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You searched for: Subject "prognosis" Remove constraint Subject: "prognosis"
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1. Environmental microcystin exposure triggers the poor prognosis of prostate cancer: Evidence from case-control, animal, and in vitro studies

Author:
Chun Pan; Haixiang Qin; Minghao Yan; Xuefeng Qiu; Wenyue Gong; Wenxin Luo; Hongqian Guo; Xiaodong Han
Source:
Journal of environmental sciences (China) 2023 v.127 pp. 69-81
ISSN:
1001-0742
Subject:
prognosis,   etc   ; blood serum; cadherins; estrogens; humans; lungs; metastasis; microcystin-LR; migratory behavior; odds ratio; prostatic neoplasms; risk; toxicity; vimentin; xenotransplantation; China;     Show all 16 Subjects
Abstract:
... Microcystin-leucine-arginine (MC-LR) is positively linked with multiple cancers in humans. However, the association between MC-LR and the risk and prognosis of prostate cancer has not been conducted in epidemiological studies. No reported studies have linked MC-LR exposure to the poor prognosis of prostate cancer by conducting experimental studies. The content of MC-LR was detected in most of the ...
DOI:
10.1016/j.jes.2022.05.051

2. A dual identification strategy based on padlock ligation and CRISPR/Cas14a for highly specific detection of BRAF V600E mutation in clinical samples

Author:
Weicheng Shi; Yao Gong; Decai Zhang; Tiantian Yang; Ming Yi; Jingyi Tan; Shijia Ding; Wei Cheng
Source:
Analytical methods 2022 v.14 no.19 pp. 1913-1921
ISSN:
1759-9679
Subject:
prognosis,   etc   ; biopsy; ligases; mutation;     Show all 4 Subjects
Abstract:
... BRAF V600E mutation is a single-nucleotide variation (SNV) that is widely found in various cancers and has been demonstrated to have a strong association with the prognosis and development of some diseases. Thus, we developed a strategy based on rolling circle amplification (RCA) and CRISPR/Cas14a to meet the great need for detecting highly specific BRAF V600E mutation in fine-needle biopsy sample ...
DOI:
10.1039/d2ay00319h

3. Circulating microRNAs as the Potential Diagnostic and Prognostic Biomarkers for Nasopharyngeal Carcinoma

Author:
Thuy Ai Huyen Le; Thuan Duc Lao
Source:
Genes 2022 v.13 no.7 pp. -
ISSN:
2073-4425
Subject:
prognosis,   etc   ; biomarkers; carcinoma; microRNA; nucleotides;     Show all 5 Subjects
Abstract:
... microRNAs are endogenous non-coding miRNAs, 19–25 nucleotides in length, that can be detected in the extracellular environment in stable forms, named circulating miRNAs (CIR-miRNAs). Since the first discovery of CIR-miRNAs, a large number of studies have demonstrated that the abnormal changes in its expression could be used to significantly distinguish nasopharyngeal carcinoma (NPC) from healthy c ...
DOI:
10.3390/genes13071160

4. Clinical and Genetic Characteristics of COL2A1-Associated Skeletal Dysplasias in 60 Russian Patients: Part I

Author:
Tatyana Markova; Vladimir Kenis; Evgeniy Melchenko; Darya Osipova; Tatyana Nagornova; Anna Orlova; Ekaterina Zakharova; Elena Dadali; Sergey Kutsev
Source:
Genes 2022 v.13 no.1 pp. -
ISSN:
2073-4425
Subject:
prognosis,   etc   ; childhood; genes; genetic analysis;     Show all 4 Subjects
Abstract:
... The significant variability in the clinical manifestations of COL2A1-associated skeletal dysplasias makes it necessary to conduct a clinical and genetic analysis of individual nosological variants, which will contribute to improving our understanding of the pathogenetic mechanisms and prognosis. We presented the clinical and genetic characteristics of 60 Russian pediatric patients with type II col ...
DOI:
10.3390/genes13010137

5. Metabolomics in the understanding and management of hepatic encephalopathy

Author:
Juliette Pelle; Florence A. Castelli; Marika Rudler; Imen Alioua; Benoit Colsch; François Fenaille; Christophe Junot; Dominique Thabut; Nicolas Weiss
Source:
Analytical biochemistry 2022 v.636 pp. 114477
ISSN:
0003-2697
Subject:
prognosis,   etc   ; biomarkers; encephalopathy; metabolomics; pathophysiology;     Show all 5 Subjects
Abstract:
... Metabolomics refers to the study of biological components below 1000 Daltons (Da) involved in metabolic pathways as substrates, products or effectors. According to the interconnected metabolic disturbances that have been described in the pathophysiology of hepatic encephalopathy (HE), this technique appears to be well adapted to study and better delineate the disease. This review will focus on rec ...
DOI:
10.1016/j.ab.2021.114477

