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1. Harmful and protective roles of group V phospholipase A2: Current perspectives and future directions

Author:
Samuchiwal, Sachin K.; Balestrieri, Barbara
Source:
Biochimica et biophysica acta 2019 v.1864 no.6 pp. 819-826
ISSN:
1388-1981
Subject:
protective effect,   etc   ; adverse effects; immunology; phospholipase A2;     Show all 4 Subjects
Abstract:
... Group V Phospholipase A2 (Pla2g5) is a member of the PLA2 family of lipid-generating enzymes. It is expressed in immune and non-immune cell types and is inducible during several pathologic conditions serving context-specific functions. In this review, we recapitulate the protective and detrimental functions of Pla2g5 investigated through preclinical and translational approaches. This article is pa ...
DOI:
10.1016/j.bbalip.2018.10.001

2. Correction: Protective role of air potato (Dioscorea bulbifera) of yam family in myocardial ischemic reperfusion injury

Author:
VasanthiAddress at time of publication: Department of Biotechnology, School of Life Sciences, Pondicherry University, Puducherry, India., Hannah Rachel; Mukherjee, Subhendu; Ray, Diptarka; Jayachandran, Karuppiah Shanmugasundara Pandian; Lekli, Istvan; Das, Dipak Kumar
Source:
Food & function 2019 v.10 no.2 pp. 1243
ISSN:
2042-650X
Subject:
protective effect,   etc   ; Dioscorea bulbifera; reperfusion injury; yams;     Show all 4 Subjects
Abstract:
... Correction for ‘Protective role of air potato (Dioscorea bulbifera) of yam family in myocardial ischemic reperfusion injury’ by Hannah Rachel Vasanthi et al., Food Funct., 2010, 1, 278–283. ...
DOI:
10.1039/c9fo90005e

3. A core–shell heterostructured CuFe@NiFe Prussian blue analogue as a novel electrode material for high-capacity and stable capacitive deionization

Author:
Zhao, Yubo; Liang, Bolong; Wei, Xujie; Li, Kexun; Lv, Cuicui; Zhao, Yong
Source:
Journal of materials chemistry A 2019 v.7 no.17 pp. 10464-10474
ISSN:
2050-7496
Subject:
protective effect,   etc   ; deionization; desalination; electrochemistry; electrodes; energy; ions; iron; sodium;     Show all 9 Subjects
Abstract:
... Prussian blue analogues (PBAs) have recently been proposed as electrode materials for efficient capacitive deionization (CDI). However, there is a conflict between the desalination capacity and stability for single-component bimetallic PBAs, making it difficult to simultaneously achieve high desalination capacity and recyclability. To overcome this limitation, this study made an attempt to synthes ...
DOI:
10.1039/c8ta12433g

4. IL- 17A inhibits autophagic activity of HCC cells by inhibiting the degradation of Bcl2

Author:
Li, Sheng; Lin, Zhenwen; Zheng, Wang; Zheng, Lisheng; Chen, Xi; Yan, Zixing; Cheng, Zhuqin; Yan, Haiyi; Zheng, Cui; Guo, Peng
Source:
Biochemical and biophysical research communications 2019 v.509 no.1 pp. 194-200
ISSN:
0006-291X
Subject:
protective effect,   etc   ; autophagy; dissociation; hepatoma; interleukin-17; prognosis; starvation; viability;     Show all 8 Subjects
Abstract:
... Hepatocellular carcinoma (HCC) is associated with poor prognosis due to many unknowns about its inflammatory microenvironment. As a pivotal proinflammatory cytokine, IL-17A exerts a protective effect on the survival and function of HCC cells. It is widely accepted that IL-17A plays an important role in regulating autophagy. Bcl2, a key molecule promoting the survival of HCC cells, also plays an in ...
DOI:
10.1016/j.bbrc.2018.12.103

