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1. A review on the traditional uses, phytochemistry, and pharmacology of the genus Veronicastrum (Plantaginaceae)

Author:
Elizabeth Syowai Mutinda; Elijah Mbandi Mkala; Jing Ren; Festus Kimutai; Emmanuel Nyongesa Waswa; Wyclif Ochieng Odago; Consolata Nanjala; Moses Kirega Gichua; Moses Muguci Njire; Guang-Wan Hu
Source:
Journal of ethnopharmacology 2023 v.300 pp. 115695
ISSN:
0378-8741
Subject:
edema,   etc   ; Plantaginaceae; analgesia; antimicrobial properties; antioxidants; ascites; blood stasis; cough; drugs; dysentery; fever; flavonoids; flora; headache; immunosuppression; iridoids; liver; mechanism of action; nephritis; pharmacology; phytosterols; rheumatoid arthritis; traditional medicine; China;     Show all 24 Subjects
Abstract:
... Veronicastrum Heist. ex Fabr. (Plantaginaceae) is a multifunctional plant in China and other parts of the continent. It has traditionally been used in the treatment of ascites, edema, blood stasis, pain relief, chronic nephritis injury, fever, cough, headache, arthritis, dysentery, rheumatism, pleural effusion, liver damage, and other disorders. Although research has confirmed that the genus Veron ...
DOI:
10.1016/j.jep.2022.115695

2. 23-O-acetylshengmanol-3-O-α-L-arabinoside alleviates lipopolysaccharide-induced acute lung injury through inhibiting IκB/NF-κB and MAPK/AP-1 signaling pathways

Author:
Chunyan Chen; Lin Li; Xiaomei Liu; Deqin Zhang; Yang Liu; Yuhong Li
Source:
Journal of ethnopharmacology 2023 v.300 pp. 115725
ISSN:
0378-8741
Subject:
edema,   etc   ; Actaea cimicifuga; Oriental traditional medicine; Western blotting; blood serum; cytotoxicity; enzyme-linked immunosorbent assay; eosin; fluorescent antibody technique; genes; glycosides; histopathology; interleukin-6; lipopolysaccharides; lung function; lungs; macrophages; models; nitric oxide; pharyngitis; phosphorylation; plethysmography; protein content; rhizomes; therapeutics; toxicity testing; triterpenoids;     Show all 27 Subjects
Abstract:
... Cimicifuga foetida L. is a well-established traditional Chinese medicine with heat-clearing and detoxifying effects and has good therapeutic effect on oral mucosal ulcer and pharyngitis. The rhizome of this herb is rich in triterpenoid glycosides, including 23-O-acetylshengmanol-3-o-α-L-arabinoside (DA). Whether and how DA attenuates acute lung injury (ALI) are unclear. Accordingly, we focused on ...
DOI:
10.1016/j.jep.2022.115725

3. Analgesic, anti-inflammatory activity and metabolite profiling of the methanolic extract of Callicarpa arborea Roxb. leaves

Author:
Rubaet Sharmin Ema; S.M. Neamul Kabir Zihad; Md Naharul Islam; Nazifa Sifat; Razina Rouf; Jamil A. Shilpi; Shaikh Jamal Uddin
Source:
Journal of ethnopharmacology 2023 v.300 pp. 115757
ISSN:
0378-8741
Subject:
edema,   etc   ; Callicarpa; acetic acid; acute toxicity; albino; analgesic effect; analgesics; anti-inflammatory activity; chemical composition; dose response; egg albumen; formalin test; gas chromatography-mass spectrometry; hot plate test; metabolites; mortality; pain; phytochemicals; rheumatoid arthritis; toxicity testing; traditional medicine; tribal peoples; Bangladesh; India;     Show all 24 Subjects
Abstract:
... Callicarpa arborea Roxb. is widely used as traditional medicine especially by the tribal people of Bangladesh in the management of wide range of ailments. In addition to Bangladesh, the leaves of this plant is utilized as a remedy to various painful and inflammatory conditions including rheumatism, toothache and stomachache in other countries of Indian subcontinent. Depending on the ethnomedicinal ...
DOI:
10.1016/j.jep.2022.115757

