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1. Evaluation of factors reported by veterinarians who chose not to enter clinical academic veterinary medicine

Author:
Furr, Martin O.
Source:
Journal of the American Veterinary Medical Association 2020 v.256 no.6 pp. 701-707
ISSN:
0003-1488
Subject:
medicine; veterinary medicine,   etc   ; females; males; surveys; veterinarians;     Show all 6 Subjects
Abstract:
... OBJECTIVE To identify factors that may have influenced veterinarians’ decisions to not pursue careers in clinical academic veterinary medicine. SAMPLE 363 board-certified veterinarians. PROCEDURES An online survey, open from July 7 to July 21, 2015, was used to gather data from board-certified veterinarians who were members of ≥ 1 of the 22 specialty organizations recognized by the American Board ...
DOI:
10.2460/javma.256.6.701

2. Herbal medicine treatments for essential tremor: A retrospective chart review study

Author:
Kang, Ahreum; Moon, Sang-Kwan; Cho, Seung-Yeon; Park, Seong-Uk; Jung, Woo-Sang; Park, Jung-Mi; Ko, Chang-Nam; Cho, Ki-Ho; Kwon, Seungwon
Source:
Journal of herbal medicine 2020 v.19 pp. 100295
ISSN:
2210-8033
Subject:
herbal medicines; medicine,   etc   ; females; hospitals; patients;     Show all 5 Subjects
Abstract:
... The purpose of this study was to assess the effectiveness of Korean herbal medicine treatment for patients with essential tremor (ET).This study was a retrospective chart review of patients who visited the Kyung Hee University Korean Medicine Hospital and received herbal medicine treatment for ET between January 2010 and August 2015. Treatment outcomes were evaluated based on the change in Numeric ...
DOI:
10.1016/j.hermed.2019.100295

3. Emerging Modalities and Implantable Technologies for Neuromodulation

Author:
Won, Sang Min; Song, Enming; Reeder, Jonathan T.; Rogers, John A.
Source:
Cell 2020 v.181 no.1 pp. 115-135
ISSN:
0092-8674
Subject:
medicine,   etc   ; patients; prostheses;     Show all 3 Subjects
Abstract:
... Techniques for neuromodulation serve as effective routes to care of patients with many types of challenging conditions. Continued progress in this field of medicine will require (1) improvements in our understanding of the mechanisms of neural control over organ function and (2) advances in technologies for precisely modulating these functions in a programmable manner. This review presents recent ...
DOI:
10.1016/j.cell.2020.02.054

4. Saliva sampling: Methods and devices. An overview

Author:
Bellagambi, Francesca G.; Lomonaco, Tommaso; Salvo, Pietro; Vivaldi, Federico; Hangouët, Marie; Ghimenti, Silvia; Biagini, Denise; Di Francesco, Fabio; Fuoco, Roger; Errachid, Abdelhamid
Source:
Trends in analytical chemistry 2020 v.124 pp. 115781
ISSN:
0165-9936
Subject:
medicine,   etc   ; biomarkers; blood; saliva;     Show all 4 Subjects
Abstract:
... The continuous exchange of chemicals with blood and the non-invasive collection make saliva an interesting specimen for clinical applications, from the detection of biomarkers to the new –omic sciences in medicine. However, saliva sampling is challenging because the suitability of the collection method for the analyte of interest is either poorly investigated or, more often, not mentioned at all i ...
DOI:
10.1016/j.trac.2019.115781

5. How German general practitioners justify their provision of complementary and alternative medicine – a qualitative study

Author:
Ostermaier, Agnes; Barth, Niklas; Linde, Klaus
Source:
BMC complementary medicine and therapies 2020 v.20 no.1 pp. 111
ISSN:
2662-7671
Subject:
alternative medicine; medicine,   etc   ; general practitioners; health insurance; interviews; patients;     Show all 6 Subjects
Abstract:
... BACKGROUND: Many German general practitioners (GPs) use complementary and alternative medicine (CAM) in their daily work although most CAM procedures are controversial from an academic point of view. OBJECTIVE: We aimed to investigate how GPs justify their use of CAM. METHODS: We performed semi-structured, individual face-to-face interviews with 20 purposively sampled, experienced GPs providing pr ...
DOI:
10.1186/s12906-020-02907-6
PubMed:
32293399
PubMed Central:
PMC7158128