5. LncRNA COL1A2-AS1 inhibits the scar fibroblasts proliferation via regulating miR-21/Smad7 pathway

Author:
Nong, Qingwen; Li, Shuntang; Wu, Yajun; Liu, Daen
Source:
Biochemical and biophysical research communications 2018 v.495 no.1 pp. 319-324
ISSN:
0006-291X
Subject:
protective effect,   etc   ; antisense RNA; fibroblasts;     Show all 3 Subjects
Abstract:
... lncRNA COL1A2-AS1 (COL1A2 antisense RNA 1), a lncRNA overexpressed in hypertrophic scar, has been demonstrated to be involved in the hypertrophic scar formation. However, the mechanisms of lncRNA COL1A2-AS1 inhibiting the scar fibroblasts proliferation remains not well understood. In this study, we demonstrated that lncRNA COL1A2-AS1 was upregulated in hypertrophic scar tissue and fibroblasts, and ...
DOI:
10.1016/j.bbrc.2017.11.027

6. Rainfall erosivity in interrill areas: Insights about the choice of an erosive factor

Author:
Nouhou-Bako, A.; Darboux, F.; James, F.; Lucas, C.
Source:
Catena 2019 v.180 pp. 24-31
ISSN:
0341-8162
Subject:
protective effect,   etc   ; erodibility; experimental design; interrill erosion; rain; shear stress; soil erosion models;     Show all 7 Subjects
Abstract:
... Defining a suitable erosive factor for interrill erosion has been a long-going discussion that was not resolved by experimental results. In this paper, by using computational fluid simulations of individual raindrop impacts, the relevance of four erosive factors was assessed for a range of soil resistance, rainfall type and water layer depth. Computation results show that the erosivity exponent as ...
DOI:
10.1016/j.catena.2019.02.025

7. Microevolution or wide tolerance? Level of stress proteins in the beet armyworm Spodoptera eqigua hübner (Lepidoptera: Noctuidae) exposed to cadmium for over 150 generations

Author:
Tarnawska, Monika; Kafel, Alina; Augustyniak, Maria; Rost-Roszkowska, Magdalena; Babczyńska, Agnieszka
Source:
Ecotoxicology and environmental safety 2019 v.178 pp. 1-8
ISSN:
0147-6513
Subject:
protective effect,   etc   ; Spodoptera exigua; cadmium; heat shock proteins; insects; larvae; midgut; protein content; pupae; rearing;     Show all 10 Subjects
Abstract:
... The aim of this study was to investigate whether the cadmium tolerance developed in the beet armyworm Spodoptera exigua selected for over 150 generations may be related to synthesis of the stress proteins metallothioneins (Mts) and 70 kDa heat shock proteins (HSP70). To achieve this, six S. exigua strains (control, k), 150-generation Cd exposure strain (cd), and four 18-generation Cd exposure stra ...
DOI:
10.1016/j.ecoenv.2019.04.017

8. Protective effect of hydroxytyrosol and rosemary extract in a comparative study of the oxidative stability of Echium oil

Author:
Bañares, Celia; Martin, Diana; Reglero, Guillermo; Torres, Carlos F.
Source:
Food chemistry 2019 v.290 pp. 316-323
ISSN:
0308-8146
Subject:
protective effect,   etc   ; Echium; antioxidants; differential scanning calorimetry; oxidation; oxidative stability; polar compounds; rosemary; temperature; vegetable oil;     Show all 10 Subjects
Abstract:
... The oxidative stability of Echium oil has been studied by two accelerated oxidation methodologies namely Rancimat and differential scanning calorimetry at selected temperatures in the range 50–110 °C. Kinetic analyses have provided Arrhenius parameters, oxidative stability indexes (OSI), temperature coefficients (tcoef), Q10 and OSI at 20 °C (OSI20) for both methodologies focussing on secondary an ...
DOI:
10.1016/j.foodchem.2019.03.141

9. A simple model to estimate emission of wind-blown particles from a granular bed in comparison to wind tunnel experiments

