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1. Effectiveness of 10 and 13-valent pneumococcal conjugate vaccines against invasive pneumococcal disease in European children: SpIDnet observational multicentre study

Author:
Camelia Savulescu; Pavla Krizova; Palle Valentiner-Branth; Shamez Ladhani; Hanna Rinta-Kokko; Corinne Levy; Jolita Mereckiene; Mirjam Knol; Brita A. Winje; Pilar Ciruela; Sara de Miguel; Marcela Guevara; Laura MacDonald; Jana Kozakova; Hans-Christian Slotved; Norman K. Fry; J. Pekka Nuorti; Kostas Danis; Mary Corcoran; Arie van der Ende; Didrik F. Vestrheim; Carmen Munoz-Almagro; Juan-Carlos Sanz; Jesus Castilla; Andrew Smith; Edoardo Colzani; Lucia Pastore Celentano; Germaine Hanquet; SpIDnet VE study group
Source:
Vaccine 2022 pp. -
ISSN:
0264-410X
Subject:
secondary immunization,   etc   ; Streptococcus pneumoniae; odds ratio; serotypes; vaccination; vaccines;     Show all 6 Subjects
Abstract:
... Pneumococcal conjugate vaccines covering 10 (PCV10) and 13 (PCV13) serotypes have been introduced in the infant immunization schedule of most European countries in 2010-11. To provide additional real-life data, we measured the effectiveness of PCV10 and PCV13 against invasive pneumococcal disease (IPD)in children of 12 European sites (SpIDnet). We compared the vaccination status of PCV10 and PCV13 ...
DOI:
10.1016/j.vaccine.2022.05.011

2. Fourteen years of the Pregnancy Registry on maternal immunisation with a reduced-antigen-content tetanus-diphtheria-acellular pertussis (Tdap) vaccine

Author:
Anastasia Kuznetsova; Maria Angeles Ceregido; Anne Jourquin; Laura Campora; Fernanda Tavares-Da-Silva
Source:
Vaccine 2022 v.40 no.6 pp. 904-911
ISSN:
0264-410X
Subject:
immunization,   etc   ; abortion (animals); conception; databases; fetal death; monitoring; vaccines;     Show all 7 Subjects
Abstract:
... GSK initiated a Pregnancy Registry in the United States (US) for the reduced-antigen-content tetanus-diphtheria-acellular pertussis (Tdap; Boostrix, GSK) vaccine with the aim to detect and describe pregnancy outcomes in women vaccinated with Boostrix 28 days before estimated conception or during pregnancy. Voluntary reports of pregnancy exposure to Boostrix received from spontaneous and post-marke ...
DOI:
10.1016/j.vaccine.2021.12.050

3. Determinants of immunization status of children under two years old in Sumatera, Indonesia: A multilevel analysis of the 2020 Indonesia National Socio-Economic Survey

Author:
Muhammad Sulkhan Setiawan; Arie Wahyu Wijayanto
Source:
Vaccine 2022 v.40 no.12 pp. 1821-1828
ISSN:
0264-410X
Subject:
immunization,   etc   ; children; education; employment; regression analysis; socioeconomics; surveys; vaccines; Indonesia;     Show all 9 Subjects
Abstract:
... The success of a basic immunization program among children has been known as the cheapest and most effective approach in improving child survival against preventable diseases. This study aims to examine the determinant factors at the individual and contextual level that affect the provision of complete basic immunization for children aged 12–23 months in Sumatra, Indonesia. Using the 2020 Indonesi ...
DOI:
10.1016/j.vaccine.2022.02.010

4. WHO preferred product characteristics for monoclonal antibodies for passive immunization against respiratory syncytial virus (RSV) disease in infants – Key considerations for global use

