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1. The Adaptiveness of Host Behavioural Manipulation Assessed Using Tinbergen’s Four Questions

Author:
Bhattarai, Upendra R.; Doherty, Jean-François; Dowle, Eddy; Gemmell, Neil J.
Source:
Trends in parasitology 2021 v.37 no.7 pp. 597-609
ISSN:
1471-4922
Subject:
phenotype,   etc   ; animal behavior; parasitology;     Show all 3 Subjects
Abstract:
... Host organisms show altered phenotypic reactions when parasitised, some of which result from adaptive host manipulation, a phenomenon that has long been debated. Here, we provide an overview and discuss the rationale in distinguishing adaptive versus nonadaptive host behavioural manipulation. We discuss Poulin’s criteria of adaptive host behavioural manipulation within the context of Tinbergen’s f ...
DOI:
10.1016/j.pt.2021.01.006

2. The complex role of genetic background in shaping the effects of spontaneous and induced mutations

Author:
Goldstein, Ilan; Ehrenreich, Ian M.
Source:
Yeast 2021 v.38 no.3 pp. 187-196
ISSN:
0749-503X
Subject:
phenotype,   etc   ; genetic background; yeasts;     Show all 3 Subjects
Abstract:
... Spontaneous and induced mutations frequently show different phenotypic effects across genetically distinct individuals. It is generally appreciated that these background effects mainly result from genetic interactions between the mutations and segregating loci. However, the architectures and molecular bases of these genetic interactions are not well understood. Recent work in a number of model org ...
DOI:
10.1002/yea.3530

3. Special Issue: “Bacteriophages and Biofilms”

Author:
Drulis-Kawa, Zuzanna; Maciejewska, Barbara
Source:
Viruses 2021 v.13 no.2
ISSN:
1999-4915
Subject:
phenotype,   etc   ; biofilm; physiology;     Show all 3 Subjects
Abstract:
... Biofilms are a community of surface-associated microorganisms characterized by the presence of different cell types in terms of physiology and phenotype [...] ...
DOI:
10.3390/v13020257

4. Efficient monitoring of phenology in chestnuts

Author:
Larue, Clément; Barreneche, Teresa; Petit, Rémy J.
Source:
Scientia horticulturae 2021 v.281 pp. 109958
ISSN:
0304-4238
Subject:
phenotype,   etc   ; Castanea; forests; fruits; phenology;     Show all 5 Subjects
Abstract:
... Chestnuts (Castanea spp.) are ecologically and economically important forest and fruit trees. They are cultivated for their nutritious nuts. To select varieties to be cultivated in chestnut orchards, their phenology needs to be considered. In this work, we adapt the international BBCH system to chestnuts by building on an existing phenological scale used in some European countries for these specie ...
DOI:
10.1016/j.scienta.2021.109958

5. Trait‐similarity and trait‐hierarchy jointly determine fine‐scale spatial associations of resident and invasive ant species

Author:
Wong, Mark K. L.; Tsang, Toby P. N.; Lewis, Owen T.; Guénard, Benoit
Source:
Ecography 2021 v.44 no.4 pp. 589-601
ISSN:
0906-7590
Subject:
phenotype,   etc   ; ; Solenopsis invicta; competitive exclusion;     Show all 4 Subjects
Abstract:
... Interspecific competition, a dominant process structuring ecological communities, is influenced by species' phenotypic differences. Limiting similarity theory holds that species with similar traits should compete intensely (‘trait‐similarity'). In contrast, competing theories including modern coexistence theory emphasize that species with traits conferring competitive advantages should outcompete ...
DOI:
10.1111/ecog.05505

6. From Genetic Maps to QTL Cloning: An Overview for Durum Wheat

Author:
Colasuonno, Pasqualina; Marcotuli, Ilaria; Gadaleta, Agata; Soriano, Jose Miguel
Source:
Plants 2021 v.10 no.2
ISSN:
2223-7747
Subject:
phenotype,   etc   ; durum wheat; quantitative traits;     Show all 3 Subjects
Abstract:
... Durum wheat is one of the most important cultivated cereal crops, providing nutrients to humans and domestic animals. Durum breeding programs prioritize the improvement of its main agronomic traits; however, the majority of these traits involve complex characteristics with a quantitative inheritance (quantitative trait loci, QTL). This can be solved with the use of genetic maps, new molecular mark ...
DOI:
10.3390/plants10020315

