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1. Identification of a major locus for flowering pattern sheds light on plant architecture diversification in cultivated peanut

Author:
Srinivas Kunta; Ye Chu; Yael Levy; Arye Harel; Shahal Abbo; Peggy Ozias-Akins; Ran Hovav
Source:
Theoretical and applied genetics 2022 v.135 no.5 pp. 1767-1777
ISSN:
0040-5752
Subject:
major genes,   etc   ; Arachis hypogaea; domestication; gene conversion; gene expression; loci; peanuts; phenotype; plant architecture; sequence analysis;     Show all 10 Subjects
Abstract:
... KEY MESSAGE: A major gene controls flowering pattern in peanut, possibly encoding a TFL1-like. It was subjected to gain/loss events of a deletion and changes in mRNA expression levels, partly explaining the evolution of flowering pattern in Arachis. Flowering pattern (FP) is a major characteristic differentiating the two subspecies of cultivated peanut (Arachis hypogaea L.). Subsp. fastigiata poss ...
DOI:
10.1007/s00122-022-04068-1

2. The inheritance of betalain pigmentation in Basella alba L.

Author:
Vidya Sagar; Pragya; Rakesh Bhardwaj; Jyoti Devi; Sunil K Singh; PM Singh; Jagdish Singh
Source:
South African journal of botany 2022 v.145 pp. 360-369
ISSN:
0254-6299
Subject:
major genes,   etc   ; Basella alba; antioxidant activity; betalains; dominant genes; flowers; fruits; genotype; pigmentation; therapeutics; vegetables; India;     Show all 12 Subjects
Abstract:
... Basella alba is an underutilized leafy vegetable native to the Indian subcontinent. The therapeutic function associated with the consumption of this vegetable is well known, such as androgenic, anti-diabetic, anti-inflammatory and antioxidant activity. The plant's fruit and stem are blessed with natural betalain pigments. In the recent years, researchers have developed an increasing interest in th ...
DOI:
10.1016/j.sajb.2022.01.033

3. Identification and validation of a major gene for kernel length at the P1 locus in Triticum polonicum

Author:
Songyue Chai; Qin Yao; Rui Liu; Wenhui Xiang; Xue Xiao; Xing Fan; Jian Zeng; Lina Sha; Houyang Kang; Haiqin Zhang; Dan Long; Dandan Wu; Yonghong Zhou; Yi Wang
Source:
crop journal 2022 v.10 no.2 pp. 387-396
ISSN:
2214-5141
Subject:
major genes,   etc   ; Triticum; alternative splicing; brassinosteroids; cultivars; introns; loci; quantitative polymerase chain reaction; quantitative traits; seeds; sequence deletion; wheat;     Show all 12 Subjects
Abstract:
... Kernel size, one of the traits that determine wheat yield, is controlled by multiple quantitative trait loci. Polish wheat (Triticum polonicum) has elongated and plump kernel and is a valuable material for breeding high-yielding wheat cultivars. However, genes or loci determining kernel length (KL) in Polish wheat are unknown. We identified and validated a major KL gene, KL-PW, at the P1 locus in ...
DOI:
10.1016/j.cj.2021.07.006

4. BSA‐seq and quantitative trait locus mapping reveals a major effective QTL for carpel number in watermelon (Citrullus lanatus)

Author:
Boyan Qiu; Taifeng Zhang; Shuqing Zhang; Qianrui Qu; Zicheng Zhu; Shusen Liu; Zhengfeng Song; Lianqin Xia; Zhongzhou Yang; Qian Zhang; Feishi Luan; Peng Gao; Shi Liu
Source:
Plant breeding 2022 v.141 no.3 pp. 460-470
ISSN:
0179-9541
Subject:
major genes,   etc   ; Citrullus lanatus; backcrossing; chromosomes; computer software; frequency distribution; fruit morphology; inheritance (genetics); protein kinases; quantitative trait loci; watermelons;     Show all 11 Subjects
Abstract:
... The carpel number (CN) is related to fruit shape variation in watermelon and represents one of the most important agronomic traits. In this study, ZXG01553 (5‐CN type) and W1‐17 (3‐CN type) lines were used as parental material to construct F₁, F₂ and backcross populations for genetic inheritance analysis and QTL (quantitative trait locus) mapping. The F₁ generation displayed the 3‐CN type and the ...
DOI:
10.1111/pbr.13015

