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1. Udder surgery in ewes

Author:
Tsioli, V.; Fthenakis, G.C.
Source:
Small ruminant research 2019 v.181 pp. 76-84
ISSN:
0921-4488
Subject:
prognosis,   etc   ; ewes; surgery; udders;     Show all 4 Subjects
Abstract:
... Objective of this review is to present relevant information about udder surgery in ewes and to discuss its applications within the frame of sheep health management. The indications, diagnostic procedures, techniques, possible complications, post-operative care and prognosis of surgical conditions of the ovine udder are reviewed. Mammary surgery may help in decision-taking for the management of var ...
DOI:
10.1016/j.smallrumres.2019.06.019

2. Assessment of left ventricular function in horses with aortic regurgitation by 2D speckle tracking

Author:
Decloedt, A.; Ven, S.; De Clercq, D.; Rademakers, F.; van Loon, G.
Source:
BMC veterinary research 2020 v.16 no.1 pp. 93
ISSN:
1746-6148
Subject:
prognosis,   etc   ; arrhythmia; deformation; heart failure; heart valve diseases; horses;     Show all 6 Subjects
Abstract:
... BACKGROUND: Aortic regurgitation (AR) may lead to left ventricular (LV) dilatation, cardiac arrhythmias and heart failure. Close follow-up of horses with AR is therefore paramount to detect onset of cardiac decompensation. The aim of this study was to examine whether two-dimensional speckle tracking (2DST) can be used to detect altered myocardial function in horses with chronic AR compared to cont ...
DOI:
10.1186/s12917-020-02307-5
PubMed:
32197611
PubMed Central:
PMC7085189

3. Aptamer-based nanostructured interfaces for the detection and release of circulating tumor cells

Author:
Ding, Pi; Wang, Zhili; Wu, Zeen; Zhu, Weipei; Liu, Lifen; Sun, Na; Pei, Renjun
Source:
Journal of materials chemistry B 2020 v.8 no.16 pp. 3408-3422
ISSN:
2050-7518
Subject:
prognosis,   etc   ; blood; immunogenicity; monitoring; neoplasm cells; neoplasms; oligonucleotides; patients; therapeutics;     Show all 9 Subjects
Abstract:
... Analysis of circulating tumor cells (CTCs) can provide significant clinical information for tumors, which has proven to be helpful for cancer diagnosis, prognosis monitoring, treatment efficacy, and personalized therapy. However, CTCs are an extremely rare cell population, which challenges the isolation of CTCs from patient blood. Over the last few decades, many strategies for CTC detection have b ...
DOI:
10.1039/c9tb02457c

4. Nanoparticles-mediated reoxygenation strategy relieves tumor hypoxia for enhanced cancer therapy

Author:
Wang, Hong; Li, Jie; Wang, Yuqi; Gong, Xiang; Xu, Xiaoxuan; Wang, Jiaoying; Li, Yaping; Sha, Xianyi; Zhang, Zhiwen
Source:
Journal of controlled release 2020 v.319 pp. 25-45
ISSN:
0168-3659
Subject:
prognosis,   etc   ; cancer therapy; hypoxia; immunotherapy; nanoparticles; neoplasms; oxygen; photochemotherapy; radiotherapy;     Show all 9 Subjects
Abstract:
... Tumor hypoxia is a characteristic hallmark of malignant solid tumors, which remains an essential impediment to many current treatments like chemotherapy, radiotherapy, photodynamic therapy and immunotherapy, thereby leading to poor clinical prognosis after therapy. Rationally, modulating tumor hypoxia can be of great interest to augment the therapeutic efficacy of these treatments. In this review, ...
DOI:
10.1016/j.jconrel.2019.12.028

