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You searched for: Subject "medicinal properties" Remove constraint Subject: "medicinal properties"
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1. Glycyrrhizinic acid in licorice products on the Danish market

Author:
Nicolai Z. Ballin; Dorte Møller Larsen; Sofie Tjagvad Jensen; Laila Brock Andersen; Pelle Thonning Olesen
Source:
Food control 2023 v.143 pp. 109322
ISSN:
0956-7135
Subject:
medicinal properties,   etc   ; food safety; glycyrrhizin; ice cream; ingestion; licorice; markets; risk; sweets; tea; Denmark;     Show all 11 Subjects
Abstract:
... Glycyrrhizinic acid (GA) is a natural compound found in licorice root and its extract, and is used in a large number of food products. It has been documented that excess consumption of licorice can cause adverse health effects, due to their content of GA. Mandatory labelling rules are therefore in place in the EU to inform consumers of the possible adverse health effects. In this study, 219 sample ...
DOI:
10.1016/j.foodcont.2022.109322

2. Et3N catalyzed direct α-addition cascade isomerization of deconjugated butenolides with α-ketoesters for the synthesis of α,γ-disubstituted butenolide derivatives

Author:
Zhe-Yao Huang; Hong Yang; Lin Zhou; Qing-Han Li; Zhi-Gang Zhao
Source:
Tetrahedron 2022 v.112 pp. 132740
ISSN:
0040-4020
Subject:
medicinal properties,   etc   ; catalysts; isomerization;     Show all 3 Subjects
Abstract:
... The α,γ-disubstituted butenolides are widespread occurrences in numerous pharmacologically active molecules. In this paper, a highly efficient method for the synthesis of α,γ-disubstituted butenolide derivatives via a direct α-addition cascade isomerization of deconjugated butenolides with α-ketoesters using Et₃N as catalyst, has been successfully developed. A series of α,γ-disubstituted butenolid ...
DOI:
10.1016/j.tet.2022.132740

3. Recent advances in the synthesis of pyrazole scaffolds via nanoparticles: A review

Author:
Hedieh Rostami; Lotfi Shiri; Zahra Khani
Source:
Tetrahedron 2022 v.110 pp. 132688
ISSN:
0040-4020
Subject:
medicinal properties,   etc   ; heterocyclic compounds; nanoparticles;     Show all 3 Subjects
Abstract:
... One important class of heterocyclic compounds, are pyrazole derivatives. These compounds consist of a pyrazole core and have many biological and pharmacological activities. Also, some of natural products having pyrazole molecules in their structures that give particular properties to these compounds. Today, interesting to nanoparticles due to the special characteristics of them for the organic syn ...
DOI:
10.1016/j.tet.2022.132688

4. Regioselective synthesis of the 4,5-dialkoxy-2-nitroanilines bearing two different alkoxy substituents

Author:
Jarosław Grolik; Paweł Ręka; Magdalena Gorczyca; Katarzyna Stadnicka
Source:
Tetrahedron letters 2022 v.99 pp. 153830
ISSN:
0040-4039
Subject:
medicinal properties,   etc   ; antimalarials; chemoselectivity; regioselectivity;     Show all 4 Subjects
Abstract:
... This article reports the regioselective and chemoselective synthesis of 4,5-dialkoxy-2-nitroanilines substituted with two alkoxys at C-4 and C-5. Here we show the optimization protocol of the transetherification reaction used to synthesize 20 new compounds with good to excellent yields (50–92%). We describe a simple and efficient one-step procedure that can be applied to obtain a significant numbe ...
DOI:
10.1016/j.tetlet.2022.153830

5. Structural derivatization strategies of natural phenols by semi-synthesis and total-synthesis

Author:
Ding Lin; Senze Jiang; Ailian Zhang; Tong Wu; Yongchang Qian; Qingsong Shao
Source:
Natural products and bioprospecting 2022 v.12 no.1 pp. 8
ISSN:
2192-2195
Subject:
medicinal properties,   etc   ; chalcones; derivatization; phenol; skeleton; stilbenes;     Show all 6 Subjects
Abstract:
... Structural derivatization of natural products has been a continuing and irreplaceable source of novel drug leads. Natural phenols are a broad category of natural products with wide pharmacological activity and have offered plenty of clinical drugs. However, the structural complexity and wide variety of natural phenols leads to the difficulty of structural derivatization. Skeleton analysis indicate ...
DOI:
10.1007/s13659-022-00331-6

6. Recent advances in medicinal and edible homologous polysaccharides: Extraction, purification, structure, modification, and biological activities