Author:
Erin Sparrow; Ifedayo Adetifa; Nathorn Chaiyakunapruk; Thomas Cherian; Deshayne B. Fell; Barney S. Graham; Bruce Innis; David C. Kaslow; Ruth A. Karron; Harish Nair; Kathleen M. Neuzil; Samir Saha; Peter G. Smith; Padmini Srikantiah; Fred Were; Heather J. Zar; Daniel Feikin
Source:
Vaccine 2022 pp. -
ISSN:
0264-410X
Subject:
immunization,   etc   ; Respiratory syncytial virus; World Health Organization; public health; vaccines;     Show all 5 Subjects
Abstract:
... World Health Organization (WHO) preferred product characteristics describe preferences for product attributes that would help optimize value and use to address global public health needs, with a particular focus on low- and middle-income countries. Having previously published preferred product characteristics for both maternal and paediatric respiratory syncytial virus (RSV) vaccines, WHO recently ...
DOI:
10.1016/j.vaccine.2022.02.040

5. Analysis of population immunity to poliovirus following cessation of trivalent oral polio vaccine

Author:
Arend Voorman; Hil Lyons; Caroline Bennette; Stephanie Kovacs; Jeevan K. Makam; John F Vertefeuille; Graham Tallis
Source:
Vaccine 2022 pp. -
ISSN:
0264-410X
Subject:
immunization,   etc   ; Enterovirus C; dynamic models; immunogenicity; mucosal immunity; risk; serotypes; vaccines;     Show all 8 Subjects
Abstract:
... The global withdrawal of trivalent oral poliovirus vaccine (OPV) (tOPV, containing Sabin poliovirus strains serotypes 1, 2 and 3) from routine immunization, and the introduction of bivalent OPV (bOPV, containing Sabin poliovirus strains serotypes 1 and 3) and trivalent inactivated poliovirus vaccine (IPV) into routine immunization was expected to improve population serologic and mucosal immunity t ...
DOI:
10.1016/j.vaccine.2022.03.013

6. A flow-through chromatography purification process for Vero cell-derived influenza virus (H7N9)

Author:
ChengRui Fei; JingXia Gao; ChengHua Fei; Lei Ma; WenYong Zhu; LingYu He; YaNan Wu; ShaoHui Song; WeiDong Li; Jian Zhou; GuoYang Liao
Source:
Journal of virological methods 2022 v.301 pp. 114408
ISSN:
0166-0934
Subject:
immunization,   etc   ; DNA; Orthomyxoviridae; albumins; anion exchange chromatography; hemagglutinins; influenza; purification methods; viruses;     Show all 9 Subjects
Abstract:
... Immunization is the most effective way to respond to an influenza epidemic. To produce Vero cell-derived influenza vaccines, a more efficient, stable and economical purification process is required. In this study, we purified the H7N9 influenza virus grown in Vero cells that were cultured in a serum-free medium by using a combination of anion exchange chromatography (AEC) and ligand-activated core ...
DOI:
10.1016/j.jviromet.2021.114408

7. A population-based analysis to determine the impact of the 13-valent pneumococcal conjugate vaccine on community-acquired pneumonia in British Columbia, Canada

Author:
Nirma K Vadlamudi; David M Patrick; Caren Rose; Mohsen Sadatsafavi; Linda Hoang; Fawziah Marra
Source:
Vaccine 2022 v.40 no.7 pp. 1047-1053
ISSN:
0264-410X
Subject:
immunization,   etc   ; Streptococcus pneumoniae; etiology; morbidity; mortality; pneumonia; regression analysis; vaccines; British Columbia;     Show all 9 Subjects
Abstract:
... Pneumonia is a leading cause of morbidity and mortality globally. We determined the impact of 13-valent pneumococcal conjugate vaccine (PCV13) use on community-acquired pneumonia (CAP) rates eight years after the vaccine was introduced in the infant immunization program. Using diagnostic codes from administrative databases, we calculated the overall and age-specific CAP incidence per month (2000–2 ...
DOI:
10.1016/j.vaccine.2021.12.065

8. Concurrent outbreaks of circulating vaccine-derived poliovirus types 1 and 2 affecting the Republic of the Philippines and Malaysia, 2019–2021

