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omega-3fattyacids, etc ; cognition; cognitive disorders; dementia; erythrocytes; homocysteine; nutrition; Show all 7 Subjects
Abstract:
... BACKGROUND: Recent evidence point towards an interaction between omega-3 (n-3) polyunsaturated fatty acids (PUFA) and plasma homocysteine (Hcy). OBJECTIVES: This study tested the hypothesis that effects of red blood cell n-3 PUFA are modified according to baseline plasma Hcy in the large Mulit-domain Alzheimer Prevention Trial (MAPT) throughout the 3-years of treatment with an additional 2 years o ...
omega-3fattyacids, etc ; cartilage; catabolism; homeostasis; inflammation; osteoarthritis; therapeutics; Canada; Show all 8 Subjects
Abstract:
... Osteoarthritis (OA) is a disease which results in degeneration of cartilage within joints and affects approximately 13.6% of adults over 20 years of age in Canada and the United States of America. OA is characterized by a state of low-grade inflammation which leads to a greater state of cellular catabolism disrupting the homeostasis of cartilage synthesis and degradation. Omega-3 polyunsaturated f ...
omega-3fattyacids, etc ; cardiovascular diseases; clinical trials; fatty acid desaturase; risk; Show all 5 Subjects
Abstract:
... The Dietary Guidelines for Americans recommend increasing the intake of omega-3 polyunsaturated fatty acids. The Omega-3 Index (O3I) is one marker used to assess omega-3 status. The O3I national average is 4.3%, which translates into a high risk for developing cardiovascular disease. Research has reported an association between variants in the two desaturase encoding genes, fatty acid desaturase 1 ...
omega-3fattyacids, etc ; C-reactive protein; inflammation; meta-analysis; nutrition; systematic review; Show all 6 Subjects
Abstract:
... Omega-3 polyunsaturated fatty acids (PUFAs) possess anti-inflammatory properties. There is a lack of consensus regarding the effects of omega-3 PUFAs on C-reactive protein (CRP), a marker of systemic inflammation, in cancer patients. Herein, a meta-analysis of randomized controlled trials was conducted to evaluate the effects of omega-3 PUFAs on CRP levels in patients with cancer. PubMed and EMBAS ...
omega-3fattyacids, etc ; Salvia hispanica; bioactive compounds; encapsulation; milk; oils; oxidation; particle size; Show all 8 Subjects
Abstract:
... α‐linolenic acid (ALA) and α‐lipoic acid (LA) are well‐known bioactives with salutary effects and are potential health supplements. However, they are susceptible to oxidation. To enhance the stability of these fatty acids in dietary products/supplements, the present study was conducted to encapsulate chia oil (as the source of ALA), and LA, together in liposomes. The LA inclusion complex with hydr ...
Arista Nienaber; Mumin Ozturk; Robin Dolman; Renee Blaauw; Lizelle L. Zandberg; Simone van Rensburg; Melinda Britz; Frank E. A. Hayford; Frank Brombacher; Du Toit Loots; Cornelius M. Smuts; Suraj P. Parihar; Linda Malan
omega-3fattyacids, etc ; cell structures; diet; inflammation; interleukin-17; lungs; microbial load; tuberculosis; Show all 8 Subjects
Abstract:
... Non-resolving inflammation is characteristic of tuberculosis (TB). Given their inflammation-resolving properties, n-3 long-chain PUFA (n-3 LCPUFA) may support TB treatment. This research aimed to investigate the effects of n-3 LCPUFA on clinical and inflammatory outcomes of Mycobacterium tuberculosis-infected C3HeB/FeJ mice with either normal or low n-3 PUFA status before infection. Using a two-by ...
omega-3fattyacids, etc ; asthma; childhood; immune system; infancy; pathogenesis; pregnancy; risk; risk reduction; Show all 9 Subjects
Abstract:
... Asthma is the most common chronic non-communicable disease in children, the pathogenesis of which involves several factors. The increasing burden of asthma worldwide has emphasized the need to identify the modifiable factors associated with the development of the disease. Recent research has focused on the relationship between dietary factors during the first 1000 days of life (including pregnancy ...
