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Enrique Pino Martinez; Pablo Balseiro; Sigurd O. Stefansson; Nobuto Kaneko; Birgitta Norberg; Mitchell S. Fleming; Albert K.D. Imsland; Sigurd O. Handeland
insulin-likegrowthfactorI, etc ; Salmo salar; adenosinetriphosphatase; aquaculture; early development; genes; gonadosomatic index; life history; males; parr; photoperiod; restricted feeding; risk; salmon; seawater; smoltification; temperature; Show all 17 Subjects
Abstract:
... Early maturation of Atlantic salmon male postsmolts is undesirable in aquaculture due to its negative impact on growth, welfare and seawater adaptation, however it is an increasing problem under intensive rearing conditions. The effect of temperature and feeding ration on sexual maturation during the induction of smoltification was tested with a 3 × 2 factorial design including three temperatures ...
... The recirculating pond aquaculture system (RPAS) consisted of culture ponds, a purification pond, inflow ditch, outflow pipe, ecological ditch, and electrically driven pump. The performance of RPAS on grass carp (Ctenopharyngodon idellus) was explored in this study. In both the RPAS and the traditional pond aquaculture system (TPAS), water quality, fish growth performance, muscle quality, and tiss ...
insulin-likegrowthfactorI; insulin-likegrowthfactorI receptor, etc ; bile ducts; histopathology; immune response; liver cirrhosis; muscle fibers; muscles; skeletal muscle; surgery; Show all 10 Subjects
Abstract:
... We investigated the expression of insulin-like growth factor 1 (IGF-1) and IGF-1 type 1 receptor (IGF-1R) in skeletal muscle fiber types in chickens with hepatic fibrosis induced by bile duct ligation (BDL). Eleven hens, approximately 104 weeks old, were randomly assigned to BDL (n = 4) and sham surgery (SHAM; n = 7) groups. In BDL hens, histopathology revealed marked bile duct proliferation and l ...
insulin-likegrowthfactorI, etc ; lycopene; phytotherapy; research; systematic review; Show all 5 Subjects
Abstract:
... Lycopene has been posited to regulate insulin‐like growth factor‐1 (IGF‐1). We aimed to conduct a systematic review of the effects of lycopene on circulating IGF‐1 and insulin‐like growth factor binding proteins (IGFBPs) in adults. A systematic search was carried out in PubMed, Scopus, ISI Web of Science, and the Cochrane Library databases for randomized controlled trials (RCTs), published from in ...
insulin-likegrowthfactorI receptor, etc ; Caenorhabditis elegans; apoptosis; biomarkers; cell proliferation; genes; hematopoiesis; microRNA; Show all 8 Subjects
Abstract:
... In 1993, the discovery of microRNAs in Caenorhabditis elegans (C. elegans) altered the paradigmatic view of RNA biology and post-transcriptional gene regulation. Further study revealed the role of microRNAs in disease development and progression. In particular, this review highlights microRNA-223 (miR-223 or miRNA-223) expression in malignant neoplastic disorders. miR-223 expression controls aspec ...
insulin-likegrowthfactorI, etc ; automation; biocompatible materials; biofabrication; composite polymers; drugs; extrusion; hydrogels; medicine; metalloproteinases; Show all 10 Subjects
Abstract:
... 3D printing of biomaterials enables spatial control of drug incorporation during automated manufacturing. This study links bioresponsive release of the anabolic biologic, insulin-like growth factor-I (IGF-I) in response to matrix metalloproteinases (MMP) to 3D printing using the block copolymer of poly(2-methyl-2-oxazoline) and thermoresponsive poly(2-n-propyl-2-oxazine) (POx-b-POzi). For that, a ...