5. Detection of Circulating Tumor-Related Materials by Aptamer Capturing and Endogenous Enzyme-Signal Amplification

Author:
Shen, Luyao; Jia, Keke; Bing, Tao; Zhang, Zhibao; Zhen, Xiaoxiao; Liu, Xiangjun; Zhang, Nan; Shangguan, Dihua
Source:
Analytical chemistry 2020 v.92 no.7 pp. 5370-5378
ISSN:
1520-6882
Subject:
prognosis,   etc   ; alkaline phosphatase; colorectal neoplasms; colorimetry; magnetism; metastasis; oligonucleotides; patients;     Show all 8 Subjects
Abstract:
... Circulating tumor-related materials (CTRMs) shed from original or metastatic tumors, carry a lot of tumor information and are considered as important markers for cancer diagnosis and metastasis prognosis. Herein, we report a colorimetric detection strategy for CTRMs based on aptamer-based magnetic isolation and endogenous alkaline phosphatase (AP)-signal amplification. This strategy exhibited high ...
DOI:
10.1021/acs.analchem.0c00051

6. Identification of prognostic signatures associated with long-term overall survival of thyroid cancer patients based on a competing endogenous RNA network

Author:
Li, Xiaoping; Dai, Dayou; Wang, Heyuan; Wu, Bing; Wang, Rui
Source:
Genomics 2020 v.112 no.2 pp. 1197-1207
ISSN:
0888-7543
Subject:
prognosis,   etc   ; databases; microRNA; patients; prediction; risk; thyroid neoplasms;     Show all 7 Subjects
Abstract:
... Competing endogenous RNAs (ceRNAs) are considered as transcripts that can regulate each other at post-transcription level by competing for shared miRNAs. Considering the key roles of lncRNAs acting as ceRNAs in progression of solid tumors, to develop prognostic signatures in thyroid cancer (THCA), patients with corresponding clinical data were selected and two ceRNA networks were constructed using ...
DOI:
10.1016/j.ygeno.2019.07.005

7. Management of Primary Injuries of the Medial Collateral Ligament of the Carpus in Two Horses

Author:
Quiney, Laura; Murray, Rachel; Dyson, Sue
Source:
Journal of equine veterinary science 2020 v.86 pp. 102878
ISSN:
0737-0806
Subject:
prognosis,   etc   ; carpus; case studies; horses; lameness; ligaments; therapeutics;     Show all 7 Subjects
Abstract:
... This case report describes the successful management of two horses with medial carpal collateral ligament injury. This is a rare cause of forelimb lameness and existing reports indicate a poor prognosis for return to athletic function with conservative management. Both horses were treated with a combination of box rest with controlled exercise and high-intensity laser therapy (HILT). Both horses r ...
DOI:
10.1016/j.jevs.2019.102878

8. Structural health monitoring of grouted connections for offshore wind turbines by means of acoustic emission: An experimental study

Author:
Tziavos, Nikolaos I.; Hemida, H.; Dirar, S.; Papaelias, M.; Metje, N.; Baniotopoulos, C.
Source:
Renewable energy 2020 v.147 pp. 130-140
ISSN:
0960-1481
Subject:
prognosis,   etc   ; acoustics; cracking; monitoring; renewable energy sources; steel; wind turbines;     Show all 7 Subjects
Abstract:
... Grouted connections for offshore wind turbines are formed by attaching overlapping steel piles with an ultra-high strength cementitious grout. The structural performance of grouted connections is critical for the substructures in order to exhibit sufficient resistance to environmental loads. The long-term integrity of the grout core can be compromised due to the complex stress states present, lead ...
DOI:
10.1016/j.renene.2019.08.114

9. Grade-specific diagnostic and prognostic biomarkers in breast cancer

Author:
Jayanthi, V.S.P.K. Sankara Aditya; Das, Asim Bikas; Saxena, Urmila
Source:
Genomics 2020 v.112 no.1 pp. 388-396
ISSN:
0888-7543
Subject:
prognosis,   etc   ; biomarkers; breast neoplasms; genes; metastasis; patients; phenotype;     Show all 7 Subjects
Abstract:
... An integrative approach is presented to identify grade-specific biomarkers for breast cancer. Grade-specific molecular interaction networks were constructed with differentially expressed genes (DEGs) of cancer grade 1, 2, and 3. We observed that the molecular network of grade3 is predominantly associated with cancer-specific processes. Among the top ten connected DEGs in the grade3, the increase i ...
DOI:
10.1016/j.ygeno.2019.03.001

