PubAg

Main content area

You searched for: Subject "microarray technology" Remove constraint Subject: "microarray technology"
Start Over

Search

10,259  Search Results

« Previous | 1 - 20 of 10,259 |
Number of results to display per page

Search Results

1. Evaluation of Mass Sensitive Micro-Array biosensors for their feasibility in multiplex detection of low molecular weight toxins using mycotoxins as model compounds

Author:
Nolan, P.; Auer, S.; Spehar, A.; Oplatowska-Stachowiak, M.; Campbell, K.
Source:
Talanta 2021 v.222 pp. 121521
ISSN:
0039-9140
Subject:
microarray technology,   etc   ; Fusarium; T-2 toxin; antibodies; biosensors; cost effectiveness; feeds; food security; food supply chain; fumonisin B1; models; molecular weight; monitoring; rapid methods; screening; small cereal grains; supply chain; zearalenone;     Show all 18 Subjects
Abstract:
... Mycotoxins produced by Fusarium species including trichothecenes, zearalenone and fumonisins, can co-contaminate food and feed throughout the supply chain, including cereal grains and animal feeds. There is an increasing demand to enhance global food security by improving the monitoring of mycotoxins throughout our food supply chain. For time and cost-efficient analysis, rapid tests capable of det ...
DOI:
10.1016/j.talanta.2020.121521

2. Mini-pillar microarray for individually electrochemical sensing in microdroplets

Author:
Song, Yongchao; Xu, Tailin; Xiu, Jidong; Zhang, Xueji
Source:
Biosensors & bioelectronics 2020 v.149 pp. 111845
ISSN:
0956-5663
Subject:
microarray technology,   etc   ; adhesion; biomarkers; biosensors; deformation; drugs; electrochemistry; electrodes; glucose;     Show all 9 Subjects
Abstract:
... High throughput and high sensitivity are two important aspects in multiple biomarker recognition, drug discovery and relevant biochemical sensing. Here, we integrate mini-pillar microarray with the circuit components toward high-throughput individual electrochemical sensing in microdroplets. On such droplet-microarray-based electrochemical platform, the high adhesion of the mini-pillar can hold a ...
DOI:
10.1016/j.bios.2019.111845

3. Immunoassays on thiol-ene synthetic paper generate a superior fluorescence signal

Author:
Guo, Weijin; Vilaplana, Lluisa; Hansson, Jonas; Marco, M.-Pilar; van der Wijngaart, Wouter
Source:
Biosensors & bioelectronics 2020 v.163 pp. 112279
ISSN:
0956-5663
Subject:
microarray technology,   etc   ; European Union; antibiotics; biosensors; detection limit; enrofloxacin; fluorescence; glass; immunoaffinity chromatography; immunoassays; whole milk;     Show all 11 Subjects
Abstract:
... The fluorescence-based detection of biological complexes on solid substrates is widely used in microarrays and lateral flow tests. Here, we investigate thiol-ene micropillar scaffold sheets (“synthetic paper”) as the solid substrate in such assays. Compared to state-of-the-art glass and nitrocellulose substrates, assays on synthetic paper provide a stronger fluorescence signal, similar or better r ...
DOI:
10.1016/j.bios.2020.112279

4. Enzymatic modular synthesis and microarray assay of poly-N-acetyllactosamine derivatives

Author:
Chen, Congcong; Wang, Shuaishuai; Gadi, Madhusudhan Reddy; Zhu, He; Liu, Fei; Liu, Chang-Cheng; Li, Lei; Wang, Fengshan; Ling, Peixue; Cao, Hongzhi
Source:
Chemical communications 2020 v.56 no.55 pp. 7549-7552
ISSN:
1364-548X
Subject:
microarray technology,   etc   ; binding capacity; binding proteins; chemical compounds; chemical reactions; polysaccharides;     Show all 6 Subjects
Abstract:
... A facile enzymatic modular assembly strategy for the preparative-scale synthesis of poly-N-acetyllactosamine (poly-LacNAc) glycans with varied lengths and designed sialylation and/or fucosylation patterns is described. These glycans were printed as a microarray to investigate their interactions with a panel of glycan binding proteins (GBPs). Binding affinities revealed that the avidity of GBPs cou ...
DOI:
10.1039/d0cc03268a

