U.S. flag

An official website of the United States government

Dot gov

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Https

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

PubAg

Main content area

You searched for: Subject "insulin-like growth factor I" Remove constraint Subject: "insulin-like growth factor I"
Start Over

Search

3,182  Search Results

« Previous | 1 - 20 of 3,182 |
Number of results to display per page

Search Results

1. Interaction of temperature and feed ration on male postsmolt maturation of Atlantic salmon (Salmo salar L.)

Author:
Enrique Pino Martinez; Pablo Balseiro; Sigurd O. Stefansson; Nobuto Kaneko; Birgitta Norberg; Mitchell S. Fleming; Albert K.D. Imsland; Sigurd O. Handeland
Source:
Aquaculture 2023 v.562 pp. 738877
ISSN:
0044-8486
Subject:
insulin-like growth factor I,   etc   ; Salmo salar; adenosinetriphosphatase; aquaculture; early development; genes; gonadosomatic index; life history; males; parr; photoperiod; restricted feeding; risk; salmon; seawater; smoltification; temperature;     Show all 17 Subjects
Abstract:
... Early maturation of Atlantic salmon male postsmolts is undesirable in aquaculture due to its negative impact on growth, welfare and seawater adaptation, however it is an increasing problem under intensive rearing conditions. The effect of temperature and feeding ration on sexual maturation during the induction of smoltification was tested with a 3 × 2 factorial design including three temperatures ...
DOI:
10.1016/j.aquaculture.2022.738877

2. The growth performance, antioxidative status and muscle quality of grass carp (Ctenopharyngodon idellus) cultured in the recirculating pond aquaculture system (RPAS)

Author:
Weitong Xu; Qiushi Yang; Yin Wang; Rong Tang; Dapeng Li
Source:
Aquaculture 2023 v.562 pp. 738829
ISSN:
0044-8486
Subject:
insulin-like growth factor I,   etc   ; Ctenopharyngodon idella; ammonium nitrogen; animal growth; aquaculture; aquatic plants; aspartic acid; blood serum; feed conversion; fish; genes; glutamic acid; growth performance; histology; insulin-like growth factor II; liver; malondialdehyde; muscles; myogenin; nitrate nitrogen; oxidative stress; somatotropin receptors; texture; umami; water quality;     Show all 25 Subjects
Abstract:
... The recirculating pond aquaculture system (RPAS) consisted of culture ponds, a purification pond, inflow ditch, outflow pipe, ecological ditch, and electrically driven pump. The performance of RPAS on grass carp (Ctenopharyngodon idellus) was explored in this study. In both the RPAS and the traditional pond aquaculture system (TPAS), water quality, fish growth performance, muscle quality, and tiss ...
DOI:
10.1016/j.aquaculture.2022.738829

3. Research Note: Expression of IGF-1 and IGF-1 receptor proteins in skeletal muscle fiber types in chickens with hepatic fibrosis

Author:
J. Nagasao; H. Fukasawa; K. Yoshioka; N. Fujimura; M. Kobayashi; Y. Tsunemi; A. Nomoto; S. Mitsui; H. Murata; I. Yokoyama; Y. Komiya; K. Arihara
Source:
Poultry science 2022 v.101 no.10 pp. 102045
ISSN:
0032-5791
Subject:
insulin-like growth factor I; insulin-like growth factor I receptor,   etc   ; bile ducts; histopathology; immune response; liver cirrhosis; muscle fibers; muscles; skeletal muscle; surgery;     Show all 10 Subjects
Abstract:
... We investigated the expression of insulin-like growth factor 1 (IGF-1) and IGF-1 type 1 receptor (IGF-1R) in skeletal muscle fiber types in chickens with hepatic fibrosis induced by bile duct ligation (BDL). Eleven hens, approximately 104 weeks old, were randomly assigned to BDL (n = 4) and sham surgery (SHAM; n = 7) groups. In BDL hens, histopathology revealed marked bile duct proliferation and l ...
DOI:
10.1016/j.psj.2022.102045

4. The effects of lycopene supplementation on insulin‐like growth factor‐1 and insulin‐like growth factor binding proteins: A systematic review of randomized controlled trials

Author:
Fatemeh Meshkini; Nahid Ramezani‐Jolfaie; Saman Sargazi; Cain C.T. Clark; Sepideh Soltani
Source:
Phytotherapy research 2022 v.36 no.4 pp. 1633-1643
ISSN:
0951-418X
Subject:
insulin-like growth factor I,   etc   ; lycopene; phytotherapy; research; systematic review;     Show all 5 Subjects
Abstract:
... Lycopene has been posited to regulate insulin‐like growth factor‐1 (IGF‐1). We aimed to conduct a systematic review of the effects of lycopene on circulating IGF‐1 and insulin‐like growth factor binding proteins (IGFBPs) in adults. A systematic search was carried out in PubMed, Scopus, ISI Web of Science, and the Cochrane Library databases for randomized controlled trials (RCTs), published from in ...
DOI:
10.1002/ptr.7418

