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1. The effects of feed materials on the nutrient composition of Protaetia brevitarsis larvae

Author:
Jeong, Deokyeol; Min, Namgyong; Kim, Yeongbu; Kim, Soo Rin; Kwon, Ohseok
Source:
Entomological research 2020 v.50 no.1 pp. 23-27
ISSN:
1738-2297
Subject:
medicinal properties,   etc   ; Protaetia; instars; larvae; nutrient content;     Show all 5 Subjects
Abstract:
... To find out the effect of feed materials on the nutrient composition of Protaetia brevitarsis larvae (Pbl), three different feed materials were prepared and fed to the Pbl populations. After the Pbl population reached the third instar stage, they were boiled and dried for the nutrient analysis. The results showed that the nutrient composition of Pbl varied in response to the feed materials. Theref ...
DOI:
10.1111/1748-5967.12404

2. Recent developments towards the synthesis of paroxetine: A 3,4-disubstituted piperidine

Author:
Jana, Samaresh; Sarkar, Sohini; Morris, Scott A.
Source:
Tetrahedron 2020 v.76 no.25 pp. 131215
ISSN:
0040-4020
Subject:
medicinal properties,   etc   ; chemical reactions; chemical structure; piperidines; synthesis;     Show all 5 Subjects
Abstract:
... Paroxetine is a trans-3,4-disubstituted piperidine compound that exhibits important medicinal properties. Over the past few decades, various strategies have been revealed in application to its synthesis. This review will highlight some of the synthetic approaches developed for paroxetine in past ten years. The goal of this review is to showcase recent strategies used to synthesize paroxetine with ...
DOI:
10.1016/j.tet.2020.131215

3. Recent developments concerned with the synthesis of aminocyclitols

Author:
Salamci, Emine
Source:
Tetrahedron letters 2020 v.61 no.15 pp. 151728
ISSN:
0040-4039
Subject:
medicinal properties,   etc   ; chemical reactions; chemical structure; organic compounds;     Show all 4 Subjects
Abstract:
... This review provides a compilation of the most recent synthetic methodologies for assembling aminocyclitols, a group of natural products that has received wide attention in recent years due to their varied medicinal applications. The literature covered in this review dates from January 2013 to December 2019. ...
DOI:
10.1016/j.tetlet.2020.151728

4. Review: Southern African medicinal plants used as blood purifiers

Author:
van Vuuren, S.; Frank, L.
Source:
Journal of ethnopharmacology 2020 v.249 pp. 112434
ISSN:
0378-8741
Subject:
medicinal properties,   etc   ; blood; databases; medicinal plants; traditional medicine; Southern Africa;     Show all 6 Subjects
Abstract:
... Blood purification practices, also referred to as blood cleansing or detoxification, is an ancient concept which is widespread amongst African traditional medicine, but for which no modern scientific basis exists. There prevails considerable ambiguity in defining what a blood purifier is.The purpose of this review is to firstly define what a blood purifier is in the context of African traditional ...
DOI:
10.1016/j.jep.2019.112434

5. Plant Antioxidant for Application in Food and Nutraceutical Industries

Author:
Loizzo, Monica Rosa; Tundis, Rosa
Source:
Antioxidants 2019 v.8 no.10
ISSN:
2076-3921
Subject:
medicinal properties,   etc   ; antioxidants; industry; odors;     Show all 4 Subjects
Abstract:
... Plants have been used since approximately 5000 BC not only for their medicinal properties, but also as food aroma and for their preservative activity [...] ...
DOI:
10.3390/antiox8100453
PubMed:
31590399
PubMed Central:
PMC6826388

6. Nitroketene N,S-acetals: synergistic building blocks for the synthesis of heterocycles

Author:
Saigal,; Khan, Sarfaraz; Rahman, Habibur; Shafiullah,; Khan, Md. Musawwer
Source:
RSC advances 2019 v.9 no.25 pp. 14477-14502
ISSN:
2046-2069
Subject:
medicinal properties,   etc   ; chemistry; heterocyclic compounds;     Show all 3 Subjects
Abstract:
... The development of novel heterocyclic compounds from simple and easily accessible starting components is of significant importance in medicinal chemistry. Due to the presence of active chromophores and potent pharmacological activities, nitroketene N,S-acetals have emerged as a fascinating building block in organic synthesis. The synergistic skeleton of these acetals and the presence of electron-d ...
DOI:
10.1039/c9ra00630c

