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1. Single-cell branching morphogenesis in the Drosophila trachea

Author:
Best, Benedikt T.
Source:
Developmental biology 2019 v.451 no.1 pp. 5-15
ISSN:
0012-1606
Subject:
epithelium,   etc   ; Drosophila melanogaster; animals; larvae; morphogenesis; oxygen;     Show all 6 Subjects
Abstract:
... The terminal cells of the tracheal epithelium in Drosophila melanogaster are one of the few known cell types that undergo subcellular morphogenesis to achieve a stable, branched shape. During the animal's larval stages, the cells repeatedly sprout new cytoplasmic processes. These grow very long, wrapping around target tissues to which the terminal cells adhere, and are hollowed by a gas-filled sub ...
DOI:
10.1016/j.ydbio.2018.12.001

2. Molecular components and polarity of radial glial cells during cerebral cortex development

Author:
Chou, Fu-Sheng; Li, Rong; Wang, Pei-Shan
Source:
Cellular and molecular life sciences 2018 v.75 no.6 pp. 1027-1041
ISSN:
1420-682X
Subject:
epithelium,   etc   ; cerebral cortex; neuroglia;     Show all 3 Subjects
Abstract:
... Originating from ectodermal epithelium, radial glial cells (RGCs) retain apico-basolateral polarity and comprise a pseudostratified epithelial layer in the developing cerebral cortex. The apical endfeet of the RGCs faces the fluid-filled ventricles, while the basal processes extend across the entire cortical span towards the pial surface. RGC functions are largely dependent on this polarized struc ...
DOI:
10.1007/s00018-017-2680-0

3. Wax gland size according to worker age in Friesella schrottkyi

Author:
Justino, Cíntia Eleonora Lopes; Noll, Fernando Barbosa; Mateus, Sidnei; Billen, Johan
Source:
Apidologie 2018 v.49 no.3 pp. 359-366
ISSN:
0044-8435
Subject:
epithelium,   etc   ; nests; polyethism; stingless bees;     Show all 4 Subjects
Abstract:
... Wax production is one of the stingless bee activities that is related with nest building. We studied wax gland size in workers of the stingless bee Friesella schrottkyi at nine different ages: 0, 4, 5, 8, 10, 13, 14, 15, and 20 days. In the large majority of workers, we observed a conspicuous epithelium in abdominal tergites III, IV, and V. Our results clearly show a link between worker age and wa ...
DOI:
10.1007/s13592-018-0561-7

4. Lack of effect of a topical regenerative agent on re-epithelialization rate of canine spontaneous chronic corneal epithelial defects: A randomized, double-masked, placebo-controlled study

Author:
Sebbag, L.; Allbaugh, R.; Strong, T.; Strauss, R.; Wehrman, R.; Foote, B.; Peterson, C.; Ben-Shlomo, G.
Source:
The veterinary journal 2018 v.233 pp. 63-65
ISSN:
1090-0233
Subject:
epithelium,   etc   ; cornea; debridement; dogs; placebos;     Show all 5 Subjects
Abstract:
... Spontaneous chronic corneal epithelial defects (SCCEDs) are characteristic ulcers in dogs that are refractory to healing. The aim of the study was to evaluate the use of a topical regenerative agent to promote healing of SCCEDs. Nineteen dogs (20 eyes) were randomized to receive either regenerative agent (10 eyes) or placebo (10 eyes) every 48h following corneal debridement, which was repeated 1 w ...
DOI:
10.1016/j.tvjl.2018.01.003

5. La consommation de prébiotiques par la mère limite la survenue d’allergie chez la descendance

Author:
Bodinier, Marie; Barbarot, Sébastien; Selle, Amandine
Source:
Cahiers de nutrition et de diététique 2019 v.54 no.4 pp. 215-222
ISSN:
0007-9960
Subject:
epithelium,   etc   ; hypersensitivity; immune system; lifestyle; microorganisms; prebiotics; public health;     Show all 7 Subjects
Abstract:
... Allergies are a real public health problem. Today, there is no effective preventive strategy. They are linked to dysfunctions of microbiota, epithelial barriers and immune system detectable in early life and in relation with our modern lifestyle. Maternal nutritional strategies, such as prebiotics, seem very encouraging to prevent these increasing pathologies. ...
DOI:
10.1016/j.cnd.2019.04.003

6. Early taste buds are from Shh+ epithelial cells of tongue primordium in distinction from mature taste bud cells which arise from surrounding tissue compartments

