U.S. flag

An official website of the United States government

Dot gov

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Https

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

PubAg

Main content area

You searched for: Subject "genomics" Remove constraint Subject: "genomics"
Start Over

Search

33,829  Search Results

« Previous | 1 - 20 of 33,829 |
Number of results to display per page

Search Results

1. Modular structure of complex II: An evolutionary perspective

Author:
Val Karavaeva; Filipa L. Sousa
Source:
Biochimica et biophysica acta 2023 v.1864 no.1 pp. 148916
ISSN:
0005-2728
Subject:
genomics,   etc   ; fumarates; oxidoreductases; phylogeny; succinic acid;     Show all 5 Subjects
Abstract:
... Succinate dehydrogenases (SDHs) and fumarate reductases (FRDs) catalyse the interconversion of succinate and fumarate, a reaction highly conserved in all domains of life. The current classification of SDH/FRDs is based on the structure of the membrane anchor subunits and their cofactors. It is, however, unknown whether this classification would hold in the context of evolution. In this work, a lar ...
DOI:
10.1016/j.bbabio.2022.148916

2. Genome-wide DNA methylation analysis of middle-aged and elderly monozygotic twins with age-related hearing loss in Qingdao, China

Author:
Longzi Guo; Weijing Wang; Wanxue Song; Hainan Cao; Huimin Tian; Zhaoguo Wang; Jifeng Ren; Feng Ning; Dongfeng Zhang; Haiping Duan
Source:
Gene 2023 v.849 pp. 146918
ISSN:
0378-1119
Subject:
genomics,   etc   ; DNA methylation; audiometry; computer software; elderly; genes; models; speech; China;     Show all 9 Subjects
Abstract:
... To explore the differences in DNA methylation associated with age-related hearing loss in a study of 57 twin pairs from China. Monozygotic twins were identified through the Qingdao Twin Registration system. The median age of participants was > 50 years. Their hearing thresholds were measured using a multilevel pure-tone audiometry assessment. The pure-tone audiometry was calculated at low frequenc ...
DOI:
10.1016/j.gene.2022.146918

3. Characterization and functional analysis of chicken dsRNA binding protein hnRNPU

Author:
Xifeng Hu; Xiangdong Wu; Zhen Ding; Zheng Chen; Huansheng Wu
Source:
Developmental and comparative immunology 2023 v.138 pp. 104521
ISSN:
0145-305X
Subject:
genomics,   etc   ; DNA; RNA; Vesiculovirus; chickens; cytosol; humans; immunology; nuclear matrix; ribonucleoproteins;     Show all 10 Subjects
Abstract:
... In mammals, heterogeneous ribonucleoprotein U (hnRNPU), also named as nuclear matrix protein-nuclear scaffold attachment factor (SAFA), was originally identified as a DNA/RNA interactor protein. It has been reported that human hnRNPU facilitates IFN-β generation after vesicular stomatitis virus (VSV) infection. Nevertheless, the role of chicken hnRNPU (chhnRNPU) in IFN-β regulation as well as in i ...
DOI:
10.1016/j.dci.2022.104521

4. Biotransformation of sulfamethoxazole by a novel strain, Nitratireductor sp. GZWM139: Characterized performance, metabolic mechanism and application potential

Author:
Mengyu Zhang; Depeng Fan; Chen Su; Luqing Pan; Qili He; Zilu Li; Chang Liu
Source:
Journal of hazardous materials 2023 v.441 pp. 129861
ISSN:
0304-3894
Subject:
genomics,   etc   ; Nitratireductor; antioxidants; biotransformation; cell membranes; cleavage (chemistry); demethylation; hydroxylation; mariculture; nitrogen; oxidation; pH; pollution; sewage; sulfamethoxazole;     Show all 15 Subjects
Abstract:
... A novel strain, Nitratireductor sp. GZWM139 capable of efficient removal of SMX was isolated from mariculture sewage, and Nitratireductor was reported to conduct the removal of antibiotics for the first time. Strain GZWM139 exhibited desirable adaptations to environmental factors with SMX removal efficiencies more than 90 % at temperatures of 28–38 °C, pH values of 4.5–8.5, salinities of 20–30 ‰, ...
DOI:
10.1016/j.jhazmat.2022.129861

