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You searched for: Subject "parasitology" Remove constraint Subject: "parasitology"
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1. Protecting tissue integrity and enteric function: the case for type 2 inflammation and macrophages

Author:
Qihua Ye; Barbara Balestrieri; Nora A. Barrett
Source:
Trends in parasitology 2022 v.38 no.3 pp. 191-192
ISSN:
1471-4922
Subject:
parasitology,   etc   ; inflammation; macrophages;     Show all 3 Subjects
Abstract:
... Type 2 inflammation (T2I) accompanies many inflammatory diseases. In a recent issue of Cell, Ahrends et al. demonstrate that helminth-elicited T2I preserves excitatory neurons and enteric function through the expansion of Arginase-1 (Arg-1)-expressing macrophages, thereby extending our understanding of the protective functions that T2I can orchestrate in inflamed barrier tissue. ...
DOI:
10.1016/j.pt.2021.12.008

2. Approaches to studying the developmental switch of Strongyloides – Moving beyond the dauer hypothesis

Author:
Mark Viney; Robert Morris
Source:
Molecular and biochemical parasitology 2022 v.249 pp. 111477
ISSN:
0166-6851
Subject:
parasitology,   etc   ; Strongyloides; genotype; phenotype;     Show all 4 Subjects
Abstract:
... Strongyloides’ developmental switch between direct, parasitic and indirect, free-living development has intrigued, confused, and fascinated biologists since it was first discovered more than 100 years ago. Proximately, the switch is controlled by environmental conditions that developing larvae are exposed to, but genotypes differ in their sensitivity to these cues. Ultimately, selection will act o ...
DOI:
10.1016/j.molbiopara.2022.111477

3. Snails, microbiomes, and schistosomes: a three-way interaction?

Author:
Winka Le Clec’h; Stephanie Nordmeyer; Timothy J.C. Anderson; Frédéric D. Chevalier
Source:
Trends in parasitology 2022 v.38 no.5 pp. 353-355
ISSN:
1471-4922
Subject:
parasitology,   etc   ; Schistosoma; microbiome; snails;     Show all 4 Subjects
Abstract:
... Aquatic snails, the intermediate hosts of schistosomes, harbor a diverse unexplored microbiome. We speculate that this may play a critical role in host–parasite interactions. We summarize our current knowledge of snail microbiomes and highlight future research priorities. ...
DOI:
10.1016/j.pt.2022.01.012

4. A CRISPR upgrade unlocks Toxoplasma gene function

Author:
Aurelie Dawson; Christopher J. Tonkin
Source:
Trends in parasitology 2022 pp. -
ISSN:
1471-4922
Subject:
parasitology,   etc   ; Toxoplasma; genes; phenotype;     Show all 4 Subjects
Abstract:
... Forward genetic screens are invaluable in describing gene function. CRISPR has reinvigorated phenotypic screens in Toxoplasma – a model apicomplexan parasite. Two recent papers by Smith et al. and Li et al. take the next big leap in performing forward genetic screens in Toxoplasma by combining conditional gene regulation with CRISPR. ...
DOI:
10.1016/j.pt.2022.07.007

5. The Batman and Robin of liver-stage immunity to malaria

Author:
William R. Heath; Lauren E. Holz; Daniel Fernandez-Ruiz
Source:
Trends in parasitology 2022 v.38 no.1 pp. 7-8
ISSN:
1471-4922
Subject:
parasitology,   etc   ; immunity; liver; malaria; memory;     Show all 5 Subjects
Abstract:
... Malaria parasites replicate within the liver shortly after infection. This stage can be controlled by CD8 T cells, but which subsets undertake this function is unclear. Lefebvre et al. now elegantly show that effector memory T (TEM) cells are avid participants, working as a dynamic duo with liver tissue-resident memory T (TRM) cells to combat infection. ...
DOI:
10.1016/j.pt.2021.11.002

