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1. The piRNA response to BmNPV infection in the silkworm fat body and midgut

Author:
Min Feng; Anna Kolliopoulou; Yao‐Hong Zhou; Shi‐Gang Fei; Jun‐Ming Xia; Luc Swevers; Jing‐Chen Sun
Source:
Insect science 2021 v.28 no.3 pp. 662-679
ISSN:
1672-9609
Subject:
midgut,   etc   ; Bombyx mori nucleopolyhedrovirus; fat body; industry; silkworms; transposons;     Show all 6 Subjects
Abstract:
... Bombyx mori nucleopolyhedrovirus (BmNPV) is a DNA virus that causes huge losses to the silkworm industry but the piRNA responses during BmNPV infection in the silkworm remain uninvestigated. Here, silkworm piRNA profiles of uninfected and BmNPV‐infected fat body and midgut were determined by high‐through sequencing in the early stages of BmNPV infection. A total of 2675 and 3396 genome‐derived ...
DOI:
10.1111/1744-7917.12796

2. Defining cell types and lineage in the Drosophila midgut using single cell transcriptomics

Author:
Ruei-Jiun Hung; Joshua Shing Shun Li; Yifang Liu; Norbert Perrimon
Source:
Current opinion in insect science 2021 v.47 pp. 12-17
ISSN:
2214-5745
Subject:
midgut,   etc   ; Drosophila; cell proliferation; gene expression; histology; homeostasis; insects; microorganisms; stem cells; transcriptomics;     Show all 10 Subjects
Abstract:
... The Drosophila midgut has emerged in recent years as a model system to study stem cell renewal and differentiation and tissue homeostasis. Histological, genetic and gene expression studies have provided a wealth of information on gut cell types, regionalization, genes and pathways involved in cell proliferation and differentiation, stem cell renewal, and responses to changes in environmental ...
DOI:
10.1016/j.cois.2021.02.008

3. Midgut bacterial diversity of a leaf-mining beetle, Dactylispa xanthospila (Gestro) (Coleoptera: Chrysomelidae: Cassidinae)

Author:
Lixing Cui; Qingyun Guo; Xuexiong Wang; Kevin Jan Duffy; Xiaohua Dai
Source:
Biodiversity data journal 2021 v.9 pp. e62843
ISSN:
1314-2828
Subject:
midgut,   etc   ; Bacteroidetes; Caulobacteraceae; Chrysomelidae; Comamonadaceae; Enterobacteriaceae; Firmicutes; Rhizobiaceae; Sphingomonadaceae; amino acid metabolism; bacterial communities; biodiversity; carbohydrate metabolism; vitamin metabolism;     Show all 14 Subjects
Abstract:
... Microorganisms play an essential role in the growth and development of numerous insect species. In this study, the total DNA from the midgut of adults of Dactylispa xanthospila were isolated and bacterial 16S rRNA sequenced using the high-throughput Illumina MiSeq platform. Then, the composition and diversity of the midgut bacterial community were analysed with QIIME2. The results showed ...
DOI:
10.3897/BDJ.9.e62843

4. Morphological, Histological and Ultrastructural Characterisation of Culex pipiens (Diptera: Culicidae) Larval Midgut

Author:
A.A. Al-Doaiss; F.A. Al-Mekhlafi; N.M. Abutaha; L.A. Al-Keridis; A.A. Shati; M.A. Al-Kahtani; M.Y. Alfaifi
Source:
African entomology 2021 v.29 no.1 pp. 274-288
ISSN:
1021-3589
Subject:
Culex pipiens; abdomen; basement membrane; digestive tract; entomology; foregut; head; hemolymph; hindgut; histology; insecticide resistance; instars; lysosomes; microvilli; mitochondria; mosquito control; peritrophic membrane; rough endoplasmic reticulum; thorax; transmission electron microscopy; Saudi Arabia
Abstract:
... Culex pipiens (Cx. pipiens) or common house mosquito is the most widely distributed species worldwide, including Saudi Arabia. The current study examined morphological, histological, and ultrastructural features of midgut epithelium of fourth instar larvae of Cx. pipiens. Findings provide a basis for research on insecticide resistance and mosquito control. The morphological, histological ...
DOI:
10.4001/003.029.0274

