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1. Size characteristics of asbestiform fibers in lung tissue of animals that grazed in areas rich in ophiolitic outcrops in Central Calabria (Southern Italy)

Author:
Maria Rosaria Bruno; Annapaola Cannizzaro; Angelo Olori; Francesca Tombolini; Federica Angelosanto; Francesco Sinopoli; Biagio Maria Bruni; Francesco Casalinuovo; Antonella Campopiano
Source:
Science of the total environment 2023 v.856 pp. 159061
ISSN:
0048-9697
Subject:
phagocytosis,   etc   ; animal age; asbestos; carcinogenicity; durability; environment; humans; lungs; macrophages; principal component analysis; sheep; Italy;     Show all 12 Subjects
Abstract:
... In Calabria (Southern Italy) naturally occurring asbestos (NOA) mainly occurs in the ophiolitic sequences cropping in the Mount Reventino area. The most common type of asbestos detected was the amphibole tremolite; fibrous antigorite and minor chrysotile were also found. The development of asbestos-related diseases depends on, among other things, the morphological characteristics of fibers, length ...
DOI:
10.1016/j.scitotenv.2022.159061

2. The extracellular non-variable region of Dscam promotes bacterial clearance by promoting phagocytosis of hemocytes in Eriocheir sinensis

Author:
Xiaoli Zhang; Xiaona Zhang; Shibo Zong; Guoqing Shen; Yuehong Zhao; Weiwei Li; Qun Wang
Source:
Developmental and comparative immunology 2023 v.138 pp. 104541
ISSN:
0145-305X
Subject:
phagocytosis,   etc   ; Eriocheir sinensis; antibacterial properties; cell adhesion molecules; crabs; exons; fibronectins; hemocytes; immune response; immune system; immunoglobulins; nervous system;     Show all 12 Subjects
Abstract:
... As the most typical example of mRNA variable splicing, Down Syndrome Cell Adhesion Molecule (Dscam) can produce a large number of mRNA isomers. It plays an important role not only in the nervous system, but also in the immune system. In Eriocheir sinensis, the extracellular region of Dscam has three variable domains, which can produce 25, 34 and 18 exons and encode the N-terminal region of immunog ...
DOI:
10.1016/j.dci.2022.104541

3. Study of effects of dietary quercetin (Que) on growth performance and disease resistance mechanism of Litopenaeus vannamei

Author:
Zhifei Chen; Depeng Fan; Luqing Pan; Chen Su; Yanjun Ding; Mingxiang Lu
Source:
Aquaculture 2023 v.563 pp. 738887
ISSN:
0044-8486
Subject:
phagocytosis,   etc   ; Litopenaeus vannamei; White spot syndrome virus; antibacterial properties; antioxidant activity; aquaculture; catalase; crude fat; disease resistance; gene expression; glutathione; glutathione peroxidase; growth performance; hemocytes; immune response; intestinal microorganisms; mortality; quercetin; shrimp; superoxide dismutase;     Show all 20 Subjects
Abstract:
... The purpose of this study was to evaluate effects of dietary quercetin (Que) on growth performance and disease resistance mechanism of Litopenaeus vannamei. Shrimp were randomly divided into 4 groups, with 3 replicants in each group and 70 shrimp in each replicants. The contents of Que. in the four groups were 0, 0.25, 0.5 and 1 g kg⁻¹, respectively. Samples were taken after 56 days, followed by a ...
DOI:
10.1016/j.aquaculture.2022.738887

4. Effects of two fish-derived probiotics on growth performance, innate immune response, intestinal health, and disease resistance of Procambarus clarkii

