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1. Erratum: Palma-Bautista et al. Resistance Mechanisms to 2,4-D in Six Different Dicotyledonous Weeds Around the World. Agronomy 2020, 10, 566

Author:
Candelario Palma-Bautista; Antonia M. Rojano-Delgado; Ignacio Dellaferrera; Jesús M. Rosario; Mario R. Vigna; Joel Torra; Rafael de Prado
Source:
Agronomy 2021 v.11 no.6 pp. -
ISSN:
2073-4395
Subject:
resistance mechanisms,   etc   ; 2,4-D; agronomy; weed control; weeds;     Show all 5 Subjects
Abstract:
... The authors would like to make the following correction to the published paper [...] ...
DOI:
10.3390/agronomy11061081

2. Recent Advances in the Understanding of Molecular Mechanisms of Resistance in Noctuid Pests

Author:
Gaëlle Le Goff; Ralf Nauen
Source:
Insects 2021 v.12 no.8 pp. -
ISSN:
2075-4450
Subject:
resistance mechanisms,   etc   ; Noctuidae; insects; pest resistance; plant pests;     Show all 5 Subjects
Abstract:
... Noctuid moths are among the most devastating crop pests on the planet [...] ...
DOI:
10.3390/insects12080674

3. Border Control: Regulating LPS Biogenesis

Author:
Randi L. Guest; Steven T. Rutherford; Thomas J. Silhavy
Source:
Trends in microbiology 2021 v.29 no.4 pp. 334-345
ISSN:
0966-842X
Subject:
resistance mechanisms,   etc   ; antibiotic resistance; antibiotics; bacterial outer membranes; glycolipids; lipid A; microbial physiology; phospholipids;     Show all 8 Subjects
Abstract:
... The outer membrane (OM) is a defining feature of Gram-negative bacteria that serves as a permeability barrier and provides rigidity to the cell. Critical to OM function is establishing and maintaining an asymmetrical bilayer structure with phospholipids in the inner leaflet and the complex glycolipid lipopolysaccharide (LPS) in the outer leaflet. Cells ensure this asymmetry by regulating the bioge ...
DOI:
10.1016/j.tim.2020.09.008

4. Evaluating the emergence of nonsusceptibility among Pseudomonas aeruginosa respiratory isolates from a phase-3 clinical trial for treatment of nosocomial pneumonia (ASPECT-NP)

Author:
Matthew G. Johnson; Christopher Bruno; Mariana Castanheira; Brian Yu; Jennifer A. Huntington; Patricia Carmelitano; Elizabeth G. Rhee; Carisa De Anda; Mary Motyl
Source:
International journal of antimicrobial agents 2021 v.57 no.3 pp. 106278
ISSN:
0924-8579
Subject:
resistance mechanisms,   etc   ; Pseudomonas aeruginosa; antibiotic resistance; bacterial pneumonia; clinical trials; cross infection; dosage; meropenem; respiratory system; yields;     Show all 10 Subjects
Abstract:
... Objectives: The emergence of nonsusceptibility to ceftolozane/tazobactam and meropenem was evaluated among Pseudomonas aeruginosa (P. aeruginosa) lower respiratory tract isolates obtained from participants in the ASPECT-NP clinical trial.Methods: ASPECT-NP was a phase-3, randomised, double-blind, multicentre trial that demonstrated noninferiority of 3 g ceftolozane/tazobactam q8h versus 1 g merope ...
DOI:
10.1016/j.ijantimicag.2021.106278

5. Crayfish (Procambarus clarkii) TRPA1 is required for the defense against Aeromonas hydrophila infection under high temperature conditions and contributes to heat sensing