omega-3fattyacids, etc ; apoptosis; diabetes mellitus; folic acid; food chemistry; homocysteine; metabolism; synergism; Show all 8 Subjects
Abstract:
... The present study aimed to investigate whether a combination of folic acid (FA) and n-3 polyunsaturated fatty acids (PUFA) has a better preventive effect on maternal diabetes-induced neural tube defects (NTD) than FA alone. The experiment included five groups of pregnant mice: healthy control (HC), diabetes mellitus control (DMC), diabetes + n-3 PUFA (DMn-3), diabetes + FA (DMFA), and diabetes + F ...
omega-3fattyacids, etc ; asthma; docosahexaenoic acid; eicosapentaenoic acid; fever; inflammation; lung function; nose; Show all 8 Subjects
Abstract:
... Respiratory diseases include a wide range of pathologies with different clinical manifestations, affecting the normal airways and lung function. An increase in the inflammatory response is considered a characteristic hallmark of these diseases, being also a critical factor for their progression. The n-3 polyunsaturated fatty acids (n-3 PUFAs) eicosapentaenoic acid (C20:4n-3, EPA), docosahexaenoic ...
omega-3fattyacids, etc ; biosynthesis; brain; diet; food chemistry; human health; intestines; linoleic acid; liver; Show all 9 Subjects
Abstract:
... To assess whether farmed tilapia can be a beneficial n-3 long-chain polyunsaturated fatty acid (LC-PUFA) source for human health, four diets with linoleic acid (LA) to α-linolenic acid (ALA) ratios at 9, 6, 3, and 1 were prepared to feed juveniles for 10 weeks, and the LC-PUFA biosynthetic characteristics in the liver, intestine, and brain and the muscular quality were analyzed. It was shown that ...
omega-3fattyacids, etc ; flavor; frozen storage; models; mutton; shelf life; spoilage; storage time; variance; Show all 9 Subjects
Abstract:
... Frozen storage can delay mutton meat spoilage to the maximum extent, prolonging its shelf life. In this experiment, mutton refrigerated for 24 h was used as the control group and that stored at −18°C was used as the experimental group to explore the effects of frozen storage for 90 days on FA, AA, and VOC of the mutton. The results showed that FA, AA, and VOC changed significantly during storage. ...
omega-3fattyacids, etc ; biocatalysis; biotechnology; carboxylic ester hydrolases; docosahexaenoic acid; eicosapentaenoic acid; immobilized enzymes; phospholipases; Show all 8 Subjects
Abstract:
... Functional lipids, mainly ω-3 polyunsaturated fatty acids (n-3 PUFAs) such as eicosapentaenoic (EPA; 20:5n-3) and docosahexaenoic (DHA; 22:6n-3), are known to have a variety of health benefits. Lipases and phospholipases are widely used to prepare different forms of structured lipids, since biocatalytic methods can be carried out under mild conditions, preserving the quality of the products. On th ...
omega-3fattyacids, etc ; atherosclerosis; elderly; fish; fish consumption; myocardial infarction; odds ratio; regression analysis; ultrasonics; Show all 9 Subjects
Abstract:
... Fish and omega-3 fatty acid consumption is known to be beneficial for cardiometabolic health. However, the related evidence for individuals with a relatively higher intake of fish or omega-3 unsaturated fatty acids, e.g., Japanese individuals, is scarce. Therefore, this study aimed to examine the association of fish and omega-3 fatty acid intakes with the carotid intima-media thickness (C-IMT) in ...
