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1. Understanding light pollution: Recent advances on its health threats and regulations

Author:
Miao Cao; Ting Xu; Daqiang Yin
Source:
Journal of environmental sciences (China) 2023 v.127 pp. 589-602
ISSN:
1001-0742
Subject:
homeostasis,   etc   ; human health; lighting; melatonin; obesity; pollution; risk assessment; toxicology; China;     Show all 9 Subjects
Abstract:
... The prevalence of artificial lights not only improves the lighting conditions for modern society, but also poses kinds of health threats to human health. Although there are regulations and standards concerning light pollution, few of them are based on the potential contribution of improper lighting to diseases. Therefore, a better understanding of the health threats induced by light pollution may ...
DOI:
10.1016/j.jes.2022.06.020

2. The stimulatory effect and mechanism of low-dose lanthanum on soybean leaf cells

Author:
Yue Ben; Mengzhu Cheng; Yongqiang Liu; Lihong Wang; Qing Yang; Xiaohua Huang; Qing Zhou
Source:
Journal of hazardous materials 2023 v.441 pp. 129924
ISSN:
0304-3894
Subject:
homeostasis,   etc   ; cell growth; endocytosis; gene expression; lanthanum; leaves; plant growth; plasma membrane; soybeans; toxicity;     Show all 10 Subjects
Abstract:
... Light rare earth elements (LREEs) have been long used in agriculture (i.e., mainly via aerially applied LREE fertilizers) based on the fact that low-dose LREEs promote plant growth. Meanwhile, the toxic effects of low-dose LREEs on organisms have also been found. However, the cellular and molecular mechanism of low-dose LREEs acting on organisms remain unclear. Plants are at the beginning of food ...
DOI:
10.1016/j.jhazmat.2022.129924

3. Inhibition of alanine-serine-cysteine transporter 2-mediated auto-enhanced photodynamic cancer therapy of co-nanoassembly between V-9302 and photosensitizer

Author:
Qikun Jiang; Sirun Lu; Xiaolan Xu; Chenxia Bai; Qing Yan; Mengna Fang; Li Huang; Chunming Jin; Yunran Zhang; Jin Sun; Zhonggui He; Chunyang Zhao; Feng Qin; Yongjun Wang; Tianhong Zhang
Source:
Journal of colloid and interface science 2023 v.629 pp. 773-784
ISSN:
0021-9797
Subject:
homeostasis,   etc   ; breast neoplasms; cancer therapy; glutamine; glutathione; hydrophobicity; mice; photochemotherapy; photosensitizing agents; reactive oxygen species;     Show all 10 Subjects
Abstract:
... The efficiency of reactive oxygen species (ROS)-based photodynamic therapy (PDT) is far from satisfactory, because cancer cells can adapt to PDT by upregulating glutathione (GSH) levels. The GSH levels in tumor cells are determined based on glutamine availability via alanine-serine-cysteine transporter 2 (ASCT2)-mediated entry into cells. Herein, we develop co-assembled nanoparticles (PPa/V-9302 N ...
DOI:
10.1016/j.jcis.2022.05.044

4. The transcription factor SlNAP1 increases salt tolerance by modulating ion homeostasis and ROS metabolism in Solanum lycopersicum

Author:
Nanshan Du; Lu Xue; Dongqi Xue; Xiaoxing Dong; Qian Yang; Mohammad Shah Jahan; Hui Guo; Ruike Fu; Yanhui Wang; Fengzhi Piao
Source:
Gene 2023 v.849 pp. 146906
ISSN:
0378-1119
Subject:
homeostasis,   etc   ; Solanum lycopersicum; antioxidant activity; antioxidants; genes; genetically modified organisms; metabolism; oxidoreductases; salt stress; salt tolerance; tomatoes; transcription factors;     Show all 12 Subjects
Abstract:
... NAC transcription factors (TFs) play an important role in the plant resistant response to biotic and abiotic stresses. However, the functions of the most NAC TFs are still unknown, especially in tomato. Here, we identified and functionally characterized an NAC TFs, SlNAP1, in tomato, and found that SlNAP1 was significantly induced by salt stress. Under 150 mM NaCl treatments, morphological indexes ...
DOI:
10.1016/j.gene.2022.146906

