PubAg

Main content area

You searched for: Subject "genetic variation" Remove constraint Subject: "genetic variation"
Start Over

Search

50,258  Search Results

« Previous | 1 - 20 of 50,258 |
Number of results to display per page

Search Results

1. Correction to: Genetic variation and development of a SCAR marker of anemone-type flower in chrysanthemum

Author:
Yang, Xiaodong; Wu, Yangyang; Su, Jiangshuo; Ao, Ni; Guan, Zhiyong; Jiang, Jiafu; Chen, Sumei; Fang, Weimin; Chen, Fadi; Zhang, Fei
Source:
Molecular breeding 2019 v.39 no.5 pp. 68
ISSN:
1380-3743
Subject:
genetic variation,   etc   ; Chrysanthemum; flowers;     Show all 3 Subjects
Abstract:
... The original article unfortunately contains an incorrect article type. ...
DOI:
10.1007/s11032-019-0977-4

2. Genetic variability of the first-generation of Ribes sardoum, a threatened relic plant requiring translocation measures

Author:
Gentili, R.; Fenu, G.; Porceddu, M.; Bruni, I.; Citterio, S.; Bacchetta, G.
Source:
Plant biosystems 2019 v.153 no.1 pp. 1-4
ISSN:
1724-5575
Subject:
genetic variation,   etc   ; Ribes; threatened species;     Show all 3 Subjects
Abstract:
... The genetic variability of the ex situ cultivated plants of Ribes sardoum, obtained from seeds collected from the unique natural population, was investigated. Our results revealed that plants cultivated ex situ captured a higher amount of genetic diversity and this will be useful in future translocation of this threatened species. ...
DOI:
10.1080/11263504.2018.1435574

3. Signaling pathways in context

Author:
Uschner, Friedemann; Klipp, Edda
Source:
Current opinion in biotechnology 2019 v.58 pp. 155-160
ISSN:
0958-1669
Subject:
genetic variation,   etc   ; concrete; models; signal transduction;     Show all 4 Subjects
Abstract:
... The last decade has seen a rise in the development of methods and models to analyze cellular networks on all levels. The applications of this knowledge are, however, often confined to specifics of the network in concrete conditions and leveraging it is hampered by the lack of information about this context and its implications on the system. While not all cellular networks have been deciphered yet ...
DOI:
10.1016/j.copbio.2019.03.011

4. Correction to: Genetic diversity and genetic variation in morpho-physiological traits to improve heat tolerance in Spring barley

Author:
Sallam, Ahmed; Amro, Ahmed; Elakhdar, Ammar; Dawood, Mona F. A.; Kumamaru, Toshihiro; Stephen Baenziger, P.
Source:
Molecular biology reports 2019 v.46 no.2 pp. 2597
ISSN:
0301-4851
Subject:
genetic variation,   etc   ; heat tolerance; spring barley; Japan;     Show all 4 Subjects
Abstract:
... The correct spelling of the third author’s surname is Elakhdar and his current address is Agri-Bio Research Laboratory, Kyushu University, Motooka 744, Japan. The correct address for the fourth author is Agri-Bio Research Laboratory, Kyushu University, Motooka 744, Japan. ...
DOI:
10.1007/s11033-018-4503-2

5. Poor understanding of evolutionary theory is a barrier to effective conservation management

Author:
Cook, Carly N.; Sgrò, Carla M.
Source:
Conservation letters 2019 v.12 no.2 pp. e12619
ISSN:
1755-263X
Subject:
genetic variation,   etc   ; evolution; information exchange; population genetics;     Show all 4 Subjects
Abstract:
... Despite increasing recognition that integrating evolutionary theory into conservation decisions can achieve better long‐term outcomes, there has been little progress adapting management strategies. A commonly hypothesized barrier to better integration is poor understanding of evolutionary biology among conservation practitioners. To assess this claim, we surveyed conservation practitioners to dete ...
DOI:
10.1111/conl.12619

6. A Multiplexed Assay for Exon Recognition Reveals that an Unappreciated Fraction of Rare Genetic Variants Cause Large-Effect Splicing Disruptions

