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1. Administration of a single dose of long-acting injectable progesterone formulation reduces the stress response to weaning in anestrous ewes

Author:
R. Ungerfeld; A. Freitas-de-Melo
Source:
Domestic animal endocrinology 2023 v.82 pp. 106753
ISSN:
0739-7240
Subject:
blood proteins,   etc   ; Corriedale; albumins; bioavailability; cortisol; farms; pastures; progesterone; stress response; sunflower oil;     Show all 10 Subjects
Abstract:
... High circulating progesterone concentrations decrease the responses to stressful situations in farm ruminants. We hypothesized that administering a single dose of long-acting progesterone formulation reduces the stress response of anestrous ewes to weaning. The aim of this study was to compare the behavioral, cortisol, and blood protein responses to weaning of anestrous ewes treated or not, with a ...
DOI:
10.1016/j.domaniend.2022.106753

2. Glycoproteomics analysis reveals differential site-specific N-glycosylation of donkey milk fat globule membrane protein during lactation

Author:
Boyuan Guan; Yuxia Chai; Xiakouna Amantai; Xiaoyu Liu; Xinping Chen; Xueyan Cao; Xiqing Yue; Biao Liu
Source:
Food chemistry 2023 v.402 pp. 134266
ISSN:
0308-8146
Subject:
membrane proteins,   etc   ; ass milk; asses; colostrum; food chemistry; glycoproteins; glycoproteomics; lactation; mannosylation; milk; milk fat;     Show all 11 Subjects
Abstract:
... N-glycosylation is a prevalent and complex post-translational modification of milk proteins with significant biological importance. However, the systematic characterisation of donkey milk fat globule membrane (MFGM) N-glycoproteins remains largely ill-defined. Here, 1443 intact N-glycopeptides from 336 MFGM glycoproteins in donkey colostrum (DC) and 489 intact N-glycopeptides from 86 MFGM glycopro ...
DOI:
10.1016/j.foodchem.2022.134266

3. Low temperature microfiltration of skim milk: Impact of membrane type, configuration and concentration factor on serum protein permeation efficiency

Author:
Surabhi Subhir; Paul L.H. McSweeney; Mark A. Fenelon; John T. Tobin
Source:
International dairy journal 2023 v.137 pp. 105500
ISSN:
0958-6946
Subject:
blood proteins,   etc   ; blood serum; crude protein; energy; microfiltration; molecular weight; permeability; polymers; porosity; skim milk; temperature;     Show all 11 Subjects
Abstract:
... Protein transmission, permeate flux and energy consumption during MF of skim milk was evaluated at 7 °C using two discrete 800 kDa polymeric MF membranes. Filtration trials determined optimum process parameters (i.e., transmembrane pressure and volume concentration factor) and membrane configuration (in-series or in-parallel) to maximise serum protein permeation. This study demonstrated that a com ...
DOI:
10.1016/j.idairyj.2022.105500

4. Evaluation and selection of yeasts as potential aroma enhancers for the production of dry-cured ham

Author:
Xiaohui Gong; Ruifang Mi; Xi Chen; Qiujin Zhu; Suyue Xiong; Biao Qi; Shouwei Wang
Source:
Food science and human wellness 2023 v.12 no.1 pp. 324-335
ISSN:
2213-4530
Subject:
milk proteins,   etc   ; Candida zeylanoides; Debaryomyces hansenii; Yarrowia; cured meats; flavor; ham; humans; meat protein; odors; proteolysis; tributyrin; yeasts;     Show all 13 Subjects
Abstract:
... Yeasts play a critical role in the flavor formation of dry-cured ham. In this study, 41 yeast isolates from the dry-cured ham at different processing stages were evaluated for their technological properties. Debaryomyces hansenii was the most dominant yeast and has been detected at each phase of dry-cured ham, followed by Candida zeylanoides which was mainly detected in salting phase. Yarrowia bub ...
DOI:
10.1016/j.fshw.2022.07.022