5. Relevance of miR-223 as Potential Diagnostic and Prognostic Markers in Cancer

Author:
Faisal Aziz; Abhijit Chakraborty; Imran Khan; Josh Monts
Source:
Biology 2022 v.11 no.2 pp. -
ISSN:
2079-7737
Subject:
insulin-like growth factor I receptor,   etc   ; Caenorhabditis elegans; apoptosis; biomarkers; cell proliferation; genes; hematopoiesis; microRNA;     Show all 8 Subjects
Abstract:
... In 1993, the discovery of microRNAs in Caenorhabditis elegans (C. elegans) altered the paradigmatic view of RNA biology and post-transcriptional gene regulation. Further study revealed the role of microRNAs in disease development and progression. In particular, this review highlights microRNA-223 (miR-223 or miRNA-223) expression in malignant neoplastic disorders. miR-223 expression controls aspec ...
DOI:
10.3390/biology11020249

6. Merging bioresponsive release of insulin-like growth factor I with 3D printable thermogelling hydrogels

Author:
Matthias Beudert; Lukas Hahn; Anselm H.C. Horn; Niklas Hauptstein; Heinrich Sticht; Lorenz Meinel; Robert Luxenhofer; Marcus Gutmann; Tessa Lühmann
Source:
Journal of controlled release 2022 v.347 pp. 115-126
ISSN:
0168-3659
Subject:
insulin-like growth factor I,   etc   ; automation; biocompatible materials; biofabrication; composite polymers; drugs; extrusion; hydrogels; medicine; metalloproteinases;     Show all 10 Subjects
Abstract:
... 3D printing of biomaterials enables spatial control of drug incorporation during automated manufacturing. This study links bioresponsive release of the anabolic biologic, insulin-like growth factor-I (IGF-I) in response to matrix metalloproteinases (MMP) to 3D printing using the block copolymer of poly(2-methyl-2-oxazoline) and thermoresponsive poly(2-n-propyl-2-oxazine) (POx-b-POzi). For that, a ...
DOI:
10.1016/j.jconrel.2022.04.028

7. Changes in circulating insulin-like growth factor-1 and its binding proteins in yearling rainbow trout during spring under natural and manipulated photoperiods and their relationships with gill Na+, K+-ATPase and body size

Author:
Wenda Cui; Eisuke Takahashi; Bernat Morro; Pablo Balseiro; Amaya Albalat; Cindy Pedrosa; Simon Mackenzie; Tom O. Nilsen; Harald Sveier; Lars O. Ebbesson; Sigurd O. Handeland; Munetaka Shimizu
Source:
Comparative biochemistry and physiology 2022 v.268 pp. 111205
ISSN:
1095-6433
Subject:
insulin-like growth factor I,   etc   ; Oncorhynchus mykiss; body size; fish; photoperiod; satiety; smoltification; somatotropin; spring; yearlings;     Show all 10 Subjects
Abstract:
... Smoltification in salmonids occurs during spring in response to increasing photoperiod to prepare for marine life. Smoltification is associated with increased hypo-osmoregulatory ability and enhanced growth potential, mediated by growth hormone and insulin-like growth factor (IGF)-1. Rainbow trout is uniquely insensitive to the induction of smoltification-associated changes by photoperiod, such as ...
DOI:
10.1016/j.cbpa.2022.111205

8. Effects of IGF-1 on the Three-Dimensional Culture of Ovarian Preantral Follicles and Superovulation Rates in Mice

Author:
Shizhen Dai; Hanxue Zhang; Feng Yang; Wei Shang; Shenming Zeng
Source:
Biology 2022 v.11 no.6 pp. -
ISSN:
2079-7737
Subject:
insulin-like growth factor I,   etc   ; alginates; culture media; follicular development; intraperitoneal injection; mice; oocytes; progesterone; superovulation;     Show all 9 Subjects
Abstract:
... Insulin-like growth factor-1 (IGF-1) plays a crucial role during folliculogenesis, which has been demonstrated by previous research. However, the optimal IGF-1 dosage in the three-dimensional (3D) culture system is unknown. Mouse secondary follicles (140–150 µm) were cultured for 6 days within an alginate bead in a medium supplemented with 0 (G0), 5 ng/mL (G5), 10 ng/mL (G10), or 50 ng/mL IGF-1 (G ...
DOI:
10.3390/biology11060833