6. Rosettes: a shield for Plasmodium falciparum against artemisinins?

Author:
Stephen J. Rogerson
Source:
Trends in parasitology 2022 v.38 no.3 pp. 193-194
ISSN:
1471-4922
Subject:
parasitology,   etc   ; Plasmodium falciparum; erythrocytes; genes;     Show all 4 Subjects
Abstract:
... Relative resistance of Plasmodium falciparum parasites to artesunate (AS) has been ascribed to mutations in the Kelch 13 gene. Lee et al. describe another potential contributor to resistance: the induction of increased rosetting by trophozoite-infected erythrocytes following short exposures to AS. Dissecting this phenomenon may lead to new insights into AS resistance. ...
DOI:
10.1016/j.pt.2021.12.009

7. Physiological roles and metabolism of γ-aminobutyric acid (GABA) in parasitic protozoa

Author:
Rivo Yudhinata Brian Nugraha; Ghulam Jeelani; Tomoyoshi Nozaki
Source:
Trends in parasitology 2022 v.38 no.6 pp. 462-477
ISSN:
1471-4922
Subject:
parasitology,   etc   ; Protozoa; metabolism; neurotransmitters; pathogenesis;     Show all 5 Subjects
Abstract:
... γ-aminobutyric acid (GABA) is a nonstructural amino acid that serves diverse functions in unicellular and multicellular organisms. Besides its widely established role in mammals as an inhibitory neurotransmitter, the diverse biological roles and metabolism of GABA in protozoan parasites have begun to be unveiled. GABA acts as either the intracellular signal or cell-to-cell messenger to mediate a v ...
DOI:
10.1016/j.pt.2022.02.004

8. Improving helminth genome resources in the post-genomic era

Author:
Stephen R. Doyle
Source:
Trends in parasitology 2022 pp. -
ISSN:
1471-4922
Subject:
parasitology,   etc   ; genes; genomics; helminths; transcriptomics;     Show all 5 Subjects
Abstract:
... Rapid advancement in high-throughput sequencing and analytical approaches has seen a steady increase in the generation of genomic resources for helminth parasites. Now, helminth genomes and their annotations are a cornerstone of numerous efforts to compare genetic and transcriptomic variation, from single cells to populations of globally distributed parasites, to genome modifications to understand ...
DOI:
10.1016/j.pt.2022.06.002

9. On the genetics of malaria parasites, a memoir: Part I, rodent malaria parasites and the first genetic crosses

Author:
Richard Carter
Source:
Parasitology international 2022 v.91 pp. 102635
ISSN:
1383-5769
Subject:
parasitology,   etc   ; genetics; malaria; parasites; rodents;     Show all 5 Subjects
Abstract:
... In this abbreviated extract of his memoirs of a life in malaria research, Richard Carter (1945–2021) describes the beginnings of malaria parasite genetics research at Edinburgh university, culminating in the first laboratory genetic cross between two strains of malaria parasites. This manuscript is an abridged excerpt from Richard Carter's first volume of memoirs describing his career in malaria r ...
DOI:
10.1016/j.parint.2022.102635

10. World association for the advancement of veterinary parasitology (WAAVP) guideline for the evaluation of the efficacy of anthelmintics in food-producing and companion animals: general guidelines

Author:
Thomas Geurden; Emily R. Smith; Jozef Vercruysse; Tom Yazwinski; Terry Settje; Martin K. Nielsen
Source:
Veterinary parasitology 2022 v.304 pp. 109698
ISSN:
0304-4017
Subject:
veterinary parasitology,   etc   ; anthelmintics; guidelines; hosts;     Show all 4 Subjects
Abstract:
... The general WAAVP (World Association for the Advancement of Veterinary Parasitology) guideline on anthelmintic efficacy were prepared to assist researchers with the planning, conduct and interpretation of studies to assess the efficacy of anthelmintic drugs in food-producing and companion animals. General principles are outlined herein to assist in the preparation and execution of dosage determina ...
DOI:
10.1016/j.vetpar.2022.109698

11. First Report of Eimeria vilasi and Eimeria beecheyi in the Golden-Mantled Ground Squirrel (Callospermophilus lateralis)

