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lactose, etc ; active pharmaceutical ingredients; aspirin; cellulose; hardness; lignin; milling; sieving; Show all 8 Subjects
Abstract:
... The main focus of this paper is on the improvement of formulations utilising non-conventional bio-based excipients to improve tablet release rates. Two different formulations were considered. The first formulation contains Alcell lignin, lactose monohydrate and microcrystalline cellulose as excipients and acetylsalicylic acid (aspirin) as active pharmaceutical ingredient (API). The second formulat ...
lactose, etc ; biochemical pathways; electric field; fructose; honors and awards; transmittance; Show all 6 Subjects
Abstract:
... Special recognition to molecules is essential for many biochemical processes, thus highly sensitive sensing methods for molecule recognition are strongly demanded. Recently, metamaterials present a unique platform for sensing applications owing to their exotic properties. In the current work, a metamaterial sensor for enhanced fingerprint detection of lactose based on resonant coupling of plasmoni ...
lactose, etc ; cellulose; compressibility; granules; lignin; manufacturing; milling; powders; Show all 8 Subjects
Abstract:
... In this study, a process map was developed in an effort to improve the understanding of dry granulation of pharmaceutical excipients by roll compaction process, and to implement the quality-by-design (QbD) approach. Through development of the process map, a correlation was made between the critical process parameters (roll pressure, screw speed), and critical quality attributes (density of ribbons ...
lactose, etc ; air; ambient temperature; dialysis; foams; freeze drying; liquids; monitoring; pH; water activity; whey protein isolate; Show all 11 Subjects
Abstract:
... In the present work, we investigated the effects of powder dry-heating parameters on whey protein foams stability, especially against drainage.To this aim, whey protein isolate solutions were prepared at various pH (3.5, 5.0, 6.5), with or without a prior dialysis step to reduce the lactose content, freeze-dried, adjusted to various levels (0.12, 0.23, 0.52) of powder water activity aw and dry-hea ...
lactose, etc ; Fourier transform infrared spectroscopy; beta-galactosidase; encapsulation; enzyme activity; hydrolysis; lysozyme; silica; skim milk; Show all 9 Subjects
Abstract:
... In this study, an amino-functionalized silica matrix encapsulating β-galactosidase was first synthesized in situ, with subsequent covalent anchoring of lysozyme to the outer part of the amino-grafted matrix. Fourier transform infrared (FTIR) spectra verified that β-galactosidase was successfully encapsulated. Meanwhile, the co-immobilized enzymes were demonstrated to retain suitable enzymatic acti ...
... Lactose hydrolyzed milk was developed in the 1970s to serve individuals with lactose intolerance. This demand for lactose-free products by lactose-intolerant consumers has created a market segment for this food whose quality control has to be guaranteed. In order to assess milk samples for lactose content, this work proposes an analytical methodology to classify regular and lactose-free ultra high ...
lactose, etc ; dielectric properties; skim milk; whole milk; Show all 4 Subjects
Abstract:
... Dielectric properties (dielectric constant ε′ and dielectric loss factor ε′′) of whole milk and skim milk with the lactose content of 4.56–6.44% and 4.57–6.47%, respectively, were measured over the frequency range of 20–4500 MHz at 25 °C using a vector network analyzer. The results showed that ε′ decreased with increasing frequency, and ε′′ changed with V shape and its minimum was noted at about 2 ...
... Secondary nucleation is the dominant source of nuclei at the industrial scale. Traditionally, secondary nucleation has been expressed empirically as a function of stirrer speed and magma density with little or no understanding about the role of individual mechanisms (attrition and contact). This study considers the various mechanisms of secondary nucleation of alpha-lactose monohydrate crystals an ...
lactose, etc ; Escherichia coli; Thermotoga; anion exchange; beta-glucuronidase; glycosides; heat; hydrophobic interaction chromatography; pH; polyacrylamide gel electrophoresis; temperature; thermal stability; Show all 12 Subjects
Abstract:
... A multimodular hyperthermophilic β‑glucuronidase (TpGUS) from Thermotoga petrophila RKU-1T, belongs to glycoside hydrolase family 2 (GH2), was cloned and overexpressed in Escherichia coli BL21 CodonPlus (DE3)-RIPL. Expression and production of extracellular TpGUS was enhanced through various specific cultivation and induction strategies. Extracellular TpGUS activity was improved by 3.44 and 7 fold ...
lactose, etc ; Maillard reaction; color; crosslinking; heat; hydrocolloids; microparticles; pH; powders; protein denaturation; water activity; water content; whey protein isolate; Show all 13 Subjects
Abstract:
... Dry heating (DH) at 100 °C of a whey protein isolate powder conditioned at pH 9.5 leads to the formation of stable, large and porous whey protein microparticles (WPM), resulting from crosslinking of proteins in the powder. The Maillard reaction (MR) is probably involved in the formation of these WPM. To confirm the role played by the MR and understand the protein changes occurring during particle ...