Author:
Cynthia J. Snider; Liliane Boualam; Graham Tallis; Yoshihiro Takashima; Rabindra Abeyasinghe; Ying-Ru Lo; Varja Grabovac; Tigran Avagyan; Syeda Kanwal Aslam; Abu Obeida Eltayeb; Khin Devi Aung; Xiaojun Wang; Achyut Shrestha; Carla Ante-Orozco; Maria Wilda T. Silva; Nemia Lapastora-Sucaldito; Lea Necitas G. Apostol; Muhammad Bin Hj. Jikal; Waheed Miraj; Faisal Lodhi; Hyung Joon Kim; Norhayati Rusli; Bruce R. Thorley; Matthew B. Kaye; Yorihiro Nishimura; Minetaro Arita; Jamiatul Aida Md. Sani; Christina Rundi; Keith Feldon
Source:
Vaccine 2022 pp. -
ISSN:
0264-410X
Subject:
immunization,   etc   ; COVID-19 infection; Philippines; environmental monitoring; serotypes; sewage; vaccines; viruses; Malaysia;     Show all 9 Subjects
Abstract:
... Concurrent outbreaks of circulating vaccine-derived poliovirus serotypes 1 and 2 (cVDPV1, cVDPV2) were confirmed in the Republic of the Philippines in September 2019 and were subsequently confirmed in Malaysia by early 2020. There is continuous population subgroup movement in specific geographies between the two countries. Outbreak response efforts focused on sequential supplemental immunization a ...
DOI:
10.1016/j.vaccine.2022.02.022

9. Projecting the cost of introducing typhoid conjugate vaccine (TCV) in the national immunization program in Malawi using a standardized costing framework

Author:
Frédéric Debellut; Rouden Mkisi; Vincent Masoo; Mike Chisema; Dennis Mwagomba; Mphatso Mtenje; Fumbani Limani; Donnie Mategula; Boston Zimba; Clint Pecenka
Source:
Vaccine 2022 v.40 no.12 pp. 1741-1746
ISSN:
0264-410X
Subject:
immunization,   etc   ; World Health Organization; children; decision making; funding; typhoid fever; vaccines; Malawi;     Show all 8 Subjects
Abstract:
... There is a substantial typhoid burden in sub-Saharan Africa, and TCV has been introduced in two African countries to date. Decision-makers in Malawi decided to introduce TCV and applied for financial support from Gavi, the Vaccine Alliance in 2020. The current plan is to introduce TCV as part of the national immunization program in late 2022. The introduction will include a nationwide campaign tar ...
DOI:
10.1016/j.vaccine.2022.02.016

10. Review of use of inactivated poliovirus vaccine in campaigns to control type 2 circulating vaccine derived poliovirus (cVDPV) outbreaks

Author:
Concepcion F. Estivariz; Stephanie D. Kovacs; Ondrej Mach
Source:
Vaccine 2022 pp. -
ISSN:
0264-410X
Subject:
immunization,   etc   ; Enterovirus C; humoral immunity; intestines; mucosal immunity; risk; risk reduction; serotypes; vaccines;     Show all 9 Subjects
Abstract:
... Delivering inactivated poliovirus vaccine (IPV) with oral poliovirus vaccine (OPV) in campaigns has been explored to accelerate the control of type 2 circulating vaccine-derived poliovirus (cVDPV) outbreaks. A review of scientific literature suggests that among populations with high prevalence of OPV failure, a booster with IPV after at least two doses of OPV may close remaining humoral and mucosa ...
DOI:
10.1016/j.vaccine.2022.03.027

11. Systematic review and meta-analysis of the effect of pertussis vaccine in pregnancy on the risk of chorioamnionitis, non-pertussis infectious diseases and other adverse pregnancy outcomes

Author:
A.R. Andersen; S.K. Kolmos; K.L. Flanagan; C.S. Benn
Source:
Vaccine 2022 v.40 no.11 pp. 1572-1582
ISSN:
0264-410X
Subject:
immunization,   etc   ; abortion (animals); death; fetal death; infancy; meta-analysis; risk; systematic review; vaccines;     Show all 9 Subjects
Abstract:
... Several countries have introduced maternal immunisation with pertussis vaccine to provide protection against pertussis in early infancy. There is increasing interest in non-specific effects of vaccines including that non-live vaccines may enhance susceptibility to non-targeted infections in females. Some studies have shown increased risk of chorioamnionitis among women receiving pertussis vaccine ...
DOI:
10.1016/j.vaccine.2021.02.018

