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1. CCL2 rs1024611Gene Polymorphism in Philadelphia-Negative Myeloproliferative Neoplasms

Author:
Hossam Hodeib; Dina Abd EL Hai; Mohamed A Tawfik; Alzahraa A. Allam; Amal Selim; Abdallah Ahmed Elsawy; Amira Youssef
Source:
Genes 2022 v.13 no.3 pp. -
ISSN:
2073-4425
Subject:
risk factors,   etc   ; fibrosis; genes; genetic markers; genotype; lymphoma; patients;     Show all 7 Subjects
Abstract:
... Introduction: The onset of the Philadelphia chromosome-negative myeloproliferative neoplasms (MPNs) is caused by acquired somatic mutations in target myeloid genes “driver mutations”. The CCL2 gene is overexpressed by non-Hodgkin lymphomas and multiple solid tumors. Aim of the study: to evaluate the possible association of CCL2 rs1024611 SNP and its expression level and the risk of developing Phil ...
DOI:
10.3390/genes13030492

2. Common and Specific Genetic Risk Factors for Three Disorders with Depressive Symptoms

Author:
E. I. Rafikova; D. V. Shibalev; M. I. Shadrina; P. A. Slominsky; A. B. Guekht; A. P. Ryskov; V. A. Vasilyev
Source:
Russian journal of genetics 2022 v.58 no.1 pp. 65-72
ISSN:
1022-7954
Subject:
risk factors,   etc   ; alleles; anxiety; homozygosity; loci; mental depression; personality;     Show all 7 Subjects
Abstract:
... Searching for genetic causes of depressive and anxiety disorders has been going on for about three decades. However, the accumulated experimental data do not allow us to come to a final conclusion about the influence of certain genes on the risk of the disease and the severity of its course. Most studies of candidate genes were carried out using samples of patients with different nosological forms ...
DOI:
10.1134/S1022795422010100

3. Describing and Characterizing the Literature Regarding Umbilical Health in Intensively Raised Cattle: A Scoping Review

Author:
Matthew B. Van Camp; David L. Renaud; Todd F. Duffield; Diego E. Gomez; William J. McFarlane; Joanne Marshall; Charlotte B. Winder
Source:
Veterinary sciences 2022 v.9 no.6 pp. -
ISSN:
2306-7381
Subject:
risk factors,   etc   ; cattle; edema; myiasis; umbilical cord; Brazil; Canada;     Show all 7 Subjects
Abstract:
... The objective of this scoping review was to describe and characterize the existing literature regarding umbilical health and identify gaps in knowledge. Six databases were searched for studies examining umbilical health in an intensively raised cattle population. There were 4249 articles initially identified; from these, 723 full text articles were then screened, with 150 articles included in the ...
DOI:
10.3390/vetsci9060288

4. Maternal long working hours and offspring's weight‐related outcomes: A systematic review and meta‐analysis

Author:
Yiling Lou; Yi Zhu; Qiqi You; Qingqing Jiang; Xin Meng; Hongkun Di; Hongbin Xu; Yong Gan; Zuxun Lu; Shiyi Cao
Source:
Obesity reviews 2022 v.23 no.6 pp. e13439
ISSN:
1467-7881
Subject:
risk factors,   etc   ; childhood obesity; meta-analysis; models; systematic review;     Show all 5 Subjects
Abstract:
... It is unclear whether maternal working time has an impact on offspring's weight‐related outcomes especially obesity; the objective of this study is to conduct the first meta‐analysis to focus on this topic. We searched PubMed, Ovid, and Web of Science databases through August 2021. A random‐effect model was used to assess the pooled odds ratios (ORs) and regression coefficients (β) with their corr ...
DOI:
10.1111/obr.13439

5. Rural‐urban differences in informal caregiving and health‐related quality of life

Author:
Steven A. Cohen; Neelam Ahmed; Monique J. Brown; Marissa R. Meucci; Mary L. Greaney
Source:
Journal of rural health 2022 v.38 no.2 pp. 442-456
ISSN:
0890-765X
Subject:
risk factors,   etc   ; caregivers; monitoring; quality of life; rural health;     Show all 5 Subjects
Abstract:
... OBJECTIVES: Rural‐urban health disparities are pervasive among older adults. Rural US locations have a disproportionately high population of older adults, have reduced access to services, and are therefore more reliant on family and friends for care. However, little is known about rural‐urban disparities among the 40+ million informal caregivers nationwide. There is a critical need to understand h ...
DOI:
10.1111/jrh.12581

