PubAg

Main content area

You searched for: Subject "phospholipids" Remove constraint Subject: "phospholipids"
Start Over

Search

8,742  Search Results

« Previous | 1 - 20 of 8,742 |
Number of results to display per page

Search Results

1. Born this way – Biogenesis of lipid droplets from specialized ER subdomains

Author:
Nettebrock, Niclas T.; Bohnert, Maria
Source:
Biochimica et biophysica acta 2020 v.1865 no.1 pp. 158448
ISSN:
1388-1981
Subject:
phospholipids,   etc   ; biogenesis; droplets; endoplasmic reticulum; proteins;     Show all 5 Subjects
Abstract:
... Both the endoplasmic reticulum (ER) and lipid droplets (LDs) are key players in lipid handling. In addition to this functional connection, the two organelles are also tightly linked due to the fact that the ER is the birthplace of LDs. LDs have an atypical architecture, consisting of a neutral lipid core that is covered by a phospholipid monolayer. LD biogenesis starts with neutral lipid synthesis ...
DOI:
10.1016/j.bbalip.2019.04.008

2. A lipid mixing assay to accurately quantify the fusion of outer membrane vesicles

Author:
Gnopo, Yehou M.D.; Putnam, David
Source:
Methods 2020 v.177 pp. 74-79
ISSN:
1046-2023
Subject:
phospholipids,   etc   ; Escherichia coli; chlorides; membrane fusion; mixing; quantitative analysis;     Show all 6 Subjects
Abstract:
... The intermixing of phospholipids from opposing bilayers, or membrane fusion, is a naturally occurring process that can be leveraged to produce hybrid vesicle systems. Optimizing the production of these hybrid vesicles requires accurate, sensitive, and quantitative methods of the lipid mixing that occurs during fusion. A fluorescence-based assay that uses octadecyl-rhodamine B chloride to measure l ...
DOI:
10.1016/j.ymeth.2019.11.009

3. Mechanical and transport properties of chitosan-zwitterionic phospholipid vesicles

Author:
James, Honey Priya; Jadhav, Sameer
Source:
Colloids and surfaces 2020 v.188 pp. 110782
ISSN:
0927-7765
Subject:
phospholipids,   etc   ; biodegradability; chitosan; diffusivity; drugs; lipid bilayers; pH; permeability; toxicity;     Show all 9 Subjects
Abstract:
... Chitosan is a polysaccharide that has shown promise in liposomal drug delivery because of certain desirable properties such as muco-adhesivity, biodegradability and low toxicity. In this study, chitosan-bearing 1-stearoyl-2-oleoyl-sn-glycero-3-phosphocholine giant unilamellar vesicles were prepared using inverse phase precursor method to measure their mechanical and transport properties. We show t ...
DOI:
10.1016/j.colsurfb.2020.110782

4. Confocal Raman Microscopy Investigation of Phospholipid Monolayers Deposited on Nitrile-Modified Surfaces in Porous Silica Particles

Author:
Bryce, David A.; Kitt, Jay P.; Myres, Grant J.; Harris, Joel M.
Source:
Langmuir 2020 v.36 no.15 pp. 4071-4079
ISSN:
1520-5827
Subject:
phospholipids,   etc   ; Raman imaging; chromatography; ligands; melting; silica; surface area; temperature;     Show all 8 Subjects
Abstract:
... Phospholipid bilayers deposited on a variety of surfaces provide models for investigation of the lipid membrane structure and supports for biocompatible sensors. Hybrid-supported phospholipid bilayers (HSLBs) are stable membrane models for these investigations, typically prepared by self-assembly of a lipid monolayer over an n-alkane-modified surface. HSLBs have been prepared on n-alkyl chain-modi ...
DOI:
10.1021/acs.langmuir.0c00456

