U.S. flag

An official website of the United States government

Dot gov

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Https

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

PubAg

Main content area

You searched for: Subject "lycopene" Remove constraint Subject: "lycopene"
Start Over

Search

3,203  Search Results

« Previous | 1 - 20 of 3,203 |
Number of results to display per page

Search Results

1. Functional Characterization of Two Lycopene Cyclases from Sweet Osmanthus (Osmanthus fragrans)

Author:
Hongsheng Qing; Jiahong Chen; Lingli Jiang; Jieyu Qian; Jianxin Fu; Chao Zhang
Source:
Scientia horticulturae 2022 v.299 pp. 111062
ISSN:
0304-4238
Subject:
lycopene,   etc   ; Escherichia coli; Osmanthus fragrans; biosynthesis; cultivars; flavor;     Show all 6 Subjects
Abstract:
... Sweet osmanthus (Osmanthus fragrans) flowers, as a food flavor additive, are rich in carotenoids, the majority of which are cyclized carotenoids. Lycopene β- and ε-cyclases (LCYB and LCYE, respectively) catalyze the cyclization of the open ends of acyclic lycopene and manipulate the metabolic flux into different downstream branches. Although both LCYB and LCYE have been fully characterized in many ...
DOI:
10.1016/j.scienta.2022.111062

2. Process Development for the Instant Quantification of Lycopene from Agricultural Produces Using Supercritical Fluid Chromatography-Diode Array Detector (SFC-DAD)

Author:
Supriya Priyadarsani; Avinash Singh Patel; Yogesh Sharma; Abhijit Kar
Source:
Foods 2022 v.11 no.4 pp. -
ISSN:
2304-8158
Subject:
lycopene,   etc   ; Momordica charantia; formic acid; grapefruits; horticulture; temperature;     Show all 6 Subjects
Abstract:
... A quick, simple, and reliable isocratic ultra-performance supercritical fluid chromatography-photodiode array detector (UPSFC-DAD) method was developed and validated to determine lycopene in different horticultural products. The effects of stationary phase, co-solvent, pressure, temperature, flow rate, and mobile phase additive on the separation of lycopene were evaluated. The developed method inv ...
DOI:
10.3390/foods11040522

3. Effect of Molecular Distortion on the Optical Properties of Carotenoid-Based Nanoparticles

Author:
Ryuju Suzuki; Kazuma Yasuhara; Shigeru Deguchi
Source:
Journal of physical chemistry 2022 v.126 no.5 pp. 2607-2613
ISSN:
1932-7455
Subject:
lycopene,   etc   ; Raman spectroscopy; absorption; astaxanthin; lutein; transmission electron microscopy;     Show all 6 Subjects
Abstract:
... Tuning the conformations of flexible molecules has recently shown promise as a strategy for creating new materials. However, the creation of soft-molecule materials remains challenging because these materials are typically characterized without fully considering the contribution of molecular distortion. Carotenoids are flexible, polyene-based molecules that are prone to molecular distortion, which ...
DOI:
10.1021/acs.jpcc.1c08572

4. Bio-Availability, Anticancer Potential, and Chemical Data of Lycopene: An Overview and Technological Prospecting

Author:
Adriany das Graças Nascimento Amorim; Andreanne Gomes Vasconcelos; Jessica Souza; Ana Oliveira; Beatriz Gullón; José Roberto de Souza de Almeida Leite; Manuela Pintado
Source:
Antioxidants 2022 v.11 no.2 pp. -
ISSN:
2076-3921
Subject:
lycopene,   etc   ; antioxidants; bioavailability; biosynthesis; cytotoxicity; encapsulation; fluorescence; humans; isomers; permeability;     Show all 10 Subjects
Abstract:
... The purpose of this review was to collect relevant chemical data about lycopene and its isomers, which can be extracted using different non-polar or polar aprotic solvents by SC-CO₂ or biosynthesis as a friendly technique. Lycopene and other carotenoids can be identified and quantified by UV–Vis and HPLC using a C18 or C30 column, while their characterization is possible by UV–Vis, Fluorescence, F ...
DOI:
10.3390/antiox11020360

