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1. Dissection of Moringa oleifera leaf metabolome in context of its different extracts, origin and in relationship to its biological effects as analysed using molecular networking and chemometrics

Author:
Zeinab T. Abdel Shakour; Radwa H. El-Akad; Abdelsamed I. Elshamy; Abd El-Nasser G. El Gendy; Ludger A. Wessjohann; Mohamed A. Farag
Source:
Food chemistry 2023 v.399 pp. 133948
ISSN:
0308-8146
Subject:
quercetin,   etc   ; Moringa oleifera; amides; carotenoids; chemometrics; dietary supplements; dissection; food chemistry; glucosinolates; kaempferol; leaves; metabolites; metabolome; nutritive value; peptides; polyphenols; solvents;     Show all 17 Subjects
Abstract:
... M. oleifera known as “miracle tree” is increasingly used in nutraceuticals for the reported health effects and nutritional value of its leaves. This study presents the first metabolome profiling of M. oleifera leaves of African origin using different solvent polarities via HR-UPLC/MS based molecular networking followed by multivariate data analyses for samples classification. 119 Chemicals were ch ...
DOI:
10.1016/j.foodchem.2022.133948

2. Development and characterization of active packaging films based on chitosan, plasticizer, and quercetin for repassed oil storage

Author:
Ewelina Jakubowska; Magdalena Gierszewska; Aleksandra Szydłowska-Czerniak; Jacek Nowaczyk; Ewa Olewnik-Kruszkowska
Source:
Food chemistry 2023 v.399 pp. 133934
ISSN:
0308-8146
Subject:
quercetin,   etc   ; antioxidant activity; antioxidants; chitosan; choline chloride; citric acid; food chemistry; lipid peroxidation; modulus of elasticity; oxidation; plasticizers; rapeseed; solvents; tensile strength;     Show all 14 Subjects
Abstract:
... Novel chitosan (Ch) films containing choline chloride and citric acid mixture as plasticizer (deep eutectic solvent, DES) and different amounts of quercetin (QUE) as antioxidant additive were prepared. Physicochemical and mechanical characteristics of the developed Ch/DES/QUE films were studied using FTIR, SEM, and AFM techniques. FTIR spectra revealed the possible interactions between all the com ...
DOI:
10.1016/j.foodchem.2022.133934

3. Discovery of a novel phosphotransferase from Bacillus subtilis that phosphorylates a broad spectrum of flavonoids

Author:
Chen Hsu; Hsin-Ya Tsai; Chi-Fon Chang; Chien-Chih Yang; Nan-Wei Su
Source:
Food chemistry 2023 v.400 pp. 134001
ISSN:
0308-8146
Subject:
quercetin,   etc   ; Bacillus subtilis; apigenin; bioavailability; biosynthesis; daidzein; dietary supplements; enzymes; food chemistry; genistein; hesperetin; kaempferol; luteolin; moieties; naringenin; orthophosphates; phosphorylation; regioselectivity; solubility;     Show all 19 Subjects
Abstract:
... Flavonoids are associated with health benefits, but most of them have poor oral bioavailability due to their extremely low aqueous solubility. Flavonoid O-phosphorylation suggests a potent modification to solve the problems. Here, we isolated, identified and characterized an unprecedented phosphotransferase, flavonoid phosphate synthetase (BsFPS), from B. subtilis. The enzyme catalyzes the ATP-dep ...
DOI:
10.1016/j.foodchem.2022.134001

4. The effect of quercetin mediated photodynamic inactivation on apple juice properties at different temperature and its bactericidal mechanism

Author:
In-Hwan Lee; Eun-Rae Cho; Dong-Hyun Kang
Source:
Food control 2023 v.144 pp. 109362
ISSN:
0956-7135
Subject:
quercetin,   etc   ; Escherichia coli O157; Listeria monocytogenes; adverse effects; ambient temperature; apple juice; blue light; enzyme activity; food safety; membrane potential; succinate dehydrogenase (quinone);     Show all 11 Subjects
Abstract:
... The inactivation efficacy, mechanism, and effect on apple juice properties of 405 nm blue light combined with quercetin in apple juice were investigated. At 60 J/cm², Listeria monocytogenes and Escherichia coli O157:H7 cells experienced more than 5 log reduction at room temperature. The depolarized membrane potential and loss of succinate dehydrogenase enzyme activity showed that the membrane and ...
DOI:
10.1016/j.foodcont.2022.109362

