc   ; L-dopa; Parkinson disease; blood serum; composite polymers; detection limit; drugs; fluorescence; humans; monitoring;     Show all 10 Subjects
Abstract:
... Levodopa, commonly used anti-Parkinson drugs in the clinic, is the most significant prodrug of dopamine that plays important roles in the treatment of Parkinson's disease. Therefore, monitoring content of levodopa of anti-parkinson drugs in human serum is extremely necessary. Herein, a simple, fast and low-cost method for levodopa detection is proposed depending on the in situ formation of blue an ...
DOI:
10.1016/j.talanta.2020.120817

20. Preparation of BSA surface imprinted manganese dioxide-loaded tubular carbon fibers with excellent specific rebinding to target protein

Author:
Yang, Zuoting; Chen, Junjie; Yang, Ke; Zhang, Qiuyu; Zhang, Baoliang
Source:
Journal of colloid and interface science 2020 v.570 pp. 182-196
ISSN:
0021-9797
Subject:
dopamine,   etc   ; adsorption; bovine serum albumin; carbon fibers; fetal bovine serum; manganese dioxide; nanosheets; polymers;     Show all 8 Subjects
Abstract:
... Along with the wide development of protein imprinted polymers, the researchers still face many challenges, such as difficult template elution, slow adsorption rate and low adsorption capacity. In order to promote the progress of protein separation and purification, the surface imprinted manganese dioxide-loaded tubular carbon fibers (FTCFs@MnO₂@MIPs) are prepared in this work. FTCFs@MnO₂@MIPs are ...
DOI:
10.1016/j.jcis.2020.02.119