An official website of the United States government
Here’s how you know
Official websites use .gov
A .gov website belongs to an official government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.
... The aim of this work is to study the immune responses of the polychaete Sabella spallanzanii after exposure to copper sulphate, an immunomodulating agent in marine organisms, and the multiple stresses caused by Escherichia coli infection, to validate the species as a model organism in marine-coastal biomonitoring programmes. Polychaetes were housed in laboratory and divided into five experimental ...
... Children are an important target group for influenza vaccination, but few studies have prospectively evaluated influenza vaccine efficacy (VE) in children under 3 years of age. This was a randomized Phase III trial to assess the efficacy, immunogenicity, and safety of an inactivated quadrivalent influenza vaccine (QIV) in young children (EudraCT: 2016–004904–74). Influenza-naïve children aged 6–35 ...
hemagglutination tests, etc ; hemolysis; intravenous injection; Show all 3 Subjects
Abstract:
... Hemolytic reactions can cause serious complications after administration of Intravenous Immunoglobulin (IVIG), due to passive transfer of anti-A and anti-B IgG antibodies (isoagglutinins). A maximum allowable amount of isoagglutinins is established in the US and EU for licensed IVIG, as measured by a specified direct hemagglutination test (DHAT). Despite this limit, reports of hemolysis have incre ...
hemagglutination, etc ; alleles; blood groups; databases; fluorescence; genotyping; Show all 6 Subjects
Abstract:
... Current studies have suggested that the ABO blood group system is associated with several clinical conditions. For large-scale genotyping of ABO alleles, we developed a triplex fluorescence melting curve analysis (FMCA) to determine five single nucleotide variants (SNVs), c.261delG, c.796C>A, c.802G>A and c.803G>C and c.1061delC, responsible for common ABO phenotypes using dual-labeled self-quench ...
hemagglutination, etc ; descriptive studies; geometry; immunogenicity; influenza; influenza vaccines; seroconversion; Taiwan; Show all 8 Subjects
Abstract:
... High-dose influenza vaccine offers better protection against influenza/associated complications compared with standard-dose formulation. We evaluated immunogenicity and safety of high-dose influenza vaccine (QIV-HD) and standard-dose (QIV-SD) in older adults (≥65 years) in Taiwan. This was a phase III, randomized, modified double-blind, active-controlled, multi-center, descriptive study in older a ...
Artur Capão; Maria L. Aguiar-Oliveira; Braulia C. Caetano; Thayssa K. Neves; Paola C. Resende; Walquiria A. F. Almeida; Milene D. Miranda; Olindo A.ssis Martins-Filho; David Brown; Marilda M. Siqueira; Cristiana C. Garcia
hemagglutination, etc ; antibodies; immunogenicity; influenza; influenza vaccines; mutation; seroconversion; vaccination; Brazil; Show all 9 Subjects
Abstract:
... Annual vaccination against influenza is the best tool to prevent deaths and hospitalizations. Regular updates of trivalent inactivated influenza vaccines (TIV) are necessary due to high mutation rates in influenza viruses. TIV effectiveness is affected by antigenic mismatches, age, previous immunity, and other host factors. Studying TIV effectiveness annually in different populations is critical. ...
hemagglutination, etc ; azides; cycloaddition reactions; lectins; ligands; mannose; moieties; research; triazoles; Show all 9 Subjects
Abstract:
... Two families (A, B) of triazole conjugates derived from d-mannose possessing reversed linkage functionality were easily assembled by Cu(I) catalyzed azide-alkyne cycloaddition reaction (CuAAC). The mannose precursors were built with either 3-azidopropyl or propargyl aglycones whereas the phenyl moieties were built with terminal azide or propargyl groups, respectively. In a hemagglutination inhibit ...
hemagglutination, etc ; Japan; antibodies; antigens; blood serum; cross immunity; influenza; influenza vaccines; Show all 8 Subjects
Abstract:
... In Japan, inactivated influenza vaccines are used. We measured titers of antibodies to vaccine strains of three influenza types—influenza A (H1N1), influenza A (H3N2), and influenza B/Victoria—from the 2017/2018 to 2021/2022 seasons, but not for influenza A (H3N2) from the 2018/2019 season, using a single set of serum samples from 34 healthy volunteers, and assessed the consistency in antibody pos ...
... A total of 1007 samples (910 fecal droplets and 97 cloacal swabs) were collected from 14 species of migratory wild birds in most wetlands during 3 successive migration seasons from September to March (2015–2018) in Southern Egypt. The samples were propagated in embryonated chicken eggs and positive allantoic fluids by hemagglutination test were tested for Newcastle disease virus (NDV) and avian in ...
hemagglutination, etc ; Penicillium oxalicum; acid hydrolysis; bioactive properties; galactomannans; galectins; interferometry; methylation; therapeutics; Show all 9 Subjects
Abstract:
... Polysaccharides from fungi have many bioactivities. Previous studies showed that galactomannans from Penicillium oxalicum antagonize galectin-8-mediated activity. Here, two intracellular and two extracellular galactomannans were purified and their structures were comparatively characterized by NMR, partial acid hydrolysis and methylation. All four of them were identified to be galactomannans with ...
