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1. Zn2+ loading as a critical contributor to the circ_0008553-mediated oxidative stress and inflammation in response to PM2.5 exposures

Author:
Jingzhou Wang; Jianbo Jia; Dujia Wang; Xiujiao Pan; Haiyan Xiong; Chengjun Li; Yiguo Jiang; Bing Yan
Source:
Journal of environmental sciences (China) 2023 v.124 pp. 451-461
ISSN:
1001-0742
Subject:
epithelium,   etc   ; Internet; humans; inflammation; microRNA; models; oxidative stress; particulates; synergism; China;     Show all 10 Subjects
Abstract:
... Inflammation is a major adverse outcome induced by inhaled particulate matter with a diameter of ≤ 2.5 µm (PM₂.₅), and a critical trigger of most PM₂.₅ exposure-associated diseases. However, the key molecular events regulating the PM₂.₅-induced airway inflammation are yet to be elucidated. Considering the critical role of circular RNAs (circRNAs) in regulating inflammation, we predicted 11 circRNA ...
DOI:
10.1016/j.jes.2021.11.015

2. Anti-angiogenic carbon nanovesicles loaded with bevacizumab for the treatment of age-related macular degeneration

Author:
Anisha Anand; Hong-Jyuan Jian; Hao-Hsin Huang; Li Er Hean; Yu-Jia Li; Jui-Yang Lai; Hung-Da Chou; Yu-Chuan Kang; Wei-Chi Wu; Chi-Chun Lai; Chih-Ching Huang; Huan-Tsung Chang
Source:
Carbon 2023 v.201 pp. 362-370
ISSN:
0008-6223
Subject:
epithelium,   etc   ; angiogenesis; antibodies; bioavailability; carbon; carbonization; cell proliferation; cost effectiveness; cytotoxicity; drugs; encapsulation; macular degeneration; patients; rabbits; therapeutics; vascular endothelial growth factors; vision;     Show all 17 Subjects
Abstract:
... Intraocular angiogenesis mediated by vascular endothelial growth factor (VEGF) and the related ocular disease, age-related macular degeneration (AMD), is the leading cause of loss of vision worldwide. Though anti-VEGF antibodies are used to control AMD, administration of high doses or frequent dosing, and poor ocular retention of the drug adversely affect the patient outcomes. Herein, we report th ...
DOI:
10.1016/j.carbon.2022.09.045

3. The crude extract from the flowers of Trollius chinensis Bunge exerts anti-influenza virus effects through modulation of the TLR3 signaling pathway

Author:
Yuxi Liang; Xiaoli Liu; Jingyan Hu; Songli Huang; Xin Ma; Xiaoyan Liu; Rufeng Wang; Xiuhua Hu
Source:
Journal of ethnopharmacology 2023 v.300 pp. 115743
ISSN:
0378-8741
Subject:
epithelium,   etc   ; Influenza A virus; Oriental traditional medicine; Trollius chinensis; Western blotting; blood; cytoplasm; fluorescent antibody technique; lungs; nasal cavity; pharmacology; pharyngitis; pneumonia; spleen; therapeutics; viruses;     Show all 16 Subjects
Abstract:
... The flowers of Trollius chinensis Bunge (Ranunculaceae) is a traditional Chinese medicine used to treat various inflammatory diseases, including upper respiratory infections, chronic tonsillitis, and pharyngitis. Recently, there has been growing research on the antiviral role of the flowers of T. chinensis Bunge. However, little is known about its anti-influenza virus effects and the underlying me ...
DOI:
10.1016/j.jep.2022.115743

4. Damage signal induced by Bacillus thuringiensis infection triggers immune responses via a DAMP molecule in lepidopteran insect, Spodoptera exigua

