U.S. flag

An official website of the United States government

PubAg

Main content area

You searched for: Subject "pneumonia" Remove constraint Subject: "pneumonia"
Start Over

Search

4,211  Search Results

« Previous | 1 - 20 of 4,211 |
Number of results to display per page

Search Results

1. Comment on “Therapeutic target and molecular mechanism of vitamin C-treated pneumonia: a systematic study of network pharmacology” by R. Li, C. Guo, Y. Li, X. Liang, L. Yang and W. Huang, Food Funct., 2020, 11, 4765

Author:
Hemilä, Harri; Carr, Anitra
Source:
Food & function 2021 v.12 no.3 pp. 1371-1372
ISSN:
2042-650X
Subject:
pneumonia,   etc   ; pharmacology; therapeutics;     Show all 3 Subjects
Abstract:
... This Comment raises concerns about the article “Therapeutic target and molecular mechanism of vitamin C-treated pneumonia: a systematic study of network pharmacology”. ...
DOI:
10.1039/d0fo02189j

2. The Japanese 23-valent pneumococcal polysaccharide vaccine randomized clinical trial: Further reflections on the design and results

Author:
Cui, Yadong Adam; Folaranmi, Temitope; Buchwald, Ulrike Kirsten
Source:
Vaccine 2021 v.39 no.4 pp. 641-643
ISSN:
0264-410X
Subject:
pneumonia,   etc   ; Streptococcus pneumoniae; polysaccharides; vaccines;     Show all 4 Subjects
Abstract:
... The recent article by Gessner et al. discussed several concerns regarding the design and results of the clinical trial by Maruyama et al. in 2010 on the vaccine efficacy (VE) of 23-valent pneumococcal polysaccharide vaccine. First, Gessner et al. questioned the integrity of the study randomization and blinding. Maruyama et al. have indicated that study participants were individually randomized and ...
DOI:
10.1016/j.vaccine.2020.12.033

3. Invasive pulmonary aspergillosis associated with viral pneumonitis

Author:
Dewi, Intan MW; Janssen, Nico AF; Rosati, Diletta; Bruno, Mariolina; Netea, Mihai G; Brüggemann, Roger JM; Verweij, Paul E; van de Veerdonk, Frank L
Source:
Current opinion in microbiology 2021 v.62 pp. 21-27
ISSN:
1369-5274
Subject:
pneumonia,   etc   ; aspergillosis; fungi; immunotherapy; mortality; pathogenesis;     Show all 6 Subjects
Abstract:
... The occurrence of invasive pulmonary aspergillosis (IPA) in critically ill patients with viral pneumonitis has increasingly been reported in recent years. Influenza-associated pulmonary aspergillosis (IAPA) and COVID-19-associated pulmonary aspergillosis (CAPA) are the two most common forms of this fungal infection. These diseases cause high mortality in patients, most of whom were previously immu ...
DOI:
10.1016/j.mib.2021.04.006

4. Insights on chronic hypersensitivity pneumonitis' treatment: Factors associated with a favourable response to azathioprine

Author:
Raimundo, Sara; Pimenta, Ana Cláudia; Cruz-Martins, Natália; Rodrigues, Márcio Cunha; Melo, Natália; Mota, Patrícia Caetano; Sokhatska, Oksana; Bastos, Hélder Novais; Beltrão, Marília; Guimarães, Susana; Moura, Conceição Souto; Cunha, Rui; Pereira, José Miguel; Morais, António
Source:
Life sciences 2021 v.272 pp. 119274
ISSN:
0024-3205
Subject:
pneumonia,   etc   ; histology; hypersensitivity; immunosuppression; lungs; therapeutics;     Show all 6 Subjects
Abstract:
... The use of immunosuppressive and antifibrotic agents for the treatment of chronic hypersensitivity pneumonitis (CHP) appears promising, but there is still no evidence supporting the clinical decision regarding the implementation of each specific pharmacological strategy.Patients diagnosed with CHP and treated with azathioprine (AZA) were retrospectively selected from a single centre for Interstiti ...
DOI:
10.1016/j.lfs.2021.119274

5. Consolidated lung on contrast-enhanced chest CT: the use of spectral-detector computed tomography parameters in differentiating atelectasis and pneumonia