Author:
John A. Hnida
Source:
Comparative parasitology 2022 v.88 no.2 pp. 177-180
ISSN:
1525-2647
Subject:
parasitology,   etc   ; Callospermophilus lateralis; Eimeria; oocysts; Arizona;     Show all 5 Subjects
Abstract:
... Eimeria vilasi and E. beecheyi are reported for the first time from the golden-mantled ground squirrel (Callospermophilus lateralis). Eimeria vilasi was found in 12 of 35 (34%), and E. beecheyi in 2 of 35 (6%), golden-mantled ground squirrels in Arizona. Sporulated oocysts of E. vilasi were ovoidal, 18.1 × 15.8 (15–21 × 13–18) µm, with a length/width ratio of 1.1 (1.0–1.3), and 1–4 polar granules. ...
DOI:
10.1654/COPA-D-21-00009

12. Host–parasite interactions mediated by cross-species microRNAs

Author:
Xing He; Weiqing Pan
Source:
Trends in parasitology 2022 v.38 no.6 pp. 478-488
ISSN:
1471-4922
Subject:
parasitology,   etc   ; human health; microRNA; parasites; pathogenesis;     Show all 5 Subjects
Abstract:
... Parasitic diseases are still the common diseases that seriously threaten human health and life, and a better understanding of host–parasite interactions is the key to effectively controlling and ultimately eradicating these diseases. MicroRNAs (miRNAs) are ubiquitously expressed in almost all eukaryotic parasites and their hosts. These regulatory noncoding RNAs can be released by donor cells and a ...
DOI:
10.1016/j.pt.2022.02.011

13. How can reasonable and repeatable acaricidal tests of natural products against Sarcoptes and Psoroptes mites be carried out?

Author:
Xiaofei Shang; Xiaolou Miao; Jiyu Zhang
Source:
Veterinary parasitology 2022 v.309 pp. 109763
ISSN:
0304-4017
Subject:
veterinary parasitology,   etc   ; Psoroptes; Sarcoptes; psoroptic mange;     Show all 4 Subjects
Abstract:
... Sarcoptic and psoroptic mange threaten the health of both animals and humans worldwide and result in enormous socioeconomic loss. Discovery of new lead compounds is a major goal for controlling this kind of disease. However, the methodological shortcomings of acaricidal tests against Sarcoptes and Psoroptes mites for screening active compounds in vitro troubles colleagues and should be given more ...
DOI:
10.1016/j.vetpar.2022.109763

14. Transfer of parasitology research to patents worldwide

Author:
Jose Antonio Garrido-Cardenas; Alfredo Alcayde; Francisco Manzano-Agugliaro; Concepcion M. Mesa-Valle
Source:
Acta tropica 2022 v.232 pp. 106532
ISSN:
0001-706X
Subject:
parasitology,   etc   ; databases; humans; industry; malaria; people;     Show all 6 Subjects
Abstract:
... Mankind has known about different parasitic diseases since ancient times. There is no doubt that parasites are the infectious agents that have caused the most deaths throughout history. But even today, parasitic diseases affect more than one billion people worldwide. In this paper, the relationship between articles published in the area of parasitology and international patents in this field from ...
DOI:
10.1016/j.actatropica.2022.106532

15. The developmental trajectories of Toxoplasma stem from an elaborate epigenetic rewiring

Author:
Dayana C. Farhat; Mohamed-Ali Hakimi
Source:
Trends in parasitology 2022 v.38 no.1 pp. 37-53
ISSN:
1471-4922
Subject:
parasitology,   etc   ; Toxoplasma gondii; epigenetics; sexual development;     Show all 4 Subjects
Abstract:
... Toxoplasma gondii is considered to be one of the most successful parasitic pathogens. It owes this success to its flexibility in responding to signals emanating from the different environments it encounters during its multihost life cycle. The adaptability of this unicellular organism relies on highly coordinated and evolutionarily optimized developmental abilities that allow it to adopt the forms ...
DOI:
10.1016/j.pt.2021.07.016

