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1. Melatonin attenuated the behavioral despair induced by acute neurogenic stress through blockade of N-methyl D-aspartate receptors in mice

Author:
Hajmirzaeyian, Arwin; Chamanara, Mohsen; Rashidian, Amir; Shakyba, Saied; Nassireslami, Ehsan; Akhavan-Sigari, Reza
Source:
Heliyon 2021 v.7 no.1 pp. e05900
ISSN:
2405-8440
Subject:
protective effect,   etc   ; agonists; anxiety; ketamine; locomotion; melatonin;     Show all 6 Subjects
Abstract:
... It has been well documented that administration of melatonin could reveal antidepressant-like effect in rodents. However, the protective effect of melatonin on stress-induced depression/anxiety and its underlying mechanism is yet to be understood. In this regard, in the current study, acute foot-shock stress (FSS) was used to evaluate the antidepressant-like effect of melatonin on neurogenic stres ...
DOI:
10.1016/j.heliyon.2021.e05900

2. Wave transmission and drag coefficients through dense cylinder arrays: Implications for designing structures for mangrove restoration

Author:
Gijón Mancheño, A.; Jansen, W.; Uijttewaal, W.S.J.; Reniers, A.J.H.M.; van Rooijen, A.A.; Suzuki, T.; Etminan, V.; Winterwerp, J.C.
Source:
Ecological engineering 2021 v.165 pp. 106231
ISSN:
0925-8574
Subject:
protective effect,   etc   ; bamboos; habitats; humans; hydrodynamics; models; vegetation;     Show all 7 Subjects
Abstract:
... Mangrove vegetation constitutes a natural coastal defence against waves and erosion. Despite their protective role, mangrove ecosystems have experienced continuous degradation over the last decades due to human causes. At retreating mangrove coastlines, bamboo structures are built to create new habitat for mangrove colonization. Existing structures have experienced mixed rates of success due to th ...
DOI:
10.1016/j.ecoleng.2021.106231

3. Linoleic acid induces different metabolic modes in two Bifidobacterium breve strains with different conjugated linoleic acid-producing abilities

Author:
Gao, He; Yang, Bo; Stanton, Catherine; Ross, R. Paul; Zhang, Hao; Chen, Haiqin; Chen, Wei
Source:
Lebensmittel-Wissenschaft + [i.e. und] Technologie 2021 v.142 pp. 110974
ISSN:
0023-6438
Subject:
protective effect,   etc   ; ; Bifidobacterium breve; antioxidants; cysteine; glutathione; mannitol; metabolomics;     Show all 8 Subjects
Abstract:
... Frequently, Bifidobacterium breve strains are found to be CLA-producers. Previous studies revealed that free linoleic acid inhibited the growth of bifidobacterial strains, however, the reason why bifidobacteria with different CLA-producing abilities exhibit similar adaptive modes to linoleic acid (LA) stress is still unknown. We used B. breve strains CCFM683 and CCFM1025, which exhibit 85% and 0% ...
DOI:
10.1016/j.lwt.2021.110974

4. Moderate Consumption of Beer and Its Effects on Cardiovascular and Metabolic Health: An Updated Review of Recent Scientific Evidence

Author:
Marcos, Ascensión; Serra-Majem, Lluís; Pérez-Jiménez, Francisco; Pascual, Vicente; Tinahones, Francisco José; Estruch, Ramón
Source:
Nutrients 2021 v.13 no.3
ISSN:
2072-6643
Subject:
protective effect,   etc   ; alcohol drinking; alcohols; beers; cardiovascular diseases; mortality;     Show all 6 Subjects
Abstract:
... There is growing interest in the potential health-related effects of moderate alcohol consumption and, specifically, of beer. This review provides an assessment of beer-associated effects on cardiovascular and metabolic risk factors to identify a consumption level that can be considered “moderate”. We identified all prospective clinical studies and systematic reviews that evaluated the health effe ...
DOI:
10.3390/nu13030879