5. Gut-specific arylphorin mediates midgut regenerative response against Cry-induced damage in Achaea janata

Author:
Narender K. Dhania; Vinod K. Chauhan; Dasari Abhilash; Vivek Thakur; R.K. Chaitanya; Shourya Dutta-Gupta; Aparna Dutta-Gupta
Source:
Comparative biochemistry and physiology 2021 v.255 pp. 110600
ISSN:
1096-4959
Subject:
midgut,   etc   ; Achaea janata; actin; antibodies; biopesticides; cell proliferation; computer simulation; cross reaction; cyclins; cytoskeleton; epithelium; fluorescence; fluorescence microscopy; fluorescent antibody technique; humans; insect resistance; insects; microvilli; mitosis; pest control; phylogeny; poisoning; stem cells; toxins;     Show all 24 Subjects
Abstract:
... Development of insect resistance to biopesticides is a current and pertinent global issue. Earlier, it was established that lepidopteran larvae can recover from Bt intoxication via a midgut regenerative response and subsequently generate resistance. Molecular aspects of restoration of the midgut integrity following toxin exposure are emerging recently. In the present study, we bring out ...
DOI:
10.1016/j.cbpb.2021.110600

6. Low METTL3 level in midgut of the Bombyx mori inhibit the proliferation of nucleopolyhedrovirus

Author:
Peng Xue; Tao Jiang; Juan Zhu; Meixian Wang; Qiaoling Zhao; Jinshan Huang; Shunming Tang; Xingjia Shen
Source:
Journal of Asia-Pacific entomology 2021 v.24 no.1 pp. 42-49
ISSN:
1226-8615
Subject:
midgut,   etc   ; Bombyx mori; Bombyx mori nucleopolyhedrovirus; entomology; genes; infection; larvae; nucleocapsid proteins; silkworms; viruses;     Show all 10 Subjects
Abstract:
... knockdown of METTL3in vitro were quantified to identify the effect of m⁶A modification on BmNPV. BmNPV firstly infects the larval midgut in case of oral infection. Subsequently, to clarify the relationship between m⁶A modification and resistance of the silkworm to BmNPV, we detected the expression levels of m⁶A-modification-related genes invivo before and after infection of BmNPV. The results indicated ...
DOI:
10.1016/j.aspen.2020.10.015

7. Overexpression of Activated AMPK in the Anopheles stephensi Midgut Impacts Mosquito Metabolism, Reproduction and Plasmodium Resistance

Author:
Chioma Oringanje; Lillian R. Delacruz; Yunan Han; Shirley Luckhart; Michael A. Riehle
Source:
Genes 2021 v.12 no.1 pp. -
ISSN:
2073-4425
Subject:
midgut,   etc   ; AMP-activated protein kinase; Anopheles stephensi; Plasmodium falciparum; blood meal; egg production; energy; females; genetically modified organisms; glycogen; homeostasis; homozygosity; innate immunity; metabolism; mitochondria; mosquito vectors; transgenes; trehalose;     Show all 18 Subjects
Abstract:
... Mitochondrial integrity and homeostasis in the midgut are key factors controlling mosquito fitness and anti-pathogen resistance. Targeting genes that regulate mitochondrial dynamics represents a potential strategy for limiting mosquito-borne diseases. AMP-activated protein kinase (AMPK) is a key cellular energy sensor found in nearly all eukaryotic cells. When activated, AMPK inhibits anabolic ...
DOI:
10.3390/genes12010119

8. Midgut aminopeptidase N expression profile in castor semilooper (Achaea janata) during sublethal Cry toxin exposure

Author:
Vinod K. Chauhan; Narender K. Dhania; Vadthya Lokya; Bhoopal Bhuvanachandra; Kollipara Padmasree; Aparna Dutta-Gupta
Source:
Journal of biosciences 2021 v.46 no.1 pp. 29
ISSN:
0250-5991
Subject:
midgut,   etc   ; ABC transporters; Achaea janata; Bacillus thuringiensis; absorption; alkaline phosphatase; cadherins; digestion; gene expression regulation; immunity; membrane alanyl aminopeptidase; microvilli; proteinases; proteomics; sequence homology; toxicity; toxins; transcriptomics;     Show all 18 Subjects
Abstract:
... The midgut of lepidopteran larvae is a multifunctional tissue that performs roles in digestion, absorption, immunity, transmission of pathogens and interaction with ingested various molecules. The proteins localized at the inner apical brush border membrane are primarily digestive proteases, but some of them, like aminopeptidase N, alkaline phosphatase, cadherins, ABC transporter C2, etc ...
DOI:
10.1007/s12038-021-00148-4