4. Protease inhibitor from Libidibia ferrea seeds attenuates inflammatory and nociceptive responses in mice

Author:
Raquel Carvalho; Iluska Senna Bonfá; Jéssica de Araújo Isaías Muller; Silvana Cristina Pando; Mônica Cristina Toffoli-Kadri
Source:
Journal of ethnopharmacology 2023 v.300 pp. 115694
ISSN:
0378-8741
Subject:
edema,   etc   ; Caesalpinia ferrea; acetic acid; adhesion; analgesic effect; anti-inflammatory activity; asthma; bark; bronchitis; cell adhesion; cytokines; cytotoxicity; enterocolitis; fever; formalin; formalin test; fruits; hydrogen peroxide; leukocytes; macrophages; males; mast cells; nitric oxide; pain; permeability; pharyngitis; proteinase inhibitors; proteinases; rheumatoid arthritis; traditional medicine; trees;     Show all 31 Subjects
Abstract:
... Libidibia ferrea (Mart. ex. Tul.) L.P. Queiroz is a Brazilian native tree locally known as jucá and pau-ferro, and it has been used in folk medicine for relieving, asthma, bronchitis, sore throat, rheumatism, enterocolitis and fever. The anti-inflammatory properties of L. ferrea were confirmed for its stem, fruit, leaves, bark and seeds extracts, however little is known about the natural compounds ...
DOI:
10.1016/j.jep.2022.115694

5. Clinical Features and Genetic Findings of Autosomal Recessive Bestrophinopathy

Author:
Hae Rang Kim; Jinu Han; Yong Joon Kim; Hyun Goo Kang; Suk Ho Byeon; Sung Soo Kim; Christopher Seungkyu Lee
Source:
Genes 2022 v.13 no.7 pp. -
ISSN:
2073-4425
Subject:
edema,   etc   ; genes; glaucoma; patients; phenotype;     Show all 5 Subjects
Abstract:
... Autosomal recessive bestrophinopathy (ARB) is a rare subtype of bestrophinopathy caused by biallelic mutations of the BEST1 gene. ARB is characterized by multifocal subretinal deposits accompanied by macular edema or subretinal fluid, hyperopia, co-existing narrow angle, and a marked decrease in electrooculogram. However, little is known about the genetic variants and specific clinical features of ...
DOI:
10.3390/genes13071197

6. Non-cardiogenic pulmonary oedema complicating balloon valvuloplasty and stent angioplasty of severe pulmonary valve stenosis in four dogs

Author:
G. Santarelli; J. Bouvard; S.F. Brethel; S. Gordon; S. Lord; A. Mavropoulou; P. Oliveira; K.T. Sykes; S. Swift; G.J. Culshaw
Source:
Journal of veterinary cardiology 2022 v.39 pp. 79-88
ISSN:
1760-2734
Subject:
edema,   etc   ; disease course; hypertension; morbidity; mortality;     Show all 5 Subjects
Abstract:
... In dogs, balloon valvuloplasty is considered the treatment of choice for severe pulmonary valve stenosis, and this technique is currently performed routinely in specialist referral practices with low morbidity and mortality. Stent angioplasty has also been recently proposed as a viable treatment option. The present case series describes the clinical course of four dogs with severe pulmonary valve ...
DOI:
10.1016/j.jvc.2021.12.003

7. Surgical management of corneal ulcers in dogs: Pedicle and bridge conjunctival grafts

Author:
Gurpreet Singh; Tarunbir Singh; S.K. Mahajan; N.S. Saini; J. Mohindroo; Pallavi Verma
Source:
Indian journal of veterinary surgery 2022 v.43 no.1 pp. 28-34
ISSN:
0973-9726
Subject:
edema,   etc   ; cornea; dehiscence; dogs; pigmentation; surgery; vision;     Show all 7 Subjects
Abstract:
... Corneal ulcers are commonly found eye disorders. If not treated appropriately it can lead to permanent damage to the eye. Routine medicinal treatment many times is not able to achieve healing, which necessitates the surgical intervention. The study was conducted to treat canine corneal ulcer using conjunctival pedicle grafting (group I) and conjunctival bridge grafting (group II) techniques. The s ...
DOI:
10.5958/0973-9726.2022.00008.0

8. High‐field MRI using standard pulse sequences has moderate to substantial interobserver agreement and good accuracy for differentiation between intracranial extra‐axial histiocytic sarcoma and meningioma in dogs

