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1. Assessment of the protective effect of PMMA on water immersion ageing of flame retarded PLA/PMMA blends

Author:
Mangin, R.; Vahabi, H.; Sonnier, R.; Chivas-Joly, C.; Lopez-Cuesta, J.-M.; Cochez, M.
Source:
Polymer degradation and stability 2020 v.174 pp. 109104
ISSN:
0141-3910
Subject:
protective effect,   etc   ; calorimeters; equations; glass transition temperature; phosphorus; polymethylmethacrylate;     Show all 6 Subjects
Abstract:
... The incorporation of PMMA into phosphorus-containing flame retarded PLA was assessed as a possible strategy to reduce the sensitivity of the material to ageing in water at 70 °C. PLA and PMMA are miscible and the unique glass transition temperature can be easily controlled by a proper amount of PMMA according to Gordon-Taylor equation. Water penetration as well as phosphorus release was reduced wh ...
DOI:
10.1016/j.polymdegradstab.2020.109104

2. Transthyretin Inhibits Primary and Secondary Nucleations of Amyloid-β Peptide Aggregation and Reduces the Toxicity of Its Oligomers

Author:
Ghadami, Seyyed Abolghasem; Chia, Sean; Ruggeri, Francesco Simone; Meisl, Georg; Bemporad, Francesco; Habchi, Johnny; Cascella, Roberta; Dobson, Christopher M.; Vendruscolo, Michele; Knowles, Tuomas P. J.; Chiti, Fabrizio
Source:
Biomacromolecules 2020 v.21 no.3 pp. 1112-1125
ISSN:
1526-4602
Subject:
protective effect,   etc   ; Alzheimer disease; brain; fluorescence; peptides; prealbumin; topology; toxicity;     Show all 8 Subjects
Abstract:
... Alzheimer’s disease is associated with the deposition of the amyloid-β peptide (Aβ) into extracellular senile plaques in the brain. In vitro and in vivo observations have indicated that transthyretin (TTR) acts as an Aβ scavenger in the brain, but the mechanism has not been fully resolved. We have monitored the aggregation process of Aβ₄₀ by thioflavin T fluorescence, in the presence or absence of ...
DOI:
10.1021/acs.biomac.9b01475

3. A comparison of β-casein complexes and micelles as vehicles for trans-/cis-resveratrol

Author:
Cheng, Hao; Dong, Huanhuan; Wusigale,; Liang, Li
Source:
Food chemistry 2020 v.330 pp. 127209
ISSN:
0308-8146
Subject:
protective effect,   etc   ; aqueous solutions; beta-casein; bioactive compounds; cattle; cis-trans isomers; encapsulation; micelles; photoisomerization; polyphenols;     Show all 10 Subjects
Abstract:
... Bovine β-casein is an amphiphilic protein that exists as a monomer and self-organizes into micelles in aqueous solution. The protein has been used as natural vehicles for bioactives. Trans-resveratrol has received significant attention due to its vast health benefits and conversion to cis-isomer during processing and storage. However, cis-isomer has not yet gained as much attention as that of tran ...
DOI:
10.1016/j.foodchem.2020.127209

4. Accelerated shelf-life model of gluten-free rusks by using oxidation indices

Author:
Bravi, Elisabetta; Sileoni, Valeria; Perretti, Giuseppe; Marconi, Ombretta
Source:
Food chemistry 2020 v.326 pp. 126971
ISSN:
0308-8146
Subject:
protective effect,   etc   ; activation energy; antioxidants; gluten-free foods; models; oxidation; shelf life; temperature;     Show all 8 Subjects
Abstract:
... The demand for gluten-free products has been growing over the last few years as is the need to improve their quality. The objective of this research was to develop a shelf life prediction model of gluten-free rusks. To this aim, a kinetic study of the primary and secondary oxidative process was run and the kinetic parameters (rate constant, activation energy, and temperature quotient) were calcula ...
DOI:
10.1016/j.foodchem.2020.126971