7. Connaraceae: An updated overview of research and the pharmacological potential of 39 species

Author:
Nunes Alves Paim, Luís Fernando; Patrocínio Toledo, Cássio Augusto; Lima da Paz, Joicelene Regina; Picolotto, Aline; Ballardin, Guilherme; Souza, Vinicius Castro; Salvador, Mirian; Moura, Sidnei
Source:
Journal of ethnopharmacology 2020 v.261 pp. 112980
ISSN:
0378-8741
Subject:
medicinal properties,   etc   ; Agelaea; Rourea; chemical compounds; databases; ethnobotany; indigenous knowledge; medicinal plants; therapeutics; toxicology; traditional medicine;     Show all 11 Subjects
Abstract:
... An interdisciplinary scientific investigation of biologically active agents is fundamental to search for natural substances with therapeutic action. This review collected the most relevant information on traditional knowledge related to the use of plants of the Connaraceae family. This work is the first to compile all the published ethnobotanical, chemical, pharmacological, and toxicological infor ...
DOI:
10.1016/j.jep.2020.112980

8. Eucalyptus honey: Quality parameters, chemical composition and health-promoting properties

Author:
Bobis, Otilia; Moise, Adela Ramona; Ballesteros, Isabel; Reyes, Estefanía Sánchez; Durán, Silvia Sánchez; Sánchez-Sánchez, José; Cruz-Quintana, Sandra; Giampieri, Francesca; Battino, Maurizio; Alvarez-Suarez, José M.
Source:
Food chemistry 2020 v.325 pp. 126870
ISSN:
0308-8146
Subject:
medicinal properties,   etc   ; Eucalyptus; adulterated products; chemical composition; commercialization; honey; microbial contamination; physicochemical properties; pollen; trees;     Show all 10 Subjects
Abstract:
... Eucalyptus honey is an important unifloral honey commercialized worldwide and much desired by consumers due to the medicinal properties attributed to it because of the plant from which it is produced. In general, eucalyptus honey has been classified as being rich in pollen grains from the eucalyptus tree as well as having physicochemical characteristics that, in a way, have made it stand out from ...
DOI:
10.1016/j.foodchem.2020.126870

9. Cationic surfactants based on ferrocene containing thiourea: Synthesis, self-aggregation, and antioxidant properties

Author:
Naz, Mehwish; Ali, Jahangeer; Fatima, Saira; Tabassum, Saira; Nawaz, Sameen; Badshah, Amin; Dou, Hongjing
Source:
Colloids and surfaces 2020 v.597 pp. 124760
ISSN:
0927-7757
Subject:
medicinal properties,   etc   ; antioxidant activity; cationic surfactants; comparative study; cytotoxicity; ferrocenes; micelles; thiourea;     Show all 8 Subjects
Abstract:
... Keeping in view the significance of cationic surfactants in various fields of life since the ancient times, here we are reporting the synthesis of a new ferrocenyl thiourea derivative along with an entirely new series of ferrocene based cationic surfactants in which variable alkyl chain lengths are introduced while keeping the head structure same, thus acting as a key to comparative study of their ...
DOI:
10.1016/j.colsurfa.2020.124760

10. Engineering chimeric diterpene synthases and isoprenoid biosynthetic pathways enables high-level production of miltiradiene in yeast

Author:
Hu, Tianyuan; Zhou, Jiawei; Tong, Yuru; Su, Ping; Li, Xinlin; Liu, Yuan; Liu, Nan; Wu, Xiaoyi; Zhang, Yifeng; Wang, Jiadian; Gao, Linhui; Tu, Lichan; Lu, Yun; Jiang, Zhouqian; Zhou, Yongjin J.; Gao, Wei; Huang, Luqi
Source:
Metabolic engineering 2020 v.60 pp. 87-96
ISSN:
1096-7176
Subject:
medicinal properties,   etc   ; Plectranthus barbatus; Salvia miltiorrhiza; biochemical pathways; bioreactors; biosynthesis; culture flasks; engineering; enzymes; geranylgeraniols; yeasts;     Show all 11 Subjects
Abstract:
... Miltiradiene is a key intermediate in the biosynthesis of many important natural diterpene compounds with significant pharmacological activity, including triptolide, tanshinones, carnosic acid and carnosol. Sufficient accumulation of miltiradiene is vital for the production of these medicinal compounds. In this study, comprehensive engineering strategies were applied to construct a high-yielding m ...
DOI:
10.1016/j.ymben.2020.03.011

11. Extraction, structure and bioactivities of the polysaccharides from Pleurotus eryngii: A review

Author:
Zhang, Bingru; Li, Yanying; Zhang, Fuming; Linhardt, Robert J.; Zeng, Guoyang; Zhang, Anqiang
Source:
International journal of biological macromolecules 2020 v.150 pp. 1342-1347
ISSN:
0141-8130
Subject:
medicinal properties,   etc   ; Pleurotus eryngii; antibacterial properties; antioxidants; immunomodulation; mushrooms; polysaccharides; product development;     Show all 8 Subjects
Abstract:
... Pleurotus eryngii (also known as king trumpet mushroom or king oyster mushroom) is an edible mushroom cultivated widely in many regions of the world. Polysaccharides from P. eryngii have a variety of biological activities, including anti-oxidant, anti-hyperlipidemic, anti-tumor, immunoregulatory and bacteriostatic. This paper reviews the extraction/purification, structural analysis and pharmacolog ...
DOI:
10.1016/j.ijbiomac.2019.10.144