6. Advances in preparation, mechanism and applications of various carbon materials in environmental applications: A review

Author:
P. Baraneedharan; Sethumathavan Vadivel; Anil C A; S. Beer Mohamed; Saravanan Rajendran
Source:
Chemosphere 2022 v.300 pp. 134596
ISSN:
0045-6535
Subject:
prognosis,   etc   ; carbon nanotubes; fullerene; graphene;     Show all 4 Subjects
Abstract:
... Carbon-related materials are now widely investigated in a various industrial field due to their excellent and unique qualities. It must be tailored to the application in such a way that it fits the application. At the same time, it needs to be generated in sufficient quantities for commercial use, and the synthesis method is the major sticking point here. Because most new materials are discovered ...
DOI:
10.1016/j.chemosphere.2022.134596

7. Circ_0000591 served as endogenous RNA for miR-326 to promote progression of cholangiocarcinoma via the TLR4/MyD88/IL6 axis

Author:
Fenqiang Xiao; Fei Xu; Hua Zhang; Xiaoming Shuai
Source:
Biochemical and biophysical research communications 2022 v.600 pp. 101-108
ISSN:
0006-291X
Subject:
prognosis,   etc   ; carcinogenesis; hepatoma; liver; research;     Show all 5 Subjects
Abstract:
... Cholangiocarcinoma (CCA) is the second most common liver malignancy with poor prognosis after hepatocellular carcinoma (HCC). Emerging evidences have proved that circular RNAs (circRNAs) are involved in the progression of multiple cancers, while their roles in tumorigenesis of CCA remains largely unclear. In the present study, we found circ_0000591 was upregulated in CCA cells and tissues. The hig ...
DOI:
10.1016/j.bbrc.2022.02.073

8. Dogs and cats with presumed or confirmed intracranial abscessation have low apparent diffusion coefficient values

Author:
Grégoire Scherf; James Sutherland‐Smith; Ane Uriarte
Source:
Veterinary radiology & ultrasound 2022 v.63 no.2 pp. 197-200
ISSN:
1058-8183
Subject:
prognosis,   etc   ; diffusivity; humans; radiology; ultrasonics;     Show all 5 Subjects
Abstract:
... Intracranial abscessation is a life‐threatening condition in dogs and cats, and rapid diagnosis is important for prognosis and treatment planning. The aims of this retrospective, single‐center, case series study were to describe clinical and MRI diffusion‐weighted imaging characteristics in three dogs and three cats with presumed or confirmed intracranial abscessation. All lesions appeared hyperin ...
DOI:
10.1111/vru.13064

9. Etiology, Clinical Presentation, and Outcome of Mandibular Fractures in Immature Dogs Treated with non-Invasive or Minimally Invasive Techniques

Author:
Ana C. Castejón-González; Darko Stefanovski; Alexander M. Reiter
Source:
Journal of veterinary dentistry 2022 v.39 no.1 pp. 78-88
ISSN:
2470-4083
Subject:
prognosis,   etc   ; dogs; malocclusion; pain; veterinary dentistry;     Show all 5 Subjects
Abstract:
... This study was performed to report etiology, clinical presentation, and outcome of mandibular fractures in immature dogs treated with non-invasive or minimally invasive techniques. Immature dogs diagnosed with mandibular fractures from 2001 to 2016 were included in this study. Diagnosis of the mandibular fracture was achieved by oral examination and diagnostic imaging in the anesthetized dog. Twen ...
DOI:
10.1177/08987564211072332

10. The Impact of Selenium Supplementation on Trauma Patients—Systematic Review and Meta-Analysis

Author:
Jen-Fu Huang; Chih-Po Hsu; Chun-Hsiang Ouyang; Chi-Tung Cheng; Chia-Cheng Wang; Chien-Hung Liao; Yu-Tung Wu; Chi-Hsun Hsieh
Source:
Nutrients 2022 v.14 no.2 pp. -
ISSN:
2072-6643
Subject:
prognosis,   etc   ; hospitals; meta-analysis; mortality; selenium;     Show all 5 Subjects
Abstract:
... This study aimed to assess current evidence regarding the effect of selenium (Se) supplementation on the prognosis in patients sustaining trauma. MEDLINE, Embase, and Web of Science databases were searched with the following terms: “trace element”, “selenium”, “copper”, “zinc”, “injury”, and “trauma”. Seven studies were included in the meta-analysis. The pooled results showed that Se supplementati ...
DOI:
10.3390/nu14020342

