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You searched for: Subject "interleukin-8" Remove constraint Subject: "interleukin-8"
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1. Establishment and characterization of a cell line from the brain of the Japanese flounder (Paralichthys olivaceus) and its application in the study of viral infection

Author:
Zhaodi Sun; Yuqin Ren; Yitong Zhang; Yucong Yang; Guixing Wang; Zhongwei He; Yufeng Liu; Wei Cao; Yufen Wang; Yuanshuai Fu; Jilun Hou
Source:
Aquaculture 2023 v.562 pp. 738825
ISSN:
0044-8486
Subject:
interleukin-8,   etc   ; Andrias davidianus; Hirame rhabdovirus; Iridovirus; Paralichthys olivaceus; actin; aquaculture; brain; cell lines; chromosome number; chromosomes; diploidy; fish; gene expression; genes; host-pathogen relationships; karyotyping; neural stem cells; temperature; transfection; viruses;     Show all 21 Subjects
Abstract:
... Fish cell lines are important tools in many biological studies. Here, we established a new Japanese flounder brain (JFB) cell line from the brain tissue of the Japanese flounder (Paralichthys olivaceus), which was successfully sub-cultured for over 120 passages, and consisted predominantly of fibroblast-like cells. Sequencing of the actin gene confirmed that JFB cells were derived from the Japanes ...
DOI:
10.1016/j.aquaculture.2022.738825

2. Effects of synthetic astaxanthin and Haematococcus pluvialis on growth, antioxidant capacity, immune response, and hepato-morphology of Oncorhynchus mykiss under cage culture with flowing freshwater

Author:
Wei Zhao; Han-Lin Wei; Meng-Die Chen; Rong Yao; Zi-Qiao Wang; Jin Niu
Source:
Aquaculture 2023 v.562 pp. 738860
ISSN:
0044-8486
Subject:
interleukin-8,   etc   ; Haematococcus pluvialis; Oncorhynchus mykiss; anti-inflammatory activity; antioxidant activity; astaxanthin; cage culture; complement; diet; fish; freshwater; growth performance; immune response; innate immunity; lipids; liver; lysozyme; muscles; necrosis; neoplasms; pigmentation; superoxide dismutase;     Show all 22 Subjects
Abstract:
... A feeding experiment was carried out to compare the effects of dietary synthetic astaxanthin and Haematococcus pluvialis on growth, antioxidant capacity, immune response and hepato-morphology of Oncorhynchus mykiss under cage culture with flowing freshwater. Three isonitrogenous and isolipidic diets were formulated with or without synthetic astaxanthin and H. pluvialis and were administered to O. ...
DOI:
10.1016/j.aquaculture.2022.738860

3. Impacts of polystyrene nanoplastics at the environmentally relevant and sub-lethal concentrations on the oxidative stress, immune responses, and gut microbiota to grass carp (Ctenopharyngodon idella)

Author:
Zhen Li; Lei Yan; Muhammad Junaid; Xikun Chen; Hongping Liao; Dandan Gao; Qiuping Wang; Yanling Zhang; Jun Wang
Source:
Journal of hazardous materials 2023 v.441 pp. 129995
ISSN:
0304-3894
Subject:
interleukin-8,   etc   ; Ctenopharyngodon idella; Proteobacteria; community structure; exposure duration; fish; freshwater; homeostasis; human health; immune response; inflammation; interleukin-10; interleukin-6; intestinal microorganisms; intestinal mucosa; microbial communities; nanoplastics; oxidative stress; pollution; polystyrenes; toxicity;     Show all 21 Subjects
Abstract:
... Nanoplastics (NPs) are emerging environmental contaminants with alarming ecological and human health concerns due to their unique physicochemical properties. This study elucidates the impacts of environmentally relevant concentrations (ERCs, 300 and 3000 ng/L) and sublethal concentrations (SLCs, 300 and 3000 μg/L) of polystyrene nanoplastics (PS-NPs, size 80 nm) on the intestinal immune response a ...
DOI:
10.1016/j.jhazmat.2022.129995

