U.S. flag

An official website of the United States government

Dot gov

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Https

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

PubAg

Main content area

You searched for: Subject "mammals" Remove constraint Subject: "mammals"
Start Over

Search

24,760  Search Results

« Previous | 1 - 20 of 24,760 |
Number of results to display per page

Search Results

1. Evaluating the taphonomic consistency of microvertebrate assemblages at Natural Trap Cave, Wyoming, USA

Author:
Jenny L. McGuire; Aaron Woodruff; Jennifer Iacono; Jadyn M. Sethna; Julia A. Schap; Cory M. Redman; Julie A. Meachen
Source:
Quaternary international 2022 v. no. pp. -
ISSN:
1040-6182
Subject:
mammals,   etc   ; Neotoma; nests; paleoecology; Wyoming;     Show all 5 Subjects
Abstract:
... Paleontological sites composed of small vertebrate specimens can contain hundreds-of-thousands of identifiable fossils, which can reveal community responses to environmental and trophic changes. However, the composition of these communities may be skewed if the taphonomic signatures of the deposits change over time and across strata. Here, we discuss the taphonomic processes that led to dense depo ...
DOI:
10.1016/j.quaint.2022.02.009

2. Predator-derived bioregions in the Southern Ocean: Characteristics, drivers and representation in marine protected areas

Author:
Ryan R. Reisinger; Cassandra M. Brooks; Ben Raymond; Jennifer J. Freer; Cédric Cotté; José C. Xavier; Philip N. Trathan; Horst Bornemann; Jean-Benoit Charrassin; Daniel P. Costa; Bruno Danis; Luis Hückstädt; Ian D. Jonsen; Mary-Anne Lea; Leigh Torres; Anton Van de Putte; Simon Wotherspoon; Ari S. Friedlaender; Yan Ropert-Coudert; Mark Hindell
Source:
Biological conservation 2022 v.272 pp. 109630
ISSN:
0006-3207
Subject:
mammals,   etc   ; biodiversity; habitats; water birds;     Show all 4 Subjects
Abstract:
... Multiple initiatives have called for large-scale representative networks of marine protected areas (MPAs). MPAs should be ecologically representative to be effective, but in large, remote regions this can be difficult to quantify and assess. We present a novel bioregionalization for the Southern Ocean, which uses the modelled circumpolar habitat importance of 17 marine bird and mammal species. The ...
DOI:
10.1016/j.biocon.2022.109630

3. Lfng and Dll3 cooperate to modulate protein interactions in cis and coordinate oscillatory Notch pathway activation in the segmentation clock

Author:
Matthew S. Bochter; Dustin Servello; Shinako Kakuda; Rachel D'Amico; Meaghan F. Ebetino; Robert S. Haltiwanger; Susan E. Cole
Source:
Developmental biology 2022 v.487 pp. 42-56
ISSN:
0012-1606
Subject:
mammals,   etc   ; epistasis; glycosylation; ligands; mesoderm; mutants;     Show all 6 Subjects
Abstract:
... In mammalian development, oscillatory activation of Notch signaling is required for segmentation clock function during somitogenesis. Notch activity oscillations are synchronized between neighboring cells in the presomitic mesoderm (PSM) and have a period that matches the rate of somite formation. Normal clock function requires cyclic expression of the Lunatic fringe (LFNG) glycosyltransferase, as ...
DOI:
10.1016/j.ydbio.2022.04.004

4. Comparative Evaluation of Pitfall Traps for Click Beetles (Coleoptera: Elateridae)

Author:
Willem G. van Herk; Robert S. Vernon; John H. Borden; Kathryn Ryan; Gareth Mercer
Source:
Journal of economic entomology 2022 v.115 no.2 pp. 582-591
ISSN:
0022-0493
Subject:
small mammals,   etc   ; Agriotes obscurus; entomology; pitfall traps;     Show all 4 Subjects
Abstract:
... We evaluated the relative efficacy of six pheromone-baited traps used in trapping Agriotes obscurus (L.) click beetles (Coleoptera: Elateridae): original Yatlor Traps, Yatlor Funnel Traps, Vernon Beetle Traps, Unitraps, Baited Pitfall Traps, and Vernon Pitfall Traps. Traps were rated according to quantitative and qualitative criteria of importance for each of four trap uses: general surveys, scien ...
DOI:
10.1093/jee/toab259

5. Dry-compression packing of hydroxyapatite nanoparticles within a flat cuboid chromatography device and its use for fast protein separation