5. Network aggregation improves gene function prediction of grapevine gene co-expression networks

Author:
Wong, Darren C. J.
Source:
Plant molecular biology 2020 v.103 no.4-5 pp. 425-441
ISSN:
0167-4412
Subject:
microarray technology,   etc   ; Vitis; data collection; genes; genomics; meta-analysis; prediction; sequence analysis; transcription (genetics); transcriptome;     Show all 10 Subjects
Abstract:
... KEY MESSAGE: Aggregation across multiple networks highlights robust co-expression interactions and improves the functional connectivity of grapevine gene co-expression networks. In recent years, the rapid accumulation of transcriptome datasets from diverse experimental conditions has enabled the widespread use of gene co-expression network (GCN) analysis in plants. In grapevine, GCN analysis has s ...
DOI:
10.1007/s11103-020-01001-2

6. Folate-Modified Photoelectric Responsive Polymer Microarray as Bionic Artificial Retina to Restore Visual Function

Author:
Yu, Zheng-Hang; Chen, Wei-Jian; Liu, Xi; Xia, Qiu-Yu; Yang, Yi-Nuo; Dong, Mei; Liu, Jia-Hao; Guan, Huai-Jin; Sun, Cheng; Feng, Fu-De; Shen, Qun-Dong
Source:
ACS applied materials & interfaces 2020 v.12 no.25 pp. 28759-28767
ISSN:
1944-8252
Subject:
microarray technology,   etc   ; electrophysiology; folic acid; fullerene; nerve tissue; neurons; photoreceptors; photosensitivity; phototransduction; polymers; rats; retina; surgery;     Show all 13 Subjects
Abstract:
... A high-optical-resolution artificial retina system that accurately communicates with the optic nerve is the main challenge in the modern biological science and bionic field. Here, we developed a bionic artificial retina possessing phototransduction “cells” with measurements even smaller than that of the neural cells. Using the technique of micrometer processing, we constructed a pyramid-shape peri ...
DOI:
10.1021/acsami.0c04058

7. Expression of the hippo signalling pathway effector YAP during canine epidermal tumourigenesis

Author:
Sanz Ressel, Berenice Liyare; Massone, Adriana Raquel; Barbeito, Claudio Gustavo
Source:
Research in veterinary science 2020 v.130 pp. 93-97
ISSN:
0034-5288
Subject:
microarray technology,   etc   ; carcinogenesis; dogs; immunohistochemistry; papilloma; patients; signal transduction; squamous cell carcinoma; therapeutics;     Show all 9 Subjects
Abstract:
... Cutaneous papilloma (CP) and cutaneous squamous cell carcinoma (CSCC) are frequent epidermal tumours in dogs. In this regard, the study of the deregulated activity of signalling molecules during the epidermal tumourigenesis process could be the basis for the development of novel molecular mechanism-based antitumour treatments for CP and CSCC canine patients. Recent evidence suggests that the devel ...
DOI:
10.1016/j.rvsc.2020.03.006

8. Establishment of a 1, 4, 7, 10-tetraazacyclododecane-1,4,7,10-tetraacetic acid mono-N-hydroxysuccinimide ester (DOTA–NHS–ester) based lectin microarray for efficiently detecting serum glycans in gastric cancers