Author:
Hongkun Xue; Wenli Wang; Jiayue Bian; Yuchao Gao; Zitong Hao; Jiaqi Tan
Source:
International journal of biological macromolecules 2022 v.222 pp. 1110-1126
ISSN:
0141-8130
Subject:
medicinal properties,   etc   ; antioxidants; intestinal microorganisms; medicine; polysaccharides; therapeutics;     Show all 6 Subjects
Abstract:
... 110 kinds of traditional Chinese medicines can be used for medicine and food from Chinese pharmacopoeia in 2021. With the deepening of research in recent years, medicinal and edible homologous (MEH) traditional Chinese medicines have great development and application prospects in many fields. Polysaccharides are one of the major and representative pharmacologically active macromolecules in traditi ...
DOI:
10.1016/j.ijbiomac.2022.09.227

7. Donor–Acceptor Stenhouse Adduct Displaying Reversible Photoswitching in Water and Neuronal Activity

Author:
Rossella Castagna; Galyna Maleeva; Deborah Pirovano; Carlo Matera; Pau Gorostiza
Source:
Journal of the American Chemical Society 2022 v.144 no.34 pp. 15595-15602
ISSN:
1520-5126
Subject:
medicinal properties,   etc   ; brain; cyclodextrins; ingredients; medicine; neurons; pH; phenobarbital; solubility;     Show all 9 Subjects
Abstract:
... The interest in the photochromism and functional applications of donor–acceptor Stenhouse adducts (DASAs) soared in recent years owing to their outstanding advantages and flexible design. However, their low solubility and irreversible conversion in aqueous solutions hampered exploring DASAs for biology and medicine. It is notably unknown whether the barbiturate electron acceptor group retains the ...
DOI:
10.1021/jacs.2c04920

8. Research Progress on the Extraction, Structure, and Bioactivities of Polysaccharides from Coriolus versicolor

Author:
Yongshuai Jing; Shilin Zhang; Mingsong Li; Yunfeng Ma; Yuguang Zheng; Danshen Zhang; Lanfang Wu
Source:
Foods 2022 v.11 no.14 pp. -
ISSN:
2304-8158
Subject:
medicinal properties,   etc   ; Coriolus versicolor; active ingredients; fungi; immune response; polysaccharides;     Show all 6 Subjects
Abstract:
... Coriolus is the dried fruiting body of Coriolus versicolor (L. ex Fr.) Quel. C. versicolor (CV) is a worldwide-distributed fungus, which is common and widely used in primitive forests in the northern hemisphere. Polysaccharide, as the main active ingredient in CV, has a variety of biological activities, such as promoting immune function, antivirus, antitumor, anti-diabetes, and so on. However, Cor ...
DOI:
10.3390/foods11142126

9. Strategies for sustained release of heparin: A review

Author:
Xuewen Yang; Qiuxiang Wang; Aiwen Zhang; Xinyao Shao; Tianqing Liu; Bo Tang; Guihua Fang
Source:
Carbohydrate polymers 2022 v.294 pp. 119793
ISSN:
0144-8617
Subject:
medicinal properties,   etc   ; durability; half life; heparin; patient compliance; therapeutics; thrombosis;     Show all 7 Subjects
Abstract:
... Heparin, a sulfate-containing linear polysaccharide, has proven preclinical and clinical efficacy for a variety of disorders. Heparin, including unfractionated heparin (UFH), low-molecular-weight heparin (LMWH), and ultra-low-molecular-weight heparin (ULMWH), is administered systematically, in the form of a solution in the clinic. However, it is eliminated quickly, due to its short half-life, espe ...
DOI:
10.1016/j.carbpol.2022.119793

10. Two new flavonol derivatives from the whole plants of Centella asiatica and their cytotoxic activities

Author:
Jingzhe Zheng; Qi Zhou; Xiaocheng Cao; Yongjun Meng; Guowei Jiang; Ping Xu
Source:
Phytochemistry letters 2022 v.47 pp. 34-37
ISSN:
1874-3900
Subject:
medicinal properties,   etc   ; Centella asiatica; cytotoxicity; flavonols; humans; medicinal plants; spectroscopy;     Show all 7 Subjects
Abstract:
... Centella asiatica is well known as an important medicinal plant because of its various pharmacological effects. However, most investigations on C. asiatica focused on the pharmacological activity of its extract or asiatic acid. In the present work, we aimed to explore the bioactive compounds of the whole plants of C. asiatica. As a result, seven compounds including two new flavonol derivates named ...
DOI:
10.1016/j.phytol.2021.10.012

11. Catalytic function, mechanism, and application of plant acyltransferases

Author:
Linlin Wang; Kuan Chen; Meng Zhang; Min Ye; Xue Qiao
Source:
Critical reviews in biotechnology 2022 v.42 no.1 pp. 125-144
ISSN:
1549-7801
Subject:
medicinal properties,   etc   ; acyltransferases; biotechnology; catalytic activity; heterologous gene expression; lipids; solubility;     Show all 7 Subjects
Abstract:
... Acyltransferases (ATs) are important tailoring enzymes that contribute to the diversity of natural products. They catalyze the transfer of acyl groups to the skeleton, which improves the lipid solubility, stability, and pharmacological activity of natural compounds. In recent years, a number of ATs have been isolated from plants. In this review, we have summarized 141 biochemically characterized A ...
DOI:
10.1080/07388551.2021.1931015