5. New insights into lincomycin biodegradation by Conexibacter sp. LD01: Genomics characterization, biodegradation kinetics and pathways

Author:
Huaxin Lei; Jiayu Zhang; Jin Huang; Dengjin Shen; Yin Li; Rui Jiao; Renxin Zhao; Xiaoyan Li; Lin Lin; Bing Li
Source:
Journal of hazardous materials 2023 v.441 pp. 129824
ISSN:
0304-3894
Subject:
genomics,   etc   ; Actinobacteria; activated sludge; ammonium nitrogen; biodegradation; carbon; energy; genome; glucose; lincomycin; logit analysis; nitrogen; oxidation; sodium pyruvate;     Show all 14 Subjects
Abstract:
... The aerobic, lincomycin-degrading bacterial strain Conexibacter sp. LD01, belonging to the phylum Actinobacteria, was isolated from activated sludge. Both second- and third-generation sequencing technologies were applied to uncover the genomic characterization and high-quality genome with 99.2% completeness and 2.2% contamination was obtained. The biodegradation kinetics of lincomycin fit well wit ...
DOI:
10.1016/j.jhazmat.2022.129824

6. Nondestructive and rapid method for sex identification of the tropical sea cucumber Holothuria scabra by anal swab sampling

Author:
Zixuan E; Chuhang Cheng; Feifei Wu; Chunhua Ren; Rong Chen; Yingzhu Rao; Bo Ma; Xiao Jiang; Peng Luo; Xiaomin Li; Xin Zhang; Fajun Jiang; Chaoqun Hu; Ting Chen
Source:
Aquaculture 2023 v.562 pp. 738749
ISSN:
0044-8486
Subject:
genomics,   etc   ; DNA; Holothuria scabra; aquaculture; dimorphism; females; loop-mediated isothermal amplification; males; phenotype; rapid methods; reproduction; South East Asia;     Show all 12 Subjects
Abstract:
... As one of the most economically significant sea cucumber species, Holothuria scabra are naturally distributed in the Indo-West Pacific region and are widely cultural in Southeast Asia. The appearances of female and male H. scabra have no obvious phenotypic dimorphism. Thus, identification of sex-specific markers and establishment of sex detection methods are beneficial to artificially induced repr ...
DOI:
10.1016/j.aquaculture.2022.738749

7. Effective CRISPR/Cas9-based genome editing in large yellow croaker (Larimichthys crocea)

Author:
Qiuhua Li; Guangming Shao; Yangyang Ding; Libing Xu; Jianchun Shao; Jingqun Ao; Xinhua Chen
Source:
Aquaculture and fisheries 2023 v.8 no.1 pp. 26-32
ISSN:
2468-550X
Subject:
genomics,   etc   ; CRISPR-Cas systems; Larimichthys crocea; aquaculture; chorion; disease resistance; genes; genetic improvement; green fluorescent protein; meat quality; mutants; plasmids; survival rate; China;     Show all 14 Subjects
Abstract:
... The large yellow croaker (Larimichthys crocea) is an economically important marine species with the highest annual production among the farmed marine fishes in China. However, the aquaculture industry of this species is suffering from severe problems that include weakened disease resistance, decreased growth rate, and reduced meat quality due to frequent inbreeding. Genome editing, which has a hug ...
DOI:
10.1016/j.aaf.2021.04.008