Author:
Gao, Yi; Li, Song-Guo; Liu, Qian; Liu, Sheng-Sheng; Ye, Lei; Song, Zi-Jian; Du, Wei-Dong
Source:
Analytical biochemistry 2020 v.597 pp. 113686
ISSN:
0003-2697
Subject:
microarray technology,   etc   ; biomarkers; blood serum; crosslinking; geometry; gold; immunity; lectins; patients; polysaccharides; stomach neoplasms; thiols;     Show all 12 Subjects
Abstract:
... Development of cancers is involved in changes of a variety of glycans. Lectin microarray is one of the most powerful methodologies for investigation of glycan alterations in biological samples with its advantages of high through-put, selectivity and specificity of the technique. However, utilization of lectin microarrays available commercially keeps of great challenges. In this study, we took use ...
DOI:
10.1016/j.ab.2020.113686

9. Saponin extract of Baihe - Zhimu Tang ameliorates depression in chronic mild stress rats

Author:
Jia, Dan; Dou, Yonghui; He, Yongshi; Zhou, Xinxin; Gao, Ying; Ma, Min; Wu, Zhengzhi; Li, Weimin
Source:
Journal of functional foods 2020 v.68 pp. 103905
ISSN:
1756-4646
Subject:
microarray technology,   etc   ; Oriental traditional medicine; animal models; apoptosis; neurons; neuroprotective effect; neurotransmitters; rats; saponins;     Show all 9 Subjects
Abstract:
... In Traditional Chinese Medicine (TCM), the prescription Baihe - Zhimu Tang has been using to treat depression for hundreds of years. However, its underlying mechanism is still unclear. Saponin compounds extracted from TCM have been reported to exert antidepressant-like effect. In present study, we investigated the efficacy and mechanism of Saponin extract from Baihe - Zhimu Tang (SBZT) in treating ...
DOI:
10.1016/j.jff.2020.103905

10. Controlling Microarray Feature Spreading and Response Stability on Porous Silicon Platforms by Using Alkene-Terminal Ionic Liquids and UV Hydrosilylation

Author:
Trivedi, Shruti; Ravula, Sudhir; Baker, Gary A.; Pandey, Siddharth; Bright, Frank V.
Source:
Langmuir 2020 v.36 no.19 pp. 5474-5482
ISSN:
1520-5827
Subject:
microarray technology,   etc   ; Fourier transform infrared spectroscopy; image analysis; ionic liquids; photochemistry; photoluminescence; silicon; toluene; vapors;     Show all 9 Subjects
Abstract:
... In an attempt to develop reversible sensors based on ionic liquid/porous silicon (IL/pSi) platforms, we introduce an approach using task-specific, alkene-terminal ILs (AT-ILs) for direct grafting to the hydrogen-passivated as prepared-pSi (ap-pSi) surface via UV-hydrosilylation to address previous shortcomings associated with IL pattern impermanence (i.e., spread). By employing photoluminescence e ...
DOI:
10.1021/acs.langmuir.0c00106

11. Aberrant Expression of E-cadherin/β-catenin During Epidermal Tumourigenesis in Dogs

Author:
Sanz Ressel, B.L.; Massone, A.R.; Barbeito, C.G.
Source:
Journal of comparative pathology 2020 v.176 pp. 1-9
ISSN:
0021-9975
Subject:
microarray technology,   etc   ; adherens junctions; beta catenin; cadherins; carcinogenesis; carcinoma; dogs; immunohistochemistry; signal transduction;     Show all 9 Subjects
Abstract:
... Clinically relevant epidermal tumours in dogs include cutaneous papillomas (CPs) and cutaneous squamous cell carcinomas (CSCCs). The development of CPs and CSCCs involves dysregulation in expression of E-cadherin/β-catenin; however, knowledge about the contribution of these molecules to epidermal tumourigenesis in dogs is limited. This study examined the immunohistochemical expression pattern of E ...
DOI:
10.1016/j.jcpa.2020.01.006

