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noninsulin-dependentdiabetesmellitus, etc ; clinical trials; exercise; Show all 3 Subjects
Abstract:
... Literature has proved the benefit of exercise on pulmonary functions among the patients with type 2 diabetes mellitus (T2DM). However, objective tools of exercise intensity prescription have been used in previous trials. The trials to explore the effectiveness of subjective tools-based exercise on pulmonary functions among these patients are scarce. The purpose of this study was to explore the fea ...
noninsulin-dependentdiabetesmellitus, etc ; blood; cataract; diabetic retinopathy; pathophysiology; patients; peptides; Show all 7 Subjects
Abstract:
... Peptide phoenixin (PNX), endocan (EDC), and spexin (SPX) are associated with diabetes. Therefore, the purpose of this study was to investigate the levels of PNX, EDC and SPX in the blood and aqueous humor (AH) of patient with type 2 diabetes with and without DRP and cataract. 30 type 2 diabetes patients with cataract (DM + C), 30 DRP patient with cataract (DRP + C), 30 non-diabetic patient with on ...
noninsulin-dependentdiabetesmellitus, etc ; biomarkers; glycosylation; lipid composition; proteomics; risk; ultracentrifugation; Show all 7 Subjects
Abstract:
... Glycosylation of ApoC-III modulates its function in TG metabolism, with some variants being associated with a more atherogenic lipid profile. These associations have been studied in whole plasma but rarely in individual lipoprotein fractions. In this study, we aimed to measure the relative content of ApoC-III glycoforms in each lipoprotein fraction as a potential biomarker for TG metabolism and ca ...
noninsulin-dependentdiabetesmellitus, etc ; environmental factors; genes; lipoproteins; molecular biology; nutrigenomics; obesity; Show all 7 Subjects
Abstract:
... BACKGROUND: Type 2 diabetes mellitus, a rapidly growing epidemic, and its frequently related complications demand global attention. The two factors commonly attributed to the epidemic are genetic factors and environmental factors. Studies indicate that the genetic makeup at an individual level and the environmental aspects influence the occurrence of the disease. However, there is insufficiency in ...
noninsulin-dependentdiabetesmellitus, etc ; algorithms; logit analysis; metabolism; models; nutrition; prediction; risk assessment; Show all 8 Subjects
Abstract:
... We aimed to develop and evaluate a non-invasive deep learning algorithm for screening type 2 diabetes in UK Biobank participants using retinal images. The deep learning model for prediction of type 2 diabetes was trained on retinal images from 50,077 UK Biobank participants and tested on 12,185 participants. We evaluated its performance in terms of predicting traditional risk factors (TRFs) and ge ...
noninsulin-dependentdiabetesmellitus, etc ; blood serum; ferritin; heterozygosity; linkage disequilibrium; metabolism; nutrition; risk; Show all 8 Subjects
Abstract:
... Elevated serum ferritin is associated with incident Type 2 diabetes (T2D), but the interactions between serum ferritin and genetic factors which may improve understanding underlying mechanism in the development of T2D are still unclear. We determined the gene–ferritin interactions on the development of T2D by genome-wide gene–ferritin interaction analyses.A total of 3405 participants from two pros ...
Mamta Singh; Estella S. Hung; Adrienne Cullum; Rachel E. Allen; Peter J. Aggett; Pamela Dyson; Nita G. Forouhi; Darren C. Greenwood; Rachel Pryke; Roy Taylor; Douglas Twenefour; Ruth Waxman; Ian S. Young
noninsulin-dependentdiabetesmellitus, etc ; carbohydrate intake; carbohydrates; diet; public health; risk assessment; England; Show all 7 Subjects
Abstract:
... In May 2021, the Scientific Advisory Committee on Nutrition (SACN) published a risk assessment on lower carbohydrate diets for adults with type 2 diabetes (T2D)⁽¹⁾. The purpose of the report was to review the evidence on ‘low’-carbohydrate diets compared with the current UK government advice on carbohydrate intake for adults with T2D. However, since there is no agreed and widely utilised definitio ...
noninsulin-dependentdiabetesmellitus, etc ; glucose; lipids; membrane potential; metabolism; neurons; neurotoxicity; obesity; toxicology; Show all 9 Subjects
Abstract:
... A significant rise in the incidence of obesity and type 2 diabetes has occurred worldwide in the last two decades. Concurrently, a growing body of evidence suggests a connection between exposure to environmental pollutants, particularly insecticides, and the development of obesity and type 2 diabetes. This review summarizes key evidence of (1) the presence of different types of neuronal receptors ...
noninsulin-dependentdiabetesmellitus, etc ; edema; heart; hyperlipidemia; hypertension; kidneys; models; mortality; stroke; Ethiopia; Show all 10 Subjects
Abstract:
... The burden of diabetes in Ethiopia is exponentially increasing with more than 68% of people with it being undiagnosed and a death rate of 32%. It is a disease impacting patients with negative somatic, psychological, social, and economic consequences. Patients in Ethiopia have very low awareness about chronic complications, which is very worrying. The study aimed to explore the consequences of thei ...
noninsulin-dependentdiabetesmellitus, etc ; body composition; cardiovascular diseases; lifestyle; males; metabolic syndrome; obesity; risk; Show all 8 Subjects
Abstract:
... Metabolic syndrome (MetS) increases the risk of cardiovascular disease, type 2 diabetes mellitus, and cancer. Despite the higher prevalence of MetS in obese adults, little is known about the effectiveness of intensive and group interventions in improving MetS prevalence. This study aimed to investigate the effectiveness of an intensive lifestyle program in reducing the prevalence of MetS in adults ...
