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1. One step DNA amplification of mammalian cells in picoliter microwell arrays

Author:
Liu, Wenwen; Li, Zhao; Liu, Yuanjie; Wei, Qingquan; Liu, Yong; Ren, Lufeng; Wang, Chenyu; Yu, Yude
Source:
RSC advances 2019 v.9 no.5 pp. 2865-2869
ISSN:
2046-2069
Subject:
mammals,   etc   ; DNA; silica;     Show all 3 Subjects
Abstract:
... We developed a strategy for direct DNA amplification of single cells on a PEG-modified silica chip with 30 600 picoliter-sized microwells. HPV-positive cells in heterogeneous populations were successfully detected with high accuracy sensitivity as high as single copy. ...
DOI:
10.1039/c8ra06717a

2. Controlling proteolysis of Clp peptidase: a possible target for combating mitochondrial diseases

Author:
da Silva, Ronivaldo Rodrigues
Source:
The international journal of biochemistry & cell biology 2019 v.110 pp. 140-142
ISSN:
1357-2725
Subject:
mammals,   etc   ; apoptosis; mitochondria; peptidases; proteolysis;     Show all 5 Subjects
Abstract:
... Some mechanisms of cellular stress, aging, and apoptosis are related to proteolysis. With respect to ClpP, little is known about the mechanical manner in which the substrate is hydrolyzed in and released from the degradation chamber. Furthermore, what would be the real influence of ClpP in mammalian UPRmt? ...
DOI:
10.1016/j.biocel.2019.03.007

3. Species delimitation in mammals: A response to Gippoliti

Author:
Zachos, Frank E.
Source:
Mammalian biology = 2019 v.94 pp. 132-133
ISSN:
1616-5047
Subject:
mammals,   etc   ; evolution; taxonomy; wildlife management;     Show all 4 Subjects
Abstract:
... In a comment published in this issue, Spartaco Gippoliti (2019) presents a critique of a recent perspective paper of mine (Zachos, 2018a). Specifically, he accuses me of diminishing taxonomy and of denying it its proper role in conservation biology. Here I respond to these criticisms and argue that taxonomy is necessary but not sufficient for delineating appropriate units for conservation due to i ...
DOI:
10.1016/j.mambio.2018.05.008

4. RNA nanostructures and scaffolds for biotechnology applications

Author:
Ohno, Hirohisa; Akamine, Sae; Saito, Hirohide
Source:
Current opinion in biotechnology 2019 v.58 pp. 53-61
ISSN:
0958-1669
Subject:
mammals,   etc   ; RNA; bioengineering; biotechnology; medicine; nanomaterials; proteins;     Show all 7 Subjects
Abstract:
... RNA plays important roles in the regulation of gene expressions and other cellular functions. It functions as both as an informational carrier and a nanomachine due to its complementary base-pairing ability and complexed three-dimensional structure. Several nanostructures have been designed and constructed by exploiting these natural RNA properties. In this review, we will introduce the design pri ...
DOI:
10.1016/j.copbio.2018.11.006

5. Phylogenetic Analysis with Improved Parameters Reveals Conservation in lncRNA Structures

Author:
Tavares, Rafael C.A.; Pyle, Anna Marie; Somarowthu, Srinivas
Source:
Journal of molecular biology 2019 v.431 no.8 pp. 1592-1603
ISSN:
0022-2836
Subject:
mammals,   etc   ; RNA; phylogeny; prediction; sequence alignment;     Show all 5 Subjects
Abstract:
... The existence of evolutionary conservation in base pairing is strong evidence for functional elements of RNA structure, although available tools for rigorous identification of structural conservation are limited. R-scape is a recently developed program for statistical prediction of pairwise covariation from sequence alignments, but it initially showed limited utility on long RNAs, especially those ...
DOI:
10.1016/j.jmb.2019.03.012