16. First report of Lipoptena mazamae Rondani, 1878 (Diptera: Hippoboscidae) from Paraguay

Author:
Thomas S. Goossen Lebrón; Bolívar R. Garcete-Barrett
Source:
Veterinary Parasitology: Regional Studies and Reports 2022 v.27 pp. 100658
ISSN:
2405-9390
Subject:
veterinary parasitology,   etc   ; Lipoptena mazamae; Bolivia; Paraguay;     Show all 4 Subjects
Abstract:
... We report for the first time from Paraguay the louse-fly Lipoptena mazamae Rondani, 1878 (Diptera: Hippoboscidae), based on an individual retrieved from the body of a gray brocket Mazama gouazoubira (Fischer), found dead in the Tatí Yupí Biological Refuge, in Alto Paraná, Eastern Paraguay. Before this finding, in the decade of the 1940's, this species of fly was wrongly recorded from Paraguay, bas ...
DOI:
10.1016/j.vprsr.2021.100658

17. Single-cell transcriptomics reveals hidden information in trypanosomatids

Author:
Bryan E. Abuchery; Jennifer A. Black; Marcelo S. da Silva
Source:
Trends in parasitology 2022 v.38 no.1 pp. 4-6
ISSN:
1471-4922
Subject:
parasitology,   etc   ; Trypanosomatidae; gene expression; parasites; transcriptomics;     Show all 5 Subjects
Abstract:
... Dixenic parasites often encounter environmental extremes during the transition from vector to host. Preadapted transmission stages overcome these challenges to promote parasites' survival and ensure life cycle progression. Recently, Vigneron et al. and Briggs et al. used single-cell transcriptomics to investigate developmental stage specific gene expression patterns during parasite differentiation ...
DOI:
10.1016/j.pt.2021.10.006

18. Hypothetical bromodomain-containing protein 5 is required for the growth of Toxoplasma gondii

Author:
Ying Zhang; Long Cheng; Hongyu Qiu; Tiancong Sun; Ruipeng Deng; Haiyan Gong; Rongsheng Mi; Yan Huang; Chunren Wang; Zhaoguo Chen
Source:
Veterinary parasitology 2022 v.309 pp. 109767
ISSN:
0304-4017
Subject:
veterinary parasitology,   etc   ; Protozoa; Toxoplasma gondii; acetyltransferases; parasites;     Show all 5 Subjects
Abstract:
... Bromodomain (BRD) is a highly conserved structural module domain, found in various proteins, including chromatin-related proteins, nucleus acetyltransferases, and transcription-associated proteins. Toxoplasma gondii, a zoonotic protozoan, encodes at least 12 predicted BRD-containing proteins (BDPs). Here, we investigated the subcellular location and regulatory role of a hypothetical protein BDP th ...
DOI:
10.1016/j.vetpar.2022.109767

19. Metabolic interactions between disease-transmitting vectors and their microbiota

Author:
Xiumei Song; Zhengwei Zhong; Li Gao; Brian L. Weiss; Jingwen Wang
Source:
Trends in parasitology 2022 v.38 no.8 pp. 697-708
ISSN:
1471-4922
Subject:
parasitology,   etc   ; Glossina; humans; microorganisms; nutrition; pathogens; sand;     Show all 7 Subjects
Abstract:
... Disease-transmitting vectors are living organisms that pass infectious agents from one animal/human to another. The epidemiologically important vectors are usually hematophagous arthropods, including mosquitoes, ticks, triatome bugs, sand flies, and tsetse flies. All of them harbor an endogenous microbiota that functionally complements their host’s biology. Different arthropod vectors are ecologic ...
DOI:
10.1016/j.pt.2022.05.002

20. Host–Parasite Relationships in Veterinary Parasitology: Get to Know Your Enemy before Fighting It

Author:
Javier González-Miguel
Source:
Animals 2022 v.12 no.4 pp. -
ISSN:
2076-2615
Subject:
veterinary parasitology,   etc   ; animals; host-parasite relationships; parasitism;     Show all 4 Subjects
Abstract:
... The evolutionary success of parasitism is directly related to the huge number of species that have evolved this way of life [...] ...
DOI:
10.3390/ani12040448