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... Arsenic can be specifically enriched by rice, and the health hazards caused by high arsenic rice are gradually attracting attention. This study aimed to explore the potential of microbial detoxification via gut microbiome in the treatment of sub-chronic arsenic poisoning. We first exposed mice to high-dose arsenic feed (30 mg/kg, rice arsenic composition) for 60 days to promote arsenic-induced mic ...
... Cyprinid herpesvirus 2 (CyHV-2) is a highly contagious pathogen that causes herpesviral haematopoietic necrosis (HVHN) disease to goldfish, Carassius auratus and gibel carp, C. auratus gibelio. In this study, the virus persistence or latency in apparently healthy farmed gibel carp and reactivation in vitro were investigated. All of the freshly dissected kidney tissues of 42 individuals of asymptom ...
kidneys, etc ; DNA; cobalt; detection limit; electrochemistry; electrodes; enzyme-linked immunosorbent assay; food chemistry; human health; ochratoxin A; oligonucleotides; red wines; toluidine blue; Show all 13 Subjects
Abstract:
... Ochratoxin A (OTA) is a naturally occurring mycotoxin that poses serious threats, such as kidney damage, to human health. Therefore, we developed a DNA walker-based dual-signal electrochemical ratiometric platform for OTA detection, which could overlook the variations in environmental and instrumental factors and DNA load densities. Cobalt metal–organic frameworks (Co-MOFs) and toluidine blue were ...
... The improvement of disease resistance is vital in aquaculture as diseases are one of the serious threats to successful aquaculture. Understanding of molecular mechanisms underlying disease resistance is important in improving resistance against diseases. The pIgR (polymeric immunoglobulin receptor) gene plays an important role in the mucosal immunity of fish. However, not much is known about its r ...
... Pseudomonas plecoglossicida is an important pathogenic bacterial species in aquaculture, causing visceral granulomas in large yellow croaker (Larimichthys crocea) and several other economically important fish species. The GacS/GacA is a two-component regulatory system (TCS) primarily found in Pseudomonads for its role in virulence, quorum sensing, and biofilm formation. To investigate the potentia ...
... The binding of flagellin to receptor TLR5 (Toll-like receptor 5) on the cell surface is a prerequisite for the pathogen infection to the body, which has important implication for disease prevention. Unlike mammals, teleost TLR5 exists in two different forms: membrane-bound TLR5M (membrane TLR5, TLR5M) and secreted TLR5S (soluble TLR5, TLR5S). In this study, TLR5M and TLR5S from Nile tilapia (Oreoc ...
... Allied to the problem of gastrointestinal parasites, especially Haemochus contortus, the use of lectins of plant origin has contributed to the research of alternative anthelmintics. The nematicidal effect of a water soluble Moringa oleifera lectin (WSMoL) was investigated in an experimental model with H. contortus infected Wistar rodents. Three concentrations were tested orally: 5 mg/kg, 2.5 mg/kg ...
... Viral hemorrhagic septicemia (VHS) in olive flounder (Paralichthys olivaceus) causes considerable economic losses in the flounder aquaculture industry in Korea. This study was aimed to identify the immune-associated genes contributing to VHSV infection progression in the kidneys of the olive flounder. Ten fish were divided into two groups via an intraperitoneal injection with either diethylpyrocar ...
kidneys, etc ; Oncorhynchus mykiss; data collection; depuration; detection limit; diet; dietary exposure; environment; excretion; fish; fish health; food chain transfer; gall bladder; ingestion; intestines; liver; mass spectrometry; nanoplastics; polystyrenes; Show all 19 Subjects
Abstract:
... The ingestion of nanoplastics (NPs) by fish has led to concerns regarding fish health and food chain transfer, but analytical constraints have hindered quantitative data collection on their uptake and depuration. We used palladium-doped polystyrene nanoplastics (PS-Pd NPs, ~200 nm) to track particle fate in rainbow trout (Oncorhynchus mykiss) during a week-long dietary exposure and subsequent 7-da ...
... Major histocompatibility complex (MHC) molecules play a critical role in the immune response of vertebrate animals by presenting foreign antigens to T lymphocytes. In this study, we first cloned and identified a classical and a novel nonclassical MHC I α molecules from Japanese eel (Anguilla japonica), named as AjMHC I-UBA and AjMHC I-L, respectively. The full-length cDNA of AjMHC I-UBA contains a ...
... Wood burning is a major source of ambient particulate matter (PM) and has been epidemiologically linked to adverse pulmonary health effects, however the impact of fuel and burning conditions on PM properties has not been investigated systematically. Here, we employed our recently developed integrated methodology to characterize the physicochemical and biological properties of emitted PM as a funct ...