12. Food allergomics based on high-throughput and bioinformatics technologies

Author:
Wang, Chong; Wang, Yanbo; Liu, Guangming; Fu, Linglin
Source:
Food research international 2020 v.130 pp. 108942
ISSN:
0963-9969
Subject:
microarray technology,   etc   ; bioinformatics; food allergens; food allergies; food safety; immunoblotting; phages;     Show all 7 Subjects
Abstract:
... Food allergy is a serious food safety problem worldwide, and the investigation of food allergens is the foundation of preventing and treating them, but relevant knowledge is far from sufficient. With the advent of the “big data era”, it has been possible to investigate food allergens by high-throughput methods, proposing the concept of allergomics. Allergomics is the discipline studying the repert ...
DOI:
10.1016/j.foodres.2019.108942

13. Stimuli-Responsive Microarray Films for Real-Time Sensing of Surrounding Media, Temperature, and Solution Properties via Diffraction Patterns

Author:
Zhang, Jiaxin; Gai, Meiyu; Ignatov, Aleksei V.; Dyakov, Sergey A.; Wang, Jing; Gippius, Nikolay A.; Frueh, Johannes; Sukhorukov, Gleb B.
Source:
ACS applied materials & interfaces 2020 v.12 no.16 pp. 19080-19091
ISSN:
1944-8252
Subject:
microarray technology,   etc   ; calcium; equipment; ions; lactones; microstructure; pH; photons; polymers; temperature;     Show all 10 Subjects
Abstract:
... Stimuli-responsive polymers have attracted increasing attention over the years due to their ability to alter physiochemical properties upon external stimuli. However, many stimuli-responsive polymer-based sensors require specialized and expensive equipment, which limits their applications. Here an inexpensive and portable sensing platform of novel microarray films made of stimuli-responsive polyme ...
DOI:
10.1021/acsami.0c05349

14. Plasmonic Gold Templates Enhancing Single Cell Lipidomic Analysis of Microorganisms

Author:
Shanta, Peter V.; Li, Bochao; Stuart, Daniel D.; Cheng, Quan
Source:
Analytical chemistry 2020 v.92 no.9 pp. 6213-6217
ISSN:
1520-6882
Subject:
microarray technology,   etc   ; algae; atrazine; ecotoxicology; fluorescence; glycerol; ionization; lipid composition; lipids; microorganisms;     Show all 10 Subjects
Abstract:
... Single cell lipid profiling is a powerful tool to connect membrane composition and its changes within individual cells to specific biochemical functions or stimuli, but current approaches are inadequate due to the complex nature of the cells and technical limitation in analysis. Herein we report a new method with plasmonic substrates capable of cell localization and enhanced lipid ionization throu ...
DOI:
10.1021/acs.analchem.9b05285

15. Aminophenylboronic Acid-Functionalized Thorny-Trap-Shaped Monolayer Microarray for Efficient Capture and Release of Circulating Tumor Cells

Author:
Jin, Rongrong; Wang, Jiaxi; Gao, Mingxia; Zhang, Xiangmin
Source:
Analytical chemistry 2020 v.92 no.4 pp. 3403-3408
ISSN:
1520-6882
Subject:
microarray technology,   etc   ; binding sites; blood sampling; ligands; nanorods; neoplasm cells; neoplasms; phenylboronic acids; sialic acid; topology;     Show all 10 Subjects
Abstract:
... An aminophenylboronic acid (APBA)-functionalized thorny-trap-shaped monolayer microarray as a 3D fractal structures’ substrate was fabricated to capture and release circulating tumor cells (CTCs) efficiently. The microarray can not only trap cells inside by microbowls but also enhance the interaction between cell and substrate by providing more binding sites and facilitating the spread of cell fil ...
DOI:
10.1021/acs.analchem.9b05486

16. A nonparametric feature screening method for ultrahigh-dimensional missing response

Author:
Li, Xiaoxia; Tang, Niansheng; Xie, Jinhan; Yan, Xiaodong
Source:
Computational statistics & data analysis 2019
ISSN:
0167-9473
Subject:
microarray technology,   etc   ; B-cell lymphoma; screening;     Show all 3 Subjects
Abstract:
... This paper addresses the feature screening issue for ultrahigh-dimensional data with responses missing at random. A novel nonparametric feature screening procedure is developed to identify the important features via the conditionally imputing marginal Spearman rank correlation. The proposed nonparametric screening approach has several desirable merits. First, it is nonparametric without assuming a ...
DOI:
10.1016/j.csda.2019.106828