5. Protective effect of carrier matrices on survival of Lactobacillus plantarum WCFS1 during single droplet drying explained by particle morphology development

Author:
Siemons, I.; Vaessen, E.M.J.; Oosterbaan van Peski, S.E.; Boom, R.M.; Schutyser, M.A.I.
Source:
Journal of food engineering 2021 v.292 pp. 110263
ISSN:
0260-8774
Subject:
protective effect,   etc   ; Lactobacillus plantarum; droplets; evaporation; lactic acid;     Show all 5 Subjects
Abstract:
... Spray drying can be used to manufacture powder ingredients with lactic acid bacteria. Carrier matrices are used to increase survival of bacteria during drying; however, it is not exactly known why some matrices provide better protection than others. Depending on the carrier matrix and the drying conditions, different powder particle morphologies are obtained. Here, we employed single droplet dryin ...
DOI:
10.1016/j.jfoodeng.2020.110263

6. CTRP9 alleviates foam cells apoptosis by enhancing cholesterol efflux

Author:
Lei, Shengyun; Chen, Jiying; Song, Chengxiang; Li, Jun; Zuo, Anju; Xu, Dan; Li, Tingting; Guo, Yuan
Source:
Molecular and cellular endocrinology 2021 v.522 pp. 111138
ISSN:
0303-7207
Subject:
protective effect,   etc   ; Adenoviridae; apoptosis; cholesterol; endocrinology; foam cells; proteins;     Show all 7 Subjects
Abstract:
... The apoptosis of foam cells leads to instability of atherosclerotic plaques. This study was designed to explore the protective role of CTRP9 in foam cell apoptosis. In our experiment, CTRP9 alleviated foam cell apoptosis. Meanwhile, CTRP9 upregulated the expression of proteins important for cholesterol efflux, such as LXRα, CYP27A1, ABCG1 and ABCA1, and improved cholesterol efflux in foam cells. M ...
DOI:
10.1016/j.mce.2020.111138

7. ADAM10 and ADAM17 are degraded by lysosomal pathway via asparagine endopeptidase

Author:
Zhang, Xingyu; Tang, Li; Zhang, Zhentao
Source:
Biochemical and biophysical research communications 2021 v.537 pp. 15-21
ISSN:
0006-291X
Subject:
protective effect,   etc   ; amyloid; asparagine; brain; cysteine proteinases; metalloproteinases; pathogenesis; research;     Show all 8 Subjects
Abstract:
... A disintegrin and metalloproteinases 10 (ADAM10) and ADAM17 are transmembrane metalloproteinases that cleave the membrane-anchored proteins. They act as α-secretase that cleaves amyloid precursor protein (APP), precluding the production of amyloid-β, thus protecting against the onset of Alzheimer’s disease (AD). However, the degradation pathway of ADAM10 and ADAM17 remains unknown. In this study, ...
DOI:
10.1016/j.bbrc.2020.12.063

8. Duration of breastfeeding, age at introduction of complementary foods and allergy-related diseases: a prospective cohort study

Author:
Ekelund, Louise; Gloppen, Inga; Øien, Torbjørn; Simpson, Melanie Rae
Source:
International breastfeeding journal 2021 v.16 no.1 pp. 5
ISSN:
1746-4358
Subject:
protective effect,   etc   ; asthma; breast feeding; child health; cohort studies; complementary foods; diet; eczema; risk reduction; Norway;     Show all 10 Subjects
Abstract:
... BACKGROUND: The influences of breastfeeding and infant diet in the prevention of allergy-related diseases are uncertain and many of the studies conducted on the topic are limited by methodological challenges. Our aim was to assess whether the duration of breastfeeding and age at complementary food introduction affected the prevalence of asthma, wheeze, allergic rhinoconjunctivitis (ARC) and eczema ...
DOI:
10.1186/s13006-020-00352-2