5. Based on multi-omics technology study the antibacterial mechanisms of pH-dependent N-GQDs beyond ROS

Author:
Wanfeng Wu; Yanan Qin; Yan Fang; Yukun Zhang; Shuxuan Shao; Fanxing Meng; Minwei Zhang
Source:
Journal of hazardous materials 2023 v.441 pp. 129954
ISSN:
0304-3894
Subject:
homeostasis,   etc   ; antibacterial properties; bacteria; cell death; energy metabolism; graphene; multiomics; nanomaterials; nucleic acids; osmotic pressure; pH; peroxidase; reactive oxygen species;     Show all 13 Subjects
Abstract:
... Currently, graphene quantum dots (GQDs) are widely used as antibacterial agents, and their effects are dependent on the reactive oxygen species (ROS) generated by photodynamic and peroxidase activities. Nevertheless, the supply of substrates or light greatly limits GQDs application. Besides, due to compensatory mechanisms in bacteria, comprehensive analysis of the molecular mechanism underlying th ...
DOI:
10.1016/j.jhazmat.2022.129954

6. Photomorphogenic tomato mutants high-pigment 1 and aurea responses to iron deficiency

Author:
Marina Alves Gavassi; Frederico Rocha Rodrigues Alves; Carolina Cristina Monteiro; Lucas Aparecido Gaion; Letícia Rodrigues Alves; Renato de Mello Prado; Priscila Lupino Gratão; Rogério Falleiros Carvalho
Source:
Scientia horticulturae 2023 v.307 pp. 111502
ISSN:
0304-4238
Subject:
homeostasis,   etc   ; Solanum lycopersicum; anthocyanins; biosynthesis; chlorophyll; chlorosis; genotype; growth retardation; lipid peroxidation; nutrient content; nutrient deficiencies; plant development; plant growth; tomatoes;     Show all 14 Subjects
Abstract:
... Iron (Fe) is a micronutrient for plant development, as constituent of several photosynthesis- and respiration-related proteins and enzymes. Consequently, Fe deficiency leads to chlorosis in leaves and plant growth impairment. It has become increasingly evident that light signals coordinate iron homeostasis in plants. To further address new insights into how light is a fundamental part of Fe defici ...
DOI:
10.1016/j.scienta.2022.111502

7. Prediction of intestinal stem cell regulatory genes from Drosophila gut damage model created using multiple inducers: Differential gene expression-based protein-protein interaction network analysis

Author:
Seung Hun Lee; Dooseon Hwang; Tae-Won Goo; Eun-Young Yun
Source:
Developmental and comparative immunology 2023 v.138 pp. 104539
ISSN:
0145-305X
Subject:
homeostasis,   etc   ; Drosophila melanogaster; gene expression regulation; genes; innate immunity; intestines; models; oral administration; prediction; protein-protein interactions; sequence analysis; stem cells;     Show all 12 Subjects
Abstract:
... Intestinal tissue functions in innate immunity to prevent the entry of harmful substances, and to maintain homeostasis through the constant proliferation of intestinal stem cells (ISC). To understand the mechanisms which regulate ISC in response to gut damage, we identified 81 differentially expressed genes (DEGs) through RNA-seq analysis after oral administration of three intestinal-damaging subs ...
DOI:
10.1016/j.dci.2022.104539

8. Hepatic metabolism-related effects of polysaccharides from red kidney bean and small black soybean on type 2 diabetes

Author:
Zhouya Bai; Xiaojun Huang; Guangjie Wu; Yujia Zhou; Xingchao Deng; Jingrui Yang; Junyi Yin; Shaoping Nie
Source:
Food chemistry 2023 v.403 pp. 134334
ISSN:
0308-8146
Subject:
homeostasis,   etc   ; food chemistry; glucose; kidney beans; lipid metabolism; liver function; metabolites; noninsulin-dependent diabetes mellitus; phosphatidylcholines; phosphatidylethanolamines; polysaccharides; protective effect; soybeans;     Show all 13 Subjects
Abstract:
... In our previous study, two crude polysaccharides from red kidney bean and small black soybean (RK, SB) have shown the alleviative effect on type 2 diabetic mice. Meanwhile, hepatic dysfunction usually accompanied with type 2 diabetes mellitus (T2DM), and closely related to glucose and lipid homeostasis. Therefore, this time we further investigated the protective effect on hepatic dysfunction of RK ...
DOI:
10.1016/j.foodchem.2022.134334

9. Occurrences and potential lipid-disrupting effects of phthalate metabolites in humpback dolphins from the South China Sea

