PubAg

Main content area

You searched for: Subject "naringenin" Remove constraint Subject: "naringenin"
Start Over

Search

1,477  Search Results

« Previous | 1 - 20 of 1,477 |
Number of results to display per page

Search Results

1. Synthesis of Flavanones via Palladium(II)-Catalyzed One-Pot β-Arylation of Chromanones with Arylboronic Acids

Author:
Yoo, Hyung-Seok; Son, Seung Hwan; Cho, Yang Yil; Lee, Soo Jin; Jang, Hyu Jeong; Kim, Young Min; Kim, Dong Hwan; Kim, Nam Yong; Park, Boyoung Y.; Lee, Yong Sup; Kim, Nam-Jung
Source:
Journal of organic chemistry 2019 v.84 no.16 pp. 10012-10023
ISSN:
1520-6904
Subject:
naringenin,   etc   ; acids; arylation; boronic acids; catalytic activity; chemical structure; ketones; organic chemistry; palladium;     Show all 9 Subjects
Abstract:
... A total of 47 flavanones were expediently synthesized via one-pot β-arylation of chromanones, a class of simple ketones possessing chemically unactivated β sites, with arylboronic acids via tandem palladium(II) catalysis. This reaction provides a novel route to various flavanones, including natural products such as naringenin trimethyl ether, in yields up to 92%. ...
DOI:
10.1021/acs.joc.9b01162

2. Effect of temperature, pH, β- and HP-β-cds on the solubility and stability of flavanones: Naringenin and hesperetin

Author:
Lucas-Abellán, C.; Pérez-Abril, M.; Castillo, J.; Serrano, A.; Mercader, M.T.; Fortea, M.I.; Gabaldón, J.A.; Núñez-Delicado, E.
Source:
Lebensmittel-Wissenschaft + [i.e. und] Technologie 2019 v.108 pp. 233-239
ISSN:
0023-6438
Subject:
naringenin,   etc   ; Citrus; cyclodextrins; functional foods; hesperetin; human health; pH; temperature; water solubility;     Show all 9 Subjects
Abstract:
... Naringenin and hesperetin are two of the most abundant flavanones found in citrus with beneficial effects on human health. However, their poor water solubility imposes considerable limitations to their use in functional foods or nutraceuticals development. In order to increase their aqueous solubility and find a new stable system, the effect of different factors as temperature, pH or complexation ...
DOI:
10.1016/j.lwt.2019.03.059

3. Efficient biosynthesis, analysis, solubility and anti-bacterial activities of succinylglycosylated naringenin

Author:
Zhang, S.; Li, D. D.; Zeng, F.; Zhu, Z. H.; Song, P.; Zhao, M.; Duan, J. A.
Source:
Natural product research 2019 v.33 no.12 pp. 1756-1760
ISSN:
1478-6427
Subject:
naringenin,   etc   ; Bacillus amyloliquefaciens; antibacterial properties; biosynthesis; liquid chromatography; mass spectrometry; nuclear magnetic resonance spectroscopy; water solubility;     Show all 8 Subjects
Abstract:
... A novel water-soluble flavonoid with good anti-bacterial activities, naringenin-6″-succl-7-O-glucoside (7-SGN), was synthesised. It was biotransformed from naringenin by Bacillus amyloliquefaciens FJ18 in aqueous miscible organic media, and characterised by LC-MS and NMR analysis. The solubility of 7-SGN in water was approximately 102 times higher than that of naringenin. These results demonstrate ...
DOI:
10.1080/14786419.2018.1431633

4. Influence of naringenin adaptation and shock on resistance of Staphylococcus aureus and Escherichia coli to pulsed electric fields

Author:
Wang, Lang-Hong; Wen, Qing-Hui; Zeng, Xin-An; Han, Zhong; Brennan, Charles S.
Source:
Lebensmittel-Wissenschaft + [i.e. und] Technologie 2019 v.107 pp. 308-317
ISSN:
0023-6438
Subject:
naringenin,   etc   ; Citrus; Escherichia coli; Staphylococcus aureus; cell membranes; pulsed electric fields; unsaturated fatty acids;     Show all 7 Subjects
Abstract:
... This work was aimed to investigate the stress induced by naringenin, one of the natural antibacterial components in citrus plants on the resistance of Staphylococcus aureus ATCC 6538 and Escherichia coli ATCC 25922 cells to pulsed electric fields (PEF). The results revealed that Staphylococcus aureus and Escherichia coli subjected to naringenin shock (2.0 h) did not significantly change their resi ...
DOI:
10.1016/j.lwt.2019.03.029