Author:
Cheung, Rocky; Insigne, Kimberly D.; Yao, David; Burghard, Christina P.; Wang, Jeffrey; Hsiao, Yun-Hua E.; Jones, Eric M.; Goodman, Daniel B.; Xiao, Xinshu; Kosuri, Sriram
Source:
Molecular cell 2019 v.73 no.1 pp. 183-194.e8
ISSN:
1097-2765
Subject:
genetic variation,   etc   ; exons; humans; introns; mutation;     Show all 5 Subjects
Abstract:
... Mutations that lead to splicing defects can have severe consequences on gene function and cause disease. Here, we explore how human genetic variation affects exon recognition by developing a multiplexed functional assay of splicing using Sort-seq (MFASS). We assayed 27,733 variants in the Exome Aggregation Consortium (ExAC) within or adjacent to 2,198 human exons in the MFASS minigene reporter and ...
DOI:
10.1016/j.molcel.2018.10.037

7. Exploring the Diversity of Plant Metabolism

Author:
Fang, Chuanying; Fernie, Alisdair R.; Luo, Jie
Source:
Trends in plant science 2019 v.24 no.1 pp. 83-98
ISSN:
1360-1385
Subject:
genetic variation,   etc   ; domestication; evolution; metabolism; metabolites; phenotype;     Show all 6 Subjects
Abstract:
... Plants produce a huge array of metabolites, far more than those produced by most other organisms. Unraveling this diversity and its underlying genetic variation has attracted increasing research attention. Post-genomic profiling platforms have enabled the marriage and mining of the enormous amount of phenotypic and genetic diversity. We review here achievements to date and challenges remaining tha ...
DOI:
10.1016/j.tplants.2018.09.006

8. An amplicon-based sequencing framework for accurately measuring intrahost virus diversity using PrimalSeq and iVar

Author:
Grubaugh, Nathan D.; Gangavarapu, Karthik; Quick, Joshua; Matteson, Nathaniel L.; De Jesus, Jaqueline Goes; Main, Bradley J.; Tan, Amanda L.; Paul, Lauren M.; Brackney, Doug E.; Grewal, Saran; Gurfield, Nikos; Van Rompay, Koen K. A.; Isern, Sharon; Michael, Scott F.; Coffey, Lark L.; Loman, Nicholas J.; Andersen, Kristian G.
Source:
Genome biology 2019 v.20 no.1 pp. 8
ISSN:
1474-760X
Subject:
genetic variation,   etc   ; West Nile virus; hosts; nanopores; viruses;     Show all 5 Subjects
Abstract:
... How viruses evolve within hosts can dictate infection outcomes; however, reconstructing this process is challenging. We evaluate our multiplexed amplicon approach, PrimalSeq, to demonstrate how virus concentration, sequencing coverage, primer mismatches, and replicates influence the accuracy of measuring intrahost virus diversity. We develop an experimental protocol and computational tool, iVar, f ...
DOI:
10.1186/s13059-018-1618-7

9. Molecular epidemiology of G12 rotavirus strains during eight consecutive epidemic seasons in the Basque Country (North of Spain), 2010–2018

Author:
Arana, Ainara; Jere, Khuzwayo C.; Chaguza, Chrispin; Montes, Milagrosa; Alkorta, Miriam; Iturriza-Gomara, Miren; Cilla, Gustavo
Source:
Infection, genetics, and evolution 2019 v.71 pp. 67-75
ISSN:
1567-1348
Subject:
genetic variation,   etc   ; Rotavirus; genome; genotype; molecular epidemiology; phylogeny; Spain;     Show all 7 Subjects
Abstract:
... G12 rotaviruses were first detected in Spain (Gipuzkoa province) in December 2004. After four years with no detections, G12 strains re-emerged in the 2010–2011 epidemic season, when the first European epidemic circulation of this genotype was observed in Gipuzkoa. G12 rotaviruses were also the dominant strains in 2011–2012, 2014–2015 and 2015–2016 epidemic seasons and were sporadically detected in ...
DOI:
10.1016/j.meegid.2019.03.016

10. Controlling and exploiting cell-to-cell variation in metabolic engineering

Author:
Wang, Tiebin; Dunlop, Mary J
Source:
Current opinion in biotechnology 2019 v.57 pp. 10-16
ISSN:
0958-1669
Subject:
genetic variation,   etc   ; biosynthesis; gene expression; metabolic engineering; phenotype;     Show all 5 Subjects
Abstract:
... Individual cells within a population can display diverse phenotypes due to differences in their local environment, genetic variation, and stochastic expression of genes. Understanding this cell-to-cell variation is important for metabolic engineering applications because variability can impact production. For instance, recent studies have shown that production can be highly heterogeneous among eng ...
DOI:
10.1016/j.copbio.2018.08.013