Author:
Ferreira, M.C.S.; Furieri, B.; A., Ould El Moctar; Harion, J.-L.; Valance, A.; Dupont, P.; Reis, N.C.; Santos, J.M.
Source:
Geomorphology 2019 v.335 pp. 1-13
ISSN:
0169-555X
Subject:
protective effect,   etc   ; air; dust emissions; models; particle size distribution; pavements; sand; wind; wind erosion; wind tunnels;     Show all 10 Subjects
Abstract:
... Dust emissions due to aeolian erosion of exposed granular materials are strongly influenced by grain size distribution. Non-erodible particles that are too heavy to be lifted into the air play a protective role in the aeolian erosion process attenuating emission, which is known as the pavement phenomenon. To date, there is no approach that reliably predicts the reduction in emissions caused by the ...
DOI:
10.1016/j.geomorph.2019.03.004

10. Effectiveness of hole plate-type sand barriers in reducing aeolian sediment flux: Evaluation of effect of hole size

Author:
Chen, Boyu; Cheng, Jianjun; Xin, Lingui; Wang, Rui
Source:
Aeolian research 2019 v.38 pp. 1-12
ISSN:
1875-9637
Subject:
protective effect,   etc   ; disasters; geometry; mathematical models; porosity; railroads; sand; wind speed; wind tunnels; Gobi Desert;     Show all 10 Subjects
Abstract:
... Hole plate-type sand barriers can effectively control wind-sand disasters along the railways running through the windy Gobi desert region, and the hole diameter of hole plate is the key geometric parameter influencing their protective effect. To determine the effect of hole diameter on the wind-sand flow field of hole plate-type sand barriers, in this study, numerical simulations and wind tunnel t ...
DOI:
10.1016/j.aeolia.2019.03.001

11. Sacculatane diterpenoids from the Chinese liverwort Pellia epiphylla with protection against H2O2-induced apoptosis of PC12 cells

Author:
Li, Yi; Sun, Yong; Zhu, Mingzhu; Zhu, Rongxiu; Zhang, Jiaozhen; Zhou, Jinchuan; Wang, Tian; Qiao, Yanan; Lou, Hongxiang
Source:
Phytochemistry 2019 v.162 pp. 173-182
ISSN:
0031-9422
Subject:
protective effect,   etc   ; antioxidant activity; apoptosis; diterpenoids; mosses and liverworts; quinine; spectral analysis;     Show all 7 Subjects
Abstract:
... Eight previously undescribed sacculatane diterpenoids, epiphyllins A−H, and one unknown bibenzyl-based isopentene along with seven known compounds were isolated from the Chinese liverwort Pellia epiphylla (L.) Corda. Their structures were established unequivocally on the basis of spectroscopic data and CD measurement. The quinine reductase-inducing activity evaluation demonstrated that epiphyllins ...
DOI:
10.1016/j.phytochem.2019.03.007

12. The protective role of autophagy in sepsis

Author:
Feng, Ying; Liu, Boyi; Zheng, Xiang; Chen, Li; Chen, Wei; Fang, Zhicheng
Source:
Microbial pathogenesis 2019 v.131 pp. 106-111
ISSN:
0882-4010
Subject:
protective effect,   etc   ; apoptosis; autophagy; defense mechanisms; immune response; inflammation; metabolism; pathogens; sepsis (infection); therapeutics;     Show all 10 Subjects
Abstract:
... Sepsis is characterized by life-threatening organ dysfunction caused by a deregulated host response to infection. Autophagy is one of the innate immune defense mechanisms against microbial attack. Previous studies have demonstrated that autophagy is activated initially in sepsis, followed by a subsequent phase of impairment. A number of sepsis-related studies have shown that autophagy plays a prot ...
DOI:
10.1016/j.micpath.2019.03.039

13. Understanding relaxin signalling at the cellular level

Author:
Valkovic, Adam L.; Bathgate, Ross AD.; Samuel, Chrishan S.; Kocan, Martina
Source:
Molecular and cellular endocrinology 2019 v.487 pp. 24-33
ISSN:
0303-7207
Subject:
protective effect,   etc   ; G-protein coupled receptors; animal tissues; fibrosis; ligands; peptide receptors; relaxin; signal transduction; vasodilation;     Show all 9 Subjects
Abstract:
... The peptide hormone relaxin mediates many biological actions including anti-fibrotic, vasodilatory, angiogenic, anti-inflammatory, anti-apoptotic, and organ protective effects across a range of tissues. At the cellular level, relaxin binds to the G protein-coupled receptor relaxin family peptide receptor 1 (RXFP1) to activate a variety of downstream signal transduction pathways. This signalling ca ...
DOI:
10.1016/j.mce.2018.12.017

