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1. Comparative efficacy of Chinese herbal injections for treating chronic heart failure: a network meta-analysis

Author:
Wang, Kai-Huan; Wu, Jia-Rui; Zhang, Dan; Duan, Xiao-Jiao; Ni, Meng-Wei
Source:
BMC complementary and alternative medicine 2018 v.18 no.1 pp. 1-41
ISSN:
1472-6882
Subject:
alternative medicine; medicine,   etc   ; cardiac output; computer software; heart failure; meta-analysis; risk;     Show all 7 Subjects
Abstract:
... BACKGROUND: On account of deterioration of chronic heart failure (CHF) and extensive exploration of Chinese herbal injections (CHIs), we performed a network meta-analysis to investigate the efficacy of CHIs (Huangqi injection, Shenfu injection, Shengmai injection, Shenmai injection, Shenqi Fuzheng injection, Yiqifumai injection) on the basis of western medicine (WM) treatment in CHF. METHODS: Lite ...
DOI:
10.1186/s12906-018-2090-3

2. Genotoxicity evaluation of So-ochim-tang-gamibang (SOCG), a herbal medicine

Author:
Lee, MiYoung; Park, Yang-Chun; Jin, Mirim; Kim, Eunseok; Choi, JeongJune; Jung, InChul
Source:
BMC complementary and alternative medicine 2018 v.18 no.1 pp. 1-47
ISSN:
1472-6882
Subject:
alternative medicine; herbal medicines; medicine,   etc   ; Ames test; Chinese hamsters; Escherichia coli; Salmonella Typhimurium; batteries; chromosome aberrations; genes; genotoxicity; lungs; mice; micronucleus tests; mutagens; mutation; risk; Korean Peninsula;     Show all 18 Subjects
Abstract:
... BACKGROUND: So-ochim-tang-gamibang (SOCG) is a traditional Korean medicine frequently used for depression in the clinical field. In this study, we evaluated the potential genotoxicity of SOCG using three standard batteries of tests as part of a safety evaluation. METHODS: SOCG was evaluated for potential genotoxic effects using the standard three tests recommended by the Ministry of Food and Drug ...
DOI:
10.1186/s12906-018-2111-2

3. Rational Optimization of Mechanism-Based Inhibitors through Determination of the Microscopic Rate Constants of Inactivation

Author:
Eiden, Carter G.; Maize, Kimberly M.; Finzel, Barry C.; Lipscomb, John D.; Aldrich, Courtney C.
Source:
Journal of the American Chemical Society 2017 v.139 no.21 pp. 7132-7135
ISSN:
1520-5126
Subject:
medicine,   etc   ; chemistry; kinetics;     Show all 3 Subjects
Abstract:
... Mechanism-based inhibitors (MBIs) are widely employed in chemistry, biology, and medicine because of their exquisite specificity and sustained duration of inhibition. Optimization of MBIs is complicated because of time-dependent inhibition resulting from multistep inactivation mechanisms. The global kinetic parameters kᵢₙₐcₜ and KI have been used to characterize MBIs, but they provide far less inf ...
DOI:
10.1021/jacs.7b00962

4. Cell death: From initial concepts to pathways to clinical applications – Personal reflections of a clinical researcher

Author:
Debatin, Klaus-Michael
Source:
Biochemical and biophysical research communications 2017 v.482 pp. 445-449
ISSN:
0006-291X
Subject:
medicine,   etc   ; apoptosis; homeostasis; pathophysiology;     Show all 4 Subjects
Abstract:
... Cell death research has come a long way from the description of cellular phenomena to identification of pathways to the role of apoptosis in tissue homeostasis in the pathophysiology of diseases and the delineation of targets for therapeutic intervention. In this very personal view of a clinical researcher in the field from the very beginning to recent clinical application, essential elements of c ...
DOI:
10.1016/j.bbrc.2016.10.124

5. Correction to: Inhibition of autophagy enhances synergistic effects of Salidroside and anti-tumor agents against colorectal cancer

