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You searched for: Subject "heat shock proteins" Remove constraint Subject: "heat shock proteins"
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1. Exposing the Brain Proteomic Signatures of Alzheimer’s Disease in Diverse Racial Groups: Leveraging Multiple Data Sets and Machine Learning

Author:
Heather Desaire; Kaitlyn E. Stepler; Renã A. S. Robinson
Source:
Journal of proteome research 2022 v.21 no.4 pp. 1095-1104
ISSN:
1535-3907
Subject:
heat shock proteins,   etc   ; biomarkers; brain; proteome; proteomics; research;     Show all 6 Subjects
Abstract:
... Recent studies have highlighted that the proteome can be used to identify potential biomarker candidates for Alzheimer’s disease (AD) in diverse cohorts. Furthermore, the racial and ethnic background of participants is an important factor to consider to ensure the effectiveness of potential biomarkers for representative populations. A promising approach to survey potential biomarker candidates for ...
DOI:
10.1021/acs.jproteome.1c00966

2. Specific locations and amounts of denatured collagen and collagen-specific chaperone HSP47 in the oviducts and uteri of old cows as compared with those of heifers

Author:
Raihana Nasrin Ferdousy; Hiroya Kadokawa
Source:
Reproduction, fertility, and development 2022 v.34 no.8 pp. 619-632
ISSN:
1031-3613
Subject:
heat shock proteins,   etc   ; collagen; fibroblasts; fibrosis; fluorescence; immunohistochemistry;     Show all 6 Subjects
Abstract:
... Collagen, the most abundant extra-cellular matrix in oviducts and uteri, performs critical roles in pregnancies. We hypothesised that the locations and amounts of both denatured collagen and the collagen-specific molecular chaperone 47-kDa heat shock protein (HSP47) in the oviducts and uteri of old cows are different compared with those of young heifers because of repeated pregnancies. Since detec ...
DOI:
10.1071/RD21130

3. GWAS Reveal Novel Sex-Related Markers and Candidate Genes in Sea Urchin Mesocentrotus nudus

Author:
Quanchao Wang; Ying Liu; Yanxia Wang; Shaoyu Jiang; Chuanxin Zhang; Baoquan Li
Source:
Marine biotechnology 2022 v.24 no.1 pp. 32-39
ISSN:
1436-2228
Subject:
heat shock proteins,   etc   ; Mesocentrotus; biotechnology; mariculture; mitochondria; sex determination; transcriptome;     Show all 7 Subjects
Abstract:
... Mesocentrotus nudus is an economically important mariculture species. Identification of sex-related markers and candidate genes has potential implications for sex-control breeding of Mesocentrotus nudus. The aim of this study was to identify the molecular markers and genes associated with the sex of M. nudus. Initial GWAS analysis based on 80 individuals genotyped by using GBS identified 22 sex-re ...
DOI:
10.1007/s10126-021-10084-x

4. Cascade-responsive nano-assembly for efficient photothermal-chemo synergistic inhibition of tumor metastasis by targeting cancer stem cells

Author:
Xianqi Zhu; Lin Li; Jin Tang; Chunyu Yang; Hao Yu; Kunpeng Liu; Ziyan Zheng; Xinggui Gu; Qingsong Yu; Fu-Jian Xu; Zhihua Gan
Source:
Biomaterials 2022 v.280 pp. 121305
ISSN:
0142-9612
Subject:
heat shock proteins,   etc   ; biocompatible materials; chitosan; cytotoxicity; drugs; metastasis; neoplasms; peptides; therapeutics;     Show all 9 Subjects
Abstract:
... Metastasis has been widely recognized as the most lethal threats for cancer patients. Due to their special genetic and environmental context, cancer stem cells (CSCs) which are resistant to most cytotoxic drugs and radiation, are considered as the dominant culprit for metastasis. Thus, the efficient targeting and thorough elimination of CSCs are significantly urgent for the enhancement of therapeu ...
DOI:
10.1016/j.biomaterials.2021.121305