6. Hybrid breath figure method: A new insight in Petri dishes for cell culture

Author:
Huang, Chuixiu; Shen, Xiantao; Liu, Xiaojie; Chen, Zhiliang; Shu, Baolian; Wan, Libin; Liu, Huajing; He, Jun
Source:
Journal of colloid and interface science 2019 v.541 pp. 114-122
ISSN:
0021-9797
Subject:
mammals,   etc   ; antibacterial properties; antibiotics; bacteria; cell culture;     Show all 5 Subjects
Abstract:
... The traditional Petri dish, which has not been changed in almost 60 years, has clear limitations when it is applied to cell cultures in a modern biological laboratory. In this work, by integrating the advantages of both the semidirect breath figure (sDBF) method and the traditional breath figure (BF) method, we proposed for the first time a novel hybrid BF method for the fabrication of honeycomb-p ...
DOI:
10.1016/j.jcis.2019.01.074

7. Alternate Grassy Ecosystem States Are Determined by Palatability–Flammability Trade-Offs

Author:
Hempson, Gareth P.; Archibald, Sally; Donaldson, Jason E.; Lehmann, Caroline E.R.
Source:
Trends in ecology & evolution 2019 v.34 no.4 pp. 286-290
ISSN:
0169-5347
Subject:
mammals,   etc   ; ecosystems; grasses; grasslands; grazing; savannas;     Show all 6 Subjects
Abstract:
... Fire and mammalian grazers both consume grasses, and feedbacks between grass species, their functional traits, and consumers have profound effects on grassy ecosystem structure worldwide, such that savanna and grassland states determined by fire or grazing can be considered alternate states. These parallel savanna–forest alternate states, which likewise have myriad cascading ecosystem impacts. ...
DOI:
10.1016/j.tree.2019.01.007

8. Trends and perspectives on the use of animal social network analysis in behavioural ecology: a bibliometric approach

Author:
Webber, Quinn M.R.; Vander Wal, Eric
Source:
Animal behaviour 2019 v.149 pp. 77-87
ISSN:
0003-3472
Subject:
mammals,   etc   ; animal behavior; birds; social networks; students;     Show all 5 Subjects
Abstract:
... The increased popularity and accessibility of social network analysis has improved our ability to test hypotheses about complex animal social structures. To gain a deeper understanding of the use and application of animal social network analysis, we systematically surveyed the literature and extracted information on publication trends from articles using social network analysis. We synthesize tren ...
DOI:
10.1016/j.anbehav.2019.01.010

9. Palaeoenvironmental dynamics in the Cantabrian Region during Greenland stadial 2 approached through pollen and micromammal records: State of the art

Author:
Garcia-Ibaibarriaga, Naroa; Suárez-Bilbao, Aitziber; Iriarte-Chiapusso, María José; Arrizabalaga, Alvaro; Murelaga, Xabier
Source:
Quaternary international 2019 v.506 pp. 14-24
ISSN:
1040-6182
Subject:
small mammals,   etc   ; paleoecology; pollen; sampling; Greenland;     Show all 5 Subjects
Abstract:
... The role of pollen and small mammal records in the palaeoenvironmental reconstruction of the societies that inhabited the Cantabrian Region during Greenland Stadial 2 has gained relevance in the last twenty years. In response to the scarcity of long non-anthropogenic sedimentary sequences that cover the entire Greenland Stadial 2 (with the exception of the beginning of the Late Glacial period), mo ...
DOI:
10.1016/j.quaint.2018.12.004

10. Molecular engineering strategies and methods for the expression and purification of IgG1-based bispecific bivalent antibodies

Author:
Dimasi, N.; Fleming, R.; Wu, H.; Gao, C.
Source:
Methods 2019 v.154 pp. 77-86
ISSN:
1046-2023
Subject:
mammals,   etc   ; antibodies; engineering; inflammation; neoplasms; therapeutics;     Show all 6 Subjects
Abstract:
... In recent years, bispecific antibodies (BisAbs) have emerged as novel pharmaceutical candidates owing to their ability to engage two disease mediators simultaneously, thus providing a possible alternative therapeutic approach in complex diseases such as cancer and inflammation. Here we provide an overview of the molecular design, recombinant expression in mammalian cells and purification of BisAbs ...
DOI:
10.1016/j.ymeth.2018.08.004