Author:
Konietzke, Philip; Steentoft, Hauke H.; Wagner, Willi L.; Albers, Jonas; Dullin, Christian; Skornitzke, Stephan; Stiller, Wolfram; Weber, Tim F.; Kauczor, Hans-Ulrich; Wielpütz, Mark O.
Source:
Heliyon 2021 v.7 no.5 pp. e07066
ISSN:
2405-8440
Subject:
pneumonia,   etc   ; chest; computed tomography; iodine; lungs;     Show all 5 Subjects
Abstract:
... To investigate the value of spectral-detector computed tomography (SDCT) parameters for the quantitative differentiation between atelectasis and pneumonia on contrast-enhanced chest CT.Sixty-three patients, 22 clinically diagnosed with pneumonia and 41 with atelectasis, underwent contrast-enhanced SDCT scans during the venous phase. CT numbers (Hounsfield Units [HU]) were measured on conventional ...
DOI:
10.1016/j.heliyon.2021.e07066

6. Research progress on coronavirus S proteins and their receptors

Author:
Yuan, Hao-Wen; Wen, Hong-Ling
Source:
Archives of virology 2021 v.166 no.7 pp. 1811-1817
ISSN:
0304-8608
Subject:
pneumonia,   etc   ; Orthocoronavirinae; cell membranes; humans; therapeutics; virology; viruses;     Show all 7 Subjects
Abstract:
... Coronaviruses are a large family of important pathogens that cause human and animal diseases. At the end of 2019, a pneumonia epidemic caused by a novel coronavirus brought attention to coronaviruses. Exploring the interaction between the virus and its receptor will be helpful in developing preventive vaccines and therapeutic drugs. The coronavirus spike protein (S) plays an important role in both ...
DOI:
10.1007/s00705-021-05008-y

7. PCV10 elicits Protein D IgG responses in Papua New Guinean children but has no impact on NTHi carriage in the first two years of life

Author:
Rahman, Tasmina; de Gier, Camilla; Orami, Tilda; Seppanen, Elke J.; Granland, Caitlyn M.; Francis, Jacinta P.; Michael, Audrey; Yoannes, Mition; Corscadden, Karli J.; Ford, Rebecca L.; Martinovich, Kelly M.; Jacoby, Peter; van den Biggelaar, Anita H.J.; Lehmann, Deborah; Richmond, Peter C.; Pomat, William S.; Thornton, Ruth B.; Kirkham, Lea-Ann S.
Source:
Vaccine 2021 v.39 no.26 pp. 3486-3492
ISSN:
0264-410X
Subject:
pneumonia,   etc   ; Haemophilus influenzae; Streptococcus pneumoniae; blood serum; vaccination; vaccines;     Show all 6 Subjects
Abstract:
... Nasopharyngeal colonisation with nontypeable Haemophilus influenzae (NTHi) is associated with development of infections including pneumonia and otitis media. The 10-valent pneumococcal conjugate vaccine (PCV10) uses NTHi Protein D (PD) as a carrier. Papua New Guinean children have exceptionally early and dense NTHi carriage, and high rates of NTHi-associated disease. Vaccination with PCV10 could p ...
DOI:
10.1016/j.vaccine.2021.05.022

8. Antibiotic resistance heterogeneity and LasR diversity within Pseudomonas aeruginosa populations from pneumonia in intensive care unit patients

Author:
Crémet, Lise; Leroy, Anne-Gaëlle; Muller, Damien; Delanou, Sandie; Burghelea, Alexandra; Broquet, Alexis; Roquilly, Antoine; Caroff, Nathalie
Source:
International journal of antimicrobial agents 2021 v.57 no.6 pp. 106341
ISSN:
0924-8579
Subject:
pneumonia,   etc   ; Pseudomonas aeruginosa; antibiotic resistance; ceftazidime; quorum sensing;     Show all 5 Subjects
Abstract:
... This study investigated within-host heterogeneity of 66 Pseudomonas aeruginosa populations from pneumonia in 51 critically ill ventilated patients by examining 30 colonies per bronchoalveolar lavage (BAL). Differences in antibiotic susceptibility and quorum-sensing (QS) phenotypes were observed between the members of 14 (21.2%) and 10 (15.2%) populations, respectively. A significant association wa ...
DOI:
10.1016/j.ijantimicag.2021.106341

9. Development and evaluation of a novel quenching probe PCR (GENECUBE) assay for rapidly detecting and distinguishing between Chlamydia pneumoniae and Chlamydia psittaci