5. Control of dry rot and resistance induction in potato tubers against Fusarium sambucinum using red onion peel extract

Author:
Elsherbiny A. Elsherbiny; Dawood H. Dawood; Mahmoud F. Elsebai; Amira Mira; Mohamed A. Taher
Source:
Postharvest biology and technology 2023 v.195 pp. 112119
ISSN:
0925-5214
Subject:
quercetin,   etc   ; Fusarium sambucinum; catalase; catechol oxidase; ferulic acid; fungal growth; glucosides; isorhamnetin; kaempferol; methanol; onion peels; peroxidase; phenylalanine ammonia-lyase; potatoes; rutin; spore germination; storage time;     Show all 17 Subjects
Abstract:
... The efficacy of red onion peel methanol extract to prevent dry rot in potato tubers caused by Fusarium sambucinum was investigated. At 20 mg mL⁻¹, the methanol extract caused a great decrease in the fungal growth and spore germination by 86.3 %, and 91.2 %, respectively. Also, the dry rot control efficacy in potato slices inoculated with F. sambucinum reached 91.8 % at the same concentration. The ...
DOI:
10.1016/j.postharvbio.2022.112119

6. Study of effects of dietary quercetin (Que) on growth performance and disease resistance mechanism of Litopenaeus vannamei

Author:
Zhifei Chen; Depeng Fan; Luqing Pan; Chen Su; Yanjun Ding; Mingxiang Lu
Source:
Aquaculture 2023 v.563 pp. 738887
ISSN:
0044-8486
Subject:
quercetin,   etc   ; Litopenaeus vannamei; White spot syndrome virus; antibacterial properties; antioxidant activity; aquaculture; catalase; crude fat; disease resistance; gene expression; glutathione; glutathione peroxidase; growth performance; hemocytes; immune response; intestinal microorganisms; mortality; phagocytosis; shrimp; superoxide dismutase;     Show all 20 Subjects
Abstract:
... The purpose of this study was to evaluate effects of dietary quercetin (Que) on growth performance and disease resistance mechanism of Litopenaeus vannamei. Shrimp were randomly divided into 4 groups, with 3 replicants in each group and 70 shrimp in each replicants. The contents of Que. in the four groups were 0, 0.25, 0.5 and 1 g kg⁻¹, respectively. Samples were taken after 56 days, followed by a ...
DOI:
10.1016/j.aquaculture.2022.738887

7. Integrated serum pharmacochemistry and network pharmacology analyses reveal the bioactive metabolites and potential functional mechanism of ground cherry (Physalis pruinosa L.) in treatment of type 2 diabetes mellitus in rats

Author:
Asmaa Mahana; Hala M. Hammoda; Asmaa A. Khalifa; Samar S. Elblehi; Fathallah M. Harraz; Eman Shawky
Source:
Journal of ethnopharmacology 2023 v.300 pp. 115750
ISSN:
0378-8741
Subject:
quercetin,   etc   ; Physalis pruinosa; atherosclerosis; blood serum; calyx; cherries; gene ontology; genome; glucose; glycemic effect; high fat diet; histopathology; immunoblotting; insulin; lipid metabolism; lipids; mechanism of action; metabolites; models; noninsulin-dependent diabetes mellitus; pharmacology; rats; streptozotocin; traditional medicine;     Show all 24 Subjects
Abstract:
... Different Physalis plants have been widely employed in traditional medicine for management of diabetes mellitus. Previous studies with respect to the in vivo antidiabetic activity of Physalis plants illustrated that they improved glucose and lipid metabolism in streptozotocin (STZ) -induced diabetic rats yet the mechanism of action of bioactive constituents of the different organs of Physalis plan ...
DOI:
10.1016/j.jep.2022.115750