... Pomegranate peel extract (PPE) has been widely identified as a rich source of therapeutically active phyto-compounds, known for their beneficial effects in aquaculturable species. In this context, a 60-day feeding trial was carried out to evaluate the effect of supplementation of pomegranate peel extract (PPE) on growth performance, haemato-immunological responses and cytokine gene expression in L ...
kidneys, etc ; Cyprinus carpio; absorption; aquaculture; bile; body weight; carp; confidence interval; danofloxacin; drugs; freshwater; half life; high performance liquid chromatography; intestines; liver; maximum residue limits; models; muscles; oral administration; pharmacokinetics; Yellow River; Show all 21 Subjects
Abstract:
... The current research aimed to explore the residue depletion of danofloxacin in Yellow River carp (Cyprinus carpio haematopterus) reared in fresh water at 17.8 ± 0.7 °C after oral administration at 10 mg/kg body weight (BW) daily for five consecutive days. Different samples, including plasma, bile, skin-on muscle, liver, kidney, gill, and intestine, were collected at 1, 4, 8, 12 h, 1, 2, 3, 5, 7, 1 ...
kidneys, etc ; Aconitum carmichaelii; Aconitum kusnezoffii; Delphinium; Oriental traditional medicine; absorption; analgesics; antioxidants; brain; digestive tract; diterpenoids; drug development; feces; heart; heart diseases; liver; liver microsomes; nervous system diseases; pharmacodynamics; pharmacokinetics; statistics; toxicity; urine; Show all 23 Subjects
Abstract:
... Aconitum medicinal materials, such as Aconitum carmichaelii Debeaux (Chinese: Wutou/乌头) and Aconitum kusnezoffii Reichb. (Chinese: Caowu/草乌), are a kind of important Traditional Chinese Medicine (TCM) with great medicinal value. Statistics show that there are over 600 efficient TCM formulations comprising Aconitum medicinal materials. But high toxicity limits their clinical application. Clinically ...
... Climate change leads to an increase in water acidification and temperature, two environmental factors that can change fish appetite and metabolism, affecting fish population in both wild and aquaculture facilities. Therefore, our study tested if climate change affects gene expression levels of two appetite-regulating peptides – Neuropeptide Y (NPY) and Cholecystokinin (CCK) – in the brain of tamba ...
... Nucleic acid hybridization is occurred between the selective single-stranded nucleic acid sequence and its target sequence, which is one of the essential procedure for electrochemical detection of nucleic acid. microRNA-21 (miRNA-21) is known as a biomarker in various cancers. The determination of miRNA-21 was attained through by hybridization of inosine substituted miRNA-21 specific DNA probe (Pᵢ ...
kidneys, etc ; Atractylodes lancea; Magnolia officinalis; Oriental traditional medicine; Western blotting; adiponectin receptors; agonists; animal models; diet; fluorescent antibody technique; fructose; humans; insulin; insulin resistance; liquid chromatography; non-specific serine/threonine protein kinase; pharmacology; rats; tandem mass spectrometry; therapeutics; thermosensitivity; Show all 21 Subjects
Abstract:
... In traditional Chinese medicine, a long term of improper diet causes the Dampness and disturbs Zang-Fu's functions including Kidney deficiency. Atractylodes lancea (Atr) and Magnolia officinalis (Mag) as a famous herb pair are commonly used to transform Dampness, with kidney protection. To explore how Atr and Mag protected against insulin signaling impairment in glomerular podocytes induced by hig ...
... Global interest in phytogenic feed additives as alternatives to antibiotics in feed has been spurred by the banning of antibiotic growth promoters by several countries. Suitable plant extracts for development of phytogenic feed additives should have therapeutic value and should also be safe. The aim of this study was to evaluate the antibacterial, antioxidant and anti-lipoxygenase activities as we ...
... Triclosan (TCS) is a ubiquitous antimicrobial used in daily consumer products. Previous reports have shown that TCS could induce hepatotoxicity, endocrine disruption, disturbance on immune function and impaired thyroid function. Kidney is critical in the elimination of toxins, while the effects of TCS on kidney have not yet been well-characterized. The aim of the present study was to investigate t ...
... Peganum harmala L. is a traditional medicinal plant used for centuries in folk medicine. It has a wide array of therapeutic attributes, which include hypoglycemic, sedative, anti-inflammatory, and antioxidant properties. The fruit decoction of this plant was claimed by Avicenna as traditional therapy for urolithiasis. Also, P. harmala seed showed a clinical reduction in kidney stone number and siz ...