An official website of the United States government
Here’s how you know
Official websites use .gov
A .gov website belongs to an official government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.
antibiotic resistancegenes, etc ; antibiotic resistance; bacterial communities; feces; humans; pathogenicity; risk; risk reduction; sanitation; China; Show all 10 Subjects
Abstract:
... Chinese government is vigorously promoting toilet renovation in rural areas to reduce the risk of human feces exposure, which would cause infectious diseases, especially antibiotic resistance genes (ARGs) and pathogens. However, the distribution of ARGs in human feces from different regions of China remained ill-defined. It is not yet known how the survival of ARGs after toilet treatment is associ ...
antibiotic resistancegenes, etc ; Enterobacteriaceae; antibiotic resistance; antibiotics; bacterial communities; biogeography; community structure; data collection; lakes; metagenomics; risk; sediments; stochastic processes; China; Show all 14 Subjects
Abstract:
... Lakes act as one of the reservoirs and dispersal routes of antibiotic resistance genes (ARGs) and pathogenic resistant bacteria in aquatic environments. Previous studies reported the occurrence and distribution of ARGs in lakes worldwide; however, few investigated the biogeography and diversity patterns of antibiotic resistome in the environment. To fill this gap, a large-scale data set of sedimen ...
antibiotic resistancegenes, etc ; Achromobacter; Mycobacterium; Stenotrophomonas; ammonia; antibiotic resistance; antibiotics; autumn; biofilm; community structure; hardness; metagenomics; microbial communities; plasmids; plate count; seasonal variation; spring; suburban areas; summer; temperature; total organic carbon; water distribution; water treatment; winter; China; Show all 25 Subjects
Abstract:
... Antibiotic resistance genes (ARGs) are an emerging issue for drinking water safety. However, the seasonal variation of ARGs in drinking water distribution systems (DWDS) is still unclear. This work revealed the tempo-spatial changes of microbial community, ARGs, mobile genetic elements (MGEs) co-occurring with ARGs, ARG hosts in DWDS bulk water by means of metagenome assembly. The microbial commun ...
resistancegenes, etc ; Arachis hypogaea; chromosomes; peanuts; sequence analysis; Show all 5 Subjects
Abstract:
... A dominant rust resistance gene, VG 9514-Rgene was isolated through map-based cloning. Sequence analysis revealed non-synonymous mutations in the TIR, NBS and LRR region of the R-protein. Candidate gene-based markers from these SNPs revealed complete co-segregation of the isolated VG 9514-Rgene with rust resistance in a RIL population and confirmed their map position in between FRS 72 and SSR_GO34 ...
resistancegenes, etc ; mildews; monosaccharide transport proteins; powdery mildew; symbiosis; vacuoles; Show all 6 Subjects
Abstract:
... The Mildew Resistance Locus O (MLO) promotes both symbiosis and biotrophic interactions with fungi. MLO disruption results in powdery mildew resistance but is associated with growth defects. New research by Li et al. demonstrates that they can be rescued by ectopic activation of a vacuolar hexose transporter. ...
resistancegenes, etc ; animal manures; fertilizer application; fertilizers; heat tolerance; soil; tigecycline; China; Show all 8 Subjects
Abstract:
... The emergence of plasmid-mediated tigecycline-resistant genes [tet (×3) to tet (×6)] in animals and humans has raised serious concerns over their possible cross-environmental dissemination. However, behavior of these emerging mobile tet(X)-variant genes in manure treatment processes, particularly for different composting treatments, has not yet been studied. Here, we explored the environmental beh ...
resistancegenes, etc ; Mycosphaerella graminicola; Septoria; Turkey (country); leaf blotch; pathotypes; virulence; wheat; Show all 8 Subjects
Abstract:
... Septoria Leaf Blotch caused by Zymoseptoria tritici is a major disease of wheat affecting many wheat‐growing regions in the world. This study is the first to describe characteristics of the pathotype structure of Z. tritici isolates in Central Anatolia, Turkey, and to determine effective resistance genes for use in breeding strategies of Septoria Leaf Blotch Disease. Sixty isolates of Z. tritici w ...
resistancegenes, etc ; Puccinia graminis; genetic recombination; mutation; stem rust; virulence; wheat; Ethiopia; Show all 8 Subjects
Abstract:
... Stem rust caused by Puccinia graminis f. sp. tritici is one of Ethiopia's most serious wheat diseases. Because of mutation and genetic recombination, stem rust can rapidly evolve new virulence to resistant genes. The Ethiopian highlands are well‐known hotspots for the rapid emergence and spread of new wheat stem rust races. The objective of this study was to determine the virulence diversity and s ...
resistancegenes, etc ; agroecology; aquaponics; biotechnology; carbon; microbiology; nitrogen; nitrous oxide; risk; sulfadiazine; Show all 10 Subjects
Abstract:
... Antibiotics usage is a double-edged sword among the production promotion and environmental aggravation of aquaculture system. In this study, the effects of sulfadiazine addition on algal-bacterial-based aquaponic (AA) system were thoroughly investigated. Results showed that sulfadiazine addition increased the nitrogen (N) and carbon (C) recovery of AA system by 1.3 times and 2.9 times, respectivel ...
resistancegenes, etc ; Nicotiana benthamiana; amino acids; hypersensitive response; peptides; plant pathology; tomatoes; viruses; Show all 8 Subjects
Abstract:
... Sw‐5b is an effective resistance gene used widely in tomato to control tomato spotted wilt virus (TSWV), which causes severe losses in crops worldwide. Sw‐5b confers resistance by recognizing a 21‐amino‐acid peptide region of the viral movement protein NSm (NSm21, amino acids 115–135). However, C118Y or T120N mutation within this peptide region of NSm has given rise to field resistance‐breaking (R ...