4. NMR-based metabolomic analysis for the effects of moxibustion on imiquimod-induced psoriatic mice

Author:
Feng Huang; Tong Zhang; Bin Li; Shaosong Wang; Chang Xu; Caihua Huang; Donghai Lin
Source:
Journal of ethnopharmacology 2023 v.300 pp. 115626
ISSN:
0378-8741
Subject:
interleukin-8,   etc   ; Artemisia vulgaris; Oriental traditional medicine; acupuncture; asparagine; aspartic acid; blood; cell proliferation; glucose; interleukin-17; interleukin-23; medical treatment; metabolism; metabolites; metabolomics; models; nuclear magnetic resonance spectroscopy; psoriasis; taurine; triacylglycerols; valine; wool;     Show all 22 Subjects
Abstract:
... Moxibustion is a traditional medical intervention of traditional Chinese medicine. It refers to the direct or indirect application of ignited moxa wool made of mugwort leaves to acupuncture points or other specific parts of the body for either treating or preventing diseases. Moxibustion has been proven to be effective in treating skin lesions of psoriasis. This study was performed to elucidate mo ...
DOI:
10.1016/j.jep.2022.115626

5. Seeds of Ginkgo biloba L. inhibit oxidative stress and inflammation induced by cigarette smoke in COPD rats through the Nrf2 pathway

Author:
Yiyun Qian; Liang Yan; Min Wei; Pingping Song; Lihong Wang
Source:
Journal of ethnopharmacology 2023 v.301 pp. 115758
ISSN:
0378-8741
Subject:
interleukin-8,   etc   ; Ginkgo biloba; aminophylline; animal models; antioxidants; asthma; blood serum; cigarettes; cough; enzyme-linked immunosorbent assay; glutathione peroxidase; histology; inflammation; interleukin-10; interleukin-17; interleukin-6; lipopolysaccharides; lungs; malondialdehyde; oxidative stress; smoke; superoxide dismutase; traditional medicine;     Show all 23 Subjects
Abstract:
... As a traditional medicine, seeds of Ginkgo biloba L. (Gbs) have been used to treat cough or asthma for a long time. It is commonly used in clinic for lung diseases. However, its mechanism of lung protection is not completely clear. This research was designed to explore the protective effects of Gbs on antioxidant and inflammation during the chronic obstructive pulmonary disease (COPD) pathological ...
DOI:
10.1016/j.jep.2022.115758

6. Production of NOS2 and inflammatory cytokines is reduced by selected protein kinase inhibitors with partial repolarization of HL-60 derived and human blood macrophages

Author:
Gábor Bögel; József Murányi; Bálint Szokol; Zoltán Kukor; István Móra; Tamás Kardon; László Őrfi; András Hrabák
Source:
Heliyon 2022 v.8 no.1 pp. e08670
ISSN:
2405-8440
Subject:
interleukin-8,   etc   ; blood; humans; interleukin-4; macrophages; phosphorylation;     Show all 6 Subjects
Abstract:
... JAK/STAT pathway plays a well-known role in macrophage polarization, but other signaling routes may also be involved. The aim of this study was to identify new signaling pathways and repolarize macrophages by selected protein kinase inhibitors. HL-60 derived macrophages were chosen as model cells and human blood macrophages were used for comparison. M1 and M2 polarization of HL60 derived and human ...
DOI:
10.1016/j.heliyon.2021.e08670

7. Characterization, expression and function analysis of pfTLR5S and pfTLR5M in yellow catfish (Pelteobagrus fulvidraco) responding to bacterial challenge

Author:
Gang Ouyang; Ruhan Sun; Xinyu Wan; Le Yuan; Zechao Shi; Qin Wang; Bingchao Wang; Yanzhi Luo; Wei Ji
Source:
International journal of biological macromolecules 2022 v.216 pp. 322-335
ISSN:
0141-8130
Subject:
interleukin-8,   etc   ; Tachysurus fulvidraco; gene expression; innate immunity; liver; pathogens;     Show all 6 Subjects
Abstract:
... Toll-Like Receptors (TLRs) are important pattern recognition receptors, playing critical roles in the early innate immune response to defensing against pathogen invasion. In this study, we found both soluble form TLR5 (pfTLR5S) and membrane form TLR5 (pfTLR5M) in yellow catfish Pelteobagrus fulvidraco. The open reading frames (ORFs) of pfTLR5M and pfTLR5S genes were 2655 bp and 1947 bp in length, ...
DOI:
10.1016/j.ijbiomac.2022.06.155