Author:
Bo Liu; Xiaojun Song; Suhua Bai; Chaohua Dong
Source:
Comparative biochemistry and physiology 2022 v.257 pp. 110654
ISSN:
1096-4959
Subject:
resistance mechanisms,   etc   ; Aeromonas hydrophila; Procambarus clarkii; antioxidant activity; bacterial infections; circadian rhythm; crayfish; disease resistance; enzyme activity; gene silencing; heat stress; heat-shock protein 70; heat-shock protein 90; hemocytes; immune response; lipid peroxidation; monophenol monooxygenase; mortality; shellfish diseases; temperature; transient receptor potential channels;     Show all 21 Subjects
Abstract:
... Temperature is an important environmental factor influencing immune responses of crayfish. However, the mechanism underlying how temperature affects immune responses remains unclear. Here, we identified an ortholog of the transient receptor potential ankyrin subtype 1 (TRPA1), a temperature sensor of Drosophila, from Procambarus clarkii (PcTRPA1-1). Its expression was induced by high temperature a ...
DOI:
10.1016/j.cbpb.2021.110654

6. Antimicrobial drug resistance mechanisms among Mollicutes

Author:
Olga A. Chernova; Vladislav M. Chernov; Alexey A. Mouzykantov; Natalya B. Baranova; Inna A. Edelstein; Rustam I. Aminov
Source:
International journal of antimicrobial agents 2021 v.57 no.2 pp. 106253
ISSN:
0924-8579
Subject:
resistance mechanisms,   etc   ; Mollicutes; animal pathogenic bacteria; antibiotic resistance; antibiotic resistance genes; cell culture; commensalism; point mutation; stress tolerance;     Show all 9 Subjects
Abstract:
... Representatives of the Mollicutes class are the smallest, wall-less bacteria capable of independent reproduction. They are widespread in nature, most are commensals, and some are pathogens of humans, animals and plants. They are also the main contaminants of cell cultures and vaccine preparations. Despite limited biosynthetic capabilities, they are highly adaptable and capable of surviving under v ...
DOI:
10.1016/j.ijantimicag.2020.106253

7. Salt tolerance mechanisms in trees: research progress

Author:
Mingjing Zhang; Yanlu Liu; Guoliang Han; Yi Zhang; Baoshan Wang; Min Chen
Source:
Trees 2021 v.35 no.3 pp. 717-730
ISSN:
0931-1890
Subject:
resistance mechanisms,   etc   ; genetic improvement; genetic resistance; resistance genes; salt stress; salt tolerance; soil salinization; soil-plant interactions; tree growth; trees;     Show all 10 Subjects
Abstract:
... KEY MESSAGE: Our manuscript discussed salt tolerance mechanisms in trees, genes associated with salt stress tolerance, methods to improve the salt tolerance of trees, and research frontiers. Soil salinization is a global problem that seriously affects plant growth and development. Improving the salt tolerance of trees is an import economic and ecological aim in forestry. Recent studies have provid ...
DOI:
10.1007/s00468-020-02060-0

8. Prevalence and mechanisms of fosfomycin resistance among KPC-producing Klebsiella pneumoniae clinical isolates in China

Author:
Lin Huang; Min Cao; Yanyan Hu; Rong Zhang; Yufei Xiao; Gongxiang Chen
Source:
International journal of antimicrobial agents 2021 v.57 no.1 pp. 106226
ISSN:
0924-8579
Subject:
resistance mechanisms,   etc   ; Klebsiella pneumoniae; alpha-glycerophosphoric acid; antibiotic resistance; carbon; fosfomycin; hospitals; mutation; phenotype; prevalence; resistance genes; sequence analysis; sole; strains; testing; China;     Show all 16 Subjects
Abstract:
... The threat of antibiotic resistance has increased dramatically in recent years. Fosfomycin, an old antibiotic agent, has been re-introduced to fight infections caused by Klebsiella pneumoniae carbapenemase-producing K. pneumoniae (KPC-KP). However, the trend of fosfomycin resistance among KPC-KP strains is increasing. In this study, 80 KPC-KP clinical isolates were collected from three teaching ho ...
DOI:
10.1016/j.ijantimicag.2020.106226