9. Fluorescence correlation spectroscopy to unravel the interactions between macromolecules in wine

Author:
Mierczynska-Vasilev, Agnieszka; Bindon, Keren; Gawel, Richard; Smith, Paul; Vasilev, Krasimir; Butt, Hans-Jurgen (Hans-Jürgen); Koynov, Kaloian
Source:
Food chemistry 2021 v.352 pp. 129343
ISSN:
0308-8146
Subject:
protective effect,   etc   ; bovine serum albumin; diffusivity; fluorescence correlation spectroscopy; food chemistry; polysaccharides; protein conformation; wines;     Show all 8 Subjects
Abstract:
... In this work, the interaction of wine macromolecules with a bovine serum albumin (BSA) was investigated using fluorescence correlation spectroscopy (FCS). FCS offers the opportunity to study molecular and macromolecular aggregation without disturbing the wine by introducing only very small amounts of fluorescently labelled molecules to the system. It was observed that the diffusion coefficient of ...
DOI:
10.1016/j.foodchem.2021.129343

10. Relationships among perceived stress, emotional eating, and dietary intake in college students: Eating self-regulation as a mediator

Author:
Ling, Jiying; Zahry, Nagwan R.
Source:
Appetite 2021 v.163 pp. 105215
ISSN:
0195-6663
Subject:
protective effect,   etc   ; appetite; cross-sectional studies; demographic statistics; females; food intake; obesity; stress management; surveys;     Show all 9 Subjects
Abstract:
... This study aimed to examine the relationships among perceived stress, eating self-regulation, emotional eating, and dietary intake among undergraduate college students. This cross-sectional study was conducted with 523 students recruited from Amazon Mechanical Turk. All participants completed an online survey that assessed perceived stress, eating self-regulation, emotional eating, dietary intake, ...
DOI:
10.1016/j.appet.2021.105215

11. Portable and quantitative detection of carbendazim based on the readout of a thermometer

Author:
Fu, Ruijie; Zhou, Jing; Liu, Yanlin; Wang, Yiwen; Liu, Haoran; Pang, Junxiao; Cui, Yongliang; Zhao, Qiyang; Wang, Chengqiu; Li, Zhixia; Jiao, Bining; He, Yue
Source:
Food chemistry 2021 v.351 pp. 129292
ISSN:
0308-8146
Subject:
protective effect,   etc   ; assays; carbendazim; detection; food chemistry; food safety; human health; irradiation; nanogold; oligonucleotides; temperature; thermometers;     Show all 12 Subjects
Abstract:
... The detection of carbendazim (CBZ) is important for food safety and human health. However, most current analytical methods require large instruments and highly trained operators. In order to solve this problem, herein, an innovative portable and quantitative photothermal assay platform relying on a thermometer readout for the detection of CBZ has been developed. Gold nanoparticles (AuNPs), which e ...
DOI:
10.1016/j.foodchem.2021.129292

12. Protective effects of three structurally similar polyphenolic compounds against oxidative damage and their binding properties to human serum albumin

Author:
Zhang, Chuanying; Guan, Jiao; Zhang, Jiaxing; Yang, Jichen; Wang, Xiaoli; Peng, Xin
Source:
Food chemistry 2021 v.349 pp. 129118
ISSN:
0308-8146
Subject:
protective effect,   etc   ; antioxidant activity; chemical structure; degradation; fluorescence; food chemistry; health services; human serum albumin; polyphenols;     Show all 9 Subjects
Abstract:
... Brazilin (Bra), hematoxylin (Hto) and hematein (Hte) are structurally similar polyphenols having rich biological activities, but their antioxidant ability has not been well studied. Here, their protective ability against human serum albumin (HSA) oxidative degradation were investigated using 2,2′-Azobis (2-methylpropionamidine) dihydrochloride (AAPH), NaClO and Fenton like reactions methods. The r ...
DOI:
10.1016/j.foodchem.2021.129118

13. Vitamin C, protein, and dietary fibre contents as affected by genotype, agro-climatic conditions, and cooking method on tubers of Solanum tuberosum Group Phureja

