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1. Two new abietane diterpenoids from the leaves of Rabdosia serra

Author:
Liu, Gui-Lian; Xu, Wei; Liu, Xin-Juan; Yan, Xue-Long; Chen, Jie
Source:
Journal of Asian natural products research 2020 v.22 no.1 pp. 47-51
ISSN:
1477-2213
Subject:
phytochemicals,   etc   ; Isodon (Lamiaceae); diterpenoids; leaves; moieties; phenylpropanoids; spectral analysis;     Show all 7 Subjects
Abstract:
... Phytochemical investigation on the leaves of Rabdosia serra led to the isolation of two new abietane diterpenoids, raserranes A (1) and B (2), and four known phenylpropanoids (3–6). Their structures were determined by spectroscopic data. Compound 1 represented the rare examples of abietane diterpenoids featuring a 16-methoxycarbonyl group. ...
DOI:
10.1080/10286020.2018.1539081

2. Vegetables from the Cucurbitaceae family and their products: Positive effect on human health

Author:
Rolnik, Agata; Olas, Beata
Source:
Nutrition 2020 v.78 pp. 110788
ISSN:
0899-9007
Subject:
phytochemicals,   etc   ; Cucurbitaceae; antioxidants; carotenoids; crops; cucumbers; human health; pumpkins; purgative properties; saponins; seeds;     Show all 11 Subjects
Abstract:
... The Cucurbitaceae family is a large group of crops with more than 800 species known worldwide. Vegetables from this family have been used for centuries, not only for consumption, but also for their medicinal value. The most characteristic cucurbits are pumpkin and cucumber, which are cultivated and consumed in many parts of the world. Seeds from cucurbits have many health benefits and are a popula ...
DOI:
10.1016/j.nut.2020.110788

3. Assessment of secondary metabolite profile and quantification method development for Lupeol and Caffeic acid by HPTLC in Avicennia marina pneumatophore roots

Author:
Dawane, Vinars; Pathak, Bhawana
Source:
Biocatalysis and agricultural biotechnology 2020 v.26 pp. 101573
ISSN:
1878-8181
Subject:
phytochemicals,   etc   ; Avicennia marina; bioactive compounds; biotechnology; caffeic acid; ingredients; lupeol; nanobiotechnology; pharmacognosy; pneumatophores; secondary metabolites;     Show all 11 Subjects
Abstract:
... It has been strongly endorsed that mangroves should be considered as a treasured source for phytochemical ingredients with potential medicinal, environmental, agricultural, biotechnological and nanobiotechnological applications. They are able to produce lots of natural structures, significant enough for widely acceptable in today's scenario, to generate various commercial and valuable products. Th ...
DOI:
10.1016/j.bcab.2020.101573

4. Dihydroagarofuran sesquiterpene derivatives from the stems of Tripterygium hypoglaucum and activity evaluation

Author:
Lu, Li-He; Lu, Xue-Ping; Guo, Yan; Mei, Shuang-Xi; Li, Xiao-Hui
Source:
Tetrahedron letters 2020 v.61 no.25 pp. 151992
ISSN:
0040-4039
Subject:
phytochemicals,   etc   ; Tripterygium; anti-inflammatory activity; chemical reactions; chemical structure; sesquiterpenoids; spectroscopy; stems;     Show all 8 Subjects
Abstract:
... Phytochemical investigation of an extract of the stems of Tripterygium hypoglaucum resulted in the identification of five undescribed dihydroagarofuran sesquiterpene derivatives, namely as hypoterpenes A-E (1–5). On the basis of the comprehensive spectroscopic experiments, their structures were elucidated. All isolated compounds were assayed for anti-inflammatory activities. ...
DOI:
10.1016/j.tetlet.2020.151992