Author:
Hisada, Kyoko; Hida, Yukio; Kawabata, Naoki; Kawashima, Yosuke; Soya, Yoshihiro; Shimada, Akihiro; Iwano, Masayuki; Kimura, Hideki
Source:
Journal of microbiological methods 2021 v.184 pp. 106212
ISSN:
0167-7012
Subject:
pneumonia,   etc   ; Chlamydophila pneumoniae; Chlamydophila psittaci; DNA; automation; cell culture; genes;     Show all 7 Subjects
Abstract:
... Early detection of the family Chlamydiaceae as pathogens is essential worldwide for the rapid and sufficient management of atypical pneumonia. GENECUBE (TOYOBO) is a novel fully automated gene analyzer capable of amplifying and detecting target DNAs within 50 min. In this study, we developed a new PCR assay with a specific quenching probe (PCR-QC assay) for rapidly distinguishing between Chlamydia ...
DOI:
10.1016/j.mimet.2021.106212

10. Activation of the Legionella pneumophila LegK7 Effector Kinase by the Host MOB1 Protein

Author:
Park, Sun Cheol; Cho, So Yeon; Kim, Tae Hee; Ko, Kyung Yeol; Song, Wan Seok; Kang, Seung Goo; Lee, Geun-Shik; Yoon, Sung-il
Source:
Journal of molecular biology 2021 v.433 no.3 pp. 166746
ISSN:
0022-2836
Subject:
pneumonia,   etc   ; Legionella pneumophila; cytoplasm; hydrophilicity; macrophages; molecular biology; pathogenesis; phosphorylation;     Show all 8 Subjects
Abstract:
... Legionella pneumophila infects alveolar macrophages and can cause life-threatening pneumonia in humans. Upon internalization into the host cell, L. pneumophila injects numerous effector proteins into the host cytoplasm as a part of its pathogenesis. LegK7 is an effector kinase of L. pneumophila that functionally mimics the eukaryotic Mst kinase and phosphorylates the host MOB1 protein to exploit t ...
DOI:
10.1016/j.jmb.2020.166746

11. Opsonization but not pretreatment of equine macrophages with hyperimmune plasma nonspecifically enhances phagocytosis and intracellular killing of Rhodococcus equi

Author:
Harvey, Aja B.; Bordin, Angela I.; Rocha, Joana N.; Bray, Jocelyn M.; Cohen, Noah D.
Source:
Journal of veterinary internal medicine 2021 v.35 no.1 pp. 590-596
ISSN:
0891-6640
Subject:
pneumonia,   etc   ; Rhodococcus equi; adults; macrophages; phagocytosis; veterinary medicine;     Show all 6 Subjects
Abstract:
... BACKGROUND: Evidence regarding the efficacy of equine hyperimmune plasma to prevent pneumonia in foals caused by Rhodococcus equi is limited and conflicting. HYPOTHESIS: Opsonization with R. equi‐specific hyperimmune plasma (HIP) will significantly increase phagocytosis and decrease intracellular replication of R. equi by alveolar macrophages (AMs) compared to normal plasma (NP). ANIMALS: Fifteen ...
DOI:
10.1111/jvim.16002

12. Recent progress in nanomaterial-based sensing of airborne viral and bacterial pathogens

Author:
Bhardwaj, Sanjeev K.; Bhardwaj, Neha; Kumar, Vanish; Bhatt, Deepanshu; Azzouz, Abdelmonaim; Bhaumik, Jayeeta; Kim, Ki-Hyun; Deep, Akash
Source:
Environment international 2021 v.146 pp. 106183
ISSN:
0160-4120
Subject:
pneumonia,   etc   ; anthrax; asthma; biosensors; botulism; common cold; environment; influenza; tuberculosis;     Show all 9 Subjects
Abstract:
... Airborne pathogens are small microbes that can cause a multitude of diseases (e.g., the common cold, flu, asthma, anthrax, tuberculosis, botulism, and pneumonia). As pathogens are transmitted from infected hosts via a number of routes (e.g., aerosolization, sneezing, and coughing), there is a great demand to accurately monitor their presence and behavior. Despite such need, conventional detection ...
DOI:
10.1016/j.envint.2020.106183

13. Methods for estimating the direct and indirect effect of 10 valent pneumococcal vaccine on nasopharyngeal carriage in children under 2 years in Matiari, Pakistan