Author:
Zhenhui Xie; Xiyang Zhang; Yanqing Xie; Jiaxue Wu; Yuping Wu
Source:
Journal of hazardous materials 2023 v.441 pp. 129939
ISSN:
0304-3894
Subject:
homeostasis,   etc   ; chronic exposure; dolphins; lipid metabolism; lipids; liver; metabolites; peroxisome proliferator-activated receptor alpha; phthalates; pollution; wildlife; China; South China Sea;     Show all 13 Subjects
Abstract:
... Phthalate esters (PAEs) are ubiquitous environmental contaminants, arising growing public concern. Nevertheless, information on the exposure and risks of PAEs in wildlife remains limited. Here, we conducted the first investigation of the occurrences, spatiotemporal trends, and potential risks of twelve metabolites of PAEs (mPAEs) in 74 humpback dolphins from the northern South China Sea during 200 ...
DOI:
10.1016/j.jhazmat.2022.129939

10. Association between serum levels of TSH and free T4 and per- and polyfluoroalkyl compounds concentrations in pregnant women

Author:
Aijing Li; Jian Hou; Jianjie Fu; Yinan Wang; Yifei Hu; Taifeng Zhuang; Menglong Li; Maoyong Song; Guibin Jiang
Source:
Journal of environmental sciences (China) 2023 v.124 pp. 11-18
ISSN:
1001-0742
Subject:
homeostasis,   etc   ; antibodies; blood serum; early development; fetal development; iodide peroxidase; pregnancy; regression analysis; thyroid function; thyroid hormones; thyrotropin; thyroxine; weight gain; China;     Show all 14 Subjects
Abstract:
... Many per- and polyfluoralkyl substances (PFASs) may disrupt maternal thyroid hormone homeostasis in pregnancy. Concerns should be raised regarding the PFASs exposure in pregnant women because thyroid hormones are involved in the early development of the fetus. In this study, we measured the concentrations of 13 PFASs, including five novel short-chain PFASs, in serum from 123 pregnant women in Beij ...
DOI:
10.1016/j.jes.2021.10.026

11. Novel association of SNP rs2297828 in PRDM16 gene with predisposition to type 2 diabetes

Author:
Hongmei Zhang; Qiuyue Guan; Ruyi Wang; Shanshan Yang; Xiaoqian Yu; Daxin Cui; Zhiguang Su
Source:
Gene 2023 v.849 pp. 146916
ISSN:
0378-1119
Subject:
homeostasis,   etc   ; alleles; blood; energy; genetic variation; glucose; heterozygosity; homozygosity; lipid metabolism; luciferase; models; noninsulin-dependent diabetes mellitus; promoter regions; reporter genes; risk; transcription factors;     Show all 16 Subjects
Abstract:
... Transcriptional regulator PRD1-BF-1-RIZ1 homology (PR) domain containing protein-16 (PRDM16) has a fundamental function in maintaining energy homeostasis and regulating glucose and lipid metabolism, which are responsible for the development of type 2 diabetes (T2D). However, the impact of genetic variation of PRDM16 gene on T2D risk remains to be investigated. Thus, we evaluated the possible assoc ...
DOI:
10.1016/j.gene.2022.146916

12. Influence of biosynthesized nanoparticles exposure on mortality, residual deposition, and intestinal bacterial dysbiosis in Cyprinus carpio

Author:
Mian Adnan Kakakhel; Nadia Bibi; Heba H. Mahboub; Fasi Wu; Wasim Sajjad; Syed Zaheer Ud Din; Ahmed A. Hefny; Wanfu Wang
Source:
Comparative biochemistry and physiology 2023 v.263 pp. 109473
ISSN:
1532-0456
Subject:
homeostasis,   etc   ; Bacteroidetes; Cyprinus carpio; Planctomycetes; Tenericutes; animal growth; bacterial communities; bioaccumulation; biosynthesis; blood; dysbiosis; freshwater fish; intestines; liver; mortality; multidimensional scaling; nanoparticles; nanosilver; toxicity;     Show all 19 Subjects
Abstract:
... Nanotechnology has revealed profound possibilities for the applications in applied sciences. The nanotechnology works based on nanoparticles. Among nanoparticles, silver nanoparticles largely introduced into aquatic environments during fabrication. Which cause severe contamination in the environment specially in freshwater fish. Therefore, the current study was a pioneer attempt to use the animal ...
DOI:
10.1016/j.cbpc.2022.109473

13. Joint effect of multiple air pollutants on cardiometabolic health in normal-weight and obese adults: A novel insight into the role of circulating free fatty acids