5. Reconstitution of the heliobacterial photochemical reaction center and cytochrome c553 into a proteoliposome system

Author:
Johnson, William A.; Redding, Kevin E.
Source:
Photosynthesis research 2020 v.143 no.3 pp. 241-250
ISSN:
0166-8595
Subject:
phospholipids,   etc   ; binding sites; diacylglycerols; nickel; oxidation; photochemical reactions; polypeptides;     Show all 7 Subjects
Abstract:
... The heliobacterial reaction center (HbRC) is the simplest known photochemical reaction center, in terms of its polypeptide composition. In the heliobacterial cells, its electron donor is a cytochrome (cyt) c₅₅₃ attached to the membrane via a covalent linkage with a diacylglycerol. We have reconstituted purified HbRC into liposomes mimicking the phospholipid composition of heliobacterial membranes. ...
DOI:
10.1007/s11120-019-00695-w

6. Effect of H₃O⁺ on the Structure and Dynamics of Water at the Interface with Phospholipid Bilayers

Author:
Deplazes, Evelyne; Sarrami, Farzaneh; Poger, David
Source:
TheJournal of physical chemistry 2020 v.124 no.8 pp. 1361-1373
ISSN:
1520-5207
Subject:
phospholipids,   etc   ; hydrogen bonding; ions; molecular dynamics; probability; simulation models;     Show all 6 Subjects
Abstract:
... This study investigates the effect of hydronium ions (H₃O⁺) on the structure and dynamics of water at the interface of a phospholipid bilayer using molecular dynamics simulations of a POPC bilayer in the presence and absence of H₃O⁺ ions. From these simulations, the survival probability, hydrogen bond lifetimes, orientation relaxation, and angular distribution of interfacial water, at increasing d ...
DOI:
10.1021/acs.jpcb.9b10169

7. Tools for Understanding Nanoscale Lipid Regulation of Ion Channels

Author:
Robinson, Carol V.; Rohacs, Tibor; Hansen, Scott B.
Source:
Trends in biochemical sciences 2019 v.44 no.9 pp. 795-806
ISSN:
0968-0004
Subject:
phospholipids,   etc   ; ion channels; plasma membrane;     Show all 3 Subjects
Abstract:
... Anionic phospholipids are minor but prominent components of the plasma membrane that are necessary for ion channel function. Their persistence in bulk membranes, in particular phosphatidylinositol 4,5-bisphosphate (PIP2), initially suggested they act as channel cofactors. However, recent technologies have established an emerging system of nanoscale signaling to ion channels based on lipid compartm ...
DOI:
10.1016/j.tibs.2019.04.001
PubMed:
31060927
PubMed Central:
PMC6729126

8. Biological Macrocycle: Supramolecular Hydrophobic Guest Transport System Based on Nanodiscs with Photodynamic Activity

Author:
Ge, Yan; Shen, Xin; Cao, Hongqian; Jin, Lin; Shang, Jie; Wang, Yangxin; Pan, Tiezheng; Yang, Yang; Qi, Zhenhui
Source:
Langmuir 2019 v.35 no.24 pp. 7824-7829
ISSN:
1520-5827
Subject:
phospholipids,   etc   ; hydrophobicity; scaffolding proteins; solubility;     Show all 4 Subjects
Abstract:
... A biogenic macrocycle-based guest loading system has been developed by the self-assembly of membrane scaffold protein and phospholipids. The resulting 10 nm level transport system can increase the solubility of hydrophobic photodynamic agent hypocrellin B in aqueous medium and exhibited a cellular internalization capacity with substantial photodynamic activity. ...
DOI:
10.1021/acs.langmuir.9b00126

9. Measuring the passive cuticular membrane permeability of potassium with a parallel artificial membrane permeability assay and the implications for foliar nutrient formulations

