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1. Comparison of two azobenzene-based amino acid derivatization reagents for LC-MS/MS analysis in positive and negative ESI modes

Author:
Ernesto de Jesus Zapata Flores; Nguyễn Kim Ngân Bùi; Sigrid Selberg; Koit Herodes; Ivo Leito
Source:
Talanta 2023 v.252 pp. 123803
ISSN:
0039-9140
Subject:
proline,   etc   ; derivatization; fermentation; fermented beverages; ionization; Eastern European region;     Show all 6 Subjects
Abstract:
... Derivatization reagents based on azobenzene containing different N-hydroxysuccinimidyl moieties– AzoB (carbamate) and AzoC (ester) – are proposed for the LC-ESI-MS analysis of free amino acids in fermented beverages and juices. A dual comparison between LC-MS/MS in positive and negative ESI modes in dynamic Multiple Reaction Monitoring (dMRM) and Neutral Loss Scan was investigated. The results ind ...
DOI:
10.1016/j.talanta.2022.123803

2. SlNPR1 modulates chilling stress resistance in tomato plant by alleviating oxidative damage and affecting the synthesis of ferulic acid

Author:
Pan Shu; Yujing Li; Lanting Xiang; Jiping Sheng; Lin Shen
Source:
Scientia horticulturae 2023 v.307 pp. 111486
ISSN:
0304-4238
Subject:
proline,   etc   ; CRISPR-Cas systems; antioxidant enzymes; ferulic acid; hydrogen peroxide; mutagenesis; protein content; stress tolerance; superoxide anion; temperature; tomatoes; transcription factors;     Show all 12 Subjects
Abstract:
... Non-expresser of pathogenesis-related genes 1 (NPR1) has been demonstrated to be a master transcription factor during resistance against pathogens, the mechanisms by which regulates chilling stress, however, remain unclear. Our results revealed that the expression and protein content of SlNPR1 were dramatically induced by low temperature (4 °C). CRISPR/Cas9-mediated SlNPR1 mutagenesis aggravated t ...
DOI:
10.1016/j.scienta.2022.111486

3. Morphological, physiological, biochemical, and transcriptome studies reveal the importance of transporters and stress signaling pathways during salinity stress in Prunus

Author:
Acharya Biswa R.; Sandhu Devinder; Dueñas Christian; Dueñas Marco; Pudussery Manju V.; Kaundal Amita; Ferreira Jorge F.S.; Suarez Donald L.; Skaggs Todd H.
Source:
Scientific reports 2022 v.12 no.1 pp. 1274
ISSN:
2045-2322
Subject:
proline,   etc   ; Prunus; almonds; chlorides; economic feasibility; electrical conductivity; gene expression regulation; genotype; ion channels; salinity; salt stress; salt tolerance; sequence analysis; transcriptome;     Show all 14 Subjects
Abstract:
... The almond crop has high economic importance on a global scale, but its sensitivity to salinity stress can cause severe yield losses. Salt-tolerant rootstocks are vital for crop economic feasibility under saline conditions. Two commercial rootstocks submitted to salinity, and evaluated through different parameters, had contrasting results with the survival rates of 90.6% for 'Rootpac 40' (tolerant ...
Handle:
10113/7709627
DOI:
10.1038/s41598-022-05202-1

4. Olfaction and gustatory senses promote feeding through different pathways in yellowtail, Seriola quinqueradiata

Author:
Ayaka Senzui; Haruhisa Fukada
Source:
Aquaculture 2023 v.562 pp. 738814
ISSN:
0044-8486
Subject:
proline,   etc   ; Seriola quinqueradiata; alanine; appetite; aquaculture; carnivores; cerebellum; feed intake; fish; fish meal; food intake; gene expression; hypothalamus; neuropeptide Y; odors; olfactory bulb; plant proteins; smell; taste;     Show all 19 Subjects
Abstract:
... For sustainable aquaculture, the replacement of dietary fishmeal with plant protein is becoming more common because fishmeal resources are limited. However, in the case of carnivorous fish such as yellowtail (Seriola quinqueradiata), reducing the dietary fishmeal level often causes low feed intake. Improving feed intake is important in the use of a non- and low-fishmeal diet. However, little is kn ...
DOI:
10.1016/j.aquaculture.2022.738814