Author:
Md Tafim Hossain Hrithik; Shabbir Ahmed; Yonggyun Kim
Source:
Developmental and comparative immunology 2023 v.139 pp. 104559
ISSN:
0145-305X
Subject:
epithelium,   etc   ; Bacillus thuringiensis; RNA interference; Spodoptera exigua; bacterial infections; cadherins; cytokines; eicosanoids; entomopathogenic bacteria; gene induction; genes; immune system; insect immunity; insects; midgut; nitric oxide; phospholipases;     Show all 17 Subjects
Abstract:
... Insect immunity defends the infection of an insect pathogenic bacterium, Bacillus thuringiensis (Bt). However, it was not clear on the recognition of Bt infection by the insect immune system. This study tested a physiological function of dorsal switch protein 1 (DSP1) in the Bt infection. DSP1 is classified into HMGB1-like damage-associated molecular pattern (DAMP) in insects. Upon Bt infection in ...
DOI:
10.1016/j.dci.2022.104559

5. Neutralization of interleukin-11 attenuates silica particles-induced pulmonary inflammation and fibrosis in vivo

Author:
Jixuan Ma; Yujia Xie; Yiju Xu; Pei Gu; Yingdie Zhang; Lieyang Fan; Yun Zhou; Haijiao Wang; Ting Zhou; Jintong He; Dongming Wang; Weihong Chen
Source:
Journal of environmental sciences (China) 2023 v.126 pp. 772-783
ISSN:
1001-0742
Subject:
epithelium,   etc   ; antibodies; collagen; environmental exposure; fibroblasts; fibrosis; gelatinase A; glycoproteins; inflammation; interleukin-11; interleukin-6; lungs; mice; mitogen-activated protein kinase; necrosis; neoplasms; neutralization; silica; therapeutics; China;     Show all 20 Subjects
Abstract:
... Environmental exposure to crystalline silica particles can lead to silicosis, which is one of the most serious pulmonary interstitial fibrosis around the world. Unfortunately, the exact mechanism on silicosis is unclear, and the effective treatments are lacking to date. In this study, we aim to explore the molecular mechanism by which interleukin-11 (IL-11) affects silica particles-induced lung in ...
DOI:
10.1016/j.jes.2022.03.015

6. Comparative pulmonary toxicity assessment of tungsten trioxide and tungsten trioxide hydrate nanoparticles

Author:
Hsin Her Yu; Yi-Chun Chen; Han-Pang Su; Liliang Chen; Hung-Hsiang Chen; Kun-Yi Andrew Lin; Chia-Hua Lin
Source:
Science of the total environment 2023 v.855 pp. 158885
ISSN:
0048-9697
Subject:
epithelium,   etc   ; apoptosis; cytotoxicity; elastase; environment; gene expression; heme oxygenase (biliverdin-producing); humans; interleukin-6; lungs; nanoparticles; neutrophils; oxidation; photocatalysis; reactive oxygen species; respiratory tract diseases; risk; secretion; superoxide dismutase; tungsten oxide;     Show all 20 Subjects
Abstract:
... Tungsten trioxide (WO₃)-based nanoparticles (NPs) are gaining popularity because of their exciting potential for photocatalytic applications; however, the toxic potential of WO₃-based NPs remains a concern. In this study, we evaluated the toxic risk of WO₃ NPs and hydrated WO₃ NPs (WO₃·H₂O NPs) using lung cells and explored the underlying mechanism. WO₃ NPs and WO₃·H₂O NPs significantly decreased ...
DOI:
10.1016/j.scitotenv.2022.158885

7. Sex and reproductive development impact skin mucosal epithelium immunity, antimicrobial capacity, and up-regulation of immune-related gene of goldfish (Carassius auratus)

Author:
Zahra Roosta; Bahram Falahatkar; Mirmasoud Sajjadi; Hamed Paknejad; Arash Akbarzadeh; Patrick Kestemont
Source:
Developmental and comparative immunology 2023 v.138 pp. 104494
ISSN:
0145-305X
Subject:
epithelium,   etc   ; Carassius auratus; Enterococcus faecium; Micrococcus luteus; Staphylococcus aureus; alkaline phosphatase; antimicrobial properties; calcium; complement; females; gene expression; genes; goldfish; innate immunity; liver; lysozyme; males; models; mucosal immunity; peroxidase; spermatogenesis; spermiation; vitellogenesis;     Show all 23 Subjects
Abstract:
... This study evaluated the epidermis mucosal capacity of goldfish (Carassius auratus) during different stages of reproductive development in both females and males. In this regard, the activity of mucolytic immune enzymes, i.e., lysozyme, complement and peroxidase, as well as the activity of alkaline phosphatase (ALP) were evaluated. There were five stages for females i.e., immature (f1), cortical a ...
DOI:
10.1016/j.dci.2022.104494

