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glucose; glucose transporters, etc ; douchi; gel chromatography; peptides; China; Show all 6 Subjects
Abstract:
... Douchi is a popular soy-fermented food that originated in China with documented hypoglycemic effects. However, the responsible molecules and the mechanism underlying their beneficial effects remain unclear. Therefore, in this study, we aimed to identify the responsible peptide(s) in douchi. A peptide extract of douchi was isolated step-wise by the C₁₈ Sep-Pak technique, size exclusion chromatograp ...
glucose; glucose oxidase, etc ; biomineralization; color; colorimetry; hybrids; mobile telephones; Show all 7 Subjects
Abstract:
... A smartphone-based colorimetric platform for facile glucose detection was constructed below. First, glucose oxidase-Cu₃(PO₄)₂·3H₂O hybrid microflowers (GOx-HMFs) were facilely synthesized via biomineralization, which can react with glucose and 3,3′,5,5′-tetramethylbenzidine to generate colored product. Next, the color information of product was real-time collected and processed via smartphone to r ...
blood glucose; glucose, etc ; glycemic control; hypoglycemia; insulin; polymers; polyols; Show all 7 Subjects
Abstract:
... Diabetic patients with type 1 or advanced type 2 stages need timely and precise insulin injection to regulate the daily blood glucose levels (BGLs). Otherwise, risks of serious or even deadly diabetes-associated complications occur. To achieve prolonged glucose regulation and low hypoglycemia risks, a novel on-demand glucose-responsive glycopolymer system was constructed for insulin delivery, whic ...
... Long and automatic control of blood glucose levels in diabetic patients could solve the problems caused by frequent insulin injections. Herein, we exploited the protection potential of erythrocytes by a “hitchhiking” strategy to significantly prolong the blood circulation time of a specifically-designed smart hitchhiking insulin delivery system (SHIDS). In the SHIDS, insulin, glucose oxidase, and ...
blood glucose; glucose, etc ; blood; blood proteins; fasting; hypoglycemia; juveniles; puppies; Show all 8 Subjects
Abstract:
... The objective of this study was to determine if overnight fasting is associated with hypoglycemia in puppies undergoing elective surgical neutering. One hundred seventy-one apparently healthy puppies between the age of 2 and 6 months presented for elective surgical neutering. Owners were instructed to withhold food from puppies after midnight the night before surgery; water was to be freely availa ...
glucose; glucose transporters, etc ; calcium; fetus; genes; growth and development; pregnancy; trophoblast; Show all 8 Subjects
Abstract:
... Imprinted genes play important regulatory roles in the growth and development of placentas and foetuses during pregnancy. In a previous study, we found that the imprinted gene Neuronatin (NNAT) is involved in foetal development; NNAT expression was significantly lower in the placentas of piglets that died neonatally compared to the placentas of surviving piglets. However, the function and mechanis ...
blood glucose; glucose, etc ; biosensors; blood; diabetes mellitus; humans; insulin; markets; surveys; Show all 9 Subjects
Abstract:
... the work has been aimed to create an overview of available and used methods and ways to determine the concentration of glucose in body fluids, especially from a technical point of view. It also provides an overview of the clinical features of these methods. The survey found that today's market offers a large number of options and approaches to the issue. There are accurate reference laboratory met ...
glucose; glucose tolerance, etc ; humans; meta-analysis; obesity; systematic review; weight loss; Show all 7 Subjects
Abstract:
... The pattern of weight loss and regain, termed “weight cycling,” is common in overweight individuals. It is unclear whether the well‐established benefits of weight loss persist following weight regain or whether weight cycling is harmful. Human studies of weight cycling have conflicting results reflecting limitations of the observational designs of these studies. By controlling the macronutrient co ...
Muhammad Naeem; Sabine Schipf; Robin Bülow; Nicole Werner; Marcus Dörr; Markus M. Lerch; Jens-Peter Kühn; Wolfgang Rathmann; Matthias Nauck; Marcello Ricardo Paulista Markus; Giovanni Targher; Till Ittermann; Henry Völzke
blood glucose; glucose; glucose tolerance, etc ; biomarkers; iron; iron overload; lipid content; magnetism; noninsulin-dependent diabetes mellitus; nutrition; regression analysis; relative risk; Show all 12 Subjects
Abstract:
... While there is evidence that iron overload disorders are associated with type 2 diabetes, the relationship between hepatic iron overload and prediabetes remains unclear. We aimed to investigate the association between hepatic iron overload, as assessed by magnetic resonance imaging (MRI), and different glucose intolerance states in the population-based Study. We included data from 1622 individuals ...
Gilang Gumilar; Joel Henzie; Brian Yuliarto; Aep Patah; Nugraha Nugraha; Muhammad Iqbal; Mohammed A. Amin; Md. Shariar A. Hossain; Yusuke Yamauchi; Yusuf Valentino Kaneti
... Diabetes is a dangerous disease caused by the inability of the body to produce and use insulin properly, resulting in an increase in the blood glucose level. The most advanced technology for glucose detection is the surface plasmon resonance (SPR)-based sensor. However, this technology has a slight drawback due to the small size of glucose. As a porous material, Zr-based UiO-66 MOF has good adsorp ...
