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1. Controlled assembly of filamentous viruses into hierarchical nano- to microstructures at liquid/liquid interfaces

Author:
Tanaka, Michihiro; Sawada, Toshiki; Li, Xiang; Serizawa, Takeshi
Source:
RSC advances 2020 v.10 no.44 pp. 26313-26318
ISSN:
2046-2069
Subject:
etiological agents,   etc   ; emulsifying; liquids; microstructure; nanomaterials; viruses;     Show all 6 Subjects
Abstract:
... Recently, viruses have been regarded as useful molecular assemblies for materials applications rather than as disease-causing agents. The orderly assembled structures of the viruses are highly related to the resultant properties and functions of the assemblies; however, methods to control the assembly are still limited. Here, we demonstrated the assembly of filamentous viruses into hierarchical na ...
DOI:
10.1039/d0ra04529b

2. Interplay between Histomonas meleagridis and Bacteria: Mutualistic or Predator–Prey?

Author:
Bilic, Ivana; Hess, Michael
Source:
Trends in parasitology 2020 v.36 no.3 pp. 232-235
ISSN:
1471-4922
Subject:
etiological agents,   etc   ; Histomonas meleagridis; bacteria; parasites; poultry diseases;     Show all 5 Subjects
Abstract:
... Histomonas meleagridis is an extracellular protozoan parasite and the aetiological agent of histomonosis, an important poultry disease whose impact is greatly accentuated by inaccessibility of any treatment. A special feature of the parasite is its intricate interplay with bacteria in vitro and in vivo, the focus of this article. ...
DOI:
10.1016/j.pt.2019.12.015

3. Polymicrobial interactions involving fungi and their importance for the environment and in human disease

Author:
Azzam, Seham Z.; Cayme, Ginelle J.; Martinez, Luis R.
Source:
Microbial pathogenesis 2020 v.140 pp. 103942
ISSN:
0882-4010
Subject:
etiological agents,   etc   ; antibiotic resistance; drought; fungi; hosts; human diseases; humans;     Show all 7 Subjects
Abstract:
... Understanding polymicrobial interactions involving fungi in the environment and the human mycobiome is necessary to address environmental and medically related problems such as drought or antimicrobial resistance. The diversity of these interactions highlights the complexity of fungi, considering how some interactions can be antagonistic, while others synergistic. Over the years, an increase in st ...
DOI:
10.1016/j.micpath.2019.103942
PubMed:
31881258
PubMed Central:
PMC7105396

4. Microbiota, a Third Player in the Host–Plasmodium Affair

Author:
Mukherjee, Debanjan; Chora, Ângelo Ferreira; Mota, Maria M.
Source:
Trends in parasitology 2020 v.36 no.1 pp. 11-18
ISSN:
1471-4922
Subject:
etiological agents,   etc   ; Plasmodium; digestive system; homeostasis; intestinal microorganisms; malaria;     Show all 6 Subjects
Abstract:
... Plasmodium, the causative agent of malaria, is responsible for more than 200 million new infections and 400 000 deaths yearly. While in recent years the influence of the microbiota in homeostasis and a wide variety of disorders has taken center stage, its contribution during malaria infections has only now started to emerge. The few published studies suggest two distinct but complementary directio ...
DOI:
10.1016/j.pt.2019.11.001

5. Chromatin topology reorganization and transcription repression by PML-RARα in acute promyeloid leukemia

Author:
Wang, Ping; Tang, Zhonghui; Lee, Byoungkoo; Zhu, Jacqueline Jufen; Cai, Liuyang; Szalaj, Przemyslaw; Tian, Simon Zhongyuan; Zheng, Meizhen; Plewczynski, Dariusz; Ruan, Xiaoan; Liu, Edison T.; Wei, Chia-Lin; Ruan, Yijun
Source:
Genome biology 2020 v.21 no.1 pp. 110
ISSN:
1474-760X
Subject:
etiological agents,   etc   ; chromatin; genes; leukemia; neoplasm cells; topology; transcription (genetics); transcription factors;     Show all 8 Subjects
Abstract:
... BACKGROUND: Acute promyeloid leukemia (APL) is characterized by the oncogenic fusion protein PML-RARα, a major etiological agent in APL. However, the molecular mechanisms underlying the role of PML-RARα in leukemogenesis remain largely unknown. RESULTS: Using an inducible system, we comprehensively analyze the 3D genome organization in myeloid cells and its reorganization after PML-RARα induction ...
DOI:
10.1186/s13059-020-02030-2