7. A Powerful Adaptive Cauchy-Variable Combination Method for Rare-Variant Association Analysis

Author:
Tang, Y.; Zhou, Y.; Chen, L.; Bao, Y.; Zhang, R.
Source:
Russian journal of genetics 2021 v.57 no.2 pp. 238-245
ISSN:
1022-7954
Subject:
phenotype,   etc   ; genetic analysis; genomics; statistics;     Show all 4 Subjects
Abstract:
... Set-based association analysis has emerged as a popular tool for testing the association of rare variants within a genomic region with complex diseases. However, when only a small proportion of variants are causal, combining the association signals of multiple markers within a genomic region may cause noise due to the inclusion of non-causal variants, which usually decreases the power of a test. B ...
DOI:
10.1134/S1022795421020125

8. RBM20-Associated Ventricular Arrhythmias in a Patient with Structurally Normal Heart

Author:
Vakhrushev, Yuriy; Kozyreva, Alexandra; Semenov, Andrey; Sokolnikova, Polina; Lubimtseva, Tamara; Lebedev, Dmitry; Smolina, Natalia; Zhuk, Sergey; Mitrofanova, Lubov; Vasichkina, Elena; Kostareva, Anna
Source:
Genes 2021 v.12 no.1
ISSN:
2073-4425
Subject:
phenotype,   etc   ; cardiomyopathy; genes; patients; sarcomeres;     Show all 5 Subjects
Abstract:
... RBM20 (RNA-binding motif protein 20) is a splicing factor targeting multiple cardiac genes, and its mutations cause cardiomyopathies. Originally, RBM20 mutations were discovered to cause the development of dilated cardiomyopathy by erroneous splicing of the gene TTN (titin). Titin is a giant protein found in a structure of the sarcomere that functions as a molecular spring and provides a passive s ...
DOI:
10.3390/genes12010094

9. Functional heterogeneity of mesenchymal stem cells from natural niches to culture conditions: implications for further clinical uses

Author:
Costa, Luis A.; Eiro, Noemi; Fraile, María; Gonzalez, Luis O.; Saá, Jorge; Garcia-Portabella, Pablo; Vega, Belén; Schneider, José; Vizoso, Francisco J.
Source:
Cellular and molecular life sciences 2021 v.78 no.2 pp. 447-467
ISSN:
1420-682X
Subject:
phenotype,   etc   ; extracellular matrix; medicine; therapeutics;     Show all 4 Subjects
Abstract:
... Mesenchymal stem cells (MSC) are present in all organs and tissues. Several studies have shown the therapeutic potential effect of MSC or their derived products. However, the functional heterogeneity of MSC constitutes an important barrier for transferring these capabilities to the clinic. MSC heterogeneity depends on their origin (biological niche) or the conditions of potential donors (age, dise ...
DOI:
10.1007/s00018-020-03600-0

10. Tau induces formation of α-synuclein filaments with distinct molecular conformations

Author:
Hojjatian, Alimohammad; Dasari, Anvesh K.R.; Sengupta, Urmi; Taylor, Dianne; Daneshparvar, Nadia; Yeganeh, Fatemeh Abbasi; Dillard, Lucas; Michael, Brian; Griffin, Robert G.; Borgnia, Mario J.; Kayed, Rakez; Taylor, Kenneth A.; Lim, Kwang Hun
Source:
Biochemical and biophysical research communications 2021 v.554 pp. 145-150
ISSN:
0006-291X
Subject:
phenotype,   etc   ; amyloid; atrophy; humans; plasticity; research;     Show all 6 Subjects
Abstract:
... Recent structural investigation of amyloid filaments extracted from human patients demonstrated that the ex vivo filaments associated with different disease phenotypes adopt diverse molecular conformations, which are different from those of in vitro amyloid filaments. A very recent cryo-EM structural study also revealed that ex vivo α-synuclein filaments extracted from multiple system atrophy pati ...
DOI:
10.1016/j.bbrc.2021.03.091

11. A molecular assay for rapidly distinguishing the AviPro SALMONELLA VAC T vaccine strain from wild-type field isolates

Author:
Ceyssens, Pieter-Jan; Van den Bossche, An; Phan, Lac Kim; Van Hoorde, Koenraad; Mattheus, Wesley
Source:
Journal of microbiological methods 2021 v.184 pp. 106190
ISSN:
0167-7012
Subject:
phenotype,   etc   ; Salmonella; antibiotic resistance; vaccines; virulence;     Show all 5 Subjects
Abstract:
... Rapid differentiation of the AviPro Salmonella VAC T strain from wild-type Salmonella ser. Typhimurium isolates is essential for the monitoring of veterinary isolates and targeted control actions. The distinction between the two strain types is routinely made by phenotypic antimicrobial resistance testing, but this sometime leads to ambiguous results with major economic implications. In this study ...
DOI:
10.1016/j.mimet.2021.106190