5. Evaluating drought stress tolerance in different Camellia sinensis L. cultivars and effect of melatonin on strengthening antioxidant system

Author:
Iman Khesali Langaroudi; Saeed Piri; Sanam Safaei Chaeikar; Behrooz Salehi
Source:
Scientia horticulturae 2023 v.307 pp. 111517
ISSN:
0304-4238
Subject:
proline,   etc   ; Camellia sinensis; antioxidants; carotenoids; catalase; chlorophyll; cultivars; drought tolerance; foliar application; growth and development; irrigation rates; malondialdehyde; melatonin; peroxidase; polyphenols; protein content; sugars; tea; water stress; Iran;     Show all 20 Subjects
Abstract:
... Drought stress really restring the growth and development of tea plant and affecting quality and yield. In tea growing areas of Iran, drought stress is a serious problem that affects the yield and quality of green leaves, therefore introducing cultivars that tolerate drought stress is one of the breeding purpose. To distinguish the variations in four tea cultivars response to drought stress and th ...
DOI:
10.1016/j.scienta.2022.111517

6. The older, the better: Ageing improves the efficiency of biochar-compost mixture to alleviate drought stress in plant and soil

Author:
Charlotte Védère; Manhattan Lebrun; Philippe Biron; Séverine Planchais; Marianne Bordenave-Jacquemin; Nicolas Honvault; Stéphane Firmin; Arnould Savouré; David Houben; Cornelia Rumpel
Source:
Science of the total environment 2023 v.856 pp. 158920
ISSN:
0048-9697
Subject:
proline,   etc   ; belowground biomass; biochar; biomass production; climate change; composts; drought; environment; gas exchange; leaves; plant growth; soil; soil enzymes; stomatal conductance; water shortages; water stress; water use efficiency;     Show all 17 Subjects
Abstract:
... Due to increased drought frequency following climate change, practices improving water use efficiency and reducing water-stress are needed. The efficiency of organic amendments to improve plant growth conditions under drought is poorly known. Our aim was to investigate if organic amendments can attenuate plant water-stress due to their effect on the plant-soil system and if this effect may increas ...
DOI:
10.1016/j.scitotenv.2022.158920

7. Elevated level of chilling tolerance in cucumber fruit was obtained by β-aminobutyric acid via the regulation of antioxidative response and metabolism of energy, proline and unsaturated fatty acid

Author:
Bing Wang; Hua Zhang; Yubao Li; Yonghua Zheng; Lei Wang
Source:
Scientia horticulturae 2023 v.307 pp. 111521
ISSN:
0304-4238
Subject:
proline,   etc   ; antioxidant activity; catalase; cold storage; cucumbers; cytochrome-c oxidase; energy; enzyme activity; fatty acid composition; fruits; gene expression; hydrogen peroxide; metabolism; succinate dehydrogenase (quinone); superoxide anion; superoxide dismutase; unsaturated fatty acids;     Show all 17 Subjects
Abstract:
... This experimental study was conducted to investigate the effects of β-aminobutyric acid (BABA) on chilling injury in cold-stored cucumber fruit. Results showed that BABA decreased the development of chilling injury in cucumber fruit. BABA-treated fruit exhibited elevated antioxidant ability, indicated by high activities of superoxide dismutase (SOD) and catalase (CAT) and low levels of hydrogen pe ...
DOI:
10.1016/j.scienta.2022.111521

8. Physio-biochemical responses of grafted tomatoes differing in thermotolerance to heat stress and recovery

Author:
Chungkeun Lee; Joshua T. Harvey; Kuan Qin; Daniel I. Leskovar
Source:
Scientia horticulturae 2023 v.308 pp. 111546
ISSN:
0304-4238
Subject:
proline,   etc   ; Solanum lycopersicum; antioxidant enzymes; ascorbate peroxidase; carotenoids; catalase; chlorophyll; cultivars; electrolyte leakage; glutathione-disulfide reductase; heat; heat stress; heat tolerance; heat treatment; leaves; malondialdehyde; peroxidase; rootstocks; superoxide dismutase; tomatoes; vegetative growth;     Show all 21 Subjects
Abstract:
... The aim of this study was to evaluate the physiological and biochemical heat responses of grafted tomato (Solanum lycopersicum L.) seedlings and their changes during the post-stress recovery period. Heat-tolerant ‘Celebrity’ and heat-sensitive ‘Arkansas Traveler’ tomatoes were grafted onto a commercial ‘Maxifort’ rootstock, and transplants were grown in growth chambers for 14 days of heat treatmen ...
DOI:
10.1016/j.scienta.2022.111546

