U.S. flag

An official website of the United States government

PubAg

Main content area

You searched for: Subject "phagocytosis" Remove constraint Subject: "phagocytosis"
Start Over

Search

4,157  Search Results

« Previous | 1 - 20 of 4,157 |
Number of results to display per page

Search Results

1. Virulence Determinants of Colistin-Resistant K. pneumoniae High-Risk Clones

Author:
Dogan, Ozlem; Vatansever, Cansel; Atac, Nazli; Albayrak, Ozgur; Karahuseyinoglu, Sercin; Sahin, Ozgun Ekin; Kilicoglu, Bilge Kaan; Demiray, Atalay; Ergonul, Onder; Gönen, Mehmet; Can, Fusun
Source:
Biology 2021 v.10 no.5
ISSN:
2079-7737
Subject:
phagocytosis,   etc   ; biosynthesis; mortality; neutrophils; operon; virulence;     Show all 6 Subjects
Abstract:
... We proposed the hypothesis that high-risk clones of colistin-resistant K. pneumoniae (ColR-Kp) possesses a high number of virulence factors and has enhanced survival capacity against the neutrophil activity. We studied virulence genes of ColR-Kp isolates and neutrophil response in 142 patients with invasive ColR-Kp infections. The ST101 and ST395 ColR-Kp infections had higher 30-day mortality (58% ...
DOI:
10.3390/biology10050436

2. Complement Proteins as Soluble Pattern Recognition Receptors for Pathogenic Viruses

Author:
Murugaiah, Valarmathy; Varghese, Praveen M.; Beirag, Nazar; De Cordova, Syreeta; Sim, Robert B.; Kishore, Uday
Source:
Viruses 2021 v.13 no.5
ISSN:
1999-4915
Subject:
phagocytosis,   etc   ; chemotaxis; complement; lectins; pathogenesis; virion;     Show all 6 Subjects
Abstract:
... The complement system represents a crucial part of innate immunity. It contains a diverse range of soluble activators, membrane-bound receptors, and regulators. Its principal function is to eliminate pathogens via activation of three distinct pathways: classical, alternative, and lectin. In the case of viruses, the complement activation results in effector functions such as virion opsonisation by ...
DOI:
10.3390/v13050824

3. Age-related dysfunction of p53-regulated phagocytic activity in macrophages

Author:
Yamaguchi, Yohko; Kaida, Kohei; Suenaga, Yusuke; Ishigami, Akihito; Kobayashi, Yoshiro; Nagata, Kisaburo
Source:
Biochemical and biophysical research communications 2020 v.529 no.2 pp. 462-466
ISSN:
0006-291X
Subject:
phagocytosis,   etc   ; macrophages; research;     Show all 3 Subjects
Abstract:
... Aging promotes polarization of M2-like macrophages to M1-like macrophages and reduces their phagocytic ability. However, the molecular mechanisms underlying these aging-related changes remain poorly understood. Here, we demonstrate that p53 regulates phagocytic activity in macrophages from young mice but not in those from old ones. Macrophages from both old and young mice expressed functional p53 ...
DOI:
10.1016/j.bbrc.2020.05.121

4. Phagocytosis in a Shape-shifting Bacterium

Author:
Gallot-Lavallée, Lucie; Archibald, John M.
Source:
Trends in microbiology 2020 v.28 no.6 pp. 428-430
ISSN:
0966-842X
Subject:
phagocytosis,   etc   ; bacteria; eukaryotic cells;     Show all 3 Subjects
Abstract:
... Phagocytosis – cell ingestion – is an important process confined to eukaryotes. Or is it? Shiratori et al. have discovered the existence of phagocytosis in a planctomycete bacterium, raising new questions about the significance of phagotrophy beyond the realm of eukaryotic life. ...
DOI:
10.1016/j.tim.2020.02.017