9. Iturin A Rescued STb-R-Induced Pork Skeletal Muscle Growth Restriction through the Hypothalamic-Pituitary-mTORC1 Growth Axis

Author:
Mao Ye; Zhenhua Liu; Chunqi Gao; Huichao Yan; Xiuqi Wang; Liufa Wen; Chenglong Jin
Source:
Animals 2022 v.12 no.12 pp. -
ISSN:
2076-2615
Subject:
insulin-like growth factor I receptor,   etc   ; Escherichia coli; body weight changes; hypothalamus; iturin; pork; semimembranosus muscle;     Show all 7 Subjects
Abstract:
... The engineered STb-Rosetta Escherichia coli (STb-R) was designed to investigate the effects of Iturin A on the skeletal muscle growth of weaned piglets. A total of 28 piglets were randomly divided into 4 groups (7 piglets per group): the control group (100 mL PBS), the Iturin A group (100 mL 320 mg/kg body weight (BW) Iturin A), the STb-R group (100 mL 1 × 10¹⁰ CFU/mL STb-R), and the Iturin A + ST ...
DOI:
10.3390/ani12121568

10. Effects of grape phenolics, myricetin and piceatannol, on bovine granulosa and theca cell proliferation and steroid production in vitro

Author:
Leon J. Spicer; Luis F. Schütz
Source:
Food and chemical toxicology 2022 v.167 pp. 113288
ISSN:
0278-6915
Subject:
insulin-like growth factor I,   etc   ; Fusarium; androstenedione; cattle; cell proliferation; estradiol; grapes; mycotoxins; myricetin; progesterone; red wines; steroidogenesis; toxicology;     Show all 13 Subjects
Abstract:
... Myricetin (a flavonol) and piceatannol (a stilbenoid) are naturally occurring phenolic compounds in red wine with cardio-protective and anti-carcinogenic effects, but their potential reproductive effects have not been investigated. Thus, the present study was designed to determine if myricetin and piceatannol can directly affect ovarian function using bovine granulosa cells (GC) and theca cells (T ...
DOI:
10.1016/j.fct.2022.113288

11. Plasma Proteomic Profiling Reveals the Regulatory Factors of Milk Protein Synthesis in Holstein Cows

Author:
Xinling Wang; Jie Xu; Zhaoyu Han
Source:
Biology 2022 v.11 no.8 pp. -
ISSN:
2079-7737
Subject:
insulin-like growth factor I,   etc   ; Holstein; cattle; epithelium; glucose; insulin; milk proteins; phosphorylation; prolactin; protein synthesis; proteome; proteomics; somatotropin;     Show all 13 Subjects
Abstract:
... Milk protein concentrations in dairy cows are considered to be related to some plasma biomolecules. However, the characteristics of plasma biomolecules in dairy cows with different long-term milk protein concentrations are not fully elucidated. This study was conducted to understand the mechanism of plasma proteins in milk protein synthesis by the comparative analysis of the plasma proteomics of c ...
DOI:
10.3390/biology11081239

12. Evaluation of the therapeutic and the chemical effects of balneological treatment on clinical and laboratory parameters in knee osteoarthritis: a randomized, controlled, single-blinded trial

Author:
Tuba Adıgüzel; Beyza Arslan; Hatice Gürdal; M. Zeki Karagülle
Source:
International journal of biometeorology 2022 v.66 no.6 pp. 1257-1265
ISSN:
0020-7128
Subject:
insulin-like growth factor I,   etc   ; bioclimatology; blood serum; interleukin-1beta; osteoarthritis; pain; patients; questionnaires; therapeutics; tumor necrosis factor-alpha; Ontario;     Show all 11 Subjects
Abstract:
... The purpose of this study was to investigate the therapeutic and the chemical effects of balneological treatment (peloidotherapy + hydrotherapy), and its effects on serum levels of interleukin-1beta (IL-1β), tumor necrosis factor-alpha (TNF-α), and insulin-like growth factor–1 (IGF-1) in patients with knee osteoarthritis (OA). Sixty-four (64) knee OA patients were randomly divided into study and c ...
DOI:
10.1007/s00484-022-02274-6

