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lycopene, etc ; Escherichia coli; Osmanthus fragrans; biosynthesis; cultivars; flavor; Show all 6 Subjects
Abstract:
... Sweet osmanthus (Osmanthus fragrans) flowers, as a food flavor additive, are rich in carotenoids, the majority of which are cyclized carotenoids. Lycopene β- and ε-cyclases (LCYB and LCYE, respectively) catalyze the cyclization of the open ends of acyclic lycopene and manipulate the metabolic flux into different downstream branches. Although both LCYB and LCYE have been fully characterized in many ...
lycopene, etc ; Momordica charantia; formic acid; grapefruits; horticulture; temperature; Show all 6 Subjects
Abstract:
... A quick, simple, and reliable isocratic ultra-performance supercritical fluid chromatography-photodiode array detector (UPSFC-DAD) method was developed and validated to determine lycopene in different horticultural products. The effects of stationary phase, co-solvent, pressure, temperature, flow rate, and mobile phase additive on the separation of lycopene were evaluated. The developed method inv ...
lycopene, etc ; Raman spectroscopy; absorption; astaxanthin; lutein; transmission electron microscopy; Show all 6 Subjects
Abstract:
... Tuning the conformations of flexible molecules has recently shown promise as a strategy for creating new materials. However, the creation of soft-molecule materials remains challenging because these materials are typically characterized without fully considering the contribution of molecular distortion. Carotenoids are flexible, polyene-based molecules that are prone to molecular distortion, which ...
Adriany das Graças Nascimento Amorim; Andreanne Gomes Vasconcelos; Jessica Souza; Ana Oliveira; Beatriz Gullón; José Roberto de Souza de Almeida Leite; Manuela Pintado
lycopene, etc ; antioxidants; bioavailability; biosynthesis; cytotoxicity; encapsulation; fluorescence; humans; isomers; permeability; Show all 10 Subjects
Abstract:
... The purpose of this review was to collect relevant chemical data about lycopene and its isomers, which can be extracted using different non-polar or polar aprotic solvents by SC-CO₂ or biosynthesis as a friendly technique. Lycopene and other carotenoids can be identified and quantified by UV–Vis and HPLC using a C18 or C30 column, while their characterization is possible by UV–Vis, Fluorescence, F ...
lycopene, etc ; activation energy; catalysts; catalytic activity; cis-trans isomers; isomerization; Show all 6 Subjects
Abstract:
... In this paper, the effects of eleven metal salts on the isomerization and stability of lycopene were screened. The results showed that AlCl₃, Al₂(SO₄)₃, FeCl₃, Fe₂(SO₄)₃, and CuSO₄ had significant catalytic effects (p < 0.05) on lycopene isomerization. The total content of lycopene Z-isomers were in the order of FeCl₃ (70.8%) > Fe₂(SO₄)₃ (54.0%) > AlCl₃ (50.2%) > CuSO₄ (40.0%) > Al₂(SO₄)₃ (29.3%) ...
lycopene, etc ; agricultural industry; atrazine; bioactive compounds; inflammasomes; oxidative stress; pyroptosis; spleen; Show all 8 Subjects
Abstract:
... Nlrp3 is a vital integration point of diverse extracellular stimuli and cellular stress. However, the inappropriate activation of Nlrp3 results in the progression of autoinflammatory and metabolic disorders. Atrazine, which is used widely in the agricultural sector, is toxic to humans. Herein, this study found that atrazine could induce oxidative stress and the expression of Nfkb and IRF1 in splee ...
lycopene, etc ; Escherichia coli; biomass; carbon metabolism; cell growth; enzymes; food chemistry; Show all 7 Subjects
Abstract:
... Engineering microbes to produce isoprenoids can be limited by the competition between product formation and cell growth because biomass and isoprenoids are naturally derived from central metabolism. Recently, a two-step synthetic pathway was developed to partially decouple isoprenoid formation from central carbon metabolism. The pathway used exogenously added isopentenols as substrates. In the pre ...
lycopene, etc ; abscisic acid; biosynthesis; chloroplasts; chromoplasts; mutants; phytoene synthase; tomatoes; triethylamine; Show all 9 Subjects
Abstract:
... In ripening tomato fruits, the leaf-specific carotenoids biosynthesis mediated by phytoene synthase 2 (PSY2) is replaced by a fruit-specific pathway by the expression of two chromoplast-specific genes: phytoene synthase 1 (PSY1) and lycopene-β-cyclase (CYCB). Though both PSY1 and PSY2 genes express in tomato fruits, the functional role of PSY2 is not known. To decipher whether PSY2-mediated carote ...
lycopene, etc ; astaxanthin; bioavailability; cognition; eyes; human health; lutein; metabolism; microorganisms; vision; Show all 10 Subjects
Abstract:
... Carotenoids have been the object of numerous observational, pre-clinical and interventional studies focused on elucidating their potential impacts on human health. However, the large heterogeneity among the trials, in terms of study duration and characteristics of participants, makes any conclusion difficult to draw. The present study aimed to explore the current carotenoid research trends by anal ...
lycopene, etc ; drug therapy; hyperplasia; medicine; prostatitis; rats; urinary tract; urolithiasis; vitamin A; Show all 9 Subjects
Abstract:
... Benign prostatic hyperplasia, urolithiasis, recurrent urinary tract infections, and chronic prostatitis are diseases that are commonly diagnosed worldwide. Carotenoids, including lycopene, are widely available in fruits and vegetables, and it is postulated that they can be used in the prevention and treatment of benign urological conditions. The aim of this review is to familiarize doctors and the ...