12. Diterpenes of Scutellaria spp.: Phytochemistry and pharmacology

Author:
Sina Maleki; Toktam Akaberi; Seyed Ahmad Emami; Maryam Akaberi
Source:
Phytochemistry 2022 v.201 pp. 113285
ISSN:
0031-9422
Subject:
medicinal properties,   etc   ; Scutellaria; antifeedants; diterpenoids; flavonoids; metabolites; nitric oxide; phytotoxicity; therapeutics;     Show all 9 Subjects
Abstract:
... Scutellaria genus, a member of the Lamiaceae family, distributed worldwide and known as skullcaps, contains a wide range of pharmacologically active constituents including flavonoids and diterpenes. There are different classes of diterpenes in the plant kingdom, of which many have medicinal applications. Scutellaria spp. contain neo-clerodane diterpenes, a large group of naturally occurring specia ...
DOI:
10.1016/j.phytochem.2022.113285

13. The potential health benefits of aloin from genus Aloe

Author:
Jianbin Xiao; Siyuan Chen; Youqiang Chen; Jingqian Su
Source:
Phytotherapy research 2022 v.36 no.2 pp. 873-890
ISSN:
0951-418X
Subject:
medicinal properties,   etc   ; Aloe; active ingredients; antioxidants; mechanism of action; phytotherapy; research; toxicology;     Show all 8 Subjects
Abstract:
... The Aloe species is known for its medicinal and cosmetic properties. Aloin is an active ingredient found in the leaves of medicinal plants of the genus Aloe. Aloin has attracted considerable interest for its antiinflammatory, anticancer, antibacterial, and antioxidant activities. However, since its clinical application is restricted by its unclear mechanism of action, a deeper understanding of its ...
DOI:
10.1002/ptr.7371

14. Brain-derived neurotrophic factor for high-throughput evaluation of selective Sigma-1 receptor ligands

Author:
Dhwanil A. Dalwadi; Stephanie Kim; John Schetz; Derek A. Schreihofer; Seongcheol Kim
Source:
Journal of pharmacological and toxicological methods 2022 v.113 pp. 107129
ISSN:
1056-8719
Subject:
medicinal properties,   etc   ; agonists; antagonists; brain; calcium; drugs; endoplasmic reticulum; ligands; neurites; therapeutics; toxicology;     Show all 11 Subjects
Abstract:
... The Sigma-1 receptor (S1R) is an endoplasmic reticulum (ER) chaperone protein that has been implicated in attenuating inflammatory stress-mediated brain injuries. Selective S1R agonists represent a new class of therapeutic agent for treating neuropsychiatric and neurodegenerative disorders, however, to date, no S1R ligand has been approved for therapeutic purposes. We used three potential methods ...
DOI:
10.1016/j.vascn.2021.107129

15. The Anti-Candida Activity of Tephrosia apollinea Is More Superiorly Attributed to a Novel Steroidal Compound with Selective Targeting

Author:
Naglaa S. Ashmawy; Eman M. El-labbad; Alshaimaa M. Hamoda; Ali A. El-Keblawy; Abdel-Nasser A. El-Shorbagi; Kareem A. Mosa; Sameh S. M. Soliman
Source:
Plants 2022 v.11 no.16 pp. -
ISSN:
2223-7747
Subject:
medicinal properties,   etc   ; Candida; Tephrosia; chromatography; computer simulation; enzyme substrates; flavonoids; methanol; multiple drug resistance;     Show all 9 Subjects
Abstract:
... Tephrosia is widely distributed throughout tropical, subtropical, and arid regions. This genus is known for several biological activities, including its anti-Candida activity, which is mainly attributed to prenylated flavonoids. The biological activities of most Tephrosia species have been studied, except T. apollinea. This study was conducted to investigate the underlying anti-Candida activity of ...
DOI:
10.3390/plants11162120

16. Evolution of Pharmacological activity with Molecular Docking of active constituents present in roots and small branches of Aegle Marmelos: A comparative study using HPLC, GC–MS, LC-MS