9. The effect of nitrite and nitrate treatment on growth performance, nutritional composition and flavor-associated metabolites of grass carp (Ctenopharyngodon idella)

Author:
Jun-Ming Zhang; Bing Fu; Yi-chao Li; Jin-Hui Sun; Jun Xie; Guang-Jun Wang; Jing-Jing Tian; Gen Kaneko; Er-Meng Yu
Source:
Aquaculture 2023 v.562 pp. 738784
ISSN:
0044-8486
Subject:
proline,   etc   ; Ctenopharyngodon idella; absorption; amino acid composition; amino acid metabolism; aquaculture; arginine; carbohydrate content; crude fat; crude protein; digestion; freshwater; geosmin; glutamic acid; growth performance; metabolites; metabolomics; muscles; nitrates; nitrites; nutrient content; water content; water quality; weight gain;     Show all 24 Subjects
Abstract:
... Water quality is closely related to the nutritional and sensory qualities of grass carp, which has the largest aquaculture production among freshwater fishes. The purpose of this study was to explore the effects of nitrite and nitrate on the growth performance, nutrition composition and muscle flavor-associated metabolites of grass carp through an exposure experiment with varying concentrations (n ...
DOI:
10.1016/j.aquaculture.2022.738784

10. Integrated transcriptome and proteome unveiled distinct toxicological effects of long-term cadmium pollution on the silk glands of Pardosa pseudoannulata

Author:
Bo Lv; Yong Peng; Yuan-de Peng; Zhi Wang; Qi-sheng Song
Source:
Science of the total environment 2023 v.854 pp. 158841
ISSN:
0048-9697
Subject:
proline,   etc   ; Erinaceidae; Pardosa; alanine; amino acid metabolism; antioxidants; biomarkers; biosynthesis; cadmium; cell growth; cytoskeleton; environment; gene expression regulation; glutathione peroxidase; glutathione synthase; growth and development; malondialdehyde; methionine adenosyltransferase; models; paddies; peptides; peroxidase; phosphorylase; protein-protein interactions; proteome; silk; soil pollution; spiders; spidroins; toxicity; toxicology; transcriptome;     Show all 32 Subjects
Abstract:
... Cadmium (Cd) induces severe soil pollution worldwide and exerts adverse effects on paddy field arthropods. Spiders grant a novel perspective to assess the Cd-induced toxicity, yet the impacts of long-term Cd stress on spider silk glands and its underlying mechanism remain elusive. The study showed that Cd stress enervated the antioxidant system in the spider Pardosa pseudoannulata, manifested as t ...
DOI:
10.1016/j.scitotenv.2022.158841

11. BF3*OEt2 catalyzed synthesis of spiropyrrolidine frameworks via (3,5)-oxonium-ene cyclization

Author:
N. Prudhvi Raju; B. Jagan Mohan Reddy; P. Rasvan Khan; Saikiran Aita; G. Jithender Reddy; B. Sridhar; B.V. Subba Reddy
Source:
Tetrahedron letters 2022 v.107 pp. 154101
ISSN:
0040-4039
Subject:
proline,   etc   ; decane; hydroxybenzaldehyde;     Show all 3 Subjects
Abstract:
... γ-Hydroxyolefin derived from proline undergoes a smooth ene cyclization with aldehydes to produce the 7-oxa-1-azaspiro[4.5]decane scaffolds in good yields. Whereas the condensation of γ-hydroxyalkene with 2-hydroxybenzaldehyde affords the corresponding tetrahydro-2H-spiro[pyrano[3,2-c]chromene-3,2′-pyrrolidine derivatives in excellent yields. This is the first report on the ene cyclization of alde ...
DOI:
10.1016/j.tetlet.2022.154101