9. Identification and evaluation of midgut protein RL12 of Dermacentor silvarum interacting with Anaplasma ovis VirD4

Author:
Naveed Iqbal; Muhammad Uzair Mukhtar; Jifei Yang; Qingli Niu; Zhi Li; Shuaiyang Zhao; Yaru Zhao; Guiquan Guan; Zhijie Liu; Hong Yin
Source:
Ticks and tick-borne diseases 2021 v.12 no.3 pp. 101677
ISSN:
1877-959X
Subject:
midgut,   etc   ; Anaplasma ovis; Dermacentor; Gram-negative bacteria; anaplasmosis; animal pathogenic bacteria; arthropod proteins; biogenesis; cDNA libraries; disease vectors; glutathione transferase; ribosomal proteins; sheep diseases; signal transduction; ticks; type IV secretion system;     Show all 16 Subjects
Abstract:
... Anaplasma ovis, a tick-borne intra-erythrocytic Gram-negative bacterium, is a causative agent of ovine anaplasmosis. It is known that Dermacentor ticks act as biological vectors for A. ovis. VirD4 is the machine component of Type IV Secretion System of A. ovis. To better understand the pathogen-vector interaction, VirD4 was used as a bait protein for screening midgut proteins of Dermacentor ...
DOI:
10.1016/j.ttbdis.2021.101677

10. Midgut Genes Knockdown by Oral dsRNA Administration Produces a Lethal Effect on Cotton Boll Weevil

Author:
Ricardo Salvador; José M. Niz; Pablo A. Nakaya; Analía Pedarros; H. Esteban Hopp
Source:
Neotropical entomology 2021 v.50 no.1 pp. 121-128
ISSN:
1519-566X
Subject:
midgut,   etc   ; Anthonomus grandis; Neotropics; RNA interference; alpha-amylase; biological control; cotton; cytochrome P-450; death; double-stranded RNA; entomology; flower buds; genes; ingestion; insecticides; mortality; nucleotide sequences; oral administration; pests;     Show all 19 Subjects
Abstract:
... demonstrated RNAi responses depend on life stages and target genes. The dsRNA ingestion was capable of providing knockdown mRNA levels in cotton boll weevil midgut and this effect was significantly higher in the larval stage. In this study, we present a new report of silencing of midgut genes in A. grandis larva induced by continuously feeding with dsRNA. This potential new tool should be further evaluated ...
DOI:
10.1007/s13744-020-00819-1

11. Triatoma infestans susceptibility to different Trypanosoma cruzi strains: parasite development and early escape from anterior midgut

Author:
Larissa F. Paranaiba; Rodrigo P. Soares; Alessandra A. Guarneri
Source:
Parasitology 2021 v.148 no.3 pp. 295-301
ISSN:
1469-8161
Subject:
midgut,   etc   ; Triatoma infestans; Trypanosoma cruzi; digestive tract; epimastigotes; parasites; parasitology; rectum; trypomastigotes;     Show all 9 Subjects
Abstract:
... The escape kinetics from the anterior midgut (AM) of Trypanosoma cruzi during the initial steps of infection was assessed in Triatoma infestans, as well as its ability to survive migration in the digestive tract of the vector. All the four strains evaluated survived and reached variable parasite densities. After 49–50 days, YuYu [discrete typing units (DTU) I] strain reached the highest parasite ...
DOI:
10.1017/S0031182020001699

12. Transcriptomic and proteomic analysis of the underlying mechanisms of digestion of triacylglycerols and phosphatides and absorption and fate of fatty acids along the midgut of Musca domestica

Author:
Ignacio G. Barroso; Christiane Cardoso; Clelia Ferreira; Walter R. Terra
Source:
Comparative biochemistry and physiology 2021 v.39 pp. 100826
ISSN:
1744-117X
Subject:
midgut,   etc   ; Musca domestica; absorption; acyl coenzyme A; alpha-glycerophosphoric acid; carboxylic ester hydrolases; diacylglycerols; digestion; energy; larvae; ligases; phospholipases; proteomics; sequence analysis; transcriptomics; triacylglycerols;     Show all 16 Subjects
Abstract:
... midgut was evaluated by RNA-seq. Some of the codified proteins were identified in midgut microvillar-enriched membrane by proteomics. 1PLIPs are the most expressed PLIPs, mainly in anterior midgut whereas 2PLIPs, and BPLIP in middle and posterior midgut, and ALIPs between middle and posterior regions. Absorption of FAs is putatively accomplished by proteins involved in FA activation (acyl-CoA ...
DOI:
10.1016/j.cbd.2021.100826

13. Synthesis and Photoactivated Toxicity of 2-Thiophenylfuranocoumarin Induce Midgut Damage and Apoptosis in Aedes aegypti Larvae