6. Colorimetric detection of miRNA-21 by DNAzyme-coupled branched DNA constructs

Author:
Hosseinzadeh, Elyas; Ravan, Hadi; Mohammadi, Abbas; Pourghadamyari, Hossein
Source:
Talanta 2020 v.216 pp. 120913
ISSN:
0039-9140
Subject:
medicine; precision medicine,   etc   ; DNA; hybridization chain reaction; microRNA; oxidation;     Show all 6 Subjects
Abstract:
... Fluctuation of nucleic acid expression and ultrasensitive and specific detection of these variations in expression is a crucial subject in molecular medicine and clinical theranostics. A novel DNAzyme-coupled branched hybridization chain reaction (b-HCR) assay is reported for efficient signal-amplified detection of miRNA in this study. This assay was composed of a translator (T) hybridized with mi ...
DOI:
10.1016/j.talanta.2020.120913

7. The Master Observational Trial: A New Class of Master Protocol to Advance Precision Medicine

Author:
Dickson, Dane; Johnson, Jennifer; Bergan, Raymond; Owens, Rebecca; Subbiah, Vivek; Kurzrock, Razelle
Source:
Cell 2020 v.180 no.1 pp. 9-14
ISSN:
0092-8674
Subject:
medicine; precision medicine,   etc   ; clinical trials; data collection; ecosystems;     Show all 5 Subjects
Abstract:
... This commentary introduces a new clinical trial construct, the Master Observational Trial (MOT), which hybridizes the power of molecularly based master interventional protocols with the breadth of real-world data. The MOT provides a clinical venue to allow molecular medicine to rapidly advance, answers questions that traditional interventional trials generally do not address, and seamlessly integr ...
DOI:
10.1016/j.cell.2019.12.009

8. The Third International Symposium on Fungal Stress – ISFUS

Author:
Alder-Rangel, Alene; Idnurm, Alexander; Brand, Alexandra C.; Brown, Alistair J.P.; Gorbushina, Anna; Kelliher, Christina M.; Campos, Claudia B.; Levin, David E.; Bell-Pedersen, Deborah; Dadachova, Ekaterina; Bauer, Florian F.; Gadd, Geoffrey M.; Braus, Gerhard H.; Braga, Gilberto U.L.; Brancini, Guilherme T.P.; Walker, Graeme M.; Druzhinina, Irina; Pócsi, István; Dijksterhuis, Jan; Aguirre, Jesús; Hallsworth, John E.; Schumacher, Julia; Wong, Koon Ho; Selbmann, Laura; Corrochano, Luis M.; Kupiec, Martin; Momany, Michelle; Molin, Mikael; Requena, Natalia; Yarden, Oded; Cordero, Radamés J.B.; Fischer, Reinhard; Pascon, Renata C.; Mancinelli, Rocco L.; Emri, Tamas; Basso, Thiago O.; Rangel, Drauzio E.N.
Source:
Fungal biology 2020 v.124 no.5 pp. 235-252
ISSN:
1878-6146
Subject:
medicine,   etc   ; biotechnology; ecology; fungi; Brazil;     Show all 5 Subjects
Abstract:
... Stress is a normal part of life for fungi, which can survive in environments considered inhospitable or hostile for other organisms. Due to the ability of fungi to respond to, survive in, and transform the environment, even under severe stresses, many researchers are exploring the mechanisms that enable fungi to adapt to stress. The International Symposium on Fungal Stress (ISFUS) brings together ...
DOI:
10.1016/j.funbio.2020.02.007

9. « Être », « se croire » ou « se sentir » allergique. Les enjeux du recours aux tests anti-aliments dans la mise en place individuelle de l’éviction du lait de vache et des aliments contenant du gluten

Author:
Lefranc, Emmanuelle
Source:
Cahiers de nutrition et de diététique 2020 v.55 no.2 pp. 89-98
ISSN:
0007-9960
Subject:
medicine,   etc   ; allergenicity; food allergies; gluten;     Show all 4 Subjects
Abstract:
... Food evictions are frequent and would often be justified by allergy. But “to be considered allergic”, you must be diagnosed as such. However, the prevalence of food allergies is low, and it is possible to think that people feel allergic to themselves. Our study shows that the reference to allergy is a strategy used to facilitate the acceptance of eviction but also that respondents declaring themse ...
DOI:
10.1016/j.cnd.2020.01.004

10. A review of the antimicrobial potential of herbal drugs used in popular Italian medicine (1850s–1950s) to treat bacterial skin diseases