5. Effects of salinity changes on the osmoregulatory and stress responses in the bay scallop Argopecten irradians

Author:
Jin Ah Song; Young Jae Choi; Cheol Young Choi
Source:
Fisheries science 2022 v.88 no.2 pp. 275-283
ISSN:
0919-9268
Subject:
heat shock proteins,   etc   ; Argopecten irradians; apoptosis; gene expression; glucose; hemolymph; saline water; salinity;     Show all 8 Subjects
Abstract:
... Most marine mollusks exhibit osmoregulatory mechanisms to cope with hypo- or hyperosmotic stress. In the present study, we elucidated the effects of exposure to hyposmotic and hyperosmotic stress on bay scallop Argopecten irradians. The Na⁺, K⁺, and Cl⁻ ions of bay scallop hemolymph traversed in a similar direction as that of surrounding salinity. Moreover, the gill Na⁺/K⁺-ATPase was affected by c ...
DOI:
10.1007/s12562-022-01586-1

6. Interaction of constituents of MDT regimen for leprosy with Mycobacterium leprae HSP18: impact on its structure and function

Author:
Ayon Chakraborty; Rajesh Ghosh; Ashis Biswas
Source:
FEBS journal 2022 v.289 no.3 pp. 832-853
ISSN:
1742-464X
Subject:
heat shock proteins,   etc   ; Mycobacterium leprae; antigens; dapsone; hydrophobicity; leprosy; rifampicin; stoichiometry; therapeutics; thermal stability; tryptophan;     Show all 11 Subjects
Abstract:
... Mycobacterium leprae, the causative organism of leprosy, harbors many antigenic proteins, and one such protein is the 18‐kDa antigen. This protein belongs to the small heat shock protein family and is commonly known as HSP18. Its chaperone function plays an important role in the growth and survival of M. leprae inside infected hosts. HSP18/18‐kDa antigen is often used as a diagnostic marker for de ...
DOI:
10.1111/febs.16212

7. Ocean warming lead to heat shock protein expression and decrease in the feeding rate of the Patagonian sea star Anasterias minuta

Author:
Lorena P. Arribas; José E.F. Alfaya; M. Gabriela Palomo; Sebastian Giulianelli; Rocío A. Nieto Vilela; Gregorio Bigatti
Source:
Journal of experimental marine biology and ecology 2022 v.546 pp. 151661
ISSN:
0022-0981
Subject:
heat shock proteins,   etc   ; heat stress; littoral zone; protein synthesis; salinity; species diversity; water temperature; Argentina;     Show all 8 Subjects
Abstract:
... Climate change has consequences over marine organisms and their behavior. Echinoderms have been found to be negatively affected on righting time, survival, feeding rate or growth by high temperatures, low salinity or their interaction. We analyzed the effects of temperature and salinity fluctuation under a climate change scenario on feeding rate, righting time and heat shock proteins (Hsp70) expre ...
DOI:
10.1016/j.jembe.2021.151661

8. Small Heat Shock Protein’s Gene Expression Response to Iron Oxide Nanoparticles in the Brain

Author:
Mehdi Basaki; Kamran Keykavusi; Nazila Sahraiy; Ghasem Akbari; Marzieh Hejazi
Source:
Biological trace element research 2022 v.200 no.4 pp. 1791-1798
ISSN:
0163-4984
Subject:
heat shock proteins,   etc   ; chick embryos; eggs; gene expression; heat stress; iron oxides; models; research; stress response;     Show all 9 Subjects
Abstract:
... Small heat shock proteins (SHSPs) are conserved proteins that participate in many cellular functions like preventing protein aggregation and stress response. However, their role in responding to nanoparticles (NPs) has not yet been explained. We used a chicken embryo model to investigate the effects of two different forms of iron oxide-NPs (IONPs) on the mRNA expression of HSPB1, HSPB5, HSPB8, and ...
DOI:
10.1007/s12011-021-02761-8

