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epithelium, etc ; Internet; humans; inflammation; microRNA; models; oxidative stress; particulates; synergism; China; Show all 10 Subjects
Abstract:
... Inflammation is a major adverse outcome induced by inhaled particulate matter with a diameter of ≤ 2.5 µm (PM₂.₅), and a critical trigger of most PM₂.₅ exposure-associated diseases. However, the key molecular events regulating the PM₂.₅-induced airway inflammation are yet to be elucidated. Considering the critical role of circular RNAs (circRNAs) in regulating inflammation, we predicted 11 circRNA ...
... Intraocular angiogenesis mediated by vascular endothelial growth factor (VEGF) and the related ocular disease, age-related macular degeneration (AMD), is the leading cause of loss of vision worldwide. Though anti-VEGF antibodies are used to control AMD, administration of high doses or frequent dosing, and poor ocular retention of the drug adversely affect the patient outcomes. Herein, we report th ...
epithelium, etc ; Influenza A virus; Oriental traditional medicine; Trollius chinensis; Western blotting; blood; cytoplasm; fluorescent antibody technique; lungs; nasal cavity; pharmacology; pharyngitis; pneumonia; spleen; therapeutics; viruses; Show all 16 Subjects
Abstract:
... The flowers of Trollius chinensis Bunge (Ranunculaceae) is a traditional Chinese medicine used to treat various inflammatory diseases, including upper respiratory infections, chronic tonsillitis, and pharyngitis. Recently, there has been growing research on the antiviral role of the flowers of T. chinensis Bunge. However, little is known about its anti-influenza virus effects and the underlying me ...
... Insect immunity defends the infection of an insect pathogenic bacterium, Bacillus thuringiensis (Bt). However, it was not clear on the recognition of Bt infection by the insect immune system. This study tested a physiological function of dorsal switch protein 1 (DSP1) in the Bt infection. DSP1 is classified into HMGB1-like damage-associated molecular pattern (DAMP) in insects. Upon Bt infection in ...
epithelium, etc ; antibodies; collagen; environmental exposure; fibroblasts; fibrosis; gelatinase A; glycoproteins; inflammation; interleukin-11; interleukin-6; lungs; mice; mitogen-activated protein kinase; necrosis; neoplasms; neutralization; silica; therapeutics; China; Show all 20 Subjects
Abstract:
... Environmental exposure to crystalline silica particles can lead to silicosis, which is one of the most serious pulmonary interstitial fibrosis around the world. Unfortunately, the exact mechanism on silicosis is unclear, and the effective treatments are lacking to date. In this study, we aim to explore the molecular mechanism by which interleukin-11 (IL-11) affects silica particles-induced lung in ...
... Tungsten trioxide (WO₃)-based nanoparticles (NPs) are gaining popularity because of their exciting potential for photocatalytic applications; however, the toxic potential of WO₃-based NPs remains a concern. In this study, we evaluated the toxic risk of WO₃ NPs and hydrated WO₃ NPs (WO₃·H₂O NPs) using lung cells and explored the underlying mechanism. WO₃ NPs and WO₃·H₂O NPs significantly decreased ...
... This study evaluated the epidermis mucosal capacity of goldfish (Carassius auratus) during different stages of reproductive development in both females and males. In this regard, the activity of mucolytic immune enzymes, i.e., lysozyme, complement and peroxidase, as well as the activity of alkaline phosphatase (ALP) were evaluated. There were five stages for females i.e., immature (f1), cortical a ...
... Selection of the appropriate strain for particular aquatic animals is necessary for the desirable benefits of probiotics application in aquaculture, however, it is not very clear whether fish-derived probiotics could provide beneficial effects on invertebrates. In the present study, two fish-derived probiotics, Bacillus amyloliquefaciens, and Lactococcus lactis, were administrated as feed additive ...
... Understanding how HAI‐1 and HAI‐2 regulate the epithelial serine protease matriptase may hold the key to curing epithelial‐derived cancer. HAIs are serine protease inhibitors that inhibit matriptase and have a poorly understood effect on the presence of matriptase protein in cells. In this issue of The FEBS Journal, Yamashita et al. provide much‐needed new insights into this effect, describing it ...
... Contamination of V. parahaemolyticus in raw product and culture areas of Crassostrea gigas has been a concern in food hygiene and infectious diseases in the shellfish aquaculture industry for decades. Although numerous researchers have presently objective of decreasing pathogen microorganism contaminated load in raw oysters or genetics improvement for prevention, the in-depth information at the mo ...