Author:
Wilfried Mai; Emily E. Burke; Jennifer A. Reetz; Silke Hecht; Matthew Paek; Molly E. Church; Stephen R. Werre; Christopher L. Mariani; John F. Griffin; Eric N. Glass
Source:
Veterinary radiology & ultrasound 2022 v.63 no.2 pp. 176-184
ISSN:
1058-8183
Subject:
edema,   etc   ; dogs; magnetism; probability; prognosis; radiology; sarcoma; ultrasonics;     Show all 8 Subjects
Abstract:
... Intracranial extra‐axial histiocytic sarcoma shares common MRI features with meningioma. As histiocytic sarcoma carries a generally worse prognosis than meningioma, the ability to differentiate between these two neoplasms is of clinical value. The aim of this retrospective diagnostic accuracy and observer agreement study was to evaluate the accuracy and reliability of high‐field MRI to differentia ...
DOI:
10.1111/vru.13038

9. Describing and Characterizing the Literature Regarding Umbilical Health in Intensively Raised Cattle: A Scoping Review

Author:
Matthew B. Van Camp; David L. Renaud; Todd F. Duffield; Diego E. Gomez; William J. McFarlane; Joanne Marshall; Charlotte B. Winder
Source:
Veterinary sciences 2022 v.9 no.6 pp. -
ISSN:
2306-7381
Subject:
edema,   etc   ; cattle; myiasis; risk factors; umbilical cord; Brazil; Canada;     Show all 7 Subjects
Abstract:
... The objective of this scoping review was to describe and characterize the existing literature regarding umbilical health and identify gaps in knowledge. Six databases were searched for studies examining umbilical health in an intensively raised cattle population. There were 4249 articles initially identified; from these, 723 full text articles were then screened, with 150 articles included in the ...
DOI:
10.3390/vetsci9060288

10. Relationship of brain edema after deep brain stimulation surgery with motor and cognitive function

Author:
Yamato Nishiguchi; Keita Matsuura; Yoshinori Hirata; Akane Mizutani; Natsuko Katoh; Hidehiro Ishikawa; Koichi Miyashita; Takaya Utsunomiya; Hiroyuki Kajikawa; Hirofumi Nishikawa; Tomohiro Araki; Akihiro Shindo; Hidekazu Tomimoto
Source:
Heliyon 2022 v.8 no.2 pp. e08900
ISSN:
2405-8440
Subject:
edema,   etc   ; Parkinson disease; brain; cognition; cognitive disorders; magnetism; surgery;     Show all 7 Subjects
Abstract:
... Some patients with Parkinson's disease (PD) develop peri-lead brain edema after deep brain stimulation (DBS) surgery. The influence of edema on neurological function is not well characterized. We investigated the relationship of brain edema after DBS surgery with motor and cognitive function. Thirteen patients with PD (6 males and 7 females; mean age: 61.2 years) who underwent bilateral subthalami ...
DOI:
10.1016/j.heliyon.2022.e08900

11. Outcome of superficial brachial axial pattern flaps used to close skin defects in dogs: 16 cases (1996‐2019)

Author:
E. Villedieu; M. C. Nolff; S. Del Magno; T. Emmerson; E. Field; R. Hattersley; B. De La Puerta; R. A. Ragni; S. J. Baines
Source:
journal of small animal practice 2022 v.63 no.2 pp. 136-141
ISSN:
0022-4510
Subject:
edema,   etc   ; dehiscence; necrosis; neoplasms; small animal practice; surgery; wound treatment;     Show all 7 Subjects
Abstract:
... OBJECTIVES: To report the complication rate, type of complications and outcome of the superficial brachial axial pattern flap when used for closure of skin defects in dogs. MATERIALS AND METHODS: Medical records of dogs treated with a superficial brachial axial pattern flap for closure of a skin defect were reviewed. Information regarding signalment, reason for axial pattern flap use, skin flap si ...
DOI:
10.1111/jsap.13435

12. A scenario for the origin of life: Volume regulation by bacteriorhodopsin required extremely voltage sensitive Na‐channels and very selective K‐channels

Author:
David Naranjo
Source:
BioEssays 2022 v.44 no.10 pp. e2100210
ISSN:
0265-9247
Subject:
edema,   etc   ; cell physiology; electric potential difference; extremophiles; metabolites; neurons; pH;     Show all 7 Subjects
Abstract:
... The osmotic activity produced by internal, non‐permeable, anionic nucleic acids and metabolites causes a persistent and life‐threatening cell swelling, or cellular edema, produced by the Gibbs‐Donnan effect. This evolutionary‐critical osmotic challenge must have been resolved by LUCA or its ancestors, but we lack a cell‐physiology look into the biophysical constraints to the solutions. Like mycopl ...
DOI:
10.1002/bies.202100210

