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1. Teaching Shrimps Self-Defense to Fight Infections

Author:
Norouzitallab, Parisa; Baruah, Kartik; Vanrompay, Daisy; Bossier, Peter
Source:
Trends in biotechnology 2019 v.37 no.1 pp. 16-19
ISSN:
0167-7799
Subject:
immunity,   etc   ; disease control; shrimp;     Show all 3 Subjects
Abstract:
... A paradigm shift in our understanding of shrimp immunity offers the potential to develop novel disease-control strategies. We summarize cutting-edge findings on the phenomenon of trained immunity in shrimps and discuss how it may contribute to new avenues for controlling disease in these aquaculturally important animals. ...
DOI:
10.1016/j.tibtech.2018.05.007

2. Peptidoglycan recognition proteins in insect immunity

Author:
Wang, Qiang; Ren, Meijia; Liu, Xiaoyong; Xia, Hengchuan; Chen, Keping
Source:
Molecular immunology 2019 v.106 pp. 69-76
ISSN:
0161-5890
Subject:
adaptive immunity; innate immunity; insect immunity,   etc   ; insects; pathogen-associated molecular patterns; peptidoglycans; proteins;     Show all 7 Subjects
Abstract:
... Insects lack an acquired immune system and rely solely on the innate immune system to combat microbial infection. The innate immunity of insects mainly depends on the interaction between the host's pattern recognition receptor (PRR) and pathogen-associated molecular pattern (PAMP). The peptidoglycan recognition proteins (PGRPs) family is the most important pattern recognition receptor (PRR) for in ...
DOI:
10.1016/j.molimm.2018.12.021

3. Tuning the Orchestra: miRNAs in Plant Immunity

Author:
Wang, Wenyi; Galili, Gad
Source:
Trends in plant science 2019 v.24 no.3 pp. 189-191
ISSN:
1360-1385
Subject:
innate immunity,   etc   ; genes; messenger RNA; microRNA;     Show all 4 Subjects
Abstract:
... miRNAs act as negative modulators of target genes and play key roles in post-transcriptional gene regulation through sequence-specific mRNA cleavage and translational inhibition. Two recent reports highlight the orchestrated role of miRNA2111 and miRNA172b in plant innate immunity [1,2] (Science 2018;362:233–236; Plant Cell 2018;30:2779–2794). ...
DOI:
10.1016/j.tplants.2019.01.009

4. A novel deep learning method for the classification of power quality disturbances using deep convolutional neural network

Author:
Wang, Shouxiang; Chen, Haiwen
Source:
Applied energy 2019 v.235 pp. 1126-1140
ISSN:
0306-2619
Subject:
immunity,   etc   ; electrical equipment; energy; neural networks; risk;     Show all 5 Subjects
Abstract:
... With the integration of multiple energy systems, there are more and more deterioration risks of power quality in different energy production, transformation, delivery and consumption stages. Automatic classification of power quality disturbances is the foundation to deal with power quality problem. From the traditional point of view, the identification process of power quality disturbances should ...
DOI:
10.1016/j.apenergy.2018.09.160

5. Pointwise SAR image change detection based on stereograph model with multiple-span neighbourhood information

Author:
Wang, Jun; Yang, Xuezhi; Jia, Lu
Source:
International journal of remote sensing 2019 v.40 no.1 pp. 31-50
ISSN:
1366-5901
Subject:
immunity,   etc   ; models; remote sensing; synthetic aperture radar;     Show all 4 Subjects
Abstract:
... In this article, a novel pointwise approach is proposed for change detection in bi-temporal synthetic aperture radar (SAR) images using stereograph model. Due to the fact that SAR image suffers from the speckle noise, a pointwise approach based on a set of characteristic points only, not on the whole pixels, seems to be more efficient. Moreover, the correlations of neighbourhood points which have ...
DOI:
10.1080/01431161.2018.1488284

6. Legume Nodules: Massive Infection in the Absence of Defense Induction

Author:
Berrabah, Fathi; Ratet, Pascal; Gourion, Benjamin
Source:
Molecular plant-microbe interactions 2019 v.32 no.1 pp. 35-44
ISSN:
0894-0282
Subject:
immunity,   etc   ; bacteria; legumes; nitrogen; symbiosis; tissues;     Show all 6 Subjects
Abstract:
... Plants of the legume family host massive intracellular bacterial populations in the tissues of specialized organs, the nodules. In these organs, the bacteria, named rhizobia, can fix atmospheric nitrogen and transfer it to the plant. This special metabolic skill provides to the legumes an advantage when they grow on nitrogen-scarce substrates. While packed with rhizobia, the nodule cells remain al ...
DOI:
10.1094/MPMI-07-18-0205-FI