11. Correction to: getting fat or getting help? how female mammals cope with energetic constraints on reproduction

Author:
Heldstab, Sandra A.; van Schaik, Carel P.; Isler, Karin
Source:
Frontiers in zoology 2018 v.15 no.1 pp. 3
ISSN:
1742-9994
Subject:
mammals,   etc   ; females; reproduction;     Show all 3 Subjects
Abstract:
... CORRECTION: Unfortunately, upon publication of this article [1] it was noticed there was an error within the Discussion section. During proofing a request to edit the following paragraph was missed: ...
DOI:
10.1186/s12983-017-0236-7

12. With a little help from her friends (and family) part II: Non-maternal caregiving behavior and physiology in mammals

Author:
Rosenbaum, Stacy; Gettler, Lee T.
Source:
Physiology & behavior 2018 v.193 pp. 12-24
ISSN:
0031-9384
Subject:
mammals,   etc   ; physiology; surveys;     Show all 3 Subjects
Abstract:
... The diversity of competing frameworks for explaining the evolution of non-maternal care in mammals (Part I, this issue) reflects the vast range of behaviors and associated outcomes these theories attempt to subsume. Caretaking comprises a wide variety of behavioral domains, and is mediated by an equally large range of physiological systems. In Part II, we provide an overview of how non-maternal ca ...
DOI:
10.1016/j.physbeh.2017.12.027

13. Self-Digestion for Lifespan Extension: Enhanced Autophagy Delays Aging

Author:
Arensman, Michael D.; Eng, Christina H.
Source:
Molecular cell 2018 v.71 no.4 pp. 485-486
ISSN:
1097-2765
Subject:
mammals,   etc   ; autophagy; longevity; mutation;     Show all 4 Subjects
Abstract:
... By systemically boosting autophagy with a knockin mutation that prevents binding of beclin 1 to BCL2, Fernández et al. (2018) demonstrate that enhanced autophagy prolongs lifespan in mammals. ...
DOI:
10.1016/j.molcel.2018.08.002

14. Mammals and meaningful taxonomic units: the debate about species concepts and conservation

Author:
Zachos, Frank E.
Source:
Mammal review 2018 v.48 no.3 pp. 153-159
ISSN:
0305-1838
Subject:
mammals,   etc   ; phylogeny; taxonomy;     Show all 3 Subjects
Abstract:
... Mammalian taxonomy based on the diagnosability version of the Phylogenetic Species Concept has recently been declared the only sound approach to mammalian classification. In this article, based on the underlying evolutionary ontology of species taxa, I explain the fallacy of these arguments and hold that in a ‘grey area’ after lineage sundering, completely objective species delimitation is impossi ...
DOI:
10.1111/mam.12121

15. 5C-ID: Increased resolution Chromosome-Conformation-Capture-Carbon-Copy with in situ 3C and double alternating primer design

Author:
Kim, Ji Hun; Titus, Katelyn R.; Gong, Wanfeng; Beagan, Jonathan A.; Cao, Zhendong; Phillips-Cremins, Jennifer E.
Source:
Methods 2018 v.142 pp. 39-46
ISSN:
1046-2023
Subject:
mammals,   etc   ; chromatin; genome; topology;     Show all 4 Subjects
Abstract:
... Mammalian genomes are folded in a hierarchy of compartments, topologically associating domains (TADs), subTADs, and looping interactions. Currently, there is a great need to evaluate the link between chromatin topology and genome function across many biological conditions and genetic perturbations. Hi-C can generate genome-wide maps of looping interactions but is intractable for high-throughput co ...
DOI:
10.1016/j.ymeth.2018.05.005