8. Structural insights into the activation of chemokine receptor CXCR2

Author:
Kaiwen Liu; Ling Shen; Meng Wu; Zhi‐Jie Liu; Tian Hua
Source:
FEBS journal 2022 v.289 no.2 pp. 386-393
ISSN:
1742-464X
Subject:
interleukin-8,   etc   ; antagonists; cholesterol; cryo-electron microscopy; crystal structure; neutrophils;     Show all 6 Subjects
Abstract:
... The C‐X‐C motif chemokine CXCL8 (interleukin‐8, IL‐8) and its receptor chemokine receptor 2 (CXCR2) mediate neutrophil migration during cell development and inflammatory responses and thus are related to numerous inflammatory diseases and cancers. We have determined the cryo‐electron microscopy structure of CXCL8 bound CXCR2 coupled to Gᵢ protein, as well as the crystal structure of inactive CXCR2 ...
DOI:
10.1111/febs.15865

9. Yearling bulls have reduced sperm concentration and increased seminal plasma interleukin-8 after a 28-day breeding season

Author:
Snider Alexandria P.; Mccarthy Kacie L.; Wright-Johnson Elane C.; Ondrak Jeffrey D.; Oliver William T.; Dahlen Carl R.; Cushman Robert A.; Crouse Matthew Scott
Source:
Reproduction in domestic animals 2022 v. no. pp. 1-9
ISSN:
0936-6768
Subject:
interleukin-8,   etc   ; inflammation; seminal plasma; sperm concentration; spermatogenesis; spermatozoa; yearlings;     Show all 7 Subjects
Abstract:
... We hypothesized that yearling bulls selected for a 28-d breeding season would have reduced sperm concentrations and morphology, and have increased seminal plasma concentrations of pro-inflammatory cytokine interleukin-8(IL-8). Yearling bulls were selected based on a breeding soundness examination (BSE) at approximately 415 d of age and contained at least 750 million sperm in the ejaculate, with 12 ...
Handle:
10113/7929054
DOI:
10.1111/rda.14223

10. Pharmacological effects and safety of Andrographis paniculata (Burm.f.) Nees

Author:
Jingzhuo Tian; Chunying Li; Jing Meng; Lianmei Wang; Yan Tong; Yong Zhao; Yan Yi; Yushi Zhang; Zhong Xian; Chen Pan; Suyan Liu; Jiayin Han; Aihua Liang
Source:
Journal of food science 2022 v.87 no.3 pp. 1319-1330
ISSN:
0022-1147
Subject:
interleukin-8,   etc   ; Andrographis paniculata; death; food science; intragastric administration; pharmacodynamics; rodents; therapeutics; toxicity;     Show all 9 Subjects
Abstract:
... Andrographis paniculata (Burm.f.) Nees (AP) is widely used in most Asian and some Western countries. However, its main effects and underlying pharmacological mechanism have not been thoroughly characterized, and its safety has not been sufficiently investigated. The present study aimed to predict and visualize the potential targets and pathways, clarify the main pharmacological effects, and invest ...
DOI:
10.1111/1750-3841.16079

11. Affimer sandwich probes for stable and robust lateral flow assaying

Author:
Garima Goyal; Antareep Sharma; Alfred Iing Yoong Tok; Alagappan Palaniappan; Bo Liedberg
Source:
Analytical and bioanalytical chemistry 2022 v.414 no.14 pp. 4245-4254
ISSN:
1618-2642
Subject:
interleukin-8,   etc   ; ambient temperature; analytical chemistry; biomarkers; cold storage; humans; shelf life; thermal stability;     Show all 8 Subjects
Abstract:
... Lateral flow assays (LFAs) widely deployed for on-site diagnosis have predominantly utilized antibodies as recognition molecules. Antibodies with limited thermal stability deteriorate the performance of the LFA over time. Herein, we demonstrate a stable and robust LFA by utilizing thermally stable peptide-based 12–14 kDa affimers as recognition molecules, in lieu of conventional protein-based anti ...
DOI:
10.1007/s00216-022-04078-4

12. Multiplex Cytokine Analyses in Ear Canals of Dogs Suggest Involvement of IL-8 Chemokine in Atopic Otitis and Otodectic Mange—Preliminary Results