Author:
Kramer, Naomi; Chen, Guiqian; Ishan, Mohamed; Cui, Xiaogang; Liu, Hong-Xiang
Source:
Biochemical and biophysical research communications 2019 v.515 no.1 pp. 149-155
ISSN:
0006-291X
Subject:
epithelium,   etc   ; epithelial cells; keratin; mice; neonates; palps; taste; tongue;     Show all 8 Subjects
Abstract:
... Mammalian taste buds emerge perinatally and most become mature 3–4 weeks after birth. Mature taste bud cells in rodents are known to be renewed by the surrounding K14+ basal epithelial cells and potentially other progenitor source(s), but the dynamics between initially developed taste buds and surrounding tissue compartments are unclear. Using the K14-Cre and Dermo1-Cre mouse lines to trace epithe ...
DOI:
10.1016/j.bbrc.2019.05.132

7. Improving Techniques to Study Equine Cervical Mucociliary Clearance

Author:
Hawkes, Melissa; Richard, Anna; Oldfield, Chelsie; Toothaker, Alec; Stokes, Martin; Causey, Robert
Source:
Journal of equine veterinary science 2019 v.78 pp. 46-52
ISSN:
0737-0806
Subject:
epithelium,   etc   ; carbon; cervix; industry; mares; microparticles; polyethylene; uterus;     Show all 8 Subjects
Abstract:
... Postbreeding bacterial uterine infections inflict major losses on the equine industry. Microcurrents propelled by ciliated cells between the folds of the uterus and cervix have been proposed as a means by which contaminants are expelled. Previous data have shown possible ciliary microcurrents propelling carbon particles, occasionally rotating, through cervical folds. However, adherence to the epit ...
DOI:
10.1016/j.jevs.2019.03.009

8. Apical constriction is necessary for crypt formation in small intestinal organoids

Author:
Hartl, Leonie; Huelsz-Prince, Guizela; van Zon, Jeroen; Tans, Sander J.
Source:
Developmental biology 2019 v.450 no.2 pp. 76-81
ISSN:
0012-1606
Subject:
epithelium,   etc   ; biomechanics; bud initiation; cell biology; homeostasis; intestines; myosin;     Show all 7 Subjects
Abstract:
... Small intestinal organoids have become an important tool to study crypt homeostasis, cell fate dynamics and tissue biomechanics. Yet, the mechanisms that drive the budding of crypts from the smooth organoid epithelium remain incompletely understood. Locally enhanced proliferation has been suggested to induce tissue buckling and crypt initiation. Here we report that changes in cell morphology play ...
DOI:
10.1016/j.ydbio.2019.03.009

9. Alpha-enolase staining patterns in the renal tissues of cats with and without chronic kidney disease

Author:
McLeland, Shannon; Quimby, Jessica; Lappin, Michael R.
Source:
Veterinary immunology and immunopathology 2019 v.212 pp. 23-26
ISSN:
0165-2427
Subject:
epithelium,   etc   ; cats; histopathology; immunohistochemistry; nephritis; pathogenesis; phosphopyruvate hydratase; staining;     Show all 8 Subjects
Abstract:
... Renal α-enolase has variable expression in inflammatory and neoplastic diseases. Therefore, in order to define the distribution of α-enolase in renal tissues of cats, an immunohistochemistry assay was validated and described here. Tissues from 29 cats with IRIS Stage 2–4 CKD, 8 control cats < 2 years of age, and 4 control cats> 10 years of age were assessed. Interstitial nephritis was the predomin ...
DOI:
10.1016/j.vetimm.2019.04.009

10. SHP-1 inhibits renal ischemia reperfusion injury via dephosphorylating ASK1 and suppressing apoptosis

Author:
Tian, Hongzhe; Tan, Rumeng; Ye, Bogen; Yan, Sijia; Sui, Mingxing; Zhao, Wenyu; Zhang, Lei; Zhu, Youhua; Zeng, Li
Source:
Biochemical and biophysical research communications 2019 v.513 no.2 pp. 360-367
ISSN:
0006-291X
Subject:
epithelium,   etc   ; apoptosis; cell lines; enzymes; ischemia; protective effect; reperfusion injury;     Show all 7 Subjects
Abstract:
... Apoptosis of tubular epithelium cells (TECs) plays critical roles in renal ischemia reperfusion (I/R) injury, but the molecular regulatory mechanisms of apoptosis still require further investigation. Recently, phosphatase family members have been suggested to regulate multiple aspects of the injury and regeneration response. However, the roles of SHP-1, an important protein-tyrosine phosphatase, i ...
DOI:
10.1016/j.bbrc.2019.03.187