16. Chemical strategies to unravel bacterial–eukaryotic signaling

Author:
Gregor, R.; David, S.; Meijler, M. M.
Source:
Chemical Society reviews 2018 v.47 no.5 pp. 1761-1772
ISSN:
1460-4744
Subject:
mammals,   etc   ; bacteria; protein composition;     Show all 3 Subjects
Abstract:
... The common language of bacteria and higher life forms is a lexicon of small molecules that the research community is only beginning to decipher. While many new signaling molecules have been discovered in recent years, the identification of their targets is mostly lagging. This review will focus on the latest chemical-probe based research aimed at understanding how bacteria interact chemically with ...
DOI:
10.1039/c7cs00606c

17. Prostaglandins in teleost ovulation: A review of the roles with a view to comparison with prostaglandins in mammalian ovulation

Author:
Takahashi, Takayuki; Hagiwara, Akane; Ogiwara, Katsueki
Source:
Molecular and cellular endocrinology 2018 v.461 pp. 236-247
ISSN:
0303-7207
Subject:
mammals,   etc   ; oocytes; ovulation; prostaglandins;     Show all 4 Subjects
Abstract:
... Prostaglandins are well known to be central regulators of vertebrate ovulation. Studies addressing the role of prostaglandins in mammalian ovulation have established that they are involved in the processes of oocyte maturation and cumulus oocyte complex expansion. In contrast, despite the first indication of the role of prostaglandins in teleost ovulation appearing 40 years ago, the mechanistic ba ...
DOI:
10.1016/j.mce.2017.09.019

18. Reprogramming the brain with synthetic neurobiology

Author:
Gardner, Elizabeth; Ellington, Andrew
Source:
Current opinion in biotechnology 2019 v.58 pp. 37-44
ISSN:
0958-1669
Subject:
mammals,   etc   ; brain; electrophysiology; genetic techniques and protocols; microscopy; neurodevelopment; neurophysiology;     Show all 7 Subjects
Abstract:
... The mammalian brain is among the most complex organs known in biology. Historically, neuroscience techniques have consisted primarily of low-throughput microscopy and electrophysiological approaches. While these methods will continue to serve the community, the emerging field of synthetic neurobiology may be better equipped to scale with systems neuroscience. By using genetic techniques to achieve ...
DOI:
10.1016/j.copbio.2018.10.013

19. Areas of endemism: to overlap or not to overlap, that is the question

Author:
Szumik, Claudia; Pereyra, Verónica V.; Casagranda, M. Dolores
Source:
Cladistics 2019 v.35 no.2 pp. 198-229
ISSN:
0748-3007
Subject:
mammals,   etc   ; data collection; indigenous species; phylogeny; North America;     Show all 5 Subjects
Abstract:
... The concept of “areas of endemism”, and the assumption that these patterns are always a consequence of vicariant events, are reviewed. This assumption is related to the idea that areas of endemism have well‐defined limits and never share any surface with other areas of endemism because they must represent sister areas supported by sister taxa. Based on this idea, overlapping areas have been consid ...
DOI:
10.1111/cla.12343

20. Rapid Identification of Biofilms Using a Robust Multichannel Polymer Sensor Array

Author:
Ngernpimai, Sawinee; Geng, Yingying; Makabenta, Jessa Marie; Landis, Ryan F.; Keshri, Puspam; Gupta, Akash; Li, Cheng-Hsuan; Chompoosor, Apiwat; Rotello, Vincent M.
Source:
ACS applied materials & interfaces 2019 v.11 no.12 pp. 11202-11208
ISSN:
1944-8252
Subject:
mammals,   etc   ; bacteria; biofilm; coculture; fluorescence; fluorescent dyes; models; polymers;     Show all 8 Subjects
Abstract:
... Infections caused by bacterial biofilms are challenging to diagnose because of the complexity of both the bacteria and the heterogeneous biofilm matrix. We report here a robust polymer-based sensor array that uses selective interactions between polymer sensor elements and the biofilm matrix to identify bacteria species. In this array, an appropriate choice of fluorophore enabled excimer formation ...
DOI:
10.1021/acsami.9b00839