5. Efficient E/Z conversion of (all-E)-lycopene to Z-isomers with a high proportion of (5Z)-lycopene by metal salts

Author:
Qun Wang; Cheng Yang; Yuanyuan Liu; Jian Zhang; Lianfu Zhang
Source:
Lebensmittel-Wissenschaft + Technologie 2022 v.160 pp. 113268
ISSN:
0023-6438
Subject:
lycopene,   etc   ; activation energy; catalysts; catalytic activity; cis-trans isomers; isomerization;     Show all 6 Subjects
Abstract:
... In this paper, the effects of eleven metal salts on the isomerization and stability of lycopene were screened. The results showed that AlCl₃, Al₂(SO₄)₃, FeCl₃, Fe₂(SO₄)₃, and CuSO₄ had significant catalytic effects (p < 0.05) on lycopene isomerization. The total content of lycopene Z-isomers were in the order of FeCl₃ (70.8%) > Fe₂(SO₄)₃ (54.0%) > AlCl₃ (50.2%) > CuSO₄ (40.0%) > Al₂(SO₄)₃ (29.3%) ...
DOI:
10.1016/j.lwt.2022.113268

6. Lycopene ameliorates atrazine-induced pyroptosis in spleen by suppressing the Ox-mtDNA/Nlrp3 inflammasome pathway

Author:
Shi-Yong Zhu; Jian-Ying Guo; Jin-Yang Li; Xue-Yan Dai; Xue-Nan Li; Jin-Long Li
Source:
Food & function 2022 v.13 no.6 pp. 3551-3560
ISSN:
2042-650X
Subject:
lycopene,   etc   ; agricultural industry; atrazine; bioactive compounds; inflammasomes; oxidative stress; pyroptosis; spleen;     Show all 8 Subjects
Abstract:
... Nlrp3 is a vital integration point of diverse extracellular stimuli and cellular stress. However, the inappropriate activation of Nlrp3 results in the progression of autoinflammatory and metabolic disorders. Atrazine, which is used widely in the agricultural sector, is toxic to humans. Herein, this study found that atrazine could induce oxidative stress and the expression of Nfkb and IRF1 in splee ...
DOI:
10.1039/d1fo02857j

7. Optimization of the Isopentenol Utilization Pathway for Isoprenoid Synthesis in Escherichia coli

Author:
Xiaoqiang Ma; Hong Liang; Qiuchi Pan; Kristala L. J. Prather; Anthony J. Sinskey; Gregory Stephanopoulos; Kang Zhou
Source:
Journal of agricultural and food chemistry 2022 v.70 no.11 pp. 3512-3520
ISSN:
1520-5118
Subject:
lycopene,   etc   ; Escherichia coli; biomass; carbon metabolism; cell growth; enzymes; food chemistry;     Show all 7 Subjects
Abstract:
... Engineering microbes to produce isoprenoids can be limited by the competition between product formation and cell growth because biomass and isoprenoids are naturally derived from central metabolism. Recently, a two-step synthetic pathway was developed to partially decouple isoprenoid formation from central carbon metabolism. The pathway used exogenously added isopentenols as substrates. In the pre ...
DOI:
10.1021/acs.jafc.2c00014

8. Phytoene synthase 2 in tomato fruits remains functional and contributes to abscisic acid formation

Author:
Prateek Gupta; Marta Rodriguez‐Franco; Reddaiah Bodanapu; Yellamaraju Sreelakshmi; Rameshwar Sharma
Source:
Plant science 2022 v.316 pp. 111177
ISSN:
0168-9452
Subject:
lycopene,   etc   ; abscisic acid; biosynthesis; chloroplasts; chromoplasts; mutants; phytoene synthase; tomatoes; triethylamine;     Show all 9 Subjects
Abstract:
... In ripening tomato fruits, the leaf-specific carotenoids biosynthesis mediated by phytoene synthase 2 (PSY2) is replaced by a fruit-specific pathway by the expression of two chromoplast-specific genes: phytoene synthase 1 (PSY1) and lycopene-β-cyclase (CYCB). Though both PSY1 and PSY2 genes express in tomato fruits, the functional role of PSY2 is not known. To decipher whether PSY2-mediated carote ...
DOI:
10.1016/j.plantsci.2022.111177