12. mRNA-1273 or mRNA-Omicron boost in vaccinated macaques elicits similar B cell expansion, neutralizing responses, and protection from Omicron

Author:
Matthew Gagne; Juan I. Moliva; Kathryn E. Foulds; Shayne F. Andrew; Barbara J. Flynn; Anne P. Werner; Danielle A. Wagner; I-Ting Teng; Bob C. Lin; Christopher Moore; Nazaire Jean-Baptiste; Robin Carroll; Stephanie L. Foster; Mit Patel; Madison Ellis; Venkata-Viswanadh Edara; Nahara Vargas Maldonado; Mahnaz Minai; Lauren McCormick; Christopher Cole Honeycutt; Bianca M. Nagata; Kevin W. Bock; Caitlyn N.M. Dulan; Jamilet Cordon; Dillon R. Flebbe; John-Paul M. Todd; Elizabeth McCarthy; Laurent Pessaint; Alex Van Ry; Brandon Narvaez; Daniel Valentin; Anthony Cook; Alan Dodson; Katelyn Steingrebe; Saule T. Nurmukhambetova; Sucheta Godbole; Amy R. Henry; Farida Laboune; Jesmine Roberts-Torres; Cynthia G. Lorang; Shivani Amin; Jessica Trost; Mursal Naisan; Manjula Basappa; Jacquelyn Willis; Lingshu Wang; Wei Shi; Nicole A. Doria-Rose; Yi Zhang; Eun Sung Yang; Kwanyee Leung; Sijy O’Dell; Stephen D. Schmidt; Adam S. Olia; Cuiping Liu; Darcy R. Harris; Gwo-Yu Chuang; Guillaume Stewart-Jones; Isabella Renzi; Yen-Ting Lai; Agata Malinowski; Kai Wu; John R. Mascola; Andrea Carfi; Peter D. Kwong; Darin K. Edwards; Mark G. Lewis; Hanne Andersen; Kizzmekia S. Corbett; Martha C. Nason; Adrian B. McDermott; Mehul S. Suthar; Ian N. Moore; Mario Roederer; Nancy J. Sullivan; Daniel C. Douek; Robert A. Seder
Source:
Cell 2022 v.185 no.9 pp. 1556-1571.e18
ISSN:
0092-8674
Subject:
immunization,   etc   ; B-lymphocytes; Severe acute respiratory syndrome coronavirus 2; immunity; neutralization; virus replication;     Show all 6 Subjects
Abstract:
... SARS-CoV-2 Omicron is highly transmissible and has substantial resistance to neutralization following immunization with ancestral spike-matched vaccines. It is unclear whether boosting with Omicron-matched vaccines would enhance protection. Here, nonhuman primates that received mRNA-1273 at weeks 0 and 4 were boosted at week 41 with mRNA-1273 or mRNA-Omicron. Neutralizing titers against D614G were ...
DOI:
10.1016/j.cell.2022.03.038

13. Invasive Streptococcus pneumoniae isolates from pediatric population in Argentina for the period 2006–2019. Temporal progression of serotypes distribution and antibiotic resistance

Author:
Jonathan Zintgraff; Paula Gagetti; Daniela Napoli; Nahuel Sanchez Eluchans; Lucia Irazu; Maria Moscoloni; Mabel Regueira; Claudia S. Lara; Alejandra Corso; Argentina Spn Working Group
Source:
Vaccine 2022 v.40 no.3 pp. 459-470
ISSN:
0264-410X
Subject:
immunization,   etc   ; Streptococcus pneumoniae; agar; antibiotic resistance; epidemiology; erythromycin; monitoring; morbidity; mortality; serotypes; vaccines; Argentina;     Show all 12 Subjects
Abstract:
... Streptococcus pneumoniae is a major cause of severe invasive disease associated with high mortality and morbidity worldwide. A total of 2908 pneumococcal isolates were analyzed between 2006 and 2019. Gold standard pneumococcal serotyping (the Neufeld-Quellung reaction) was performed to identify the serotypes associated with infection in children < 5 years in Argentina and agar dilution method was ...
DOI:
10.1016/j.vaccine.2021.12.008