10. Correction to: Myiasis in humans—a global case report evaluation and literature analysis

Author:
Bernhardt, Victoria; Finkelmeier, Fabian; Verhoff, Marcel A.; Amendt, Jens
Source:
Parasitology research 2019 v.118 no.2 pp. 723
ISSN:
0932-0113
Subject:
prognosis,   etc   ; case studies; humans; myiasis;     Show all 4 Subjects
Abstract:
... It was brought to the authors’ attention that a citation within the published article was cited incorrectly. ...
DOI:
10.1007/s00436-018-6187-x

11. Microfluidic systems for cancer diagnostics

Author:
Garcia-Cordero, Jose L; Maerkl, Sebastian J
Source:
Current opinion in biotechnology 2020 v.65 pp. 37-44
ISSN:
0958-1669
Subject:
prognosis,   etc   ; DNA; biomarkers; biopsy; biosensors; blood serum; diagnostic techniques; exosomes; neoplasm cells; neoplasms; proteins;     Show all 11 Subjects
Abstract:
... Although not employed in the clinic as of yet, microfluidic systems are likely to become a key technology for cancer diagnostics and prognosis. Microfluidic devices have been developed for the analysis of various biomarkers including circulating tumor cells, cell-free DNA, exosomes, and proteins, primarily in liquid biopsies such as serum, plasma, and whole blood, avoiding the need for tumor tissu ...
DOI:
10.1016/j.copbio.2019.11.022

12. Nuclear factor erythroid 2 (NF-E2)-related factor 2 (Nrf2) in non-small cell lung cancer

Author:
Zeng, Zhi; Wang, Zi-yao; Li, Yu-kun; Ye, Dong-mei; Zeng, Juan; Hu, Jia-li; Chen, Pi-feng; Xiao, Jiao; Zou, Juan; Li, Zhen-hua
Source:
Life sciences 2020 v.254 pp. 117325
ISSN:
0024-3205
Subject:
prognosis,   etc   ; carcinogenesis; chemical structure; drug therapy; gene expression; lung neoplasms; transcription factors;     Show all 7 Subjects
Abstract:
... Nuclear factor erythroid 2 (NF-E2)-related factor 2 (Nrf2) is a transcription factor that can regulate downstream target gene expression. Kelch-like ECH-associated protein 1 (Keap1) negatively regulates Nrf2 activation and translocation to target its 26S proteasomal degradation. It has been widely reported that the Keap1/Nrf2 pathway is associated with tumorigenesis, chemotherapy resistance and pr ...
DOI:
10.1016/j.lfs.2020.117325

13. A superstable homogeneous lipiodol-ICG formulation for locoregional hepatocellular carcinoma treatment

Author:
Chen, Hu; Cheng, Hongwei; Dai, Qixuan; Cheng, Yi; Zhang, Yang; Li, Dengfeng; Sun, Yang; Mao, Jingsong; Ren, Ke; Chu, Chengchao; Liu, Gang
Source:
Journal of controlled release 2020 v.323 pp. 635-643
ISSN:
0168-3659
Subject:
prognosis,   etc   ; computed tomography; fluorescence; hepatoma; models; patients; rabbits; resection; solvents; viscosity;     Show all 10 Subjects
Abstract:
... Accurate identification of surgical margins for malignancy remains a challenge in the surgical therapy of cancer, and this encountered interoperative difficulties which directly contribute to the prognosis of patients. In recent years, indocyanine green (ICG) has been approved and applied in clinical settings for lesions detection, especially for the precise surgical resection. However, rapid clea ...
DOI:
10.1016/j.jconrel.2020.04.021