9. Genetic and Clinical Studies of Peripheral Neuropathies with Three Small Heat Shock Protein Gene Variants in Korea

Author:
Si On Lim; Na Young Jung; Ah Jin Lee; Hee Ji Choi; Hye Mi Kwon; Wonseok Son; Soo Hyun Nam; Byung-Ok Choi; Ki Wha Chung
Source:
Genes 2022 v.13 no.3 pp. -
ISSN:
2073-4425
Subject:
heat shock proteins,   etc   ; cohort studies; genes; heat stress; heterozygosity; nerve tissue; patients; peripheral nervous system diseases; Korean Peninsula;     Show all 9 Subjects
Abstract:
... Small heat shock proteins (sHSPs) are ATP-independent chaperones that help correct the folding of denatured proteins and protect cells from stress. Mutations in HSPB1, HSPB8, and HSPB3 are implicated in inherited peripheral neuropathies (IPNs), such as Charcot-Marie-Tooth disease type 2 (CMT2) and distal hereditary motor neuropathies (dHMN). This study, using whole exome sequencing or targeted gen ...
DOI:
10.3390/genes13030462

10. 3-Indoleacrylic acid from canola straw as a promising antialgal agent - Inhibition effect and mechanism on bloom-forming Prorocentrum donghaiense

Author:
Kokoette Effiong; Jing Hu; Caicai Xu; Yiyi Zhang; Shumiao Yu; Tao Tang; Yuzhou Huang; Yongliang Lu; Wei Li; Jiangning Zeng; Xi Xiao
Source:
Marine pollution bulletin 2022 v.178 pp. 113657
ISSN:
0025-326X
Subject:
heat shock proteins,   etc   ; Prorocentrum; canola; cytochrome f; marine pollution; photosynthesis; poisonous algae; reactive oxygen species; rhodopsin; straw; transcription (genetics);     Show all 11 Subjects
Abstract:
... Harmful algal blooms (HABs) have induced severe damage worldwide. A novel high-efficient antialgal natural chemical, 3-indoleacrylic acid (3-IDC) with a 5-day half-maximal inhibitory concentration (IC₅₀, ₅d), was discovered from canola straw, and its algal inhibition mechanism was investigated. Adverse effects were observed on the growth of P. donghaiense with 3-IDC addition, following an increase ...
DOI:
10.1016/j.marpolbul.2022.113657

11. Classifying the superfamily of small heat shock proteins by using g-gap dipeptide compositions

Author:
Pengmian Feng; Weiwei Liu; Cong Huang; Zhaohui Tang
Source:
International journal of biological macromolecules 2021 v.167 pp. 1575-1578
ISSN:
0141-8130
Subject:
heat shock proteins,   etc   ; dipeptides; heat stress; humans;     Show all 4 Subjects
Abstract:
... Small heat shock protein (sHSP) is a superfamily of molecular chaperone and is found from archaea to human. Recent researches have demonstrated that sHSPs participate in a series of biological processes and are even closely associated with serious diseases. Since sHSP is a very large superfamily and members from different superfamilies exhibit distinct functions, accurate classification of the sub ...
DOI:
10.1016/j.ijbiomac.2020.11.111

12. STAY-GREEN and light-harvesting complex II chlorophyll a/b binding protein are involved in albinism of a novel albino tea germplasm ‘Huabai 1’

Author:
Xuefei Chen; Jianjie Li; Ying Yu; Xiaobing Kou; Rajiv Periakaruppan; Xuan Chen; Xinghui Li
Source:
Scientia horticulturae 2022 v.293 pp. 110653
ISSN:
0304-4238
Subject:
heat shock proteins,   etc   ; albino; chlorophyll; chloroplasts; germplasm; leaves; light harvesting complex; photosynthesis; tea; transmission electron microscopy; two hybrid system techniques;     Show all 11 Subjects
Abstract:
... ‘Huabai 1’ is a new albino tea germplasm, with high amino acids in its albinism period, however, the albino mechanism remains unknown. To understand the albinism mechanism of ‘Huabai 1’, molecular-level studies were carried out to reveal the functions of CsLHCII and CsSGR in albinism. In this study, transmission electron microscopy (TEM) observations revealed that albino leaves of ‘Huabai 1’ are m ...
DOI:
10.1016/j.scienta.2021.110653

