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1. The dlt operon contributes to the resistance to chlorhexidine in Streptococcus mutans

Author:
Shan Huang; Minjing Wu; Yijun Li; Jingyun Du; Shuai Chen; Shan Jiang; Xiaojing Huang; Ling Zhan
Source:
International journal of antimicrobial agents 2022 v.59 no.3 pp. 106540
ISSN:
0924-8579
Subject:
minimum inhibitory concentration,   etc   ; Streptococcus mutans; chlorhexidine; dental caries; hydrophobicity; operon;     Show all 6 Subjects
Abstract:
... Chlorhexidine (CHX) is considered to be the gold standard for dental caries prevention and is widely applied in dental practice. However, the long-term application of CHX may result in CHX-resistance in oral pathogens. The aim of this study was to investigate whether long-term use of CHX causes resistance in Streptococcus mutans and to explore the possible associated mechanisms. Four different S. ...
DOI:
10.1016/j.ijantimicag.2022.106540

2. Pharmacodynamics of ceftriaxone for the treatment of methicillin‐susceptible Staphylococcus aureus: is it a viable treatment option?

Author:
A.J. Heffernan; F.B. Sime; S. Mohd Sazlly Lim; S. Adiraju; S.C. Wallis; J. Lipman; G.D. Grant; J.A. Roberts
Source:
International journal of antimicrobial agents 2022 v.59 no.3 pp. 106537
ISSN:
0924-8579
Subject:
minimum inhibitory concentration,   etc   ; Staphylococcus aureus; bacterial growth; ceftriaxone; inoculum; models; pharmacodynamics;     Show all 7 Subjects
Abstract:
... Ceftriaxone is a broad-spectrum cephalosporin that may be one option to treat methicillin-susceptible Staphylococcus aureus (MSSA). Although MSSA may be susceptible to ceftriaxone, the minimum inhibitory concentration (MIC) is generally two- to four-fold higher than other susceptible bacterial pathogens. This study aimed to explore the pharmacodynamics of ceftriaxone against MSSA and to determine ...
DOI:
10.1016/j.ijantimicag.2022.106537

3. Combined antibacterial and antibiofilm activity of phenyllactic acid and bacteriocin XJS01 against Shigella flexneri

Author:
Yu-Hang Jiang; Lin-Yu Yang; Wei-Gang Xin; Qi-Lin Zhang
Source:
Food bioscience 2022 v.45 pp. 101512
ISSN:
2212-4292
Subject:
minimum inhibitory concentration,   etc   ; Shigella flexneri; antibacterial properties; bacteriocins; biofilm; deformation; phenyllactic acid; plankton;     Show all 8 Subjects
Abstract:
... This study investigated antibacterial and antibiofilm activity of the combined use of phenyllactic acid (PLA) and bacteriocin XJS01 against Shigella flexneri_14. The minimum inhibitory concentration (MIC) of PLA and XJS01 against S. flexneri_14 was 2.45 mg/mL and 18.75 μg/mL, respectively. Growth and kill kinetics assays showed that the combined use of 1/2MIC PLA plus 1/2MIC XJS01 had a better act ...
DOI:
10.1016/j.fbio.2021.101512

4. Nondegradable Antimicrobial Silver-Based Perovskite

Author:
Cyrus Talebpour; Fereshteh Fani; Marc Ouellette; Hossein Salimnia; Houshang Alamdari
Source:
ACS sustainable chemistry & engineering 2022 v.10 no.15 pp. 4922-4928
ISSN:
2168-0485
Subject:
minimum inhibitory concentration,   etc   ; Pseudomonas aeruginosa; Staphylococcus aureus; antimicrobial properties; corrosion; green chemistry; silver;     Show all 7 Subjects
Abstract:
... We synthesized nanostructured AgNbO₃ silver perovskite oxide, which prevents the proliferation of microbial cells without undergoing corrosion. The compound was tested for antimicrobial activity against Gram-positive Staphylococcus aureus and Gram-negative Pseudomonas aeruginosa. We confirmed that the antimicrobial activity of the compound was not related to its high dielectric and piezoelectric p ...
DOI:
10.1021/acssuschemeng.1c08181