14. Measurement of the concentration of serum soluble interleukin-2 receptor alpha chain in dogs with lymphoma

Author:
Mizutani, Noriyuki; Goto-Koshino, Yuko; Kurata, Keigo; Fujiwara-Igarashi, Aki; Sakaguchi, Masahiro; Asada, Minoru; Ohno, Koichi; Tsujimoto, Hajime
Source:
Veterinary immunology and immunopathology 2020 v.225 pp. 110054
ISSN:
0165-2427
Subject:
prognosis,   etc   ; B-cell lymphoma; blood serum; dogs; humans; interleukin-2; lymph nodes; lymphocytes; precipitin tests; therapeutics;     Show all 10 Subjects
Abstract:
... Soluble interleukin-2 receptor (sIL-2r) is released directly from the surface of lymphocytes expressing interleukin-2 receptor alpha chain (CD25), and its serum concentration has been found to reflect the prognosis of human lymphoproliferative malignancies. In this study, we demonstrated the presence of sIL-2r in canine serum and developed a specific sandwich enzyme-linked immunosorbent assay (ELI ...
DOI:
10.1016/j.vetimm.2020.110054

15. Clinically Applicable AI System for Accurate Diagnosis, Quantitative Measurements, and Prognosis of COVID-19 Pneumonia Using Computed Tomography

Author:
Zhang, Kang; Liu, Xiaohong; Shen, Jun; Li, Zhihuan; Sang, Ye; Wu, Xingwang; Zha, Yunfei; Liang, Wenhua; Wang, Chengdi; Wang, Ke; Ye, Linsen; Gao, Ming; Zhou, Zhongguo; Li, Liang; Wang, Jin; Yang, Zehong; Cai, Huimin; Xu, Jie; Yang, Lei; Cai, Wenjia; Xu, Wenqin; Wu, Shaoxu; Zhang, Wei; Jiang, Shanping; Zheng, Lianghong; Zhang, Xuan; Wang, Li; Lu, Liu; Li, Jiaming; Yin, Haiping; Wang, Winston; Li, Oulan; Zhang, Charlotte; Liang, Liang; Wu, Tao; Deng, Ruiyun; Wei, Kang; Zhou, Yong; Chen, Ting; Lau, Johnson Yiu-Nam; Fok, Manson; He, Jianxing; Lin, Tianxin; Li, Weimin; Wang, Guangyu
Source:
Cell 2020 v.181 no.6 pp. 1423-1433.e11
ISSN:
0092-8674
Subject:
prognosis,   etc   ; Coronavirinae; Coronavirus infections; computed tomography; databases; patients; pneumonia; quantitative analysis; viruses;     Show all 9 Subjects
Abstract:
... Many COVID-19 patients infected by SARS-CoV-2 virus develop pneumonia (called novel coronavirus pneumonia, NCP) and rapidly progress to respiratory failure. However, rapid diagnosis and identification of high-risk patients for early intervention are challenging. Using a large computed tomography (CT) database from 3,777 patients, we developed an AI system that can diagnose NCP and differentiate it ...
DOI:
10.1016/j.cell.2020.04.045

16. Assessment of body water distribution in patients with sepsis during fluid resuscitation using multi-frequency direct segmental bioelectrical impedance analysis

Author:
Park, Inwon; Lee, Jae Hyuk; Jang, Dong-Hyun; Kim, Joonghee; Hwang, Bo Rah; Kim, Seoyoung; Lee, Ji Eun; Jo, You Hwan
Source:
Clinical nutrition 2020 v.39 no.6 pp. 1826-1831
ISSN:
0261-5614
Subject:
prognosis,   etc   ; adults; bioelectrical impedance; body water; body weight; edema; patients; prospective studies; sepsis (infection); water distribution;     Show all 10 Subjects
Abstract:
... Although initial fluid resuscitation in sepsis is critical for the treatment of tissue hypoperfusion, little evidence supports the distribution of infused fluid in patients with sepsis. This study was designed to assess the body water distribution in patients with sepsis using bioelectrical impedance analysis and correlate the trend in body water distribution during fluid treatment with the progno ...
DOI:
10.1016/j.clnu.2019.07.022

17. Muscle weakness: Understanding the principles of myopathy and neuropathy in the critically ill patient and the management options