9. What Is the Current Direction of the Research on Carotenoids and Human Health? An Overview of Registered Clinical Trials

Author:
Daniela Martini; Letizia Negrini; Mirko Marino; Patrizia Riso; Cristian Del Bo; Marisa Porrini
Source:
Nutrients 2022 v.14 no.6 pp. -
ISSN:
2072-6643
Subject:
lycopene,   etc   ; astaxanthin; bioavailability; cognition; eyes; human health; lutein; metabolism; microorganisms; vision;     Show all 10 Subjects
Abstract:
... Carotenoids have been the object of numerous observational, pre-clinical and interventional studies focused on elucidating their potential impacts on human health. However, the large heterogeneity among the trials, in terms of study duration and characteristics of participants, makes any conclusion difficult to draw. The present study aimed to explore the current carotenoid research trends by anal ...
DOI:
10.3390/nu14061191

10. Are We Sentenced to Pharmacotherapy? Promising Role of Lycopene and Vitamin A in Benign Urologic Conditions

Author:
Piotr Kutwin; Piotr Falkowski; Roman Łowicki; Magdalena Borowiecka-Kutwin; Tomasz Konecki
Source:
Nutrients 2022 v.14 no.4 pp. -
ISSN:
2072-6643
Subject:
lycopene,   etc   ; drug therapy; hyperplasia; medicine; prostatitis; rats; urinary tract; urolithiasis; vitamin A;     Show all 9 Subjects
Abstract:
... Benign prostatic hyperplasia, urolithiasis, recurrent urinary tract infections, and chronic prostatitis are diseases that are commonly diagnosed worldwide. Carotenoids, including lycopene, are widely available in fruits and vegetables, and it is postulated that they can be used in the prevention and treatment of benign urological conditions. The aim of this review is to familiarize doctors and the ...
DOI:
10.3390/nu14040859

11. DNA methylation mediated by melatonin was involved in ethylene signal transmission and ripening of tomato fruit

Author:
Shuangshuang Shan; Zhiqiang Wang; Huili Pu; Wenhui Duan; Hongmiao Song; Jiangkuo Li; Zhengke Zhang; Xiangbin Xu
Source:
Scientia horticulturae 2022 v.291 pp. 110566
ISSN:
0304-4238
Subject:
lycopene,   etc   ; DNA methylation; ascorbic acid; color; ethylene; fruits; genomic islands; melatonin; tomatoes;     Show all 9 Subjects
Abstract:
... Melatonin (MT) as an evolutionarily highly conserved molecule plays an exceptional role in plants. In the present study, the regulation mechanism of the DNA methylation of CpG islands of ethylene signaling genes induced by MT on postharvest ripening of tomato fruit was studied. The ripening of tomato fruit was significantly promoted by the 0.5 mM MT treatment, as revealed by the appearance color, ...
DOI:
10.1016/j.scienta.2021.110566

12. Improving tomato juice concentration process through a novel ultrasound-thermal concentrator under vacuum condition: A bioactive compound investigation and optimization

Author:
Behnam Alaei; Reza Amiri Chayjan; Mohammad Ali Zolfigol
Source:
Innovative food science & emerging technologies 2022 v.77 pp. 102983
ISSN:
1466-8564
Subject:
lycopene,   etc   ; ascorbic acid; bioactive compounds; energy; food science; temperature; tomato juice; ultrasonics;     Show all 8 Subjects
Abstract:
... We investigated the simultaneous effects of temperature, ultrasound, and vacuum pressure in the tomato juice concentration process. To this end, a novel ultrasound-thermal concentrator under vacuum conditions was fabricated. The process was performed at three levels of ultrasound power (48, 84, and 120 W), three vacuum pressures (10, 20, and 30 kPa), and three temperatures (50, 60, and 70 °C). Als ...
DOI:
10.1016/j.ifset.2022.102983

13. Upstream Activation Sequence Can Function as an Insulator for Chromosomal Regulation of Heterologous Pathways Against Position Effects in Saccharomyces cerevisiae