5. QTL mapping of polymethoxyflavone (PMF) accumulation in citrus

Author:
Yomi Matsumoto; Takehiro Kubo; Yuri Itami; Md. Zaherul Islam; Satoshi Watanabe; Nobuhiro Kotoda
Source:
Tree genetics & genomes 2022 v.18 no.1 pp. 7
ISSN:
1614-2942
Subject:
major genes,   etc   ; Citrus; biochemical pathways; biosynthesis; chromosome mapping; flavanone 3-dioxygenase; genetic distance; genotyping; health promotion; methyltransferases; plant genetics; polymethoxyflavones; quantitative trait loci; single nucleotide polymorphism;     Show all 14 Subjects
Abstract:
... Polymethoxyflavones (PMFs) are bioactive flavonoids exclusively found in the genus citrus, and they show various health-promoting activities. Researchers have studied the biosynthesis of PMFs and focused on isolation and characterization of the responsible genes. However, our knowledge about the biosynthesis of PMFs is still limited. In this study, we aimed to reveal the loci for causative factors ...
DOI:
10.1007/s11295-022-01539-w

6. GeneCaRNA: A Comprehensive Gene-centric Database of Human Non-coding RNAs in the GeneCards Suite

Author:
Ruth Barshir; Simon Fishilevich; Tsippi Iny-Stein; Ofer Zelig; Yaron Mazor; Yaron Guan-Golan; Marilyn Safran; Doron Lancet
Source:
Journal of molecular biology 2021 v.433 no.11 pp. 166913
ISSN:
0022-2836
Subject:
major genes,   etc   ; databases; humans; molecular biology; non-coding RNA;     Show all 5 Subjects
Abstract:
... Non-coding RNA (ncRNA) genes assume increasing biological importance, with growing associations with diseases. Many ncRNA sources are transcript-centric, but for non-coding variant analysis and disease decipherment it is essential to transform this information into a comprehensive set of genome-mapped ncRNA genes. We present GeneCaRNA, a new all-inclusive gene-centric ncRNA database within the Gen ...
DOI:
10.1016/j.jmb.2021.166913

7. Genomic and GWAS analyses demonstrate phylogenomic relationships of Gossypium barbadense in China and selection for fibre length, lint percentage and Fusarium wilt resistance

Author:
Nan Zhao; Weiran Wang; Corrinne E. Grover; Kaiyun Jiang; Zhuanxia Pan; Baosheng Guo; Jiahui Zhu; Ying Su; Meng Wang; Hushuai Nie; Li Xiao; Anhui Guo; Jing Yang; Cheng Cheng; Xinmin Ning; Bin Li; Haijiang Xu; Daniel Adjibolosoo; Alifu Aierxi; Pengbo Li; Junyi Geng; Jonathan F. Wendel; Jie Kong; Jinping Hua
Source:
Plant biotechnology journal 2022 v.20 no.4 pp. 691-710
ISSN:
1467-7644
Subject:
major genes,   etc   ; Fusarium wilt; Gossypium barbadense; biotechnology; disease resistance; fiber quality; gene expression; genetically modified organisms; genome-wide association study; genomics; germplasm; lint cotton; pedigree; phylogeny; plant architecture; population structure; China;     Show all 17 Subjects
Abstract:
... Sea Island cotton (Gossypium barbadense) is the source of the world’s finest fibre quality cotton, yet relatively little is understood about genetic variations among diverse germplasms, genes underlying important traits and the effects of pedigree selection. Here, we resequenced 336 G. barbadense accessions and identified 16 million SNPs. Phylogenetic and population structure analyses revealed two ...
DOI:
10.1111/pbi.13747

8. Comparative Association Mapping Reveals Conservation of Major Gene Resistance to White Pine Blister Rust in Southwestern White Pine (Pinus strobiformis) and Limber Pine (P. flexilis)

Author:
Jun-Jun Liu; Anna W. Schoettle; Richard A. Sniezko; Kristen M. Waring; Holly Williams; Arezoo Zamany; Jeremy S. Johnson; Angelia Kegley
Source:
Phytopathology 2022 v.112 no.5 pp. 1093-1102
ISSN:
0031-949X
Subject:
major genes,   etc   ; Cronartium ribicola; Pinus flexilis; Pinus strobiformis; amino acids; genetic resistance; genetic variation; genotyping; hybrids; linkage groups; loci; marker-assisted selection; pectins; plant pathology; single nucleotide polymorphism; white pine blister rust;     Show all 16 Subjects
Abstract:
... All native North American white pines are highly susceptible to white pine blister rust (WPBR) caused by Cronartium ribicola. Understanding genomic diversity and molecular mechanisms underlying genetic resistance to WPBR remains one of the great challenges in improvement of white pines. To compare major gene resistance (MGR) present in two species, southwestern white pine (Pinus strobiformis) Cr3 ...
DOI:
10.1094/PHYTO-09-21-0382-R