Author:
Nisar, Muhammad Imran; Jehan, Fyezah; Shahid, Shahira; Shakoor, Sadia; Kabir, Furqan; Hotwani, Aneeta; Muneer, Sahrish; Ahmed, Sheraz; Whitney, Cynthia; Ali, Asad; Zaidi, Anita KM; Omer, Saad B; Iqbal, Najeeha
Source:
MethodsX 2021 v.8 pp. 101357
ISSN:
2215-0161
Subject:
pneumonia,   etc   ; Streptococcus pneumoniae; immunization; morbidity; mortality; vaccines; Pakistan;     Show all 7 Subjects
Abstract:
... Pneumonia is the leading cause of morbidity and mortality in children worldwide. The ten valent pneumococcal vaccine (PCV10) was introduced in Pakistan's Expanded Program on Immunization (EPI) in 2012 as a 3 + 0 schedule without catchup immunization. Nasopharyngeal carriage is taken as a surrogate marker to measure the impact of pneumococcal vaccine on populations. Carriage surveys are necessary t ...
DOI:
10.1016/j.mex.2021.101357

14. Laboratory indicators in COVID-19 and other pneumonias: Analysis for differential diagnosis and comparison of dynamic changes during 400-day follow-up

Author:
Wang, Jing; Zheng, Yufen; Chen, Yijun; Hu, Xingzhong; Peng, Minfei; Fang, Yicheng; Shen, Bo; Lu, Guoguang
Source:
Computational and Structural Biotechnology Journal 2021 v.19 pp. 2497-2507
ISSN:
2001-0370
Subject:
bacterial pneumonia; viral pneumonia,   etc   ; COVID-19 infection; biotechnology; eosinophils; high density lipoprotein cholesterol; low density lipoprotein cholesterol; models; nomogram; potassium; prealbumin; protein content; regression analysis;     Show all 13 Subjects
Abstract:
... COVID-19 is spreading rapidly all over the world, the patients' symptoms can be easily confused with other pneumonia types. Therefore, it is valuable to seek a laboratory differential diagnostic protocol of COVID-19 and other pneumonia types on admission, and to compare the dynamic changes in laboratory indicators during follow-up.A total of 143 COVID-19, 143 bacterial pneumonia and 145 convention ...
DOI:
10.1016/j.csbj.2021.04.063

15. Blood cultures and blood microbiota analysis as surrogates for bronchoalveolar lavage fluid analysis in dogs with bacterial pneumonia

Author:
Vientós-Plotts, A. I.; Ericsson, A. C.; Rindt, H.; Reinero, C. R.
Source:
BMC veterinary research 2021 v.17 no.1 pp. 129
ISSN:
1746-6148
Subject:
bacterial pneumonia,   etc   ; bacterial culture; blood; community structure; databases; dogs; inflammation; microbial communities; nucleotide sequences; veterinary medicine;     Show all 10 Subjects
Abstract:
... BACKGROUND: Diagnosis of canine bacterial pneumonia relies on airway lavage to confirm septic, suppurative inflammation, and a positive bacterial culture. Considering risks of bronchoalveolar lavage fluid (BALF) collection, minimally invasive methods like culture or next generation sequencing of blood would be appealing. In dogs with bacterial pneumonia, our study aims included (1): determining pr ...
DOI:
10.1186/s12917-021-02841-w

16. Comparison of antimicrobial prescription patterns in calves in Switzerland before and after the launch of online guidelines for prudent antimicrobial use

Author:
Hubbuch, Alina; Peter, Ruth; Willi, Barbara; Hartnack, Sonja; Müntener, Cedric; Naegeli, Hanspeter; Gerspach, Christian
Source:
BMC veterinary research 2021 v.17 no.1 pp. 2
ISSN:
1746-6148
Subject:
pneumonia,   etc   ; antibiotics; calves; confidence interval; diarrhea; fluoroquinolones; frequency; guidelines; hospitals; otitis; veterinary medicine; Switzerland;     Show all 12 Subjects
Abstract:
... BACKGROUND: The increasing threat of bacterial resistance promotes the need for antibiotic stewardship programs to foster responsible antimicrobial use. Therefore, guidelines for prudent use supported by an online stewardship tool (AntibioticScout.ch) were introduced in Switzerland in December 2016. They recommend (with decreasing preference) a first, second or third line antimicrobial for treatme ...
DOI:
10.1186/s12917-020-02704-w