14. Disruptive membrane interactions of alpha-synuclein aggregates

Author:
Iyer, Aditya; Claessens, Mireille M.A.E.
Source:
Biochimica et biophysica acta 2019 v.1867 no.5 pp. 468-482
ISSN:
1570-9639
Subject:
protective effect,   etc   ; Parkinson disease; amyloid; cell membranes; phospholipids; physicochemical properties; point mutation; post-translational modification;     Show all 8 Subjects
Abstract:
... Alpha synuclein (αS) is a ~14 kDa intrinsically disordered protein. Decades of research have increased our knowledge on αS yet its physiological function remains largely elusive. The conversion of monomeric αS into oligomers and amyloid fibrils is believed to play a central role of the pathology of Parkinson's disease (PD). It is becoming increasingly clear that the interactions of αS with cellula ...
DOI:
10.1016/j.bbapap.2018.10.006

15. Effect of extraction system and grape variety on anti-influenza compounds from wine production residue

Author:
Bekhit, Alaa El-Din A.; Cheng, Vern Jou; Zhang, Hongxia; Mros, Sonya; Mohamed Ahmed, Isam A.; Al-Juhaimi, Fahad Y.; Bekhit, Adnan A.; McConnell, Michelle
Source:
Food control 2019 v.99 pp. 180-189
ISSN:
0956-7135
Subject:
protective effect,   etc   ; acetone; ethanol; grapes; methanol; phenolic compounds; pomace; pomace extracts; seed extracts; seeds; solvents; winemaking;     Show all 12 Subjects
Abstract:
... The effects of extraction process using three different solvents [50% aqueous acetone (Ace/w), 50% aqueous ethanol (Eth/w) or 50% aqueous methanol (Meth/w)] and wine production residue (seeds, skin and pomace) from Pinot noir [PN] and Pinot meunier [PM] on the phenolic profile and anti-influenza activity of their extracts were determined. Meth/w extracts resulted in the lowest (P < 0.05) total phe ...
DOI:
10.1016/j.foodcont.2018.12.036

16. Oat fiber inhibits atherosclerotic progression through improving lipid metabolism in ApoE−/− mice

Author:
Han, Shufen; Zhang, Ru; Gao, Hui; Yang, Jing; Zhang, Weiguo; Qin, Liqiang
Source:
Journal of functional foods 2019 v.56 pp. 14-20
ISSN:
1756-4646
Subject:
protective effect,   etc   ; atherosclerosis; blood serum; cholesterol; death; high fat diet; intestinal absorption; lipid metabolism; mice; oats;     Show all 10 Subjects
Abstract:
... Cardiovascular diseases caused by atherosclerosis have become one of the leading cause of death. The aim of the present study was to explore how oat fiber regulated lipid metabolism and to elucidate its anti-atherosclerotic potential in ApoE−/− mice. Animals were daily fed a high-fat diet without or with 0.8% oat fiber for 18 weeks. Both serum total cholesterol and low-density cholesterol levels d ...
DOI:
10.1016/j.jff.2019.02.046

17. Appropriate dose of ethanol exerts anti-senescence and anti-atherosclerosis protective effects by activating ALDH2

Author:
Xue, Li; Zhu, Wenyong; Yang, Feihong; Dai, Shuai; Han, Ziqi; Xu, Feng; Guo, Ping; Chen, Yuguo
Source:
Biochemical and biophysical research communications 2019 v.512 no.2 pp. 319-325
ISSN:
0006-291X
Subject:
protective effect,   etc   ; agonists; alcohol drinking; aldehyde dehydrogenase; atherosclerosis; cell senescence; dose response; endothelium; ethanol; mice; resveratrol;     Show all 11 Subjects
Abstract:
... Moderate alcohol consumption has been shown to reduce atherosclerosis-associated diseases. As shown in our earlier works, ethanol has a dose-dependent protective effects against endothelial cellular senescence by activating aldehyde dehydrogenase 2 (ALDH2) in vitro. However, whether ethanol administration possesses anti-atherosclerosis properties and whether ALDH2 is involved in the underlying mec ...
DOI:
10.1016/j.bbrc.2019.03.037