9. SNPs in a Large Genomic Scaffold Are Strongly Associated with Cr1ᴿ, Major Gene for Resistance to White Pine Blister Rust in Range-Wide Samples of Sugar Pine (Pinus lambertiana)

Author:
Jessica W. Wright; Kristian A. Stevens; Paul Hodgskiss; Charles H. Langley
Source:
Plant disease 2022 v.106 no.6 pp. 1639-1644
ISSN:
0191-2917
Subject:
major genes,   etc   ; Cronartium ribicola; DNA; Oregon; Pinus lambertiana; alleles; diploidy; forest restoration; fungi; genetic improvement; genomics; genotyping; geographical distribution; keystone species; pathogens; phenotype; polymerase chain reaction; resistance genes; white pine blister rust; Mexico;     Show all 20 Subjects
Abstract:
... Sugar pine, Pinus lambertiana Douglas, is a keystone species of montane forests from Baja California to southern Oregon. Like other North American white pines, populations of sugar pine have been greatly reduced by the disease white pine blister rust (WPBR) caused by a fungal pathogen, Cronartium ribicola, that was introduced into North America early in the twentieth century. Major gene resistance ...
DOI:
10.1094/PDIS-08-21-1608-RE

10. Gene-Based Association Testing of Dichotomous Traits With Generalized Functional Linear Mixed Models Using Extended Pedigrees: Applications to Age-Related Macular Degeneration

Author:
Yingda Jiang; Chi-Yang Chiu; Qi Yan; Wei Chen; Michael B. Gorin; Yvette P. Conley; M’Hamed Lajmi Lakhal-Chaieb; Richard J. Cook; Christopher I. Amos; Alexander F. Wilson; Joan E. Bailey-Wilson; Francis J. McMahon; Ana I. Vazquez; Ao Yuan; Xiaogang Zhong; Momiao Xiong; Daniel E. Weeks; Ruzong Fan
Source:
Journal of the American Statistical Association 2021 v.116 no.534 pp. 531-545
ISSN:
1537-274X
Subject:
major genes,   etc   ; blindness; elderly; inflammation; kinship; macular degeneration; oxidative stress; pedigree; seeds; statistics;     Show all 10 Subjects
Abstract:
... Genetics plays a role in age-related macular degeneration (AMD), a common cause of blindness in the elderly. There is a need for powerful methods for carrying out region-based association tests between a dichotomous trait like AMD and genetic variants on family data. Here, we apply our new generalized functional linear mixed models (GFLMM) developed to test for gene-based association in a set of A ...
DOI:
10.1080/01621459.2020.1799809

11. Polymorphism Detection of GDF9 Gene and Its Association with Litter Size in Luzhong Mutton Sheep (Ovis aries)

Author:
Fengyan Wang; Mingxing Chu; Linxiang Pan; Xiangyu Wang; Xiaoyun He; Rensen Zhang; Lin Tao; Yongfu La; Lin Ma; Ran Di
Source:
Animals 2021 v.11 no.2 pp. -
ISSN:
2076-2615
Subject:
major genes,   etc   ; Ovis aries; fecundity; genotyping; linear models; litter size; missense mutation; mutton;     Show all 8 Subjects
Abstract:
... Litter size is one of the most important economic traits in sheep. GDF9 and BMPR1B are major genes affecting the litter size of sheep. In this study, the whole coding region of GDF9 was sequenced and all the SNPs (single nucleotide polymorphisms) were determined in Luzhong mutton ewes. The FecB mutation was genotyped using the Sequenom MassARRAY®SNP assay technology. Then, the association analyses ...
DOI:
10.3390/ani11020571

12. Association Analysis between Genetic Variants of elovl5a and elovl5b and Poly-Unsaturated Fatty Acids in Common Carp (Cyprinus carpio)