17. Pneumonia scoring systems for severe COVID-19: which one is better

Author:
Cheng, PengFei; Wu, Hao; Yang, JunZhe; Song, XiaoYang; Xu, MengDa; Li, BiXi; Zhang, JunJun; Qin, MingZhe; Zhou, Cheng; Zhou, Xiang
Source:
Virology journal 2021 v.18 no.1 pp. 33
ISSN:
1743-422X
Subject:
pneumonia,   etc   ; COVID-19 infection; death; disease severity; mortality; risk; risk assessment; virology;     Show all 8 Subjects
Abstract:
... PURPOSE: To investigate the predictive significance of different pneumonia scoring systems in clinical severity and mortality risk of patients with severe novel coronavirus pneumonia. MATERIALS AND METHODS: A total of 53 cases of severe novel coronavirus pneumonia were confirmed. The APACHE II, MuLBSTA and CURB-65 scores of different treatment methods were calculated, and the predictive power of e ...
DOI:
10.1186/s12985-021-01502-6

18. Bioactivity, bioavailability, and gut microbiota transformations of dietary phenolic compounds: implications for COVID-19

Author:
Augusti, Paula R.; Conterato, Greicy M.M.; Denardin, Cristiane C.; Prazeres, Inês D.; Serra, Ana Teresa; Bronze, Maria R.; Emanuelli, Tatiana
Source:
The Journal of nutritional biochemistry 2021 v.97 pp. 108787
ISSN:
0955-2863
Subject:
pneumonia,   etc   ; COVID-19 infection; antioxidants; bioactive properties; bioavailability; biotransformation; digestion; disease prevention; intestinal microorganisms; therapeutics;     Show all 10 Subjects
Abstract:
... The outbreak of mysterious pneumonia at the end of 2019 is associated with widespread research interest worldwide. The coronavirus disease-19 (COVID-19) targets multiple organs through inflammatory, immune, and redox mechanisms, and no effective drug for its prophylaxis or treatment has been identified until now. The use of dietary bioactive compounds, such as phenolic compounds (PC), has emerged ...
DOI:
10.1016/j.jnutbio.2021.108787

19. Examining fine particulate matter and cause-specific morbidity during the 2017 North San Francisco Bay wildfires

Author:
Malig, Brian J.; Fairley, David; Pearson, Dharshani; Wu, Xiangmei; Ebisu, Keita; Basu, Rupa
Source:
The Science of the total environment 2021 v.787 pp. 147507
ISSN:
0048-9697
Subject:
pneumonia,   etc   ; asthma; diabetes; environment; morbidity; myocardial infarction; particulates; smoke; wildfires; California;     Show all 10 Subjects
Abstract:
... Recent increases in wildfire frequency and severity necessitate better understanding of health effects of wildfire smoke to protect affected populations.We examined relationships between fine particulate matter (PM₂.₅) and morbidity during wildfires in California, and whether those relationships differed during the fire compared to a similar non-fire period.For nine San Francisco Bay Area counties ...
DOI:
10.1016/j.scitotenv.2021.147507

20. Clinico-microbiological description and evaluation of rapid lateral flow immunoassay and PCR for detection of Burkholderia pseudomallei from patients hospitalized with sepsis and pneumonia: A twenty-one months study from Odisha, India

Author:
Radhakrishnan, Anjuna; Behera, Bijayini; Mishra, Baijayantimala; Mohapatra, Prasanta Raghab; Kumar, Rajesh; Singh, Arvind Kumar
Source:
Acta tropica 2021 v.221 pp. 105994
ISSN:
0001-706X
Subject:
pneumonia,   etc   ; Burkholderia pseudomallei; blood serum; early diagnosis; immunoassays; melioidosis; respiratory system; throat; urine; India;     Show all 10 Subjects
Abstract:
... Establishing a diagnosis of melioidosis based on clinical grounds is difficult in hospitalized patients with sepsis or community acquired pneumonia (CAP). We aimed to ascertain the prevalence, clinico-epidemiological and laboratory profile of melioidosis in hospitalized patients with sepsis or CAP, and to evaluate the diagnostic utility of rapid lateral flow immunoassay (LFI) and PCR in comparison ...
DOI:
10.1016/j.actatropica.2021.105994