13. Vascular Tumors in Two Argentine Horned Frogs (Ceratophrys ornata)

Author:
Mitsuhiro Ikeda; Hirotaka Kondo; Yuki Iwata; Iori Koizumi; Naoto Tsunesumi; Hisashi Shibuya
Source:
Journal of herpetological medicine and surgery 2022 v.32 no.2 pp. 119-122
ISSN:
1529-9651
Subject:
edema,   etc   ; antibodies; blood; blood vessels; frogs; hemangiosarcoma; immunohistochemistry; medicine; surgery;     Show all 9 Subjects
Abstract:
... Two vascular tumors in two Argentine horned frogs (Ceratophrys ornata) are described. Case 1 involved a 7-yr-1-month-old Argentine horned frog that had a splenic mass with a sanguineous coelomic effusion. Histologically, the splenic parenchyma was effaced by a poorly demarcated, invasive mass consisting of spindle cells with marked nuclear atypia forming irregular blood vessel channels containing ...
DOI:
10.5818/JHMS-D-21-00034

14. Detection of fenoldopam-induced arteritis in rats using ex vivo / in vivo MRI

Author:
Yuta Fujii; Yuka Yoshino; Kazuhiro Chihara; Aya Nakae; Jun-ichiro Enmi; Yoshichika Yoshioka; Izuru Miyawaki
Source:
Toxicology reports 2022 v.9 pp. 1595-1602
ISSN:
2214-7500
Subject:
edema,   etc   ; agonists; arteritis; biomarkers; dopamine; erythrocytes; euthanasia; histopathology; magnetism; rats; toxicology;     Show all 11 Subjects
Abstract:
... A method capable of identifying drug-induced arteritis is highly desirable because no specific and sensitive biomarkers have yet been defined. Although magnetic resonance imaging (MRI) may be used to find a biomarker candidate for drug-induced arteritis, there are no reports on the evaluation of drug-induced arteritis by MRI. The present study was conducted to clarify whether Fenoldopam mesylate ( ...
DOI:
10.1016/j.toxrep.2022.07.012

15. CYP2S1 gene methylation among High-altitude pulmonary edema

Author:
Tianbo Jin; Hongyan Lu; Zhanhao Zhang; Yuliang Wang; Wei Yang; Yuhe Wang; Xue He; Dongya Yuan; Yongjun He
Source:
Gene 2022 v.834 pp. 146590
ISSN:
0378-1119
Subject:
edema,   etc   ; DNA methylation; acute exposure; altitude; genes; hypoxia; probability analysis; risk;     Show all 8 Subjects
Abstract:
... High altitude pulmonary edema (HAPE) is a fatal disease of fluid accumulation in the lungs resulting from acute exposure to high altitude and hypoxia. Now research has found that changes in DNA methylation are genetically related. We investigated the effects of hypermethylation and hypomethylation on HAPE. We conducted an analysis of methylation in Chinese HAPE patients (53 patients and 53 control ...
DOI:
10.1016/j.gene.2022.146590

16. Phenotypic and Genetic Characteristics in a Cohort of Patients with Usher Genes

Author:
Helena M. Feenstra; Saoud Al-Khuzaei; Mital Shah; Suzanne Broadgate; Morag Shanks; Archith Kamath; Jing Yu; Jasleen K. Jolly; Robert E. MacLaren; Penny Clouston; Stephanie Halford; Susan M. Downes
Source:
Genes 2022 v.13 no.8 pp. -
ISSN:
2073-4425
Subject:
edema,   etc   ; genes; genotype; genotype-phenotype correlation; phenotype; prognosis; retinitis pigmentosa; tomography;     Show all 8 Subjects
Abstract:
... Background: This study aimed to compare phenotype–genotype correlation in patients with Usher syndrome (USH) to those with autosomal recessive retinitis pigmentosa (NS-ARRP) caused by genes associated with Usher syndrome. Methods: Case notes of patients with USH or NS-ARRP and a molecularly confirmed diagnosis in genes associated with Usher syndrome were reviewed. Phenotypic information, including ...
DOI:
10.3390/genes13081423