Author:
Mazzei, Rosalucia; Leonti, Marco; Spadafora, Santo; Patitucci, Alessandra; Tagarelli, Giuseppe
Source:
Journal of ethnopharmacology 2020 v.250 pp. 112443
ISSN:
0378-8741
Subject:
alternative medicine; herbal medicines; traditional medicine,   etc   ; antibacterial properties; antibiotics; in vitro studies; in vivo studies; ingredients; Italy;     Show all 9 Subjects
Abstract:
... Before the advent of modern antibiotics, microbial infections were treated with herbal medicine or cauterization. Literature from the latter half of the nineteenth to the early mid-twentieth century, when antibiotics became widely available, arguably holds the most progressive information about herbal remedies to treat bacterial skin diseases. The corpus of literature produced in Italy during that ...
DOI:
10.1016/j.jep.2019.112443

11. Implementing Culinary Medicine Training: Collaboratively Learning the Way Forward

Author:
Sicker, Kelsey; Habash, Diane; Hamilton, Lisa; Nelson, Nicolas G.; Robertson-Boyd, Laura; Shaikhkhalil, Ala K.
Source:
Journal of nutrition education and behavior 2020 v.52 no.7 pp. 742-746
ISSN:
1499-4046
Subject:
medicine,   etc   ; diet counseling; learning; nutrition education;     Show all 4 Subjects
Abstract:
... There is a documented substantial gap between the level of nutrition education for medical trainees and the need to provide nutrition counseling. Culinary medicine offers a solution, but there are multiple barriers and no guides to implementation. This article identifies core components and strategies to overcome barriers on the basis of experiences of multiple institutions. The outline forms a fo ...
DOI:
10.1016/j.jneb.2019.12.009

12. Extracellular blebs: Artificially-induced extracellular vesicles for facile production and clinical translation

Author:
Thone, Melissa N.; Kwon, Young Jik
Source:
Methods 2020 v.177 pp. 135-145
ISSN:
1046-2023
Subject:
precision medicine,   etc   ; extrusion; proteins; shear stress;     Show all 4 Subjects
Abstract:
... Extracellular vesicles (EVs) have emerged as promising biologic and comprehensive therapies for precision medicine. Despite their potential demonstrated at the benchtop, few EV formulations have made it to the clinic due to challenges in regulatory compliant scalable production; including purity, homogeneity, and reproducibility. For translation of this technology, there is a strong need for novel ...
DOI:
10.1016/j.ymeth.2019.11.007

13. Arsenic and arsenic speciation in mushrooms from China: A review

Author:
Zhang, Ji; Barałkiewicz, Danuta; Wang, Yuanzhong; Falandysz, Jerzy; Cai, Chuantao
Source:
Chemosphere 2020 v.246 pp. 125685
ISSN:
0045-6535
Subject:
medicine,   etc   ; arsenic; humans; mushrooms; risk; soil; China;     Show all 7 Subjects
Abstract:
... Arsenic (As) is a natural environmental contaminant to which humans are usually exposed in water, air, soil, and food. China is a typical high-As region, and also a great contributor of the world production of cultivated edible mushrooms and a region abundant in wild growing edible mushrooms. Mushrooms can accumulate different amounts of As and different As compounds, so potential health risk of A ...
DOI:
10.1016/j.chemosphere.2019.125685

14. How Machine Learning Will Transform Biomedicine

Author:
Goecks, Jeremy; Jalili, Vahid; Heiser, Laura M.; Gray, Joe W.
Source:
Cell 2020 v.181 no.1 pp. 92-101
ISSN:
0092-8674
Subject:
medicine,   etc   ; artificial intelligence; diagnostic techniques; monitoring;     Show all 4 Subjects
Abstract:
... This Perspective explores the application of machine learning toward improved diagnosis and treatment. We outline a vision for how machine learning can transform three broad areas of biomedicine: clinical diagnostics, precision treatments, and health monitoring, where the goal is to maintain health through a range of diseases and the normal aging process. For each area, early instances of successf ...
DOI:
10.1016/j.cell.2020.03.022
PubMed:
32243801
PubMed Central:
PMC7141410

15. Snapshot: Trial Types in Precision Medicine

Author:
Dickson, Dane; Johnson, Jennifer; Bergan, Raymond; Owens, Rebecca; Subbiah, Vivek; Kurzrock, Razelle
Source:
Cell 2020 v.181 no.1 pp. 208
ISSN:
0092-8674
Subject:
precision medicine,   etc   ; biomarkers; data collection; diagnostic techniques;     Show all 4 Subjects
Abstract:
... Integrating precision diagnostics into personalized treatments requires understanding how biomarkers relate to clinical outcomes. Various clinical data collection methods exist, each with strengths and weaknesses. Interventional data are high quality but narrowly focused. Real-world data (RWD) provide broader information but with variable quality. Master protocols allow better efficiency in data c ...
DOI:
10.1016/j.cell.2020.02.032