Author:
Lei Zhu; Yiming Kong; Xulu Chang; Junchang Feng; Xinru Wang; Libo Hou; Xianliang Zhao; Chao Pei; Xianghui Kong
Source:
Aquaculture 2023 v.562 pp. 738765
ISSN:
0044-8486
Subject:
phagocytosis,   etc   ; Bacillus amyloliquefaciens; Lactococcus lactis; Procambarus clarkii; acid phosphatase; alkaline phosphatase; aquaculture; crayfish; disease resistance; enzyme activity; epithelium; gene expression; glutathione peroxidase; growth performance; hemocytes; intestinal microorganisms; intestines; lysozyme; pathogens; probiotics; specific growth rate; weight gain;     Show all 22 Subjects
Abstract:
... Selection of the appropriate strain for particular aquatic animals is necessary for the desirable benefits of probiotics application in aquaculture, however, it is not very clear whether fish-derived probiotics could provide beneficial effects on invertebrates. In the present study, two fish-derived probiotics, Bacillus amyloliquefaciens, and Lactococcus lactis, were administrated as feed additive ...
DOI:
10.1016/j.aquaculture.2022.738765

5. Transcriptome analysis and pattern recognition receptors (PRRs) identification in different tissues of adult Pacific oysters infected with Vibrio parahaemolyticus

Author:
Petcharat Namwong; Shuang Wang; Qing Kong; Haijin Mou; Lei Ma; Prapansak Srisapoome
Source:
Aquaculture 2023 v.562 pp. 738824
ISSN:
0044-8486
Subject:
phagocytosis,   etc   ; Crassostrea gigas; Gram-negative bacteria; Vibrio parahaemolyticus; adults; aquaculture industry; bacterial adhesion; bacterial infections; carbohydrate binding; cytoskeleton; data collection; epithelium; fluorescent antibody technique; food sanitation; galectins; gene expression; gene expression regulation; genes; host-pathogen relationships; macrophages; mannose; oxidative stress; pathogens; peptidoglycans; peroxidase; recombinant proteins; shellfish culture; transcriptomics;     Show all 28 Subjects
Abstract:
... Contamination of V. parahaemolyticus in raw product and culture areas of Crassostrea gigas has been a concern in food hygiene and infectious diseases in the shellfish aquaculture industry for decades. Although numerous researchers have presently objective of decreasing pathogen microorganism contaminated load in raw oysters or genetics improvement for prevention, the in-depth information at the mo ...
DOI:
10.1016/j.aquaculture.2022.738824

6. In cellulo synthesis of dendrimeric sensors for fluorescence-on imaging of bacterial phagocytosis

Author:
Feng Jiang; Yilong Shi; Xiaoxue Zou; Jiahuai Han; Shoufa Han
Source:
Journal of materials chemistry B 2022 v.10 no.25 pp. 4800-4809
ISSN:
2050-7518
Subject:
phagocytosis,   etc   ; fluorescence; macrophages; molecular weight; pH;     Show all 5 Subjects
Abstract:
... Methods for optical tracking of pathogen–host interactions are of biomedical significance. We herein have reported a high molecular weight pH sensor (Den-pH) that is assembled in bacteria and then stably trapped in bacteria irrespective of bacterial membrane potentials. Endowed with acidity-triggered red fluorescence, Den-pH allows signal-on tracking of S. aureus in phagocytosis by macrophages. In ...
DOI:
10.1039/d1tb02012a

7. The role of neutrophils in antibody-driven autoimmune cytopenias

Author:
Vanessa Krémer; Luc de Chaisemartin; Friederike Jönsson
Source:
international journal of biochemistry & cell biology 2022 v.147 pp. 106231
ISSN:
1357-2725
Subject:
phagocytosis,   etc   ; autoantibodies; complement; macrophages; monocytes; neutrophils;     Show all 6 Subjects
Abstract:
... Autoimmune cytopenias are a consequence of autoantibodies that target blood cell lineages and mark them for their accelerated destruction, mostly through phagocytosis by monocytes and macrophages and complement activation. Neutrophils, although equipped with Fc and complement receptors and effector mechanisms that are critical in other autoimmune conditions, remained long overlooked. Recent report ...
DOI:
10.1016/j.biocel.2022.106231