Author:
Yan Zhang; Qing-Song Li; Yu-Qing Ye; Qi Wang; Xiao-Qing Sun; Ran Zhao; Jiong-Tang Li
Source:
Biology 2022 v.11 no.3 pp. -
ISSN:
2079-7737
Subject:
major genes,   etc   ; Cyprinus carpio; allotetraploidy; biosynthesis; food animals; heterozygosity; homozygosity; marker-assisted selection;     Show all 8 Subjects
Abstract:
... The allo-tetraploid common carp, one widely cultured food fish, is able to produce poly-unsaturated fatty acids (PUFAs). The genetic markers on the PUFA contents for breeding was limited. The polymorphisms in elovl5a and elovl5b, the rate-limiting enzymes in the PUFA biosynthesis, have not been investigated yet. Herein, we identified one coding SNP (cSNP) in elovl5a associated with the content of ...
DOI:
10.3390/biology11030466

13. Variation and inheritance of the degree of style branching in hybrids of Iris dichotoma × I. domestica

Author:
Jingli Gao; Wenjing Cai; Yuee Xiao; Fengyang Yu; Yang Zheng; Xiaoying Bi
Source:
Scientia horticulturae 2021 v.288 pp. 110303
ISSN:
0304-4238
Subject:
major genes,   etc   ; Iris dichotoma; additive effect; ecological function; epistasis; genetic models; heritability; progeny; reproduction;     Show all 9 Subjects
Abstract:
... The degree of style branching is an important characteristic for classification, reproduction and ecological function in the Iridaceae family. We established 6 generations derived from Iris dichotoma and I. domestica, and calculated the style branch ratio (the ratio of each style branch to the whole style in length) to express the branching degree of style. The variation of style branch ratio was ...
DOI:
10.1016/j.scienta.2021.110303

14. Inheritance of resistance to the newly identified Plasmodiophora brassicae pathotypes in Brassica napus L.

Author:
Rubeena Shaikh; Mehdi Farid; Habibur Rahman
Source:
Canadian journal of plant pathology 2021 v.43 no.2 pp. 256-266
ISSN:
1715-2992
Subject:
major genes,   etc   ; Brassica napus; Plasmodiophora brassicae; canola; clubroot; cultivars; doubled haploids; pathotypes; plant pathology; virulence; Canada;     Show all 11 Subjects
Abstract:
... Clubroot disease caused by Plasmodiophora brassicae Woronin is one of the most devastating diseases of canola (Brassica napus L.). Pathotype 3H has been the most prevalent and virulent pathotype in western Canada. Many resistant cultivars have been developed in Canada in recent years. However, large-scale cultivation of these cultivars resulted in the identification of several new virulent pathoty ...
DOI:
10.1080/07060661.2020.1823483

15. Major gene with polygene inheritance analysis of shoot architecture traits in Viola cornuta

Author:
Xiaohua Du; Hu Wang; Jiayi Liu; Xiaopei Zhu; Jinyan Mu; Xiandan Feng; Huichao Liu
Source:
Scientia horticulturae 2022 v.303 pp. 111204
ISSN:
0304-4238
Subject:
major genes,   etc   ; Viola cornuta; aesthetics; genetic analysis; genetic models; genetic variance; heritability; pedicel; quantitative trait loci;     Show all 9 Subjects
Abstract:
... The shoot architecture of Viola cornuta affects its uniformity, aesthetics, and lodging resistance. Understanding the genetic variance in the traits of the shoot architecture has practical significance for V. cornuta breeding. However, not much is currently known about these traits. In this study, we analyzed the genetic basis of seven traits (plant height-PH, plant width-PW, plant width/plant hei ...
DOI:
10.1016/j.scienta.2022.111204

16. Detection of Novel Variations Related to Litter Size in BMP15 Gene of Luzhong Mutton Sheep (Ovis aries)

Author:
Ran Di; Fengyan Wang; Ping Yu; Xiangyu Wang; Xiaoyun He; Joram Mwashigadi Mwacharo; Linxiang Pan; Mingxing Chu
Source:
Animals 2021 v.11 no.12 pp. -
ISSN:
2076-2615
Subject:
major genes,   etc   ; Ovis aries; alleles; geographical distribution; linear models; litter size; mutton; sheep industry; Western European region;     Show all 9 Subjects
Abstract:
... Litter size is an important economic trait in the mutton sheep industry. BMP15 is one of the key candidate genes for litter size in sheep. In this study, the entire ORF region of BMP15 was sequenced in 154 Luzhong mutton ewes, and the novel variations were determined. The association between polymorphism in BMP15 and litter size was analyzed using a general linear model. Six out of a total of thir ...
DOI:
10.3390/ani11123528