5. Cassane and nor-cassane diterpenoids from the roots of Erythrophleum fordii

Author:
Li, Lulu; Chen, Long; Li, Yuhuan; Sun, Shikai; Ma, Shuanggang; Li, Yong; Qu, Jing
Source:
Phytochemistry 2020 v.174 pp. 112343
ISSN:
0031-9422
Subject:
phytochemicals,   etc   ; Enterovirus; Erythrophleum fordii; Orthomyxoviridae; antiviral properties; diterpenoids; inhibitory concentration 50; nuclear magnetic resonance spectroscopy; roots;     Show all 9 Subjects
Abstract:
... Detailed phytochemical investigation of the roots of Erythrophleum fordii furnished seven undescribed cassane-type diterpenoids, erythrocassanoids A-E and erythro-norcassanoids A, B and two known clerodane diterpenes, 15-hydroxy-3-cleroden-2-one and methyl ester of 2-oxopopulifolic acid. Their structures were determined by 1D, 2D NMR and HRESIMS analysis. The antiviral activities of these compound ...
DOI:
10.1016/j.phytochem.2020.112343

6. Ethnopharmacological survey of herbal remedies used for treating malaria in Yemen

Author:
Al-Adhroey, Abdulelah H.; Al-Abhar, Yahya M.; Noman, Nahlah M.; Al-Mekhlafi, Hesham M.
Source:
Journal of herbal medicine 2020 v.21 pp. 100332
ISSN:
2210-8033
Subject:
phytochemicals,   etc   ; antimalarials; databases; herbal medicines; malaria; questionnaires; surveys; traditional medicine; Yemen;     Show all 9 Subjects
Abstract:
... This is the first ethnopharmacological survey among traditional healers in Yemen that has been conducted to investigate the herbal remedies used in the treatment of malaria. Sixteen traditional healers from three governorates in Yemen participated in this survey in which a pre-tested questionnaire was used to collect information on the herbal remedies used for the treatment of malaria. Overall, 18 ...
DOI:
10.1016/j.hermed.2020.100332

7. Alkaloid and iridoid glucosides from Palicourea luxurians (Rubiaceae: Palicoureeae) indicate tryptamine- and tryptophan-iridoid alkaloid formation apart the strictosidine pathway

Author:
Kornpointner, Christoph; Berger, Andreas; Traxler, Florian; Hadžiabdić, Azra; Massar, Magdalena; Matek, Joanna; Brecker, Lothar; Schinnerl, Johann
Source:
Phytochemistry 2020 v.173 pp. 112296
ISSN:
0031-9422
Subject:
phytochemicals,   etc   ; Palicourea; alkaloids; bark; biochemical pathways; biosynthesis; carbon; enzymes; leaf extracts; loganin; reaction mechanisms; tryptamine; tryptophan;     Show all 13 Subjects
Abstract:
... The first phytochemical examination of extracts from leaves and stem bark of Palicourea luxurians (Rusby) Borhidi yielded two undescribed and one known alstrostine derivative together with the oxindole alkaloid javaniside as well as with 5α-carboxystrictosidine. Additionally, five iridoids and four secologanin derived isolation artifacts have been isolated. Lack of strictosidine and its follow-up ...
DOI:
10.1016/j.phytochem.2020.112296

8. High-humidity hot air impingement blanching (HHAIB) efficiently inactivates enzymes, enhances extraction of phytochemicals and mitigates brown actions of chili pepper

Author:
Wang, Hui; Zhang, Qian; Mujumdar, A.S.; Fang, Xiao-Ming; Wang, Jun; Pei, Yu-Peng; Wu, Wei; Zielinska, Magdalena; Xiao, Hong-Wei
Source:
Food control 2020 v.111 pp. 107050
ISSN:
0956-7135
Subject:
phytochemicals,   etc   ; air; ascorbic acid; blanching; hot peppers; pepper; peroxidase; relative humidity; response surface methodology; temperature;     Show all 10 Subjects
Abstract:
... In current work, high-humidity hot air impingement blanching (HHAIB) was employed to inactivate peroxidase enzymes (POD) of chili pepper under three independent variables, namely blanching temperature (105, 110, and 115 °C), relative humidity (20%, 30%, and 40%), and blanching time (30, 60, and 90 s). Response surface methodology (RSM) was used to optimize the blanching conditions based on product ...
DOI:
10.1016/j.foodcont.2019.107050

9. Enumeration of various Ayurvedic formulations listed in an ancient palm-leaf manuscript of Rayalaseema region in Andhra Pradesh state, India