6. Fecal transplants as a microbiome-based therapeutic

Author:
Kaakoush, Nadeem O
Source:
Current opinion in microbiology 2020 v.56 pp. 16-23
ISSN:
1369-5274
Subject:
etiological agents,   etc   ; bile acids; diet; feces; fungi; genetics; microbiome; patients; short chain fatty acids; therapeutics;     Show all 10 Subjects
Abstract:
... Impaired microbiome diversity and composition can develop into a potent etiological agent of disease and increase susceptibility to infection. Given this, interventions targeting the microbiome have developed rapidly, with healthy donor feces being a de facto source of beneficial communities employed to rebalance patients’ microbiomes. Recent evidence has demonstrated that bacterial and viral rich ...
DOI:
10.1016/j.mib.2020.05.008

7. Development of a microsphere‐based immunoassay for the serological detection of glanders in equids

Author:
Laroucau, K.; Saqib, M.; Martin, B.; Deshayes, T.; Bertin, C.; Wernery, U.; Joseph, S.; Singha, H.; Tripathi, B.N.; Beck, C.
Source:
Acta tropica 2020 v.207 pp. 105463
ISSN:
0001-706X
Subject:
etiological agents,   etc   ; Burkholderia mallei; Equidae; antigens; complement fixation tests; glanders; horses; recombinant proteins; serodiagnosis; India; Pakistan;     Show all 11 Subjects
Abstract:
... Burkholderia mallei is the etiologic agent of glanders, an infectious disease of solipeds, with renewed scientific interest due to its increasing incidence in different parts of the world. More rapid, sensitive and specific assays are required by laboratories for confirmatory testing of this disease. A microsphere‐based immunoassay consisting of beads coated with B. mallei recombinant proteins (Bi ...
DOI:
10.1016/j.actatropica.2020.105463

8. Aspergillosis in free-ranging aquatic birds

Author:
Melo, Aryse Martins; Silva-Filho, Rodolfo Pinho da; Poester, Vanice Rodrigues; von Groll, Andrea; Fernandes, Cristina Gevehr; Stevens, David A.; Sabino, Raquel; Xavier, Melissa Orzechowski
Source:
Medical mycology case reports 2020 v.28 pp. 36-38
ISSN:
2211-7539
Subject:
etiological agents,   etc   ; Aspergillus; Neotropics; aspergillosis; bird diseases; case studies; fungi; genes; necropsy; water birds;     Show all 10 Subjects
Abstract:
... Due to the difficulty in the access to free-ranging birds, data regarding Aspergillus infections in wild avian species is rare compared to captive wild and domestic birds. Objective: report three cases of Aspergillus section Fumigati causing fungal disease in free-ranging aquatic birds, with the identification of the causal agent to the species level. Case reports: The diagnosis of aspergillosis w ...
DOI:
10.1016/j.mmcr.2020.04.005
PubMed:
32405453
PubMed Central:
PMC7212181

9. A modified method for purification of Eimeria tenella sporozoites

Author:
Rentería-Solís, Zaida; Zhang, Runhui; Taha, Shahinaz; Daugschies, Arwid
Source:
Parasitology research 2020 v.119 no.4 pp. 1429-1432
ISSN:
0932-0113
Subject:
etiological agents,   etc   ; Eimeria tenella; anion exchange chromatography; birds; coccidiosis; filtration; gastrointestinal diseases; models; sporozoites;     Show all 9 Subjects
Abstract:
... Coccidiosis is an economically important gastrointestinal disease in domestic fowl. Eimeria species are the causative agents of avian coccidiosis. Current challenges in management and prevention of eimeriosis enhance the need for research in this field. Sporozoite purification is a necessary step for Eimeria spp. in vitro infection models. Current alternatives such as DE-52 anion exchange chromato ...
DOI:
10.1007/s00436-020-06602-w
PubMed:
31942639
PubMed Central:
PMC7176601