5. Bacteria compete with hematite nanoparticles during their uptake by the ciliate Tetrahymena thermophila

Author:
Guo, Wen-Bo; Yang, Liu-Yan; Miao, Ai-Jun
Source:
Journal of hazardous materials 2021 v.411 pp. 125098
ISSN:
0304-3894
Subject:
phagocytosis,   etc   ; Tetrahymena thermophila; adsorption; food chain; hematite; ingestion;     Show all 6 Subjects
Abstract:
... Bacterial accumulation of engineered nanoparticles (NPs) result in their transfer along the food chain. However, there are a lot of NPs not associated with bacteria. Whether bacteria, as representative biotic particles, influence the biological uptake of these non-associated NPs in aquatic ecosystems is unclear. In the present study, we examined the effects of four bacterial species on the uptake ...
DOI:
10.1016/j.jhazmat.2021.125098

6. Structural characteristics and immunopotentiation activity of two polysaccharides from the petal of Crocus sativus

Author:
He, Yanfei; Peng, Haoxuan; Zhang, Huifang; Liu, Yaqin; Sun, Hongxiang
Source:
International journal of biological macromolecules 2021 v.180 pp. 129-142
ISSN:
0141-8130
Subject:
phagocytosis,   etc   ; Crocus sativus; chemokines; colorimetry; gene expression; methylation; polysaccharides; solvolysis;     Show all 8 Subjects
Abstract:
... The current experiments were designed to explore the structural features and immunopotentiation activity of two homogeneous polysaccharides PCSPA and PCSPB prepared from Crocus sativus petals using DEAE-Sephadex A-50 and Sephadex G200 column chromatography. The structures of PCSPA and PCSPB were systematically characterized using extensive chemical and spectroscopic methods including colorimetry, ...
DOI:
10.1016/j.ijbiomac.2021.03.006

7. Evaluation of natural endosymbiosis for progress towards artificial endosymbiosis

Author:
Puri, Kartik Mayank; Butardo, Vito, Jr; Sumer, Huseyin
Source:
Symbiosis 2021 v.84 no.1 pp. 1-17
ISSN:
0334-5114
Subject:
phagocytosis,   etc   ; biosynthesis; cytoplasm; endosymbionts; mammals; symbiosis; synthetic biology;     Show all 7 Subjects
Abstract:
... Endosymbiosis or symbiogenesis is a process where a cell hosts another cell that is acquired through phagocytosis or natural entry of the cell within its cytoplasm. Endosymbiosis has a profound effect on the survival of the host cell by conferring nutritional and/or biosynthetic advantage. Therefore, attempts of artificial endosymbiosis have become one of the most challenging projects in synthetic ...
DOI:
10.1007/s13199-020-00741-5

8. Flow Cytometric Assessment of the Viability and Functionality of Uterine Polymorphonuclear Leukocytes in Postpartum Dairy Cows

Author:
Lietaer, Leen; Demeyere, Kristel; Heirbaut, Stijn; Meyer, Evelyne; Opsomer, Geert; Bogado Pascottini, Osvaldo
Source:
Animals 2021 v.11 no.4
ISSN:
2076-2615
Subject:
phagocytosis,   etc   ; Holstein; apoptosis; endometrium; flow cytometry; fluorescence; milk; proteolysis; viability;     Show all 9 Subjects
Abstract:
... Postpartum dairy cows experience impaired peripheral polymorphonuclear leukocyte (PMN) functionality, which has been associated with reproductive tract inflammatory diseases. However, it has not been elucidated yet whether endometrial PMN functionality is (equally) impaired. We developed a method for endometrial PMN isolation and flow cytometric assessment of their viability and functionality. We ...
DOI:
10.3390/ani11041081

9. Bifidobacteria from human origin: interaction with phagocytic cells

Author:
Assad, S.E.; Rolny, I.S.; Minnaard, J.; Pérez, P.F.
Source:
Journal of applied microbiology 2021 v.130 no.4 pp. 1357-1367
ISSN:
1364-5072
Subject:
phagocytosis,   etc   ; humans; immune response; lysosomes; macrophages; probiotics; transferrin;     Show all 7 Subjects
Abstract:
... AIM OF THE STUDY: Given that phagocytic cells are main players of the host immune response, we studied the interaction of bifidobacteria with monocytic THP‐1 cells in nonopsonic conditions. METHODS AND RESULTS: Association/internalization, cell response (expression of HLA‐DR and TLR2), M1/M2 macrophage polarization and colocalization of micro‐organisms with Lysotracker or transferrin were evaluate ...
DOI:
10.1111/jam.14861

