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1. Comparison of miRNA profiles in milk-derived extracellular vesicles and bovine mammary glands

Author:
Wenqing Li; Wanli Li; Xiaoyang Wang; Honglu Zhang; Linfeng Wang; Tengyun Gao
Source:
International dairy journal 2022 v.134 pp. 105444
ISSN:
0958-6946
Subject:
mammary glands,   etc   ; cattle; lactation; microRNA; milk;     Show all 5 Subjects
Abstract:
... Although the role of milk extracellular vesicle (EV)-derived microRNAs (miRNAs) is attracting increasing attention, little is known about the relationship between miRNAs in milk EVs and bovine mammary glands. Therefore, we investigated the miRNA profile in milk EVs and bovine mammary glands at three lactation stages (60 d, 120 d, 240 d) using small RNA sequencing. A total of 70 universally highly ...
DOI:
10.1016/j.idairyj.2022.105444

2. A retrospective on claims regarding clinical mastitis in the subsequent lactation, after use of an internal teat sealant in the dry period

Author:
J Eric Hillerton; Elizabeth A Berry
Source:
Journal of dairy research 2022 v.89 no.2 pp. 173-177
ISSN:
1469-7629
Subject:
mammary glands,   etc   ; dairy cows; ingredients; lactation; pathogens; research; sealants; teat sealants;     Show all 8 Subjects
Abstract:
... Infusion of an internal teat sealant into the mammary gland of the dairy cow at drying off has been claimed to reduce the incidence of clinical mastitis over many months in the subsequent lactation, despite the absence of any ingredient of the sealant remaining for that long. However, these claims have been poorly substantiated, often by lack of identification on when the infection occurred in the ...
DOI:
10.1017/S0022029922000401

3. Solid Carcinoma of the Canine Mammary Gland: a Histological Type or Tumour Cell Arrangement?

Author:
Karen YR. Nakagaki; Maíra M. Nunes; Ana Paula V Garcia; Fernanda C. Nunes; Fernando Schmitt; Geovanni D. Cassali
Source:
Journal of comparative pathology 2022 v.190 pp. 1-12
ISSN:
0021-9975
Subject:
mammary glands,   etc   ; breast neoplasms; carcinoma; dogs; females; immunohistochemistry; metastasis; neoplasm cells; Brazil;     Show all 9 Subjects
Abstract:
... Mammary neoplasms are the most frequently diagnosed tumours in female dogs and are classified into various histological types, including solid carcinomas. We proposed a subclassification of solid carcinomas based on morphological and immunohistochemical characteristics, and correlated the subtypes with prognostic factors. A total of 135 cases of solid mammary carcinoma were selected from 3,400 can ...
DOI:
10.1016/j.jcpa.2021.10.011

4. Relationship between the Composition of Lipids in Forages and the Concentration of Conjugated Linoleic Acid in Cow’s Milk: A Review

Author:
Isabel Cristina Acosta Balcazar; Lorenzo Danilo Granados Rivera; Jaime Salinas Chavira; Benigno Estrada Drouaillet; Miguel Ruiz Albarrán; Yuridia Bautista Martínez
Source:
Animals 2022 v.12 no.13 pp. -
ISSN:
2076-2615
Subject:
mammary glands,   etc   ; biohydrogenation; conjugated linoleic acid; cows; diabetes; milk; nitrogen; nutritive value; obesity; regrowth;     Show all 10 Subjects
Abstract:
... Conjugated linoleic acid (CLA), has been shown to have protective effects against various diseases, such as obesity, arteriosclerosis, diabetes, chronic inflammatory diseases, and cancer. This fatty acid in ruminants results from two processes, biohydrogenation, which takes place in the rumen, and de novo synthesis, carried out in the mammary gland, and it has linoleic and α-linolenic acids as its ...
DOI:
10.3390/ani12131621

5. Inflammatory Response of Primary Cultured Bovine Mammary Epithelial Cells to Staphylococcus aureus Extracellular Vesicles