Author:
Raja Ghosh; Geoff Hale; Yves Durocher; Paul Gatt
Source:
Journal of chromatography 2022 v.1667 pp. 462881
ISSN:
0021-9673
Subject:
mammals,   etc   ; cell culture; chromatography; hydroxyapatite; monoclonal antibodies;     Show all 5 Subjects
Abstract:
... We describe and discuss a simple dry-compression technique for preparing a flat cuboid chromatography device containing a shallow packed-bed of crystalline hydroxyapatite nanoparticles. We then discuss the use of this device for fast protein separation in the bind-and-elute mode. Such separation could be carried out at quite low pressures, making it possible to use inexpensive low pressure chromat ...
DOI:
10.1016/j.chroma.2022.462881

6. How Cells Deal with the Fluctuating Environment: Autophagy Regulation under Stress in Yeast and Mammalian Systems

Author:
Yuchen Lei; Yuxiang Huang; Xin Wen; Zhangyuan Yin; Zhihai Zhang; Daniel J. Klionsky
Source:
Antioxidants 2022 v.11 no.2 pp. -
ISSN:
2076-3921
Subject:
mammals,   etc   ; autophagy; energy; homeostasis; organelles; oxygen; yeasts;     Show all 7 Subjects
Abstract:
... Eukaryotic cells frequently experience fluctuations of the external and internal environments, such as changes in nutrient, energy and oxygen sources, and protein folding status, which, after reaching a particular threshold, become a type of stress. Cells develop several ways to deal with these various types of stress to maintain homeostasis and survival. Among the cellular survival mechanisms, au ...
DOI:
10.3390/antiox11020304

7. Intracellular gold nanoparticles influence light scattering and facilitate amplified spontaneous emission generation

Author:
Phattadon Yajan; Nursidik Yulianto; Matthias Saba; Agus Budi Dharmawan; Mauro Sousa de Almeida; Patricia Taladriz-Blanco; Hutomo Suryo Wasisto; Barbara Rothen-Rutishauser; Alke Petri-Fink; Dedy Septiadi
Source:
Journal of colloid and interface science 2022 v.622 pp. 914-923
ISSN:
0021-9797
Subject:
mammals,   etc   ; bioimaging; epithelium; fluorescence; macrophages; nanogold; rhodamines;     Show all 7 Subjects
Abstract:
... Generation of amplified stimulated emission inside mammalian cells has paved the way for a novel bioimaging and cell sensing approach. Single cells carrying gain media (e.g., fluorescent molecules) are placed inside an optical cavity, allowing the production of intracellular laser emission upon sufficient optical pumping. Here, we investigate the possibility to trigger another amplified emission p ...
DOI:
10.1016/j.jcis.2022.04.149

8. Metal sequestration by S100 proteins in chemically diverse environments

Author:
Tomer Rosen; Kwo-Kwang A. Wang; Elizabeth M. Nolan
Source:
Trends in microbiology 2022 v.30 no.7 pp. 654-664
ISSN:
0966-842X
Subject:
mammals,   etc   ; antimicrobial properties; extracellular space; innate immunity;     Show all 4 Subjects
Abstract:
... During infection, the mammalian host initiates a metal-withholding response against invading microbial pathogens to inhibit their growth and survival, a process often termed ‘nutritional immunity’. The host-defense S100 proteins calprotectin (CP) (S100A8/S100A9 oligomer), S100A12, and S100A7 play key roles in the innate immune response by sequestrating essential transition metal nutrients from mic ...
DOI:
10.1016/j.tim.2021.12.006

9. Naming of new natural products: Standard, pitfalls and tips-and-tricks

Author:
Christian Bailly
Source:
Phytochemistry 2022 v.200 pp. 113250
ISSN:
0031-9422
Subject:
mammals,   etc   ; aquatic organisms; music; plant biochemistry; terminology;     Show all 5 Subjects
Abstract:
... Naming a newly discovered natural product (NP) is a pleasant but difficult exercise. In most cases, the NP name will be given with reference to the species of origin, be it a plant, a marine organism, a mammalian or microbial species. For a long time, the use of biologically-based trivial names has been recommended to identify the parental linkage between the product and the originating genus or s ...
DOI:
10.1016/j.phytochem.2022.113250

10. Predation of the critically endangered Fijian crested iguana (Brachylophus vitiensis) by the swamp harrier (Circus approximans)

Author:
Peter S. Harlow; Pita Biciloa; Jennifer E. Taylor
Source:
Austral ecology 2022 v.47 no.3 pp. 713-716
ISSN:
1442-9985
Subject:
mammals,   etc   ; Brachylophus; Circus; lizards; predation; swamps; Fiji;     Show all 7 Subjects
Abstract:
... The Fijian crested iguana (Brachylophus vitiensis) is the largest extant lizard in Fiji, where it enjoys life in the absence of any mammalian predators. On the only island where this iguana is abundant, the only predator appears to be the swamp harrier (Circus approximans), which is non‐selective in its iguana prey, catching individuals in a similar proportion to their size availability. Here we r ...
DOI:
10.1111/aec.13152