7. Immune Signaling Pathway during Terminal Bacteroid Differentiation in Nodules

Author:
Yu, Haixiang; Bao, Hanbin; Zhang, Zhongming; Cao, Yangrong
Source:
Trends in plant science 2019
ISSN:
1360-1385
Subject:
innate immunity,   etc   ; Medicago truncatula; signal transduction;     Show all 3 Subjects
Abstract:
... Plant innate immunity plays an important role in regulating symbiotic associations with rhizobia, including during rhizobial infection, rhizobial colonization, and bacteroid differentiation in leguminous plants. Here we propose that an immune signaling pathway similar to plant pattern-triggered immunity (PTI) is required for the regulation of bacteroid differentiation in Medicago truncatula nodule ...
DOI:
10.1016/j.tplants.2019.01.010

8. SAMHD1 Suppression of Antiviral Immune Responses

Author:
Chen, Shuliang; Bonifati, Serena; Qin, Zhihua; St. Gelais, Corine; Wu, Li
Source:
Trends in microbiology 2019 v.27 no.3 pp. 254-267
ISSN:
0966-842X
Subject:
adaptive immunity; innate immunity,   etc   ; DNA; DNA replication; antibody formation; enzymes; inflammation; proteins; viruses;     Show all 9 Subjects
Abstract:
... SAMHD1 is a host triphosphohydrolase that degrades intracellular deoxynucleoside triphosphates (dNTPs) to a lower level that restricts viral DNA synthesis, and thus prevents replication of diverse viruses in nondividing cells. Recent progress indicates that SAMHD1 negatively regulates antiviral innate immune responses and inflammation through interacting with various key proteins in immune signali ...
DOI:
10.1016/j.tim.2018.09.009

9. Memory in Fungal Pathogens Promotes Immune Evasion, Colonisation, and Infection

Author:
Brown, Alistair J.P.; Gow, Neil A.R.; Warris, Adilia; Brown, Gordon D.
Source:
Trends in microbiology 2019 v.27 no.3 pp. 219-230
ISSN:
0966-842X
Subject:
immunity,   etc   ; dogs; fungi; humans; immune evasion; lifestyle; memory; pathogens; prediction;     Show all 9 Subjects
Abstract:
... By analogy with Pavlov’s dogs, certain pathogens have evolved anticipatory behaviours that exploit specific signals in the human host to prepare themselves against imminent host challenges. This adaptive prediction, a type of history-dependent microbial behaviour, represents a primitive form of microbial memory. For fungal pathogens, adaptive prediction helps them circumvent nutritional immunity, ...
DOI:
10.1016/j.tim.2018.11.001

10. Transmissible vaccines whose dissemination rates vary through time, with applications to wildlife

Author:
Smithson, Mark W.; Basinki, Andrew J.; Nuismer, Scott L.; Bull, James J.
Source:
Vaccine 2019 v.37 no.9 pp. 1153-1159
ISSN:
0264-410X
Subject:
herd immunity,   etc   ; engineering; hosts; humans; pathogens; viral vaccines; wildlife;     Show all 7 Subjects
Abstract:
... Transmission is a potential property of live viral vaccines that remains largely unexploited but may lie within the realm of many engineering designs. While likely unacceptable for vaccines of humans, transmission may be highly desirable for vaccines of wildlife, both to protect natural populations and also to limit zoonotic transmissions into humans. Defying intuition, transmission alone does not ...
DOI:
10.1016/j.vaccine.2019.01.018

11. Production of functional human interleukin 37 using plants

Author:
Alqazlan, Nadiyah; Diao, Hong; Jevnikar, Anthony M.; Ma, Shengwu
Source:
Plant cell reports 2019 v.38 no.3 pp. 391-401
ISSN:
0721-7714
Subject:
adaptive immunity; innate immunity,   etc   ; agglutinins; bioactive properties; bioreactors; humans; in vitro studies; inflammation; interleukins; promoter regions; soybeans; tobacco; transgenic plants;     Show all 13 Subjects
Abstract:
... KEY MESSAGE: We demonstrate for the first time that a fully bioactive human IL-37, a newly discovered cytokine acting as a fundamental inhibitor of innate immunity, can be recombinantly produced in plant cells. Interleukin 37 (IL-37), a newly discovered member of the interleukin (IL)-1 family of cytokines, plays a pivotal role in limiting innate inflammation and suppressing acquired immune respons ...
DOI:
10.1007/s00299-019-02377-2