5. Feasibility and mechanism of enhanced 17β-estradiol degradation by the nano Zero Valent Iron-citrate system

Author:
Yu, Weiwei; Yang, Shuo; Du, Banghao; Zhang, Zhi; Xie, Mingyuan; Chen, Yao; Zhao, Chenju; Chen, Xiangyu; Li, Qi
Source:
Journal of hazardous materials 2020 v.396 pp. 122657
ISSN:
0304-3894
Subject:
protective effect,   etc   ; citrates; cross-coupling reactions; estradiol; iron; nanomaterials; oxidation; pH; pollutants;     Show all 9 Subjects
Abstract:
... 17β-Estradiol (17β-E2) as a non-conventional pollutant with high damage, the effective removal of 17β-E2 had been studied wildly. In recent years, nano materials application enabled the rapid removal of 17β-E2. Nano zero valent iron (nZVI) as one of the most widely used nano materials could also be used to degrade 17β-E2. But, the degradation performance of nZVI was limited by oxidation and aggreg ...
DOI:
10.1016/j.jhazmat.2020.122657

6. Ginsenoside Rg1 protects against aging-induced renal interstitial fibrosis due to inhibition of tubular epithelial cells endoplasmic reticulum stress in SAMP8 mice

Author:
Ding, Shixin; Zhang, Han; Sun, Zhenghao; Han, Yuli; Li, Yan; Dong, Xianan; Yin, Yanyan; Li, Weiping; Li, Weizu
Source:
Journal of functional foods 2020 v.72 pp. 104049
ISSN:
1756-4646
Subject:
protective effect,   etc   ; apoptosis; endoplasmic reticulum; endoplasmic reticulum stress; epithelial cells; fibrosis; ginsenosides; kidney diseases; kidneys; mice;     Show all 10 Subjects
Abstract:
... Aging has become a primary cause of chronic kidney diseases, which ultimately progress to renal interstitial fibrosis. Endoplasmic reticulum (ER) stress has been reported to participate in tubular epithelial cells injury. Ginsenoside Rg1 may have protective effects on kidney aging. In this study, we investigated the tubular interstitial fibrosis and ER stress change in aged mice, and further obser ...
DOI:
10.1016/j.jff.2020.104049

7. Lycopene as a Natural Antioxidant Used to Prevent Human Health Disorders

Author:
Imran, Muhammad; Ghorat, Fereshteh; Ul-Haq, Iahtisham; Ur-Rehman, Habib; Aslam, Farhan; Heydari, Mojtaba; Shariati, Mohammad Ali; Okuskhanova, Eleonora; Yessimbekov, Zhanibek; Thiruvengadam, Muthu; Hashempur, Mohammad Hashem; Rebezov, Maksim
Source:
Antioxidants 2020 v.9 no.8
ISSN:
2076-3921
Subject:
protective effect,   etc   ; antioxidants; bone diseases; diabetes mellitus; dietary supplements; lycopene; neoplasms; reproductive disorders; tomatoes; toxicity;     Show all 10 Subjects
Abstract:
... Lycopene, belonging to the carotenoids, is a tetraterpene compound abundantly found in tomato and tomato-based products. It is fundamentally recognized as a potent antioxidant and a non-pro-vitamin A carotenoid. Lycopene has been found to be efficient in ameliorating cancer insurgences, diabetes mellitus, cardiac complications, oxidative stress-mediated malfunctions, inflammatory events, skin and ...
DOI:
10.3390/antiox9080706

8. Preferential degradation of leaf- vs. root-derived organic carbon in earthworm-affected soil

Author:
Angst, Gerrit; Angst, Šárka; Frouz, Jan; Peterse, Francien; Nierop, Klaas G.J.
Source:
Geoderma 2020 v.372 pp. 114391
ISSN:
0016-7061
Subject:
protective effect,   etc   ; cutin; earthworms; ecosystems; lipids; organic carbon; roots; soil; soil organic matter; stable isotopes; suberin;     Show all 11 Subjects
Abstract:
... Earthworms are integral parts of many ecosystems and may play a decisive role in determining whether soils function as carbon (C) sink or source. However, information on how earthworms affect the composition and stability of soil organic matter (SOM) is scarce. Particularly their effect on organic matter deriving from leaves and roots with distinct composition and, thus, susceptibility to decompos ...
DOI:
10.1016/j.geoderma.2020.114391