Author:
Wenlou Zhang; Wanzhou Wang; Luyi Li; Mark R. Miller; Liyan Cui; Junxiu Liu; Yang Wang; Dayu Hu; Shan Liu; Junhui Xu; Shaowei Wu; Junchao Duan; Zhiwei Sun; Xinbiao Guo; Furong Deng
Source:
Science of the total environment 2023 v.856 pp. 159014
ISSN:
0048-9697
Subject:
homeostasis,   etc   ; Bayesian theory; air; air pollutants; air pollution; biomarkers; blood lipids; blood pressure; coagulation; environment; enzymes; high density lipoprotein cholesterol; inflammation; lipogenesis; metabolomics; triacylglycerols;     Show all 16 Subjects
Abstract:
... The cardiometabolic effects of air pollution in the context of mixtures and the underlying mechanisms remain not fully understood. This study aims to investigate the joint effect of air pollutant mixtures on a broad range of cardiometabolic parameters, examine the susceptibility of obese individuals, and determine the role of circulating fatty acids. In this panel study, metabolically healthy norm ...
DOI:
10.1016/j.scitotenv.2022.159014

14. Integrated physiologic and proteomic analysis of Stropharia rugosoannulata mycelia in response to Cd stress

Author:
Qin Dong; Mingjie Chen; Yaru Zhang; Panpan Song; Huanling Yang; Yan Zhao; Changxia Yu; Lei Zha
Source:
Journal of hazardous materials 2023 v.441 pp. 129877
ISSN:
0304-3894
Subject:
homeostasis,   etc   ; Stropharia rugosoannulata; antioxidants; bioremediation; biosynthesis; energy; energy metabolism; gene expression regulation; growth retardation; human health; isoleucine; leucine; mycelium; pollution; proteome; proteomics; soil; toxicity; valine;     Show all 19 Subjects
Abstract:
... Soil Cd pollution seriously threatens environment and human health. Due to its ability to absorb and accumulate Cd in mycelia, Stropharia rugosoannulata could be a potential candidate for bioremediation of Cd-contaminated soils; however, the response mechanism of mycelia to Cd stress is still unclear. In this study, the physiologic and proteomic differences of S. rugosoannulata mycelia under 0.2 m ...
DOI:
10.1016/j.jhazmat.2022.129877

15. Prenatal exposure to organophosphate esters is associated with decreased anogenital distance in offspring

Author:
Min Luan; Hong Liang; Yafei Chen; Da Chen; Honglei Ji; Hexia Chen; Maohua Miao; Wei Yuan
Source:
Science of the total environment 2023 v.856 pp. 159050
ISSN:
0048-9697
Subject:
homeostasis,   etc   ; Bayesian theory; biomarkers; biphenyl; cohort studies; environment; gestational age; humans; maternal exposure; metabolites; organophosphorus compounds; phosphates; progeny; reproductive toxicology; rodents; sex hormones; steroid hormones; urine;     Show all 18 Subjects
Abstract:
... Evidence from in vitro and rodent studies suggests that organophosphate esters (OPEs) may disrupt sex steroid hormone homeostasis, but no human studies, to date, have examined the effects of in utero exposure to OPEs on offspring reproductive development. Anogenital distance (AGD) is a sensitive biomarker of fetal hormonal milieu and has been used to assess reproductive toxicity. We evaluated the ...
DOI:
10.1016/j.scitotenv.2022.159050

16. Pepper autophagy related gene CaATG8e differentially regulates plant tolerance to heat and salt stress

Author:
Minmin Liang; Haiyan Li; Kang Yong; Guohong Huang; Yuling Guo; Minghui Lu
Source:
Scientia horticulturae 2023 v.308 pp. 111559
ISSN:
0304-4238
Subject:
homeostasis,   etc   ; Arabidopsis; Solanaceae; autophagosomes; autophagy; chlorophyll; computer software; electrolyte leakage; genes; heat; heat shock response; heat stress; heat tolerance; pepper; phylogeny; protein degradation; salt stress; salt tolerance; viruses;     Show all 19 Subjects
Abstract:
... As a conserved protein degradation system, autophagy plays important roles in removing or degrading misfolded and denatured proteins to maintain the homeostasis in cells. As a core member of autophagy, the involvement of ATG8 in plant tolerance to abiotic stress is paid more attention. In this study, by the SMART online tool, the Atg8 conserved domain was detected in CaATG8e, and by the MEGA11 sof ...
DOI:
10.1016/j.scienta.2022.111559