12. Widespread positive selection on cetacean TLR extracellular domain

Author:
Xu, Shixia; Tian, Ran; Lin, Yurui; Yu, Zhenpeng; Zhang, Zepeng; Niu, Xu; Wang, Xiaohong; Yang, Guang
Source:
Molecular immunology 2019 v.106 pp. 135-142
ISSN:
0161-5890
Subject:
adaptive immunity; innate immunity,   etc   ; Cetacea; Primates; amino acids; aquatic environment; bacteria; birds; codons; habitats; pathogens; receptors; viruses;     Show all 13 Subjects
Abstract:
... Toll like receptors (TLRs), key members of innate immune system, can recognize a wide diversity of pathogens and initiate both innate and adaptive immune responses in vertebrate. Cetaceans must have faced new challenges of pathogens when their terrestrial relatives transitioned from the terrestrial to aquatic environment. Here, we sequenced the extracellular domain (ECD) of 10 TLRs in cetacean lin ...
DOI:
10.1016/j.molimm.2018.12.022

13. The enigmatic neutrophil: what we do not know

Author:
Kubes, Paul
Source:
Cell and tissue research 2018 v.371 no.3 pp. 399-406
ISSN:
0302-766X
Subject:
adaptive immunity; innate immunity,   etc   ; death; neoplasms; neutrophils; pathogens; tissues;     Show all 7 Subjects
Abstract:
... The neutrophil appears to be undergoing a renaissance of sorts. While it was for many years thought to be a killing machine brought into tissues to eradicate pathogens, it is now being implicated in many other processes, ranging from acute injury and repair, chronic inflammatory processes, cancer and auto-immunity. Not only is it an effector of the innate immune response, it appears to also potent ...
DOI:
10.1007/s00441-018-2790-5

14. Performance and altitude: Ways that nutrition can help

Author:
Caris, Aline V; Santos, Ronaldo Vagner Thomatieli
Source:
Nutrition 2019 v.60 pp. 35-40
ISSN:
0899-9007
Subject:
humoral immunity; mucosal immunity,   etc   ; altitude; athletes; carbohydrates; exercise; glutamine; homeostasis; human physiology; humans; hypoxia; immune response; immune system; immunosuppression; inflammation; nutrition; sports;     Show all 17 Subjects
Abstract:
... High altitudes are a challenge for human physiology and for sports enthusiasts. Several reasons lead to deterioration in performance at high altitudes. Hypoxia owing to high altitude causes a breakdown of homeostasis with imbalance in several physiological systems, including the immune system. The reduction in mucosal immunity and inflammation and the predominance of the humoral immune response ca ...
DOI:
10.1016/j.nut.2018.09.030

15. The route of Besnoitia besnoiti tachyzoites inoculation does not influence the clinical outcome of the infection in calves

Author:
Diezma-Díaz, C.; Ferre, I.; Re, M.; Jiménez-Meléndez, A.; Tabanera, E.; González-Huecas, M.; Pizarro-Díaz, M.; Yanguas-Pérez, D.; Brum, P.L.; Blanco-Murcia, J.; Ortega-Mora, L.M.; Álvarez-García, G.
Source:
Veterinary parasitology 2019 v.267 pp. 21-25
ISSN:
0304-4017
Subject:
humoral immunity; innate immunity,   etc   ; Besnoitia besnoiti; blood; calves; cattle diseases; fever; immune response; intravenous injection; lymphatic diseases; males; models; monitoring; signs and symptoms (animals and humans); tachyzoites; tissues;     Show all 16 Subjects
Abstract:
... In a previous attempt, an experimental model of bovine besnoitiosis was established in calves that were intravenously inoculated with different doses of Besnoitia besnoiti tachyzoites. Despite the fact that all infected calves developed the acute stage of disease, only microscopic findings characteristic of chronic besnoitiosis were reported. In the present study, calves were inoculated by subcuta ...
DOI:
10.1016/j.vetpar.2019.02.001

16. Vaccination with human papillomavirus-18 E1 protein plus α-galactosyl-ceramide induces CD8+ cytotoxic response and impairs the growth of E1-expressing tumors

Author:
Amador-Molina, Alfredo; Trejo-Moreno, Cesar; Romero-Rodríguez, Damaris; Sada-Ovalle, Isabel; Pérez-Cárdenas, Enrique; Lamoyi, Edmundo; Moreno, José; Lizano, Marcela
Source:
Vaccine 2019 v.37 no.9 pp. 1219-1228
ISSN:
0264-410X
Subject:
cell-mediated immunity; cross immunity,   etc   ; CD8-positive T-lymphocytes; Papillomaviridae; adjuvants; animal models; cytotoxicity; enzymes; growth retardation; immune response; melanoma; mice; proteins; protocols; vaccination; vaccines; virus replication; women;     Show all 18 Subjects
Abstract:
... CD8+ T cell-mediated immune response plays a major role in the clearance of virus-infected cells, including human papillomavirus (HPV). The effective treatment of women with normal cytology but persistent high risk-HPV infection or with low-grade intraepithelial lesions could take advantage of novel strategies based on vaccination with viral immunological targets with a wide spectrum of cross-prot ...
DOI:
10.1016/j.vaccine.2018.12.036

