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genotyping, etc ; Russia; alleles; females; glaucoma; haplotypes; risk; Show all 7 Subjects
Abstract:
... A replicative study of associations of the LOXL1 gene polymorphism with primary open-angle glaucoma (POAG) in the female population of the Central Chernozem region of Russia was performed. The work was done in the design “patients–control.” The study sample consisted of 290 women with POAG and 220 women in the control group. Three polymorphic loci of the LOXL1 gene (rs2165241, rs4886776, rs893818) ...
genotyping, etc ; alleles; blood groups; databases; fluorescence; hemagglutination; Show all 6 Subjects
Abstract:
... Current studies have suggested that the ABO blood group system is associated with several clinical conditions. For large-scale genotyping of ABO alleles, we developed a triplex fluorescence melting curve analysis (FMCA) to determine five single nucleotide variants (SNVs), c.261delG, c.796C>A, c.802G>A and c.803G>C and c.1061delC, responsible for common ABO phenotypes using dual-labeled self-quench ...
genotyping, etc ; agronomy; biodiversity; germplasm; grapes; homonym; vegetative propagation; Show all 7 Subjects
Abstract:
... The cultivated grapevine, Vitis vinifera subsp. vinifera L., is represented by an enormous population of varieties and clones. They arise from the accumulation of gametic and somatic mutations during centuries of sexual and asexual propagation. These varieties represent a vast reservoir of traits/alleles that could be useful in improving the berry quality as well as against environmental stresses. ...
genotyping, etc ; DNA; bacteriology; brucellosis; genetic similarity; genome; vaccines; Show all 7 Subjects
Abstract:
... Brucella sp. are the causative agents of brucellosis. One of the main characteristics of the Brucella genus concerns its very high genetic homogeneity. To date, classical bacteriology typing is still considered as the gold standard assay for direct diagnosis of Brucella. Molecular approaches are routinely used for the identification of Brucella at the genus level. However, genotyping is more compl ...
M. Fernanda Dreccer; Bethany Macdonald; Claire A. Farnsworth; M. Valeria Paccapelo; Mary Anne Awasi; Anthony G. Condon; Kerrie Forrest; Ian Lee Long; C. Lynne McIntyre
genotyping, etc ; cultivars; genetic correlation; germplasm; heritability; phenotype; wheat; Show all 7 Subjects
Abstract:
... KEY MESSAGE: Low-lodging high-yielding wheat germplasm and SNP-tagged novel alleles for lodging were identified in a process that involved selecting donors through functional phenotyping for underlying traits with a designed phenotypic screen, and a crossing strategy involving multiple-donor × elite populations. Lodging is a barrier to achieving high yield in wheat. As part of a study investigatin ...
genotyping, etc ; Measles morbillivirus; genetic variation; genome; monitoring; patients; Show all 6 Subjects
Abstract:
... In an era of decreasing genetic diversity of Measles Virus (MeV), effective surveillance requires a higher-resolution genotyping method or whole genome sequencing (WGS) to document elimination. Through optimization of MeV WGS protocol, we developed a MeV-specific probe enrichment method that allows next generation sequencing from clinical specimens. With the probe enrichment method, 70% of specime ...
genotyping by sequencing, etc ; barley; chromosome mapping; genetic recombination; genomics; Show all 5 Subjects
Abstract:
... As genotyping-by-sequencing (GBS) is widely used in barley genetic studies, the translation of the physical position of GBS-derived SNPs into accurate genetic positions has become relevant. The main aim of this study was to develop a high-resolution consensus linkage map based on GBS-derived SNPs. The construction of this integrated map involved 11 bi-parental populations composed of 3743 segregat ...
genotyping, etc ; agronomy; cucumbers; genomics; phylogeny; single nucleotide polymorphism; transcriptome; Show all 7 Subjects
Abstract:
... Marker-assisted background selection is a powerful molecular tool that can enhance breeding efficiency through the analysis of a large number of markers representing the entire genomic background for precise selection. In the present study, the transcriptomes of 38 cucumber inbred lines with diverse traits were sequenced for single nucleotide polymorphism (SNP) mining for practical application to ...
genotyping, etc ; Giardia lamblia; gastrointestinal diseases; pathogens; pollution; veterinary parasitology; Show all 6 Subjects
Abstract:
... Giardia duodenalis is one of the most common parasitic causes of gastrointestinal illness in humans worldwide with widespread infections in mammalian hosts. It frequently infects cattle, producing a high number of cysts. Cattle can harbor both host-adapted assemblage E and human pathogenic assemblages A and B. Previous studies have demonstrated that conventional molecular methods lack the sensitiv ...
genotyping, etc ; alleles; coronary artery disease; homozygosity; regression analysis; risk factors; Show all 6 Subjects
Abstract:
... Recent genome-wide association studies reported the association of polymorphic alleles of PHACTR1 (rs9349379 (G)), CDDKN2B-AS1 (rs2891168 (G)), COL4A2 (rs11838776 (A)) and SOD2 (rs4880 (T)) with increased risk of coronary artery disease (CAD). The aim of our study was to assess the association of genetic variants with risk of CAD and its severity and in Southeast Iranian population. This study was ...