9. Biodegradation of antibiotics: The new resistance determinants – part I

Author:
Ana C. Reis; Boris A. Kolvenbach; Olga C. Nunes; Philippe F.X. Corvini
Source:
New biotechnology 2020 v.54 pp. 34-51
ISSN:
1871-6784
Subject:
resistance mechanisms,   etc   ; aminoglycosides; biodegradation; human health; microbial communities; sulfonamides; tetracyclines; trimethoprim;     Show all 8 Subjects
Abstract:
... History shows that the discovery of, and the resistance to, antibiotics go hand in hand. While knowledge of resistance mechanisms, their impact and distribution is vast, over the years, the topic of antibiotic degradation has often been overlooked and regarded as being discrete from the research on resistance. As a result, understanding of the degradation of antibiotics and the impact of antibioti ...
DOI:
10.1016/j.nbt.2019.08.002

10. Influence of Cd exposure on H+ and Cd2+ fluxes in the leaf, stem and root of a novel aquatic hyperaccumulator - Microsorum pteropus

Author:
Xin-Yu Lan; Qi-Shuang He; Bin Yang; Yun-Yun Yan; Xin-Yuan Li; Fu-Liu Xu
Source:
Chemosphere 2020 v.249 pp. 126552
ISSN:
0045-6535
Subject:
resistance mechanisms,   etc   ; Microsorum; cadmium; hydroponics; hyperaccumulators; leaves; physiological transport; protons; roots; stems;     Show all 10 Subjects
Abstract:
... Microsorum pteropus has been proven to be a potential novel aquatic Cd hyperaccumulator. In this study, Non-invasive Micro-test Technology (NMT) was used to observe the ion fluxes of different M. pteropus tissues under Cd exposure. M. pteropus can hyperaccumulate more than 1000 mg/kg Cd in roots and leaves and approximately 600 mg/kg Cd in stems after seven days of exposure to 500 μM Cd, showing t ...
DOI:
10.1016/j.chemosphere.2020.126552

11. Do 1,8-naphthyridine sulfonamides possess an inhibitory action against Tet(K) and MsrA efflux pumps in multiresistant Staphylococcus aureus strains?

Author:
Cícera Datiane de Morais Oliveira-Tintino; Saulo Relison Tintino; Débora Feitosa Muniz; Cristina Rodrigues dos Santos Barbosa; Raimundo Luiz Silva Pereira; Iêda Maria Begnini; Ricardo Andrade Rebelo; Luiz Everson da Silva; Sandro Lucio Mireski; Michele Caroline Nasato; Maria Isabel Lacowicz Krautler; Pedro Silvino Pereira; Alexandre Magno Rodrigues Teixeira; Irwin Rose Alencar de Menezes; Henrique Douglas Melo Coutinho; Teresinha Gonçalves da Silva
Source:
Microbial pathogenesis 2020 v.147 pp. 104268
ISSN:
0882-4010
Subject:
resistance mechanisms,   etc   ; Staphylococcus aureus; antibacterial properties; antibiotics; aromatic compounds; ethidium; sulfonamides; synergism; transporters;     Show all 9 Subjects
Abstract:
... Naphthyridines represent a class of heterocyclic compounds formed by two condensed aromatic rings. This study aimed to evaluate the antibacterial activity and in vitro inhibition of efflux resistance mechanisms of a series of 1,8-naphthyridine sulfonamides against strains carrying Tet(K) and MsrA efflux pumps. The efflux pump inhibitory capacity was evaluated by analyzing synergistic effects betwe ...
DOI:
10.1016/j.micpath.2020.104268

12. Eukaryotic Translation Initiation Factors Shape RNA Viruses Resistance in Plants

Author:
Jannat Shopan; Xiaolong Lv; Zhongyuan Hu; Mingfang Zhang; Jinghua Yang
Source:
Horticultural plant journal 2020 v.6 no.2 pp. 81-88
ISSN:
2468-0141
Subject:
resistance mechanisms,   etc   ; Potyvirus; RNA; crop yield; genetic resistance; loci; mutation; protein synthesis; resistance genes; viruses;     Show all 10 Subjects
Abstract:
... Viruses are representative of a global threat to agricultural production. Genetic resistance is the preferred strategy for the control of viral infection and against loss of crop yield. Viral protein synthesis requires host cellular factors for translating their viral RNAs, and for regulating their replication and cell to cell systemic movement. Therefore, the viruses are dependent on cellular tra ...
DOI:
10.1016/j.hpj.2020.03.001