8. Movement and storage of nematocysts across development in the nudibranch Berghia stephanieae (Valdés, 2005)

Author:
Jessica A. Goodheart; Vanessa Barone; Deirdre C. Lyons
Source:
Frontiers in zoology 2022 v.19 no.1 pp. 16
ISSN:
1742-9994
Subject:
phagocytosis,   etc   ; Cnidaria; Miozoa; confocal microscopy; genes; nematocysts;     Show all 6 Subjects
Abstract:
... BACKGROUND: Intracellular sequestration requires specialized cellular and molecular mechanisms allowing a predator to retain and use specific organelles that once belonged to its prey. Little is known about how common cellular mechanisms, like phagocytosis, can be modified to selectively internalize and store foreign structures. One form of defensive sequestration involves animals that sequester s ...
DOI:
10.1186/s12983-022-00460-1

9. Optimizing Studies of Phagocytic Activity by Flowsight Cytometry in Amphibians

Author:
Stefanny Christie Monteiro Titon; Vania Regina Assis; Braz Titon Junior; Gabriela Sarti Kinker; Nicolle Gilda Teixeira de Queiroz Hazarbassanov; Alan Siqueira Lima; Cristina de Oliveira Massoco; Pedro A. Fernandes; Fernando Ribeiro Gomes; Regina P. Markus
Source:
South american journal of herpetology 2022 v.23 no.1 pp. 58-66
ISSN:
1808-9798
Subject:
phagocytosis,   etc   ; assets; blood; cell structures; herpetology; peritoneum; zymosan;     Show all 7 Subjects
Abstract:
... Phagocytosis is a primary and highly conserved mechanism for clearing the extracellular milieu from pathogens and debris. In amphibians, the lack of antibodies for characterizing the different phenotypes of phagocytic cells has impaired the study of the phagocytic process. We used conventional and flowsight cytometry to determine immune cells' phagocytic activity from the blood and peritoneum of t ...
DOI:
10.2994/SAJH-D-20-00006.1

10. Toxicity of curcumin nanoparticles towards alveolar macrophage: Effects of surface charges

Author:
Ching-Yee Loo; Ee Ling Siew; Paul M. Young; Daniela Traini; Wing-Hin Lee
Source:
Food and chemical toxicology 2022 v.163 pp. 112976
ISSN:
0278-6915
Subject:
phagocytosis,   etc   ; curcumin; cytotoxicity; lungs; macrophages; membrane potential; mitochondrial membrane;     Show all 7 Subjects
Abstract:
... Curcumin has been used for chronic lung diseases management due to its diversified molecular actions. However, the potential cytotoxicity which occurs in cells following the exposure to high concentrations of curcumin has been overlooked. This study evaluated the toxic events of curcumin nanoparticles (Cur-NPs) with alterable surface polarity in alveolar macrophages (NR8383). We aimed to establish ...
DOI:
10.1016/j.fct.2022.112976

11. Effect of water-soluble fullerenes on macrophage surface ultrastructure revealed by scanning ion conductance microscopy

Author:
Hefei Ruan; Xuejie Zhang; Jinghe Yuan; Xiaohong Fang
Source:
RSC advances 2022 v.12 no.34 pp. 22197-22201
ISSN:
2046-2069
Subject:
phagocytosis,   etc   ; drugs; fullerene; macrophages; microscopy; photochemotherapy; ultrastructure; water solubility;     Show all 8 Subjects
Abstract:
... C₆₀-fullerenes have unique potential in antiviral, drug delivery, photodynamic therapy and other biomedical applications. However, little is known about their effects on macrophage surface morphology and ultrastructure. Here by using contact-free scanning ion conductance microscopy (SICM), we investigated the effects of two water-soluble fullerenes on the surface ultrastructure and function of mac ...
DOI:
10.1039/d2ra02403a

12. Housebreaking Plasmodium parasites leave their fingerprints at the door

Author:
Lara Bardtke; Ian A. Cockburn
Source:
Trends in parasitology 2022 pp. -
ISSN:
1471-4922
Subject:
phagocytosis,   etc   ; Plasmodium falciparum; erythrocytes; malaria; merozoites; parasitology; vaccine development;     Show all 7 Subjects
Abstract:
... Protective antibodies against Plasmodium falciparum merozoite antigens, including EBA-175, can inhibit erythrocyte invasion. New data from Musasia et al. indicate that these antibodies can also trigger antibody-dependent phagocytosis of ring-infected and uninfected erythrocytes and that this correlates with protection from malaria. This provides a new pathway for vaccine design. ...
DOI:
10.1016/j.pt.2022.09.005