17. Breeding with Major and Minor Genes: Genomic Selection for Quantitative Disease Resistance

Author:
Merrick Lance F.; Burke Adrienne B.; Chen Xianming; Carter Aaron H.
Source:
Frontiers in plant science 2021 v.12 no. pp. 713667
ISSN:
1664-462X
Subject:
major genes,   etc   ; Puccinia striiformis; Triticum aestivum; disease resistance; disease severity; marker-assisted selection; models; prediction; stripe rust; wheat;     Show all 10 Subjects
Abstract:
... Most disease resistance in plants is quantitative, with both major and minor genes controlling resistance. This research aimed to optimize genomic selection (GS) models for use in breeding programs needing to select both major and minor genes for resistance. In this experiment, stripe rust (Puccinia striiformis Westend. f. sp. tritici Erikss.) of wheat (Triticum aestivum L.) was used as a model fo ...
Handle:
10113/7709602
DOI:
10.3389/fpls.2021.713667

18. Germplasm screening and inheritance analysis of resistance to cabbage black rot in a worldwide collection of cabbage (Brassica oleracea var. capitata) resources

Author:
Congcong Kong; Guo Chen; Limei Yang; Mu Zhuang; Yangyong Zhang; Yong Wang; Jialei Ji; Zhiyuan Fang; Honghao Lv
Source:
Scientia horticulturae 2021 v.288 pp. 110234
ISSN:
0304-4238
Subject:
major genes,   etc   ; Brassica oleracea var. capitata; Xanthomonas campestris pv. campestris; cabbage; cultivars; germplasm; inoculation methods; models; resistance genes;     Show all 9 Subjects
Abstract:
... Xanthomonas campestris pv. campestris (Xcc) is the causal agent of cabbage (Brassica oleracea var. capitata) black rot (BR) that leads to severe yield losses worldwide. Cultivation and application of resistant cultivars is the most desirable way to control BR. However, due to the lack of BR-resistant germplasm resources and an unclear understanding of the resistance inheritance as well as the cont ...
DOI:
10.1016/j.scienta.2021.110234

19. Heritability and Genomic Architecture of Episodic Exercise-Induced Collapse in Border Collies

Author:
Elaine M. Norton; Katie M. Minor; Susan M. Taylor; Molly E. McCue; James R. Mickelson
Source:
Genes 2021 v.12 no.12 pp. -
ISSN:
2073-4425
Subject:
major genes,   etc   ; Collie; dogs; exercise; genetic disorders; genomics; genotype; genotyping; heritability; nervous system diseases; phenotype; single nucleotide polymorphism;     Show all 12 Subjects
Abstract:
... An episodic nervous system disorder triggered by strenuous exercise, termed border collie collapse (BCC), exists in border collies and related breeds. The genetic basis of BCC is unknown but is believed to be a complex genetic disorder. Our goal was to estimate the heritability (h²SNP) of BCC, define its underlying genetic architecture, and identify associated genomic loci using dense whole-genome ...
DOI:
10.3390/genes12121927

20. Transcriptomic changes in pancreatic islets, adipose and liver after Roux-en-Y gastric bypass in a diet-induced obese rat model

Author:
Chen Zhang; Lise Christine Biehl Rudkjær; Marisa Fernández Cachón; Mechthilde Falkenhahn; Stefan Theis; Thorsten Schmidt; Niels Vrang; Jacob Jelsing; Kristoffer Rigbolt
Source:
Peptides 2021 v.136 pp. 170467
ISSN:
0196-9781
Subject:
major genes,   etc   ; adipose tissue; bariatric surgery; gene expression; liver; low calorie diet; obesity; peptides; transcriptome; transcriptomics; weight loss;     Show all 11 Subjects
Abstract:
... Roux-en-Y gastric bypass (RYGB) is the most efficient intervention in morbid obesity and promotes metabolic improvements in several peripheral tissues. However, the underlying molecular mechanisms are still poorly understood. To further understand the effects of RYGB on peripheral tissues transcriptomes, we determined transcriptome signatures in pancreatic islets, adipose and liver tissue from die ...
DOI:
10.1016/j.peptides.2020.170467