Author:
Buli Su; Fan Yang; Anzhang Li; Ming-Rong Deng; Honghui Zhu
Source:
Applied biochemistry and biotechnology 2022 v.194 no.4 pp. 1841-1849
ISSN:
0273-2289
Subject:
lycopene,   etc   ; Saccharomyces cerevisiae; biochemical pathways; biosynthesis; biotechnology; gene order; genes; manufacturing; transcription (genetics);     Show all 9 Subjects
Abstract:
... Metabolic engineering of microbial cell factories through integrating the heterologous synthetic pathway into the chromosome is most commonly used for industrial applications. However, the position of the foreign gene in the chromosome can affect its transcriptional level. As a microorganism that is generally regarded as safe (GRAS) and commonly applied in industrial manufacture with large-scale o ...
DOI:
10.1007/s12010-021-03654-1

14. Assessment and characterization of tomato lipophilic electrophiles and their potential contribution to nutraceutical properties via SKN-1/Nrf2 signaling activation

Author:
Andrea del Valle Carranza; Gustavo Bonacci; Yanina Moran; Pablo Asprelli; Fernando Carrari; Ramón Asis
Source:
Food chemistry 2022 v.366 pp. 130531
ISSN:
0308-8146
Subject:
lycopene,   etc   ; Lewis acids; Lewis bases; dietary supplements; food chemistry; homeostasis; lipophilicity; oxidation; phytochemicals; tomatoes;     Show all 10 Subjects
Abstract:
... Phytochemical electrophiles are drawing significant attention due to their properties to modulate signaling pathways related to cellular homeostasis. The aim of this study was to develop new tools to examine the electrophilic activity in food and predict their beneficial effects on health. We developed a spectrophotometric assay based on the nitrobenzenethiol (NBT) reactivity, as a thiol-reactive ...
DOI:
10.1016/j.foodchem.2021.130531

15. Overexpression of RmLCYB from Rhododendron molle increases carotenoid in Nicotiana tabacum

Author:
Zheng Xiao; Jiale Su; Xiaoqing Liu; Xiaobo Sun; Lisi He; Huimin Zhou; Chang Li
Source:
Acta physiologiae plantarum 2022 v.44 no.7 pp. 71
ISSN:
0137-5881
Subject:
lycopene,   etc   ; Nicotiana tabacum; Rhododendron; amino acid sequences; biosynthesis; color; flower color; flowering; genes; tobacco;     Show all 10 Subjects
Abstract:
... Rhododendron molle G. Don is a deciduous species of Rhododendron with unique yellow flowers. Carotenoids play a major role in flower coloration. Lycopene β-cyclase (LCYB) is an essential enzyme which catalyzes the synthesis of β-carotene from lycopene in the carotenoid biosynthesis pathway. However, the molecular function of the LCYB gene in R. molle remains unknown. In this study, the RmLCYB gene ...
DOI:
10.1007/s11738-022-03403-9

16. Black pepper and vegetable oil-based emulsion synergistically enhance carotenoid bioavailability of raw vegetables in humans

Author:
Haiyan Luo; Zhengze Li; Chad R. Straight; Qi Wang; Jiazhi Zhou; Yukun Sun; Chia-yu Lo; Lingxiao Yi; Yanyan Wu; Jingyuan Huang; William Wolfe; Dianne Z. Sutherland; Mark S. Miller; David Julian McClements; Eric A. Decker; Hang Xiao
Source:
Food chemistry 2022 v.373 pp. 131277
ISSN:
0308-8146
Subject:
lycopene,   etc   ; bioavailability; black pepper; canola; canola oil; cross-over studies; emulsions; food chemistry; lutein; salads; vegetables;     Show all 11 Subjects
Abstract:
... This study demonstrated the combination of black pepper and a canola oil-based emulsion synergistically enhanced carotenoid bioavailability of raw vegetables in humans. In a randomized crossover design, healthy young adults consumed (1) vegetable salad (control), (2) salad with canola oil emulsion (COE), (3) salad with black pepper (BP), and (4) salad with canola oil emulsion and black pepper (COE ...
DOI:
10.1016/j.foodchem.2021.131277