17. Exogenous bile acids regulate energy metabolism and improve the health condition of farmed fish

Author:
Lei Wang; Gladstone Sagada; Chenyang Wang; Ruichen Liu; Qiang Li; Chen Zhang; Yunzhi Yan
Source:
Aquaculture 2023 v.562 pp. 738852
ISSN:
0044-8486
Subject:
homeostasis,   etc   ; absorption; antioxidants; aquaculture; bile; biosynthesis; energy; energy metabolism; farmed fish; feed industry; fish health; glucose; growth performance; growth promotion; high carbohydrate diet; intestinal microorganisms; lipids; liver; meat quality;     Show all 19 Subjects
Abstract:
... The rapid expansion of aquaculture has led to increased demand for protein sources for feed production. Lipids and carbohydrates can serve as energy sources and induce a “protein-sparing” effect. However, excessive dietary lipids and carbohydrates may cause lipid accumulation in the liver, impair immune and antioxidant capacities, thus hidering the growth and meat quality of farmed fish. Bile acid ...
DOI:
10.1016/j.aquaculture.2022.738852

18. Sex difference in effects of intermittent heat exposure on hepatic lipid and glucose metabolisms

Author:
Guoqing Zhang; Yindan Wang; Ran Li; Jing Peng; Jinna Zhang; Renjie Hu; Lu Zhang; Yunlu Wu; Qinghua Sun; Cuiqing Liu
Source:
Science of the total environment 2023 v.854 pp. 158704
ISSN:
0048-9697
Subject:
homeostasis,   etc   ; beta oxidation; body weight; climate; environment; exports; fatty acids; females; free fatty acids; glucose; glucose tolerance; glycolysis; heat; heat-shock protein 70; insulin resistance; lipolysis; liver; males; mitochondria; triacylglycerols;     Show all 20 Subjects
Abstract:
... Global climate warming has drawn worldwide attention. However, the health impact of heat exposure is still controversial. This study aimed to explore the exact effects and sex differential vulnerability under intermittent heat exposure (IHE) patterns and tried to elucidate the potential mechanisms by which IHE modulated hepatic lipid and glucose homeostasis. Both female and male C57BL/6 N mice wer ...
DOI:
10.1016/j.scitotenv.2022.158704

19. Stereoselective metabolic disruption of cypermethrin by remolding gut homeostasis in rat

Author:
Quan Zhang; Sijia Gu; Yan Wang; Shitao Hu; Siqing Yue; Cui Wang
Source:
Journal of environmental sciences (China) 2023 v.126 pp. 761-771
ISSN:
1001-0742
Subject:
homeostasis,   etc   ; Elusimicrobia; Firmicutes; Verrucomicrobia; blood glucose; body weight; cypermethrin; digestive system; energy; glycogen; glycolipids; hyperlipidemia; inflammation; insulin resistance; intestinal microorganisms; phenotype; probiotics; pyrethrins; rats; species diversity; stereoselectivity; triacylglycerols; weight loss; China;     Show all 24 Subjects
Abstract:
... Cypermethrin (CYP), a prototypical synthetic pyrethroid, reportedly causes metabolic disruption, while its stereoselective impact remains elusive. This study initially revealed that only α-CYP caused significant weight loss at 8.5 mg/(kg•day) in rats. All three CYP isomers caused the accumulation of hepatic glycogen, and hyperlipemia phenotype as the increment of total triglyceride. Rats treated w ...
DOI:
10.1016/j.jes.2022.03.035

20. DBDPE and ZnO NPs synergistically induce neurotoxicity of SK-N-SH cells and activate mitochondrial apoptosis signaling pathway and Nrf2-mediated antioxidant pathway

Author:
Liying Dong; Shutao Wang; Lin Zhang; Dongmei Liu; Hong You
Source:
Journal of hazardous materials 2023 v.441 pp. 129872
ISSN:
0304-3894
Subject:
homeostasis,   etc   ; antioxidant enzymes; apoptosis; bioinformatics; caspase-3; cytochrome c; cytotoxicity; decabromodiphenyl ethane; flame retardants; gene expression; humans; membrane potential; mitochondria; mitochondrial membrane; nanoparticles; neurotoxicity; oxidative stress; protein synthesis; risk perception; viability; zinc oxide;     Show all 21 Subjects
Abstract:
... Decabromodiphenyl ethane (DBDPE), a new brominated flame retardant, could negatively affect neurobehavior and pose health risks to humans. Humans are also exposed to widely used nanomaterials. This study investigated the combined toxic effects and action types of DBDPE and Zinc oxide nanoparticles (ZnO NPs) on human neuroblastoma SK-N-SH cells and the toxicity mechanisms. DBDPE inhibited the viabi ...
DOI:
10.1016/j.jhazmat.2022.129872