10. Evaluation of a commercial multiplex PCR for diagnosis of central nervous system (CNS) nosocomial infections

Author:
López-Amor, Lucía; García-Prieto, Emilio; Fernández-Suárez, Jonathan; Escudero, Dolores; Vázquez, Fernando; Fernández, Javier
Source:
Journal of microbiological methods 2020 v.171 pp. 105865
ISSN:
0167-7012
Subject:
etiological agents,   etc   ; blood; central nervous system; cross infection; melting; microbiology; polymerase chain reaction; sepsis (infection);     Show all 8 Subjects
Abstract:
... Nosocomial Central Nervous System (CNS) infections are often serious complications of neurosurgical procedures. Their diagnosis is complex and frequently based on microbiological culture. The aim of this work was to evaluate the effectiveness of the FilmArray® Blood Culture Identification (BCID) panel, a multiplex PCR designed to identify the most common etiologic agents of sepsis involved with no ...
DOI:
10.1016/j.mimet.2020.105865

11. Iron and Heme Metabolism at the Leishmania–Host Interface

Author:
Laranjeira-Silva, Maria Fernanda; Hamza, Iqbal; Pérez-Victoria, José M.
Source:
Trends in parasitology 2020 v.36 no.3 pp. 279-289
ISSN:
1471-4922
Subject:
etiological agents,   etc   ; Leishmania; Phlebotominae; death; ferritin; heme; human diseases; iron; leishmaniasis; macrophages; mammals; metabolism; parasites;     Show all 13 Subjects
Abstract:
... Species of the protozoan Leishmania are causative agents of human leishmaniasis, a disease that results in significant death, disability, and disfigurement around the world. The parasite is transmitted to a mammalian host by a sand fly vector where it develops as an intracellular parasite within macrophages. This process requires the acquisition of nutritional iron and heme from the host as Leishm ...
DOI:
10.1016/j.pt.2019.12.010
PubMed:
32005611
PubMed Central:
PMC7161743

12. Contrasts, contradictions and control of cholera

Author:
Lonappan, Sophia; Golecha, Ria; Balakrish Nair, G.
Source:
Vaccine 2020 v.38 pp. A4
ISSN:
0264-410X
Subject:
etiological agents,   etc   ; Vibrio cholerae; cholera; death; pandemic; planning; public health; stakeholders; vaccines;     Show all 9 Subjects
Abstract:
... Cholera has been extremely pervasive during the past four decades and continues to remain a significant public health concern. The disease has plagued humankind in the form of seven pandemics since the last two centuries. There is considerable scientific evidence based on research on cholera and its etiologic agent Vibrio cholerae, however we are still unable to accurately forecast and pre-empt th ...
DOI:
10.1016/j.vaccine.2019.08.022

13. Quercetin pentaacetate inhibits in vitro human respiratory syncytial virus adhesion

Author:
Lopes, Bruno Rafael Pereira; da Costa, Mirian Feliciano; Genova Ribeiro, Amanda; da Silva, Tiago Francisco; Lima, Caroline Sprengel; Caruso, Icaro Putinhon; de Araujo, Gabriela Campos; Kubo, Leticia Hiromi; Iacovelli, Federico; Falconi, Mattia; Desideri, Alessandro; de Oliveira, Juliana; Regasini, Luis Octavio; de Souza, Fatima Pereira; Toledo, Karina Alves
Source:
Virus research 2020 v.276 pp. 197805
ISSN:
0168-1702
Subject:
etiological agents,   etc   ; Human orthopneumovirus; acetylation; adhesion; children; cytotoxicity; elderly; energy; quercetin; respiratory system; solubility; vaccines; virion;     Show all 13 Subjects
Abstract:
... Human respiratory syncytial virus (hRSV) is one of the main etiological agents of diseases of the lower respiratory tract and is often responsible for the hospitalization of children and the elderly. To date, treatments are only palliative and there is no vaccine available. Natural products show exceptional structural diversity and they have played a vital role in drug research. Several investigat ...
DOI:
10.1016/j.virusres.2019.197805