13. Methodologies and tools to shed light on erythrophagocytosis

Author:
Chloé Turpin; Olivier Meilhac; Emmanuel Bourdon; François Canonne-Hergaux; Philippe Rondeau
Source:
Biochimie 2022 pp. -
ISSN:
0300-9084
Subject:
phagocytosis,   etc   ; atherosclerosis; death; diabetes; disease progression; hemolytic anemia; humans; longevity;     Show all 8 Subjects
Abstract:
... Red blood cells (RBC) are the most abundant circulating cell of the human body. RBC are constantly exposed to multiple stresses in the circulation, leading to molecular and structural impairments and death. The physiological process of RBC senescence or ageing is referred to as eryptosis. At the end of their lifespan, aged RBC are recognized and removed from the blood by professional phagocytes vi ...
DOI:
10.1016/j.biochi.2022.07.017

14. Purification, structural characterization and immunomodulatory activities of a polysaccharide from the fruiting body of Morchella sextelata

Author:
Meng-Ting Kuang; Jing-Yue Xu; Jin-Yu Li; Liu Yang; Bo Hou; Qi Zhao; Jiang-Miao Hu
Source:
International journal of biological macromolecules 2022 v.213 pp. 394-403
ISSN:
0141-8130
Subject:
phagocytosis,   etc   ; Morchella; glucose; interleukin-6; mannose; methylation; molecular weight; polysaccharides;     Show all 8 Subjects
Abstract:
... A novel polysaccharide (MSP-1) was isolated from the fruiting body of Morchella sextelata and purified using DEAE-52 and Sephadex G-75. The molecular weight of MSP-1 was 1.17 × 10⁴ Da, as detected by HPLC analysis. The monosaccharide composition of MSP-1 was mannose and glucose at a ratio of 1.00: 1.25. Methylation and NMR results revealed that the backbone of MSP-1 was composed of →4)-β-D-Manp-(1 ...
DOI:
10.1016/j.ijbiomac.2022.05.096

15. Comparative Analysis Of Selected Immune Parameters in Blood of the Majaheem and Magateer Dromedary Camel Breeds

Author:
Jamal Hussen; Ahmed I. El Sheikh; Faisal Almathen
Source:
Journal of camel practice and research 2022 v.29 no.2 pp. 147-153
ISSN:
2277-8934
Subject:
phagocytosis,   etc   ; Camelus dromedarius; camels; eosinophils; flow cytometry; monocytes; neutrophils; research;     Show all 8 Subjects
Abstract:
... The present study investigated the composition of blood leukocytes in the Magateer and Majaheem camel breeds using immune cell labeling and flow cytometry. In addition, the phagocytosis activity of blood neutrophils and monocytes were compared between the two breeds. Although the total number of leukocytes did not differ significantly between the two camel breeds, a significantly higher fraction a ...
DOI:
10.5958/2277-8934.2022.00020.0

16. The Microglial membrane receptor TREM2 mediates exosome secretion to promote phagocytosis of amyloid‐β by microglia

Author:
Si Huang; Xiaoli Liao; Junyong Wu; Xiaojie Zhang; Yamin Li; Daxiong Xiang; Shilin Luo
Source:
FEBS letters 2022 v.596 no.8 pp. 1059-1071
ISSN:
0014-5793
Subject:
phagocytosis,   etc   ; Alzheimer disease; antigen presentation; central nervous system; exosomes; neuroglia; secretion;     Show all 7 Subjects
Abstract:
... Considerable evidence links the microglial transmembrane receptor TREM2 to the progression of Alzheimer's disease through its involvement in Aβ phagocytosis by microglia. While previous studies have mainly focused on the phagocytic regulation of microglia itself, the antigen presentation of microglial exosomes in the process of immunity has been less investigated. Here, we identified TREM2 express ...
DOI:
10.1002/1873-3468.14336