17. Defining Wound Healing Progression in Cetacean Skin: Characteristics of Full-Thickness Wound Healing in Fraser’s Dolphins (Lagenodelphis hosei)

Author:
Chen-Yi Su; Michael W. Hughes; Tzu-Yu Liu; Cheng-Ming Chuong; Hao-Ven Wang; Wei-Cheng Yang
Source:
Animals 2022 v.12 no.5 pp. -
ISSN:
2076-2615
Subject:
edema,   etc   ; Cetacea; Isistius; blubber; collagen; dolphins; histopathology; humans; medicine; melanin; melanocytes; sharks;     Show all 12 Subjects
Abstract:
... Cetaceans are tight-skinned mammals that exhibit an extraordinary capacity to heal deep soft tissue injuries. However, essential information of large full-thickness wound healing in cetaceans is still lacking. Here, the stages of full-thickness wound healing were characterized in Fraser’s dolphins (Lagenodelphis hosei). The skin samples were collected from normal skin and full-thickness cookiecutt ...
DOI:
10.3390/ani12050537

18. Ginger Is a Potential Therapeutic for Chronic Toxoplasmosis

Author:
Asmaa M. El-kady; Wafa Abdullah I. Al-Megrin; Iman A. M. Abdel-Rahman; Eman Sayed; Eman Abdullah Alshehri; Majed H. Wakid; Fadi M. Baakdah; Khalil Mohamed; Hayam Elshazly; Hussah M. Alobaid; Safa H. Qahl; Hatem A. Elshabrawy; Salwa S. Younis
Source:
Pathogens 2022 v.11 no.7 pp. -
ISSN:
2076-0817
Subject:
edema,   etc   ; albino; apoptosis; ginger; hepatocytes; inflammation; liver; neurons; parasites; spiramycin; therapeutics; toxoplasmosis;     Show all 12 Subjects
Abstract:
... Background:Toxoplasma gondii (T. gondii) is an opportunistic parasite that causes serious diseases in humans, particularly immunocompromised individuals and pregnant women. To date, there are limited numbers of therapeutics for chronic toxoplasmosis which necessitate the discovery of effective and safe therapeutics. In the present study, we aimed to evaluate the antitoxoplasmosis potential of ging ...
DOI:
10.3390/pathogens11070798

19. Hormonal Management for the Induction of Luteolysis and Ovulation in Andalusian Jennies: Effect on Reproductive Performance, Embryo Quality and Recovery Rate

Author:
Marina Bottrel; Isabel Ortiz; Manuel Hidalgo; María Díaz-Jiménez; Blasa Pereira; César Consuegra; Mohamed Samy Yousef; Jesús Dorado
Source:
Animals 2022 v.12 no.2 pp. -
ISSN:
2076-2615
Subject:
edema,   etc   ; deslorelin acetate; estrus; human chorionic gonadotropin; luteolysis; ovulation; prostaglandins; reproductive performance;     Show all 8 Subjects
Abstract:
... Two prostanglandins (luprostiol, LUP, and dinoprost, DIN) and two ovulation-inducing agents (human Chorionic Gonadotropin, hCG, and deslorelin, DES) were evaluated for luteolysis and estrus induction, and for ovulation induction, respectively, in embryo donor jennies. Twenty-six fertile Andalusian jennies were used. In Experiment 1, jennies (n = 112 cycles) were randomly treated with either LUP or ...
DOI:
10.3390/ani12020143

20. Next Generation Sequencing after Invasive Prenatal Testing in Fetuses with Congenital Malformations: Prenatal or Neonatal Investigation

Author:
Alexandra Emms; James Castleman; Stephanie Allen; Denise Williams; Esther Kinning; Mark Kilby
Source:
Genes 2022 v.13 no.9 pp. -
ISSN:
2073-4425
Subject:
edema,   etc   ; aneuploidy; cohort studies; etiology; genome; heart diseases; karyotyping; microarray technology; ultrasonics;     Show all 9 Subjects
Abstract:
... Congenital malformations diagnosed by ultrasound screening complicate 3–5% of pregnancies and many of these have an underlying genetic cause. Approximately 40% of prenatally diagnosed fetal malformations are associated with aneuploidy or copy number variants, detected by conventional karyotyping, QF-PCR and microarray techniques, however monogenic disorders are not diagnosed by these tests. Next g ...
DOI:
10.3390/genes13091517