8. Effects of two fish-derived probiotics on growth performance, innate immune response, intestinal health, and disease resistance of Procambarus clarkii

Author:
Lei Zhu; Yiming Kong; Xulu Chang; Junchang Feng; Xinru Wang; Libo Hou; Xianliang Zhao; Chao Pei; Xianghui Kong
Source:
Aquaculture 2023 v.562 pp. 738765
ISSN:
0044-8486
Subject:
epithelium,   etc   ; Bacillus amyloliquefaciens; Lactococcus lactis; Procambarus clarkii; acid phosphatase; alkaline phosphatase; aquaculture; crayfish; disease resistance; enzyme activity; gene expression; glutathione peroxidase; growth performance; hemocytes; intestinal microorganisms; intestines; lysozyme; pathogens; phagocytosis; probiotics; specific growth rate; weight gain;     Show all 22 Subjects
Abstract:
... Selection of the appropriate strain for particular aquatic animals is necessary for the desirable benefits of probiotics application in aquaculture, however, it is not very clear whether fish-derived probiotics could provide beneficial effects on invertebrates. In the present study, two fish-derived probiotics, Bacillus amyloliquefaciens, and Lactococcus lactis, were administrated as feed additive ...
DOI:
10.1016/j.aquaculture.2022.738765

9. Understanding HAIs: Ally proteins in the fight against cancer

Author:
Annika W. Nonboe; Zuzanna H. Bald; Lotte K. Vogel
Source:
FEBS journal 2022 v.289 no.12 pp. 3416-3418
ISSN:
1742-464X
Subject:
epithelium,   etc   ; serine proteinases;     Show all 2 Subject
Abstract:
... Understanding how HAI‐1 and HAI‐2 regulate the epithelial serine protease matriptase may hold the key to curing epithelial‐derived cancer. HAIs are serine protease inhibitors that inhibit matriptase and have a poorly understood effect on the presence of matriptase protein in cells. In this issue of The FEBS Journal, Yamashita et al. provide much‐needed new insights into this effect, describing it ...
DOI:
10.1111/febs.16399

10. Transcriptome analysis and pattern recognition receptors (PRRs) identification in different tissues of adult Pacific oysters infected with Vibrio parahaemolyticus

Author:
Petcharat Namwong; Shuang Wang; Qing Kong; Haijin Mou; Lei Ma; Prapansak Srisapoome
Source:
Aquaculture 2023 v.562 pp. 738824
ISSN:
0044-8486
Subject:
epithelium,   etc   ; Crassostrea gigas; Gram-negative bacteria; Vibrio parahaemolyticus; adults; aquaculture industry; bacterial adhesion; bacterial infections; carbohydrate binding; cytoskeleton; data collection; fluorescent antibody technique; food sanitation; galectins; gene expression; gene expression regulation; genes; host-pathogen relationships; macrophages; mannose; oxidative stress; pathogens; peptidoglycans; peroxidase; phagocytosis; recombinant proteins; shellfish culture; transcriptomics;     Show all 28 Subjects
Abstract:
... Contamination of V. parahaemolyticus in raw product and culture areas of Crassostrea gigas has been a concern in food hygiene and infectious diseases in the shellfish aquaculture industry for decades. Although numerous researchers have presently objective of decreasing pathogen microorganism contaminated load in raw oysters or genetics improvement for prevention, the in-depth information at the mo ...
DOI:
10.1016/j.aquaculture.2022.738824

11. Survey of the exocrine glands in workers of the ant Leptanilla clypeata

Author:
J. Billen; N. Vanelderen; F. Ito
Source:
Insectes sociaux 2022 v.69 no.2-3 pp. 215-228
ISSN:
0020-1812
Subject:
epithelium,   etc   ; Protanilla; petioles; surveys;     Show all 4 Subjects
Abstract:
... Our morphological study of the exocrine system in workers of Leptanilla clypeata revealed the presence of at least 23 glands. Among these, the dorsoproximal intramandibular gland represents a novel structure for social insects. Another novel gland may exist in the ventral part of the postpetiolus; both the petiole and postpetiole contain conspicuous clusters of large gland cells. The occurrence of ...
DOI:
10.1007/s00040-022-00861-9