Silvia de Souza e Silva; Neiva Leite; Lupe Furtado-Alle; Ricardo Lehtonen Rodrigues de Souza; Patricia Ribeiro Paes Corazza; Maiara Cristina Tradiotto; Gerusa Eisfeld Milano; Larissa Rosa da Silva; Juliana Pizzi; Maria de Fátima Aguiar Lopes; Wendell Arthur Lopes; Luciane Viater Tureck
genotyping, etc ; body fat; exercise; gene expression; genes; genotype; longitudinal studies; Show all 7 Subjects
Abstract:
... We aimed to investigate whether the expression levels and polymorphisms in the ADRB2 gene have influenced the anthropometric and cardiometabolic outcomes changes in obese/overweight children submitted to physical exercise programs. This longitudinal study included 197 overweight or obese children aged 10–16 years, submitted to physical exercise programs - three sessions per week for 12 weeks. Anth ...
genotyping, etc ; Rotavirus A; ancestry; evolution; genomics; genotype; infection; monitoring; viruses; Show all 9 Subjects
Abstract:
... Rotavirus A (RVA) G3P[8] is sporadically detected in China, although G9P[8] predominates. To evaluate their genetic composition at the whole-genome level, 24 G3P[8] RVA strains isolated from children under five years were sequenced and characterized. The 24 strains were genotyped as G3-P[8]-I1-R1-C1-M1-A1-N1-T1-E1-H1, indicating the Wa-like genotype constellation. A maximum clade credibility (MCC) ...
genotyping, etc ; Mytilus; chimerism; ecology; evolution; histology; ingestion; mussels; neoplasms; Europe; Show all 10 Subjects
Abstract:
... Transmissible cancers are infectious malignant cell clones that spread among individuals through transfer of living cancer cells. Several such clones have been identified in various species of marine bivalve molluscs, including mussels, clams and cockles. These parasitic cell lineages cause a leukaemia‐like disease called disseminated neoplasia, and are presumed to pass between hosts by ingestion ...
genotyping, etc ; alleles; fever; haplotypes; leptin; leptin receptors; ligases; models; pathogenesis; tuberculosis; Show all 10 Subjects
Abstract:
... The aim of our study was to investigate the association of leptin (LEP) gene (rs11761556, rs12706832, rs2167270), leptin receptor (LEPR) gene (rs1137100, rs1137101, rs1805096) variants and pulmonary tuberculosis (PTB) susceptibility, as well as their several clinical manifestations, in a Chinese population. This study included a cohort of 489 PTB patients and 489 healthy controls, and six SNPs wer ...
genotyping, etc ; Asparagus racemosus; cluster analysis; gardens; genetic variation; genomics; genotype; India; Show all 8 Subjects
Abstract:
... Asparagus racemosus Willd. is an important multipurpose plant, recognized as queen of herbs due to its important medicinal properties. The objective of this study was to contribute to the understanding of A. racemosus genetic diversity by genotyping 20 accessions from ten different agro-ecological zones of Kerala state, India using simple sequence repeat (SSR) markers. A set of 22 SSR markers prev ...
genotyping, etc ; alleles; artificial selection; dissection; genomics; microarray technology; prediction; progeny; soybeans; Show all 9 Subjects
Abstract:
... KEY MESSAGE: We developed the ZDX1 high-throughput functional soybean array for high accuracy evaluation and selection of both parents and progeny, which can greatly accelerate soybean breeding. Microarray technology facilitates rapid, accurate, and economical genotyping. Here, using resequencing data from 2214 representative soybean accessions, we developed the high-throughput functional array ZD ...
Alize Drabbe; Steven Janssens; Sarah Blott; Bart J Ducro; Marie Fontanel; Liesbeth Francois; Anouk Schurink; Anneleen Stinckens; Gabriella Lindgren; Bram Van Mol; Frederik Pille; Nadine Buys; Brandon D. Velie
genotyping, etc ; blood; cell differentiation; chromosomes; hock; horses; osteochondrosis; stifle; veterinary medicine; Show all 9 Subjects
Abstract:
... Osteochondrosis (OC) is an important skeletal disease causing profound welfare concerns in horses. Although numerous studies have explored the genetics underlying OC in various breeds, the Belgian Warmblood (BW) remains unstudied despite having a concerning prevalence of 32.0%. As a result, this study aimed to conduct genome-wide association (GWA) analyses to identify candidate variants associated ...
genotyping, etc ; Holstein; Jersey; alleles; ecotypes; genetic variation; heterozygosity; loci; microsatellite repeats; Show all 9 Subjects
Abstract:
... The application of information-entropy analysis on real data is shown: 84 bulls of Jersey (n = 10), Ayrshire (n = 10), red Danish (n = 10), red Swedish (n = 9) breeds and Holstein ecotypes of German (n = 13), Dutch (n = 17) and North American (n = 15) breeding genotyped by 11 microsatellite loci. The Shannon information index for the combined breed samples was 1.695, the weighted average for the s ...
genotyping, etc ; DNA; databases; genome-wide association study; introns; meat; phenotype; wool; Show all 8 Subjects
Abstract:
... Genome-wide association study (GWAS) is a powerful tool for identifying loci and individual polymorphisms associated with economically important traits in various species of productive animals. The objective of this study was a genome-wide association search in sheep of the North-Caucasian meat and wool breed to identify single nucleotide polymorphisms (SNPs) associated with a class assessment det ...
genotyping, etc ; Holstein; Russia; dairy cattle; genomics; milk; milk yield; models; prediction; Show all 9 Subjects
Abstract:
... Genomic data are widely used in predicting the breeding values of dairy cattle. The accuracy of genomic prediction depends on the size of the reference population and how related the candidate animals are to it. For populations with limited numbers of progeny‐tested bulls, the reference populations must include cows and data from external populations. The aim of this study was to implement state‐o ...