8. Evaluation of the anti-browning effect of quercetin on cut potatoes during storage

Author:
Cemal Kasnak
Source:
Food packaging and shelf life 2022 v.31 pp. 100816
ISSN:
2214-2894
Subject:
quercetin,   etc   ; color; shelf life;     Show all 3 Subjects
Abstract:
... The effects of quercetin treatment on enzymatic and oxidative activity, color quality and phenolic compound content of fresh-cut potatoes were investigated. To determine the effective anti-browning amount of quercetin, color change with storage was examined by making a preliminary experiment. At the end of the preliminary trial, it was determined that 25 mg/100 mL quercetin treatment kept the brow ...
DOI:
10.1016/j.fpsl.2022.100816

9. UHPLC-PDA-ESI-MS profile of phenolic compounds in the aerial parts of Cuphea ingrata Cham. & Schltdl.

Author:
Danuta Sobolewska; Aleksandra Owczarek; Monika Olszewska; Niraldo Paulino; Irma Podolak; Paweł Paśko; Dagmara Wróbel-Biedrawa; Klaudia Michalska
Source:
Natural product research 2022 v.36 no.14 pp. 3721-3725
ISSN:
1478-6427
Subject:
quercetin,   etc   ; Cuphea carthagenensis; chemotaxonomy; research; sulfates;     Show all 5 Subjects
Abstract:
... The purpose of the current study was a qualitative UHPLC-PDA-ESI-MS analysis of phenolic compounds in the aerial parts of Cuphea ingrata, which led to detection of over sixty constituents: tannins, flavonoids, phenolic acids and their derivatives. The presence of oenothein B-type macrocyclic dimeric ellagitannins seems to be of particular importance. Quercetin sulfate, that has been previously ide ...
DOI:
10.1080/14786419.2020.1868463

10. Synergistic growth-inhibition effect of quercetin and N-Acetyl-L-cysteine against HepG2 cells relying on the improvement of quercetin stability

Author:
Yijun Yao; Wenfei Xiong; Lin Chen; Xingrong Ju; Lifeng Wang
Source:
Food chemistry 2022 v.374 pp. 131729
ISSN:
0308-8146
Subject:
quercetin,   etc   ; acetylcysteine; antioxidants; culture media; food chemistry;     Show all 5 Subjects
Abstract:
... In this study, N-Acetyl-l-cysteine (NAC) as a widely-used antioxidant was first applied to improve the stability of Que in medium. The stability of Que in medium was analyzed, and the growth-inhibition effect of Que and NAC against HepG2 cells was estimated. The results showed NAC could significantly improve the stability of Que in medium (more than 80%), while Que alone in medium was totally degr ...
DOI:
10.1016/j.foodchem.2021.131729

11. Attempts to Create Products with Increased Health-Promoting Potential Starting with Pinot Noir Pomace: Investigations on the Process and Its Methods

Author:
Stephen Lo; Lisa I. Pilkington; David Barker; Bruno Fedrizzi
Source:
Foods 2022 v.11 no.14 pp. -
ISSN:
2304-8158
Subject:
quercetin,   etc   ; derivatization; grapes; health promotion; polyphenols; pomace; solvents;     Show all 7 Subjects
Abstract:
... A process for using grape (Pinot noir) pomace to produce products with improved health-promoting effects was investigated. This process integrated a solid–liquid extraction (SLE) method and a method to acylate the polyphenolics in the extract. This report describes and discusses the methods used, including the rationale and considerations behind them, and the results obtained. The study begins wit ...
DOI:
10.3390/foods11141999

12. Dual channel sensor array based on ZnCdSe QDs – KMnO4: An effective tool for analysis of catechins and green teas

Author:
Yao Fan; Siying Che; Lei Zhang; Chunsong Zhou; Haiyan Fu; Yuanbin She
Source:
Food research international 2022 v.160 pp. 111734
ISSN:
0963-9969
Subject:
quercetin,   etc   ; flavanols; fluorescence; food research; models; potassium permanganate;     Show all 6 Subjects
Abstract:
... A novel dual-channel sensor array based on the “off” and “off–on” phenomenon of ZnCdSe quantum dots (QDs) - KMnO₄ system was established for the effective distinguish of 30 green teas with various species, grades and origins. Starting from optimization of QDs for the construction of the sensing system, their sensitivity and selectivity performances towards 10 representative green teas were tested ...
DOI:
10.1016/j.foodres.2022.111734