13. Genetic susceptibility to high myopia in Han Chinese population

Author:
Yufei Li; Yong Zhang; Ping Zhang; Lei Gao; Qingyue Ma; Jin Li; Shengxia Wang; Bing Liu; Xinye Wang; Chao Meng
Source:
Open life sciences 2022 v.17 no.1 pp. 512-516
ISSN:
2391-5412
Subject:
insulin-like growth factor I,   etc   ; Chinese people; alleles; chi-square distribution; gelatinase B; genetic disorders; genotype; genotyping; loci; models; myopia;     Show all 11 Subjects
Abstract:
... High myopia is a common ocular genetic disease in the world. The study sought to investigate the effect of the Insulin-like growth factor-1 (IGF-1) and Matrix metalloproteinase-9 (MMP-9) genes polymorphisms on high myopia in a Han population of China. This study recruited 216 unrelated Han Chinese subjects, including 103 cases with high myopia and 113 controls. Four tagging single nucleotide polym ...
DOI:
10.1515/biol-2022-0055

14. Vitamin A alleviates heat stress‐induced damage to hair follicle development in Rex rabbits

Author:
Zhengkai Yue; Chenyang Li; Yongxu Liu; Mengqi Liu; Man Zhao; Fuchang Li; Lei Liu
Source:
Journal of the science of food and agriculture 2022 v.102 no.6 pp. 2291-2299
ISSN:
0022-5142
Subject:
insulin-like growth factor I,   etc   ; agriculture; bone morphogenetic proteins; diet; fibroblast growth factors; fur; hair follicles; heat; heat stress; vitamin A;     Show all 10 Subjects
Abstract:
... BACKGROUND: Rex rabbits are important fur rabbits. Heat stress severely reduces the fur quality of Rex rabbits. The aim of this study was to experimentally investigate the effect of dietary vitamin A (VA) addition on hair follicle development and related signal pathways in Rex rabbits under heat stress. RESULTS: In the experiment, 90 Rex rabbits were randomly divided into three groups: control gro ...
DOI:
10.1002/jsfa.11567

15. CEBPβ regulation of endogenous IGF-1 in adult sensory neurons can be mobilized to overcome diabetes-induced deficits in bioenergetics and axonal outgrowth

Author:
Mohamad-Reza Aghanoori; Prasoon Agarwal; Evan Gauvin; Raghu S. Nagalingam; Raiza Bonomo; Vinith Yathindranath; Darrell R. Smith; Yan Hai; Samantha Lee; Corinne G. Jolivalt; Nigel A. Calcutt; Meaghan J. Jones; Michael P. Czubryt; Donald W. Miller; Vernon W. Dolinsky; Virginie Mansuy-Aubert; Paul Fernyhough
Source:
Cellular and molecular life sciences 2022 v.79 no.4 pp. 193
ISSN:
1420-682X
Subject:
insulin-like growth factor I; insulin-like growth factor I receptor,   etc   ; RNA; adults; aldehyde reductase; amyotrophic lateral sclerosis; autocrine signaling; brain; cell culture; cortex; diabetic neuropathy; energy metabolism; high carbohydrate diet; hybridization; hyperglycemia; liver; mitochondria; nerve tissue; neurites; neuroprotective effect; noninsulin-dependent diabetes mellitus; satellites; streptozotocin; therapeutics; transcription (genetics);     Show all 25 Subjects
Abstract:
... Aberrant insulin-like growth factor 1 (IGF-1) signaling has been proposed as a contributing factor to the development of neurodegenerative disorders including diabetic neuropathy, and delivery of exogenous IGF-1 has been explored as a treatment for Alzheimer’s disease and amyotrophic lateral sclerosis. However, the role of autocrine/paracrine IGF-1 in neuroprotection has not been well established. ...
DOI:
10.1007/s00018-022-04201-9

16. Assessment of androgen receptor, IGF-IR and insulin receptor expression in male patients with severe peripheral artery disease

Author:
Michele Andreucci; Damiano Cosimo Rigiracciolo; Umberto Marcello Bracale; Nicola Ielapi; Michele Provenzano; Diletta D'Iuorno; Ashour Michael; Pasquale Mastroroberto; Giuseppe Filiberto Serraino; Marcello Maggiolini; Raffaele Serra
Source:
Heliyon 2022 v.8 no.1 pp. e08756
ISSN:
2405-8440
Subject:
insulin-like growth factor I receptor,   etc   ; androgen receptors; clinical examination; cross-sectional studies; insulin receptors; males; metabolism; quality of life; surgery;     Show all 9 Subjects
Abstract:
... Peripheral artery disease (PAD) of the lower limbs is a common condition that can affect quality of life. Androgen receptor (AR) can exert sex-specific effects on metabolic system, endothelial function and vascular tone. IGF-I receptor (IGF-IR) and insulin receptor (IR) may also be involved in the aforementioned functions. The aim of this study was to evaluate AR, IGF-IR and IR expression in the a ...
DOI:
10.1016/j.heliyon.2022.e08756

