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monoterpenoids, etc ; alkaloids; biosynthesis; indoles; organelles; plant biology; synthetic biology; Show all 7 Subjects
Abstract:
... Plants produce many compounds used by humans as medicines, including alkaloids of the benzylisoquinoline (BIA), monoterpene indole (MIA) and tropane classes. The biosynthetic pathways of these pharmaceutical alkaloids are complex and spatially segregated across several tissues, cell-types and organelles. This review discusses the origin of primary metabolic inputs required by these specialized bio ...
monoterpenoids, etc ; asphyxia; chemotaxonomy; computer software; death; malaria; metabolites; probability; solvents; strychnine; Show all 10 Subjects
Abstract:
... Plants of the Strychnos genus, which include about 200 species, are used for multiple traditional purposes as hunting poison, for example, and have shown interesting pharmacological properties, especially curarizing and tetanizing, but also against malaria. Many monoterpene indole alkaloids have already been isolated and identified. Among them, there is strychnine, a famous alkaloid that can cause ...
monoterpenoids, etc ; Dracocephalum moldavica; chemotaxonomy; ecology; glycosides; lignans; norisoprenoids; phytochemicals; spectral analysis; triterpenoids; Show all 10 Subjects
Abstract:
... A phytochemical investigation of the aerial parts of Dracocephalum moldavica L. (Lamiaceae) led to the isolation and characterization of 30 compounds, including eight lignans (1–8), seven phenols (9–15), five triterpenoids (16–20), four monoterpenoids (21–24), four glycosides (25–28) and two megastigmanes (29 and 30). The structures of these compounds were determined by spectroscopic data analysis ...
monoterpenoids, etc ; Polyporus arcularius; biotransformation; enzymes; p-cymene; regioselectivity; research; white-rot fungi; Show all 8 Subjects
Abstract:
... In a previous study, we identified CYP5035S7 of the white-rot fungus Polyporus arcularius with a broad activity towards monoterpenes such as p-cymene. Therefore, in this study we aimed at further exploring the substrate scope of detoxifying CYP5035S7 towards terpenes and semi-preparatively isolating some of the products via whole-cell biotransformation, in order to obtain information about the enz ...
monoterpenoids, etc ; Araliaceae; biological assessment; circular dichroism spectroscopy; glycosides; hydrolysis; hyperplasia; plant biochemistry; sesquiterpenoids; Show all 9 Subjects
Abstract:
... In the course of our continuing search for biologically active compounds from medicinal sources, we further investigated the aqueous extract of Metapanax delavayi (Franch.) J. Wen & Frodin (Araliaceae) leaves. Five undescribed terpene glycosides, liangwanosides B–F referring to two megastigmane glycosides, one monoterpene glycoside, and two sesquiterpene glycosides, together with seven known compo ...
monoterpenoids, etc ; antioxidants; coumarins; cytotoxicity; diterpenoids; endophytes; meroterpenoids; plant biochemistry; polyketides; quinones; sesquiterpenoids; triterpenoids; Show all 12 Subjects
Abstract:
... Plant endophytes have been considered as novel sources of naturally occurring compounds with various biological activities, including cytotoxic, antimicrobial, anti-inflammatory, anticancer, herbicides, antileishmanial and antioxidant. A variety of specialised products, comprising terpenoids, alkaloids, polyketides, phenolic compounds, coumarins, and quinone derivatives have been reported from var ...
monoterpenoids, etc ; Vicia faba; cultivars; faba beans; flavor; food composition; furans; germination; odors; sesquiterpenoids; Show all 10 Subjects
Abstract:
... The effect of germination on flavor attributes of six Vicia faba L. cultivars (Najeh, Saber, Chourouk, Local, Bachar and Badii) was assessed using HS-SPME/GC-MS technique. Of all aroma compounds identified, 37 were emitted by unsprouted (19) and sprouted (28) seeds. However, 32 active odors were characterized in the flours obtained from unsprouted (18) and sprouted (28) grains. The total identific ...
Maurizio Muzzi; Emiliano Mancini; Emiliano Fratini; Manuela Cervelli; Tecla Gasperi; Paolo Mariottini; Tiziana Persichini; Marco Alberto Bologna; Andrea Di Giulio
monoterpenoids, etc ; Meloidae; cantharidin; hemolymph; males; microscopy; mitochondria; muscles; rough endoplasmic reticulum; spermatophores; toxicity; Show all 11 Subjects
Abstract:
... Members of the family Meloidae are known to produce cantharidin, a highly toxic monoterpene found in their hemolymph and exuded as droplets capable of deterring many predators. As a nuptial gift, males transfer large amounts of cantharidin to females via a spermatophore, which is formed by specific accessory glands containing high concentrations of this terpene. Using light, electron and ion beam ...
monoterpenoids, etc ; Catharanthus roseus; biosynthesis; fluorescence; leaf development; medicinal plants; metabolites; research; seedling growth; serpentine; Show all 10 Subjects
Abstract:
... Bioactive specialized (secondary) metabolites are indispensable for plant development or adjustment to their surrounding environment. In many plants, these specialized metabolites are accumulated in specifically differentiated cells. Catharanthus roseus is a well-known medicinal plant known for producing many kinds of monoterpenoid indole alkaloids (MIAs). C. roseus has two types of specifically d ...
monoterpenoids, etc ; Cryptococcus neoformans; acetates; carvacrol; methicillin-resistant Staphylococcus aureus; pharmaceutical industry; research; spectral analysis; Show all 8 Subjects
Abstract:
... Monoterpene derivatives are of great biological relevance in the pharmaceutical industry. In the present study, pyrrolidine derivative of a carvotacetone, 3-O-benzylcarvotacetone (1), and selected monoterpenes (3-hydroxy-2-isopropyl-5-methyl-p-benzoquinone (3) and cis-piperitol (5)) were prepared to provide (R)-1-(4-(benzyloxy)-5-isopropyl-2-methylcyclohexa-1,3-dien-1-yl)-pyrrolidine (2), 2-isopro ...