Author:
Ajay Kumar Meena; R. Ilavarasan; Ravindra Singh; Deepesh Parashar; Mohit Motiwale; Ayyam Perumal; N. Srikanth; K.S. Dhiman
Source:
Phytomedicine plus 2022 v.2 no.1 pp. 100210
ISSN:
2667-0313
Subject:
medicinal properties,   etc   ; Aegle marmelos; comparative study; ethanol; evolution; leaves; oxidoreductases; phytochemicals; quantitative analysis; India;     Show all 10 Subjects
Abstract:
... Aegle marmelos is a traditional plant belonging to India. Very few and sporadic works are there in the literature regarding the physicochemical evaluation of the plant. The major parameters of this study includes the quantification marmelosine, WHO-recommended physicochemical investigation, preliminary phytochemical examination and chemical profiling using advanced techniques like HPLC, LC-MS, and ...
DOI:
10.1016/j.phyplu.2021.100210

17. An updated review of extraction and liquid chromatography techniques for analysis of phenolic compounds in honey

Author:
Norfarizah Hanim Hassan; Francesco Cacciola; Ngee Sing Chong; Katia Arena; Philip J. Marriott; Yong Foo Wong
Source:
Journal of food composition and analysis 2022 v.114 pp. 104751
ISSN:
0889-1575
Subject:
medicinal properties,   etc   ; flavonoids; food composition; honey; liquid chromatography; mass spectrometry; polyphenols; qualitative analysis; surveys;     Show all 9 Subjects
Abstract:
... Over the past decade, the measurement of phenolics and flavonoids in honey has received much attention, which is attributed to their broad spectrum of beneficial pharmacological activity and their potential to address issues related to the authenticity and botanical origin of honey. Due to their high variability in structural and physicochemical properties, the separation, detection and identifica ...
DOI:
10.1016/j.jfca.2022.104751

18. Antidiabetic compounds from medicinal plants traditionally used for the treatment of diabetes in Africa: A review update (2015–2020)

Author:
Aminu Mohammed; Nasir Tajuddeen
Source:
South African journal of botany 2022 v.146 pp. 585-602
ISSN:
0254-6299
Subject:
medicinal properties,   etc   ; apigenin; biodiversity; diabetes mellitus; glycemic effect; kaempferol; metabolites; quercetin; traditional medicine; triterpenoids; Africa;     Show all 11 Subjects
Abstract:
... Africa has a rich biodiversity of plants and an active traditional medicine system that takes advantage of the rich biodiversity to treat various diseases, including diabetes mellitus (DM). The folkloric use of some of these plants in treating diabetes has been documented in various databases and publications, and validated with in vitro and in vivo models. In this regard ethnopharmacology remains ...
DOI:
10.1016/j.sajb.2021.11.018

19. Steroidal saponin from Agave marmorata Roezl modulates inflammatory response by inhibiting NF-κB and AP-1

Author:
Jonathan Cortés A; Ernesto Sánchez-Mendoza; Alejandro Zamilpa; Manases González-Cortazar; Maribel Herrera-Ruiz; Julio Cesar Almanza-Pérez; Eli Terán-Cabanillas; Renaud Condé; Lenin Domínguez-Ramírez; Elizur Montiel Arcos; Jesús Enrique Jiménez-Ferrer
Source:
Natural product research 2022 v.36 no.4 pp. 1123-1128
ISSN:
1478-6427
Subject:
medicinal properties,   etc   ; Agave; bioinformatics; chemistry; immunomodulation; inflammation; macrophages; phosphatidylinositol 3-kinase; research; steroid saponins; Mexico;     Show all 11 Subjects
Abstract:
... Agave marmorata Roezl is an endemic succulent specie from the Oaxaca-Puebla area of Mexico. This plant is a medicinal recourse and contain a rich variety of saponins-type compounds with multiples biological effects. Some of them have been shown to be anticancer, antibacterial, or having anti-inflammatory and immunoregulation effects. This paper is the first scientific report to describe the pharma ...
DOI:
10.1080/14786419.2020.1855638

20. Validation of the traditional medicinal use of a Mexican endemic orchid (Prosthechea karwinskii) through UPLC-ESI-qTOF-MS/MS characterization of its bioactive compounds

Author:
Gabriela Soledad Barragán-Zarate; Luicita Lagunez-Rivera; Rodolfo Solano; Candy Carranza-Álvarez; Diego Manuel Hernández-Benavides; Gerard Vilarem
Source:
Heliyon 2022 v.8 no.7 pp. e09867
ISSN:
2405-8440
Subject:
medicinal properties,   etc   ; Orchidaceae; abortion (animals); antioxidant activity; cough; diabetes; flavonoids; labor; phenol; principal component analysis; Mexico;     Show all 11 Subjects
Abstract:
... The orchid Prosthechea karwinskii is a medicinal orchid in Oaxaca, Mexico, used to treat diabetes, cough, wounds, and burns, prevent miscarriage and assist in labor. Each part of the plant (leaves, pseudobulbs, or flowers) is used by healers for certain treatment conditions, indicating that each part has different biocompounds with specific pharmacological activity. To characterize the biocompound ...
DOI:
10.1016/j.heliyon.2022.e09867