Author:
Thomas, Séverine; Vásquez-Benítez, Juan-David; Cuéllar-Cepeda, Fabio-Alexander; Mosquera-Vásquez, Teresa; Narváez-Cuenca, Carlos-Eduardo
Source:
Food chemistry 2021 v.349 pp. 129207
ISSN:
0308-8146
Subject:
protective effect,   etc   ; Solanum tuberosum; ascorbic acid; dietary fiber; food chemistry; genotype; potatoes; variability; variance;     Show all 9 Subjects
Abstract:
... The simultaneous effect of genotype, agro-climatic conditions, and cooking method was evaluated towards the contents of vitamin C, protein, and soluble, insoluble, and total dietary fibre in potato tubers from the Group Phureja. Within the tested treatments, vitamin C was affected the most (9.4–85.1 mg/100 g DW), followed by insoluble dietary fibre (3.9–16.6 g/100 DW), soluble dietary fibre (1.0–3 ...
DOI:
10.1016/j.foodchem.2021.129207

14. The protective role of hydrophilic tetrahydroxylated bile acids (THBA)

Author:
Sheps, Jonathan A.; Wang, Renxue; Wang, Jianshe; Ling, Victor
Source:
Biochimica et biophysica acta 2021 v.1866 no.7 pp. 158925
ISSN:
1388-1981
Subject:
protective effect,   etc   ; bile; bile acids; bile salts; cholestasis; cytotoxicity; human health; hydrophilicity; liver; phospholipids; transporters;     Show all 11 Subjects
Abstract:
... Bile acids are key components of bile required for human health. In humans and mice, conditions of reduced bile flow, cholestasis, induce bile acid detoxification by producing tetrahydroxylated bile acids (THBA), more hydrophilic and less cytotoxic than the usual bile acids, which are typically di- or tri-hydroxylated. Mice deficient in the Bile Salt Export Pump (Bsep, or Abcb11), the primary bile ...
DOI:
10.1016/j.bbalip.2021.158925

15. Reduction of enzymatic degradation of insulin via encapsulation in a lipidic bicontinuous cubic phase

Author:
Strachan, Jamie B.; Dyett, Brendan P.; Jones, Nykola C.; Hoffmann, Søren Vrønning; Valery, Celine; Conn, Charlotte E.
Source:
Journal of colloid and interface science 2021 v.592 pp. 135-144
ISSN:
0021-9797
Subject:
protective effect,   etc   ; chymotrypsin; digestive tract; drugs; encapsulation; insulin; lipids; pH; small intestine; stomach;     Show all 10 Subjects
Abstract:
... Oral delivery of the protein drug insulin is not currently possible due to rapid degradation of the secondary structure in low pH conditions in the stomach and under the influence of digestive enzymes in the gastrointestinal tract. Effective oral delivery of insulin and other protein- or peptide-based drugs will, therefore, require encapsulation in a material or nanoparticle. Herein we investigate ...
DOI:
10.1016/j.jcis.2021.02.027

16. Silicon oxide-protected nickel nanoparticles as biomass-derived catalysts for urea electro-oxidation

Author:
Yuan, Meijuan; Guo, Xiaotian; Li, Nan; Pang, Huan
Source:
Journal of colloid and interface science 2021 v.589 pp. 56-64
ISSN:
0021-9797
Subject:
protective effect,   etc   ; bamboos; biomass; carbon; electrochemistry; energy conversion; nanosheets; nickel; silicon; urea; wastewater;     Show all 11 Subjects
Abstract:
... The urea electro-oxidation reaction (UOR) is explored as a new technique for energy conversion and the removal of urea via electrochemical means in wastewater. Nickel (Ni) nanoparticles grown on nanosheets were prepared by a facile hydrothermal reaction and a subsequent calcination process of silicon oxide/nitrogen-doped carbon (SiOₓ/NC) as the precursor, in which SiOₓ/NC with a natural three-dime ...
DOI:
10.1016/j.jcis.2020.12.100

17. Lack of neonatal Fc receptor does not diminish the efficacy of the HSV-1 0ΔNLS vaccine against ocular HSV-1 challenge