9. Endogenous oxytocin is essential for the buffering effects of pair housing against the increase in cocaine reward induced by social stress

Author:
Ferrer-Pérez, Carmen; Reguilón, Marina D.; Miñarro, José; Rodríguez-Arias, Marta
Source:
Physiology & behavior 2020 v.221 pp. 112913
ISSN:
0031-9384
Subject:
protective effect,   etc   ; antagonists; cocaine; drugs; males; mice; oxytocin; pair housing; psychosocial factors; social factors; therapeutics;     Show all 11 Subjects
Abstract:
... Social factors have a dual influence on addictive disorders. While social defeat stress in rodents increases the response to drug reward, positive social conditions, such as pair housing, increase stress resilience. The objective of the present study was to confirm whether oxytocin (OT) mediates this social buffering. To this end, male mice were housed in pairs and administered the OT receptor ant ...
DOI:
10.1016/j.physbeh.2020.112913

10. Influences of different carbohydrates as wall material on powder characteristics, encapsulation efficiency, stability and degradation kinetics of microencapsulated lutein by spray drying

Author:
Ding, Zhuang; Tao, Tao; Wang, Xiao; Prakash, Sangeeta; Zhao, Yanna; Han, Jun; Wang, Zhengping
Source:
International journal of food science & technology 2020 v.55 no.7 pp. 2872-2882
ISSN:
0950-5423
Subject:
protective effect,   etc   ; glass transition temperature; inulin; lutein; microencapsulation; powders; shelf life; spray drying;     Show all 8 Subjects
Abstract:
... In the present study, seven carbohydrates were selected as encapsulant for preparing lutein microencapsulated powders (LMPs). The surface morphology, physical properties, encapsulation efficiency, and thermo‐ and storage stability of LMPs were studied to determine the protective effects of different carbohydrates on microencapsulated lutein during spray drying and storage. Results on powder charac ...
DOI:
10.1111/ijfs.14544

11. Neuro-protection of Chlorogenic acid against Al-induced apoptosis in PC12 cells via modulation of Al metabolism and Akt/GSK-3β pathway

Author:
Cheng, Dai; Wang, Guangliang; Wang, Xuerui; Tang, Jinlei; Yu, Qianqian; Zhang, Xinyu; Wang, Shuo
Source:
Journal of functional foods 2020 v.70 pp. 103984
ISSN:
1756-4646
Subject:
protective effect,   etc   ; aluminum; aluminum chloride; apoptosis; chlorogenic acid; metabolism; neurotoxicity; polyphenols; signal transduction;     Show all 9 Subjects
Abstract:
... Dietary polyphenols showed good scavenging effects on the neurotoxicity of aluminum (Al). The aim of this study was to explore the mechanism of CGA on AlCl₃ in PC12 cells. Based on the protective effect of CGA on the apoptosis of PC12 cells induced by AlCl₃, we designed a scheme of intervention with CGA before, during and after AlCl₃ treatment. The results showed that the co-treatment of CGA and A ...
DOI:
10.1016/j.jff.2020.103984

12. Preparation, formation mechanism and in vitro dynamic digestion behavior of quercetin-loaded liposomes in hydrogels

Author:
Liu, Weilin; Kong, Youyu; Ye, Aiqian; Shen, Ping; Dong, Lu; Xu, Xiankang; Hou, Yingying; Wang, Yanping; Jin, Yangyi; Han, Jianzhong
Source:
Food hydrocolloids 2020 v.104 pp. 105743
ISSN:
0268-005X
Subject:
protective effect,   etc   ; chitosan; crosslinking; gelatin; hydrocolloids; hydrogels; hydrogen bonding; in vitro digestion; intestines; quercetin; texture;     Show all 11 Subjects
Abstract:
... Quercetin-loaded liposomes in hydrogels (lipogels) with different texture properties were fabricated, and their formation mechanism, along with the in vitro oral-gastrointestinal fate, were investigated. The hydrogels, composed of chitosan and gelatin, were cross-linked by ionic and covalent bonds, and interacted with liposomes by hydrogen bonds. More fragmentations were obtained from hard lipogel ...
DOI:
10.1016/j.foodhyd.2020.105743