5. Development of Quality Control Ranges for Biocide Susceptibility Testing

Author:
Angela R. Schug; Anissa D. Scholtzek; John Turnidge; Marita Meurer; Stefan Schwarz; Andrea T. Feßler; the Biocide Susceptibility Study Group
Source:
Pathogens 2022 v.11 no.2 pp. -
ISSN:
2076-0817
Subject:
minimum inhibitory concentration,   etc   ; benzalkonium chloride; biocides; chlorhexidine; computer software; laboratory experimentation; quality control; solubility;     Show all 8 Subjects
Abstract:
... Every laboratory test needs validation by quality controls. For biocide susceptibility testing (BST), neither quality control (QC) strains nor QC ranges applicable to these strains are currently available. As QC strains, four well-defined laboratory reference strains (Staphylococcus aureus ATCC® 6538, Enterococcus hirae ATCC® 10541, Escherichia coli ATCC® 10536 and Pseudomonas aeruginosa ATCC® 154 ...
DOI:
10.3390/pathogens11020223

6. Streptomyces sp. WR1L1S8 a potent endophytic marine strain for heavy metal resistance and copper removal enhanced by RSM modeling

Author:
Ibtissem Djinni; Warda Djoudi
Source:
Acta ecologica Sinica 2022 v.42 no.2 pp. 80-89
ISSN:
1872-2032
Subject:
minimum inhibitory concentration,   etc   ; Fucus; Streptomyces; agar; atomic absorption spectrometry; endophytes; inoculum; metal tolerance; seawater;     Show all 9 Subjects
Abstract:
... Heavy metal resistance (Cu, Zn, Fe, Cr, Pb, Cd) and removal capacities of 19 selected actinobacteria strains were performed in order to investigate their applicability as bioremediators for polluted areas. Streptomyces sp. WR1L1S8 was used in the present investigation as heavy metals removing strain, which was isolated from inner tissu of the marine brown algae Fucus sp., and identified based on p ...
DOI:
10.1016/j.chnaes.2021.04.004

7. Correlation between Phenotypic and In Silico Detection of Antimicrobial Resistance in Salmonella enterica in Canada Using Staramr

Author:
Amrita Bharat; Aaron Petkau; Brent P. Avery; Jessica C. Chen; Jason P. Folster; Carolee A. Carson; Ashley Kearney; Celine Nadon; Philip Mabon; Jeffrey Thiessen; David C. Alexander; Vanessa Allen; Sameh El Bailey; Sadjia Bekal; Greg J. German; David Haldane; Linda Hoang; Linda Chui; Jessica Minion; George Zahariadis; Gary Van Domselaar; Richard J. Reid-Smith; Michael R. Mulvey
Source:
Microorganisms 2022 v.10 no.2 pp. -
ISSN:
2076-2607
Subject:
minimum inhibitory concentration,   etc   ; Salmonella enterica; antibiotic resistance; computer simulation; epidemiology; gentamicin; humans; phenotype; prediction; Canada;     Show all 10 Subjects
Abstract:
... Whole genome sequencing (WGS) of Salmonella supports both molecular typing and detection of antimicrobial resistance (AMR). Here, we evaluated the correlation between phenotypic antimicrobial susceptibility testing (AST) and in silico prediction of AMR from WGS in Salmonella enterica (n = 1321) isolated from human infections in Canada. Phenotypic AMR results from broth microdilution testing were u ...
DOI:
10.3390/microorganisms10020292

8. Effects of citronellal on growth and enterotoxins production in Staphylococcus aureus ATCC 29213

Author:
Mao Zhang; Hui Li; Addo Keren Agyekumwaa; Yigang Yu; Xinglong Xiao
Source:
Toxicon 2022 v.213 pp. 92-98
ISSN:
0041-0101
Subject:
minimum inhibitory concentration,   etc   ; Staphylococcus aureus; citronellal; dose response; enterotoxins; exotoxins; food industry; hemolysins; hemolysis; pork;     Show all 10 Subjects
Abstract:
... Staphylococcus aureus (S. aureus) is known to be one of the most common foodborne pathogens capable of secreting a wide range of exotoxins such as enterotoxin, which severely threatens the health of consumers. Over the past few years, the development of safe and effective strategies in inhibiting the growth and enterotoxins generation of S. aureus in food turns out to be the research focus and emp ...
DOI:
10.1016/j.toxicon.2022.04.016

9. Lectins ConA and ConM extracted from Canavalia ensiformis (L.) DC and Canavalia rosea (Sw.) DC inhibit planktonic Candida albicans and Candida tropicalis