13. The BRCA2 missense mutation K2497R suppressed self-degradation and increased ATP production and cell proliferation

Author:
Gerelmaa Enkhbat; Akira Nakanishi; Yoshio Miki
Source:
Biochemical and biophysical research communications 2022 v.590 pp. 27-33
ISSN:
0006-291X
Subject:
heat shock proteins,   etc   ; breast neoplasms; cell proliferation; centrosomes; cycloheximide; cytokinesis; genes; interphase; lysine; missense mutation; research; tumor suppressor proteins; ubiquitination;     Show all 13 Subjects
Abstract:
... Breast cancer susceptibility gene 2 (BRCA2) mediates genome maintenance during the S phase of the cell cycle, with important roles in replication stress, centrosome replication, and cytokinesis. In this study, we showed that a small heat shock protein, HSP27, interacted with and participated in the degradation of BRCA2 in estrogen-treated MCF-7 cells. BRCA2 degradation reportedly requires ubiquiti ...
DOI:
10.1016/j.bbrc.2021.12.073

14. Ecotoxicological assessment of spent battery extract using zebrafish embryotoxicity test: A multi-biomarker approach

Author:
Wen-Qian Wang; Hao-Hao Chen; Wen-Jun Zhao; Ke-Ming Fang; Hong-Jie Sun; Feng-Yun Zhu
Source:
Chemosphere 2022 v.287 pp. 132120
ISSN:
0045-6535
Subject:
heat shock proteins,   etc   ; Danio rerio; batteries; body length; ecotoxicology; embryotoxicity; heart rate; metallothionein; oxidative stress; pollution; risk; survival rate; transcription (genetics);     Show all 13 Subjects
Abstract:
... Water environmental pollution caused by spent batteries is a nonignorable environmental issue. In this study, the early life stage of zebrafish was employed to assess the environmental risk of spent batteries after exposure to 0, 1%, 2%, 5% and 10% spent battery extract for 120 h. Our results clearly indicated that spent battery extract can significantly decrease the survival rate, hatching rate a ...
DOI:
10.1016/j.chemosphere.2021.132120

15. Photothermal therapy may be a double-edged sword by inducing the formation of bacterial antibiotic tolerance

Author:
Yun Qiu; Shimin Yu; Yulan Wang; Leyi Xiao; Linsen Pei; Yingying Pu; Yufeng Zhang
Source:
Biomaterials science 2022 v.10 no.8 pp. 1995-2005
ISSN:
2047-4849
Subject:
heat shock proteins,   etc   ; antibiotic resistance; antibiotics; bacteria; biocompatible materials; cell membranes; electron transport chain; gold; heat stress; infectious diseases; photothermotherapy; shrinkage;     Show all 12 Subjects
Abstract:
... Photothermal nanoparticles are thought to be the most suitable candidates against infectious disease by disrupting the cell membrane or inhibiting cellular metabolism. However, cells with low-metabolic activity states may be endowed with greater ability against harsh environments including antibiotic treatment. For now, it remains unexplored whether and how photothermal therapy (PTT) gives rise to ...
DOI:
10.1039/d1bm01740c

16. Semiconducting polymer nanoparticles for NIR-II fluorescence imaging-guided photothermal/thermodynamic combination therapy

Author:
Wenqi Wang; Xi Zhang; Xiaoyue Ni; Wen Zhou; Chen Xie; Wei Huang; Quli Fan
Source:
Biomaterials science 2022 v.10 no.3 pp. 846-853
ISSN:
2047-4849
Subject:
heat shock proteins,   etc   ; biocompatible materials; cancer therapy; composite polymers; electrostatic interactions; fluorescence; heat; irradiation; neoplasms; phototherapy; photothermotherapy; precision medicine; semiconductors; temperature;     Show all 14 Subjects
Abstract:
... Photothermal therapy is a promising phototherapeutic modality that has been widely studied in cancer therapy. However, because of the influence of heat shock protein (HSP), the therapeutic efficacy of photothermal therapy (PTT) is significantly suppressed. To improve the therapeutic efficacy, different tumor-specific therapeutic modalities have been chosen to combine with PTT. However, most of the ...
DOI:
10.1039/d1bm01646f

