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riskfactors, etc ; fibrosis; genes; genetic markers; genotype; lymphoma; patients; Show all 7 Subjects
Abstract:
... Introduction: The onset of the Philadelphia chromosome-negative myeloproliferative neoplasms (MPNs) is caused by acquired somatic mutations in target myeloid genes “driver mutations”. The CCL2 gene is overexpressed by non-Hodgkin lymphomas and multiple solid tumors. Aim of the study: to evaluate the possible association of CCL2 rs1024611 SNP and its expression level and the risk of developing Phil ...
riskfactors, etc ; alleles; anxiety; homozygosity; loci; mental depression; personality; Show all 7 Subjects
Abstract:
... Searching for genetic causes of depressive and anxiety disorders has been going on for about three decades. However, the accumulated experimental data do not allow us to come to a final conclusion about the influence of certain genes on the risk of the disease and the severity of its course. Most studies of candidate genes were carried out using samples of patients with different nosological forms ...
riskfactors, etc ; cattle; edema; myiasis; umbilical cord; Brazil; Canada; Show all 7 Subjects
Abstract:
... The objective of this scoping review was to describe and characterize the existing literature regarding umbilical health and identify gaps in knowledge. Six databases were searched for studies examining umbilical health in an intensively raised cattle population. There were 4249 articles initially identified; from these, 723 full text articles were then screened, with 150 articles included in the ...
riskfactors, etc ; childhood obesity; meta-analysis; models; systematic review; Show all 5 Subjects
Abstract:
... It is unclear whether maternal working time has an impact on offspring's weight‐related outcomes especially obesity; the objective of this study is to conduct the first meta‐analysis to focus on this topic. We searched PubMed, Ovid, and Web of Science databases through August 2021. A random‐effect model was used to assess the pooled odds ratios (ORs) and regression coefficients (β) with their corr ...
riskfactors, etc ; caregivers; monitoring; quality of life; rural health; Show all 5 Subjects
Abstract:
... OBJECTIVES: Rural‐urban health disparities are pervasive among older adults. Rural US locations have a disproportionately high population of older adults, have reduced access to services, and are therefore more reliant on family and friends for care. However, little is known about rural‐urban disparities among the 40+ million informal caregivers nationwide. There is a critical need to understand h ...
riskfactors, etc ; alleles; coronary artery disease; genotyping; homozygosity; regression analysis; Show all 6 Subjects
Abstract:
... Recent genome-wide association studies reported the association of polymorphic alleles of PHACTR1 (rs9349379 (G)), CDDKN2B-AS1 (rs2891168 (G)), COL4A2 (rs11838776 (A)) and SOD2 (rs4880 (T)) with increased risk of coronary artery disease (CAD). The aim of our study was to assess the association of genetic variants with risk of CAD and its severity and in Southeast Iranian population. This study was ...
riskfactors, etc ; biosynthesis; electromagnetic field; endometrium; estrone; oxidoreductases; progesterone; swine; Show all 8 Subjects
Abstract:
... The electromagnetic field (EMF) is an environmental risk factor that may impair living organisms. This study aims to determine the functional effects of EMF exposure at 50 and 120 Hz for 2 or 4 h on estrogen synthesis and release in the endometrium. Endometrial slices were isolated from pigs (n = 5) during the peri-implantation period. To check whether progesterone (P₄) exerts any protective effec ...
riskfactors, etc ; antioxidants; bean flour; chelation; chickpeas; drugs; hypertension; lentils; Show all 8 Subjects
Abstract:
... The legume consumption is increasing because this food represents a rich and sustainable source of plant proteins and biological activities considered effective in the prevention of some chronic diseases, including those age-related. With the aim to characterize functional properties of some legume foodstuffs, the total polyphenolic content and the antioxidant, metal chelation and ACE-inhibitory a ...
Esbeidy García-Flores; José Manuel Rodríguez-Pérez; Verónica Marusa Borgonio-Cuadra; Gilberto Vargas-Alarcón; Juan Calderón-Colmenero; Juan Pablo Sandoval; José Antonio García-Montes; Víctor Manuel Espinoza-Gutiérrez; Juan Gerardo Reyes-García; Benny Giovanni Cazarín-Santos; Antonio Miranda-Duarte; Armando Gamboa-Domínguez; Nonanzit Pérez-Hernández
riskfactors, etc ; DNA methylation; epigenetics; genes; heart; high-throughput nucleotide sequencing; Show all 6 Subjects
Abstract:
... The TBX5 gene regulates morphological changes during heart development, and it has been associated with epigenetic abnormalities observed in congenital heart defects (CHD). The aim of this research was to evaluate the association between DNA methylation levels of the TBX5 gene promoter and congenital septal defects. DNA methylation levels of six CpG sites in the TBX5 gene promoter were evaluated u ...
riskfactors, etc ; Latinos; appetite; childhood obesity; children; food intake; food quality; Show all 7 Subjects
Abstract:
... Childhood obesity prevalence is high among children from immigrant/refugee households who live in high-income countries. Poor child dietary intake is a critical risk factor for elevated obesity prevalence and food parenting practices have been found to be associated with child dietary intake and eating behaviors. The main aim of this study was to examine the associations between migrants'/refugees ...