Author:
Victor Juno Alencar Fonseca; Ana Lays Braga; Ray Silva de Almeida; Taís Gusmão da Silva; Josefa Carolaine Pereira da Silva; Luciene Ferreira de Lima; Maria Helena Cruz dos Santos; Romério Rodrigues dos Santos Silva; Claudener Souza Teixeira; Henrique Douglas Melo Coutinho; Maria Flaviana Bezerra Morais-Braga
Source:
Archives of microbiology 2022 v.204 no.6 pp. 346
ISSN:
0302-8933
Subject:
minimum inhibitory concentration,   etc   ; Canavalia ensiformis; Canavalia rosea; Candida albicans; Candida tropicalis; antifungal properties; fluconazole; plankton;     Show all 8 Subjects
Abstract:
... Lectins participate in the defense against microorganisms and in signaling the damage caused by pathogens to the cell surface and/or intracellular in plants. This study aims to analyze the antifungal potential of lectins extracted from seeds of Canavalia ensiformis (L.) DC and Canavalia rosea (Sw.) DC, against Candida albicans and Candida tropicalis. The antimicrobial tests were performed by micro ...
DOI:
10.1007/s00203-022-02959-x

10. PK/PD modelling of enrofloxacin against Glaesserella parasuis infection in pigs

Author:
Bo Yang; Xiao Dong Li; Xun Chen; Juan Hong; Can Liu; Jin Ping Zheng; Zheng Yang Ou; Dao Jin Yu
Source:
Journal of veterinary pharmacology and therapeutics 2022 v.45 no.3 pp. 291-300
ISSN:
0140-7783
Subject:
minimum inhibitory concentration,   etc   ; antibacterial properties; drug resistance; enrofloxacin; models; mutants; pathogenicity; pharmacodynamics; pharmacokinetics; therapeutics; tryptones;     Show all 11 Subjects
Abstract:
... A pharmacokinetic/pharmacodynamic (PK/PD) model was developed to optimize the dosing regimen of enrofloxacin (EN) against Glaesserella parasuis in pigs. EN (2.5 mg/kg) was administered intramuscularly to eight healthy pigs and eight pigs that were experimentally infected with G. parasuis SW124. Blood samples were collected at predetermined time points. Plasma EN concentrations were determined, and ...
DOI:
10.1111/jvp.13055

11. 2‐Aminoselenazoles and 2‐aminothiazoles: One‐pot synthesis and control of the fungus Colletotrichum lindemuthianum in common beans

Author:
Fernanda AC Pereira; Vitor SC de Andrade; Elaine A Souza; Marcio CS de Mattos; Denilson F Oliveira
Source:
Pest management science 2022 v.78 no.4 pp. 1665-1676
ISSN:
1526-498X
Subject:
minimum inhibitory concentration,   etc   ; Colletotrichum lindemuthianum; anthracnose; azoles; beans; computer simulation; fungi; squalene monooxygenase; synthesis; thiophanate-methyl;     Show all 10 Subjects
Abstract:
... BACKGROUND: Anthracnose, caused by the fungus Colletotrichum lindemuthianum, increases losses in the production of common beans. As 1,3‐diazoles can act against fungi by inhibiting the enzyme squalene epoxidase (SE), 2‐aminoselenazoles and 2‐aminothiazoles were synthesized and subjected to tests with the fungus. In addition, the interactions of the most promising substances with the enzyme SE were ...
DOI:
10.1002/ps.6786

12. Canarimoic acid: new tirucallane triterpene with antisalmonellal activity from the stem bark of Canarium schweinfurthii Engl.

Author:
Jean Baptiste Sokoudjou; Cyrille Ngoufack Tagousop; Afsar Khan; Siméon Pierre Chegaing Fodouop; Serge Secco Atsafack; Norbert Kodjio; Olubunmi Atolani; Donatien Gatsing
Source:
Natural product research 2022 v.36 no.9 pp. 2363-2369
ISSN:
1478-6427
Subject:
minimum inhibitory concentration,   etc   ; Canarium schweinfurthii; Salmonella Enteritidis; Salmonella Typhi; Salmonella Typhimurium; bark; mass spectrometry; research; triterpenoids;     Show all 9 Subjects
Abstract:
... One new tirucallane triterpene named as canarimoic acid (1), and three known analogues: 3β-hydroxytirucalla-8,24-dien-21-oic acid (2), 3α-acetyltirucalla-8,24-diene-21oic acid (3) and 3-oxotirucalla-8,24-dien-21-oic (4) were isolated from the hydro-ethanolic crude extract of Canarium schweinfurthii. Their structures were established by extensive analysis of 1 D and 2 D NMR data in conjunction with ...
DOI:
10.1080/14786419.2020.1836628

13. Antibacterial activity and action mechanism of a novel chitosan oligosaccharide derivative against dominant spoilage bacteria isolated from shrimp Penaeus vannamei