Author:
He, Qingwen; Rezai, Taha
Source:
Chemical and biological technologies in agriculture 2020 v.7 no.1 pp. 4
ISSN:
2196-5641
Subject:
phospholipids,   etc   ; animal models; membrane permeability; nutrients; organic matter; plant cuticle; potassium; structure-activity relationships;     Show all 8 Subjects
Abstract:
... A modified PAMPA (parallel artificial membrane permeability assay) is proposed for evaluating the passive cuticular membrane permeability of potassium in several foliar nutrient formulations. The modified PAMPA can measure the passive permeability of ionic nutrients under fully hydrated conditions through an artificial membrane designed to more closely resemble a plant cuticle, rather than the tra ...
DOI:
10.1186/s40538-019-0166-z

10. The ABCA1 blocking agent probucol decreases capacitation in ejaculated dog spermatozoa

Author:
Schäfer-Somi, Sabine; Budik, Sven
Source:
Acta veterinaria scandinavica 2020 v.62 no.1 pp. 2
ISSN:
1751-0147
Subject:
phospholipids,   etc   ; ABC transporters; acrosome; cell membranes; cholesterol; colorimetry; dogs; epididymis; probucol; ripening; sperm capacitation; staining; viability;     Show all 13 Subjects
Abstract:
... BACKGROUND: The ATP binding cassette (ABC) transporters participate in the cholesterol and phospholipid transport within and through cell membranes of many cells including spermatozoa. Cholesterol efflux is important for capacitation of spermatozoa. ABCA1 expression has been assessed in canine spermatozoa previously but its role in capacitation still has to be determined. The aim of the study was ...
DOI:
10.1186/s13028-019-0500-2
PubMed:
31907058
PubMed Central:
PMC6945687

11. Influence of hydrophobic Au nanoparticles on SOPC lipid model systems

Author:
Slavkova, Z.; Genova, J.; Chamati, H.; Koroleva, M.; Yancheva, D.
Source:
Colloids and surfaces 2020 v.603 pp. 125090
ISSN:
0927-7757
Subject:
phospholipids,   etc   ; differential scanning calorimetry; drug delivery systems; gold; hydrophobicity; infrared spectroscopy; models; modulus of elasticity; nanogold;     Show all 9 Subjects
Abstract:
... We examine the effect of hydrophobic gold nanoparticles in concentrations 0.5, 1, 5 w% on 1-Stearoyl-2-oleoyl-sn-glycero-3-phosphocholine (SOPC) model systems. To this aim, we used advanced experimental techniques, such as differential scanning calorimetry and infrared spectroscopy. An estimation of the bending elasticity modulus (kc) of vesicles with Au is achieved using the thermally induced sha ...
DOI:
10.1016/j.colsurfa.2020.125090

12. Plasmalogen fingerprint alteration and content reduction in beef during boiling, roasting, and frying

Author:
Wu, Yue; Chen, Zhen; Chiba, Hitoshi; Hui, Shu-Ping
Source:
Food chemistry 2020 v.322 pp. 126764
ISSN:
0308-8146
Subject:
phospholipids,   etc   ; beef; boiling; frying; liquid chromatography; neural networks; roasting; spectroscopy; temperature;     Show all 9 Subjects
Abstract:
... Plasmalogens are dietary phospholipids with beneficial health effects. In this work, plasmalogen characteristics and changes in beef during boiling, frying, and roasting were comprehensively investigated by liquid-chromatography-mass spectrometry. The alteration of plasmalogen fingerprint during cooking processes was found by untargeted omics approach, in which time of boiling, temperature of roas ...
DOI:
10.1016/j.foodchem.2020.126764

13. Adsorption of a styrene maleic acid (SMA) copolymer-stabilized phospholipid nanodisc on a solid-supported planar lipid bilayer