Emily Kemp; Tommi Palomäki; Ida A. Ruuth; Zhanna A. Boeva; Teemu A. Nurminen; Risto T. Vänskä; Laura K. Zschaechner; Alejandro García Pérez; Tuuli A. Hakala; Melissa Wardale; Edward Haeggström; Johan Bobacka
glucose; glucose oxidase, etc ; biosensors; chitosan; hydrogels; immobilized enzymes; mass transfer; nanofibers; swine; Show all 9 Subjects
Abstract:
... We integrated a magnetohydrodynamic fluid extractor with an amperometric glucose biosensor to develop a wearable device for non-invasive glucose monitoring. Reproducible fluid extraction through the skin and efficient transport of the extracted fluid to the biosensor surface are prerequisites for non-invasive glucose monitoring. We optimized the enzyme immobilization and the interface layer betwee ...
glucose; glucose-6-phosphatase, etc ; absorption; catabolism; diabetes mellitus; insulin; insulin resistance; mortality; phytochemicals; Show all 9 Subjects
Abstract:
... Diabetes mellitus is the most well-known endocrine dilemma suffered by hundreds of million people globally, with an annual mortality of more than one million people. This high mortality rate highlights the need for in-depth study of anti-diabetic agents. This review explores the phytochemical contents and anti-diabetic mechanisms of M. charantia (cucurbitaceae). Studies show that M. charantia cont ...
glucose; glucose oxidase, etc ; biocompatible materials; catalase; homeostasis; manganese; mitochondria; neoplasms; platinum; starvation; therapeutics; Show all 11 Subjects
Abstract:
... Endogenous H₂O₂ sacrifices for diversified therapeutic reactions against tumor. However, the treatment outcome is not always satisfactory owing to the unsustainable H₂O₂ supply from tumor microenvironment (TME). Herein, a platinum (Pt) nanourchin-based multi-enzymatic platform (referred to PGMA) is established by surface conjugation of glucose oxidase (GOx) capped with manganese carbonyl (MnCO) an ...
... Both in nature and in aquaculture, fish may experience periods of food scarcity or hunger. The metabolic regulation of fish when nutritional state changes is a complex process that involves many factors. To study glucose metabolism adaptability during fasting and re-feeding in the black carp (Mylopharyngodon piceus), we measured changes in some biochemical indicators related to glucose metabolism. ...
... Flaxseed has displayed the potential beneficial as functional foods. However, most studies focused on effects of flaxseed extracts or ingredients in flaxseed. Besides, few studies showed that flaxseed extracts contributed to anti-type 1 diabetes (T1D), yet the underlying mechanism is still unknown. In the present study, 16.7% of milled flaxseed (MF)-added diet was given to diabetic mice induced by ...
glucose; glucose oxidase, etc ; biofuels; catalase; catalytic activity; drugs; irradiation; nanospheres; organosilicon compounds; porous media; Show all 10 Subjects
Abstract:
... As one of the most important parameters of the nanomotors’ motion, precise speed control of enzyme-based nanomotors is highly desirable in many bioapplications. However, owing to the stable physiological environment, it is still very difficult to in situ manipulate the motion of the enzyme-based nanomotors. Herein, inspired by the brakes on vehicles, the near-infrared (NIR) “optical brakes” are in ...
Paola Valero; Rodrigo Salas; Fabián Pardo; Marcelo Cornejo; Gonzalo Fuentes; Sofía Vega; Adriana Grismaldo; Jan-Luuk Hillebrands; Eline M. van der Beek; Harry van Goor; Luis Sobrevia
blood glucose; glucose, etc ; fetus; gestational diabetes; hyperglycemia; hypoglycemia; neonates; pregnancy outcome; time series analysis; Show all 9 Subjects
Abstract:
... Pregnant women may develop gestational diabetes mellitus (GDM), a disease of pregnancy characterised by maternal and fetal hyperglycaemia with hazardous consequences to the mother, the fetus, and the newborn. Maternal hyperglycaemia in GDM results in fetoplacental endothelial dysfunction. GDM-harmful effects result from chronic and short periods of hyperglycaemia. Thus, it is determinant to keep g ...
glucose; glucose oxidase, etc ; absorption; cancer therapy; catalytic activity; fever; glutathione; green chemistry; neoplasms; polyvinylpyrrolidone; Show all 10 Subjects
Abstract:
... Nanocatalytic therapy is an emerging strategy for combating various malignant tumors, which is limited by acid/H₂O₂ deficiency and overexpressed glutathione (GSH). Herein, the versatile MoO₃–ₓ@Fe₃O₄-GOD-PVP (MFGP) nanoreactors were developed to overcome the limitations of nanocatalytic therapy. First, MoO₃–ₓ nanoflakes were loaded with Fe₃O₄ nanozymes via electrostatic self-assembly and then decor ...
blood glucose; glucose, etc ; adipocytes; adipose tissue; glycolysis; lactate dehydrogenase; protein degradation; research; tissue weight; Show all 9 Subjects
Abstract:
... Plasma glucose levels are homeostatically regulated within strict boundaries and are maintained through a balance between peripheral glucose uptake and hepatic glucose production. However, little is known about the regulatory mechanism of glucose uptake in adipocytes during fasting. Under fasting conditions, the expression levels of 8 glycolytic enzymes were significantly reduced in adipose tissue ...
blood glucose; glucose, etc ; biosensors; blood; detection limit; electrical conductivity; electrochemistry; humans; physical activity; sweat; Show all 10 Subjects
Abstract:
... Continuous painless glucose monitoring is the greatest desire of more than 422 million diabetics worldwide. Therefore, new non-invasive and convenient approaches to glucose monitoring are more in demand than other tests for microanalytical diagnostic tools. Besides, blood glucose detection can be replaced by continuous glucose monitoring of other human biological fluids (e.g. sweat) collected non- ...