5. In silico analysis of upstream variants in Brazilian patients with Familial hypercholesterolemia

Author:
Jéssica Nayara Góes de Araújo; Victor Fernandes de Oliveira; Jéssica Bassani Borges; Carolina Dagli-Hernandez; Elisangela da Silva Rodrigues Marçal; Renata Caroline Costa de Freitas; Gisele Medeiros Bastos; Rodrigo Marques Gonçalves; André Arpad Faludi; Cinthia Elim Jannes; Alexandre da Costa Pereira; Rosario Dominguez Crespo Hirata; Mario Hiroyuki Hirata; André Ducati Luchessi; Vivian Nogueira Silbiger
Source:
Gene 2023 v.849 pp. 146908
ISSN:
0378-1119
Subject:
repressor proteins,   etc   ; chronic exposure; computer simulation; death; genes; genetic disorders; hypercholesterolemia; low density lipoprotein cholesterol; phenotype; prediction; risk;     Show all 11 Subjects
Abstract:
... Familial hypercholesterolemia (FH) is a prevalent autosomal genetic disease associated with increased risk of early cardiovascular events and death due to chronic exposure to very high levels of low-density lipoprotein cholesterol (LDL-c). Pathogenic variants in the coding regions of LDLR, APOB and PCSK9 account for most FH cases, and variants in non-coding regions maybe involved in FH as well. Va ...
DOI:
10.1016/j.gene.2022.146908

6. Food peptides as inducers of CCK and GLP-1 secretion and GPCRs involved in enteroendocrine cell signalling

Author:
Marta Santos-Hernández; Santiaga María Vivanco-Maroto; Beatriz Miralles; Isidra Recio
Source:
Food chemistry 2023 v.402 pp. 134225
ISSN:
0308-8146
Subject:
G-proteins,   etc   ; calcium receptors; cell lines; cholecystokinin; digestion; food chemistry; gastrointestinal system; glucagon-like peptide 1; hormone secretion; lysozyme;     Show all 10 Subjects
Abstract:
... The strong effect of protein digestion products on gastrointestinal-released hormones is recognised. However, little is known about the specific peptide sequences able to induce gastrointestinal hormone secretion and the receptors involved. Our objective was to identify peptides able to induce the secretion of cholecystokinin (CCK) and glucagon like peptide-1 (GLP-1) in the enteroendocrine cell li ...
DOI:
10.1016/j.foodchem.2022.134225

7. Smartphone recognition-based immune microparticles for rapid on-site visual data-sharing detection of Newcastle disease virus

Author:
Shenjunjie Lu; Binglin Ma; Haoran Zhou; Yayang Li; Zhihao Qiao; Tong Xiao; Husheng Li; Baijie Wang; Meihui Cui; Shufang Zhang; Jin Chang; Taofeng Du; Jing Liu; Hanjie Wang
Source:
Talanta 2023 v.252 pp. 123845
ISSN:
0039-9140
Subject:
nucleocapsid proteins,   etc   ; Avian orthoavulavirus 1; antibodies; blood serum; color; human resources; humans; hydrogels; image analysis; industry; mobile telephones; viruses;     Show all 12 Subjects
Abstract:
... Since the last century, animal viruses have posed great threats to the health of humans and the farming industry. Therefore, virus control is of great urgency, and regular, timely, and accurate detection is essential to it. Here, we designed a rapid on-site visual data-sharing detection method for the Newcastle disease virus with smartphone recognition-based immune microparticles. The detection me ...
DOI:
10.1016/j.talanta.2022.123845

8. RPS6 transcriptional modulation in neural tissues of Nauphoeta cinerea during streptozotocin-associated sugar metabolism impairment.

Author:
Olawande C. Olagoke; Ana L.A. Segatto; Blessing A. Afolabi; Daniel Ardisson-Araujo; Michael Aschner; João B.T. Rocha
Source:
Comparative biochemistry and physiology 2023 v.263 pp. 110785
ISSN:
1096-4959
Subject:
ribosomal proteins,   etc   ; Nauphoeta cinerea; biomedical research; brain; glucose; hyperglycemia; insects; metabolism; non-specific serine/threonine protein kinase; peptides; sequence analysis; streptozotocin; transcription (genetics);     Show all 13 Subjects
Abstract:
... The use of insects to model molecular events that characterize degenerative conditions was originally met with scepticism. However, the discovery of insect insulin-like peptides in the 1970's and the demonstration of evolutionary conservation of insulin-related signalling from insects to mammals have highlighted the importance and reduced cost of insect models in biomedical research. Here, we expa ...
DOI:
10.1016/j.cbpb.2022.110785