Author:
Hall, Stephen C.L.; Clifton, Luke A.; Tognoloni, Cecilia; Morrison, Kerrie A.; Knowles, Timothy J.; Kinane, Christian J.; Dafforn, Tim R.; Edler, Karen J.; Arnold, Thomas
Source:
Journal of colloid and interface science 2020 v.574 pp. 272-284
ISSN:
0021-9797
Subject:
phospholipids,   etc   ; adsorption; composite polymers; lipid bilayers; maleic acid; membrane proteins; polymerization; styrene; surfactants;     Show all 9 Subjects
Abstract:
... Over recent years, there has been a rapid development of membrane-mimetic systems to encapsulate and stabilize planar segments of phospholipid bilayers in solution. One such system has been the use of amphipathic copolymers to solubilize lipid bilayers into nanodiscs. The attractiveness of this system, in part, stems from the capability of these polymers to solubilize membrane proteins directly fr ...
DOI:
10.1016/j.jcis.2020.04.013

14. Size Measurement of Extracellular Vesicles and Synthetic Liposomes: The Impact of the Hydration Shell and the Protein Corona

Author:
Varga, Zoltán; Fehér, Bence; Kitka, Diána; Wacha, András; Bóta, Attila; Berényi, Szilvia; Pipich, Vitaliy; Fraikin, Jean-Luc
Source:
Colloids and surfaces 2020 v.192 pp. 111053
ISSN:
0927-7765
Subject:
phospholipids,   etc   ; blood; drugs; hydrodynamics; light scattering; nanoparticles; neutron diffraction; particle size; polyethylene; protein corona; therapeutics;     Show all 11 Subjects
Abstract:
... Size characterization of extracellular vesicles (EVs) and drug delivery liposomes is of great importance in their applications in diagnosis and therapy of diseases. There are many different size characterization techniques used in the field, which often report different size values. Besides technological biases, these differences originate from the fact that various methods measure different physi ...
DOI:
10.1016/j.colsurfb.2020.111053

15. The role of lipids in determining the air-water interfacial properties of wheat, rye, and oat dough liquor constituents

Author:
Janssen, Frederik; Wouters, Arno G.B.; Linclau, Lize; Waelkens, Etienne; Derua, Rita; Dehairs, Jonas; Moldenaers, Paula; Vermant, Jan; Delcour, Jan A.
Source:
Food chemistry 2020 v.319 pp. 126565
ISSN:
0308-8146
Subject:
phospholipids,   etc   ; breadmaking; breads; defatting; dough; oats; proteins; rye; surface tension; viscosity; wheat;     Show all 11 Subjects
Abstract:
... Bread is mainly made from wheat but also from other cereals such as rye and oats. We here report on the role of dough liquor (DL) proteins and lipids in determining the stability of gas cell air-water (A-W) interfaces in wheat, rye, and oat bread making. Surprisingly, most lipids in DLs of these cereals are nonpolar. Their main polar DL lipids are phospholipids. Lipids at wheat and rye DL stabiliz ...
DOI:
10.1016/j.foodchem.2020.126565

16. In situ and real-time authentication of Thunnus species by iKnife rapid evaporative ionization mass spectrometry based lipidomics without sample pretreatment

Author:
Song, Gongshuai; Chen, Kang; Wang, Haixing; Zhang, Mengna; Yu, Xina; Wang, Jie; Shen, Qing
Source:
Food chemistry 2020 v.318 pp. 126504
ISSN:
0308-8146
Subject:
phospholipids,   etc   ; Thunnus; adulterated products; biomarkers; fatty acids; financial economics; mass spectrometry; rapid methods; tuna;     Show all 9 Subjects
Abstract:
... Tuna adulteration and mislabeling are serious problem worldwide and have caused economic loss and consumer rights violation. In this study, an electrometric knife (iKnife) coupling rapid evaporative ionization mass spectrometry (REIMS) and a multivariate recognition model were developed and employed for in situ and real-time authentication of four tuna species without sample preparation. The resul ...
DOI:
10.1016/j.foodchem.2020.126504

17. Influence of calcium fortification on physicochemical properties of whey protein concentrate solutions enriched in α-lactalbumin