lactose, etc ; antioxidant activity; calcium chloride; electric current; electrical resistance; fouling; isomerization; lactulose; magnesium chloride; potassium chloride; scanning electron microscopy; whey; Show all 12 Subjects
Abstract:
... Whey permeate (WP) was valorised through in situ isomerisation of lactose into lactulose by electro-activation. The effect of electric current intensity and salt (CaCl2, KCl and MgCl2) on the amount of lactose conversion into lactulose using WP (6%, w/w) and pure lactose (5%, w/w) solutions was studied. Lactose was converted into lactulose at a level of 35.1% when KCl at current intensity of 330 m ...
lactose; lactose intolerance, etc ; UHT milk; chromatography; formates; lactulose; milk; Show all 7 Subjects
Abstract:
... Lactose intolerance is the decreased ability to digest lactose, and the population involved is rapidly increasing all over the world. Different procedures have been reported in the literature to quantify lactose in dairy products, but the official method of analysis is based on enzymatic assay. In this paper, the effectiveness of two enzymatic kits in detecting residual lactose in lactose-free mil ...
... Usage of forward osmosis membrane in FO mode, in which active and support layers of the membrane were in contact with the feed and the draw solutions respectively, provided higher initial water flux (12L/m2h) than the usage of membrane in PRO mode (6L/m2h) having opposite orientation but fluxes approached to each other after 4h during concentration of whey with NH3/CO2 as draw salt. High organic a ...
... There is no consensus on the most accurate method to diagnose primary hypolactasia. We aimed to compare the diagnostic accuracy of the new gaxilose test with 2 traditional tests (lactose tolerance test and clinical criteria) for the diagnosis of primary hypolactasia using the C/T-13910 polymorphism as a reference standard.Patients with a clinical suspicion of lactose intolerance were subjected to ...
lactose, etc ; Aspergillus oryzae; beta-galactosidase; biocatalysts; galactooligosaccharides; hydrolysis; particle size; Show all 7 Subjects
Abstract:
... The simultaneous reactions of lactose hydrolysis and transgalactosylation in the production of galacto-oligosaccharides (GOS) were evaluated with immobilized Aspergillus oryzae β-galactosidase in glyoxyl-agarose of different particle sizes (fine and macro) and enzyme loads (1, 10 and 30 mgprotein/gsupport) to produce biocatalysts subjected to different magnitudes of internal diffusional restrictio ...
lactose, etc ; aqueous solutions; freeze drying; mannitol; porosity; sublimation; temperature; Show all 7 Subjects
Abstract:
... The lyophilization of lactose and mannitol aqueous solutions was investigated with an emphasis on analyzing the effects of controlled nucleation, temperature of nucleation, and pore size distribution on the freeze-drying process. The experimental procedure involved the depressurization technique of controlled nucleation, in-vial temperature measurements as well as measurements of the chamber press ...
lactose, etc ; cheesemaking; gels; manufacturing; milk; minerals; mozzarella cheese; proteins; Show all 8 Subjects
Abstract:
... From its journey from milk through to its end use, Mozzarella cheese undergoes significant transformations in its makeup of components and their structural arrangement. The typical Mozzarella processing steps each alter the structural configuration of the system. The colloidal dispersion of proteins, fat, lactose and minerals that is milk experiences physical, thermal, chemical, biological and ion ...
lactose, etc ; Addax nasomaculatus; colostrum; cows; goats; milk; sheep; Show all 7 Subjects
Abstract:
... Mammalian milk/colostrum usually contains milk oligosaccharides along with the predominant lactose. Although milk oligosaccharides of a variety of Bovidae species including cow, sheep and goat have been characterized, those of the addax, an Antelopinae species of the Bovidae, have not as yet been clarified. In this study, several sialyl oligosaccharides were purified from a sample of addax colostr ...
lactose; lactose free diet, etc ; air temperature; concentrated milk; dried milk; drying; galactose; glucose; industrialization; powders; stickiness; thermodynamics; Show all 12 Subjects
Abstract:
... Industrial production of lactose hydrolyzed milk powder (LHMP) remains challenging. Due to the presence of the monosaccharides glucose and galactose, lactose-free powders tend to suffer stickiness, caking, and browning during drying and storage. We sought to find ideal conditions spray dryer inlet air temperature (θₐᵢᵣ,ᵢₙ) and concentrated milk flow rate (mCM) for LHMP production. We tested θₐᵢᵣ,ᵢ ...
... A novel low pH fermentation process was studied for the conversion of lactose using Lactobacillus plantarum and Lactobacillus buchneri under anoxic conditions in single co-culture, and two-stage sequential fermentations. This is aimed at producing acetate and propylene glycol (PG) as environmentally benign substitutes for currently used road and aircraft deicing chemicals. The results indicate tha ...