17. miR-185-5p Regulates Inflammation and Phagocytosis through CDC42/JNK Pathway in Macrophages

Author:
Xirui Ma; Huifang Liu; Jing Zhu; Caoxu Zhang; Yajie Peng; Ziming Mao; Yu Jing; Fengling Chen
Source:
Genes 2022 v.13 no.3 pp. -
ISSN:
2073-4425
Subject:
phagocytosis,   etc   ; cytokines; data collection; inflammation; macrophage activation; macrophages; microRNA; protein synthesis;     Show all 8 Subjects
Abstract:
... Macrophage activation is an essential component of systemic chronic inflammation and chronic inflammatory diseases. Emerging evidence implicates miR-185-5p in chronic inflammation diseases. However, the regulatory role of miR-185-5p in macrophage pro-inflammatory activation has not been studied previously. Here, we identified that miR-185-5p was one of the top genes and effectively downregulated i ...
DOI:
10.3390/genes13030468

18. Measuring the pH of Acidic Vesicles in Live Cells with an Optimized Fluorescence Lifetime Imaging Probe

Author:
Kinuko Koda; Sascha Keller; Ryosuke Kojima; Mako Kamiya; Yasuteru Urano
Source:
Analytical chemistry 2022 v.94 no.32 pp. 11264-11271
ISSN:
1520-6882
Subject:
phagocytosis,   etc   ; acidification; analytical chemistry; endosomes; fluorescence; fluorescent dyes; lysosomes; pH; phagosomes;     Show all 9 Subjects
Abstract:
... Acidification of intracellular vesicles, such as endosomes and lysosomes, is a key pathway for regulating the function of internal proteins. Most conventional methods of measuring pH are not satisfactory for quantifying the pH inside these vesicles. Here, we investigated the molecular requirements for a fluorescence probe to measure the intravesicular acidic pH in living cells by means of fluoresc ...
DOI:
10.1021/acs.analchem.2c01840

19. Biofunctional Attributes of Surface Layer Protein and Cell-Bound Exopolysaccharide from Probiotic Limosilactobacillus fermentum (MTCC 5898)

Author:
Shalaka Bhawal; Ankita Kumari; Suman Kapila; Rajeev Kapila
Source:
Probiotics and antimicrobial proteins 2022 v.14 no.2 pp. 360-371
ISSN:
1867-1306
Subject:
phagocytosis,   etc   ; bacterial adhesion; exopolysaccharides; extracellular matrix; hydrophobicity; macrophages; mice; mucins; probiotics; splenocytes;     Show all 10 Subjects
Abstract:
... The probiotic extracellular matrix components (ECM) have been considered as an important factor in eliciting the beneficial roles of the bacteria. The study involved the growth phase–dependent extraction of the surface layer protein (SLP) and cell-bound exopolysaccharide (EPS-b) from novel Limosilactobacillus fermentum (MTCC 5898). Both SLP and EPS-b were optimally extracted at the late logarithmi ...
DOI:
10.1007/s12602-021-09891-4

20. The role of ficolin as a pattern recognition receptor in antibacterial immunity in Eriocheir sinensis

Author:
Ke Zhao; Yukai Qin; Xingyu Nan; Kaimin Zhou; Yu Song; Weiwei Li; Qun Wang
Source:
Fish & shellfish immunology 2022 v.128 pp. 494-504
ISSN:
1050-4648
Subject:
phagocytosis,   etc   ; Eriocheir sinensis; antibacterial properties; crabs; fish; hemocytes; immune response; lectins; shellfish;     Show all 9 Subjects
Abstract:
... Ficolin, a member of the fibrinogen-related proteins family (FREPs), functions as a pattern recognition receptor (PRR) in vertebrates and in invertebrates as a novel lectin. In this study, we discovered the Ficolin homolog of Chinese mitten crab (Eriocheir sinensis), which we named EsFicolin. The obtained sequence showed that it has a highly conserved C-terminal fibrinogen-related domain (FReD) an ...
DOI:
10.1016/j.fsi.2022.08.047