11. CTCF deficiency causes expansion of the sensory domain in the mouse cochlea

Author:
Ma, Ji-Hyun; Kim, Hyoung-Pyo; Shin, Jeong-Oh
Source:
Biochemical and biophysical research communications 2019 v.512 no.4 pp. 896-901
ISSN:
0006-291X
Subject:
epithelium,   etc   ; GATA transcription factors; chromatin; ears; epigenetics; mice; neurons;     Show all 7 Subjects
Abstract:
... The cochlea in the mammalian inner ear is a sensitive and sharply organized sound-detecting structure. The proper specification of neurosensory-competent domain in the otic epithelium is required for the formation of mature neuronal and sensory domains. Genetic studies have provided many insights into inner ear development, but there have been few epigenetic studies of inner ear development. CTCF ...
DOI:
10.1016/j.bbrc.2019.03.127

12. Cholesteatoma in a cat

Author:
Alexander, Akash; Mahoney, Paul; Scurrell, Emma; Baines, Stephen
Source:
Journal of feline medicine and surgery open reports 2019 v.5 no.1
ISSN:
2055-1169
Subject:
epithelium,   etc   ; biopsy; cats; ear diseases; females; histopathology; image analysis; keratin;     Show all 8 Subjects
Abstract:
... A 14-year-old neutered female Burmese cat was referred for investigation of a caudal oropharyngeal mass. CT showed a thin walled cyst-like structure filling and expanding from the right tympanic bulla. Histopathology showed fragments of mildly dysplastic squamous epithelium and aggregates of keratin. These findings were considered consistent with a diagnosis of cholesteatoma. To the best of our kn ...
DOI:
10.1177/2055116919848086

13. TRIM21 mediates ubiquitination of Snail and modulates epithelial to mesenchymal transition in breast cancer cells

Author:
Jin, Yue; Zhang, Yu; Li, Boyuan; Zhang, Jing; Dong, Zhiwen; Hu, Xin; Wan, Youzhong
Source:
International journal of biological macromolecules 2019 v.124 pp. 846-853
ISSN:
0141-8130
Subject:
epithelium,   etc   ; breast neoplasms; gene expression; neoplasm cells; ubiquitination;     Show all 5 Subjects
Abstract:
... Migration and invasion of cancer cells are greatly increased during epithelial to mesenchymal transition (EMT). Depletion of TRIM21 promotes the migration and invasion of MCF7 and T47D cells, and changes the expression of genes that regulate EMT. TRIM21 interacts with Snail, a master regulator of EMT. Overexpression of TRIM21 leads to increased ubiquitination and proteosomal degradation of Snail, ...
DOI:
10.1016/j.ijbiomac.2018.11.269

14. Structural insight into Wnt signaling inhibition by Clostridium difficile toxin B

Author:
Chen, Peng; Tao, Liang; Liu, Zheng; Dong, Min; Jin, Rongsheng
Source:
TheFEBS journal 2019 v.286 no.5 pp. 874-881
ISSN:
1742-464X
Subject:
epithelium,   etc   ; Clostridium difficile; humans; morbidity; mortality; pathogenesis; receptors; therapeutics; virulence;     Show all 9 Subjects
Abstract:
... The incidence of Clostridium difficile infection (CDI) has increased significantly worldwide, causing substantial morbidity and mortality. One of the major virulence factor, TcdB, manages to enter the colonic epithelia via the human frizzled proteins (FZDs), which are physiological receptors for Wnt morphogens. Binding of TcdB to FZDs inhibits Wnt signaling, which may contribute to pathogenesis of ...
DOI:
10.1111/febs.14681

15. Bardet–Biedl Syndrome proteins regulate cilia disassembly during tissue maturation

Author:
Patnaik, Sarita Rani; Kretschmer, Viola; Brücker, Lena; Schneider, Sandra; Volz, Ann-Kathrin; Oancea-Castillo, Liliana del Rocio; May-Simera, Helen Louise
Source:
Cellular and molecular life sciences 2019 v.76 no.4 pp. 757-775
ISSN:
1420-682X
Subject:
epithelium,   etc   ; cilia; gene expression; homeostasis; organelles; organogenesis; proteins; retina;     Show all 8 Subjects
Abstract:
... Primary cilia are conserved organelles that mediate cellular communication crucial for organogenesis and homeostasis in numerous tissues. The retinal pigment epithelium (RPE) is a ciliated monolayer in the eye that borders the retina and is vital for visual function. Maturation of the RPE is absolutely critical for visual function and the role of the primary cilium in this process has been largely ...
DOI:
10.1007/s00018-018-2966-x