Wenda Cui; Eisuke Takahashi; Bernat Morro; Pablo Balseiro; Amaya Albalat; Cindy Pedrosa; Simon Mackenzie; Tom O. Nilsen; Harald Sveier; Lars O. Ebbesson; Sigurd O. Handeland; Munetaka Shimizu
insulin-likegrowthfactorI, etc ; Oncorhynchus mykiss; body size; fish; photoperiod; satiety; smoltification; somatotropin; spring; yearlings; Show all 10 Subjects
Abstract:
... Smoltification in salmonids occurs during spring in response to increasing photoperiod to prepare for marine life. Smoltification is associated with increased hypo-osmoregulatory ability and enhanced growth potential, mediated by growth hormone and insulin-like growth factor (IGF)-1. Rainbow trout is uniquely insensitive to the induction of smoltification-associated changes by photoperiod, such as ...
insulin-likegrowthfactorI, etc ; alginates; culture media; follicular development; intraperitoneal injection; mice; oocytes; progesterone; superovulation; Show all 9 Subjects
Abstract:
... Insulin-like growth factor-1 (IGF-1) plays a crucial role during folliculogenesis, which has been demonstrated by previous research. However, the optimal IGF-1 dosage in the three-dimensional (3D) culture system is unknown. Mouse secondary follicles (140–150 µm) were cultured for 6 days within an alginate bead in a medium supplemented with 0 (G0), 5 ng/mL (G5), 10 ng/mL (G10), or 50 ng/mL IGF-1 (G ...
insulin-likegrowthfactorI receptor, etc ; Escherichia coli; body weight changes; hypothalamus; iturin; pork; semimembranosus muscle; Show all 7 Subjects
Abstract:
... The engineered STb-Rosetta Escherichia coli (STb-R) was designed to investigate the effects of Iturin A on the skeletal muscle growth of weaned piglets. A total of 28 piglets were randomly divided into 4 groups (7 piglets per group): the control group (100 mL PBS), the Iturin A group (100 mL 320 mg/kg body weight (BW) Iturin A), the STb-R group (100 mL 1 × 10¹⁰ CFU/mL STb-R), and the Iturin A + ST ...
insulin-likegrowthfactorI, etc ; Fusarium; androstenedione; cattle; cell proliferation; estradiol; grapes; mycotoxins; myricetin; progesterone; red wines; steroidogenesis; toxicology; Show all 13 Subjects
Abstract:
... Myricetin (a flavonol) and piceatannol (a stilbenoid) are naturally occurring phenolic compounds in red wine with cardio-protective and anti-carcinogenic effects, but their potential reproductive effects have not been investigated. Thus, the present study was designed to determine if myricetin and piceatannol can directly affect ovarian function using bovine granulosa cells (GC) and theca cells (T ...
insulin-likegrowthfactorI, etc ; Holstein; cattle; epithelium; glucose; insulin; milk proteins; phosphorylation; prolactin; protein synthesis; proteome; proteomics; somatotropin; Show all 13 Subjects
Abstract:
... Milk protein concentrations in dairy cows are considered to be related to some plasma biomolecules. However, the characteristics of plasma biomolecules in dairy cows with different long-term milk protein concentrations are not fully elucidated. This study was conducted to understand the mechanism of plasma proteins in milk protein synthesis by the comparative analysis of the plasma proteomics of c ...
insulin-likegrowthfactorI, etc ; bioclimatology; blood serum; interleukin-1beta; osteoarthritis; pain; patients; questionnaires; therapeutics; tumor necrosis factor-alpha; Ontario; Show all 11 Subjects
Abstract:
... The purpose of this study was to investigate the therapeutic and the chemical effects of balneological treatment (peloidotherapy + hydrotherapy), and its effects on serum levels of interleukin-1beta (IL-1β), tumor necrosis factor-alpha (TNF-α), and insulin-like growth factor–1 (IGF-1) in patients with knee osteoarthritis (OA). Sixty-four (64) knee OA patients were randomly divided into study and c ...
insulin-likegrowthfactorI, etc ; Chinese people; alleles; chi-square distribution; gelatinase B; genetic disorders; genotype; genotyping; loci; models; myopia; Show all 11 Subjects
Abstract:
... High myopia is a common ocular genetic disease in the world. The study sought to investigate the effect of the Insulin-like growth factor-1 (IGF-1) and Matrix metalloproteinase-9 (MMP-9) genes polymorphisms on high myopia in a Han population of China. This study recruited 216 unrelated Han Chinese subjects, including 103 cases with high myopia and 113 controls. Four tagging single nucleotide polym ...
insulin-likegrowthfactorI, etc ; agriculture; bone morphogenetic proteins; diet; fibroblast growth factors; fur; hair follicles; heat; heat stress; vitamin A; Show all 10 Subjects
Abstract:
... BACKGROUND: Rex rabbits are important fur rabbits. Heat stress severely reduces the fur quality of Rex rabbits. The aim of this study was to experimentally investigate the effect of dietary vitamin A (VA) addition on hair follicle development and related signal pathways in Rex rabbits under heat stress. RESULTS: In the experiment, 90 Rex rabbits were randomly divided into three groups: control gro ...