13. Molecular basis of antimicrobial resistance in Mycoplasma genitalium

Author:
Thomas E. van der Schalk; Joyce F. Braam; Johannes G. Kusters
Source:
International journal of antimicrobial agents 2020 v.55 no.4 pp. 105911
ISSN:
0924-8579
Subject:
resistance mechanisms,   etc   ; DNA; Mycoplasma genitalium; antibiotic resistance; azithromycin; disease transmission; microbiology; moxifloxacin; mutation; pathogens; therapeutics;     Show all 11 Subjects
Abstract:
... Mycoplasma genitalium is a sexually transmitted urogenital pathogen, and infection can result in serious symptoms. As M. genitalium is rather difficult to culture, infections are usually detected by molecular methods. Unfortunately, there has recently been a significant increase in resistance to azithromycin and moxifloxacin used for the treatment of M. genitalium infections. The increased resista ...
DOI:
10.1016/j.ijantimicag.2020.105911

14. Co-occurrence of aminoglycoside and β-lactam resistance mechanisms in aminoglycoside- non-susceptible Escherichia coli isolated in the Zurich area, Switzerland

Author:
Elias Bodendoerfer; Martina Marchesi; Frank Imkamp; Patrice Courvalin; Erik C. Böttger; Stefano Mancini
Source:
International journal of antimicrobial agents 2020 v.56 no.1 pp. 106019
ISSN:
0924-8579
Subject:
resistance mechanisms,   etc   ; Escherichia coli; aminoglycosides; anti-infective agents; area; genotype; resistance genes; strains; therapeutics; Switzerland;     Show all 10 Subjects
Abstract:
... The co-occurrence of aminoglycoside and β-lactam resistance was assessed in 3358 consecutive Escherichia coli clinical isolates collected in 2014 in the greater Zurich area, Switzerland. Non-susceptibility to at least one of the tested aminoglycosides was observed in 470/3358 E. coli strains (14%). In strains categorized as broad-spectrum β-lactamase (BSBL)-producers (1241/3358 isolates), extended ...
DOI:
10.1016/j.ijantimicag.2020.106019

15. The acid response network of Staphylococcus aureus

Author:
Chunyi Zhou; Paul D Fey
Source:
Current opinion in microbiology 2020 v.55 pp. 67-73
ISSN:
1369-5274
Subject:
resistance mechanisms,   etc   ; Staphylococcus aureus; acid tolerance; digestive system; mammals; niches; organic acids and salts; pH; regulon;     Show all 9 Subjects
Abstract:
... Staphylococcus aureus colonizes or causes infection in a multitude of niches within a mammalian host. Many of these niches are acidic, yet specific pH resistance mechanisms that facilitate survival have not been thoroughly investigated. This review discusses recent studies documenting known acid resistance mechanisms in S. aureus and other staphylococcal species. However, studies that clearly defi ...
DOI:
10.1016/j.mib.2020.03.006

16. Bacteriophage-host arm race: an update on the mechanism of phage resistance in bacteria and revenge of the phage with the perspective for phage therapy

Author:
Aa Haeruman Azam; Yasunori Tanji
Source:
Applied microbiology and biotechnology 2019 v.103 no.5 pp. 2121-2131
ISSN:
0175-7598
Subject:
resistance mechanisms,   etc   ; antibiotics; bacteria; bacteriophages; phage therapy;     Show all 5 Subjects
Abstract:
... Due to a constant attack by phage, bacteria in the environment have evolved diverse mechanisms to defend themselves. Several reviews on phage resistance mechanisms have been published elsewhere. Thanks to the advancement of molecular techniques, several new phage resistance mechanisms were recently identified. For the practical phage therapy, the emergence of phage-resistant bacteria could be an o ...
DOI:
10.1007/s00253-019-09629-x