17. Acoustopipetting: Tunable Nanoliter Sample Dispensing Using Surface Acoustic Waves

Author:
Castro, Jasmine O.; Ramesan, Shwathy R.; Dang, Huy D.; Rezk, Amgad R.; Yeo, Leslie Y.
Source:
Analytical chemistry 2019 v.91 no.9 pp. 5621-5628
ISSN:
1520-6882
Subject:
microarray technology,   etc   ; automation; drugs; liquids; sounds; toxicology;     Show all 6 Subjects
Abstract:
... We seek to demonstrate a robust, low-cost, and user-friendly acoustomicrofluidic platform that facilitates rapid, reproducible, and precise nanoliter sample dispensing. The solid-state chipscale platform exploits the unprecedented acceleration arising from high-frequency nanoelectromechanical vibrations, on the order of 10 million g, to jet the sample and hence generate a liquid bridge that spans ...
DOI:
10.1021/acs.analchem.8b05319

18. A regression framework for assessing covariate effects on the reproducibility of high‐throughput experiments

Author:
Li, Qunhua; Zhang, Feipeng
Source:
Biometrics 2018 v.74 no.3 pp. 803-813
ISSN:
0006-341X
Subject:
microarray technology,   etc   ; biometry; models;     Show all 3 Subjects
Abstract:
... The outcome of high‐throughput biological experiments is affected by many operational factors in the experimental and data‐analytical procedures. Understanding how these factors affect the reproducibility of the outcome is critical for establishing workflows that produce replicable discoveries. In this article, we propose a regression framework, based on a novel cumulative link model, to assess th ...
DOI:
10.1111/biom.12832
PubMed:
29192968
PubMed Central:
PMC5975112

19. Large-scale analysis of zebrafish (Danio rerio) transcriptomes identifies functional modules associated with phenotypes

Author:
Liu, Wei; Wang, Yanan
Source:
Marine genomics 2020 v.53 pp. 100770
ISSN:
1874-7787
Subject:
microarray technology,   etc   ; Danio rerio; cell cycle; gene expression; genes; medicine; models; phenotype; tissues; toxicology; transcriptome; world wide web;     Show all 12 Subjects
Abstract:
... Zebrafish (Danio rerio) is an excellent model for biomedicine research due to its genetic accessibility and optical transparency. A large number of microarray based transcriptomes of zebrafish have been profiled in various cell types, tissues, development stages, toxicological exposures and other conditions. However, there is still no easy-to-use web tool to explore those precious data. We downloa ...
DOI:
10.1016/j.margen.2020.100770

20. miR-1278 sensitizes nasopharyngeal carcinoma cells to cisplatin and suppresses autophagy via targeting ATG2B

Author:
Zhao, Yingying; Wang, Peihua; Wu, Qingwei
Source:
Molecular and cellular probes 2020 v.53 pp. 101597
ISSN:
0890-8508
Subject:
microarray technology,   etc   ; autophagy; carcinoma; cell lines; cisplatin; data collection; drug therapy; gain-of-function mutation; genes; microRNA; neoplasm cells; tissues;     Show all 12 Subjects
Abstract:
... Chemoresistance to cisplatin (DDP) has become a dominating obstacle to the successful treatment of nasopharyngeal carcinoma (NPC). Recently, accumulating data support the tenet that microRNAs (miRNAs) function as new crucial regulators of diverse biological processes, including chemoresistance. In this study, the miRNA expression profiles in NPC were first analyzed using miRNA microarray dataset. ...
DOI:
10.1016/j.mcp.2020.101597