5. Modulating heterologous pathways and optimizing fermentation conditions for biosynthesis of kaempferol and astragalin from naringenin in Escherichia coli

Author:
Pei, Jianjun; Chen, Anna; Dong, Ping; Shi, Xuejia; Zhao, Linguo; Cao, Fuliang; Tang, Feng
Source:
Journal of industrial microbiology & biotechnology 2019 v.46 no.2 pp. 171-186
ISSN:
1367-5435
Subject:
naringenin,   etc   ; Escherichia coli; Ginkgo biloba; batch fermentation; biochemical pathways; biosynthesis; gene dosage; genes; kaempferol; screening; transferases;     Show all 11 Subjects
Abstract:
... Kaempferol and astragalin are used as standards to assess the quality of Ginkgo biloba extract and Radix astragali, respectively, and possess numerous biological properties. In this study, we constructed a recombinant strain with a highly efficient biosynthetic pathway of kaempferol by screening key enzyme genes, designing a synthetic fusion enzyme and increasing the gene copy number. By optimizin ...
DOI:
10.1007/s10295-018-02134-6

6. Concentrations of phytoestrogens in conventional, organic and free-range retail milk in England

Author:
Nørskov, Natalja P.; Givens, Ian; Purup, Stig; Stergiadis, Sokratis
Source:
Food chemistry 2019 v.295 pp. 1-9
ISSN:
0308-8146
Subject:
naringenin,   etc   ; coumestrol; daidzein; diet; formononetin; genistein; human health; lignans; management systems; matairesinol; milk; pastures; seasonal variation; England;     Show all 14 Subjects
Abstract:
... The effect of dairy management system (conventional, CNV; organic, ORG; free-range, FRG) and month on retail milk phytoestrogen composition was assessed for 12 consecutive months. ORG milk contained more secoisolariciresinol, matairesinol, lariciresinol, sum of plant lignans, daidzein, genistein, formononetin, naringenin, equol, sum of isoflavones and coumestrol, than CNV and FRG milk. This may be ...
DOI:
10.1016/j.foodchem.2019.05.081

7. Temporal biosynthesis of flavone constituents in flax growth stages

Author:
Zuk, Magdalena; Szperlik, Jakub; Hnitecka, Agata; Szopa, Jan
Source:
Plant physiology and biochemistry 2019 v.142 pp. 234-245
ISSN:
0981-9428
Subject:
naringenin-chalcone synthase,   etc   ; Linum usitatissimum; apigenin; biosynthesis; flax; flowering; gene expression; genes; glycosides; lignin; luteolin; plant growth; signal transduction; vegetation;     Show all 14 Subjects
Abstract:
... Previous studies showed that chalcone synthase (chs) silencing in flax (Linum usitatisimum) induces a signal transduction cascade that leads to extensive modification of plant metabolism. Result presented in the current study, performed on field grown flax plants – (across the whole vegetation period) demonstrates that, in addition to its role in tannin and lignin biosynthesis, the chs gene also p ...
DOI:
10.1016/j.plaphy.2019.07.009

8. Food flavonoid ligand structure/estrogen receptor-α affinity relationships – toxicity or food functionality?

Author:
Ye, Hui; Shaw, Ian C.
Source:
Food and chemical toxicology 2019 v.129 pp. 328-336
ISSN:
0278-6915
Subject:
naringenin,   etc   ; Pleurotus ostreatus; binding capacity; chrysin; estrogen receptors; estrogens; foods; genistein; grapefruits; hydrophobic bonding; ligands; pears; plant estrogens; toxicity; toxicology;     Show all 15 Subjects
Abstract:
... In silico molecular modelling is used to study interactions between flavonoid phytoestrogens and estrogen receptor (ER)α. Twenty flavonoids from foods were studied; e.g., genistein from soy, naringenin from grapefruit, phloretin from pears, chrysin from oyster mushrooms. These potential ligands' molecular attributes and their spatial arrangements that favour binding to the ligand binding cleft (LB ...
DOI:
10.1016/j.fct.2019.04.008