Author:
Line-Alice Lecru; Daniel Combarros; Fabien Moog; Lukrecija Marinovic; Jevgenija Kondratjeva; Nicolas Amalric; Charline Pressanti; Marie Christine Cadiergues
Source:
Animals 2022 v.12 no.5 pp. -
ISSN:
2076-2615
Subject:
interleukin-8,   etc   ; atopic dermatitis; dogs; ears; humans; hyperplasia; interleukin-10; mange; otitis externa; pathogenesis;     Show all 10 Subjects
Abstract:
... Cutaneous cytokines and chemokines are involved in the pathogenesis of human and canine atopic dermatitis. The aim of the present study was to discriminate cytokine expression in the ear canals of atopic dogs with otitis, dogs with non-allergic inflammatory otitis (otodectic mange) and healthy non-atopic dogs. The ear canals of nine atopic dogs suffering from non-infected otitis externa (n = 14 ea ...
DOI:
10.3390/ani12050575

13. Reversible acetylation modulates p54nrb/NONO-mediated expression of the interleukin 8 gene

Author:
Jae-Eun Ryu; Taek-Yeol Jung; Seong-Hoon Park; Jun Hong Park; Hyun-Seok Kim
Source:
Biochemical and biophysical research communications 2022 v.622 pp. 50-56
ISSN:
0006-291X
Subject:
interleukin-8,   etc   ; DNA repair; acetylation; acetyltransferases; genes; lysine; methylation; phosphorylation; research; sirtuins; transcription (genetics);     Show all 11 Subjects
Abstract:
... The non-POU domain-containing octamer-binding protein (NONO, also referred to as p54nrb) is a multifunctional nuclear protein engaging in transcriptional regulation, mRNA splicing, nuclear retention of defective RNA, and DNA repair. Emerging evidence has demonstrated that p54nrb is subjected to various posttranslational modifications, including phosphorylation and methylation, which may be importa ...
DOI:
10.1016/j.bbrc.2022.06.085

14. Visualization of Marek’s Disease Virus Genomes in Living Cells during Lytic Replication and Latency

Author:
Tereza Vychodil; Darren J. Wight; Mariana Nascimento; Fabian Jolmes; Thomas Korte; Andreas Herrmann; Benedikt B. Kaufer
Source:
Viruses 2022 v.14 no.2 pp. -
ISSN:
1999-4915
Subject:
interleukin-8,   etc   ; DNA; fish; fluorescence; giant cells; hybridization; tetracycline; viral genome; virus replication; viruses;     Show all 10 Subjects
Abstract:
... Visualization of the herpesvirus genomes during lytic replication and latency is mainly achieved by fluorescence in situ hybridization (FISH). Unfortunately, this technique cannot be used for the real-time detection of viral genome in living cells. To facilitate the visualization of the Marek’s disease virus (MDV) genome during all stages of the virus lifecycle, we took advantage of the well-estab ...
DOI:
10.3390/v14020287

15. Central and peripheral effects of L-citrulline on thermal physiology and nitric oxide regeneration in broilers

Author:
Victoria Anthony Uyanga; Lei Liu; Jingpeng Zhao; Xiaojuan Wang; Hongchao Jiao; Hai Lin
Source:
Poultry science 2022 v.101 no.3 pp. 101669
ISSN:
0032-5791
Subject:
interleukin-8,   etc   ; citrulline; dose response; gene expression; hypothalamus; hypothermia; interleukin-10; neurons; nitric oxide; ultrastructure;     Show all 10 Subjects
Abstract:
... The mechanism that mediates L-citrulline (L-Cit) hypothermia is poorly understood, and the involvement of nitric oxide signaling has not been fully elucidated. Therefore, this study aimed to determine L-Cit's influence on body temperature and to ascertain the central and peripheral mechanisms associated with this response. Chicks responded to intracerebroventricular (ICV) injection of L-Cit with h ...
DOI:
10.1016/j.psj.2021.101669

16. A healthier daily diet is associated with greater immune fitness

Author:
Evi C. van Oostrom; Kiki EW Mulder; Marjolijn CE Verheul; Pauline A. Hendriksen; Suzan Thijssen; Aletta D. Kraneveld; Berber Vlieg-Boerstra; Johan Garssen; Joris C. Verster
Source:
PharmaNutrition 2022 v.21 pp. 100306
ISSN:
2213-4344
Subject:
interleukin-8,   etc   ; C-reactive protein; biomarkers; cross-sectional studies; healthy diet; immune system; questionnaires; saliva;     Show all 8 Subjects
Abstract:
... The aim of this cross-sectional study was to investigate the association between a healthier diet, perceived immune fitness, and biomarkers of the immune system. N = 108 participants (31 men and 77 women), 18–30 years old, completed a questionnaire, comprising the Healthy Diet Scale (HDS) and a 1-item scale assessing perceived immune fitness. In addition, saliva samples were collected and C-reacti ...
DOI:
10.1016/j.phanu.2022.100306