noninsulin-dependentdiabetesmellitus, etc ; COVID-19 infection; blood serum; death; health care workers; hypertension; mortality; Show all 7 Subjects
Abstract:
... Vitamin D₃ has many important health benefits. Unfortunately, these benefits are not widely known among health care personnel and the general public. As a result, most of the world’s population has serum 25-hydroxyvitamin D (25(OH)D) concentrations far below optimal values. This narrative review examines the evidence for the major causes of death including cardiovascular disease, hypertension, can ...
noninsulin-dependentdiabetesmellitus, etc ; adulthood; childhood; children; metabolic syndrome; nutrition education; physical activity; systematic review; Show all 8 Subjects
Abstract:
... Dietary habits, that are formed during childhood and consolidated in adulthood, are known to influence the development of future chronic diseases such as metabolic syndrome or type 2 diabetes. The aim of this review was to evaluate the effectiveness of nutritional interventions carried out in recent years focused on improving the quality of the diet of the child population. A systematic search of ...
noninsulin-dependentdiabetesmellitus, etc ; food security; health services; hunger; nutrition; patients; qualitative analysis; South Carolina; Show all 8 Subjects
Abstract:
... The purpose of this qualitative study is to elucidate how food insecurity affects diabetes self-management among adults with type 2 diabetes mellitus (T2DM). Eleven persons with T2DM who screened as food insecure were recruited from a patient pool of a healthcare system in South Carolina. Interview recordings were transcribed, blinded, and imported into NVivo. Participant ages ranged from 36 to 66 ...
noninsulin-dependentdiabetesmellitus, etc ; cardiovascular diseases; fatty liver; intestinal microorganisms; intestinal mucosa; lipid metabolism; obesity; Show all 7 Subjects
Abstract:
... Metabolic diseases continue to afflict most of the U.S. population. Advancements in gut microbiota research have led to the discovery of various functional roles of microorganisms that influence the development of obesity and co-morbidities including type 2 diabetes, non-alcoholic fatty liver disease and cardiovascular disease. Many mechanisms behind these host-microbe interactions stem from proce ...
noninsulin-dependentdiabetesmellitus, etc ; appetite; bioactive properties; food science; glucose; nutrition; pseudocereals; secretin; therapeutics; vegetables; Show all 10 Subjects
Abstract:
... Proteins and peptides are fundamental components of the cereals, pseudocereals, and legumes, giving them numerous health-beneficial properties. Previous studies have demonstrated that these molecules exerted effects on current therapeutic targets related to type 2 diabetes mellitus, such as incretin hormones (responsible for appetite suppression), dipeptidyl peptidase IV (an enzyme involved in the ...
noninsulin-dependentdiabetesmellitus, etc ; adenocarcinoma; diabetic neuropathy; inflammation; lungs; microRNA; non-coding RNA; pain; pathogenesis; Show all 9 Subjects
Abstract:
... Diabetic neuropathy (DN) is a prevalent complication of diabetes mellitus characterized by pain and inflammation. Long non-coding RNAs (lncRNAs) have been associated with DN. This study aimed to investigate transcript levels of Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), microRNA (miR)-1-3p, and C-X-C motif chemokine receptor 4 (CXCR4) in the DN patients and type 2 diabetes me ...
noninsulin-dependentdiabetesmellitus, etc ; apoptosis; divalent metals; glucose; iron overload; pathogenesis; protective effect; vitamin D; Show all 8 Subjects
Abstract:
... Emerging evidence has deemed vitamin D as a potential candidate for the intervention of type 2 diabetes (T2D). Herein, we explored the underlying mechanisms of T2D prevention by vitamin D, concentrating on pancreatic iron deposition reported recently. Zucker diabetic fatty (ZDF) rats were treated by vitamin D, with age-matched Zucker lean rats as control. As expected, vitamin D treatment for ZDF r ...
noninsulin-dependentdiabetesmellitus, etc ; atherosclerosis; disease diagnosis; glycohemoglobin; metabolism; necrosis; neoplasms; nutrition; regression analysis; risk factors; Show all 10 Subjects
Abstract:
... Growth arrest-specific 6 protein (Gas6) has been established to play important roles in various biological processes, but little is currently known on the role of Gas6 signaling in humans. This research explored the association between Gas6 expression and carotid atherosclerosis (AS) in type 2 diabetes mellitus (T2DM). As many as 126 T2DM patients were recruited in this study and classified into t ...
Isabel A. L. Slurink; Nicolette R. den Braver; Femke Rutters; Nina Kupper; Tom Smeets; Petra J. M. Elders; Joline W. J. Beulens; Sabita S. Soedamah-Muthu
noninsulin-dependentdiabetesmellitus, etc ; cheeses; cream; dairy consumption; ice cream; lipid content; males; milk; sodium; yogurt; Show all 10 Subjects
Abstract:
... PURPOSE: Our aim was to investigate prospective associations of consumption of total dairy and dairy types with incident prediabetes in a Dutch population-based study. METHODS: Two enrolment waves of the Hoorn Studies were harmonized, resulting in an analytic sample of 2262 participants without (pre-) diabetes at enrolment (mean age 56 ± 7.3 years; 50% male). Baseline dietary intake was assessed b ...
noninsulin-dependentdiabetesmellitus, etc ; COVID-19 infection; glucose; molecular biology; sodium; sodium glucose cotransporter-2 inhibitors; Show all 6 Subjects
Abstract:
... Numerous studies demonstrate parallels between CVD, type 2 diabetes mellitus (T2DM) and COVID-19 pathology, which accentuate pre-existing complications in patients infected with COVID-19 and potentially exacerbate the infection course. Antidiabetic drugs such as sodium-glucose transporter-2 (SGLT-2) inhibitors have garnered substantial attention recently due to their efficacy in reducing the sever ...