antibiotic resistancegenes, etc ; antibiotic resistance; biosolids; metagenomics; research; risk assessment; sewage sludge; water; Show all 8 Subjects
Abstract:
... Centralized sludge treatment plants (CSTPs) are implicated as strong hotspots of antibiotic resistance genes (ARGs). However, the knowledge gap on the fate of intracellular and extracellular ARGs (iARGs and eARGs), and the functionality of resistant hosts limit risk assessment and management of CSTP resistome. Here, the flow of iARGs and eARGs across treatment units and analyses of ARG hosts were ...
resistancegenes, etc ; Tetrahymena thermophila; cost effectiveness; cycloheximide; eukaryotic cells; genetic engineering; molecular biology; Show all 7 Subjects
Abstract:
... Since the onset of molecular biology, the ciliate Tetrahymena thermophila has been one of the most convenient single-celled model eukaryotes for genetics, biochemistry, and cell biology. Particularly, thanks to the availability of several different selection markers, it is possible to knock out or knock in genes at multiple genetic loci simultaneously in Tetrahymena, which makes it an excellent mo ...
resistancegenes, etc ; Xanthomonas oryzae pv. oryzae; blight; microbiology; pathogens; pathotypes; rice; virulence; India; Show all 9 Subjects
Abstract:
... Bacterial blight (BB) of rice is a devastating disease caused by Xanthomonas oryzae pv. oryzae (Xoo). The evolution of new pathogenic races of bacterial blight pathogen is always a potential threat for rice production. The deployment of pathotype‐specific resistant genes in the host plants is a feasible strategy to develop BB‐resistant varieties. Therefore, continuous disease monitoring, identific ...
antibiotic resistancegenes, etc ; antibiotic resistance; antibiotics; biomarkers; environment; least squares; rivers; urbanization; watersheds; Show all 9 Subjects
Abstract:
... With growing concerns about antibiotic resistance, the tracking of antibiotic resistance genes (ARGs) in urban waterways will facilitate our increased understanding of the impact of urbanization on ARGs dissemination. In the current study, we assessed the ARGs profiles and antibiotic resistome in water samples along the Jiulong River basin, a distance of 250 km, to better understand the impact of ...
antibiotic resistancegenes, etc ; antibiotic resistance; antibiotics; field experimentation; organic fertilizers; pollution; protists; risk; Show all 8 Subjects
Abstract:
... Soil protists are key in regulating soil microbial communities. However, our understanding on the role of soil protists in shaping antibiotic resistome is limited. Here, we considered the diversity and composition of bacteria, fungi and protists in arable soils collected from a long-term field experiment with multiple fertilization treatments. We explored the effects of soil protists on antibiotic ...
resistancegenes, etc ; Arabidopsis thaliana; Brassica napus; crop quality; disease resistance; fungi; protein kinases; Show all 7 Subjects
Abstract:
... Various diseases severely affect Brassica crops, leading to significant global yield losses and a reduction in crop quality. In this study, we used the complete protein sequences of 49 cloned resistance genes (R genes) that confer resistance to fungal and bacterial diseases known to impact species in the Brassicaceae family. Homology searches were carried out across Brassica napus, B. rapa, B. ole ...
resistancegenes, etc ; Phytophthora fragariae; alleles; compliance; cultivars; heterozygosity; progeny; root rot; stele; strawberries; Show all 10 Subjects
Abstract:
... Background. Resistance to pathogens is an important breeding trait of a cultivar. Red stele root rot (Phytophthora fragariae var. fragariae Hickman) is a dangerous root disease. Revealing the patterns of resistance inheritance and identifying promising genotypes is an important stage in the development of strawberry cultivars resistant to red stele root rot. The purpose of the study was to identif ...
resistancegenes, etc ; Mycoplasma gallisepticum; RNA; animals; pathogenesis; phenotype; plasmids; site-directed mutagenesis; virulence; Show all 9 Subjects
Abstract:
... Mycoplasmas are important animal pathogens, but the functions and roles of many of their genes in pathogenesis remain unclear, in large part because of the limited tools available for targeted mutagenesis in these bacteria. In this study we used the Mycoplasma gallisepticum CRISPR/Cas system to target a nuclease gene, MGA_0637 (mnuA), which is predicted to play a role in survival and virulence. Ou ...
resistancegenes, etc ; Callosobruchus; Vigna radiata; agronomy; backcrossing; cultivars; loci; mung beans; phenotypic selection; Show all 9 Subjects
Abstract:
... Mung bean is vulnerable to bruchids (Callosobruchus spp.), resulting in low quality and losses worldwide. Developing resistant cultivars is the most effective, economical, and eco-friendly way to protect mung bean seeds from the damage of bruchids. Previously, we identified two gene loci that are tightly linked with bruchid resistance, which makes new cultivar development possible using molecular ...
resistancegenes, etc ; Solanum lycopersicum; Solanum pimpinellifolium; Stemphylium lycopersici; cultivars; leaf spot; loci; tomatoes; Show all 8 Subjects
Abstract:
... KEY MESSAGES: Gray leaf spot (GLS) resistance in tomato is controlled by one major dominant locus, Sm. Sm was fine mapped, and the nucleotide-binding site-leucine-rich repeat (NBS-LRR) gene Solyc11g020100 was identified as a candidate gene for Sm. Further functional analysis indicated that this gene confers high resistance to Stemphylium lycopersici in tomato. Tomato (Solanum Lycopersicum) is wide ...