9. Characterization of pIgR and its association with resistance to iridovirus in Asian seabass

Author:
Yi Xuan Tay; Yepin Yu; Zituo Yang; Le Wang; Fei Sun; Gen Hua Yue
Source:
Aquaculture 2023 v.562 pp. 738783
ISSN:
0044-8486
Subject:
coat proteins,   etc   ; Lates calcarifer; Singapore grouper iridovirus; aquaculture; cell lines; disease resistance; eyes; fingerlings; genes; genotyping; heart; immunoglobulins; intestines; kidneys; mucosal immunity; polymers;     Show all 16 Subjects
Abstract:
... The improvement of disease resistance is vital in aquaculture as diseases are one of the serious threats to successful aquaculture. Understanding of molecular mechanisms underlying disease resistance is important in improving resistance against diseases. The pIgR (polymeric immunoglobulin receptor) gene plays an important role in the mucosal immunity of fish. However, not much is known about its r ...
DOI:
10.1016/j.aquaculture.2022.738783

10. Goat milk proteins enriched with Agaricus blazei Murrill ss. Heinem extracts: Electrophoretic, FTIR, DLS and microstructure characterization

Author:
Dušanka A. Popović Minić; Danijel D. Milinčić; Stefan Kolašinac; Vladislav Rac; Jovana Petrović; Marina Soković; Nebojša Banjac; Jelena Lađarević; Bojana B. Vidović; Aleksandar Ž. Kostić; Vladimir B. Pavlović; Mirjana B. Pešić
Source:
Food chemistry 2023 v.402 pp. 134299
ISSN:
0308-8146
Subject:
milk proteins,   etc   ; Agaricus subrufescens; Fourier transform infrared spectroscopy; electron microscopy; electrophoresis; food chemistry; glycosides; goat milk; hydrogen; hydrophobicity; microstructure; milk; particle size; polypeptides; polysaccharides; proteolysis;     Show all 16 Subjects
Abstract:
... This study aimed to characterize mixtures of goat milk proteins and Agaricus blazei Murrill (ABM) extracts (aqueous, AE and polysaccharides, PE). The mixtures showed stable particles with ζ-potential more negative than −41.1 mV. The addition of AMB extracts to goat milk did not result in a significant particle size change, whereas their addition to heated goat milk significantly increased mean par ...
DOI:
10.1016/j.foodchem.2022.134299

11. Celastrus orbiculatus Thunb. extract inhibits EMT and metastasis of gastric cancer by regulating actin cytoskeleton remodeling

Author:
Haibo Wang; YuanYuan Luo; Shiya Ou; Tengyang Ni; Zewen Chu; Xinyi Feng; Xiaojun Dai; Xiaochun Zhang; Yanqing Liu
Source:
Journal of ethnopharmacology 2023 v.301 pp. 115737
ISSN:
0378-8741
Subject:
regulatory proteins,   etc   ; Celastrus orbiculatus; Oriental traditional medicine; Western blotting; actin; analgesics; animals; cell movement; medicinal plants; metalloproteinases; metastasis; microfilaments; neoplasm cells; protein degradation; stomach neoplasms; China;     Show all 16 Subjects
Abstract:
... The traditional Chinese medicine herb Celastrus orbiculatus Thunb. is an important folk medicinal plant in China that has been used as an anti-inflammatory, antitumor, and analgesic in various diseases. Recent years, many studies have reported the significant effects of Celastrus orbiculatus Thunb. extract (COE) on gastric cancer. However, the specific mechanism by which COE regulates gastric canc ...
DOI:
10.1016/j.jep.2022.115737

12. Effect of sulfamethazine on the horizontal transfer of plasmid-mediated antibiotic resistance genes and its mechanism of action