12. Systemically circulating bacterial extracellular vesicles: origin, fate, and function

Author:
An Hendrix; Olivier De Wever
Source:
Trends in microbiology 2022 v.30 no.3 pp. 213-216
ISSN:
0966-842X
Subject:
epithelium,   etc   ; biochemical compounds; excretion; humans;     Show all 4 Subjects
Abstract:
... Bacteria contribute to human host (patho)physiology through the production of a myriad of biomolecules enclosed in membrane vesicles [bacterial extracellular vesicles (BEVs)]. Recent research revealed that BEVs, as a functional output of bacteria, enter the systemic circulation. Here, we highlight the current state of knowledge on the origin, translocation, distribution, function, and excretion or ...
DOI:
10.1016/j.tim.2021.12.012

13. Post-hatch changes in the histological structure of the oviduct and associated 17β-estradiol profiles in guinea hens (Numida meleagris)

Author:
Ibn Iddriss Abdul-Rahman; Jane Robinson
Source:
Canadian journal of animal science 2022 v.102 no.3 pp. 501-508
ISSN:
0008-3984
Subject:
epithelium,   etc   ; estradiol; guineafowl; histology; oviducts;     Show all 5 Subjects
Abstract:
... There are limited data available on the biology of guinea fowls. The objective of this study was to document post-hatch histological and stereological changes in the oviducts of 56 guinea hens and associated 17β-estradiol profiles until 32 weeks of age and to explore changes in the oviducal mucosal fold as an index of oviducal growth. Mucosal folds in all regions of the oviduct increased significa ...
DOI:
10.1139/cjas-2022-0010

14. Recirculating Foxp3+ regulatory T cells are restimulated in the thymus under Aire control

Author:
Jonathan Charaix; Alexia Borelli; Jérémy C. Santamaria; Lionel Chasson; Matthieu Giraud; Arnauld Sergé; Magali Irla
Source:
Cellular and molecular life sciences 2022 v.79 no.7 pp. 355
ISSN:
1420-682X
Subject:
epithelium,   etc   ; autoimmunity; bone marrow; coculture;     Show all 4 Subjects
Abstract:
... Thymically-derived Foxp3⁺ regulatory T cells (Tᵣₑg) critically control immunological tolerance. These cells are generated in the medulla through high affinity interactions with medullary thymic epithelial cells (mTEC) expressing the Autoimmune regulator (Aire). Recent advances have revealed that thymic Tᵣₑg contain not only developing but also recirculating cells from the periphery. Although Aire ...
DOI:
10.1007/s00018-022-04328-9

15. Submucosal resection via a transanal approach for treatment of epithelial rectal tumors – a multicenter study

Author:
Matteo Cantatore; Juan Carlos Jimeno Sandoval; Smita Das; Alberto Sesana; Tim Charlesworth; Tony Ryan; Emanuela M. Morello; Matteo Gobbetti; Filippo Cinti; Matteo Rossanese
Source:
Veterinary surgery 2022 v.51 no.3 pp. 397-408
ISSN:
0161-3499
Subject:
epithelium,   etc   ; carcinoma; death; resection; risk;     Show all 5 Subjects
Abstract:
... OBJECTIVE: To report complications and long‐term outcomes after submucosal resections of benign and malignant epithelial rectal masses. STUDY DESIGN: Retrospective multicentric study. SAMPLE POPULATION: Medical records of 93 dogs at 7 referral hospitals. METHODS: Records were reviewed for surgical time, diagnosis, margins, complications, and recurrences. Survival of dogs was evaluated based on tum ...
DOI:
10.1111/vsu.13766