11. Scale and representation of landscapes in mammal studies in Brazil

Author:
Tainá Oliveira Assis; Nilton Carlos Cáceres; Marcelo Passamani; Silvana Amaral
Source:
Acta oecologica 2022 v.114 pp. 103817
ISSN:
1146-609X
Subject:
mammals,   etc   ; habitats; landscape ecology; landscapes; paper; Brazil;     Show all 6 Subjects
Abstract:
... When studying landscapes, defining the scale implies gains and losses of information associated with the choices of resolution and extent needed to understand a given phenomenon. Whereas the local scale is able to provide a more accurate understanding of local dynamics, the global scale able to provide a broader understanding of regional dynamics, yet is more susceptible to suppressing certain loc ...
DOI:
10.1016/j.actao.2022.103817

12. Significance of lncRNA abundance to function

Author:
Ioannis Grammatikakis; Ashish Lal
Source:
Mammalian genome 2022 v.33 no.2 pp. 271-280
ISSN:
0938-8990
Subject:
mammals,   etc   ; cell cycle; gene expression; genome; homeostasis;     Show all 5 Subjects
Abstract:
... Long noncoding RNAs (lncRNAs) have emerged as regulators of diverse cellular processes. Although the vast majority of lncRNAs are expressed at lower levels compared to messenger RNAs (mRNAs), many lncRNAs play a central role in the regulation of cellular homeostasis and gene expression. With the advancement of next generation sequencing technologies, recent studies illustrate the diversity of lncR ...
DOI:
10.1007/s00335-021-09901-4

13. Synthetic gene circuits as tools for drug discovery

Author:
Adam M. Beitz; Conrad G. Oakes; Kate E. Galloway
Source:
Trends in biotechnology 2022 v.40 no.2 pp. 210-225
ISSN:
0167-7799
Subject:
mammals,   etc   ; biotechnology; drugs; organoids; synthetic genes; therapeutics;     Show all 6 Subjects
Abstract:
... Within mammalian systems, there exists enormous opportunity to use synthetic gene circuits to enhance phenotype-based drug discovery, to map the molecular origins of disease, and to validate therapeutics in complex cellular systems. While drug discovery has relied on marker staining and high-content imaging in cell-based assays, synthetic gene circuits expand the potential for precision and speed. ...
DOI:
10.1016/j.tibtech.2021.06.007

14. A sensitive and simple HPLC-FLD-based method for the measurement of intracellular glucose uptake

Author:
Lele Yang; Sijia Wu; Jinchao Wei; Jiagang Deng; Xiaotao Hou; Erwei Hao; Lei Zhang; Peng Li
Source:
Food chemistry 2022 v.372 pp. 131218
ISSN:
0308-8146
Subject:
mammals,   etc   ; energy; fluorescence; food chemistry; glucose; hepatocytes; myoblasts;     Show all 7 Subjects
Abstract:
... Glucose is a primary source of energy used in most organisms. Thus, development of reliable approaches to measure intracellular glucose uptake is an important research issue. 2-[N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) amino]-2-deoxy-d-glucose (2-NBDG), as a fluorescent glucose derivative, has been widely used to track intracellular glucose uptake by fluorescence imaging and measuring in mammalian ce ...
DOI:
10.1016/j.foodchem.2021.131218

15. Evolved DNA Duplex Readers for Strand-Asymmetrically Modified 5-Hydroxymethylcytosine/5-Methylcytosine CpG Dyads

Author:
Benjamin C. Buchmuller; Jessica Dröden; Himanshu Singh; Shubhendu Palei; Malte Drescher; Rasmus Linser; Daniel Summerer
Source:
Journal of the American Chemical Society 2022 v.144 no.7 pp. 2987-2993
ISSN:
1520-5126
Subject:
mammals,   etc   ; 5-methylcytosine; DNA; bacteria; chromatin; epigenetics; mutants;     Show all 7 Subjects
Abstract:
... 5-Methylcytosine (mC) and 5-hydroxymethylcytosine (hmC), the two main epigenetic modifications of mammalian DNA, exist in symmetric and asymmetric combinations in the two strands of CpG dyads. However, revealing such combinations in single DNA duplexes is a significant challenge. Here, we evolve methyl-CpG-binding domains (MBDs) derived from MeCP2 by bacterial cell surface display, resulting in th ...
DOI:
10.1021/jacs.1c10678

16. Orai1α, but not Orai1β, co-localizes with TRPC1 and is required for its plasma membrane location and activation in HeLa cells