10. Lacticaseibacillus paracasei PS23 Effectively Modulates Gut Microbiota Composition and Improves Gastrointestinal Function in Aged SAMP8 Mice

Author:
Chen, Li-Han; Wang, Ming-Fu; Chang, Chun-Chao; Huang, Shih-Yi; Pan, Chun-Hsu; Yeh, Yao-Tsung; Huang, Cheng-Hsieh; Chan, Ching-Hung; Huang, Hui-Yu
Source:
Nutrients 2021 v.13 no.4
ISSN:
2072-6643
Subject:
phagocytosis,   etc   ; Erysipelotrichaceae; Lactobacillus; immunoglobulins; intestinal microorganisms; intestines; mice; permeability; probiotics;     Show all 9 Subjects
Abstract:
... Probiotics are reported to improve gastrointestinal (GI) function via regulating gut microbiota (GM). However, exactly how probiotics influence GM and GI function in elders is poorly characterized. Therefore, in this study, we assessed the effect of the probiotic Lacticaseibacillus paracasei PS23 (LPPS23) on the GM and GI function of aged mice. There were four groups of senescence-accelerated mous ...
DOI:
10.3390/nu13041116

11. A guide to measuring phagosomal dynamics

Author:
Levin‐Konigsberg, Roni; Mantegazza, Adriana R.
Source:
TheFEBS journal 2021 v.288 no.5 pp. 1412-1433
ISSN:
1742-464X
Subject:
phagocytosis,   etc   ; antigen presentation; autophagy; homeostasis; inflammation; metabolites; monitoring; phagosomes; photoluminescence;     Show all 9 Subjects
Abstract:
... Phagocytosis is an essential mechanism for immunity and homeostasis, performed by a subset of cells known as phagocytes. Upon target engulfment, de novo formation of specialized compartments termed phagosomes takes place. Phagosomes then undergo a series of fusion and fission events as they interact with the endolysosomal system and other organelles, in a dynamic process known as phagosome maturat ...
DOI:
10.1111/febs.15506

12. Detachment of RAW264.7 macrophages from a culture dish using ultrasound excited by a Langevin transducer

Author:
Kuriyama, Takuma; Fukuma, Yuki; Imashiro, Chikahiro; Kabayama, Kazuya; Kurashina, Yuta; Takemura, Kenjiro
Source:
Journal of bioscience and bioengineering 2021 v.131 no.3 pp. 320-325
ISSN:
1389-1723
Subject:
phagocytosis,   etc   ; cell viability; culture dishes; macrophages; metabolism; ultrasonics; vibration;     Show all 7 Subjects
Abstract:
... To study the relationship between macrophages and antigens, an efficient culture method for macrophages is important. During culture, macrophages adhering to the culture surface are difficult to harvest by general trypsinization. Thus, prolonged trypsinization or cell scraping has been used to detach macrophages. However, prolonged trypsinization has a negative effect on cell viability, and the de ...
DOI:
10.1016/j.jbiosc.2020.11.003

13. Mechanisms of Rhinovirus Neutralisation by Antibodies

Author:
Touabi, Lila; Aflatouni, Faryal; McLean, Gary R.
Source:
Viruses 2021 v.13 no.3
ISSN:
1999-4915
Subject:
phagocytosis,   etc   ; Enterovirus; antibodies; antibody detection; capsid; neutralization; vaccine development; virion;     Show all 8 Subjects
Abstract:
... Antibodies are a critical immune correlate of protection for rhinoviruses, particularly those antibodies found in the secretory compartment. For nonenveloped viruses such as rhinoviruses, antibody binding to regions of the icosahedral capsid can neutralise infections by a number of different mechanisms. The purpose of this review is to address the neutralising mechanisms of antibodies to rhinoviru ...
DOI:
10.3390/v13030360