17. Cortisol inhibits lipopolysaccharide-induced inflammatory response in bovine endometrial stromal cells via NF-κB and MAPK signaling pathways

Author:
Li Fang; Luying Cui; Kangjun Liu; Xinyu Shao; Wenye Sun; Jun Li; Heng Wang; Chen Qian; Jianji Li; Junsheng Dong
Source:
Developmental and comparative immunology 2022 v.133 pp. 104426
ISSN:
0145-305X
Subject:
interleukin-8,   etc   ; Escherichia coli; Western blotting; cortisol; endometrium; fluorescent antibody technique; inflammation; interleukin-6; lipopolysaccharides; phosphorylation;     Show all 10 Subjects
Abstract:
... Bovine uterine infection is commonly caused by Escherichia coli (E. coli). Elevated concentrations of plasma cortisol have been reported in postpartum cows. However, the direct role of cortisol in the inflammatory response of bovine endometrial stromal cells (BESCs) remains unclear. Therefore, the aim of the study was to explore the regulatory effect of cortisol on lipopolysaccharide (LPS)-induced ...
DOI:
10.1016/j.dci.2022.104426

18. Finding a cell-permeable compound to inhibit inflammatory cytokines: Uptake, biotransformation, and anti-cytokine activity of javamide-I/-II esters

Author:
Jae B. Park
Source:
Life sciences 2022 v.291 pp. 120280
ISSN:
0024-3205
Subject:
interleukin-8,   etc   ; Western blotting; biotransformation; caffeic acid; inflammation; interleukin-1beta; phosphorylation; tryptophan; tumor necrosis factor-alpha;     Show all 9 Subjects
Abstract:
... Currently, there is limited information available about cell-permeability and anti-cytokine activity of javamide-I/-II esters in monocyte/macrophage-like cells. Therefore, the aim of this study was to investigate their cell-permeability and anti-cytokine activity in the cells. The uptake of javamide-I/-II and esters was studied in THP-1 cells and PBMCs. Also, kinetic and inhibition studies were co ...
DOI:
10.1016/j.lfs.2021.120280
CHORUS:
10.1016/j.lfs.2021.120280

19. Inhibitory effect of Buddlejasaponin IVb on porcine epidemic diarrhea virus in vivo and in vitro

Author:
Pei Sun; Mingge Wang; Jie Li; Yanping Qiu; Hongyue Li; Muze Lv; Zongyi Bo; Haixiao Shen; Liang Li
Source:
Veterinary microbiology 2022 v.272 pp. 109516
ISSN:
0378-1135
Subject:
interleukin-8,   etc   ; Porcine epidemic diarrhea virus; apoptosis; diarrhea; dose response; industry; interleukin-6; intestines; microbiology; therapeutics;     Show all 10 Subjects
Abstract:
... Porcine epidemic diarrhea virus (PEDV) is one of the main pathogens causing severe diarrhea in piglets. Infection of the host induces apoptosis, causing huge economic losses to the pig industry. At present, the preventive and therapeutic effects of commercial vaccines are not satisfactory, and it is necessary to develop new anti-PEDV drugs. In this study, we screened the PEDV-inhibiting drug Buddl ...
DOI:
10.1016/j.vetmic.2022.109516

20. Effects of QingYi decoction on inflammatory markers in patients with acute pancreatitis: A meta-analysis

Author:
Guanyu Wang; Dong Shang; Guixin Zhang; Shenglin Zhang; Nan Jiang; Huanhuan Liu; Hailong Chen
Source:
Phytomedicine 2022 v.95 pp. 153738
ISSN:
0944-7113
Subject:
interleukin-8,   etc   ; chi-square distribution; interleukin-10; interleukin-6; meta-analysis; pancreatitis; risk; systematic review; therapeutics;     Show all 9 Subjects
Abstract:
... It is widely accepted that inflammatory responses play a key role in acute pancreatitis (AP). We conducted a systematic review and meta-analysis to determine the effect of QingYi decoction on inflammatory markers.The PubMed, EMBASE, Cochrane, CNKI, CBM, and WANFGANG databases were searched for randomized controlled trials published before December 2019. Thirty-nine eligible studies were included i ...
DOI:
10.1016/j.phymed.2021.153738