12. Terminalia catappa leaf extract is an effective rearing medium for larviculture of gouramis

Author:
Sung, Yeong Yik; Abol-Munafi, A.B.
Source:
Journal of applied aquaculture 2020 v.32 no.2 pp. 175-185
ISSN:
1545-0805
Subject:
medicinal properties,   etc   ; Chlorella; Paramecium; Terminalia catappa; aquaculture; culture media; fish; larvae; leaf extracts; specific growth rate;     Show all 10 Subjects
Abstract:
... Gouramis require soft and acidic waters for optimal development, and in this context, a cheap and effective culture medium is required. In this study, Pearl and Blue gourami larvae were raised in Terminalia catappa leaf extract (TCE), clear water, and green water, the latter containing 1 × 10⁵ cells/ml Chlorella from Tilapia cultures. Larval survival and specific growth rate (SGR) were determined ...
DOI:
10.1080/10454438.2019.1614509

13. Pharmacokinetic Comparisons of Naringenin and Naringenin-Nicotinamide Cocrystal in Rats by LC-MS/MS

Author:
Xu, Dan; Zhang, Gui-Qiu; Zhang, Ting-Ting; Jin, Bo; Ma, Chen
Source:
Journal of Analytical Methods in Chemistry (Online) 2020 v.2020
ISSN:
2090-8873
Subject:
medicinal properties,   etc   ; absorption; bioavailability; liquid chromatography; mass spectrometry; naringenin; nicotinamide; oral administration; pharmacokinetics; rats; water solubility;     Show all 11 Subjects
Abstract:
... Naringenin (NAR), 4′,5,7-trihydroxydihydroflavone, has a wide range of pharmacological activities but shows poor water solubility and low bioavailability. The pharmacokinetics and bioavailability of naringenin-nicotinamide cocrystal (NAR-NCT), which offers improved solubility, were evaluated in this study. Rats were orally administered NAR, a physical mixture of naringenin and nicotinamide (NAR +  ...
DOI:
10.1155/2020/8364218
PubMed:
32322425
PubMed Central:
PMC7152953

14. Dammarane triterpenoid glycosides in Bacopa monnieri: A review on chemical diversity and bioactivity

Author:
Bhandari, Pamita; Sendri, Nitisha; Devidas, Shinde Bhagatsing
Source:
Phytochemistry 2020 v.172 pp. 112276
ISSN:
0031-9422
Subject:
medicinal properties,   etc   ; Bacopa monnieri; chemical composition; glycosides; medicinal plants; medicine; memory; metabolites; spectroscopy; triterpenoids; India;     Show all 11 Subjects
Abstract:
... Bacopa monnieri (L.) is a reputed medicinal herb in traditional system of medicine of India, where it is used as nervine tonic to sharpen intellect and memory. This review discusses chemical characterization of dammarane triterpenoid glycosides which are well accepted for improvement in memory and for potential pharmacological activities. In addition, this review provides information on the chemic ...
DOI:
10.1016/j.phytochem.2020.112276

15. Total Synthesis of (±)-11-O-Debenzoyltashironin via Palladium-Catalyzed 5-endo Ene-yne Cyclization Enabled trans-5–6 Ring Fusion

Author:
Tong, Jie; Xia, Tianrun; Wang, Bo
Source:
Organic letters 2020 v.22 no.7 pp. 2730-2734
ISSN:
1523-7052
Subject:
medicinal properties,   etc   ; Illicium; carbon; catalytic activity; chemical reactions; chemical structure; palladium; sesquiterpenoids; stereochemistry; stereoselectivity;     Show all 10 Subjects
Abstract:
... Illicium sesquiterpenes are a synthetically fascinating family of polycyclic natural products owing to their diversified pharmacological activities and structural complexity. Our cumulative efforts on developing a universal reductive coupling strategy toward stereoselective assembly of illicium sesquiterpenes recently resulted in a total synthesis of 11-O-debenzoyltashironin, a rare illicium sesqu ...
DOI:
10.1021/acs.orglett.0c00689