16. Photoactivatable fluorescent probes for spatiotemporal-controlled biosensing and imaging

Author:
Zou, Zhen; Luo, Ziling; Xu, Xuan; Yang, Sheng; Qing, Zhihe; Liu, Juewen; Yang, Ronghua
Source:
Trends in analytical chemistry 2020 v.125 pp. 115811
ISSN:
0165-9936
Subject:
medicine,   etc   ; enzyme activity; fluorescent dyes; image analysis;     Show all 4 Subjects
Abstract:
... Designing fluorescent probes for accurately analyzing target molecules of interest become fascinating and vital in the view of biology and biomedicine. Conventional fluorescent probes are often obscured by the interference from biological autofluorescence, off-target effects, and a lack of spatiotemporal control. As a newly developed paradigm, photoactivatable fluorescent probes (PFPs), whose sens ...
DOI:
10.1016/j.trac.2020.115811

17. Leveling Up Hydrogels: Hybrid Systems in Tissue Engineering

Author:
Neves, Sara C.; Moroni, Lorenzo; Barrias, Cristina C.; Granja, Pedro L.
Source:
Trends in biotechnology 2020 v.38 no.3 pp. 292-315
ISSN:
0167-7799
Subject:
medicine,   etc   ; hydrogels; manmade structures; tissue engineering;     Show all 4 Subjects
Abstract:
... Hydrogels can mimic several features of the cell native microenvironment and have been widely used as synthetic extracellular matrices (ECMs) in tissue engineering and regenerative medicine (TERM). However, some applications have specifications that hydrogels cannot efficiently fulfill on their own. Incorporating reinforcing structures like fibrous scaffolds or particles into hydrogels, as hybrid ...
DOI:
10.1016/j.tibtech.2019.09.004

18. Looking back on 45 years of canine dermatology

Author:
Scott, Danny W.
Source:
The veterinary journal 2020 v.257 pp. 105438
ISSN:
1090-0233
Subject:
veterinary medicine,   etc   ; cats; dogs; horses; kennels;     Show all 5 Subjects
Abstract:
... In June 2018, I was honored (and flabbergasted!) to receive the Kennel Club Charitable Trust’s Lifetime Achievement Award for research in the field of canine health, sponsored by Vernon and Shirley Hill of Metro Bank, and administered by the Kennel Club Charitable Trust. I entered the arena of veterinary dermatology in 1971, a graduate of the University of California, Davis. I retired from Cornell ...
DOI:
10.1016/j.tvjl.2020.105438

19. Neodymium-containing contrast induces mummification of neutrophil granulocytes

Author:
Pleskova, Svetlana; Kryukov, Ruslan; Boryakov, Alexey; Gorshkova, Ekaterina
Source:
Environmental pollution 2020 v.258 pp. 113664
ISSN:
0269-7491
Subject:
medicine,   etc   ; calcium; cell death; lanthanides; neutrophils;     Show all 5 Subjects
Abstract:
... Recently, chemical compounds containing lanthanides were used in various fields of biology and medicine. It has been described that such compounds can be applied in scanning electron microscopy (SEM) to increase the contrast and simplify the sample preparation process due to the process of replacing calcium with lanthanides in cell. However cell death by different mechanisms under influence of lan ...
DOI:
10.1016/j.envpol.2019.113664

20. Subjective and objective evaluations of horses for fit-to-compete or unfit-to-compete judgement

Author:
Serra Bragança, F.M.; Bragança, F.M. Serra; Brommer, H.; van den Belt, A.J.M.; Maree, J.T.M.; van Weeren, P.R.; van Oldruitenborgh-Oosterbaan, M.M. Sloet
Source:
The veterinary journal 2020 v.257 pp. 105454
ISSN:
1090-0233
Subject:
veterinary medicine,   etc   ; decision making; gait; horses;     Show all 4 Subjects
Abstract:
... At Fédération Equestre Internationale (FEI) competitions, horses undergo veterinary inspection for judgement of ‘fit-to-compete’. However, FEI Veterinary Delegates (VDs) often differ in opinion. The aim of the present study was to evaluate intra- and inter-observer agreements of fit-to-compete judgement and compare these with objective gait analysis measurements. Twelve horses were evaluated by th ...
DOI:
10.1016/j.tvjl.2020.105454