... Phytochemical investigation on the aerial parts of Tabernaemontana bufalina Lour. (Apocynaceae) led to the identification of four undescribed monoterpenoid indole alkaloids named taberbufamines A−D, an undescribed natural product, and fourteen known indole alkaloids. The structures of the undescribed alkaloids were established by spectroscopic and computational methods, and their absolute configur ...
... Most of the glycosidic aroma precursors in grape consist of diglycosides such as rutinoside. Yeast glycosidases have been extensively studied but their activity is limited to monoglucosidic precursors. Yet, there is no study about application of glycosidases active on rutinoside in grape. In this study, we screened Bacillus isolates for their glycosidase activities on rutin and grape aroma precurs ...
... A new monoterpenoid glycoside, together with seven known aliphatic acid derivatives, was isolated from the twigs and leaves of Syzygium fluviatile. Their structures were elucidated by means of NMR and HR-ESI-MS data and comparison with the reported values. This is the first example of a monoterpenoid glycoside from Syzygium plants. ...
... Toward the mavacurane and akuammilane monoterpene indole alkaloids, we developed divergent oxidative couplings between the indole nucleus (at N1 or C7) and the C16-malonate of a common tricyclic model related to strictosidine according to a biosynthetic hypothesis postulated by Hesse and Schmid. These oxidative cyclizations led selectively to the formation of the N1–C16 bond of pleiocarpamine or t ...
monoterpenoids, etc ; Citrus; Ptelea trifoliata; butyrates; gas chromatography; horticulture; humans; mass spectrometry; methyl chavicol; odors; sesquiterpenoids; surveys; Show all 12 Subjects
Abstract:
... Many members of the citrus family (Rutaceae) are valued for the aromatic compounds emitted by their flowers. Ptelea species are unusually cold-hardy members of the Rutaceae, but conflicting descriptions of the fragrance of their unisexual flowers may discourage the use of these trees. We analyzed floral volatiles and human response to these chemicals to test the hypothesis that the fragrance of st ...
monoterpenoids, etc ; Bursaphelenchus xylophilus; forest pathogens; forests; fungi; life history; plant pathology; population growth; virulence; North America; Show all 10 Subjects
Abstract:
... We assessed variation and covariation in life history traits of the forest pathogen Bursaphelenchus xylophilus from a native population in North America. We tested for relationships between life history traits and virulence. There was more than two-fold variation among isolates from the same forest in their population growth rates when feeding on commonly co-occurring fungus. Slow-growing isolates ...
... Four minor undescribed terpenoids, including a monoterpenoid (1) and three triterpenoids (3, 6 and 7), together with 26 known terpenoids were isolated from the stems and twigs of Rhododendron Ovatum. Their structures were identified by extensive spectroscopic analyses and electronic circular dichroism (ECD) techniques. Compound 10 showed excellent cytotoxicity against human colon cancer cell (HCT- ...
Sabrina Heiser; Charles D. Amsler; Cecilia J. Brothers; Margaret O. Amsler; Andrew J. Shilling; Lauren Bozarth; Carmen B. Davis; James B. McClintock; Bill J. Baker
monoterpenoids, etc ; Amphipoda; Plocamium; chemical ecology; community structure; diet; macroalgae; predation; reproductive performance; secondary metabolites; Antarctic region; Show all 11 Subjects
Abstract:
... The consequences of defensive secondary metabolite concentrations and interspecific metabolite diversity on grazers have been extensively investigated. Grazers which prefer certain food sources are often found in high abundance on their host and as a result, understanding the interaction between the two is important to understand community structure. The effects of intraspecific diversity, however ...
monoterpenoids, etc ; Vangueria; research; rutin; saponins; Show all 5 Subjects
Abstract:
... Phytochemical investigation of the methanolic extract of Vangueria agrestis aerial parts led to the isolation and characterization of four monoterpene rhamnosides, two ursane saponins, and six flavonoid glycosides. Of these constituents, are three undescribed monoterpene glycosides, vangagrestosides A-C. The reported constituents comprise the monoterpene glycoside [(2E,6Z)−2,6-dimethyl-8-[O-α-L-rh ...
monoterpenoids, etc ; cyclohexanes; indole alkaloids; piperidines; Show all 4 Subjects
Abstract:
... A new monoterpenoid indole alkaloid, arboduridine (1), characterized by a hexacyclic cage skeleton, incorporating cyclohexane, piperidine, and bridged-fused pyrrolidine-tetrahydrofuran moieties, was isolated from a Malayan Kopsia species. The structure of the alkaloid was determined based on analysis of the NMR and MS data, while the absolute configuration was established by ECD measurements in co ...