12. Microbial Proline Racemase–Proline Dehydrogenase Cascade for Efficient Production of D-proline and N-boc-5-hydroxy-L-proline from L-proline

Author:
Fanfan Zhang; Shiwen Xia; Hui Lin; Jiao Liu; Wenxin Huang
Source:
Applied biochemistry and biotechnology 2022 v.194 no.9 pp. 4135-4146
ISSN:
0273-2289
Subject:
proline; proline racemase,   etc   ; Escherichia coli; Pseudomonas pseudoalcaligenes; biotechnology; dehydrogenation; enantioselectivity; glutamic acid; oxidoreductases;     Show all 9 Subjects
Abstract:
... D-proline and N-boc-5-hydroxy-L-proline are key chiral intermediates in the production of eletriptan and saxagliptin, respectively. An efficient proline racemase–proline dehydrogenase cascade was developed for the enantioselective production of D-proline. It included the racemization of L-proline to DL-proline and the enantioselective dehydrogenation of L-proline in DL-proline. The racemization of ...
DOI:
10.1007/s12010-022-03980-y

13. Peptidyl Prolyl Isomerase A Modulates the Liquid–Liquid Phase Separation of Proline-Rich IDPs

Author:
Maria Babu; Filippo Favretto; Marija Rankovic; Markus Zweckstetter
Source:
Journal of the American Chemical Society 2022 v.144 no.35 pp. 16157-16163
ISSN:
1520-5126
Subject:
proline,   etc   ; dipeptides; isomerases; isomerization; separation;     Show all 5 Subjects
Abstract:
... Liquid–liquid phase separation (LLPS) of intrinsically disordered proteins (IDPs) and the action of molecular chaperones are tightly connected. An important class of molecular chaperones are peptidyl prolyl isomerases, which enhance the cis/trans-isomerization of proline. However, little is known about the impact of peptidyl prolyl isomerases on the LLPS of IDPs, which often contain many prolines. ...
DOI:
10.1021/jacs.2c07149

14. l- Proline, a resolution agent able to target both enantiomers of mandelic acid: an exciting case of stoichiometry controlled chiral resolution

Author:
Fuli Zhou; Laurent Collard; Koen Robeyns; Tom Leyssens; Oleksii Shemchuk
Source:
Chemical communications 2022 v.58 no.61 pp. 8560-8563
ISSN:
1364-548X
Subject:
proline,   etc   ; enantiomers; mandelic acid; stoichiometry;     Show all 4 Subjects
Abstract:
... We present a thought-provoking development in chiral resolution. Using a resolving agent of a given handedness, l-proline, we show that both R- and S-enantiomers of mandelic acid can be resolved from a racemic mixture simply by varying the stoichiometry. We are the first to report this specific feature, achieved by the existence of stoichiometrically diverse cocrystal systems between R- and S-mand ...
DOI:
10.1039/d2cc02942a

15. pH-Dependent Compaction of the Intrinsically Disordered Poly-E Motif in Titin

Author:
Sophia Manukian; Gerrick E. Lindberg; Emily Punch; Sudarshi Premawardhana Dassanayake Mudiyanselage; Matthew J. Gage
Source:
Biology 2022 v.11 no.9 pp. -
ISSN:
2079-7737
Subject:
proline,   etc   ; muscle protein; pH; peptides;     Show all 4 Subjects
Abstract:
... The conformational sensitivity of intrinsically disordered proteins to shifts in pH due to their high degree of charged residues has been recognized for well over a decade. However, the role of the non-ionizable residues in this pH sensitivity remains poorly understood. Our lab has been investigating the pH sensitivity of the poly-E motifs of the PEVK region of the muscle protein titin, which prov ...
DOI:
10.3390/biology11091302

16. Application of multi-wall carbon nanotubes supported l-proline in continuous flow catalysis

Author:
Huimin Xue; Mengyuan Ji; Sheng Huang; Yanhua Zhang
Source:
Tetrahedron letters 2022 v.101 pp. 153926
ISSN:
0040-4039
Subject:
proline,   etc   ; carbon nanotubes; catalytic activity; condensation reactions;     Show all 4 Subjects
Abstract:
... l-proline on multi-wall carbon nanotubes (l-proline/MWCNTs) catalysts doped with suitable auxiliary support materials are successfully applied in the continuous flow catalytic syntheses, including Aldol reaction, Mannich reaction and Knoevenagel condensation reaction. With the advantages of easy operation, high efficiency and excellent stability, this method is promising in large-scale synthesis. ...
DOI:
10.1016/j.tetlet.2022.153926