Author:
Li, Hai; Chen, Chen
Source:
BMC complementary and alternative medicine 2018 v.18 no.1 pp. 1-72
ISSN:
1472-6882
Subject:
alternative medicine,   etc   ; antineoplastic agents; autophagy; colorectal neoplasms; funding; synergism;     Show all 6 Subjects
Abstract:
... CORRECTION: The authors of this article [1] would like the funding and acknowledgements to be disregarded. ...
DOI:
10.1186/s12906-018-2120-1

6. Is fasting safe? A chart review of adverse events during medically supervised, water-only fasting

Author:
Finnell, JohnS.; Saul, BradleyC.; Goldhamer, AlanC.; Myers, ToshiaR.
Source:
BMC complementary and alternative medicine 2018 v.18 no.1 pp. 1-67
ISSN:
1472-6882
Subject:
alternative medicine,   etc   ; fasting; health promotion; patients; refeeding; risk; terminology;     Show all 7 Subjects
Abstract:
... BACKGROUND: Evidence suggests that fasting, during which only water is consumed, results in potentially health promoting physiological effects. However, peer-reviewed research assessing the safety of water-only fasting is lacking. To address this, we conducted a chart review to describe adverse events (AEs) that occurred during medically supervised, water-only fasting. METHODS: Electronic charts f ...
DOI:
10.1186/s12906-018-2136-6

7. Effect of contact time on variance of ground reaction forces during force platform gait analysis of a heterogeneous sample of clinically normal dogs

Author:
Hoffman, Christopher L.; Volstad, Nicola J.; Hans, Eric C.; Nemke, Brett W.; Muir, Peter
Source:
American journal of veterinary research 2018 v.79 no.5 pp. 546-554
ISSN:
0002-9645
Subject:
veterinary medicine,   etc   ; dogs; gait; lameness; shoulders; variance; withers;     Show all 7 Subjects
Abstract:
... OBJECTIVE To develop contact time (ConT) and withers height-normalized relative ConT (ConT*) for force platform gait analysis of dogs. ANIMALS 29 healthy client-owned dogs. PROCEDURES Height at the most dorsal aspect of the shoulders (withers) was measured with a framing square. Dogs were trotted across a force platform at their preferred velocity with controlled acceleration (± 0.5 m/s2). Ranges ...
DOI:
10.2460/ajvr.79.5.546

8. Effect of oral administration of robenacoxib on inhibition of paracentesis-induced blood-aqueous barrier breakdown in healthy cats

Author:
Sharpe, Emily K.; Meekins, Jessica M.; Roush, James K.; Rankin, Amy J.; KuKanich, Butch
Source:
American journal of veterinary research 2018 v.79 no.4 pp. 443-449
ISSN:
0002-9645
Subject:
veterinary medicine,   etc   ; adults; cats; drugs; eyes; fluorescein; oral administration;     Show all 7 Subjects
Abstract:
... OBJECTIVE To determine the effect of oral administration of robenacoxib on inhibition of anterior chamber paracentesis (ACP)-induced breakdown of the blood-aqueous barrier (BAB) and assess whether robenacoxib can cross an intact BAB in healthy cats. ANIMALS 12 healthy adult domestic shorthair cats. PROCEDURES Cats received robenacoxib (6-mg tablet in a treat, PO; n = 6) or a control treatment (tre ...
DOI:
10.2460/ajvr.79.4.443

9. A qualitative study of culturally embedded factors in complementary and alternative medicine use

Author:
Zörgő, Szilvia; Purebl, György; Zana, Ágnes
Source:
BMC complementary and alternative medicine 2018 v.18 no.1 pp. 1-25
ISSN:
1472-6882
Subject:
Oriental traditional medicine; alternative medicine,   etc   ; computer software; decision making; information sources; interviews; males; models; multicultural diversity; patients; Hungary;     Show all 11 Subjects
Abstract:
... BACKGROUND: Within the intercultural milieu of medical pluralism, a nexus of worldviews espousing distinct explanatory models of illness, our research aims at exploring factors leading to complementary and alternative medicine (CAM) use with special attention to their cultural context. METHODS: The results are based on medical anthropological fieldwork (participant observation and in-depth intervi ...
DOI:
10.1186/s12906-018-2093-0