9. The Intestinal Fate of Citrus Flavanones and Their Effects on Gastrointestinal Health

Author:
Stevens, Yala; Rymenant, Evelien Van; Grootaert, Charlotte; Camp, John Van; Possemiers, Sam; Masclee, Adrian; Jonkers, Daisy
Source:
Nutrients 2019 v.11 no.7
ISSN:
2072-6643
Subject:
naringenin,   etc   ; Citrus; anti-inflammatory activity; bioavailability; colon; hesperetin; hesperidin; humans; inflammation; intestinal microorganisms; mechanism of action; metabolites; naringin; phenolic compounds;     Show all 14 Subjects
Abstract:
... Citrus flavanones, with hesperidin and naringin as the most abundant representatives, have various beneficial effects, including anti-oxidative and anti-inflammatory activities. Evidence also indicates that they may impact the intestinal microbiome and are metabolized by the microbiota as well, thereby affecting their bioavailability. In this review, we provide an overview on the current evidence ...
DOI:
10.3390/nu11071464

10. Partition and digestive stability of α-tocopherol and resveratrol/naringenin in whey protein isolate emulsions

Author:
Fang, Zheng; Wusigale,; Bao, Huayan; Ni, Yingzhou; Choijilsuren, Narangerel; Liang, Li
Source:
International dairy journal 2019 v.93 pp. 116-123
ISSN:
0958-6946
Subject:
naringenin,   etc   ; alpha-tocopherol; bioactive compounds; droplets; emulsions; encapsulation; functional foods; hydrophobicity; oils; resveratrol; solubility; whey protein isolate;     Show all 12 Subjects
Abstract:
... Co-encapsulation of multiple bioactive components is an emerging field that shows promise as an approach to develop functional foods. Hydrophobic components are generally dissolved in the inner oil phase of protein-stabilised emulsions. Some components may co-adsorb to oil droplet surfaces, due to the ligand-binding properties of proteins. In this study, α-tocopherol and resveratrol/naringenin wer ...
DOI:
10.1016/j.idairyj.2019.01.017

11. Combined cereal and pulse flavonoids show enhanced bioavailability by downregulating phase II metabolism and ABC membrane transporter function in Caco-2 model

Author:
Ravisankar, Shreeya; Agah, Shima; Kim, Hyemee; Talcott, Susanne; Wu, Chaodong; Awika, Joseph
Source:
Food chemistry 2019 v.279 pp. 88-97
ISSN:
0308-8146
Subject:
naringenin,   etc   ; P-glycoproteins; adenosine triphosphate; adenosinetriphosphatase; apigenin; bioactive properties; bioavailability; diet; enzyme inhibition; grains; membrane permeability; metabolism; models; quercetin;     Show all 14 Subjects
Abstract:
... Predominant flavonoids in cereals and pulses are structurally different and may positively interact to enhance bioactivity in combined diet. This work investigated the effects of combined cereal 3-deoxyflavonoids (apigenin, naringenin) and pulse flavonols (quercetin), along with natural extracts, on their bioavailability and underlying mechanisms using Caco-2 monolayer model. Membrane permeability ...
DOI:
10.1016/j.foodchem.2018.12.006
CHORUS:
10.1016/j.foodchem.2018.12.006

12. The influence of natural antioxidants on polycyclic aromatic hydrocarbon formation in charcoal-grilled chicken wings

Author:
Wang, Chong; Xie, Yunting; Wang, Huiyuan; Bai, Yun; Dai, Chen; Li, Chunbao; Xu, Xinglian; Zhou, Guanghong
Source:
Food control 2019 v.98 pp. 34-41
ISSN:
0956-7135
Subject:
naringenin,   etc   ; 2,2-diphenyl-1-picrylhydrazyl; antioxidants; chicken meat; cooking; green tea; human health; polycyclic aromatic hydrocarbons; quinic acid; risk;     Show all 10 Subjects
Abstract:
... Polycyclic aromatic hydrocarbons (PAHs) are discovered in many common foods and showed potential risks to human health and green tea (GT) extracts have been reported to inhibit PAHs generation. In this study, the effects of 8 pure phenolic compounds existing in GT on the formation of PAHs in charcoal-grilled chicken wings (CWs) and their diphenyl-2-picryl-hydrazyl (DPPH) scavenging activities were ...
DOI:
10.1016/j.foodcont.2018.11.012

13. Hesperetin and Hesperidin Improved β-Carotene Incorporation Efficiency, Intestinal Cell Uptake, and Retinoid Concentrations in Tissues