Author:
García-Martínez, Miguel Ángel; Montejo González, Juan Carlos; García-de-Lorenzo y Mateos, Abelardo; Teijeira, Susana
Source:
Clinical nutrition 2020 v.39 no.5 pp. 1331-1344
ISSN:
0261-5614
Subject:
prognosis,   etc   ; hospitals; morbidity; mortality; muscles; muscular diseases; pathophysiology; patients; peripheral nervous system diseases;     Show all 9 Subjects
Abstract:
... Myo-neuropathy of the critically ill patient is a difficult nosological entity to understand and manage. It appears soon after injury, and it is estimated that 20–30% of patients admitted to Intensive Care Units will develop it in some degree. Although muscular and nervous involvement are related, the former has a better prognosis. Myo-neuropathy associates to more morbidity, longer stay in Intens ...
DOI:
10.1016/j.clnu.2019.05.027

18. Nutritional status and all-cause mortality in older adults with acute coronary syndrome

Author:
Tonet, Elisabetta; Campo, Gianluca; Maietti, Elisa; Formiga, Francesc; Martinez-Sellés, Manuel; Pavasini, Rita; Biscaglia, Simone; Serenelli, Matteo; Sanchis, Juan; Diez-Villanueva, Pablo; Bugani, Giulia; Vitali, Francesco; Ruggiero, Rossella; Cimaglia, Paolo; Bernucci, Davide; Volpato, Stefano; Ferrari, Roberto; Ariza-Solé, Albert
Source:
Clinical nutrition 2020 v.39 no.5 pp. 1572-1579
ISSN:
0261-5614
Subject:
prognosis,   etc   ; death; elderly; exercise test; immunologic factors; malnutrition; mortality; nutritional status; patients; physical activity;     Show all 10 Subjects
Abstract:
... The present analysis investigated the prevalence and the prognostic implication of nutritional status in older adults hospitalized for acute coronary syndrome (ACS).The analysis is based on older ACS patients included in the FRASER and LONGEVO SCA studies. The Global Risk of Acute Coronary Events (GRACE) risk score was computed in all patients. Nutritional status was assessed with the Mini Nutriti ...
DOI:
10.1016/j.clnu.2019.06.025

19. Luminescence approaches for the rapid detection of disease-related receptor proteins using transition metal-based probes

Author:
Ma, Dik-Lung; Wu, Chun; Liu, Hao; Wu, Ke-Jia; Leung, Chung-Hang
Source:
Journal of materials chemistry B 2020 v.8 no.16 pp. 3249-3260
ISSN:
2050-7518
Subject:
prognosis,   etc   ; biomarkers; human diseases; luminescence; metals; monitoring; prediction; proteins; rapid methods;     Show all 9 Subjects
Abstract:
... Protein biomarkers, particularly abnormally expressed receptor proteins, have been proved to be one of the crucial biomarkers for the rapid assessment, diagnosis, prognosis and prediction of specific human diseases. Transition metal based strategies in particular possess delightful strengths in the in-field and real-time visualization of receptor proteins owing to their unique photophysical proper ...
DOI:
10.1039/c9tb01889a

20. The GLIM criteria for defining malnutrition can predict physical function and prognosis in patients with cardiovascular disease

Author:
Kootaka, Yoshifumi; Kamiya, Kentaro; Hamazaki, Nobuaki; Nozaki, Kohei; Ichikawa, Takafumi; Nakamura, Takeshi; Yamashita, Masashi; Maekawa, Emi; Reed, Jennifer L.; Yamaoka-Tojo, Minako; Matsunaga, Atsuhiko; Ako, Junya
Source:
Clinical nutrition 2020
ISSN:
0261-5614
Subject:
prognosis,   etc   ; clinical nutrition; heart failure; hospitals; leadership; malnutrition; men; metabolism; mortality; patients; risk assessment; walking;     Show all 12 Subjects
Abstract:
... The Global Leadership Initiative on Malnutrition (GLIM) published a new international standard for defining malnutrition in 2018. The GLIM criteria were compared with the European Society for Clinical Nutrition and Metabolism (ESPEN) criteria in relation to physical function and mortality risk in patients with cardiovascular disease (CVD).A total of 921 CVD patients ≥ 20 years old (67.8 ± 13.4 yea ...
DOI:
10.1016/j.clnu.2020.04.038