Author:
X.‐Y. Wei; W. Xia; T. Zhou
Source:
Letters in applied microbiology 2022 v.74 no.2 pp. 268-276
ISSN:
0266-8254
Subject:
minimum inhibitory concentration,   etc   ; Aeromonas bestiarum; Litopenaeus vannamei; Shewanella putrefaciens; antibacterial properties; bacterial growth; chitosan; oligosaccharides; shrimp; spoilage;     Show all 10 Subjects
Abstract:
... With the aim of exploring the potential application of a novel chitosan oligosaccharide derivative (COS‐All‐Tio) in shrimp preservation, six dominant spoilage bacteria in the spoiled shrimp (Penaeus vannamei) were isolated and identified as Shewanella putrefaciens (RMS1), S. putrefaciens (S2), Pseudomonas weihenstephanensis (P1), P. gessardii (P2), Aeromonas bestiarum (A1) and Aeromonas molluscoru ...
DOI:
10.1111/lam.13596

14. Antibacterial activity and mechanism of chloroform fraction from aqueous extract of mugwort leaves (Artemisia argyi L.) against Staphylococcus aureus

Author:
J.‐J. Zhang; L.‐B. Qu; Y.‐F. Bi; C.‐X. Pan; R. Yang; H.‐J. Zeng
Source:
Letters in applied microbiology 2022 v.74 no.6 pp. 893-900
ISSN:
0266-8254
Subject:
minimum inhibitory concentration,   etc   ; Artemisia argyi; Artemisia vulgaris; Staphylococcus aureus; antibacterial properties; apoptosis; cell membranes; chloroform; metabolism; permeability;     Show all 10 Subjects
Abstract:
... In this work, the antibacterial activity and mechanism of chloroform fraction obtained from aqueous extract of mugwort leaves against Staphylococcus aureus were investigated. The extract showed obvious antibacterial activity against S. aureus which the minimum inhibitory concentration and minimum bactericidal concentration were determined to be 3·0 and 6·0 mg ml⁻¹ respectively. The mechanism study ...
DOI:
10.1111/lam.13684

15. Antifungal activity and mechanism of d-limonene against foodborne opportunistic pathogen Candida tropicalis

Author:
Hao Yu; Zi-Xi Lin; Wen-Liang Xiang; Ming Huang; Jie Tang; Yue Lu; Qiu-Huan Zhao; Qing Zhang; Yu Rao; Lei Liu
Source:
Lebensmittel-Wissenschaft + Technologie 2022 v.159 pp. 113144
ISSN:
0023-6438
Subject:
minimum inhibitory concentration,   etc   ; Candida tropicalis; antifungal properties; cell membranes; food industry; homeostasis; limonene; opportunistic pathogens; permeability; spoilage;     Show all 10 Subjects
Abstract:
... Limonene can inhibit the common spoilage fungi in food, but few studies elucidated its antifungal activity and mechanism against Candida tropicalis to date. Therefore, this study aimed to the antifungal activity and mechanism of d-limonene against C. tropicalis. The minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) of d-limonene against C. tropicalis were 20 μL/mL a ...
DOI:
10.1016/j.lwt.2022.113144

16. Antimicrobial and antioxidant activities of secondary metabolites from endophytic fungus Botryosphaeria fabicerciana (MGN23-3) associated to Morus nigra L

Author:
Angela Aparecida da Silva; Julio Cesar Polonio; Aline Maria Bulla; Andressa Domingos Polli; Juliana Cristina Castro; Lilian Capelari Soares; Verci Alves de Oliveira-Junior; Veronica Elisa Pimenta Vicentini; Arildo José Braz de Oliveira; José Eduardo Gonçalves; Regina Aparecida Correia Gonçalves; João Lúcio Azevedo; Benício Alves de Abreu-Filho; João Alencar Pamphile
Source:
Natural product research 2022 v.36 no.12 pp. 3158-3162
ISSN:
1478-6427
Subject:
minimum inhibitory concentration,   etc   ; Bacillus cereus; Botryosphaeria; Morus nigra; antioxidant activity; antioxidants; cytotoxicity; endophytes; fungi; research; secondary metabolites;     Show all 11 Subjects
Abstract:
... This study was to evaluate the biological activity of the extract of Botryosphaeria fabicerciana isolated from leaves of Morus nigra. The volatile compounds from the crude extract were analysed by GC-MS which demonstrate that mellein and β-orcinaldehyde were are the major compounds. The best minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of the extract was obse ...
DOI:
10.1080/14786419.2021.1947272