17. Effect of Solvents on Proline Modified at the Secondary Sphere: A Multivariate Exploration

Author:
Danilo M. Lustosa; Shahar Barkai; Ido Domb; Anat Milo
Source:
Journal of organic chemistry 2022 v.87 no.3 pp. 1850-1857
ISSN:
1520-6904
Subject:
proline,   etc   ; boronic acids; chloroform; organic chemistry; solvents;     Show all 5 Subjects
Abstract:
... The critical influence of solvent effects on proline-catalyzed aldol reactions has been extensively described. Herein, we apply multivariate regression strategies to probe the influence of different solvents on an aldol reaction catalyzed by proline modified at its secondary sphere with boronic acids. In this system, both in situ binding of the boronic acid to proline and the outcome of the aldol ...
DOI:
10.1021/acs.joc.1c02778

18. Proline selective labeling via on-site construction of naphthoxazole (NapOx)

Author:
Subhra Kanti Roy; Anisha Purkait; Rajib Shome; Saurav Das; Debapratim Das; Siddhartha Sankar Ghosh; Chandan K. Jana
Source:
Chemical communications 2022 v.58 no.39 pp. 5909-5912
ISSN:
1364-548X
Subject:
proline,   etc   ; bioimaging; chemoselectivity; cytotoxicity; membrane permeability; peptides;     Show all 6 Subjects
Abstract:
... Chemoselective construction of naphthoxazoles (NapOx) via a three-component annulation reaction enables proline selective labeling of peptides in solution or in solid-phase synthesis. The fluorogenic peptides possess low cytotoxicity, efficient cell membrane permeability and excellent bioimaging potential for biomedical applications. ...
DOI:
10.1039/d2cc01268e

19. SICKLE represses photomorphogenic development of Arabidopsis seedlings via HY5‐ and PIF4‐mediated signaling

Author:
Tao Li; Haojie Li; Hongmei Lian; Pengyu Song; Yulong Wang; Jie Duan; Zhaoqing Song; Yan Cao; Dongqing Xu; Jigang Li; Huiyong Zhang
Source:
Journal of integrative plant biology 2022 v.64 no.9 pp. 1706-1723
ISSN:
1672-9072
Subject:
proline,   etc   ; Arabidopsis; photomorphogenesis; phytochrome; seedlings; transcription (genetics);     Show all 6 Subjects
Abstract:
... Arabidopsis CONSTITUTIVELY PHOTOMORPHOGENIC1 (COP1) and PHYTOCHROME INTERACTING FACTORs (PIFs) are negative regulators, and ELONGATED HYPOCOTYL5 (HY5) is a positive regulator of seedling photomorphogenic development. Here, we report that SICKLE (SIC), a proline rich protein, acts as a novel negative regulator of photomorphogenesis. HY5 directly binds the SIC promoter and activates SIC expression i ...
DOI:
10.1111/jipb.13329

20. Decarboxylative Cyclization of Proline with o-Alkynylbenzaldehyde through an Unexploited 8π-Electrocyclization: A DFT Study

Author:
Hormoz Khosravi; Saber Mirzaei; Saeed Balalaie
Source:
Journal of organic chemistry 2022 v.87 no.15 pp. 9543-9550
ISSN:
1520-6904
Subject:
proline,   etc   ; Lewis bases; density functional theory; organic chemistry;     Show all 4 Subjects
Abstract:
... We employed density functional theory (DFT) methods to investigate the most plausible mechanism of cyclization/ring expansion of proline with o-alkynylbenzaldehyde. This one-pot reaction starts with the in situ formation of azomethine ylide, which can undergo three different reaction pathways to form the final product. Two mechanisms are based on nucleophilic addition and 4π-electrocyclization of ...
DOI:
10.1021/acs.joc.2c00509