11. Nontuberculous mycobacteria in drinking water systems – the challenges of characterization and risk mitigation

Author:
Dowdell, Katherine; Haig, Sarah-Jane; Caverly, Lindsay J; Shen, Yun; LiPuma, John J; Raskin, Lutgarde
Source:
Current opinion in biotechnology 2019 v.57 pp. 127-136
ISSN:
0958-1669
Subject:
genetic variation,   etc   ; drinking water; nucleic acids; risk reduction;     Show all 4 Subjects
Abstract:
... Nontuberculous mycobacteria (NTM) pulmonary infections are a growing concern worldwide, with a disproportionate incidence in persons with pre-existing health conditions. NTM have frequently been found in municipally-treated drinking water and building plumbing, leading to the hypothesis that an important source of NTM exposure is drinking water. The identification and quantification of NTM in envi ...
DOI:
10.1016/j.copbio.2019.03.010

12. The Role of Mutation Bias in Adaptive Evolution

Author:
Svensson, Erik I.; Berger, David
Source:
Trends in ecology & evolution 2019 v.34 no.5 pp. 422-434
ISSN:
0169-5347
Subject:
genetic variation,   etc   ; evolutionary adaptation; mutation; natural selection; phenotype; population size;     Show all 6 Subjects
Abstract:
... Mutational input is the ultimate source of genetic variation, but mutations are not thought to affect the direction of adaptive evolution. Recently, critics of standard evolutionary theory have questioned the random and non-directional nature of mutations, claiming that the mutational process can be adaptive in its own right. We discuss here mutation bias in adaptive evolution. We find little supp ...
DOI:
10.1016/j.tree.2019.01.015

13. A comprehensive analysis of chimpanzee (Pan troglodytes)-specific LINE-1 retrotransposons

Author:
Lee, Sunyoung; Tang, Wanxiangfu; Liang, Ping; Han, Kyudong
Source:
Gene 2019 v.693 pp. 46-51
ISSN:
0378-1119
Subject:
genetic variation,   etc   ; Pan troglodytes; evolution; genome; humans; retrotransposons; sequence analysis;     Show all 7 Subjects
Abstract:
... Long interspersed element-1 (LINE-1 or L1) is one of the most abundant retrotransposons in the primate genomes and has contributed to their genome diversity and variations during the primate evolution. Among primate L1 subfamilies, L1Pt subfamilies include Pan troglodytes-specific L1s. L1Pt elements have been successfully expanded in the chimpanzee genome since the divergence of human and chimpanz ...
DOI:
10.1016/j.gene.2019.01.022

14. Codon and Codon-Pair Usage Tables (CoCoPUTs): Facilitating Genetic Variation Analyses and Recombinant Gene Design

Author:
Alexaki, Aikaterini; Kames, Jacob; Holcomb, David D.; Athey, John; Santana-Quintero, Luis V.; Lam, Phuc Vihn Nguyen; Hamasaki-Katagiri, Nobuko; Osipova, Ekaterina; Simonyan, Vahan; Bar, Haim; Komar, Anton A.; Kimchi-Sarfaty, Chava
Source:
Journal of molecular biology 2019
ISSN:
0022-2836
Subject:
genetic variation,   etc   ; codons; databases; genomics; human diseases; pharmaceutical industry; statistics;     Show all 7 Subjects
Abstract:
... Usage of sequential codon-pairs is non-random and unique to each species. Codon-pair bias is related to but clearly distinct from individual codon usage bias. Codon-pair bias is thought to affect translational fidelity and efficiency and is presumed to be under the selective pressure. It was suggested that changes in codon-pair utilization may affect human disease more significantly than changes i ...
DOI:
10.1016/j.jmb.2019.04.021

15. Geographical structure of bat SARS-related coronaviruses

Author:
Yu, Ping; Hu, Ben; Shi, Zheng-Li; Cui, Jie
Source:
Infection, genetics, and evolution 2019 v.69 pp. 224-229
ISSN:
1567-1348
Subject:
genetic variation,   etc   ; Chiroptera; Severe acute respiratory syndrome coronavirus; evolution; humans;     Show all 5 Subjects
Abstract:
... Bats are the natural reservoirs of severe acute respiratory syndrome coronavirus (SARS-CoV) which caused the outbreak of human SARS in 2002–2003. We introduce the genetic diversity of SARS-related coronaviruses (SARSr-CoVs) discovered in bats and provide insights on the bat origin of human SARS. We also analyze the viral geographical structure that may improve our understanding of the evolution of ...
DOI:
10.1016/j.meegid.2019.02.001