17. DNA vaccination for finfish aquaculture

Author:
Collins, Catherine; Lorenzen, Niels; Collet, Bertrand
Source:
Fish & shellfish immunology 2019 v.85 pp. 106-125
ISSN:
1050-4648
Subject:
adaptive immunity; innate immunity,   etc   ; DNA; Rhabdoviridae; commercialization; consumer acceptance; farmed fish; fish culture; genetically modified organisms; mechanism of action; pathogens; recombinant vaccines; shellfish; vaccination; Canada; Europe;     Show all 16 Subjects
Abstract:
... In fish, DNA vaccines have been shown to give very high protection in experimental facilities against a number of viral diseases, particularly diseases caused by rhabdoviruses. However, their efficacy in generating protection against other families of fish viral pathogens is less clear. One DNA vaccine is currently in use commercially in fish farms in Canada and the commercialisation of another wa ...
DOI:
10.1016/j.fsi.2018.07.012

18. Recombinant flagellins with deletions in domains D1, D2, and D3: Characterization as novel immunoadjuvants

Author:
Biedma, Marina E.; Cayet, Delphine; Tabareau, Julien; Rossi, Andrés H.; Ivičak-Kocjan, Karolina; Moreno, Griselda; Errea, Agustina; Soulard, Daphnée; Parisi, Gustavo; Jerala, Roman; Berguer, Paula; Rumbo, Martin; Sirard, Jean Claude
Source:
Vaccine 2019 v.37 no.4 pp. 652-663
ISSN:
0264-410X
Subject:
adaptive immunity; innate immunity,   etc   ; Salmonella enterica; Toll-like receptor 5; adjuvants; antibodies; antigens; denaturation; epithelium; flagellin; heat; immunostimulants; intranasal administration; mice; ovalbumin; vaccination; vaccines;     Show all 17 Subjects
Abstract:
... Bacterial flagellin activates the innate immune system and ultimately the adaptive immune system through a Toll-like receptor 5 (TLR5)-dependent signaling mechanism. Given that TLR5 is widely distributed in epithelia, flagellin is currently being developed as a mucosal adjuvant. Flagellin FliC from Salmonella enterica has four domains: the conserved D0 and D1 domains and the hypervariable D2 and D ...
DOI:
10.1016/j.vaccine.2018.12.009

19. Effect of sex and reproductive status on the immunity of the temperate bat Myotis daubentonii

Author:
Ruoss, Sara; Becker, Nina I.; Otto, Matthias S.; Czirják, Gábor Á.; Encarnação, Jorge A.
Source:
Mammalian biology = 2019 v.94 pp. 120-126
ISSN:
1616-5047
Subject:
cell-mediated immunity; innate immunity,   etc   ; Myotis; climate; energy; females; health status; hemagglutination; hemolysis; immunoglobulin G; lactation; leukocyte count; males; mammals; pathogens; public health; reproduction;     Show all 17 Subjects
Abstract:
... Studies of immunity in bat species are rare. However, it is important to determine immunological variations to identify factors influencing the health status of these endangered mammals from an evolutionary, ecological, conservation, and public health point of view. Immunity is highly variable and can be influenced by both internal (e.g. hormone levels, energy demand) and external factors (e.g. pa ...
DOI:
10.1016/j.mambio.2018.05.010

20. Efficacy of Montanide™ ISA 763 A VG as aquatic adjuvant administrated with an inactivated Vibrio harveyi vaccine in turbot (Scophthalmus maximus L.)

Author:
Xu, Wenting; Jiao, Chenglong; Bao, Pengcheng; Liu, Qin; Wang, Pengbo; Zhang, Ruilin; Liu, Xiaohong; Zhang, Yuanxing
Source:
Fish & shellfish immunology 2019 v.84 pp. 56-61
ISSN:
1050-4648
Subject:
humoral immunity; innate immunity,   etc   ; Scophthalmus maximus; Vibrio harveyi; adjuvants; antibacterial properties; antibodies; aquaculture industry; financial economics; fish diseases; inactivated vaccines; lysozyme; pathogens; shellfish; turbot; vaccination; China;     Show all 17 Subjects
Abstract:
... Turbot (Scophthalmus maximus L.) is a commercially important fish species in China. Despite of its great economic potential, fish farms often suffer severe economic losses due to certain fish diseases. Vaccination has become a common strategy to prevent diseases caused by pathogens in aquaculture industry. However, no inactivated vaccine against Vibrio harveyi of turbot has been reported so far. I ...
DOI:
10.1016/j.fsi.2018.09.024