... Our morphological study of the exocrine system in workers of Leptanilla clypeata revealed the presence of at least 23 glands. Among these, the dorsoproximal intramandibular gland represents a novel structure for social insects. Another novel gland may exist in the ventral part of the postpetiolus; both the petiole and postpetiole contain conspicuous clusters of large gland cells. The occurrence of ...
epithelium, etc ; biochemical compounds; excretion; humans; Show all 4 Subjects
Abstract:
... Bacteria contribute to human host (patho)physiology through the production of a myriad of biomolecules enclosed in membrane vesicles [bacterial extracellular vesicles (BEVs)]. Recent research revealed that BEVs, as a functional output of bacteria, enter the systemic circulation. Here, we highlight the current state of knowledge on the origin, translocation, distribution, function, and excretion or ...
epithelium, etc ; estradiol; guineafowl; histology; oviducts; Show all 5 Subjects
Abstract:
... There are limited data available on the biology of guinea fowls. The objective of this study was to document post-hatch histological and stereological changes in the oviducts of 56 guinea hens and associated 17β-estradiol profiles until 32 weeks of age and to explore changes in the oviducal mucosal fold as an index of oviducal growth. Mucosal folds in all regions of the oviduct increased significa ...
... Thymically-derived Foxp3⁺ regulatory T cells (Tᵣₑg) critically control immunological tolerance. These cells are generated in the medulla through high affinity interactions with medullary thymic epithelial cells (mTEC) expressing the Autoimmune regulator (Aire). Recent advances have revealed that thymic Tᵣₑg contain not only developing but also recirculating cells from the periphery. Although Aire ...
Matteo Cantatore; Juan Carlos Jimeno Sandoval; Smita Das; Alberto Sesana; Tim Charlesworth; Tony Ryan; Emanuela M. Morello; Matteo Gobbetti; Filippo Cinti; Matteo Rossanese
... OBJECTIVE: To report complications and long‐term outcomes after submucosal resections of benign and malignant epithelial rectal masses. STUDY DESIGN: Retrospective multicentric study. SAMPLE POPULATION: Medical records of 93 dogs at 7 referral hospitals. METHODS: Records were reviewed for surgical time, diagnosis, margins, complications, and recurrences. Survival of dogs was evaluated based on tum ...
epithelium, etc ; epithelial cells; olfactory receptors; Show all 3 Subjects
Abstract:
... Neurons and epithelia are viewed as fundamentally different cell types, yet some sensory neurons exhibit hallmarks of epithelial cells. For example, they use tight junctions to form a diffusion barrier continuous with the skin or other epithelia and they exhibit bona fide apical-basal polarity, with an outward-facing apical surface that is biochemically and functionally distinct from their inward- ...
epithelium, etc ; clinical examination; inflammation; veterinary medicine; Show all 4 Subjects
Abstract:
... Wound healing is a complicated process consisting of overlapping phases directed and regulated by many mediators of healing produced locally at the wound. The end goal of wound healing is the production of tissue at the site of injury which has a similar structure and provides protection to the body. Any alterations in the normal healing process can lead to delayed healing or additional tissue dam ...
epithelium, etc ; immunity; microorganisms; uterine cervical neoplasms; Show all 4 Subjects
Abstract:
... The heterogeneity of the cervico-vaginal microbiota can be appreciated in various conditions, both pathological and non-pathological, and can vary according to biological and environmental factors. Attempts are still in course to define the interaction and role of the various factors that constitute this community of commensals in immune protection, inflammatory processes, and the onset of precanc ...
epithelium, etc ; bladder; inflammation; interstitial cystitis; pain; Show all 5 Subjects
Abstract:
... Cystitis is a bladder disease with a high rate of prevalence in the world population. This report focuses on Interstitial Cystitis (IC), Hemorrhagic Cystitis (HC) and Chronic Radiation Cystitis. These pathologies have different etiologies, but they share common symptoms, for instance, pain, bleeding, and a contracted bladder. Overall, treatments are quite similar for abacterial cystitis, and inclu ...
epithelium, etc ; histology; keratinization; morphometry; rats; tongue; Show all 6 Subjects
Abstract:
... The mammalian tongue plays a fundamental role in various physiological and behavioral activities. Significant morphological variations have been recorded in the tongue of several species. This study aims to obtain detailed histological and morphometric information about the filiform papillae on the surface of rat tongue. The tongues of five 10-month-old Wistar rats were utilized, which were later ...