14. Population immunity to measles in Canada using Canadian Health Measures survey data – A Canadian Immunization Research Network (CIRN) study

Author:
Selma Osman; Natasha Crowcroft; Elizabeth McLachlan; Todd Hatchette; Carol Perez-Iratxeta; Eugene Joh; James Wright; Scott A. Halperin; Shelley Deeks; Sarah Wilson; Sarah Buchan; Brian Ward; Jonathan Gubbay; Marc Brisson; Bouchra Serhir; Alberto Severini; Shelly Bolotin
Source:
Vaccine 2022 v.40 no.23 pp. 3228-3235
ISSN:
0264-410X
Subject:
immunization,   etc   ; adults; confidence interval; immunity; measles; neutralization tests; risk assessment; seroprevalence; surveys; vaccines; Canada;     Show all 11 Subjects
Abstract:
... We aimed to determine population immunity to measles in Canada, and to assess the risk of future outbreaks. We tested 11,176 sera from Cycles 2 (2009–2011) and 3 (2011–2013) cohorts from the biobank of Statistics Canada’s Canadian Health Measures Survey (CHMS) using the BioPlex 2220 MMRV IgG assay. We then tested all BioPlex negative and equivocal samples using a more sensitive Plaque Reduction Ne ...
DOI:
10.1016/j.vaccine.2022.04.011

15. Production of an in-House Rabbit Anti-Camel Immunoglobulin G (IgG) Conjugated With Horseradish Peroxidase (HRP) For Use in Immunoblots

Author:
Sabry M. El-Bahr; M.M. El Hassan
Source:
Journal of camel practice and research 2022 v.29 no.1 pp. 17-23
ISSN:
2277-8934
Subject:
immunization,   etc   ; Haemonchus; blood serum; camels; electrophoresis; immunoblotting; immunoglobulin G; molecular weight; peroxidase; rabbits; research;     Show all 11 Subjects
Abstract:
... The present study was aimed to develop anti-camel immunoglobulin G (IgG) conjugate. Camel serum was obtained from healthy camels and the IgG was extracted from this serum using the commercially available IgG purification kits. The electrophoretic profile of camel IgG showed four bands of molecular weight 66, 50, 44 and 33 kDa. Two rabbits were immunised with the purified camel IgG for production o ...
DOI:
10.5958/2277-8934.2022.00003.0

16. Chitosan based nanoformulation expressing miR-155 as a promising adjuvant to enhance Th1-biased immune responses

Author:
Mehrnoush Safarzadeh; Samira Mohammadi-Yeganeh; Fatemeh Ghorbani-Bidkorbeh; Mostafa Haji Molla Hoseini
Source:
Life sciences 2022 v.297 pp. 120459
ISSN:
0024-3205
Subject:
immunization,   etc   ; T-lymphocytes; adjuvants; antigens; chitosan; electrophoresis; interleukin-4; ovalbumin; plasmids; splenocytes; transfection; zeta potential;     Show all 12 Subjects
Abstract:
... MiR-155 could act as a key modulator of different aspects of immune system including Th1 responses. In this study, we designed chitosan nanoparticles containing miR-155-expressing plasmid and explored their effects as an adjuvant to enhance Th1 responses for potential future application against intracellular pathogens. Nanoparticles were formulated by complex coacervation method and characterized ...
DOI:
10.1016/j.lfs.2022.120459

17. Efficacy of immunization with a recombinant S. aureus vaccine formulated with liposomes and ODN-CpG against natural S. aureus intramammary infections in heifers and cows