10. Efficacy of Chinese herbal medicine Zengru Gao to promote breastfeeding: a multicenter randomized controlled trial

Author:
Wang, Shuaishuai; Zhang, Chi; Li, Cuishan; Li, Daocheng; He, Ping; Su, Zhaojuan; Li, Yanling; Ding, Yiling; Lu, Aiping
Source:
BMC complementary and alternative medicine 2018 v.18 no.1 pp. 1-53
ISSN:
1472-6882
Subject:
alternative medicine; herbal medicines,   etc   ; breast feeding; breast milk; childbirth; milk production; mothers; randomized clinical trials; women; China;     Show all 10 Subjects
Abstract:
... BACKGROUND: Breastfeeding is recommended worldwide but not fully practiced. The first week after childbirth is regarded as a critical period for increasing breast milk production. The aim of the study was to investigate whether Chinese herbal medicine Zengru Gao would result in more women breastfeeding in the first week after childbirth. METHODS: A multicenter randomized controlled trial was condu ...
DOI:
10.1186/s12906-018-2121-0

11. Traditional healing practices in rural Bangladesh: a qualitative investigation

Author:
Haque, Md.Imdadul; Chowdhury, A.B. M. Alauddin; Shahjahan, Md.; Harun, Md.Golam Dostogir
Source:
BMC complementary and alternative medicine 2018 v.18 no.1 pp. 1-62
ISSN:
1472-6882
Subject:
alternative medicine; traditional medicine,   etc   ; health services; indigenous knowledge; interviews; medicinal plants; patients; physicians; rural areas; socioeconomic status; villages; Bangladesh;     Show all 12 Subjects
Abstract:
... BACKGROUND: Traditional healing practice is an important and integral part of healthcare systems in almost all countries of the world. Very few studies have addressed the holistic scenario of traditional healing practices in Bangladesh, although these serve around 80% of the ailing people. This study explored distinctive forms of traditional healing practices in rural Bangladesh. METHODS: During J ...
DOI:
10.1186/s12906-018-2129-5

12. Traditional Mediterranean and European herbal medicines

Author:
Leonti, Marco; Verpoorte, Robert
Source:
Journal of ethnopharmacology 2017 v.199 pp. 161-167
ISSN:
0378-8741
Subject:
herbal medicines; traditional medicine,   etc   ; databases; industrialization; pharmacology; traditions;     Show all 6 Subjects
Abstract:
... Written history allows tracing back Mediterranean and European medical traditions to Greek antiquity. The epidemiological shift triggered by the rise of modern medicine and industrialization is reflected in contemporary reliance and preferences for certain herbal medicines.We sketch the development and transmission of written herbal medicine through Mediterranean and European history and point out ...
DOI:
10.1016/j.jep.2017.01.052

13. Stop measles in Switzerland – The importance of travel medicine

Author:
Bühler, Silja; Lang, Phung; Bally, Bettina; Hatz, Christoph; Jaeger, Veronika K.
Source:
Vaccine 2017 v.35 pp. 3760-3763
ISSN:
0264-410X
Subject:
medicine,   etc   ; adults; travel; vaccination; Switzerland;     Show all 5 Subjects
Abstract:
... In line with the worldwide strive to combat measles, the Swiss Federal Office of Public Heath (FOPH) launched a National Strategy for measles elimination 2011–2015. In this study, we highlight the importance of travel medicine consultations to complement measles vaccination programmes based on data from the Travel Clinic of the University of Zurich.We analysed measles vaccination data from the Zur ...
DOI:
10.1016/j.vaccine.2017.05.042