Author:
Mara D. Saenz-de-Juano; Giulia Silvestrelli; Andres Weber; Christian Röhrig; Mathias Schmelcher; Susanne E. Ulbrich
Source:
Biology 2022 v.11 no.3 pp. -
ISSN:
2079-7737
Subject:
mammary glands,   etc   ; Staphylococcus aureus; cytotoxicity; epithelium; gene expression; inflammation; pathogenesis; tumor necrosis factor-alpha;     Show all 8 Subjects
Abstract:
... In dairy cows, Staphylococcus aureus (S. aureus) is among the most prevalent microorganisms worldwide, causing mastitis, an inflammation of the mammary gland. Production of extracellular vesicles (EVs) is a common feature of S. aureus strains, which contributes to its pathogenesis by delivering bacterial effector molecules to host cells. In the current study, we evaluated the differences between f ...
DOI:
10.3390/biology11030415

6. Data on mammary gland microRNAs expression, their predicted gene targets and corresponding pathway analysis in female mice receiving flaxseed or its oil and secoisolariciresinol diglucoside components

Author:
Diana Wu; Amel Taibi; Zhen Lin; Lilian U. Thompson; Elena M. Comelli
Source:
Data in Brief 2022 v.42 pp. 108328
ISSN:
2352-3409
Subject:
mammary glands,   etc   ; biomarkers; breast neoplasms; carcinogenesis; databases; diet; females; gene expression; genes; linseed; microRNA; oils;     Show all 12 Subjects
Abstract:
... Dietary flaxseed may act via microRNAs (miRNAs) to affect the health of the mammary gland. These data are in support of the article entitled “Effects of flaxseed and its components on mammary gland miRNome: identification of potential biomarkers to prevent breast cancer development” [1]. Here, we provide miRNA expression data obtained from NanoString nCounter® profiling of mammary gland RNA from C ...
DOI:
10.1016/j.dib.2022.108328

7. Evaluation of the tRNA-Leu (UUR) gene haplotype profile observed in canine mammary gland tumours based on comparative analysis with the MT-TL1 human gene

Author:
Krzysztof Kowal; Angelika Tkaczyk-Wlizło; Mariusz Pierzchała; Brygida Ślaska
Source:
Annals of animal science 2022 v.22 no.3 pp. 915-922
ISSN:
2300-8733
Subject:
mammary glands,   etc   ; acidosis; animal science; blood; carcinogenesis; dogs; etiology; genes; haplotypes; humans; mitochondria; mitochondrial DNA;     Show all 12 Subjects
Abstract:
... The aetiology and pathogenesis of many canine tumours are likely to be similar to cancers found in humans. This study aimed to evaluate a plausible link between changes in the tRNA-Leu (UUR) gene and the carcinogenesis process in dogs with mammary gland tumours. The whole mitochondrial DNA (mtDNA) isolated from blood and tumour tissues of 13 dogs with malignant mammary gland tumours was sequenced. ...
DOI:
10.2478/aoas-2022-0009

8. Intraductal delivery and x-ray visualization of ethanol-based ablative solution for prevention and local treatment of breast cancer in mouse models

Author:
Kenyon Elizabeth; Zaluzec Erin K.; Powell Katherine; Volk Maximilian; Chakravarty Shatadru; Hix Jeremy; Arora Ripla; Westerhuis Jennifer J.; Kiupel Matti; Shapiro Erik M.; Sempere Lorenzo F.
Source:
Journal of visualized experiments 2022 no.182 pp. e63457
ISSN:
1940-087X
Subject:
mammary glands,   etc   ; X-radiation; breast neoplasms; breasts; cytotoxicity; death; epithelium; ethanol; genetic engineering; humans; mice; surgery;     Show all 12 Subjects
Abstract:
... Breast cancer is the most prevalent cancer and the second-leading cause of cancer-related death for women in the USA. For high-risk women, prophylactic mastectomy is the most effective primary prevention strategy. Prophylactic mastectomy is an aggressive surgical procedure that completely removes the mammary epithelial cells from which breast cancer arises along with the surrounding tissue. We see ...
DOI:
10.3791/63457