Author:
Nie, Meimei; Zhang, Zhongyuan; Liu, Chunquan; Li, Dajing; Huang, Wuyang; Liu, Chunju; Jiang, Ning
Source:
Journal of agricultural and food chemistry 2019 v.67 no.12 pp. 3363-3371
ISSN:
1520-5118
Subject:
naringenin,   etc   ; Citrus; beta-carotene; bioavailability; hesperetin; hesperidin; human cell lines; in vitro digestion; intestines; mice; micelles; models; naringin; tissues;     Show all 14 Subjects
Abstract:
... Dietary constituents can influence the bioavailability of carotenoids. This study investigated the effect of citrus flavanones on β-carotene (Bc) bioavailability using four experimental models: in vitro digestion procedure, synthetic mixed micelles, Caco-2 cell monolayers, and gavage experiments in mice. The addition of hesperetin (Hes, 25 μM) and hesperidin (Hes-G, 25 μM) standards significantly ...
DOI:
10.1021/acs.jafc.9b00551

14. The dynamic changes of catechins and related genes in tea (Camellia sinensis) flowers

Author:
Sun, Litao; Wang, Yu; Ding, Zhaotang; Liu, Feng
Source:
Acta physiologiae plantarum 2019 v.41 no.2 pp. 30
ISSN:
0137-5881
Subject:
naringenin-chalcone synthase,   etc   ; Camellia sinensis; biosynthesis; catechin; epicatechin; epigallocatechin gallate; flavonols; flowering; phenylalanine ammonia-lyase; tea; transcription factors; unigenes;     Show all 12 Subjects
Abstract:
... As the main components in tea flowers, catechins are accumulated at each stage of tea flowering. However, little information on the accumulation mechanism of catechins during tea flowering is available. Here, we analyzed the accumulation of catechins in tea flowers as well as the expressions of related genes during tea flowering. The results indicated that 99 unigenes and 269 transcription factors ...
DOI:
10.1007/s11738-019-2822-0

15. Bovine beta-casein micelles as delivery systems for hydrophobic flavonoids

Author:
Li, Mo; Fokkink, Remco; Ni, Yuanying; Kleijn, J. Mieke
Source:
Food hydrocolloids 2019 v.96 pp. 653-662
ISSN:
0268-005X
Subject:
naringenin,   etc   ; anti-inflammatory activity; antioxidants; aqueous solutions; beta-casein; bioactive compounds; calorimetry; cattle; computer simulation; encapsulation; fluorescence emission spectroscopy; grapefruits; hydrocolloids; hydrophobicity; light scattering; micelles; pH; titration;     Show all 18 Subjects
Abstract:
... The milk protein β-casein (β-CN) is an intrinsically unstructured amphiphilic protein that self-assembles into micelles. Naringenin is the main hydrophobic flavanone in grapefruit and has several beneficial biological effects: it exhibits, for example, antioxidant, anticancer and anti-inflammatory activity. This paper shows that naringenin can be encapsulated in β-CN micelles. Fluorescence spectro ...
DOI:
10.1016/j.foodhyd.2019.06.005

16. Enhanced cellular cholesterol efflux by naringenin is mediated through inhibiting endoplasmic reticulum stress - ATF6 activity in macrophages

Author:
Xu, Xiaoting; Lei, Tingwen; Li, Wenchao; Ou, Hailong
Source:
Biochimica et biophysica acta 2019 v.1864 no.10 pp. 1472-1482
ISSN:
1388-1981
Subject:
naringenin,   etc   ; aorta; cardiovascular diseases; cholesterol; endoplasmic reticulum; endoplasmic reticulum stress; gene expression; high density lipoprotein; high fat diet; macrophages; mice; phosphatidylinositol 3-kinase; phosphorylation; tunicamycin;     Show all 14 Subjects
Abstract:
... Naringenin improves lipoprotein profile and protects against cardiovascular disease. ATF6 is an endoplasmic reticulum (ER) stress sensor with the same activation processes with sterol regulator SREBPs. Clinical data revealed that ATF6 expression was associated with plasma cholesterol level. Here, we investigated whether naringenin was involved in the regulation of cholesterol efflux and tested the ...
DOI:
10.1016/j.bbalip.2019.06.005