18. Antioxidant effect of resveratrol in single red blood cells measured by thermal fluctuation spectroscopy

Author:
Gallardo, María José; Suwalsky, Mario; Ramírez, Diego; Tapia, Jorge; Sepulveda, Benjamín
Source:
Archives of biochemistry and biophysics 2019 v.665 pp. 30-35
ISSN:
0003-9861
Subject:
protective effect,   etc   ; antioxidant activity; cell membranes; deformation; erythrocytes; humans; mechanical properties; oxidants; resveratrol; spectroscopy;     Show all 10 Subjects
Abstract:
... The human red blood cell (RBC) membrane has significant elastic capabilities which can be described measuring typical membrane edge fluctuations and mechanical properties by optical techniques. The RBC elastic properties can be affected by changes in the surrounding media. In an attempt to elucidate the molecular mechanisms of the interaction of resveratrol with the red cell membrane and of its an ...
DOI:
10.1016/j.abb.2019.02.011

19. Characterization of polysaccharide fractions from fruit of Actinidia arguta and assessment of their antioxidant and antiglycated activities

Author:
Zhu, Rugang; Zhang, Xinyu; Wang, Yu; Zhang, Lijiao; Zhao, Jing; Chen, Gang; Fan, Jungang; Jia, Youfeng; Yan, Fengwen; Ning, Chong
Source:
Carbohydrate polymers 2019 v.210 pp. 73-84
ISSN:
0144-8617
Subject:
protective effect,   etc   ; Actinidia arguta; antioxidant activity; antioxidants; fruits; glycation; iron; lipid peroxidation; moieties; pectins; thiols;     Show all 11 Subjects
Abstract:
... A novel cell-wall polysaccharides (AAPs) were extracted from the fruits of Actinidia arguta and separated into four parts which were named water-eluted polysaccharide (WPS), salt-eluted polysaccharide (SPS)-1, SPS-2 and SPS-3. The monosaccharide composition and structural analysis showed that SPS-3 and SPS-2 were homogalacturonan (HG)-rich pectin, SPS-1 was rhamnogalacturonan (RG)-rich pectin and ...
DOI:
10.1016/j.carbpol.2019.01.037

20. Protective effects of 3β-angeloyloxy-8β, 10β-dihydroxyeremophila-7(11)-en-12, 8α-lactone on paraquat-induced oxidative injury in SH-SY5Y cells

Author:
Wang, Qi-Lin; Guo, Chao; Qi, Jie; Ma, Jia-Hui; Liu, Fang-Yuan; Lin, Shi-Qi; Zhang, Cai-Yun; Xie, Wei-Dong; Zhuang, Jing-Jing; Li, Xia
Source:
Journal of Asian natural products research 2019 v.21 no.4 pp. 364-376
ISSN:
1477-2213
Subject:
protective effect,   etc   ; Parkinson disease; caspase-3; caspase-9; oxidative stress; paraquat; superoxide dismutase;     Show all 7 Subjects
Abstract:
... 3β-Angeloyloxy-8β,10β-dihydroxyeremophila-7(11)-en-12,8α-lactone (FJ1) inhibited effectively paraquat (PQ)-induced injury in SH-SY5Y cells. In this way, FJ1 was shown to reverse the PQ-induced activation of caspase-9 and caspase-3, the increase in Bax/Bcl-2 ratio, and the release of cytochrome c. The mechanism was associated with a reduction of oxidative stress, including the decrease in the level ...
DOI:
10.1080/10286020.2017.1423057