14. In Vivo Evaluation of Immune-Enhancing Activity of Red Gamju Fermented by Probiotic Levilactobacillus brevis KU15154 in Mice

Author:
Park, Eunju; Kim, Kee-Tae; Choi, Mijoo; Lee, Yunjung; Paik, Hyun-Dong
Source:
Foods 2021 v.10 no.2
ISSN:
2304-8158
Subject:
phagocytosis,   etc   ; T-lymphocytes; beverages; cytokines; fermentation; immunoglobulins; kimchi; macrophages; probiotics;     Show all 9 Subjects
Abstract:
... The purpose of this study was to evaluate the immune-enhancing effect of red gamju fermented with Levilactobacillus brevis KU15154, isolated from kimchi, as a biofunctional beverage using mice. Thirty-two mice were used, and after a 2-week feeding, the growth, cytokine and immunoglobulin production, and immune-related cell activation (phagocytes and natural killer [NK] cells) of the mice were eval ...
DOI:
10.3390/foods10020253

15. Opsonization but not pretreatment of equine macrophages with hyperimmune plasma nonspecifically enhances phagocytosis and intracellular killing of Rhodococcus equi

Author:
Harvey, Aja B.; Bordin, Angela I.; Rocha, Joana N.; Bray, Jocelyn M.; Cohen, Noah D.
Source:
Journal of veterinary internal medicine 2021 v.35 no.1 pp. 590-596
ISSN:
0891-6640
Subject:
phagocytosis,   etc   ; Rhodococcus equi; adults; macrophages; pneumonia; veterinary medicine;     Show all 6 Subjects
Abstract:
... BACKGROUND: Evidence regarding the efficacy of equine hyperimmune plasma to prevent pneumonia in foals caused by Rhodococcus equi is limited and conflicting. HYPOTHESIS: Opsonization with R. equi‐specific hyperimmune plasma (HIP) will significantly increase phagocytosis and decrease intracellular replication of R. equi by alveolar macrophages (AMs) compared to normal plasma (NP). ANIMALS: Fifteen ...
DOI:
10.1111/jvim.16002

16. Characterisation and functional role of a novel C1qDC protein from a colonial ascidian

Author:
A, Peronato; G, Minervini; M, Tabarelli; L, Ballarin; N, Franchi
Source:
Developmental and comparative immunology 2021 v.122 pp. 104077
ISSN:
0145-305X
Subject:
phagocytosis,   etc   ; Bacillus clausii; Botryllus schlosseri; complement; genes; immunocytes; invertebrates; lectins; signal peptide; transcriptome; vertebrates;     Show all 11 Subjects
Abstract:
... As an invertebrate, the compound ascidian Botryllus schlosseri faces nonself only with innate immunity. In this species, we already identified the key components of the lectin and alternative complement activation pathways. In the present work, by mining the transcriptome, we identified a single transcript codifying for a protein, member of the C1q-domain-containing protein family, with a signal p ...
DOI:
10.1016/j.dci.2021.104077

17. Structural characterization and immunomodulatory activity of intracellular polysaccharide from the mycelium of Paecilomyces cicadae TJJ1213

Author:
Tian, Juanjuan; Zhang, Cangping; Wang, Xiaomeng; Rui, Xin; Zhang, Qiuqin; Chen, Xiaohong; Dong, Mingsheng; Li, Wei
Source:
Food research international 2021 v.147 pp. 110515
ISSN:
0963-9969
Subject:
phagocytosis,   etc   ; Paecilomyces; cytokines; food research; galactose; glucose; immunomodulators; mannose; molecular weight; mycelium; nitric oxide; polysaccharides;     Show all 12 Subjects
Abstract:
... Two intracellular polysaccharide fractions (IPS1 and IPS2) were obtained from the mycelium of Paecilomyces cicadae TJJ1213, and the structures were conducted. Results showed that they were homogenous with the average molecular weight of 2.40 × 10⁶ Da and 6.79 × 10⁵ Da. Two fractions were composed of mannose, glucose and galactose with molar ratios of 1.35: 6.93: 1.0 and 2.04: 1.0: 1.87, respective ...
DOI:
10.1016/j.foodres.2021.110515