17. Enzyme-assisted biotransformation increases hesperetin content in citrus juice by-products

Author:
Ruviaro, Amanda Roggia; Barbosa, Paula de Paula Menezes; Macedo, Gabriela Alves
Source:
Food research international 2019 v.124 pp. 213-221
ISSN:
0963-9969
Subject:
naringenin,   etc   ; Citrus; antioxidant activity; beta-glucosidase; bioactive compounds; biotransformation; byproducts; citrus fruits; citrus juices; endo-1,4-beta-glucanase; fruits; glycosides; hesperetin; hydrolysis; phenolic compounds; polygalacturonase; sugars; tannase;     Show all 18 Subjects
Abstract:
... Juice extraction from citrus fruits generates large amounts of residues, which account for 50% of the fruit weight. Citrus juice by-products (CJBs) are a rich source of phenolic glycosides. The enzyme-assisted extraction and biotransformation of phenolic compounds from CJBs were investigated. Pectinase, cellulase, tannase and β-glucosidase were used individually or in combination. The effects of e ...
DOI:
10.1016/j.foodres.2018.05.004

18. An integrated approach for harvesting Natal plum (Carissa macrocarpa) for quality and functional compounds related to maturity stages

Author:
Ndou, Aysha; Tinyani, Peter P.; Slabbert, Retha M.; Sultanbawa, Yasmina; Sivakumar, Dharini
Source:
Food chemistry 2019 v.293 pp. 499-510
ISSN:
0308-8146
Subject:
naringenin,   etc   ; Carissa macrocarpa; active ingredients; antioxidant activity; ascorbic acid; color; cyanidin; fructose; fruits; functional foods; glucose; glucosides; harvesting; maturity stage; principal component analysis; quercetin;     Show all 16 Subjects
Abstract:
... This study aims to link morphological and physico-chemical parameters with maturity stages of Natal plum (Carissa macrocarpa), an edible southern African fruit. Harvesting via an integrative holistic approach is recommended for optimal quality and functional compounds. Fruits at dark green (M1), light green (M2), colour break or pink (M3), red (M4), dark red (M5) stages were harvested in 2016 and ...
DOI:
10.1016/j.foodchem.2019.04.102

19. Comparison of high-throughput microextraction techniques, MEPS and μ-SPEed, for the determination of polyphenols in baby food by ultrahigh pressure liquid chromatography

Author:
Casado, Natalia; Perestrelo, Rosa; Silva, Catarina L.; Sierra, Isabel; Câmara, José S.
Source:
Food chemistry 2019 v.292 pp. 14-23
ISSN:
0308-8146
Subject:
naringenin,   etc   ; chemical species; chlorogenic acid; epicatechin; ferulic acid; gallic acid; infant foods; microextraction; myricetin; nutritive value; pH; polyphenols; rutin; solid phase extraction; solvents; sorbents; ultra-performance liquid chromatography;     Show all 17 Subjects
Abstract:
... In this study, two different high-throughput microextraction techniques, microextraction by packed sorbents (MEPS) and micro solid phase extraction (μ-SPEed®), were evaluated and compared, regarding the performance criteria, for the isolation of polyphenols from baby foods prior to their determination by ultrahigh pressure liquid chromatography (UHPLC). To achieve the best performance, influential ...
DOI:
10.1016/j.foodchem.2019.04.038

20. Naringin and Naringenin Relax Rat Tracheal Smooth by Regulating BKCₐ Activation

Author:
Shi, Rui; Xu, Jia-Wen; Xiao, Zi-Ting; Chen, Ruo-Fei; Zhang, Yi-Lin; Lin, Jia-Bi; Cheng, Ke-Ling; Wei, Gu-Yi; Li, Pei-Bo; Zhou, Wen-Liang; Su, Wei-Wei
Source:
Journal of medicinal food 2019 v.22 no.9 pp. 963-970
ISSN:
1557-7600
Subject:
naringenin,   etc   ; Oriental traditional medicine; asthma; calcium; carbachol; confocal microscopy; cough; diet; glibenclamide; image analysis; myocytes; naringin; plasma membrane; potassium channels; potassium chloride; rats; smooth muscle; tetraethylammonium compounds; therapeutics;     Show all 19 Subjects
Abstract:
... Naringin and its aglycone, naringenin, occur naturally in our regular diet and traditional Chinese medicines. This study aimed to detect an effective therapeutic approach for cough variant asthma (CVA) through evaluating the relaxant effect of these two bioactive herbal monomers as antitussive and antiasthmatic on rat tracheal smooth muscle. The relaxant effect was determined by measuring muscular ...
DOI:
10.1089/jmf.2018.4364