14. What do studies in wild mammals tell us about human emerging viral diseases in Mexico?

Author:
Colunga‐Salas, Pablo; Sánchez‐Montes, Sokani; Grostieta, Estefania; Verde‐Arregoitia, Luis D.; Cabrera‐Garrido, Martín Y.; Becker, Ingeborg; León‐Paniagua, Livia
Source:
Transboundary and emerging diseases 2020 v.67 no.1 pp. 33-45
ISSN:
1865-1674
Subject:
etiological agents,   etc   ; databases; emerging diseases; humans; patients; public health; viruses; wild animals; zoonoses; Mexico;     Show all 10 Subjects
Abstract:
... Multiple species of viruses circulate in wild mammals, some of them potentially causing zoonosis. Most of the suspected viral zoonotic diseases affecting human patients remain unidentified with regard to their aetiological agent. The aim of this study is to summarize the state of knowledge of the viral richness associated with wild mammals in Mexico throughout 1900–2018 and their relationship with ...
DOI:
10.1111/tbed.13336
PubMed:
31461573
PubMed Central:
PMC7168564

15. An immunocompetent patient with culture-negative multiple brain abscesses caused by Fusobacterium nucleatum

Author:
Kenig, Ariel; Kessler, Asa; Alaa, Shaheen; Hazu, Wadia; Michael-Gaygo, Ayelet; Amit, Sharon; Orenbuch-Harroch, Efrat
Source:
Anaerobe 2020 v.65 pp. 102261
ISSN:
1075-9964
Subject:
etiological agents,   etc   ; Fusobacterium nucleatum; abscess; anaerobes; bacteria; brain; ceftriaxone; females; headache; lungs; metronidazole; morbidity; mortality; pathogen characterization; patients; ribosomal RNA;     Show all 16 Subjects
Abstract:
... The diagnosis and treatment of brain abscesses have advanced due to the utilization of modern microbiological and neurosurgical methods. Here we present a 49-year-old female patient presented with headache and neurological symptoms. Initial evaluation revealed multiple ring-enhanced brain lesions and a lung cavitary lesion initially suspected to represent a malignant process. Stereotactic aspirati ...
DOI:
10.1016/j.anaerobe.2020.102261

16. The Increasing Issue of Vancomycin-Resistant Enterococci and the Bacteriocin Solution

Author:
Reinseth, Ingvild S.; Ovchinnikov, Kirill V.; Tønnesen, Hanne H.; Carlsen, Harald; Diep, Dzung B.
Source:
Probiotics and antimicrobial proteins 2020 v.12 no.3 pp. 1203-1217
ISSN:
1867-1306
Subject:
etiological agents,   etc   ; Enterococcus faecium; World Health Organization; antibiotic resistance; antibiotics; bacteria; bacteriocins; gastrointestinal system; human diseases; humans; mortality; virulence;     Show all 12 Subjects
Abstract:
... Enterococci are commensals of human and other animals’ gastrointestinal tracts. Only making up a small part of the microbiota, they have not played a significant role in research, until the 1980s. Although the exact year is variable according to different geographical areas, this was the decade when vancomycin-resistant enterococci (VRE) were discovered and since then their role as causative agent ...
DOI:
10.1007/s12602-019-09618-6

17. Morphomolecular alterations in the skin mucosa of Atlantic salmon (Salmo salar) after exposure to peracetic acid-based disinfectant