lycopene, etc ; DNA methylation; ascorbic acid; color; ethylene; fruits; genomic islands; melatonin; tomatoes; Show all 9 Subjects
Abstract:
... Melatonin (MT) as an evolutionarily highly conserved molecule plays an exceptional role in plants. In the present study, the regulation mechanism of the DNA methylation of CpG islands of ethylene signaling genes induced by MT on postharvest ripening of tomato fruit was studied. The ripening of tomato fruit was significantly promoted by the 0.5 mM MT treatment, as revealed by the appearance color, ...
lycopene, etc ; ascorbic acid; bioactive compounds; energy; food science; temperature; tomato juice; ultrasonics; Show all 8 Subjects
Abstract:
... We investigated the simultaneous effects of temperature, ultrasound, and vacuum pressure in the tomato juice concentration process. To this end, a novel ultrasound-thermal concentrator under vacuum conditions was fabricated. The process was performed at three levels of ultrasound power (48, 84, and 120 W), three vacuum pressures (10, 20, and 30 kPa), and three temperatures (50, 60, and 70 °C). Als ...
lycopene, etc ; Saccharomyces cerevisiae; biochemical pathways; biosynthesis; biotechnology; gene order; genes; manufacturing; transcription (genetics); Show all 9 Subjects
Abstract:
... Metabolic engineering of microbial cell factories through integrating the heterologous synthetic pathway into the chromosome is most commonly used for industrial applications. However, the position of the foreign gene in the chromosome can affect its transcriptional level. As a microorganism that is generally regarded as safe (GRAS) and commonly applied in industrial manufacture with large-scale o ...
lycopene, etc ; Lewis acids; Lewis bases; dietary supplements; food chemistry; homeostasis; lipophilicity; oxidation; phytochemicals; tomatoes; Show all 10 Subjects
Abstract:
... Phytochemical electrophiles are drawing significant attention due to their properties to modulate signaling pathways related to cellular homeostasis. The aim of this study was to develop new tools to examine the electrophilic activity in food and predict their beneficial effects on health. We developed a spectrophotometric assay based on the nitrobenzenethiol (NBT) reactivity, as a thiol-reactive ...
lycopene, etc ; Nicotiana tabacum; Rhododendron; amino acid sequences; biosynthesis; color; flower color; flowering; genes; tobacco; Show all 10 Subjects
Abstract:
... Rhododendron molle G. Don is a deciduous species of Rhododendron with unique yellow flowers. Carotenoids play a major role in flower coloration. Lycopene β-cyclase (LCYB) is an essential enzyme which catalyzes the synthesis of β-carotene from lycopene in the carotenoid biosynthesis pathway. However, the molecular function of the LCYB gene in R. molle remains unknown. In this study, the RmLCYB gene ...
Haiyan Luo; Zhengze Li; Chad R. Straight; Qi Wang; Jiazhi Zhou; Yukun Sun; Chia-yu Lo; Lingxiao Yi; Yanyan Wu; Jingyuan Huang; William Wolfe; Dianne Z. Sutherland; Mark S. Miller; David Julian McClements; Eric A. Decker; Hang Xiao
lycopene, etc ; bioavailability; black pepper; canola; canola oil; cross-over studies; emulsions; food chemistry; lutein; salads; vegetables; Show all 11 Subjects
Abstract:
... This study demonstrated the combination of black pepper and a canola oil-based emulsion synergistically enhanced carotenoid bioavailability of raw vegetables in humans. In a randomized crossover design, healthy young adults consumed (1) vegetable salad (control), (2) salad with canola oil emulsion (COE), (3) salad with black pepper (BP), and (4) salad with canola oil emulsion and black pepper (COE ...
lycopene, etc ; Escherichia coli; bacterial culture; genetic transformation; high performance liquid chromatography; lactose; milk; phenotype; plasmids; spectrophotometers; Show all 10 Subjects
Abstract:
... Lycopene is an orange–red carotenoid, which confers a visual phenotype to assess genetic transformation of microorganisms. In this study, the lycopene synthesis pathway was constructed in engineered Escherichia coli BL21 (DE3) by transforming plasmid pET-15b-crtBEI, wherein crtB, crtE, and crtI could be expressed under the control of the T7 promoter and lacO operator and lycopene could be accumula ...
... Cardiovascular diseases rank first in mortality worldwide. Platelets have been considered the main cardiovascular risk factor since they play an important role, in atherosclerosis and the development of acute thrombotic events. The hyperactivation of platelets leads to platelet aggregation and the formation of clogs, blocking the passage of blood to the different organs and tissues. Blood obstruct ...
... Nano-encapsulation is promising in improving the stability and biological activity of bioactive compounds. Here, the food-sourced protein nanotubes (NTs) from self-assembly of partially hydrolyzed α-lactalbumin (α-lac) were developed. The α-lac NTs had a dimension of 20 nm in diameter and 200–1000 nm in length. Lycopene (LYC) was loaded into the hydrophobic inner wall of NTs via hydrophobic intera ...
lycopene, etc ; Myxococcus xanthus; Raman imaging; analytical chemistry; heat; nutrient availability; principal component analysis; secondary metabolites; soil bacteria; Show all 9 Subjects
Abstract:
... Myxococcus xanthus is a common soil bacterium with a complex life cycle, which is known for production of secondary metabolites. However, little is known about the effects of nutrient availability on M. xanthus metabolite production. In this study, we utilize confocal Raman microscopy (CRM) to examine the spatiotemporal distribution of chemical signatures secreted by M. xanthus and their response ...