13. A flavonoid, quercetin, is capable of enhancing long-term memory formation if encountered at different times in the learning, memory formation, and memory recall continuum

Author:
Veronica Rivi; Anuradha Batabyal; Cristina Benatti; Johanna MC Blom; Fabio Tascedda; Ken Lukowiak
Source:
Journal of comparative physiology 2022 v.208 no.2 pp. 253-265
ISSN:
0340-7594
Subject:
quercetin,   etc   ; Lymnaea stagnalis; cognition; diet; memory; physiology; snails;     Show all 7 Subjects
Abstract:
... A major extrinsic factor influencing memory and neuro-cognitive performances across taxa is diet. Studies from vertebrates have shown the effects of a flavonoid rich diet on cognitive performance, but the mechanism underlying this action is still poorly understood. A common and abundant flavonoid present in numerous food substances is quercetin (Q). The present study provides the first support for ...
DOI:
10.1007/s00359-021-01522-1

14. Ficus spp. fruits: Bioactive compounds and chemical, biological and pharmacological properties

Author:
Josias Martins dos Anjos Cruz; Renilto Frota Corrêa; Carlos Victor Lamarão; Valdely Ferreira Kinupp; Edgar Aparecido Sanches; Pedro Henrique Campelo; Jaqueline de Araújo Bezerra
Source:
Food research international 2022 v.152 pp. 110928
ISSN:
0963-9969
Subject:
quercetin,   etc   ; Ficus; antioxidants; cyanidin; food industry; food research;     Show all 6 Subjects
Abstract:
... The aim of this review was to compile the main reports over the last 5 years concerning the Ficus spp. fruits (Moraceae family) based on chemistry, properties, and applications as products. About 30 Ficus spp. fruits were reported focusing on their chemical composition rich in phenolic acids such as gallic, caffeic and chlorogenic acids, as well as quercetin and cyanidin derivatives. The fruits fr ...
DOI:
10.1016/j.foodres.2021.110928

15. Flavonoids and anthocyanins from the leaves of the Pride of Burma (Amherstia nobilis)

Author:
Tsukasa Iwashina; Nobuyuki Tanaka; Mu Mu Aung; Hari Prasad Devkota; Takayuki Mizuno
Source:
Biochemical systematics and ecology 2022 v.101 pp. 104391
ISSN:
0305-1978
Subject:
quercetin,   etc   ; Amherstia; anthocyanins; chemotaxonomy; cyanidin; ecology; luteolin; phylogeny; Myanmar;     Show all 9 Subjects
Abstract:
... Three flavonols, two flavones and six C-glycosylflavones were isolated from the mature leaves of the Pride of Burma (Amherstia nobilis) endemic to Myanmar. In addition, three anthocyanins were isolated from the dark red sprouting leaves of the species, together with the flavonoids in the mature leaves. They were identified as quercetin 3-O-glucoside (1), 3′-O-glucoside (2) and 3-O-xyloside (3) (fl ...
DOI:
10.1016/j.bse.2022.104391

16. Impact of the Flavonoid Quercetin on β-Amyloid Aggregation Revealed by Intrinsic Fluorescence

Author:
Abeer Alghamdi; David J.S. Birch; Vladislav Vyshemirsky; Olaf J. Rolinski
Source:
Journal of physical chemistry 2022 v.126 no.38 pp. 7229-7237
ISSN:
1520-5207
Subject:
quercetin,   etc   ; fluorescence; fluorescent dyes; human nutrition; physical chemistry; tyrosine;     Show all 6 Subjects
Abstract:
... We report the effects of quercetin, a flavonoid present in the human diet, on early stage beta-amyloid (Aβ) aggregation, a seminal event in Alzheimer’s disease. Molecular level changes in Aβ arrangements are monitored by time-resolved emission spectral (TRES) measurements of the fluorescence of Aβ’s single tyrosine intrinsic fluorophore (Tyr). The results suggest that quercetin binds β-amyloid oli ...
DOI:
10.1021/acs.jpcb.2c02763