8. Phage biocontrol of zoonotic food-borne pathogen Vibrio parahaemolyticus for seafood safety

Author:
Jung Hyen Lee; Minjin Oh; Byoung Sik Kim
Source:
Food control 2023 v.144 pp. 109334
ISSN:
0956-7135
Subject:
genomics,   etc   ; Artemia franciscana; Siphoviridae; Vibrio parahaemolyticus; adsorption; bacteriophages; biological control; cell growth; food pathogens; food safety; gastroenteritis; microbial load; multiple drug resistance; pH; seafoods; seawater;     Show all 16 Subjects
Abstract:
... Vibrio parahaemolyticus is a major seafood-borne zoonotic pathogen causing gastroenteritis in humans. Although antibiotics are the most effective chemical agents for V. parahaemolyticus, their abuse has caused the emergence of multidrug-resistant strains, affecting seafood safety. Here, we have isolated and characterized the V. parahaemolyticus bacteriophage VPG01 as an eco-friendly sustainable al ...
DOI:
10.1016/j.foodcont.2022.109334

9. Genome–wide association study and genomic prediction of growth traits in bighead catfish (Clarias macrocephalus Günther, 1864)

Author:
Prapaiphan Chaivichoo; Sila Sukhavachana; Rabuesak Khumthong; Prapansak Srisapoome; Satid Chatchaiphan; Uthairat Na-Nakorn
Source:
Aquaculture 2023 v.562 pp. 738748
ISSN:
0044-8486
Subject:
genomics,   etc   ; Clarias macrocephalus; DNA; aquaculture; body weight; catfish; cost effectiveness; genes; genetic improvement; genetic variance; genome-wide association study; genotyping; heritability; marker-assisted selection; parentage; phenotype; prediction; technology; variance; zinc finger motif;     Show all 20 Subjects
Abstract:
... Next-generation sequencing (NGS) enables cost-effective exploration of genome-wide single nucleotide polymorphisms (SNPs). This new technology has made enormous contributions in various fields including genetic improvement. This study was conducted to identify SNPs that associated with growth traits (body weight, standard length, and total length) of bighead catfish (Clarias macrocephalus Günther, ...
DOI:
10.1016/j.aquaculture.2022.738748

10. Methylome and transcriptome analysis of alters leaf phenotype with autotetraploid in grape

Author:
Xiaodong Xiang; Yukun Gao; Jianghui Cui; Genzeng Ren; Congpei Yin; Jinhua Chang
Source:
Scientia horticulturae 2023 v.307 pp. 111534
ISSN:
0304-4238
Subject:
genomics,   etc   ; 5-methylcytosine; DNA; Vitis vinifera; anthocyanins; antioxidant activity; autotetraploidy; biosynthesis; bisulfites; cell walls; diploidy; epigenetics; gene expression; gene expression regulation; grapes; homeostasis; introns; leaf thickness; leaves; lipid metabolism; methylation; phenotype; photosynthesis; plant hormones; secondary metabolites; transcriptomics;     Show all 26 Subjects
Abstract:
... The doubling of the plant genome causes obvious morphological and physiological changes, and DNA 5-methylcytosine (5mCs) modification is a key epigenetic component that helps neopolyploids overcome challenges and acquire advantages. In the study of autotetraploid grape, we found that leaf thickness, photosynthetic and antioxidant capacity increased and anthocyanin coloring decreased in autotetrapl ...
DOI:
10.1016/j.scienta.2022.111534

11. Inactivation of two SARS-CoV-2 virus surrogates by electron beam irradiation on large yellow croaker slices and their packaging surfaces