Author:
Jose Sanchez-Collado; Jose J. Lopez; Isaac Jardin; Alejandro Berna-Erro; Pedro J. Camello; Carlos Cantonero; Tarik Smani; Gines M. Salido; Juan A. Rosado
Source:
Cellular and molecular life sciences 2022 v.79 no.1 pp. 33
ISSN:
1420-682X
Subject:
mammals,   etc   ; agonists; calcium; fluorescence; plasma membrane; precipitin tests;     Show all 6 Subjects
Abstract:
... The identification of two variants of the canonical pore-forming subunit of the Ca²⁺ release-activated Ca²⁺ (CRAC) channel Orai1, Orai1α and Orai1β, in mammalian cells arises the question whether they exhibit different functional characteristics. Orai1α and Orai1β differ in the N-terminal 63 amino acids, exclusive of Orai1α, and show different sensitivities to Ca²⁺-dependent inactivation, as well ...
DOI:
10.1007/s00018-021-04098-w

17. Regulation of IFNα-induced expression of the short ACE2 isoform by ULK1

Author:
Ricardo E. Perez; Diana Saleiro; Liliana Ilut; Gary E. Schiltz; Frank Eckerdt; Eleanor N. Fish; Leonidas C. Platanias
Source:
Molecular immunology 2022 v.147 pp. 1-9
ISSN:
0161-5890
Subject:
mammals,   etc   ; Severe acute respiratory syndrome coronavirus 2; flavonoids;     Show all 3 Subjects
Abstract:
... The novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been shown to hijack angiotensin converting enzyme 2 (ACE2) for entry into mammalian cells. A short isoform of ACE2, termed deltaACE2 (dACE2), has recently been identified. In contrast to ACE2, the short dACE2 isoform lacks the ability to bind the spike protein of SARS-CoV-2. Several studies have proposed that ...
DOI:
10.1016/j.molimm.2022.04.008

18. Statistical experimental designs to optimize the transient transfection of HEK 293T cells and determine a transfer criterion from adherent cells to larger-scale cell suspension cultures

Author:
Gregor Dekevic; Lars Tasto; Peter Czermak; Denise Salzig
Source:
Journal of biotechnology 2022 v.346 pp. 23-34
ISSN:
0168-1656
Subject:
mammals,   etc   ; biotechnology; cell viability; manufacturing; plasmids; polyethyleneimine; transfection;     Show all 7 Subjects
Abstract:
... The transient transfection of mammalian cells is a rapid and versatile platform for the manufacture of recombinant proteins, but industrial processes depend on reliable scalability and efficient conversion from adherent to suspension cell cultures. Here we describe the optimized transfection of HEK 293T cells in both culture formats. DMEM was the best transfection medium for adherent HEK 293T cell ...
DOI:
10.1016/j.jbiotec.2022.01.004

19. The value of updating GenBank accessions for supermatrix phylogeny: The case of the New Guinean marsupial carnivore genus Myoictis

Author:
Matthew J. Phillips; Michael Westerman; Manuela Cascini
Source:
Molecular phylogenetics and evolution 2022 v.166 pp. 107328
ISSN:
1055-7903
Subject:
mammals,   etc   ; Dasyuridae; carnivores; mitochondria; phylogeny; topology; New Guinea;     Show all 7 Subjects
Abstract:
... Erroneous taxonomic attributions in GenBank accessions can mislead phylogenetic inference and appear to be widespread within genera. We investigate the influence of taxonomic misattributions for reconstructing the phylogeny of three-striped dasyures, which include four recognized Myoictis species (Marsupialia: Dasyuridae) that are distributed across New Guinea and nearby islands. Molecular phyloge ...
DOI:
10.1016/j.ympev.2021.107328

20. Membrane targeting enhances muramyl dipeptide binding to NOD2 and Arf6–GTPase in mammalian cells

Author:
Charles W. Hespen; Xiaohui Zhao; Howard C. Hang
Source:
Chemical communications 2022 v.58 no.46 pp. 6598-6601
ISSN:
1364-548X
Subject:
mammals,   etc   ; dipeptides; intracellular signaling peptides and proteins; mutation; myristoylation;     Show all 5 Subjects
Abstract:
... To further understand the mechanisms of muramyl dipeptide (MDP) sensing by NOD2, we evaluated key properties involved in the formation of the Arf6–MDP–NOD2 complex in mammalian cells. We found that the conserved Arf aromatic triad is crucial for binding to MDP–NOD2. Mutation of Arf6 N-myristoylation and NOD2 S-palmitoylation also abrogated the formation of the Arf6–MDP–NOD2 complex. Notably, lipid ...
DOI:
10.1039/d2cc01903e