17. New Triterpenoid and Anti-Inflammatory Constituents of Eriobotrya deflexa f. deflexa

Author:
Hui-Ming Chen; Chien-Ming Huang; Li-Chai Chen; Chang-Syun Yang; Tsung-Hsien Chang; Chun-Lin Chen; Ping-Jyun Sung; Wen-Lung Kuo; Ming-Jen Cheng; Jen-Wen Hsiao; Jih-Jung Chen
Source:
Chemistry of natural compounds 2022 v.58 no.3 pp. 496-500
ISSN:
0009-3130
Subject:
quercetin,   etc   ; Eriobotrya deflexa; chemistry; kaempferol; naringenin; spectroscopy; ursolic acid;     Show all 7 Subjects
Abstract:
... A new triterpenoid, methyl 2α-(4-hydroxybenzoyl)oxy-3β-hydroxy-urs-12-en-28-oate (1), has been isolated from the leaves of Eriobotrya deflexa f. deflexa, together with five known compounds, quercetin (2), kaempferol 3-O-β-glucoside (3), naringenin (4), ursolic acid (5), and euscaphic acid (6). The structure of new compound 1 was determined through spectroscopic and MS analyses. Among the isolates, ...
DOI:
10.1007/s10600-022-03718-6

18. Protein Engineering of PhUGT, a Donor Promiscuous Glycosyltransferase, for the Improved Enzymatic Synthesis of Antioxidant Quercetin 3-O-N-Acetylgalactosamine

Author:
Zhen Xu; Li-Li Hong; Chun-Sheng Liu; Jian-Qiang Kong
Source:
Journal of agricultural and food chemistry 2022 v.70 no.13 pp. 4076-4085
ISSN:
1520-5118
Subject:
quercetin,   etc   ; Petunia hybrida; antioxidant activity; antioxidants; food chemistry; sugars;     Show all 6 Subjects
Abstract:
... Quercetin 3-O-N-acetylgalactosamine (Q3GalNAc), a derivative of dietary hyperoside, had never been enzymatically synthesized due to the lack of well-identified N-acetylgalactosamine-transferase (GalNAc-T). Herein, PhUGT, an identified flavonoid 3-O-galactosyltransferase from Petunia hybrida, was demonstrated to display quercetin GalNAc-T activity, transferring a N-acetylgalactosamine (GalNAc) from ...
DOI:
10.1021/acs.jafc.2c01029

19. Bio-inspired synthesis of flavonoids incorporated CaCO3: Influence on the phase, morphology and mechanical strength of the composites

Author:
Debojit Paul; Gopal Das
Source:
Colloids and surfaces 2022 v.642 pp. 128720
ISSN:
0927-7757
Subject:
quercetin,   etc   ; calcite; gelatin; hesperidin; mechanical stress; strength (mechanics); vaterite;     Show all 7 Subjects
Abstract:
... Biominerals are composite materials that exhibit remarkable mechanical strength and properties and the organic molecules associated with the inorganic crystalline phase stand out as one of the most important reasons for this phenomenon. In this work, with the help of in vitro synthesized biominerals based on the flavonoids quercetin and hesperidin, we tried to elucidate the influence of these orga ...
DOI:
10.1016/j.colsurfa.2022.128720

20. Bioactive phenolic compounds from the flowers of Farfugium japonicum (L.) Kitam. var. giganteum (Siebold et Zucc.) Kitam. (Asteraceae)

Author:
Hari Prasad Devkota; Kazuki Tsushiro; Takashi Watanabe
Source:
Natural product research 2022 v.36 no.15 pp. 4036-4039
ISSN:
1478-6427
Subject:
quercetin,   etc   ; Japan; free radicals; research; rosmarinic acid; spectral analysis;     Show all 6 Subjects
Abstract:
... Farfugium japonicum (L.) Kitam. var. giganteum (Siebold et Zucc.) Kitam. is mainly distributed in the Kyushu and Shikoku Islands of Japan. The main aim of this study was to isolate and identify the chemical constituents of the 70% EtOH extract of the flowers of F. japonicum var. giganteum and to evaluate their tyrosinase inhibitory and free radical scavenging activities. Five phenolic compounds, n ...
DOI:
10.1080/14786419.2021.1903004