9. Longitudinal intravital imaging through clear silicone windows

Author:
Maiorino Laura; Shevik Margaret; Adrover José M.; Han Xiao; Georgas Elias; Wilkinson John Erby; Seidner Harrison; Foerschner Leonie; Tuveson David A.; Qin Yi-Xian; Egeblad Mikala
Source:
Journal of visualized experiments 2022 no.179 pp. e62757
ISSN:
1940-087X
Subject:
mammary glands,   etc   ; cell movement; death; durability; euthanasia; films (materials); glass; inflammation; mice; microscopy; polydimethylsiloxane; stainless steel;     Show all 12 Subjects
Abstract:
... Intravital microscopy (IVM) enables visualization of cell movement, division, and death at single-cell resolution. IVM through surgically inserted imaging windows is particularly powerful because it allows longitudinal observation of the same tissue over days to weeks. Typical imaging windows comprise a glass coverslip in a biocompatible metal frame sutured to the mouse’s skin. These windows can i ...
DOI:
10.3791/62757

10. Potential nutraceuticals from the casein fraction of goat’s milk

Author:
Shruti Dhasmana; Sanjita Das; Shivani Shrivastava
Source:
Journal of food biochemistry 2022 v.46 no.6 pp. e13982
ISSN:
0145-8884
Subject:
mammary glands,   etc   ; bioreactors; dietary supplements; drugs; goat milk; goats; meat; medicine; milk; nutrient content; peptides; therapeutics;     Show all 12 Subjects
Abstract:
... Goat is one of the major dairy and meat providers. In terms of structure, nutrient content, and medicinal properties, goat milk is somewhat different from other milk. The differences in composition are important in determining the technical suitability of goat milk and its products for health benefits. In recent years, there has been increasing attention to the identification and molecular composi ...
DOI:
10.1111/jfbc.13982

11. Canine mammary gland disease in New Zealand: a review of samples from 797 dogs

Author:
H Ariyarathna; D Aberdein; N Thomson; I Gibson; JS Munday
Source:
New Zealand veterinary journal 2022 v.70 no.2 pp. 95-100
ISSN:
1176-0710
Subject:
mammary glands,   etc   ; adenoma; biopsy; carcinoma; databases; dogs; histology; mammary neoplasms (animal); patients; purebreds; t-test; New Zealand;     Show all 12 Subjects
Abstract:
... To evaluate the proportions of canine mammary gland lesions submitted to a New Zealand diagnostic laboratory, that were neoplastic vs. non-neoplastic and, among neoplasms, malignant vs. benign, and to determine whether age, reproductive status or breed of dog, or size of the mammary mass were associated with the histological diagnosis. Canine mammary gland biopsies submitted between the start of 2 ...
DOI:
10.1080/00480169.2021.2004953

12. Milk fat globules as a source of microRNAs for mastitis detection

Author:
Christine Leroux; Karol Pawlowski; Pierre-Alexis Billa; José A.A. Pires; Yannick Faulconnier
Source:
Livestock science 2022 v.263 pp. 104997
ISSN:
1871-1413
Subject:
mammary glands,   etc   ; animal welfare; apoptosis; bioinformatics; biomarkers; cell cycle; gene expression; inflammation; interleukins; lipopolysaccharides; microRNA; milk fat;     Show all 12 Subjects
Abstract:
... Mastitis is an infectious inflammatory disease in dairy cows, causing economic losses and reducing animal welfare. With the final aim of discovering early and easily accessible biomarkers, the objective of this study was to validate the use of milk fat globules (MFGs) as a source of small non-coding RNAs (microRNAs, miRNAs) to diagnose mastitis. We studied the abundance of six miRNAs known to be r ...
DOI:
10.1016/j.livsci.2022.104997