riskfactors, etc ; educational status; income; insurance; lung neoplasms; monitoring; rural health; Show all 7 Subjects
Abstract:
... PURPOSE: The US Preventive Services Task Force recommends lung cancer screening with Low‐Dose Computed Tomography (LDCT) in high‐risk individuals. Our objective was to identify demographic, health, and financial factors associated with screening uptake, with a focus on urban–rural differences. METHODS: We analyzed data from the 2018 and 2019 Behavioral Risk Factor Surveillance System and its optio ...
riskfactors, etc ; air pollution; cohort studies; environmental exposure; lifestyle; lung neoplasms; Show all 6 Subjects
Abstract:
... Genetic variants and modifiable risk factors (including environmental exposure and lifestyle) greatly contribute to the development of lung cancer. The population attributable fraction (PAF) of these risk factors, especially their interactive effects, has not been well quantified. A total of 398,577 participants were included in this analysis. There were 2504 incident lung cancer cases identified ...
riskfactors, etc ; Shuni orthobunyavirus; epizootic diseases; insecticide application; seroprevalence; sheep; South Korea; Show all 7 Subjects
Abstract:
... Aino virus infection is responsible for epizootic and/or sporadic outbreaks of abortions, stillbirths and premature delivery among pregnant ruminants. The epizootiology of Aino virus infection is poorly defined in South Korea, therefore our aim was to assess its seroprevalence among sheep and goats. We also wanted to evaluate management and regional risk factors that might influence the frequency ...
riskfactors, etc ; bioinformatics; computer simulation; models; neoplasm progression; pollution; prognosis; prostatic neoplasms; toxicology; Show all 9 Subjects
Abstract:
... Industries have begun to shift their focus on exploring substitute chemicals for BPA due to their concerns about safety and environmental pollution. In recent years, alternative bisphenols, including BPS, BPF, and BPAF have been extensively used as BPA substitutes. Based on previous studies, BPA is considered a risk factor for prostate cancer. This work aims to explore the interactive genes relate ...
riskfactors, etc ; disease susceptibility; epidemiology; etiology; heart; heart diseases; models; morphogenesis; Saudi Arabia; Show all 9 Subjects
Abstract:
... Congenital heart disease (CHD) encompasses a wide range of structural defects of the heart and, in many cases, the factors that predispose an individual to disease are not well understood, highlighting the remarkable complexity of CHD etiology. Evidence of familial aggregation of CHD has been demonstrated in different communities and for different cardiac lesions. Consanguinity, particularly among ...
riskfactors, etc ; Aesculus; dietetics; eating disorders; food quality; lifestyle; physical activity; questionnaires; sports; Show all 9 Subjects
Abstract:
... Orthorexia nervosa (ON) is defined as the excessive attention on healthy eating, and studies especially focused on food quality ON prevalence in university students can be extremely variable. The objective of this study is to investigate whether there was a difference in ON risk between health-scientific, economic-humanistic, sport sciences and dietetics and nutrition students, and to evaluate if ...
riskfactors, etc ; biomarkers; carcinogenesis; interphase; lipids; lung neoplasms; lungs; survival rate; therapeutics; tobacco; Show all 10 Subjects
Abstract:
... Lung cancer is the foremost cause of cancer related mortality among men and one of the most fatal cancers among women. Notably, the 5-year survival rate of lung cancer is very low; 5% in developing countries. This low survival rate can be attributed to factors like late stage diagnosis, rapid postoperative recurrences in the patients undergoing treatment and development of chemoresistance against ...
riskfactors, etc ; COVID-19 infection; adenosine triphosphate; air pollutants; death; inflammasomes; particulates; research; Show all 8 Subjects
Abstract:
... Fine particulate matter (PM₂.₅) has been the primary air pollutant and the fourth leading risk factor for disease and death in the world. Exposure to PM₂.₅ is related to activation of the NOD-like receptor family pyrin domain containing 3 (NLRP3) inflammasome, but the mechanism of PM₂.₅ affecting the NLRP3 inflammasome is still unclear. Previous studies have shown that PM₂.₅ can cause alterations ...
riskfactors, etc ; appetite; body mass index; celiac disease; distress; females; gastrointestinal system; surveys; Show all 8 Subjects
Abstract:
... An adverse relationship between coeliac disease and the development of disordered eating patterns is well established. The aim of this study was to replicate and extend Satherley et al.‘s (2016) study exploring coeliac-specific and non-specific factors predicting disordered eating. An online survey was completed by 187 adults with coeliac disease (90.4% female; Mean age = 48.92; Mean years living ...
riskfactors, etc ; Eisenia fetida; mortality; pollution; rivers; soil; specific growth rate; weight gain; Show all 8 Subjects
Abstract:
... The qualitative trials were conducted by exposing earthworms to diverse contaminants sources using standard earthworms’ avoidance tests (considered useful ab initio indicators). For two years, we observed the Jiu River pollution points. We observed soil traits in 15 sampling points from two neighboring Romanian counties where Jiu River flows, by evaluating the risk of pollution on Eisenia fetida e ...