Mohamad-Reza Aghanoori; Prasoon Agarwal; Evan Gauvin; Raghu S. Nagalingam; Raiza Bonomo; Vinith Yathindranath; Darrell R. Smith; Yan Hai; Samantha Lee; Corinne G. Jolivalt; Nigel A. Calcutt; Meaghan J. Jones; Michael P. Czubryt; Donald W. Miller; Vernon W. Dolinsky; Virginie Mansuy-Aubert; Paul Fernyhough
... Aberrant insulin-like growth factor 1 (IGF-1) signaling has been proposed as a contributing factor to the development of neurodegenerative disorders including diabetic neuropathy, and delivery of exogenous IGF-1 has been explored as a treatment for Alzheimer’s disease and amyotrophic lateral sclerosis. However, the role of autocrine/paracrine IGF-1 in neuroprotection has not been well established. ...
insulin-likegrowthfactorI receptor, etc ; androgen receptors; clinical examination; cross-sectional studies; insulin receptors; males; metabolism; quality of life; surgery; Show all 9 Subjects
Abstract:
... Peripheral artery disease (PAD) of the lower limbs is a common condition that can affect quality of life. Androgen receptor (AR) can exert sex-specific effects on metabolic system, endothelial function and vascular tone. IGF-I receptor (IGF-IR) and insulin receptor (IR) may also be involved in the aforementioned functions. The aim of this study was to evaluate AR, IGF-IR and IR expression in the a ...
insulin-likegrowthfactorI, etc ; Serinus canaria; antioxidant activity; color; egg masses; eggs; energy; females; food availability; hematocrit; life history; resource allocation; Show all 12 Subjects
Abstract:
... Environmental challenges, such as fluctuations in food availability, could influence reproductive investment. If resource availability is poor, individuals need to decide in which life‐history process they invest more energy and vital compounds, which determine the cost of reproduction. In resource allocation, the physiological pathways have important roles. The aim of our study was to examine whe ...
Putri Nur Hidayah Al-Zikri; Tee Jong Huat; Amir Ali Khan; Azim Patar; Mohammed Faruque Reza; Fauziah Mohamad Idris; Jafri Malin Abdullah; Hasnan Jaafar
... Bone marrow-derived mesenchymal stem cells (BMSCs) have therapeutic potential for spinal cord injury (SCI). We have shown that insulin-like growth factor 1 (IGF-1) enhances the cellular proliferation and survivability of BMSCs-derived neural progenitor cells (NPCs) by downregulating miR-22-3p. However, the functional application of BMSCs-derived NPCs has not been investigated fully. In this study, ...
Oro Uchenunu; Alexander V. Zhdanov; Phillipe Hutton; Predrag Jovanovic; Ye Wang; Dmitry E. Andreev; Laura Hulea; David J. Papadopoli; Daina Avizonis; Pavel V. Baranov; Michael N. Pollak; Dmitri B. Papkovsky; Ivan Topisirovic
... Mutations in genes encoding cytochrome c oxidase (mitochondrial complex IV) subunits and assembly factors [e.g., synthesis of cytochrome c oxidase 2 (SCO2)] are linked to severe metabolic syndromes. Notwithstanding that SCO2 is under transcriptional control of tumor suppressor p53, the role of mitochondrial complex IV dysfunction in cancer metabolism remains obscure. Herein, we demonstrate that th ...
... The severity and fatality of Coronavirus disease 2019 (COVID-19) infection are not the same in the infected population. The host immune response and Immune-stimulating factors appear to play a role in COVID-19 infection outcome. insulin-like growth factor-1 (IGF-1) affects the immune system by controlling the endocrine system. Recently, the effect of IGF-1 levels on COVID-19 prognosis has been con ...