13. The bovine milk microbiome – an evolving science

Author:
Pamela L. Ruegg
Source:
Domestic animal endocrinology 2022 v.79 pp. 106708
ISSN:
0739-7240
Subject:
mammary glands,   etc   ; DNA; bacterial biomass; cattle; dysbiosis; endocrinology; farms; genome; genomics; keratin; microbiome; milk; sanitation; udders; viability;     Show all 15 Subjects
Abstract:
... Improved access to genome based, culture independent methods has generated great interest in defining the bovine milk microbiome. Several comprehensive reviews of this subject have recently been published and the purpose of this short review is to consolidate current understanding of the relevance and biological significance of this emerging topic. In contrast to mucosal organs that contain rich a ...
DOI:
10.1016/j.domaniend.2021.106708

14. A deep learning algorithm predicts milk yield and production stage of dairy cows utilizing ultrasound echotexture analysis of the mammary gland

Author:
Konstantinos S. Themistokleous; Nikos Sakellariou; Evangelos Kiossis
Source:
Computers and electronics in agriculture 2022 v.198 pp. 106992
ISSN:
0168-1699
Subject:
mammary glands,   etc   ; Holstein; agriculture; algorithms; data collection; electronics; health services; lactation; milk yield; models; udders; ultrasonics; ultrasonography;     Show all 13 Subjects
Abstract:
... For decades now, ultrasonography is being utilized in dairy animals’ udder health care. Recent studies have employed echotexture analysis for the examination of the mammary parenchyma and the investigation of pathological conditions. The present study aimed to investigate whether a deep neural network could predict the cows’ daily milk yield and production stage, utilizing features from echotextur ...
DOI:
10.1016/j.compag.2022.106992

15. Selenium Deficiency Promotes Oxidative Stress-Induced Mastitis via Activating the NF-κB and MAPK Pathways in Dairy Cow

Author:
Yanhe Zhang; Yueqi Xu; Bowen Chen; Bing Zhao; Xue-jiao Gao
Source:
Biological trace element research 2022 v.200 no.6 pp. 2716-2726
ISSN:
0163-4984
Subject:
mammary glands,   etc   ; antioxidants; dairy cows; homeostasis; immunomodulators; inflammation; interleukin-6; oxidative stress; pathogenesis; research; secretion; trace elements;     Show all 12 Subjects
Abstract:
... Selenium (Se) is an antioxidant and immunomodulator that can participate in the control of specific endocrine pathways. Disturbance of redox homeostasis is closely related to the pathogenesis of many diseases. Se is also an important nutrient element for dairy cows. First, oxidative stress (OS) induced by Se deficiency was investigated along with a possible mechanism of its induction of mammary gl ...
DOI:
10.1007/s12011-021-02882-0

16. Molecular characterization of CRBR2 fragment of TLR4 gene in association with mastitis in Vrindavani cattle

Author:
Manjit Panigrahi; Harshit Kumar; Sonali Sonejita Nayak; Divya Rajawat; Subhashree Parida; Bharat Bhushan; Arjava Sharma; Triveni Dutt
Source:
Microbial pathogenesis 2022 v.165 pp. 105483
ISSN:
0882-4010
Subject:
mammary glands,   etc   ; Escherichia coli; alleles; crossbreds; endotoxins; farms; genotype; ligands; lipopolysaccharides; neutrophils; pathogenesis; pathogens; regression analysis; sequence analysis;     Show all 14 Subjects
Abstract:
... The bovine TLR4 gene is an interesting candidate marker for mastitis resistance, since it is involved in neutrophil migration to and from the mammary gland during mastitis. TLR4 detects pathogen ligands, such as the Escherichia coli lipopolysaccharide (LPS) endotoxin and facilitates innate and adaptive immune responses. In the current study, a total of 130 crossbred cows (74 mastitis tolerant and ...
DOI:
10.1016/j.micpath.2022.105483