14. Perspective on 3D printing of separation membranes and comparison to related unconventional fabrication techniques

Author:
Low, Ze-Xian; Chua, Yen Thien; Ray, Brian Michael; Mattia, Davide; Metcalfe, Ian Saxley; Patterson, Darrell Alec
Source:
Journal of Membrane Science 2017 v.523 pp. 596-613
ISSN:
0376-7388
Subject:
medicine,   etc   ; artificial membranes; bioprinting; manufacturing;     Show all 4 Subjects
Abstract:
... Additive manufacturing, likewise known as 3-dimensional (3D) printing and rapid prototyping, has the ability to create almost any geometrically complex shape or feature in a range of materials across different scales. It has found its applications in various areas, such as medicine (bioprinting), art, manufacturing and engineering. On the other hand, its use in separation membrane engineering is r ...
DOI:
10.1016/j.memsci.2016.10.006

15. Two-Step Design of a Single-Doped White Phosphor with High Color Rendering

Author:
Gautier, Romain; Li, Xueyan; Xia, Zhiguo; Massuyeau, Florian
Source:
Journal of the American Chemical Society 2017 v.139 no.4 pp. 1436-1439
ISSN:
1520-5126
Subject:
medicine,   etc   ; chemical composition; color; telecommunications;     Show all 4 Subjects
Abstract:
... A strategy to design step by step an inorganic single-doped white phosphor is demonstrated. The method consists in tuning different contributions of the emission by successively controlling the chemical compositions of the solid solution or nanosegregated host matrix and the oxidation states of the single dopant. We use this approach to design a white phosphor Na₄CaMgSc₄Si₁₀O₃₀:Eu with excellent c ...
DOI:
10.1021/jacs.6b12597

16. Genotoxicity study of Ethiopian medicinal plant extracts on HepG2 cells

Author:
Kahaliw, Wubayehu; Hellman, Bjorn; Engidawork, Ephrem
Source:
BMC complementary and alternative medicine 2018 v.18 no.1 pp. 1-45
ISSN:
1472-6882
Subject:
alternative medicine; herbal medicines; traditional medicine,   etc   ; DNA; DNA damage; Otostegia; Pterolobium; Vernonia amygdalina; chloroform; comet assay; genotoxicity; hematoma; human cell lines; humans; medicinal plants; methanol; mutagens; plant extracts; variance;     Show all 19 Subjects
Abstract:
... BACKGROUND: Most of herbal medicines are used without any standard safety and toxicological trials although common assumption is that these products are nontoxic. However, this assumption is incorrect and dangerous, so toxicological studies should be done for herbal drugs. Although Pterolobium stellatum, Otostegia integrifolia and Vernonia amygdalina root extracts are frequently used in Ethiopian ...
DOI:
10.1186/s12906-017-2056-x

17. Purification and MIC analysis of antimicrobial proteins from Cucumis sativus L. seeds

Author:
Al Akeel, Raid; Mateen, Ayesha; Alharbi, KhalidK.; Alyousef, AbdullahA.; Al-Mandeel, HazemM.; Syed, Rabbani
Source:
BMC complementary and alternative medicine 2018 v.18 no.1 pp. 1-121
ISSN:
1472-6882
Subject:
Ayurvedic medicine; alternative medicine; herbal medicines,   etc   ; Cucumis sativus; Escherichia coli; anti-infective agents; antibacterial properties; antimicrobial peptides; antimicrobial proteins; bacteria; cetyltrimethylammonium bromide; citrates; cucumbers; dialysis; foodborne illness; ion exchange chromatography; pH; seeds; sodium phosphate; spoilage;     Show all 20 Subjects
Abstract:
... BACKGROUND: Cucumis sativus L. (cucumber), from the family Cucurbitaceae, is a therapeutic plant with various pharmacological benefits, broadly utilized as a part of complementary medicine (e.g., Unani, Ayurveda, Siddha, and Traditional Chinese). In light of past research discoveries, this plant had been chosen to consider its potential antibacterial action. METHODS: Extracts were purified by dial ...
DOI:
10.1186/s12906-018-2176-y