Author:
Zonghong Luo; Ke Ni; Yuancheng Zhou; Guanhong Chang; Jiangtao Yu; Chunling Zhang; Wenqi Yin; Dishi Chen; Shuwei Li; Shengyao Kuang; Peng Zhang; Kui Li; Junqing Bai; Xin Wang
Source:
Food control 2023 v.144 pp. 109340
ISSN:
0956-7135
Subject:
genomics,   etc   ; Larimichthys crocea; Porcine epidemic diarrhea virus; RNA; Severe acute respiratory syndrome coronavirus 2; Transmissible gastroenteritis virus; cold chain; color; culture media; decontamination; fish; food safety; irradiation; nonthermal processing; pH; quantitative polymerase chain reaction; risk reduction; total volatile basic nitrogen; transmission electron microscopy; viruses;     Show all 20 Subjects
Abstract:
... The detection of infectious SARS-CoV-2 in food and food packaging associated with the cold chain has raised concerns about the possible transmission pathway of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in foods transported through cold-chain logistics and the need for novel decontamination strategies. In this study, the effect of electron beam (E-beam) irradiation on the inactiv ...
DOI:
10.1016/j.foodcont.2022.109340

12. Special Issue: “Genomics of Stroke”

Author:
Svetlana A. Limborska; Ivan B. Filippenkov
Source:
Genes 2022 v.13 no.3 pp. -
ISSN:
2073-4425
Subject:
genomics,   etc   ; genes; stroke;     Show all 3 Subjects
Abstract:
... Stroke is a multifactorial disease and an extremely serious and socially important medical condition [...] ...
DOI:
10.3390/genes13030415

13. Establishing a blockchain-enabled Indigenous data sovereignty framework for genomic data

Author:
Tim K. Mackey; Alec J. Calac; B S Chenna Keshava; Joseph Yracheta; Krystal S. Tsosie; Keolu Fox
Source:
Cell 2022 v.185 no.15 pp. 2626-2631
ISSN:
0092-8674
Subject:
genomics,   etc   ; blockchain; cells;     Show all 3 Subjects
Abstract:
... Technological advances have enabled the rapid generation of health and genomic data, though rarely do these technologies account for the values and priorities of marginalized communities. In this commentary, we conceptualize a blockchain genomics data framework built out of the concept of Indigenous Data Sovereignty. ...
DOI:
10.1016/j.cell.2022.06.030

14. Compendious survey of protein tandem repeats in inbred mouse strains

Author:
Ahmed Arslan
Source:
BMC genomic data 2022 v.23 no.1 pp. 62
ISSN:
2730-6844
Subject:
genomics,   etc   ; mice; phenotype; surveys;     Show all 4 Subjects
Abstract:
... Short tandem repeats (STRs) play a crucial role in genetic diseases. However, classic disease models such as inbred mice lack such genome wide data in public domain. The examination of STR alleles present in the protein coding regions (are known as protein tandem repeats or PTR) can provide additional functional layer of phenotype regulars. Motivated with this, we analysed the whole genome sequenc ...
DOI:
10.1186/s12863-022-01079-1

15. Genetics of anorexia nervosa: An overview of genome-wide association studies and emerging biological links

Author:
Clara de Jorge Martínez; Gull Rukh; Michael J. Williams; Santino Gaudio; Samantha Brooks; Helgi B. Schiöth
Source:
Journal of genetics and genomics 2022 v.49 no.1 pp. 1-12
ISSN:
1673-8527
Subject:
genomics,   etc   ; anorexia nervosa; comorbidity;     Show all 3 Subjects
Abstract:
... Anorexia nervosa (AN) is a complex disorder with a strong genetic component. Comorbidities are frequent and there is substantial overlap with other disorders. The lack of understanding of the molecular and neuroanatomical causes has made it difficult to develop effective treatments and it is often difficult to treat in clinical practice. Recent advances in genetics have changed our understanding o ...
DOI:
10.1016/j.jgg.2021.09.005