16. Direct Enantio- and Diastereoselective Zn-ProPhenol-Catalyzed Mannich Reactions of CF₃- and SCF₃-Substituted Ketones

Author:
Trost, Barry M.; Hung, Chao-I Joey; Mata, Guillaume; Liu, Ying; Lu, Yiye; Gnanamani, Elumalai
Source:
Organic letters 2020 v.22 no.6 pp. 2437-2441
ISSN:
1523-7052
Subject:
medicinal properties,   etc   ; catalytic activity; chemical reactions; chemical structure; diastereoselectivity; drugs; enantioselectivity; ketones;     Show all 8 Subjects
Abstract:
... Enantioselective incorporation of trifluoromethyl (−CF₃) and trifuoromethylthio (−SCF₃) groups in small molecules is of high interest to modulate the potency and pharmacological properties of drug candidates. Herein, we report a Zn-ProPhenol catalyzed diastereo- and enantioselective Mannich addition of α-trifluoromethyl- and α-trifuoromethylthio-substituted ketones. This transformation uses cyclic ...
DOI:
10.1021/acs.orglett.0c00646

17. P-Stereogenic N-Phosphine–Phosphite Ligands for the Rh-Catalyzed Hydrogenation of Olefins

Author:
Biosca, Maria; de la Cruz-Sánchez, Pol; Pàmies, Oscar; Diéguez, Montserrat
Source:
Journal of organic chemistry 2020 v.85 no.7 pp. 4730-4739
ISSN:
1520-6904
Subject:
medicinal properties,   etc   ; active ingredients; alkenes; catalysts; catalytic activity; chemical structure; hydrogenation; ligands; organic chemistry; rhodium;     Show all 10 Subjects
Abstract:
... We have identified a successful family of simple P-stereogenic N-phosphine–phosphite ligands for the Rh-catalyzed asymmetric hydrogenation of olefins. These catalysts show excellent enantiocontrol for α-dehydroamino acid derivatives and α-enamides (ee’s up to >99%) and promising results for the more challenging β-analogues (ee’s up to 80%). The usefulness of these catalytic systems was further dem ...
DOI:
10.1021/acs.joc.9b03508

18. Evaluation of phytochemical and medicinal properties of Moringa (Moringa oleifera) as a potential functional food

Author:
Ma, Z.F.; Ahmad, J.; Zhang, H.; Khan, I.; Muhammad, S.
Source:
South African journal of botany 2020 v.129 pp. 40-46
ISSN:
0254-6299
Subject:
medicinal properties,   etc   ; Moringa oleifera; antioxidant activity; bioactive compounds; flavonoids; functional foods; malnutrition; tropical plants;     Show all 8 Subjects
Abstract:
... Moringa oleifera (Moringa), a perennial deciduous tropical plant belonging to the Moringaceae family, is rich in many bioactive compounds. Moringa is also considered as a remedy to fight malnutrition. It possesses many pharmacological properties such as anti-cancer, anti-diabetic, anti-inflammatory and antioxidant. It is possible that the pharmacological properties of Moringa is closely associated ...
DOI:
10.1016/j.sajb.2018.12.002

19. Kolbe Anodic Decarboxylation as a Green Way To Access 2-Pyrrolidinones

Author:
Quertenmont, Mathilde; Goodall, Iain; Lam, Kevin; Markó, István; Riant, Olivier
Source:
Organic letters 2020 v.22 no.5 pp. 1771-1775
ISSN:
1523-7052
Subject:
medicinal properties,   etc   ; chemical structure; cognition; cross-coupling reactions; cyclization reactions; decarboxylation; electrosynthesis; pharmaceutical industry; pyrrolidones;     Show all 9 Subjects
Abstract:
... Nootropic compounds are a group of pharmacologically active pyrrolidones. These molecules, which enhance cognition properties and possess a large prescription field, are particularly interesting synthetic targets for the pharmaceutical industry. In this Article, we disclose an effective and environmentally friendly pyrrolidinone synthesis using electrosynthesis. The newly developed methodology inc ...
DOI:
10.1021/acs.orglett.0c00056

20. Use of N-oxide and cationic surfactants to enhance antioxidant properties of (+)-usnic acid loaded liposomes

Author:
Battista, Sara; Campitelli, Patrizio; Galantini, Luciano; Köber, Mariana; Vargas-Nadal, Guillem; Ventosa, Nora; Giansanti, Luisa
Source:
Colloids and surfaces 2020 v.585 pp. 124154
ISSN:
0927-7757
Subject:
medicinal properties,   etc   ; antioxidant activity; antioxidants; cationic surfactants; chemical structure; hydrophilicity; hydrophobicity; nitrogen oxides;     Show all 8 Subjects
Abstract:
... The influence of the presence of synthetic structurally related N-oxide and corresponding cationic surfactants with different chain lengths on the properties of 1,2-dimyristoyl-sn-glycero-3-phosphocholine liposomes was investigated. Their potentiality as delivery systems of (+)-usnic acid was also evaluated by studying its entrapment efficiency and its antioxidant activity. In fact, (+)-usnic acid ...
DOI:
10.1016/j.colsurfa.2019.124154