11. Epithelial‐to‐mesenchymal‐like transition events in melanoma

Author:
Dennis Pedri; Panagiotis Karras; Ewout Landeloos; Jean‐Christophe Marine; Florian Rambow
Source:
FEBS journal 2022 v.289 no.5 pp. 1352-1368
ISSN:
1742-464X
Subject:
prognosis,   etc   ; biomarkers; epithelium; melanoma; metastasis; phenotype; therapeutics;     Show all 7 Subjects
Abstract:
... Epithelial‐to‐mesenchymal transition (EMT), a process through which epithelial tumor cells acquire mesenchymal phenotypic properties, contributes to both metastatic dissemination and therapy resistance in cancer. Accumulating evidence indicates that nonepithelial tumors, including melanoma, can also gain mesenchymal‐like properties that increase their metastatic propensity and decrease their sensi ...
DOI:
10.1111/febs.16021

12. Performance of Different Echocardiographic Measurements of Left Atrial Size in Dogs by Observers with Different Levels of Experience

Author:
Alexander M. Safian; Giulio Menciotti; Sunshine M. Lahmers; Hyeon Jeong; Alessandra Franchini; Michele Borgarelli
Source:
Animals 2022 v.12 no.5 pp. -
ISSN:
2076-2615
Subject:
prognosis,   etc   ; body weight; echocardiography; risk assessment; veterinarians;     Show all 5 Subjects
Abstract:
... Assessment of left atrial (LA) sizes in dogs informs clinical staging, risk assessment, treatment decisions, and prognosis. The objective of this study was to assess the diagnostic performance of observers with different levels of experience measuring the LA with three different techniques. Echocardiographic images from 36 dogs with different degrees of left atrial enlargement (LAE) were retrospec ...
DOI:
10.3390/ani12050625

13. Prognostic value of selected one-, two- and three-dimensional and Doppler echocardiographic methods to assess severity in dogs with myxomatous mitral valve disease

Author:
A. Tidholm; J. Häggström
Source:
Journal of veterinary cardiology 2022 v.39 pp. 89-101
ISSN:
1760-2734
Subject:
prognosis,   etc   ; body weight; echocardiography; mortality; surface area;     Show all 5 Subjects
Abstract:
... Although challenging, predicting outcomes in dogs with myxomatous mitral valve disease (MMVD) is of importance to owners and veterinarians. Our aim was to compare the prognostic value of selected one-, two-, and three-dimensional and Doppler echocardiographic methods to predict cardiac-related and all-cause mortality in MMVD dogs. We hypothesize that three-dimensional methods would better predict ...
DOI:
10.1016/j.jvc.2021.12.005

14. Analysis of single extracellular vesicles for biomedical applications with especial emphasis on cancer investigations

Author:
Ting Wang; Yanlong Xing; Ziyi Cheng; Fabiao Yu
Source:
Trends in analytical chemistry 2022 v.152 pp. 116604
ISSN:
0165-9936
Subject:
prognosis,   etc   ; analytical chemistry; biomarkers; cell communication; lipids;     Show all 5 Subjects
Abstract:
... Extracellular vesicles (EVs) are lipid membrane enclosed nano-sized vesicles that are secreted by all known organisms. These vesicles are increasingly recognized as important circulating biomarkers for the diagnosis and prognosis of different diseases including various types of cancer, owing to their essential role in intercellular communication. EVs preserve heterogeneity in both physical propert ...
DOI:
10.1016/j.trac.2022.116604

15. Battery monitoring and prognostics optimization techniques: Challenges and opportunities

Author:
Concetta Semeraro; Mariateresa Caggiano; Abdul-Ghani Olabi; Michele Dassisti
Source:
Energy 2022 v.255 pp. 124538
ISSN:
0360-5442
Subject:
prognosis,   etc   ; batteries; electrochemistry; energy; nonlinear models; prediction;     Show all 6 Subjects
Abstract:
... In recent years, many researchers have been conducted on batteries' health monitoring and prognostics, mainly focusing on the batteries' state of charge (SOC). Accurately estimating the state of health (SOH) and predicting the remaining useful life (RUL) of battery components are very important for the prognosis and health management of the overall battery system. However, due to the non-linear dy ...
DOI:
10.1016/j.energy.2022.124538