Author:
Chandramouli, Balaraju; Mallikarjuna, Kokkanti
Source:
Journal of ethnopharmacology 2020 v.251 pp. 112552
ISSN:
0378-8741
Subject:
phytochemicals,   etc   ; Ayurvedic medicine; animal products; databases; drugs; human health; management systems; metals; minerals; plant products; India;     Show all 11 Subjects
Abstract:
... Ancient India relied on manuscripts written by scholars for storing, transferring and retrieving the information pertaining to culture, traditions, religion, geography and political issues. Similarly, Ayurveda, an ancient human health care management system in India and most of its information is available through palm-leaf manuscripts. Though each palm-leaf can persist for a fairly long time, it ...
DOI:
10.1016/j.jep.2020.112552

10. Biotechnological production of betulinic acid and derivatives and their applications

Author:
An, Tianyue; Zha, Wenlong; Zi, Jiachen
Source:
Applied microbiology and biotechnology 2020 v.104 no.8 pp. 3339-3348
ISSN:
0175-7598
Subject:
phytochemicals,   etc   ; Betula; antiretroviral properties; betulin; betulinic acid; biochemical pathways; biosynthesis; endoplasmic reticulum; hosts;     Show all 9 Subjects
Abstract:
... Betulinic acid (BA), a lupane-type triterpenoid, mainly distributes in birch plants. It has been reported that BA and its derivatives possess potent anticancer and anti-HIV activities. Commercial production of BA to date depends on phytochemical extraction and semi-synthesis from betulin (a biosynthetic precursor of BA). The biosynthetic pathway of BA has been completely revealed so far. The relev ...
DOI:
10.1007/s00253-020-10495-1

11. Bioaccessibility of curcumin encapsulated in yeast cells and yeast cell wall particles

Author:
Young, Stephen; Rai, Rewa; Nitin, Nitin
Source:
Food chemistry 2020 v.309 pp. 125700
ISSN:
0308-8146
Subject:
phytochemicals,   etc   ; bile salts; bioavailability; cell walls; curcumin; encapsulation; image analysis; in vitro digestion; intestines; yeasts;     Show all 10 Subjects
Abstract:
... This study evaluates the role of intracellular composition and integrity of cell walls in modulating the release and bioaccessibility of phytochemicals during simulated gastrointestinal digestion of cell-based carriers. Native yeast and yeast cell wall particles (YCWPs) were used as model cell-based carriers with distinct intracellular composition and curcumin was a model encapsulated bioactive. T ...
DOI:
10.1016/j.foodchem.2019.125700

12. Emerging promise of sulforaphane-mediated Nrf2 signaling cascade against neurological disorders

Author:
Uddin, Md. Sahab; Mamun, Abdullah Al; Jakaria, Md.; Thangapandiyan, Shanmugam; Ahmad, Jamil; Rahman, Md. Ataur; Mathew, Bijo; Abdel-Daim, Mohamed M.; Aleya, Lotfi
Source:
The Science of the total environment 2020 v.707 pp. 135624
ISSN:
0048-9697
Subject:
phytochemicals,   etc   ; antioxidants; death; mitochondria; neurodegenerative diseases; neurons; oxidative stress; protein folding; sulforaphane;     Show all 9 Subjects
Abstract:
... Neurological disorders represent a great challenge and are the leading cause of death and disability globally. Although numerous complicated mechanisms are involved in the progressions of chronic and acute neurodegenerative disorders, most of the diseases share mutual pathogenic features such as oxidative stress, mitochondrial dysfunction, neuroinflammation, protein misfolding, excitotoxicity, and ...
DOI:
10.1016/j.scitotenv.2019.135624

13. Secondary metabolites from the fungus Stereum gausapatum ATCC60954

Author:
Huang, Jun-Ran; Yang, Bang-Ju; Mo, Ming-He; Zhang, Ke-Qin; Li, Guo-Hong
Source:
Phytochemistry letters 2020 v.35 pp. 171-174
ISSN:
1874-3900
Subject:
phytochemicals,   etc   ; Nematoda; Stereum; chemical composition; fungi; mortality; secondary metabolites; spectral analysis;     Show all 8 Subjects
Abstract:
... A phytochemical investigation of basidiomycete Stereum gausapatum ATCC60954 led to the isolation of five compounds. They are determined to be strobilol N (1), strobilol O (2), strobilol P (3), strobilol E (4) and stereumin D (5) based on the spectral data. Compounds 1-3 are new metabolites. Compound 1 was active against nematode Caenorhabditiselegans with the mortality 75.8 % at 200 μg/ml in 36 h. ...
DOI:
10.1016/j.phytol.2019.12.004