Author:
Jiecheng Wu; Lanying Wang; Yunfei Zhang; Shujing Zhang; Shakil Ahmad; Yanping Luo
Source:
Journal of agricultural and food chemistry 2021 v.69 no.3 pp. 1091-1106
ISSN:
1520-5118
Subject:
midgut,   etc   ; Aedes aegypti; apoptosis; bromination; esterification; food chemistry; histopathology; instars; intestines; mechanism of action; metabolites; mitochondria; oxidative stress; photosensitivity; psoralens; reactive oxygen species; toxicity; ultraviolet radiation;     Show all 18 Subjects
Abstract:
... excellent photosensitive activity. Three Iy concentrations (LC₂₅, LC₅₀, and LC₇₅) were used to treat the fourth instar larvae of Aedes aegypti (A. aegypti). The photoactivated toxicity, sublethal dose, mitochondrial dysfunction, oxidative stress level, intestinal barrier dysfunction, and apoptosis were studied. The results showed that Iy induced reactive oxygen species (ROS) production in midgut cells ...
DOI:
10.1021/acs.jafc.0c07237

14. Analyses of microRNAs and transcriptomes in the midgut of Spodoptera litura feeding on Brassica juncea

Author:
Xiao‐Peng Zou; Yi‐Guang Lin; Yong‐Jie Cen; Kang Ma; Bin‐Bin Qiu; Qi‐Li Feng; Si‐Chun Zheng
Source:
Insect science 2021 v.28 no.2 pp. 533-547
ISSN:
1672-9609
Subject:
midgut,   etc   ; Brassica juncea; Spodoptera litura; cytochrome P-450; digestion; esterases; glutathione transferase; insects; microRNA; pest control; pests; proteinases; quantitative polymerase chain reaction; transcriptome; uridine;     Show all 15 Subjects
Abstract:
... Spodoptera litura is a destructive agricultural pest in tropical and subtropical areas. Understanding the molecular mechanisms of S. litura adaptation to its preferred host plants may help identify target genes useful for pest control. We used high‐throughput sequencing to characterize the expression patterns of messenger RNAs (mRNAs) and microRNAs (miRNAs) in the midgut of S. litura fed ...
DOI:
10.1111/1744-7917.12779

15. Sestrin protects Drosophila midgut from mercury chloride-induced damage by inhibiting oxidative stress and stimulating intestinal regeneration

Author:
Zhi Chen; Wen Zhang; Fen Wang; Ren Mu; Di Wen
Source:
Comparative biochemistry and physiology 2021 v.248 pp. 109083
ISSN:
1532-0456
Subject:
midgut,   etc   ; Drosophila melanogaster; apoptosis; cell division; genes; glutathione transferase; heavy metals; immunohistochemistry; intestines; mercury; neurons; oxidative stress; reactive oxygen species; stem cells; stress response; superoxide dismutase; therapeutics; tissue repair; transcription (genetics);     Show all 19 Subjects
Abstract:
... to limited information regarding the role of sestrin in mercury-induced gastrointestinal adversities, it was hypothesized that modulation of sestrin may improve the mercury-induced gastrointestinal adversities in Drosophila. Here, we fed Drosophila with 400 μM HgCl₂ and found that sestrin transcriptional level was significantly increased in midguts. Sestrin knockdown in HgCl₂-exposed midguts decreased ...
DOI:
10.1016/j.cbpc.2021.109083

16. Guadipyr, a new insecticide, induces microbiota dysbiosis and immune disorders in the midgut of silkworms (Bombyx mori)

Author:
Jiayin Hou; Jianzhong Yu; Zhaohai Qin; Xinju Liu; Xueping Zhao; Xiuqing Hu; Ruixian Yu; Qiang Wang; Jingying Yang; Yan Shi; Liezhong Chen
Source:
Environmental pollution 2021 v.286 pp. 117531
ISSN:
0269-7491
Subject:
midgut,   etc   ; Bombyx mori; Pseudomonas; antimicrobial peptides; chronic toxicity; dysbiosis; ecdysterone; immune system; immunity; microorganisms; mulberries; neonicotinoid insecticides; pollution; risk; steroid hormones;     Show all 15 Subjects
Abstract:
... Guadipyr, which combines neonicotinoid and semicarbazone functional groups in one molecule, exhibits good activity on several pests and high acute and chronic toxicity to silkworms (Bombyx mori). In this report, the effects of low-dose guadipyr on the midgut microbiota and immune system of silkworms were studied. Results showed that the structure and richness of the midgut microbiota of silkworms ...
DOI:
10.1016/j.envpol.2021.117531