16. Evaluation of staging systems to predict prognosis in hepatocellular carcinoma patients treated with radioembolization

Author:
Ece Meram; Colin Longhurst; Baran Umut Vardar; Kerim Karaoglu; Paul F. Laeseke; Orhan S. Ozkan
Source:
Heliyon 2022 v.8 no.1 pp. e08770
ISSN:
2405-8440
Subject:
prognosis,   etc   ; hepatoma; models; patients; regression analysis; China;     Show all 6 Subjects
Abstract:
... To compare the prognostic accuracy of nine staging systems, some of which are well-known and some of which have only been more recently described, for patients with unresectable HCC treated with radioembolization (RE). Individual scores or classes for the following staging systems were recorded or calculated for patients (n = 89) with unresectable HCC who underwent RE at a single tertiary care cen ...
DOI:
10.1016/j.heliyon.2022.e08770

17. A Nutrition and Inflammation-Related Nomogram to Predict Overall Survival in Surgically Resected Esophageal Squamous Cell Carcinoma (ESCC) Patients

Author:
Juan Li; Xinyu Mei; Di Sun; Mingfa Guo; Mingran Xie; Xia Chen
Source:
Nutrition and cancer 2022 v.74 no.5 pp. 1625-1635
ISSN:
1532-7914
Subject:
prognosis,   etc   ; biomarkers; models; nomogram; squamous cell carcinoma;     Show all 5 Subjects
Abstract:
... Pretreatment inflammation-based biomarkers and the prognostic nutrition index (PNI) have been used to evaluate prognosis in cancer patients. However, few studies have focused on the prognostic value of post-treatment inflammation-based biomarkers and PNI in ESCC patients. We aimed to investigate the values of pre/post-treatment inflammatory parameters and PNI for establishing a nomogram to predict ...
DOI:
10.1080/01635581.2021.1957131

18. An Iterative Method for Calculation of Wind Profiles at the Mesoscale and Microscale

Author:
Iwona Adamiec-Wójcik; Lucyna Brzozowska; Łukasz Drąg; Stanisław Wojciech
Source:
Boundary-layer meteorology 2022 v.183 no.3 pp. 423-445
ISSN:
0006-8314
Subject:
prognosis,   etc   ; algorithms; landscapes; meteorology; pollutants; thermodynamics; wind;     Show all 7 Subjects
Abstract:
... This paper presents the variational diagnostic model and iterative procedure, which enables the wind field in subdomains to be adjusted. Diagnostic models are not time dependent. Consideration of more complex features of the thermodynamic structure requires models with high resolution, which require large calculation times. The model presented applies the variational approach and enables topograph ...
DOI:
10.1007/s10546-022-00690-0

19. Identification of the Key miRNAs and Genes Associated with the Regulation of Non-Small Cell Lung Cancer: A Network-Based Approach

Author:
Zoya Shafat; Mohd Murshad Ahmed; Fahad N. Almajhdi; Tajamul Hussain; Shama Parveen; Anwar Ahmed
Source:
Genes 2022 v.13 no.7 pp. -
ISSN:
2073-4425
Subject:
prognosis,   etc   ; biomarkers; carcinogenesis; data collection; lung neoplasms; microRNA;     Show all 6 Subjects
Abstract:
... Lung cancer is the major cause of cancer-associated deaths across the world in both men and women. Lung cancer consists of two major clinicopathological categories, i.e., small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). Lack of diagnosis of NSCLC at an early stage in addition to poor prognosis results in ineffective treatment, thus, biomarkers for appropriate diagnosis and exa ...
DOI:
10.3390/genes13071174

20. Indications and outcome associated with positive‐pressure ventilation in dogs and cats: 127 cases

Author:
Laura A. Cagle; Kate Hopper; Steven E. Epstein
Source:
Journal of veterinary emergency and critical care 2022 v.32 no.3 pp. 365-375
ISSN:
1479-3261
Subject:
prognosis,   etc   ; blood gases; hospitals; patients; pneumonia; retrospective studies;     Show all 6 Subjects
Abstract:
... OBJECTIVES: To determine the indications and outcomes of positive‐pressure ventilation (PPV) and identify factors associated with successful weaning. DESIGN: Retrospective study from October 2009 to September 2013. SETTING: University teaching hospital. ANIMALS: One hundred and eleven dogs and 16 cats. MEASUREMENTS AND MAIN RESULTS: Medical records were retrospectively reviewed; signalment, indica ...
DOI:
10.1111/vec.13176