12. Human peripheral basophils extended phenotype shows a high expression of CD244 immuno-regulatory receptor

Author:
Berger, Anne-Emmanuelle; Durrieu, Coralie; Dzviga, Charles; Perrot, Jean-Luc; Lambert, Claude
Source:
Journal of immunological methods 2021 v.492 pp. 112951
ISSN:
0022-1759
Subject:
phenotype,   etc   ; complement; humans; hypersensitivity; immunomodulation; neoplasms;     Show all 6 Subjects
Abstract:
... Basophils play a major physio-pathological role in hypersensitivity related diseases. Basophils express high affinity Immunoglobulin (Ig) E receptors (FcεRI), IgG and complement regulatory. Basophils also have immunoregulatory activity through interaction with T cells. The aim of this study was to look for the expression of markers reflecting the activation status of peripheral Basophil in healthy ...
DOI:
10.1016/j.jim.2020.112951

13. Two new species of the genus Metapocyrtus Heller, 1912 (Coleoptera, Curculionidae, Entiminae, Pachyrhynchini), subgenus Orthocyrtus Heller, 1912, from Mindanao Island, Philippines

Author:
Cabras, Analyn A.; Medina, Milton Norman; Bollino, Maurizio
Source:
ZooKeys 2021 v.1029 pp. 139-154
ISSN:
1313-2970
Subject:
phenotype,   etc   ; Curculionidae; Philippines; new species; sympatry; urbanization;     Show all 6 Subjects
Abstract:
... Two new species of Metapocyrtus Heller, 1912, subgenus Orthocyrtus Heller, 1912 (Coleoptera, Curculionidae, Entiminae, Pachyrhynchini) are described and illustrated from Mindanao Island, Philippines. The species are Metapocyrtus (Orthocyrtus) davaoensissp. nov. and Metapocyrtus (Orthocyrtus) hirakuisp. nov. from Davao City and Bukidnon, respectively. Brief bionomical notes and phenotypic character ...
DOI:
10.3897/zookeys.1029.63023

14. Expanding the phenotype associated with interstitial 6p25.1p24.3 microdeletion: a new case and review of the literature

Author:
Tassano, Elisa; Uccella, Sara; Severino, Mariasavina; Giacomini, Thea; Nardi, Francesca; Gimelli, Giorgio; Tavella, Elisa; Ronchetto, Patrizia; Malacarne, Michela; Coviello, Domenico
Source:
Journal of genetics 2021 v.100 no.1 pp. 9
ISSN:
0022-1333
Subject:
phenotype,   etc   ; abdomen; children; genes; heart; karyotyping; patients;     Show all 7 Subjects
Abstract:
... Interstitial 6p25.1p24.3 microdeletions are rare events and a clear karyotype/phenotype correlation has not yet been determined. In this study, we present the clinical and molecular description of a child with a de novo 6p25.1p24.3 microdeletion, characterized by array-CGH, associated with mild intellectual disability, facial dysmorphisms, hypopigmentation of the skin of the abdomen, heart defects ...
DOI:
10.1007/s12041-021-01261-x

15. Mechanisms of meiotic drive in symmetric and asymmetric meiosis

Author:
Kruger, Alyssa N.; Mueller, Jacob L.
Source:
Cellular and molecular life sciences 2021 v.78 no.7 pp. 3205-3218
ISSN:
1420-682X
Subject:
phenotype,   etc   ; chromosomes; eggs; meiosis; meiotic drive;     Show all 5 Subjects
Abstract:
... Meiotic drive, the non-Mendelian transmission of chromosomes to the next generation, functions in asymmetric or symmetric meiosis across unicellular and multicellular organisms. In asymmetric meiosis, meiotic drivers act to alter a chromosome’s spatial position in a single egg. In symmetric meiosis, meiotic drivers cause phenotypic differences between gametes with and without the driver. Here we d ...
DOI:
10.1007/s00018-020-03735-0