17. Food restriction delays breeding and affects insulin‐like growth factor‐1, oxidative damage and haematocrit value before egg‐laying in female canaries

Author:
Rita Hargitai; Nóra Boross; Zsófia Tóth; Ádám Z. Lendvai
Source:
Journal of avian biology 2022 v.2022 no.4 pp. e02866
ISSN:
0908-8857
Subject:
insulin-like growth factor I,   etc   ; Serinus canaria; antioxidant activity; color; egg masses; eggs; energy; females; food availability; hematocrit; life history; resource allocation;     Show all 12 Subjects
Abstract:
... Environmental challenges, such as fluctuations in food availability, could influence reproductive investment. If resource availability is poor, individuals need to decide in which life‐history process they invest more energy and vital compounds, which determine the cost of reproduction. In resource allocation, the physiological pathways have important roles. The aim of our study was to examine whe ...
DOI:
10.1111/jav.02866

18. Transplantation of IGF-1-induced BMSC-derived NPCs promotes tissue repair and motor recovery in a rat spinal cord injury model

Author:
Putri Nur Hidayah Al-Zikri; Tee Jong Huat; Amir Ali Khan; Azim Patar; Mohammed Faruque Reza; Fauziah Mohamad Idris; Jafri Malin Abdullah; Hasnan Jaafar
Source:
Heliyon 2022 v.8 no.8 pp. e10384
ISSN:
2405-8440
Subject:
insulin-like growth factor I,   etc   ; animal injuries; animal models; cell proliferation; gene expression regulation; gene ontology; neurodevelopment; rats; stem cells; therapeutics; tissue repair;     Show all 11 Subjects
Abstract:
... Bone marrow-derived mesenchymal stem cells (BMSCs) have therapeutic potential for spinal cord injury (SCI). We have shown that insulin-like growth factor 1 (IGF-1) enhances the cellular proliferation and survivability of BMSCs-derived neural progenitor cells (NPCs) by downregulating miR-22-3p. However, the functional application of BMSCs-derived NPCs has not been investigated fully. In this study, ...
DOI:
10.1016/j.heliyon.2022.e10384

19. Mitochondrial complex IV defects induce metabolic and signaling perturbations that expose potential vulnerabilities in HCT116 cells

Author:
Oro Uchenunu; Alexander V. Zhdanov; Phillipe Hutton; Predrag Jovanovic; Ye Wang; Dmitry E. Andreev; Laura Hulea; David J. Papadopoli; Daina Avizonis; Pavel V. Baranov; Michael N. Pollak; Dmitri B. Papkovsky; Ivan Topisirovic
Source:
FEBS Open Bio 2022 v.12 no.5 pp. 959-982
ISSN:
2211-5463
Subject:
insulin-like growth factor I receptor,   etc   ; amino acids; carboxylation; colorectal neoplasms; glucose; lipids; metabolism; mitochondria; oxidation; pyruvic acid; transcription (genetics); tricarboxylic acid cycle;     Show all 12 Subjects
Abstract:
... Mutations in genes encoding cytochrome c oxidase (mitochondrial complex IV) subunits and assembly factors [e.g., synthesis of cytochrome c oxidase 2 (SCO2)] are linked to severe metabolic syndromes. Notwithstanding that SCO2 is under transcriptional control of tumor suppressor p53, the role of mitochondrial complex IV dysfunction in cancer metabolism remains obscure. Herein, we demonstrate that th ...
DOI:
10.1002/2211-5463.13398

20. The effect of IGF-1 plasma concentration on COVID-19 severity

Author:
Ebrahim Hazrati; Mohammad Gholami; Ramin Hamidi Farahani; Khodayar Ghorban; Morteza Ghayomzadeh; Negin Hosseini Rouzbahani
Source:
Microbial pathogenesis 2022 v.164 pp. 105416
ISSN:
0882-4010
Subject:
insulin-like growth factor I,   etc   ; COVID-19 infection; blood serum; death; endocrine system; gender; immune response; immune system; interleukin-6; pathogenesis; prognosis; therapeutics;     Show all 12 Subjects
Abstract:
... The severity and fatality of Coronavirus disease 2019 (COVID-19) infection are not the same in the infected population. The host immune response and Immune-stimulating factors appear to play a role in COVID-19 infection outcome. insulin-like growth factor-1 (IGF-1) affects the immune system by controlling the endocrine system. Recently, the effect of IGF-1 levels on COVID-19 prognosis has been con ...
DOI:
10.1016/j.micpath.2022.105416