16. A new species of Ahaetulla Link, 1807 (Serpentes: Colubridae: Ahaetullinae) from India

Author:
Deepak, V.; Narayanan, Surya; Sarkar, Vivek; Dutta, Sushil K.; Mohapatra, Pratyush P.
Source:
Journal of natural history 2019 v.53 no.9-10 pp. 497-516
ISSN:
1464-5262
Subject:
genetic variation,   etc   ; Colubridae; new species; snakes; vines; India;     Show all 6 Subjects
Abstract:
... A new species of vine snake of the genus Ahaetulla is described from peninsular India. The new taxon is a medium-sized arboreal snake, readily distinguished from all other congeners by morphological and genetic differences. The new species appears to be widely distributed in Eastern Ghats and Central India with the western-most distribution extending into eastern Rajasthan. However, it is relative ...
DOI:
10.1080/00222933.2019.1589591

17. Assessment of various genetic components through NCD-I and NCD-III designs of biparental mating in opium poppy

Author:
Maurya, Krishna Nand; Pal, Pawan Kumar; Asthana, Geeta; Srivastava, Alka; Shukla, Sudhir
Source:
Journal of genetics 2019 v.98 no.1 pp. 27
ISSN:
0022-1333
Subject:
genetic variation,   etc   ; Papaver somniferum; genes; genotype; inbreeding; inheritance (genetics); variance;     Show all 7 Subjects
Abstract:
... Creation of genetic variability and development of varieties having higher yield potential depends on information about nature of gene action. The present investigation was undertaken to decipher the nature of gene action and allied genetic parameters involved in the inheritance of yield and yield-related component traits in opium poppy (Papaver somniferum L.). The biparental inbreeding progenies ...
DOI:
10.1007/s12041-019-1074-5

18. Comparisons of population density and genetic diversity in artificial and wild populations of an arborescent coral, Acropora yongei: implications for the efficacy of “artificial spawning hotspots”

Author:
Zayasu, Yuna; Suzuki, Go
Source:
Restoration ecology 2019 v.27 no.2 pp. 440-446
ISSN:
1061-2971
Subject:
genetic variation,   etc   ; Acropora; adults; clones; corals; larvae; population density; spawning;     Show all 8 Subjects
Abstract:
... We are developing techniques to restore coral populations by enhancing larval supply using “artificial spawning hotspots” that aggregate conspecific adult corals. However, no data were available regarding how natural larval supply from wild coral populations is influenced by fertilization rate and how this is in turn affected by local population density and genetic diversity. Therefore, we assesse ...
DOI:
10.1111/rec.12857

19. Manipulation of crossover frequency and distribution for plant breeding

Author:
Blary, A.; Jenczewski, E.
Source:
Theoretical and applied genetics 2019 v.132 no.3 pp. 575-592
ISSN:
0040-5752
Subject:
genetic variation,   etc   ; artificial selection; breeding programs; meiosis; plant breeding;     Show all 5 Subjects
Abstract:
... The crossovers (COs) that occur during meiotic recombination lead to genetic diversity upon which natural and artificial selection can act. The potential of tinkering with the mechanisms of meiotic recombination to increase the amount of genetic diversity accessible for breeders has been under the research spotlight for years. A wide variety of approaches have been proposed to increase CO frequenc ...
DOI:
10.1007/s00122-018-3240-1

20. Exploring and Exploiting Pan-genomics for Crop Improvement

Author:
Tao, Yongfu; Zhao, Xianrong; Mace, Emma; Henry, Robert; Jordan, David
Source:
Molecular plant 2019 v.12 no.2 pp. 156-169
ISSN:
1674-2052
Subject:
genetic variation,   etc   ; bioactive properties; genes; landscapes; single nucleotide polymorphism;     Show all 5 Subjects
Abstract:
... Genetic variation ranging from single-nucleotide polymorphisms to large structural variants (SVs) can cause variation of gene content among individuals within the same species. There is an increasing appreciation that a single reference genome is insufficient to capture the full landscape of genetic diversity of a species. Pan-genome analysis offers a platform to evaluate the genetic diversity of ...
DOI:
10.1016/j.molp.2018.12.016