17. Measurement of lactose concentration in milk by using engineered bacteria producing lycopene

Author:
Yinjie Li; Qunqun Guo; Tingting Zhang; Chao Wang; Hong Yang; Guicai Du; Ronggui Li
Source:
Journal of microbiological methods 2022 v.194 pp. 106390
ISSN:
0167-7012
Subject:
lycopene,   etc   ; Escherichia coli; bacterial culture; genetic transformation; high performance liquid chromatography; lactose; milk; phenotype; plasmids; spectrophotometers;     Show all 10 Subjects
Abstract:
... Lycopene is an orange–red carotenoid, which confers a visual phenotype to assess genetic transformation of microorganisms. In this study, the lycopene synthesis pathway was constructed in engineered Escherichia coli BL21 (DE3) by transforming plasmid pET-15b-crtBEI, wherein crtB, crtE, and crtI could be expressed under the control of the T7 promoter and lacO operator and lycopene could be accumula ...
DOI:
10.1016/j.mimet.2021.106390

18. Regulation of platelet function by natural bioactive compounds

Author:
Meiby Fernández-Rojas; Lyanne Rodríguez; Andrés Trostchansky; Eduardo Fuentes
Source:
Food bioscience 2022 v.48 pp. 101742
ISSN:
2212-4292
Subject:
lycopene,   etc   ; atherosclerosis; blood vessels; diet; flavonoids; metabolites; mortality; myocardial infarction; platelet aggregation; risk factors; risk reduction;     Show all 11 Subjects
Abstract:
... Cardiovascular diseases rank first in mortality worldwide. Platelets have been considered the main cardiovascular risk factor since they play an important role, in atherosclerosis and the development of acute thrombotic events. The hyperactivation of platelets leads to platelet aggregation and the formation of clogs, blocking the passage of blood to the different organs and tissues. Blood obstruct ...
DOI:
10.1016/j.fbio.2022.101742

19. The encapsulation of lycopene with α-lactalbumin nanotubes to enhance their anti-oxidant activity, viscosity and colloidal stability in dairy drink

Author:
Ruxin Chang; Bin Liu; Qimeng Wang; Jipeng Zhang; Fang Yuan; Huijuan Zhang; Shanan Chen; Shuang Liang; Yuan Li
Source:
Food hydrocolloids 2022 v.131 pp. 107792
ISSN:
0268-005X
Subject:
lycopene,   etc   ; antioxidant activity; antioxidants; encapsulation; hydrocolloids; hydrophobic bonding; hydrophobicity; intestines; nanospheres; nanotubes; temperature; ultraviolet radiation; viscosity;     Show all 13 Subjects
Abstract:
... Nano-encapsulation is promising in improving the stability and biological activity of bioactive compounds. Here, the food-sourced protein nanotubes (NTs) from self-assembly of partially hydrolyzed α-lactalbumin (α-lac) were developed. The α-lac NTs had a dimension of 20 nm in diameter and 200–1000 nm in length. Lycopene (LYC) was loaded into the hydrophobic inner wall of NTs via hydrophobic intera ...
DOI:
10.1016/j.foodhyd.2022.107792

20. Spatiotemporal distribution of chemical signatures exhibited by Myxococcus xanthus in response to metabolic conditions

Author:
Hyein Do; Chinedu S. Madukoma; Vignesh Sundaresan; Joshua D. Shrout; Anthony J. Hoffman; Paul W. Bohn
Source:
Analytical and bioanalytical chemistry 2022 v.414 no.4 pp. 1691-1698
ISSN:
1618-2642
Subject:
lycopene,   etc   ; Myxococcus xanthus; Raman imaging; analytical chemistry; heat; nutrient availability; principal component analysis; secondary metabolites; soil bacteria;     Show all 9 Subjects
Abstract:
... Myxococcus xanthus is a common soil bacterium with a complex life cycle, which is known for production of secondary metabolites. However, little is known about the effects of nutrient availability on M. xanthus metabolite production. In this study, we utilize confocal Raman microscopy (CRM) to examine the spatiotemporal distribution of chemical signatures secreted by M. xanthus and their response ...
DOI:
10.1007/s00216-021-03795-6