Author:
Xiaojing Yan; Wenwen Liu; Shengfang Wen; Lanjun Wang; Lusheng Zhu; Jun Wang; Young Mo Kim; Jinhua Wang
Source:
Journal of environmental sciences (China) 2023 v.127 pp. 399-409
ISSN:
1001-0742
Subject:
outer membrane proteins,   etc   ; Escherichia coli; antibacterial properties; antibiotic resistance; cell membranes; gene expression; horizontal gene transfer; mechanism of action; oxidative stress; permeability; plasmids; pollutants; sulfamethazine; China;     Show all 14 Subjects
Abstract:
... As a new type of environmental pollutant, antibiotic resistance genes (ARGs) pose a huge challenge to global health. Horizontal gene transfer (HGT) represents an important route for the spread of ARGs. The widespread use of sulfamethazine (SM2) as a broad-spectrum bacteriostatic agent leads to high residual levels in the environment, thereby increasing the spread of ARGs. Therefore, we chose to st ...
DOI:
10.1016/j.jes.2022.06.014

13. Olfaction and gustatory senses promote feeding through different pathways in yellowtail, Seriola quinqueradiata

Author:
Ayaka Senzui; Haruhisa Fukada
Source:
Aquaculture 2023 v.562 pp. 738814
ISSN:
0044-8486
Subject:
plant proteins,   etc   ; Seriola quinqueradiata; alanine; appetite; aquaculture; carnivores; cerebellum; feed intake; fish; fish meal; food intake; gene expression; hypothalamus; neuropeptide Y; odors; olfactory bulb; proline; smell; taste;     Show all 19 Subjects
Abstract:
... For sustainable aquaculture, the replacement of dietary fishmeal with plant protein is becoming more common because fishmeal resources are limited. However, in the case of carnivorous fish such as yellowtail (Seriola quinqueradiata), reducing the dietary fishmeal level often causes low feed intake. Improving feed intake is important in the use of a non- and low-fishmeal diet. However, little is kn ...
DOI:
10.1016/j.aquaculture.2022.738814

14. Pomegranate (Punica granatum) peel extract supplementation in diet influences growth performance, haemato-immunological responses and cytokine expression in pathogen- aggravated Labeo rohita fingerlings

Author:
Sanjay Kumar Gupta; Akruti Gupta; Biplab Sarkar; Rajan Gupta; Madan Kumar; Aditi Kumari; Md. Javed Foysal
Source:
Aquaculture 2023 v.562 pp. 738823
ISSN:
0044-8486
Subject:
blood proteins,   etc   ; Aeromonas hydrophila; Labeo rohita; Punica granatum; aquaculture; dietary supplements; disease resistance; fish; gene expression; globulins; growth performance; innate immunity; interleukin-10; kidneys; liver; lysozyme; pomegranates; respiratory burst; specific growth rate;     Show all 19 Subjects
Abstract:
... Pomegranate peel extract (PPE) has been widely identified as a rich source of therapeutically active phyto-compounds, known for their beneficial effects in aquaculturable species. In this context, a 60-day feeding trial was carried out to evaluate the effect of supplementation of pomegranate peel extract (PPE) on growth performance, haemato-immunological responses and cytokine gene expression in L ...
DOI:
10.1016/j.aquaculture.2022.738823

15. Intermittent induction of LEA peptide by lactose enhances the expression of insecticidal proteins in Bacillus thuringiensis

Author:
Mahmuda Akthar; Tomoko Shimokawa; Yinghan Wu; Taichi Arita; Kazuhiro Mizuta; Yuria Isono; Minoru Maeda; Shinya Ikeno
Source:
FEBS Open Bio 2022 v.12 no.8 pp. 1534-1541
ISSN:
2211-5463
Subject:
bacterial proteins; recombinant proteins,   etc   ; Bacillus thuringiensis; embryogenesis; lactose; peptides; protein synthesis;     Show all 7 Subjects
Abstract:
... Cry toxins from Bacillus thuringiensis (Bt) have been extensively applied in agriculture to substitute the use of chemical insecticides. We have previously reported the use of a coexpression system in which late embryogenesis abundant (LEA) peptides under the control of the lac promoter increase the expression of insecticidal proteins in Bt. The use of lactose to induce the expression of LEA pepti ...
DOI:
10.1002/2211-5463.13448