omega-3fattyacids, etc ; broiler breeders; diet; docosahexaenoic acid; jejunum; linseed; liver; microalgae; spleen; tissue weight; Show all 10 Subjects
Abstract:
... Dietary long chain polyunsaturated n-3 fatty acids (n-3 FA) may be beneficial to broiler breeder (BB) development. Therefore, the effects of feeding sources of docosahexaenoic acid (DHA) and α-linolenic acid (ALA) from hatch through to 22 weeks of age (woa) on growth, organ weight, and jejunal histomorphology were investigated. A total of 588-day-old Ross × Ross 708 BB were reared on one of 3 diet ...
omega-3fattyacids, etc ; antioxidant activity; cholesterol; consumer acceptance; consumer preferences; lipid content; olives; sheep cheese; Show all 8 Subjects
Abstract:
... During a 30-day experimental period, twenty grazing Comisana ewes received a commercial feed (CTRL) or a concentrate containing 28% dried olive leaves (LEAVES) to investigate the effect on yield and quality of a model cheese and on consumer preference. Cheese yield measured at 0- and 60-days of ageing was greater for LEAVES group. Dietary olive leaves increased cheese fat content, which showed low ...
omega-3fattyacids, etc ; arachidonic acid; blood serum; clinical trials; colon; eicosapentaenoic acid; erythrocytes; nutrition; oxidation; prostaglandins; Show all 10 Subjects
Abstract:
... This study evaluated changes in fatty acids from sera, red blood cells, and colonic biopsies from a phase Ib clinical trial of personalized ω-3 fatty acid dosing in 47 healthy volunteers. The trial aimed to reduce colonic prostaglandin E₂ (PGE₂), a pro-inflammatory product of arachidonic acid (AA) oxidation. The personalized doses ranged 2–10 grams/day (54% eicosapentaenoic acid, EPA, 24% other ω- ...
omega-3fattyacids, etc ; adipocytes; body fat; body weight; docosapentaenoic acid; eicosapentaenoic acid; enzymes; glycerol; lipolysis; triacylglycerols; Show all 10 Subjects
Abstract:
... Δ-6 desaturase (D6D) is a key enzyme in the synthesis of long-chain polyunsaturated fatty acids (LC-PUFA). Evidence suggests that reduced D6D activity not only disrupts LC-PUFA production, but also impacts whole body lipid handling and body weight; however, the mechanisms remain largely unexplored. Therefore, we investigated the effect of D6D inhibition on the regulation of lipid accumulation in 3 ...
omega-3fattyacids, etc ; fat intake; food intake; omega-6 fatty acids; phospholipids; risk; vegan diet; Germany; Show all 8 Subjects
Abstract:
... Over the last few years, the vegan diet has become increasingly popular in Germany. It has been proposed that this diet is generally lower in fat, but less is known about the impact on fatty acid (FA) profiles. Therefore, the cross-sectional “Risks and Benefits of a Vegan Diet” (RBVD) study (n = 72) was used to investigate dietary FA intake as well as plasma phospholipid FA in vegans (n = 36) comp ...
omega-3fattyacids, etc ; adults; altitude; antioxidants; hypoxia; inflammation; neopterin; oxidative stress; prostaglandins; urine; Himalayan region; Nepal; Show all 12 Subjects
Abstract:
... High-altitude locations are fascinating for investigating biological and physiological responses in humans. In this work, we studied the high-altitude response in the plasma and urine of six healthy adult trekkers, who participated in a trek in Nepal that covered 300 km in 19 days along a route in the Kanchenjunga Mountain and up to a maximum altitude of 5140 m. Post-trek results showed an unbalan ...
omega-3fattyacids, etc ; Tribonema; biomass; coproducts; dewatering; eicosapentaenoic acid; fish oils; glass; microalgae; microbial contamination; photobioreactors; Show all 11 Subjects
Abstract:
... It has long been explored to use EPA-rich unicellular microalgae as a fish oil alternative for production of the high-value omega-3 fatty acid eicosapentaenoic acid (EPA, 20:5, n-3). However, none of the efforts have ever reached commercial success. This study reported a filamentous yellow-green microalga Tribonema aequale that possesses the ability to grow rapidly and synthesize significant amoun ...