13. Assessing the cyto-genotoxic potential of model zinc oxide nanoparticles in the presence of humic-acid-like-polycondensate (HALP) and the leonardite HA (LHA)

Author:
Efthimiou, Ioanna; Georgiou, Yiannis; Vlastos, Dimitris; Dailianis, Stefanos; Deligiannakis, Yiannis
Source:
The Science of the total environment 2020 v.721 pp. 137625
ISSN:
0048-9697
Subject:
protective effect,   etc   ; cell culture; cytokinesis; cytotoxicity; genotoxicity; humans; humic acids; lymphocytes; models; mutagens; nanoparticles; zinc oxide;     Show all 12 Subjects
Abstract:
... The present study investigates the potential cyto-genotoxic effects of model zinc oxide nanoparticles (ZnO NPs) on human lymphocytes, with and/or without humic acids (HAs). Two types of HAs were studied, a natural well-characterized leonardite HA (LHA) and its synthetic-model, a humic-acid-like-polycondensate (HALP). The Cytokinesis Block Micronucleus (CBMN) assay was applied in cell cultures trea ...
DOI:
10.1016/j.scitotenv.2020.137625

14. Alginate fiber toughened gels similar to skin intelligence as ionic sensors

Author:
Chen, Hao; Gao, Yang; Ren, Xiuyan; Gao, Guanghui
Source:
Carbohydrate polymers 2020 v.235 pp. 116018
ISSN:
0144-8617
Subject:
protective effect,   etc   ; artificial intelligence; humans; hydrogels; mechanical properties; polyvinyl alcohol; salts; sodium alginate;     Show all 8 Subjects
Abstract:
... The stretchable hydrogels provide potential alternatives to bionic skins. However, skin simulation remains seriously challenging due to its complex nature, including mechanical property, protective effect, and sensory capability. Herein, conductive gels toughened by sodium alginate fibers in oil-water system were developed for preparation of skin-like ionic sensors. The dynamic network was constru ...
DOI:
10.1016/j.carbpol.2020.116018

15. Computational Model to Unravel the Function of Amyloid-β Peptides in Contact with a Phospholipid Membrane

Author:
Huy Pham, Dinh Quoc; Krupa, Pawel; Nguyen, Hoang Linh; La Penna, Giovanni; Li, Mai Suan
Source:
TheJournal of physical chemistry 2020 v.124 no.16 pp. 3300-3314
ISSN:
1520-5207
Subject:
protective effect,   etc   ; amyloid beta-peptides; bioinformatics; cations; copper; magnesium; models; phospholipids; physical chemistry;     Show all 9 Subjects
Abstract:
... Divalent cations have a strong impact on the properties of phospholipid membranes, where amyloid-β peptides exert effects related to possible functional or pathological roles. In this work, we use an atomistic computational model of dimyristoyl-phosphatidylcholine (DMPC) membrane bilayers. We perturb this model with a simple model of divalent cations (Mg²⁺) and with a single amyloid-β (Aβ) peptide ...
DOI:
10.1021/acs.jpcb.0c00771

16. Protective effect of Epicatechin on APAP-induced acute liver injury of mice through anti-inflammation and apoptosis inhibition

Author:
Wu, Hao; Xie, Yanni; Xu, Yali; Hu, Zehua; Wan, Xing; Huang, Hancheng; Huang, Debin
Source:
Natural product research 2020 v.34 no.6 pp. 855-858
ISSN:
1478-6427
Subject:
protective effect,   etc   ; Euonymus alatus; acetaminophen; antineoplastic activity; antioxidants; apoptosis; epicatechin; liver diseases; mice;     Show all 9 Subjects
Abstract:
... Epicatechin (EC) is the most effective compound in Euonymus alatus (Thunb.)Sieb, and possesses a series of benefits, including anti-inflammatory, antioxidant, antiobesity and anticancer effects. In this study, we investigated the protective effects of EC in Acetaminophen(N-acetyl-p-aminophenol, APAP)-induced acute liver injury in C57BL/6J mice and explored the possible mechanisms involved in these ...
DOI:
10.1080/14786419.2018.1503261