17. Validamycin A Enhances the Interaction Between Neutral Trehalase and 14-3-3 Protein Bmh1 in Fusarium graminearum

Author:
Li Ren; Yi-Ping Hou; Yuan-Ye Zhu; Fei-Fei Zhao; Ya-Bing Duan; Luo-Yu Wu; Xiao-Xin Duan; Jie Zhang; Ming-Guo Zhou
Source:
Phytopathology 2022 v.112 no.2 pp. 290-298
ISSN:
0031-949X
Subject:
heat shock proteins,   etc   ; Fusarium graminearum; Saccharomyces cerevisiae; coleoptiles; deoxynivalenol; enzyme activation; fungicides; glycerol; hyphae; plant pathology; precipitin tests; toxicology; trehalase; virulence; wheat;     Show all 15 Subjects
Abstract:
... In agriculture, Trehalase is considered the main target of the biological fungicide validamycin A, and the toxicology mechanism of validamycin A is unknown. 14-3-3 proteins, highly conserved proteins, participate in diverse cellular processes, including enzyme activation, protein localization, and acting as a molecular chaperone. In Saccharomyces cerevisiae, the 14-3-3 protein Bmh1could interact w ...
DOI:
10.1094/PHYTO-05-21-0214-R

18. Cu-Chelated polydopamine nanoparticles as a photothermal medium and “immunogenic cell death” inducer for combined tumor therapy

Author:
Na Xu; Ao Hu; Ximing Pu; Juan Wang; Xiaoming Liao; Zhongbing Huang; Guangfu Yin
Source:
Journal of materials chemistry B 2022 v.10 no.16 pp. 3104-3118
ISSN:
2050-7518
Subject:
heat shock proteins,   etc   ; adjuvants; artificial intelligence; cell death; chemical bonding; death; folic acid; immune response; irradiation; metastasis; neoplasm cells; neoplasms; photothermotherapy; temperature; toxicity;     Show all 15 Subjects
Abstract:
... Chemodynamic therapy (CDT) and photothermal therapy (PTT) have been powerful technologies for tumor ablation. However, how to realize efficient CDT and PTT synergetic tumor ablation through a safe and intelligent system, remains a topic of great research value. Herein, a novel Cu-chelated polydopamine nano-system (Cu–PDA) with surface PEGylation and folate (FA) targeting modification (Cu–PDA–FA) w ...
DOI:
10.1039/d2tb00025c

19. Morphological Peculiarities of Parasitic (Trichosomoides crassicauda) Infection in Rat Urinary Bladder

Author:
Vladyslav Sikora; Mycola Lуndіn; Natalia Hyriavenko; Roman Moskalenko; Yulia Lуndіna; Kateryna Sikora; Ruslana Chyzhma; Olena Diachenko; Anatolii Romaniuk
Source:
Macedonian veterinary review 2021 v.44 no.2 pp. 159-167
ISSN:
1857-7415
Subject:
heat shock proteins,   etc   ; bladder; helminths; immunohistochemistry; males; prediction; rats; urine;     Show all 8 Subjects
Abstract:
... Trichosomoides crassicauda (T. crassicauda) is a parasite commonly localized in the urinary bladder (UB) of laboratory and wild rats. The presence of these helminths can influence the prediction of pathological changes in the UB. Therefore, the purpose of this research was to make a comprehensive study of the features of the morphological changes in the UB wall of white laboratory rats as a result ...
DOI:
10.2478/macvetrev-2021-0019

20. Effect of temperature on the toxicokinetics and gene expression of the pacific cupped oyster Crassostrea gigas exposed to cadmium

Author:
Ming Sun; Fanguang Hu; Tianming Wang; Tianwen Zhang; Yuanyuan Jing; Wen Guo; Qun Chen; Guangbin Liu
Source:
Comparative biochemistry and physiology 2022 v.253 pp. 109252
ISSN:
1532-0456
Subject:
heat shock proteins,   etc   ; Crassostrea gigas; P-glycoproteins; atomic absorption spectrometry; bioaccumulation; cadmium; chemical analysis; depuration; gene expression; half life; metallothionein; models; oysters; pharmacokinetics; temperature;     Show all 15 Subjects
Abstract:
... In this study, we investigated the influence of temperature on the bioaccumulation and depuration of Crassostrea gigas exposed to Cd associated with its molecular responses. Oysters were acclimatized to different temperatures (10 °C, 15 °C, 20 °C, 25 °C, and 30 °C) for 14 d and then exposed to 10 μg/L Cd for 28 d, followed by a depuration period of 35 d. Oysters were sampled for chemical analysis ...
DOI:
10.1016/j.cbpc.2021.109252