17. The role of the IGF system in mammary physiology of ruminants

Author:
Wendie S. Cohick
Source:
Domestic animal endocrinology 2022 v.79 pp. 106709
ISSN:
0739-7240
Subject:
mammary glands,   etc   ; autocrine signaling; bioactive properties; cell proliferation; cell viability; genetic engineering; lactation; mammary development; models; morphogenesis; somatotropin;     Show all 11 Subjects
Abstract:
... The IGF system plays a central role in all stages of mammary development, lactation and involution. IGFs exert their effects on the mammary gland through both endocrine and paracrine/autocrine mechanisms and the importance of circulating versus local IGF action remains an open question, especially in ruminants. At the whole organ level, a critical role for IGFs in ductal morphogenesis and lobuloal ...
DOI:
10.1016/j.domaniend.2021.106709

18. Pathways Involved in the Development of Vasculogenic Mimicry in Canine Mammary Carcinoma Cell Cultures

Author:
Giulia G. Guiraldelli; Maria Carolina M. Prado; Patrícia de F Lainetti; Antonio F. Leis-Filho; Priscila E. Kobayashi; Sarah S. Cury; Carlos E. Fonseca-Alves; Renee Laufer-Amorim
Source:
Journal of comparative pathology 2022 v.192 pp. 50-60
ISSN:
0021-9975
Subject:
mammary glands,   etc   ; breast neoplasms; cell lines; dogs; gene expression; gene expression regulation; metastasis; neoplasm cells; nutrition; prognosis; therapeutics;     Show all 11 Subjects
Abstract:
... Vasculogenic mimicry (VM) is the ability of highly aggressive cancer cells to form fluid-conducting channels that facilitate the nutrition and metastasis of cancer cells. Considering the importance of VM in the prognosis of canine mammary gland tumours, this study aimed to investigate global gene expression in two canine mammary carcinoma cell cultures associated with the capacity for VM in vitro. ...
DOI:
10.1016/j.jcpa.2022.01.001

19. Effects of nutrient restriction and subsequent realimentation in pregnant beef cows: Maternal endocrine profile, umbilical hemodynamics, and mammary gland development and hemodynamics

Author:
F.A.C.C. Silva; L.E. Camacho; C.O. Lemley; D.M. Hallford; K.C. Swanson; K.A. Vonnahme
Source:
Theriogenology 2022 v.191 pp. 109-121
ISSN:
0093-691X
Subject:
mammary glands,   etc   ; beef; blood flow; blood serum; dry matter intake; lactation; mammary development; maternal nutrition; pregnancy; repletion; urea nitrogen;     Show all 11 Subjects
Abstract:
... Our hypothesis was that maternal nutrient restriction would negatively impact the endocrine and metabolic status of the pregnant cow, therefore influencing the mammary gland in preparation for lactation. We further hypothesized that earlier timing of realimentation could prevent negative impacts of nutrient restriction. The objectives were to investigate the influence of nutrient restriction and r ...
DOI:
10.1016/j.theriogenology.2022.08.009

20. The adaptation of maternal energy metabolism to lactation and its underlying mechanisms

Author:
Gabriel Forato Anhê; Silvana Bordin
Source:
Molecular and cellular endocrinology 2022 v.553 pp. 111697
ISSN:
0303-7207
Subject:
mammary glands,   etc   ; brown adipose tissue; endocrinology; energy metabolism; lactation; liver; milk; observational studies; pancreas; transcription (genetics); white adipose tissue;     Show all 11 Subjects
Abstract:
... Maternal energy metabolism undergoes a singular adaptation during lactation that allows for the caloric enrichment of milk. Changes in the mammary gland, changes in the white adipose tissue, brown adipose tissue, liver, skeletal muscles and endocrine pancreas are pivotal for this adaptation. The present review details the landmark studies describing the enzymatic modulation and the endocrine signa ...
DOI:
10.1016/j.mce.2022.111697