18. Antioxidant capacities and total phenolic contents of 20 polyherbal remedies used as tonics by folk healers in Phatthalung and Songkhla provinces, Thailand

Author:
Chanthasri, Wipawee; Puangkeaw, Nuntitporn; Kunworarath, Nongluk; Jaisamut, Patcharawalai; Limsuwan, Surasak; Maneenoon, Katesarin; Choochana, Piyapong; Chusri, Sasitorn
Source:
BMC complementary and alternative medicine 2018 v.18 no.1 pp. 1-73
ISSN:
1472-6882
Subject:
alternative medicine; traditional medicine,   etc   ; 2,2-diphenyl-1-picrylhydrazyl; active ingredients; antioxidant activity; cytotoxicity; flavonoids; free radical scavengers; functional foods; health claims; industry; phytopharmaceuticals; superoxide anion; Thailand;     Show all 14 Subjects
Abstract:
... BACKGROUND: Uses of polyherbal formulations have played a major role in traditional medicine. The present study is focused on the formulations used in traditional Thai folkloric medicine as tonics or bracers. Twenty documented polyherbal mixtures, used as nourishing tonics by the folk healers in Phatthalung and Songkhla provinces in southern Thailand, are targeted. Despite traditional health claim ...
DOI:
10.1186/s12906-018-2131-y

19. Development and validation of HPTLC fingerprints of three species of Alpinia with biomarker Galangin

Author:
Upadhye, AnuradhaS.; Rajopadhye, Anagha; Dias, Lourelle
Source:
BMC complementary and alternative medicine 2018 v.18 no.1 pp. 1-16
ISSN:
1472-6882
Subject:
alternative medicine; medicine,   etc   ; Alpinia galanga; acetic acid; adulterated products; biomarkers; densitometry; ethyl acetate; guidelines; hexane; medicinal properties; quality control; quantitative analysis; rhizomes; silica gel; thin layer chromatography;     Show all 16 Subjects
Abstract:
... BACKGROUND: Alpinia galanga (L.) Willd. commonly called as Rasna, Greater galangal or Kulinjan is a medicinally important rhizome used in Indian traditional system of medicine to cure a number of ailments. A. galanga is the main source of a galangin -a medicinally important flavanol which has a number of pharmacological properties viz. anti-mutagenic, and anti-inflammatory. Due to the high demand ...
DOI:
10.1186/s12906-017-2033-4

20. Isolation and characterization of olfactory ecto-mesenchymal stem cells from eight mammalian genera

Author:
Veron, AntoineD.; Bienboire-Frosini, Cécile; Feron, François; Codecasa, Elisa; Deveze, Arnaud; Royer, Dany; Watelet, Paul; Asproni, Pietro; Sadelli, Kevin; Chabaud, Camille; Stamegna, Jean-claude; Fagot, Joël; Khrestchatisky, Michel; Cozzi, Alessandro; Roman, FrançoisS.; Pageat, Patrick; Mengoli, Manuel; Girard, StéphaneD.
Source:
BMC veterinary research 2018 v.14 no.1 pp. 1-17
ISSN:
1746-6148
Subject:
medicine; veterinary medicine,   etc   ; Microcebus; autografting; biopsy; clinical trials; dogs; ethics; explants; horses; humans; mice; models; mucosa; nasal cavity; rabbits; rats; sheep; stem cells;     Show all 19 Subjects
Abstract:
... BACKGROUND: Stem cell-based therapies are an attractive option to promote regeneration and repair defective tissues and organs. Thanks to their multipotency, high proliferation rate and the lack of major ethical limitations, “olfactory ecto-mesenchymal stem cells” (OE-MSCs) have been described as a promising candidate to treat a variety of damaged tissues. Easily accessible in the nasal cavity of ...
DOI:
10.1186/s12917-018-1342-2