18. Blood polymorphonuclear leukocyte responses against Staphylococcus aureus in primiparous and pluriparous Lacaune and Santa Inês ewes

Author:
Sousa Marques, Michele Flávia; Santana de Moura, Guilherme; Nogueira de Souza, Fernando; Gomes Gargano, Ronaldo; Santos, Kamila Reis; Ferronatto, José Augusto; Della Libera, Alice Maria Melville Paiva; Mota, Rinaldo Aparecido
Source:
Small ruminant research 2021 v.201 pp. 106412
ISSN:
0921-4488
Subject:
phagocytosis,   etc   ; Staphylococcus aureus; farms; flow cytometry; fluorescence; reactive oxygen species; research; viability;     Show all 8 Subjects
Abstract:
... In this study, we evaluated the viability, intracellular production of reactive oxygen species (ROS) and phagocytosis of Staphylococcus aureus by blood polymorphonuclear leukocytes (PMNLs) in primiparous and pluriparous Santa Inês and Lacaune ewes. Blood was collected from 14 Santa Inês ewes (seven primiparous and seven pluriparous) and 14 Lacaune ewes (seven primiparous and seven pluriparous). Th ...
DOI:
10.1016/j.smallrumres.2021.106412

19. Immunomodulatory effect of intracellular polysaccharide from mycelia of Agaricus bitorquis (QuéL.) Sacc. Chaidam by TLR4-mediated MyD88 dependent signaling pathway

Author:
Lin, Ximeng; Li, Wenxia; Yuen, Hywel; Yuen, Michael; Peng, Qiang
Source:
International journal of biological macromolecules 2021 v.183 pp. 79-89
ISSN:
0141-8130
Subject:
phagocytosis,   etc   ; Agaricus bitorquis; edible fungi; gene expression; immunomodulators; mycelium; polysaccharides; viability; China;     Show all 9 Subjects
Abstract:
... Agaricus bitorquis (QuéL.) Sacc. Chaidam is a valuable edible fungus in Qinghai-Tibet plateau and ABSP is a novel intracellular polysaccharide from its mycelia. GC and NMR analysis determined ABSP is galactoglucomannan-like polysaccharide that may have immunomodulatory effect. This study used RAW264.7 as model cell to determine immunomodulatory effect of ABSP. After ABSP treatment, viability and p ...
DOI:
10.1016/j.ijbiomac.2021.04.120

20. Structures and anti-melanoma activities of two polysaccharides from Angelica sinensis (Oliv.) Diels

Author:
Zhang, Tian; Liu, Wenjuan; Fu, Chengyang; Qiao, Yuhe; Xiao, Kaimin; Ren, Li; Feng, Caixia; Wang, Jingmei; Yang, Weixia; Li, Xiao-Qiang; Cao, Wei
Source:
International journal of biological macromolecules 2021 v.183 pp. 972-981
ISSN:
0141-8130
Subject:
phagocytosis,   etc   ; Angelica sinensis; cytotoxicity; glucans; interleukin-2; macrophages; melanoma; molecular weight; splenocytes; therapeutics;     Show all 10 Subjects
Abstract:
... Polysaccharide is one of the necessary macromolecules in life activities, and it is also a very promising natural product for tumor prevention and treatment. In this study, two homogeneous polysaccharides (APS-4I and APS-4II) were isolated from Angelica sinensis (Oliv.) Diels. APS-4I was a linear glucan with molecular weight of 16.1 kDa, which was composed of 88.4% α-1,6-Glcp, 4.1% α-1,2-Glcp, 3.9 ...
DOI:
10.1016/j.ijbiomac.2021.05.021