Author:
C.M. Camussone; I.G. Reidel; A.I. Molineri; J. Cicotello; C. Miotti; G.A. Suarez Archilla; C.C. Curti; C. Veaute; L.F. Calvinho
Source:
Research in veterinary science 2022 v.145 pp. 177-187
ISSN:
0034-5288
Subject:
immunization,   etc   ; antibody formation; disease incidence; hemolysis; immunoglobulin G; milk; oligodeoxyribonucleotides; research; subunit vaccines; veterinary medicine;     Show all 10 Subjects
Abstract:
... The aims of the present study were to evaluate the ability of a subunit vaccine composed of recombinant molecules of α-toxin, β-toxin, FnBPA and ClfA, formulated with cationic liposomes and CpG-ODN, to confer protection against natural S. aureus intramammary infection (IMI) and to assess the antibody response against the vaccine components. A stringent criterion based on molecular identification o ...
DOI:
10.1016/j.rvsc.2022.02.014

18. Impact of the COVID-19 pandemic on routine immunization coverage in children under 2 years old in Ontario, Canada: A retrospective cohort study

Author:
Catherine Ji; Pierre-Philippe Piché-Renaud; Jemisha Apajee; Ellen Stephenson; Milena Forte; Jeremy N. Friedman; Michelle Science; Stanley Zlotkin; Shaun K. Morris; Karen Tu
Source:
Vaccine 2022 v.40 no.12 pp. 1790-1798
ISSN:
0264-410X
Subject:
immunization,   etc   ; COVID-19 infection; childhood; cohort studies; databases; medical records; pandemic; public health; vaccines; Ontario;     Show all 10 Subjects
Abstract:
... The COVID-19 pandemic has caused a disruption in childhood immunization coverage around the world. This study aimed to determine the change in immunization coverage for children under 2 years old in Ontario, Canada, comparing time periods pre-pandemic to during the first year of the pandemic. Observational retrospective open cohort study, using primary care electronic medical record data from the ...
DOI:
10.1016/j.vaccine.2022.02.008

19. NIR-Responsive Photodynamic Nanosystem Combined with Antitumor Immune Optogenetics Bacteria for Precise Synergetic Therapy

Author:
Changsong Wu; Meihui Cui; Li Cai; Chen Chen; Xiaohui Zhu; Yihan Wu; Jinliang Liu; Hanjie Wang; Yong Zhang
Source:
ACS applied materials & interfaces 2022 v.14 no.11 pp. 13094-13106
ISSN:
1944-8252
Subject:
immunization,   etc   ; erbium; hypoxia; immune response; immune system; intestines; metastasis; neoplasms; optogenetics; photochemotherapy; photosensitizing agents; thulium;     Show all 12 Subjects
Abstract:
... Photodynamic therapy (PDT) and immunotherapy are considered promising methods for the treatment of tumors. However, these treatment systems are still suffering from shortcomings such as hypoxia, easy metastasis, and delayed immune response during PDT. Therefore, it is still challenging to establish a programmed and rapid response immune combination therapy platform. Here, we construct a two-step s ...
DOI:
10.1021/acsami.2c01138

20. Rectifying cow infertility under heat stress by immunization against inhibin and supplementation of progesterone

Author:
F. Chen; J. Lu; R. Guo; C. Mei; B. Guo; W. Li; A. Tsigkou; Z. Shi
Source:
Domestic animal endocrinology 2022 v.80 pp. 106726
ISSN:
0739-7240
Subject:
immunization,   etc   ; Holstein; additive effect; blood; conception rate; heat stress; inhibin; ovarian follicles; pregnancy; progesterone; weather;     Show all 11 Subjects
Abstract:
... This study was undertaken for the development of novel techniques that are based on immunoneutralization of inhibin bioactivity to improve Holstein cow fertility. A series of 4 experiments were carried out on 2 farms that were located in subtropical or temperate regions, to test the effects of immunization against inhibin alpha subunit on cow fertility under varying degrees of heat stress conditio ...
DOI:
10.1016/j.domaniend.2022.106726