16. Phenotype of the Aging-Dependent Spontaneous Onset of Hearing Loss in DBA/2 Mice

Author:
Seo, Min-Soo; Lee, Byeonghyeon; Kang, Kyung-Ku; Sung, Soo-Eun; Choi, Joo-Hee; Lee, Si-Joon; Kim, Young-In; Jung, Young-Suk; Kim, Un-Kyung; Kim, Kil Soo
Source:
Veterinary sciences 2021 v.8 no.3
ISSN:
2306-7381
Subject:
phenotype,   etc   ; animal models; brain stem; histopathology;     Show all 4 Subjects
Abstract:
... DBA/2 mice are a well-known animal model for hearing loss developed due to intrinsic properties of these animals. However, results on the phenotype of hearing loss in DBA/2 mice have been mainly reported at an early stage in mice aged ≤7 weeks. Instead, the present study evaluated the hearing ability at 5, 13, and 34 weeks of age using DBA/2korl mice. Auditory brainstem response test was performed ...
DOI:
10.3390/vetsci8030049

17. Revealing New Candidate Genes for Teat Number Relevant Traits in Duroc Pigs Using Genome-Wide Association Studies

Author:
Li, Yang; Pu, Lei; Shi, Liangyu; Gao, Hongding; Zhang, Pengfei; Wang, Lixian; Zhao, Fuping
Source:
Animals 2021 v.11 no.3
ISSN:
2076-2615
Subject:
phenotype,   etc   ; Duroc; Sus scrofa; chromosomes; genes; genomics;     Show all 6 Subjects
Abstract:
... The number of teats is related to the nursing ability of sows. In the present study, we conducted genome-wide association studies (GWAS) for traits related to teat number in Duroc pig population. Two mixed models, one for counted and another for binary phenotypic traits, were employed to analyze seven traits: the right (RTN), left (LTN), and total (TTN) teat numbers; maximum teat number on a side ...
DOI:
10.3390/ani11030806

18. Case contamination in electronic health records based case‐control studies

Author:
Wang, Lu; Schnall, Jill; Small, Aeron; Hubbard, Rebecca A.; Moore, Jason H.; Damrauer, Scott M.; Chen, Jinbo
Source:
Biometrics 2021 v.77 no.1 pp. 67-77
ISSN:
0006-341X
Subject:
phenotype,   etc   ; data collection; equations; odds ratio; telemedicine;     Show all 5 Subjects
Abstract:
... Clinically relevant information from electronic health records (EHRs) permits derivation of a rich collection of phenotypes. Unlike traditionally designed studies where scientific hypotheses are specified a priori before data collection, the true phenotype status of any given individual in EHR‐based studies is not directly available. Structured and unstructured data elements need to be queried thr ...
DOI:
10.1111/biom.13264

19. Whole Exome Sequencing Reveals a Novel AUTS2 In-Frame Deletion in a Boy with Global Developmental Delay, Absent Speech, Dysmorphic Features, and Cerebral Anomalies

Author:
Palumbo, Pietro; Di Muro, Ester; Accadia, Maria; Benvenuto, Mario; Di Giacomo, Marilena Carmela; Castellana, Stefano; Mazza, Tommaso; Castori, Marco; Palumbo, Orazio; Carella, Massimo
Source:
Genes 2021 v.12 no.2
ISSN:
2073-4425
Subject:
phenotype,   etc   ; autism; boys; cerebellum; cognition; patients; speech;     Show all 7 Subjects
Abstract:
... Neurodevelopmental disorders (NDDs) are a group of highly prevalent, clinically and genetically heterogeneous pediatric disorders comprising, according to the Diagnostic and Statistical Manual of Mental Disorders 5th edition (DSM-V), intellectual disability, developmental delay, autism spectrum disorders, and other neurological and cognitive disorders manifesting in the developmental age. To date, ...
DOI:
10.3390/genes12020229

20. ARF4 regulates shoot regeneration through coordination with ARF5 and IAA12

Author:
Zhang, Miao Miao; Zhang, Huan Kai; Zhai, Jun Feng; Zhang, Xian Sheng; Sang, Ya Lin; Cheng, Zhi Juan
Source:
Plant cell reports 2021 v.40 no.2 pp. 315-325
ISSN:
0721-7714
Subject:
phenotype,   etc   ; auxins; mutants; repressor proteins; shoot meristems;     Show all 5 Subjects
Abstract:
... KEY MESSAGE: ARF4-regulated shoot regeneration through competing with ARF5 for the interaction with IAA12. Plant possess the ability to regenerate shoot meristem and subsequent the whole individual. This process is the foundation for in vitro propagation and genetic engineering and provides a system for studying fundamental biological questions, such as hormonal signaling. Auxin response factor (A ...
DOI:
10.1007/s00299-020-02633-w