16. Graph-theoretic constraints on vesicle traffic networks

Author:
Somya Mani; Kesav Krishnan; Mukund Thattai
Source:
Journal of biosciences 2022 v.47 no.1 pp. 11
ISSN:
0250-5991
Subject:
SNARE proteins; transmembrane proteins,   etc   ; eukaryotic cells; graphs; journals; physiological transport; travel;     Show all 7 Subjects
Abstract:
... Eukaryotic cells use small membrane-enclosed vesicles to transport molecular cargo between intracellular compartments. Interactions between molecules on vesicles and compartments determine the source and target compartment of each vesicle type. The set of compartment and vesicle types in a cell define the nodes and edges of a transport graph known as the vesicle traffic network. The transmembrane ...
DOI:
10.1007/s12038-021-00252-5

17. Upstream of N-Ras (Unr/CSDE1) Interacts with NCp7 and Gag, Modulating HIV-1 IRES-Mediated Translation Initiation

Author:
Nedal Taha; Sarwat Zgheib; Kamal Kant Sharma; Nicolas Humbert; Emmanuel Boutant; Pascal Didier; Yves Mély; Eleonore Real
Source:
Viruses 2022 v.14 no.8 pp. -
ISSN:
1999-4915
Subject:
RNA-binding proteins; nucleocapsid proteins,   etc   ; Human immunodeficiency virus 1; luciferase; precipitin tests;     Show all 5 Subjects
Abstract:
... The Human Immunodeficiency Virus-1 (HIV-1) nucleocapsid protein (NC) as a mature protein or as a domain of the Gag precursor plays important roles in the early and late phases of the infection. To better understand its roles, we searched for new cellular partners and identified the RNA-binding protein Unr/CSDE1, Upstream of N-ras, whose interaction with Gag and NCp7 was confirmed by co-immunopreci ...
DOI:
10.3390/v14081798

18. Structural advances in sterol-sensing domain-containing proteins

Author:
Xuelan Wu; Renhong Yan; Pingping Cao; Hongwu Qian; Nieng Yan
Source:
Trends in biochemical sciences 2022 v.47 no.4 pp. 289-300
ISSN:
0968-0004
Subject:
regulatory proteins; transport proteins,   etc   ; behavior change; cell membranes; cholesterol metabolism; physiological transport; sterols;     Show all 7 Subjects
Abstract:
... The sterol-sensing domain (SSD) is present in several membrane proteins that function in cholesterol metabolism, transport, and signaling. Recent progress in structural studies of SSD-containing proteins, such as sterol regulatory element-binding protein (SREBP)-cleavage activating protein (Scap), Patched, Niemann-Pick disease type C1 (NPC1), and related proteins, reveals a conserved core that is ...
DOI:
10.1016/j.tibs.2021.12.005

19. Annexins A1 and A2 are recruited to larger lysosomal injuries independently of ESCRTs to promote repair

Author:
Willa Wen‐You Yim; Hayashi Yamamoto; Noboru Mizushima
Source:
FEBS letters 2022 v.596 no.8 pp. 991-1003
ISSN:
0014-5793
Subject:
membrane proteins,   etc   ; calcium; lysosomes;     Show all 3 Subjects
Abstract:
... Damaged lysosomes can be repaired by calcium release‐dependent recruitment of the ESCRT machinery. However, the involvement of annexins, another group of calcium‐responding membrane repair proteins, has not been fully addressed. Here, we show that although all ubiquitously expressed annexins (ANXA1, A2, A4, A5, A6, A7, and A11) localize to damaged lysosomes, only ANXA1 and ANXA2 are important for ...
DOI:
10.1002/1873-3468.14329

20. Travel light: Essential packing for membrane proteins with an active lifestyle

Author:
Nicolai Tidemand Johansen; Frederik Grønbæk Tidemand; Martin Cramer Pedersen; Lise Arleth
Source:
Biochimie 2022 pp. -
ISSN:
0300-9084
Subject:
membrane proteins,   etc   ; lifestyle; travel;     Show all 3 Subjects
Abstract:
... We review the considerable progress during the recent decade in the endeavours of designing, optimising, and utilising carrier particle systems for structural and functional studies of membrane proteins in near-native environments. New and improved systems are constantly emerging, novel studies push the perceived limits of a given carrier system, and specific carrier systems consolidate and entren ...
DOI:
10.1016/j.biochi.2022.07.014