17. Gliding motility protein LIMP promotes optimal mosquito midgut traversal and infection by Plasmodium berghei

Author:
Saskia Egarter; Jorge M. Santos; Jessica Kehrer; Julia Sattler; Friedrich Frischknecht; Gunnar R. Mair
Source:
Molecular and biochemical parasitology 2021 v.241 pp. 111347
ISSN:
0166-6851
Subject:
midgut,   etc   ; Culicidae; Plasmodium berghei; blood meal; females; liver; malaria; oocysts; ookinetes; parasitology; ribonucleoproteins; rodents; sporozoites; surface proteins; translation (genetics);     Show all 15 Subjects
Abstract:
... Substrate-dependent gliding motility is key to malaria transmission. It mediates host cell traversal, invasion and infection by Plasmodium and related apicomplexan parasites. The 110 amino acid-long cell surface protein LIMP is essential for P. berghei sporozoites where it is required for the invasion of the mosquito’s salivary glands and the liver cells of the rodent host. Here we define an addit ...
DOI:
10.1016/j.molbiopara.2020.111347

18. Functional characterization and transcriptomic profiling of a spheroid-forming midgut cell line from Helicoverpa zea (Lepidoptera: Noctuidae)

Author:
Elena Vorgia; Mantha Lamprousi; Shane Denecke; Kathrin Vogelsang; Sven Geibel; John Vontas; Vassilis Douris
Source:
Insect biochemistry and molecular biology 2021 v.128 pp. 103510
ISSN:
0965-1748
Subject:
midgut,   etc   ; Helicoverpa zea; cell lines; enterocytes; genetic engineering; genetic vectors; insect biochemistry; insects; landscapes; mammals; molecular biology; pesticides; stress response; transcriptomics; transfection;     Show all 15 Subjects
Abstract:
... Insect cell lines have been frequently used in insect science research in recent years. Establishment of cell lines from specialized tissues like the lepidopteran midgut is expected to facilitate research efforts towards the understanding of uptake and metabolic properties, as well as the design of assays for use in pesticide discovery. However, the number of available lines from specialized ...
DOI:
10.1016/j.ibmb.2020.103510

19. Mitochondrial F1FO-ATPase and permeability transition pore response to sulfide in the midgut gland of Mytilus galloprovincialis

Author:
Cristina Algieri; Salvatore Nesci; Fabiana Trombetti; Micaela Fabbri; Vittoria Ventrella; Alessandra Pagliarani
Source:
Biochimie 2021 v.180 pp. 222-228
ISSN:
0300-9084
Subject:
midgut,   etc   ; Mytilus galloprovincialis; calcium; death; enzyme activity; enzymes; mitochondria; mussels; permeability; sulfides;     Show all 10 Subjects
Abstract:
... of the mitochondrial F₁FO-ATPase in the mPTP is increasingly sustained, the substitution of the natural cofactor Mg²⁺ by Ca²⁺ in the F₁FO-ATPase activation has been involved in the mPTP mechanism. In mussel midgut gland mitochondria the similar kinetic properties of the Mg²⁺- or Ca²⁺-dependent F₁FO-ATPase activities, namely the same affinity for ATP and bi-site activation kinetics by the ATP substrate, in spite ...
DOI:
10.1016/j.biochi.2020.11.012

20. Spiromesifen induces histopathological and cytotoxic changes in the midgut of the honeybee Apis mellifera (Hymenoptera: Apidae)

Author:
Raissa Santana Serra; Jamile Fernanda Silva Cossolin; Matheus Tudor Cândido Santos de Resende; Mayara Arthidoro de Castro; André Henrique Oliveira; Luis Carlos Martínez; José Eduardo Serrão
Source:
Chemosphere 2021 v.270 pp. 129439
ISSN:
0045-6535
Subject:
Apis mellifera; absorption; adverse effects; cytotoxicity; digestion; epithelium; histology; histopathology; ingestion; longevity; mitochondria; mortality; peritrophic membrane; pollinators; rough endoplasmic reticulum; spiromesifen
Abstract:
... The honeybee Apis mellifera is an important pollinator that, similarly to other bees, undergoes colony losses due to several problems, including the use of pesticides in the agriculture. In addition to direct mortality, pesticides cause side-effects in some non-target organs, such as the midgut, which is the main organ for digestion and absorption. Spiromesifen is a pesticide used to control ...
DOI:
10.1016/j.chemosphere.2020.129439