17. Genotyping of methicillin-resistant Staphylococcus aureus isolates causing invasive infections using spa typing and their correlation with antimicrobial susceptibility

Author:
Wei-Yao Wang; Po-Ren Hsueh; Shih-Ming Tsao; TIST Study Group
Source:
International journal of antimicrobial agents 2022 v.59 no.3 pp. 106525
ISSN:
0924-8579
Subject:
minimum inhibitory concentration,   etc   ; agar; antibiotic resistance; daptomycin; genes; genotyping; methicillin-resistant Staphylococcus aureus; monitoring; tigecycline; vancomycin; Taiwan;     Show all 11 Subjects
Abstract:
... Correlation of antimicrobial susceptibility patterns with particular spa types could help physicians select appropriate antibiotics for the treatment of invasive methicillin-resistant Staphylococcus aureus (MRSA) infections. The aim of this study was to investigate invasive MRSA isolates through delineating the molecular typing results and correlating them with antibiotic susceptibility testing re ...
DOI:
10.1016/j.ijantimicag.2022.106525

18. Multifunctional poly(vinyl alcohol) films using cellulose nanocrystals/oregano and cellulose nanocrystals/cinnamon Pickering emulsions: Effect of oil type and concentration

Author:
Ahmed A. Oun; Gye Hwa Shin; Jun Tae Kim
Source:
International journal of biological macromolecules 2022 v.194 pp. 736-745
ISSN:
0141-8130
Subject:
minimum inhibitory concentration,   etc   ; Escherichia coli; antioxidants; cellulose; cinnamon; emulsions; nanocrystals; oils; oregano; oregano oil; stabilizers; zeta potential;     Show all 12 Subjects
Abstract:
... Poly (vinyl alcohol) (PVA) films with high transparency, UV-barrier, antioxidant, and antimicrobial properties were prepared using oregano essential oil (OEO) and cinnamon essential oil (CEO) Pickering emulsions. The effect of Pickering emulsion type and concentration on the PVA film properties was studied. Cellulose nanocrystals (CNCs) were used as a natural stabilizer to prepare OEO and CEO Pick ...
DOI:
10.1016/j.ijbiomac.2021.11.119

19. Pharmacokinetic and pharmacodynamic analysis of cefoperazone/sulbactam for the treatment of pediatric sepsis by Monte Carlo simulation

Author:
Linhu Ye; Lei Cheng; Lingti Kong; Xinqian Zhao; Guoyan Xie; Jing He; Hong Liu; Yan Deng; Xinyu Wu; Tingting Wang; Xixiao Yang
Source:
Analytical methods 2022 v.14 no.11 pp. 1148-1154
ISSN:
1759-9679
Subject:
minimum inhibitory concentration,   etc   ; Monte Carlo method; beta-lactamase; cefoperazone; computer software; pharmacodynamics; pharmacokinetics; probability; sulbactam; therapeutics; toxicity;     Show all 11 Subjects
Abstract:
... Pediatric sepsis syndrome is one of the most common reasons for pediatric intensive care unit hospitalization (PICU). Cefoperazone/sulbactam is a time-dependent beta-lactamase inhibitor combination which has been widely used in the treatment of sepsis. But the pharmacokinetic (PK) and pharmacodynamic (PD) data of cefoperazone/sulbactam are unknown in children with sepsis. The present work aimed to ...
DOI:
10.1039/d1ay01385h

20. Preparation of amphotericin B-loaded hybrid liposomes and the integration of chitin-binding proteins for enhanced antifungal activity

Author:
Pugoh Santoso; Takuya Komada; Yugo Ishimine; Hiromasa Taniguchi; Kosuke Minamihata; Masahiro Goto; Toki Taira; Noriho Kamiya
Source:
Journal of bioscience and bioengineering 2022 pp. -
ISSN:
1389-1723
Subject:
minimum inhibitory concentration,   etc   ; Pteris; Trichoderma viride; amphotericin B; antifungal properties; particle size distribution; solubility; toxicity; zeta potential;     Show all 9 Subjects
Abstract:
... Amphotericin B (AMB) is a gold standard antifungal drug because of its broad-spectrum activity toward pathogenic yeasts and molds. Because of its low solubility in water and toxicity toward humans, several lipid-based formulations that either increase the aqueous solubility or decrease the side effects have been employed in practical use. In our previous research, we found that the combination of ...
DOI:
10.1016/j.jbiosc.2022.06.005