16. Pathogenic variants detected by RNA sequencing in Cornelia de Lange syndrome

Author:
Rie Seyama; Yuri Uchiyama; José Ricard Magliocco Ceroni; Veronica Eun Hue Kim; Isabel Furquim; Rachel Sayuri Honjo; Matheus Augusto Araujo Castro; Lucas Vieira Lacerda Pires; Hiromi Aoi; Kazuhiro Iwama; Kohei Hamanaka; Atsushi Fujita; Naomi Tsuchida; Eriko Koshimizu; Kazuharu Misawa; Satoko Miyatake; Takeshi Mizuguchi; Shintaro Makino; Atsuo Itakura; Débora R. Bertola; Chong Ae Kim; Naomichi Matsumoto
Source:
Genomics 2022 v.114 no.5 pp. 110468
ISSN:
0888-7543
Subject:
genomics,   etc   ; RNA; brain; exons;     Show all 4 Subjects
Abstract:
... Recent studies suggest that transcript isoforms significantly overlap (approximately 60%) between brain tissue and Epstein–Barr virus-transformed lymphoblastoid cell lines (LCLs). Interestingly, 14 cohesion-related genes with variants that cause Cornelia de Lange Syndrome (CdLS) are highly expressed in the brain and LCLs. In this context, we first performed RNA sequencing of LCLs from 22 solved (w ...
DOI:
10.1016/j.ygeno.2022.110468

17. Unlocking plant metabolic diversity: A (pan)-genomic view

Author:
Xuan Zhou; Zhenhua Liu
Source:
Plant communications 2022 v.3 no.2 pp. 100300
ISSN:
2590-3462
Subject:
genomics,   etc   ; biosynthesis; genetic variation;     Show all 3 Subjects
Abstract:
... Plants produce a remarkable diversity of structurally and functionally diverse natural chemicals that serve as adaptive compounds throughout their life cycles. However, unlocking this metabolic diversity is significantly impeded by the size, complexity, and abundant repetitive elements of typical plant genomes. As genome sequencing becomes routine, we anticipate that links between metabolic divers ...
DOI:
10.1016/j.xplc.2022.100300

18. missForest with feature selection using binary particle swarm optimization improves the imputation accuracy of continuous data

Author:
Heejin Jin; Surin Jung; Sungho Won
Source:
Genes & genomics 2022 v.44 no.6 pp. 651-658
ISSN:
1976-9571
Subject:
genomics,   etc   ; algorithms; data collection;     Show all 3 Subjects
Abstract:
... BACKGROUND: Missing data are a common problem in large-scale datasets and its appropriate handling is crucial for data analyses. Missingness can be categorized as (1) missing completely at random (MCAR), (2) missing at random (MAR), and (3) missing not at random (MNAR). Different missingness mechanisms require different imputation strategies. Multiple imputation, an approach for averaging outcomes ...
DOI:
10.1007/s13258-022-01247-8

19. Flip-flop genomics: Charting inversions in the human population

Author:
Sophie Lanciano; Gael Cristofari
Source:
Cell 2022 v.185 no.11 pp. 1811-1813
ISSN:
0092-8674
Subject:
genomics,   etc   ; cells; human population;     Show all 3 Subjects
Abstract:
... Detecting large genomic inversions has long been challenging. In a new study, Porubsky et al. resolve these complex rearrangements in 41 individuals and discover wide regions that undergo recurrent inversions, some of which even toggle back and forth (Porubsky et al., 2022). Many of these regions are associated with genomic disorders. ...
DOI:
10.1016/j.cell.2022.05.002

20. Phylogenetic definitions for 25 higher-level clade names of birds

Author:
George Sangster; Edward L. Braun; Ulf S. Johansson; Rebecca T. Kimball; Gerald Mayr; Alexander Suh
Source:
Avian research 2022 v.13 pp. 100027
ISSN:
2053-7166
Subject:
genomics,   etc   ; birds; phylogeny; research;     Show all 4 Subjects
Abstract:
... Knowledge of the higher-level phylogenetic relationships of birds has grown substantially during the past two decades due to the application of genomic data. However, the nomenclature of higher-level taxa has not become more stable, due to the lack of regulation of taxon names above the level of superfamily by the ICZN, and the usage of rank-based nomenclature, which is not tied to clades in a phy ...
DOI:
10.1016/j.avrs.2022.100027