14. Impact of aminated carbon quantum dots as a novel co-reactant for Ru(bpy)32+: resolving specific electrochemiluminescence for butein detection

Author:
Kalaiyarasan, Gopi; Raju, Chikkili Venkateswara; Veerapandian, Murugan; Kumar, Shanmugam Senthil; Joseph, James
Source:
Analytical and bioanalytical chemistry 2020 v.412 no.3 pp. 539-546
ISSN:
1618-2642
Subject:
phytochemicals,   etc   ; Fourier transform infrared spectroscopy; amines; antioxidants; biopharmaceuticals; carbon quantum dots; dissolved oxygen; electrochemiluminescence; metals;     Show all 9 Subjects
Abstract:
... Development of novel nanomaterial-based co-reactant is highly desired for enhancing ECL intensity and widespread analytical applications. Herein, we report the distinct role of amine-functionalized carbon quantum dots (f-CQDs) as a co-reactant, for the first time, augmenting the ECL property of Ru(bpy)₃²⁺ and demonstrating for biopharmaceutical (butein) detection. Unlike conventional co-reactants ...
DOI:
10.1007/s00216-019-02305-z

15. Production of verbascoside and its analogues in in vitro cultures of Verbascum thapsus L.

Author:
Temporiti, Marta Elisabetta Eleonora; Frezza, Claudio; Beccaccioli, Marzia; Gelardi, Luca; Bianco, Armandodoriano; Bonina, Francesco Paolo; Nielsen, Erik
Source:
Plant cell, tissue, and organ culture 2020 v.140 no.1 pp. 83-93
ISSN:
0167-6857
Subject:
phytochemicals,   etc   ; Verbascum thapsus; callus; culture media; cultured cells; explants; glycosides; leaf extracts; leaves; tissue culture; verbascoside;     Show all 11 Subjects
Abstract:
... In this work an effective method to start axenic cultures of Verbascum thapsus L. was developed. This allowed to obtain a high percentage of callus generation from leaf explants (around 70%) and to start the cultivation of suspension cultured cells rapidly growing in liquid culture medium. Moreover, the production in these materials of the phenylethanoid glycoside compound verbascoside was verifie ...
DOI:
10.1007/s11240-019-01712-5

16. Sesquiterpenes in grapes and wines: Occurrence, biosynthesis, functionality, and influence of winemaking processes

Author:
Li, Zizhan; Howell, Kate; Fang, Zhongxiang; Zhang, Pangzhen
Source:
Comprehensive reviews in food science and food safety 2020 v.19 no.1 pp. 247-281
ISSN:
1541-4337
Subject:
phytochemicals,   etc   ; biosynthesis; grapes; horticulture; odors; phenolic compounds; pyrazines; sesquiterpenoids; winemaking; wines;     Show all 10 Subjects
Abstract:
... Grapes are an important global horticultural product, and are mainly used for winemaking. Typically, grapes and wines are rich in various phytochemicals, including phenolics, terpenes, pyrazines, and benzenoids, with different compounds responsible for different nutritional and sensory properties. Among these compounds, sesquiterpenes, a subcategory of the terpenes, are attracting increasing inter ...
DOI:
10.1111/1541-4337.12516

17. Taxonomical and Phytochemical Characterisation of 10 <i>Stachys</i> Taxa Recorded in the Balkan Peninsula Flora: A Review