17. Nanosecond electric pulses rapidly enhance the inactivation of Gram-negative bacteria using Gram-positive antibiotics

Author:
Ram Anand Vadlamani; Agni Dhanabal; David A. Detwiler; Rusha Pal; James McCarthy; Mohamed N. Seleem; Allen L. Garner
Source:
Applied microbiology and biotechnology 2020 v.104 no.5 pp. 2217-2227
ISSN:
0175-7598
Subject:
resistance mechanisms,   etc   ; Escherichia coli; Gram-negative bacteria; Pseudomonas aeruginosa; Staphylococcus aureus; erythromycin; mechanism of action; rifampicin; vancomycin;     Show all 9 Subjects
Abstract:
... Physically disrupting microorganism membranes to enable antibiotics to overcome resistance mechanisms that inhibit or excrete antibiotics has great potential for reducing antibiotic doses and rendering resistance mechanisms inert. We demonstrate the synergistic inactivation of a Gram-positive (Staphylococcus aureus) and two Gram-negative (Escherichia coli and Pseudomonas aeruginosa) bacteria by co ...
DOI:
10.1007/s00253-020-10365-w

18. Amino Acid k-mer Feature Extraction for Quantitative Antimicrobial Resistance (AMR) Prediction by Machine Learning and Model Interpretation for Biological Insights

Author:
Taha ValizadehAslani; Zhengqiao Zhao; Bahrad A. Sokhansanj; Gail L. Rosen
Source:
Biology 2020 v.9 no.11 pp. -
ISSN:
2079-7737
Subject:
resistance mechanisms,   etc   ; accuracy; algorithms; amino acids; antibiotic resistance; artificial intelligence; extraction; information; models; nucleotide sequences; oligopeptides; prediction;     Show all 12 Subjects
Abstract:
... Machine learning algorithms can learn mechanisms of antimicrobial resistance from the data of DNA sequence without any a priori information. Interpreting a trained machine learning algorithm can be exploited for validating the model and obtaining new information about resistance mechanisms. Different feature extraction methods, such as SNP calling and counting nucleotide k-mers have been proposed ...
DOI:
10.3390/biology9110365

19. Mechanism of plant immune activation and signaling: Insight from the first solved plant resistosome structure

Author:
Baomin Feng; Dingzhong Tang
Source:
Journal of integrative plant biology 2019 v.61 no.8 pp. 902-907
ISSN:
1672-9072
Subject:
resistance mechanisms,   etc   ; immunologic receptors; plant proteins; signal transduction;     Show all 4 Subjects
Abstract:
... This commentary introduces an exciting breakthrough: the first solved structure of a plant NLR immune receptor complex. The significance of this work, including the similarity between the activation of NLRs from plants and animals, and potentially novel mechanism of immune signaling in plants, were discussed and put into perspective. ...
DOI:
10.1111/jipb.12814

20. A Genome Resource for Several North American Venturia inaequalis Isolates with Multiple Fungicide Resistance Phenotypes

Author:
Franz J. Lichtner; Wayne M. Jurick; Katrin M. Ayer; Verneta L. Gaskins; Sara M. Villani; Kerik D. Cox
Source:
Phytopathology 2020 v.110 no.3 pp. 544-546
ISSN:
0031-949X
Subject:
resistance mechanisms,   etc   ; Venturia inaequalis; apple scab; apples; disease control; fungi; fungicide resistance; fungicides; genome; pathogens; pesticide application; phenotype; virulence;     Show all 13 Subjects
Abstract:
... The apple scab pathogen, Venturia inaequalis, is among the most economically important fungal pathogens that affects apples. Fungicide applications are an essential part of disease management. Implementation of cultural practices and genetic sources of resistance in the host are vital components of scab management. This is the first presentation of multiple, high quality, well-annotated genomes of ...
DOI:
10.1094/PHYTO-06-19-0222-A