Author:
Lazado, Carlo C.; Haddeland, Sindre; Timmerhaus, Gerrit; Berg, Ragnhild Stenberg; Merkin, Grigory; Pittman, Karin; Pedersen, Lars-Flemming
Source:
Aquaculture reports 2020 v.17 pp. 100368
ISSN:
2352-5134
Subject:
etiological agents,   etc   ; Salmo salar; disinfectants; ectoparasites; exposure duration; fish diseases; genes; histology; morphometry; mucosa; peracetic acid; salmon; therapeutics; transcription (genetics);     Show all 14 Subjects
Abstract:
... Peroxygen-based chemotherapeutants are commonly used in treating ectoparasitic infections in fish. A majority of relevant studies address the effects of these substances on the targeted causative agents, but little is known about their physiological impacts on the host organism. This study documented the changes in the skin of Atlantic salmon (Salmo salar) exposed to peracetic acid (PAA), a peroxy ...
DOI:
10.1016/j.aqrep.2020.100368

18. Campylobacter contamination of broilers: the role of transport and slaughterhouse

Author:
Rasschaert, Geertrui; De Zutter, Lieven; Herman, Lieve; Heyndrickx, Marc
Source:
International journal of food microbiology 2020 v.322 pp. 108564
ISSN:
0168-1605
Subject:
etiological agents,   etc   ; Campylobacter; European Union; campylobacteriosis; chicken carcasses; chickens; farms; flocks; human diseases; hygiene; intestines; poultry production; slaughter; slaughterhouses;     Show all 14 Subjects
Abstract:
... Campylobacter is one of the most important causative agents of foodborne illnesses worldwide. The poultry reservoir is the main source of Campylobacter. Within the broiler production chain, campylobacters can only multiply in the chicken’s intestinal tract. Intervention at farm level to reduce Campylobacter is thus preferred, but despite extensive study, no highly effective solutions have been fou ...
DOI:
10.1016/j.ijfoodmicro.2020.108564

19. Comparative transcriptomics reveals colony formation mechanism of a harmful algal bloom species Phaeocystis globosa

Author:
Zhang, Shu-Feng; Zhang, Kun; Cheng, Hua-Min; Lin, Lin; Wang, Da-Zhi
Source:
The Science of the total environment 2020 v.719 pp. 137454
ISSN:
0048-9697
Subject:
etiological agents,   etc   ; Phaeocystis globosa; algal blooms; energy; genes; glutamine; glycosaminoglycans; morphs; nitrogen metabolism; oceans; temperature; transcriptome; transcriptomics;     Show all 13 Subjects
Abstract:
... Phaeocystis globosa is a major causative agent of harmful algal blooms in the global ocean, featuring a complex polymorphic life cycle alternating between free-living solitary cells and colonial cells. Colony is the dominant morphotype during P. globosa bloom. However, the underlying mechanism of colony formation is poorly understood. Here, we comprehensively compared global transcriptomes of P. g ...
DOI:
10.1016/j.scitotenv.2020.137454

20. Detection of Leptospira interrogans in Hedgehogs from Central China

Author:
Ma, Xiao-Juan; Gong, Xiao-Qing; Xiao, Xiao; Liu, Jian-Wei; Han, Hui-Ju; Qin, Xiang-Rong; Lei, Si-Cong; Gu, Xiao-Lan; Yu, Hao; Yu, Xue-Jie
Source:
Vector borne and zoonotic diseases 2020 v.20 no.6 pp. 427-431
ISSN:
1557-7759
Subject:
etiological agents,   etc   ; DNA; Erinaceidae; Leptospira interrogans; genes; hosts; kidneys; leptospirosis; phylogeny; polymerase chain reaction; tissues; zoonoses; China;     Show all 13 Subjects
Abstract:
... Background: Leptospira is the causative agent of leptospirosis, a zoonotic disease of global importance. To have a better understanding on the host species of Leptospira, we investigated the prevalence of Leptospira species in hedgehogs in Central China. Materials and Methods: Hedgehogs were captured in Hubei Province, China in May and October, 2018. Total DNA was extracted from the kidney tissues ...
DOI:
10.1089/vbz.2019.2544