Author:
Barone, Giovanni; Moloney, Cian; O'Regan, Jonathan; Kelly, Alan L.; O'Mahony, James A.
Source:
Food chemistry 2020 v.317 pp. 126412
ISSN:
0308-8146
Subject:
phospholipids,   etc   ; calcium; calcium chloride; ingredients; ion exchange chromatography; lactalbumin; microfiltration; physicochemical properties; whey protein concentrate;     Show all 9 Subjects
Abstract:
... In this study, three whey protein concentrate systems enriched in α-lactalbumin, produced using membrane filtration (LAC-M), selective precipitation (LAC-P) and ion-exchange chromatography (LAC-IE), were fortified with calcium chloride (CaCl₂) at 0–5 mM and changes in physicochemical properties studied. Binding of calcium (Ca²⁺) occurred for LAC-P in the range 0.00–2.00 mM, with an affinity consta ...
DOI:
10.1016/j.foodchem.2020.126412

18. A simple chemo-enzymatic synthesis of alkyl-acyl (plasmanyl) phospholipids

Author:
Iwasaki, Yugo; Sakurai, Yuuki; Damnjanović, Jasmina
Source:
Biocatalysis and agricultural biotechnology 2020 v.26 pp. 101625
ISSN:
1878-8181
Subject:
phospholipids,   etc   ; alkylation; choline; esterification; fatty acids; liquid chromatography; mass spectrometry; moieties; phospholipase A2; phospholipase D; phospholipases;     Show all 11 Subjects
Abstract:
... Here we describe a novel, simple and general approach for the preparation of various plasmanyl phospholipids (PLs). In the past, synthesis of plasmanyl-PLs mostly relied on two types of synthetic routes, both being costly and laborious, multi-step processes. We propose a three-step method, free of protection/deprotection steps, affording plasmanyl-PLs with a variety of polar heads. The simplicity ...
DOI:
10.1016/j.bcab.2020.101625

19. Nanoarchitectronics: A versatile tool for deciphering nanoparticle interaction with cellular proteins, nucleic acids and phospholipids at biological interfaces

Author:
Mutalik, Sadhana P.; Pandey, Abhijeet; Mutalik, Srinivas
Source:
International journal of biological macromolecules 2020 v.151 pp. 136-158
ISSN:
0141-8130
Subject:
phospholipids,   etc   ; adhesion; biomedical research; drugs; energy metabolism; nanocarriers; nanoparticles; nucleic acids; proteins; sensors (equipment);     Show all 10 Subjects
Abstract:
... Nano-Bio interface involves the dynamic interactions of nanomaterial and a living system. Association of nanotechnology and biology has been a valuable tool in improving the potentials of biomedical research. Exquisite structures of nanoparticles comparable in size with biomolecules and the unique possibility of tuning their chemical and physical functionality at small length scales make them more ...
DOI:
10.1016/j.ijbiomac.2020.02.150

20. High-sensitivity detection of therapeutic drugs in complex biofluids using a packed ballpoint-electrospray ionization technique

Author:
Fu, Xian; Qin, Yongping; Xia, Bing; Wang, Yu; Shi, Peiyu; Zhou, Yan
Source:
Analytical and bioanalytical chemistry 2020 v.412 no.12 pp. 2711-2720
ISSN:
1618-2642
Subject:
phospholipids,   etc   ; adsorbents; blood plasma; blood sampling; drugs; electric potential difference; electrical conductivity; electrodes; ionization; therapeutics; urine;     Show all 11 Subjects
Abstract:
... A simple and sensitive C₁₈ packed ballpoint-electrospray ionization (PBP-ESI) technique was developed for biofluid analysis. In this technique, the configuration of a commercial ballpoint consisting of a hollow chamber, an intermediate socket, and a metal ball was fully exploited. The rear-end hollow chamber was used for loading C₁₈ adsorbent and sample, and the front metal ball served as a spray ...
DOI:
10.1007/s00216-020-02512-z