Author:
Bilušić Vundać, Vjera
Source:
Plants 2019 v.8 no.2
ISSN:
2223-7747
Subject:
phytochemicals,   etc   ; Betonica officinalis; Stachys; active ingredients; flora;     Show all 5 Subjects
Abstract:
... The genus Stachys is one of the largest genera of the Lamiaceae, and it comprises about 300 species. Some species are highly polymorphic, with a number of infraspecific taxa. The aim of the present review is to summarise the available knowledge on 10 taxa belonging to the Balkan Peninsula flora (S. alpina L., S. germanica L., S. menthifolia Vis., S. obliqua Waldst. Et Kit., S. officinalis (L.) Tre ...
DOI:
10.3390/plants8020032
PubMed:
30699897
PubMed Central:
PMC6409726

18. Exploring the multimodal role of phytochemicals in the modulation of cellular signaling pathways to combat age-related neurodegeneration

Author:
Uddin, Md. Sahab; Hossain, Md. Farhad; Mamun, Abdullah Al; Shah, Muhammad Ajmal; Hasana, Sharifa; Bulbul, Israt Jahan; Sarwar, Md. Shahid; Mansouri, Rasha A.; Ashraf, Ghulam Md; Rauf, Abdur; Abdel-Daim, Mohamed M.; Bin-Jumah, May N.
Source:
The Science of the total environment 2020 v.725 pp. 138313
ISSN:
0048-9697
Subject:
phytochemicals,   etc   ; Alzheimer disease; amyotrophic lateral sclerosis; apoptosis; inflammation; mitochondria; neurons; neuroprotective effect; oxidative stress; signal transduction; therapeutics;     Show all 11 Subjects
Abstract:
... Neurodegeneration is the progressive loss of neuronal structures and functions that lead to copious disorders like Alzheimer's (AD), Parkinson's (PD), Huntington's (HD), amyotrophic lateral sclerosis (ALS), and other less recurring diseases. Aging is the prime culprit for most neurodegenerative events. Moreover, the shared pathogenic factors of many neurodegenerative processes are inflammatory res ...
DOI:
10.1016/j.scitotenv.2020.138313

19. Combined treatment of epi-brassinolide and NaCl enhances the main phytochemicals in Chinese kale sprouts

Author:
Wang, Mengyu; Cai, Congxi; Lin, Jiayao; Tao, Han; Zeng, Wei; Zhang, Fen; Miao, Huiying; Sun, Bo; Wang, Qiaomei
Source:
Food chemistry 2020 v.315 pp. 126275
ISSN:
0308-8146
Subject:
phytochemicals,   etc   ; Brassica oleracea var. alboglabra; antioxidant activity; ascorbic acid; biosynthesis; carotenoids; functional foods; gene expression; glucosinolates; phenolic compounds; sodium chloride;     Show all 11 Subjects
Abstract:
... The effects of individual epi-brassinolide (eBL) and NaCl, as well as their combination on contents of main phytochemicals and antioxidant capacity of Chinese kale sprouts were investigated. Our results showed that the application of 100 nM eBL decreased the contents of individual and total glucosinolates, while treatments of 160 mM NaCl both alone and combined with 100 nM eBL enhanced the glucosi ...
DOI:
10.1016/j.foodchem.2020.126275

20. Plasmodium stage-selective antimalarials from Lophira lanceolata stem bark

Author:
Soré, Harouna; Lopatriello, Annalisa; Ebstie, Yehenew A.; Tenoh Guedoung, Alain R.; Hilou, Adama; Pereira, José A.; Kijjoa, Anake; Habluetzel, Annette; Taglialatela-Scafati, Orazio
Source:
Phytochemistry 2020 v.174 pp. 112336
ISSN:
0031-9422
Subject:
phytochemicals,   etc   ; Culicidae; Lophira lanceolata; Plasmodium; antimalarials; bark; glycosylation; humans; malaria; mass spectrometry; medicinal plants; moieties; nuclear magnetic resonance spectroscopy; parasites;     Show all 14 Subjects
Abstract:
... Targeting the transmissible stages of the Plasmodium parasite that develop in the human and mosquito host is a crucial strategy for malaria control and elimination. Medicinal plants offer a prolific source for the discovery of new antimalarial compounds. The recent identification of the gametocytocidal activity of lophirone E, obtained from the African plant Lophira lanceolata (Ochnaceae), inspire ...
DOI:
10.1016/j.phytochem.2020.112336