17. Acclimation alters glyphosate temperature-dependent toxicity: Implications for risk assessment under climate change

Author:
Silva, Laís C.M.; Daam, Michiel A.; Gusmao, Felipe
Source:
Journal of hazardous materials 2020 v.385 pp. 121512
ISSN:
0304-3894
Subject:
protective effect,   etc   ; Ceriodaphnia; acclimation; climate change; glyphosate; heat tolerance; herbicide resistance; risk assessment; temperature; toxicity;     Show all 10 Subjects
Abstract:
... The evaluation of temperature-dependent chemical toxicity (TDCT) is imperative for future risk assessments of pesticides under global climate change scenarios. Few TDCT studies have so far considered the ability of organisms to acclimate to altered temperatures prior to pesticide exposure, although this may change their thermal tolerance range and hence their susceptibility to pesticide stress. Th ...
DOI:
10.1016/j.jhazmat.2019.121512

18. Identification of hydroxycinnamic acid derivatives of selected canadian and foreign commercial beer extracts and determination of their antioxidant properties

Author:
Rahman, Md Jiaur; Liang, Jingbang; Eskin, N.A. Michael; Eck, Peter; Thiyam-Holländer, Usha
Source:
Lebensmittel-Wissenschaft + [i.e. und] Technologie 2020 v.122 pp. 109021
ISSN:
0023-6438
Subject:
protective effect,   etc   ; antioxidant activity; antioxidants; beers; cations; ferulic acid; flavonoids; grains; high performance liquid chromatography; hops;     Show all 10 Subjects
Abstract:
... Phenolic compounds in beer are derived from grains and hops during processing and production. Thus, the total phenolic content (TPC) of beer extracts, from selected Canadian and foreign commercial, and laboratory produced beers were examined and ranged from 3.72 ± 0.23 to 13.73 ± 0.49 mg GAE/100 mL beer. The total flavonoid content (TFC) of the same beer extracts varied from 0.82 ± 0.02 to 5.28 ±  ...
DOI:
10.1016/j.lwt.2020.109021

19. Reconciling Hygiene and Cleanliness: A New Perspective from Human Microbiome

Author:
Gupta, Vipin; Kumar, Roshan; Sood, Utkarsh; Singhvi, Nirjara
Source:
Indian journal of microbiology 2020 v.60 no.1 pp. 37-44
ISSN:
0046-8991
Subject:
protective effect,   etc   ; aesthetics; disinfection; humans; hygiene; immune response; microbial communities; microbial load; microbiome;     Show all 9 Subjects
Abstract:
... The term hygiene is deeply rooted with the concept of maintaining sound health and alertness towards cleanliness, while “hygiene hypothesis” depicts the protective role of microbial community exposure in development of early immunity and initial allergic and aesthetic reactions. The tug-of-war has now been pushed toward the literal term “hygiene” over the “hygiene hypothesis” and has continued wit ...
DOI:
10.1007/s12088-019-00839-5
PubMed:
32089572
PubMed Central:
PMC7000587

20. Survival of Lactobacillus paracasei subsp. paracasei LBC 81 in Fermented Milk Enriched with Green Banana Pulp Under Acid Stress and in the Presence of Bile Salts

Author:
de Oliveira Vogado, Carolina; dos Santos Leandro, Eliana; de Alencar, Ernandes Rodrigues; Ginani, Verônica Cortez; Zandonadi, Renata Puppin
Source:
Probiotics and antimicrobial proteins 2020 v.12 no.1 pp. 320-324
ISSN:
1867-1306
Subject:
protective effect,   etc   ; Lactobacillus paracasei subsp. paracasei; bananas; bile salts; fermented milk; pH; pulp;     Show all 7 Subjects
Abstract:
... This study evaluated the in vitro effect of 3.0, 6.0, and 9.0% of green banana pulp (GBP) incorporation in fermented milk on the survival of Lactobacillus paracasei subsp. paracasei LBC 81 subjected to acid stress conditions and in the presence of bile salts. Tolerance to acid stress in pH 2.0 and in the presence of 0.30% of bile salts was evaluated right after the incorporation of the fermented m ...
DOI:
10.1007/s12602-019-09534-9