16. When is a neuron like an epithelial cell

Author:
Maxwell G. Heiman
Source:
Developmental biology 2022 v.489 pp. 161-164
ISSN:
0012-1606
Subject:
epithelium,   etc   ; epithelial cells; olfactory receptors;     Show all 3 Subjects
Abstract:
... Neurons and epithelia are viewed as fundamentally different cell types, yet some sensory neurons exhibit hallmarks of epithelial cells. For example, they use tight junctions to form a diffusion barrier continuous with the skin or other epithelia and they exhibit bona fide apical-basal polarity, with an outward-facing apical surface that is biochemically and functionally distinct from their inward- ...
DOI:
10.1016/j.ydbio.2022.06.012

17. Wound healing in animals: a review of physiology and clinical evaluation

Author:
Cassie N. Lux
Source:
Veterinary dermatology 2022 v.33 no.1 pp. 91
ISSN:
0959-4493
Subject:
epithelium,   etc   ; clinical examination; inflammation; veterinary medicine;     Show all 4 Subjects
Abstract:
... Wound healing is a complicated process consisting of overlapping phases directed and regulated by many mediators of healing produced locally at the wound. The end goal of wound healing is the production of tissue at the site of injury which has a similar structure and provides protection to the body. Any alterations in the normal healing process can lead to delayed healing or additional tissue dam ...
DOI:
10.1111/vde.13032

18. Association between Cervical Microbiota and HPV: Could This Be the Key to Complete Cervical Cancer Eradication?

Author:
Eliano Cascardi; Gerardo Cazzato; Antonella Daniele; Erica Silvestris; Gennaro Cormio; Giovanni Di Vagno; Antonio Malvasi; Vera Loizzi; Salvatore Scacco; Vincenzo Pinto; Ettore Cicinelli; Eugenio Maiorano; Giuseppe Ingravallo; Leonardo Resta; Carla Minoia; Miriam Dellino
Source:
Biology 2022 v.11 no.8 pp. -
ISSN:
2079-7737
Subject:
epithelium,   etc   ; immunity; microorganisms; uterine cervical neoplasms;     Show all 4 Subjects
Abstract:
... The heterogeneity of the cervico-vaginal microbiota can be appreciated in various conditions, both pathological and non-pathological, and can vary according to biological and environmental factors. Attempts are still in course to define the interaction and role of the various factors that constitute this community of commensals in immune protection, inflammatory processes, and the onset of precanc ...
DOI:
10.3390/biology11081114

19. Molecular Mechanisms and Key Processes in Interstitial, Hemorrhagic and Radiation Cystitis

Author:
Clément Brossard; Anne-Charlotte Lefranc; Anne-Laure Pouliet; Jean-Marc Simon; Marc Benderitter; Fabien Milliat; Alain Chapel
Source:
Biology 2022 v.11 no.7 pp. -
ISSN:
2079-7737
Subject:
epithelium,   etc   ; bladder; inflammation; interstitial cystitis; pain;     Show all 5 Subjects
Abstract:
... Cystitis is a bladder disease with a high rate of prevalence in the world population. This report focuses on Interstitial Cystitis (IC), Hemorrhagic Cystitis (HC) and Chronic Radiation Cystitis. These pathologies have different etiologies, but they share common symptoms, for instance, pain, bleeding, and a contracted bladder. Overall, treatments are quite similar for abacterial cystitis, and inclu ...
DOI:
10.3390/biology11070972

20. Morphometric Features and Microanatomy of the Lingual Filiform Papillae in the Wistar Rat

Author:
Elena Huțanu; Aurel Damian; Viorel Miclăuș; Ioana A. Rațiu; Vasile Rus; Ion Vlasiuc; Adrian F. Gal
Source:
Biology 2022 v.11 no.6 pp. -
ISSN:
2079-7737
Subject:
epithelium,   etc   ; histology; keratinization; morphometry; rats; tongue;     Show all 6 Subjects
Abstract:
... The mammalian tongue plays a fundamental role in various physiological and behavioral activities. Significant morphological variations have been recorded in the tongue of several species. This study aims to obtain detailed histological and morphometric information about the filiform papillae on the surface of rat tongue. The tongues of five 10-month-old Wistar rats were utilized, which were later ...
DOI:
10.3390/biology11060920