hemagglutination, etc ; Lagovirus; adaptive immunity; coagulation; microscopy; phagocytosis; spectroscopy; veterinary medicine; viral hepatitis; Show all 9 Subjects
Abstract:
... Lagovirus europaeus/GI.1 causes a fatal viral condition in rabbits characterized by acute viral hepatitis and disseminated intravascular coagulation. Due to rapid viral and environmental changes variants (Lagovirus europaeus/GI.1a and GI.2) have appeared and few immunological studies were performed. The aim of the study was to determine innate and adaptive immunity parameters in rabbits infected w ...
hemagglutination, etc ; Panulirus argus; antibiotics; aquaculture; hemocytes; histology; immune system; inoculum; monophenol monooxygenase; viruses; Show all 10 Subjects
Abstract:
... Experimental infections have been used to better comprehend the immune system of organisms, and to probe for additives that generate greater resistance and help reduce antibiotic use in aquaculture. We compared the immune response of juveniles of the Caribbean spiny lobster, Panulirus argus, infected naturally with Panulirus argus virus 1 (PaV1) versus organisms infected experimentally, to determi ...
hemagglutination, etc ; antibodies; blood serum; cohort studies; confidence interval; influenza; pandemic; public health; vaccination; Taiwan; Show all 10 Subjects
Abstract:
... The objective of this study was to evaluate the effects of prior-infection and repeated vaccination on post-vaccination antibody titers. A(H1N1)pdm09 strain was included in 2009 pandemic monovalent, 2010–2011, and 2011–2012 trivalent influenza vaccines (MIVpdm09, TIV10/11, TIV11/12) in Taiwan. During the 2011–2012 influenza season, we conducted a prospective sero-epidemiological cohort study among ...
hemagglutination, etc ; animal ecology; haptoglobins; hemolysis; immune system; longitudinal studies; probability; reproductive performance; seabirds; viability; Show all 10 Subjects
Abstract:
... Longitudinal studies of various vertebrate populations have demonstrated senescent declines in reproductive performance and survival probability to be almost ubiquitous. Longitudinal studies of potential underlying proximate mechanisms, however, are still scarce. Due to its critical function in the maintenance of health and viability, the immune system is among the potential (mediators of) proxima ...
hemagglutination, etc ; B-lymphocytes; T-lymphocytes; adjuvants; antibodies; biomarkers; influenza; interleukin-21; vaccination; vaccines; viruses; Show all 11 Subjects
Abstract:
... Unadjuvanted A/H7N9 vaccines are poorly immunogenic. The immune response is improved with the addition of MF59, an oil-in-water adjuvant. However, the cellular immunologic responses of MF59-adjuvanted A/H7N9 vaccine are not fully understood. 37 participants were vaccinated with 2 doses of 2013 influenza A/H7N9 vaccine (at Days 1 and 21) with or without MF59 and enrolled in an immunology substudy. ...
hemagglutination, etc ; Infectious bronchitis virus; body temperature; chickens; genes; infectious bronchitis; vaccination; vaccines; Saudi Arabia; Show all 9 Subjects
Abstract:
... Infectious bronchitis virus (IBV) has been frequently reported in chickens worldwide, including in the Eastern Region of Saudi Arabia (ERS). Several IBV outbreaks were recently reported in chickens despite the massive use of various vaccines. Based on partial sequencing of the S1 gene, at least three genotypes were reported (CK/CH/LDL/97I, IS/720/99, and IS/Variant2/98) in the ERS with no availabl ...
hemagglutination, etc ; Influenza A virus; antibodies; antibody formation; sialidase; swine; swine influenza; vaccination; veterinary medicine; viruses; Europe; Show all 11 Subjects
Abstract:
... Heterologous prime-boost vaccination with experimental or commercial influenza vaccines has been successful in various animal species. In this study, we have examined the efficacy of alternating 3 different European commercial swine influenza A virus (swIAV) vaccines: the trivalent Respiporc® FLU3 (TIV), the bivalent GRIPORK® (BIV) and the monovalent Respiporc® FLUpan H1N1 (MOV). Five groups of 6 ...
... Toxoplasmosis is an important zoonotic disease worldwide caused by the intracellular parasite Toxoplasma gondii. Cats, being hosts, act as a good sentinel for this disease. Thus, the objective of this study was to determine the seroprevalence of T. gondii in cats by examining serum from seven districts of Metropolitan Lima, Peru. We collected and analyzed 303 cat serum samples, and the owners answ ...
... To explore the immune function of C-type lectin in shrimp, one recombinant C-type lectin (LvLec) was injected into Litopenaeus vannamei. There were four treatments in the experiment: saline group (as control group), recombinant C-type lectin group (LvLec, 1 mg mL⁻¹), Vibrio harveyi group (V. harveyi, 10⁶ cfu mL⁻¹) and recombinant C-type lectin combined with Vibrio harveyi group (LvLec + V. harveyi ...
hemagglutination inhibition test, etc ; Newcastle disease; animal health; chickens; community health; fowl pox; immunity; vaccination; vaccines; Nepal; Tanzania; Show all 11 Subjects
Abstract:
... The co-administration of commercial live fowlpox (FP) and Newcastle disease (ND) vaccines when given by non-invasive (needle-free) routes was demonstrated to be safe and to elicit immunity in two field studies, one in Tanzania the other in Nepal. Both studies were of a cluster-randomised controlled design in which birds were randomly assigned to one of five treatment groups: (i) administration wit ...