16. Treatment of spontaneous chronic corneal epithelial defects (SCCEDs) with diamond burr debridement vs combination diamond burr debridement and superficial grid keratotomy

Author:
Wu, Doris; Smith, Sara M.; M. Stine, Jessica; M. Michau, Tammy; Miller, Thomas R.; Pederson, Samantha L.; Freeman, Kate S.
Source:
Veterinary ophthalmology 2018 v.21 no.6 pp. 622-631
ISSN:
1463-5216
Subject:
epithelium,   etc   ; cornea; debridement; dogs; medical records; ophthalmology;     Show all 6 Subjects
Abstract:
... OBJECTIVE: To evaluate the efficacy of diamond burr debridement (DBD) vs a combination of diamond burr debridement with superficial grid keratotomy (DBD+SGK) for the treatment of spontaneous chronic corneal epithelial defects (SCCEDs) in dogs. PROCEDURE: Medical records of dogs diagnosed with SCCEDs from three different institutions that received a DBD or DBD+SGK between 2003 and 2015 were reviewe ...
DOI:
10.1111/vop.12556

17. Roles and applications of probiotic Lactobacillus strains

Author:
Zhang, Zhongwang; Lv, Jianliang; Pan, Li; Zhang, Yongguang
Source:
Applied microbiology and biotechnology 2018 v.102 no.19 pp. 8135-8143
ISSN:
0175-7598
Subject:
epithelium,   etc   ; Lactobacillus; health promotion; immunomodulation; probiotics;     Show all 5 Subjects
Abstract:
... Lactobacilli are recognized as probiotics on account of their health-promoting effects in the host. The aim of this review is to summarize current knowledge of the mechanisms of the adaption factors and main functions of lactobacilli that exert health-promoting effects in the host and to discuss important applications in animal and human health. The adaption mechanisms of lactobacilli facilitate i ...
DOI:
10.1007/s00253-018-9217-9

18. Knockout of NCOA5 impairs proliferation and migration of hepatocellular carcinoma cells by suppressing epithelial-to-mesenchymal transition

Author:
He, Jingcai; Zhang, Wan; Li, Aimin; Chen, Fengsheng; Luo, Rongcheng
Source:
Biochemical and biophysical research communications 2018 v.500 no.2 pp. 177-183
ISSN:
0006-291X
Subject:
epithelium,   etc   ; gene editing; hepatoma; microparticles; neoplasm cells;     Show all 5 Subjects
Abstract:
... Nuclear receptor coactivator 5 (NCOA5) plays important roles in the development of a variety of malignancies. However, the underlying mechanisms remain obscure. In this study, we successfully generated the NCOA5 knockout hepatocellular carcinoma (HCC) cells by CRISPR/Cas9 - mediated genome editing and found that knockout of NCOA5 inhibited the proliferation and tumor microsphere formation of HCC c ...
DOI:
10.1016/j.bbrc.2018.04.017

19. Polarized transport across root epithelia

Author:
Ramakrishna, Priya; Barberon, Marie
Source:
Current opinion in plant biology 2019 v.52 pp. 23-29
ISSN:
1369-5266
Subject:
epithelium,   etc   ; digestive system; endodermis; growth and development; nutrients; roots; soil; suberin;     Show all 8 Subjects
Abstract:
... Plant roots explore the soil to acquire water and nutrients which are often available at concentrations that drastically differ from the plant’s actual need for growth and development. This stark difference between availability and requirement can be dealt with owing to the root’s architecture as an inverted gut. In roots, the two epithelial characteristics (selective acquisition and diffusion bar ...
DOI:
10.1016/j.pbi.2019.05.010

20. Primary cilia in murine palatal rugae development

Author:
Nakaniwa, Mayuko; Kawasaki, Maiko; Kawasaki, Katsushige; Yamada, Akane; Meguro, Fumiya; Takeyasu, Maeda; Ohazama, Atsushi
Source:
Gene expression patterns 2019 v.34 pp. 119062
ISSN:
1567-133X
Subject:
epithelium,   etc   ; cilia; embryogenesis; in situ hybridization; mice; models; organogenesis; palate; signal transduction;     Show all 9 Subjects
Abstract:
... Periodic patterning of iterative structures is a fundamental process during embryonic development, since these structures are diverse across the animal kingdom. Therefore, elucidating the molecular mechanisms in the formation of these structures promotes understanding of the process of organogenesis. Periodically patterned ridges, palatal rugae (situated on the hard palate of mammals), are an exce ...
DOI:
10.1016/j.gep.2019.119062