Author:
Carr, Daniel J.J.; Berube, Amanda N.; Filiberti, Adrian; Gmyrek, Grzegorz B.
Source:
Vaccine 2021 v.39 no.18 pp. 2526-2536
ISSN:
0264-410X
Subject:
protective effect,   etc   ; Human alphaherpesvirus 1; angiogenesis; blood serum; cornea; memory; opacity; vaccines; viruses;     Show all 9 Subjects
Abstract:
... The neonatal Fc receptor (FcRn) is constitutively expressed in the cornea and is up-regulated in response to herpes simplex virus type 1 (HSV-1). Previously, we found targeting cornea FcRn expression by small interfering RNA-mediated knockdown reduced the local efficacy of HSV-1 0ΔNLS vaccinated C57BL/6 mice against ocular challenge with HSV-1. The current study was undertaken to evaluate the HSV- ...
DOI:
10.1016/j.vaccine.2021.03.075

18. Mild hypothermia pretreatment extenuates liver ischemia-reperfusion injury through Rab7-mediated autophagosomes-lysosomes fusion

Author:
Liu, Anxiong; Wang, Wei; Lu, Zhongshan; Liu, Zhongzhong; Zhou, Wei; Zhong, Zibiao; Ye, Qifa
Source:
Biochemical and biophysical research communications 2021 v.550 pp. 15-21
ISSN:
0006-291X
Subject:
protective effect,   etc   ; apoptosis; autophagosomes; autophagy; fluorescent antibody technique; hypothermia; liver; lysosomes; prognosis; protein synthesis; research; therapeutics;     Show all 12 Subjects
Abstract:
... Liver ischemia-reperfusion (IR) injury is an unavoidable pathological process in transplantation, closely related to poor prognosis. To date, there has been no clear therapeutic measure. We previously reported that mild hypothermia (MH), a widely used therapy, can exert significant protective effect against liver IR injury. Among the multiple mechanisms underlying the therapeutic effect of MH, aut ...
DOI:
10.1016/j.bbrc.2021.02.125

19. Inhibition of Notch1 signaling reduces hepatocyte injury in nonalcoholic fatty liver disease via autophagy

Author:
Zhang, Min; Wu, Pengbo; Li, Ming; Guo, Yitian; Tian, Tian; Liao, Xingchen; Tan, Shiyun
Source:
Biochemical and biophysical research communications 2021 v.547 pp. 131-138
ISSN:
0006-291X
Subject:
protective effect,   etc   ; apoptosis; autophagy; chloroquine; fatty liver; lipids; metabolism; mitochondria; oxidative stress; research;     Show all 10 Subjects
Abstract:
... Nonalcoholic fatty liver disease (NAFLD) has become the most common cause of chronic liver disease worldwide and an urgent target for clinical intervention. Notch1 signaling pathway activity was found to be related to the severity of NAFLD, but the specific mechanism is not precise. Here, we investigated the potential mechanisms of Notch1 signaling in the development of NAFLD. Firstly, we found th ...
DOI:
10.1016/j.bbrc.2021.02.039

20. Coffee consumption and breast cancer risk: a narrative review in the general population and in different subtypes of breast cancer

Author:
Nehlig, Astrid; Reix, Nathalie; Arbogast, Pauline; Mathelin, Carole
Source:
European journal of nutrition 2021 v.60 no.3 pp. 1197-1235
ISSN:
1436-6207
Subject:
protective effect,   etc   ; breast neoplasms; caffeine; mutation; nutrition; postmenopause; premenopause; radiotherapy; risk; surgery; tamoxifen; tumor suppressor proteins;     Show all 12 Subjects
Abstract:
... PURPOSE: Most of the existing literature reports no association or a slight negative association between coffee consumption and the risk of developing breast cancer. However, the level of risk differs when considering various subgroups, such as menopausal status, hormonal status of the tumor or genetic mutations. The present review based on a literature search sets the point on the potential influ ...
DOI:
10.1007/s00394-020-02465-0