6. A Study of Associations Between rs9349379 (PHACTR1), rs2891168 (CDKN2B-AS), rs11838776 (COL4A2) and rs4880 (SOD2) Polymorphic Variants and Coronary Artery Disease in Iranian Population

Author:
Abolfazl Yari; Nasrollah Saleh-Gohari; Moghaddameh Mirzaee; Fatemeh Hashemi; Kolsoum Saeidi
Source:
Biochemical genetics 2022 v.60 no.1 pp. 106-126
ISSN:
0006-2928
Subject:
risk factors,   etc   ; alleles; coronary artery disease; genotyping; homozygosity; regression analysis;     Show all 6 Subjects
Abstract:
... Recent genome-wide association studies reported the association of polymorphic alleles of PHACTR1 (rs9349379 (G)), CDDKN2B-AS1 (rs2891168 (G)), COL4A2 (rs11838776 (A)) and SOD2 (rs4880 (T)) with increased risk of coronary artery disease (CAD). The aim of our study was to assess the association of genetic variants with risk of CAD and its severity and in Southeast Iranian population. This study was ...
DOI:
10.1007/s10528-021-10089-0

7. Electromagnetic field exposure alters in vitro estrogen biosynthesis and its release by the porcine endometrium in the peri-implantation period

Author:
Wiktoria Kozlowska; Ewa Monika Drzewiecka; Agata Zmijewska; Anita Franczak
Source:
Reproductive Biology 2022 v.22 no.2 pp. 100642
ISSN:
1642-431X
Subject:
risk factors,   etc   ; biosynthesis; electromagnetic field; endometrium; estrone; oxidoreductases; progesterone; swine;     Show all 8 Subjects
Abstract:
... The electromagnetic field (EMF) is an environmental risk factor that may impair living organisms. This study aims to determine the functional effects of EMF exposure at 50 and 120 Hz for 2 or 4 h on estrogen synthesis and release in the endometrium. Endometrial slices were isolated from pigs (n = 5) during the peri-implantation period. To check whether progesterone (P₄) exerts any protective effec ...
DOI:
10.1016/j.repbio.2022.100642

8. Healthy biological activities in legume flours from industrial cooking

Author:
Ivana Giangrieco; Maurizio Tamburrini; Lisa Tuppo; Maria Silvia Pasquariello; Maria Antonietta Ciardiello
Source:
Food bioscience 2022 v.48 pp. 101743
ISSN:
2212-4292
Subject:
risk factors,   etc   ; antioxidants; bean flour; chelation; chickpeas; drugs; hypertension; lentils;     Show all 8 Subjects
Abstract:
... The legume consumption is increasing because this food represents a rich and sustainable source of plant proteins and biological activities considered effective in the prevention of some chronic diseases, including those age-related. With the aim to characterize functional properties of some legume foodstuffs, the total polyphenolic content and the antioxidant, metal chelation and ACE-inhibitory a ...
DOI:
10.1016/j.fbio.2022.101743

9. DNA Methylation Levels of the TBX5 Gene Promoter Are Associated with Congenital Septal Defects in Mexican Paediatric Patients

Author:
Esbeidy García-Flores; José Manuel Rodríguez-Pérez; Verónica Marusa Borgonio-Cuadra; Gilberto Vargas-Alarcón; Juan Calderón-Colmenero; Juan Pablo Sandoval; José Antonio García-Montes; Víctor Manuel Espinoza-Gutiérrez; Juan Gerardo Reyes-García; Benny Giovanni Cazarín-Santos; Antonio Miranda-Duarte; Armando Gamboa-Domínguez; Nonanzit Pérez-Hernández
Source:
Biology 2022 v.11 no.1 pp. -
ISSN:
2079-7737
Subject:
risk factors,   etc   ; DNA methylation; epigenetics; genes; heart; high-throughput nucleotide sequencing;     Show all 6 Subjects
Abstract:
... The TBX5 gene regulates morphological changes during heart development, and it has been associated with epigenetic abnormalities observed in congenital heart defects (CHD). The aim of this research was to evaluate the association between DNA methylation levels of the TBX5 gene promoter and congenital septal defects. DNA methylation levels of six CpG sites in the TBX5 gene promoter were evaluated u ...
DOI:
10.3390/biology11010096

10. How time in the US and race/ethnicity shape food parenting practices and child diet quality

Author:
Sally I. Othman; Angela Fertig; Amanda Trofholz; Jerica M. Berge
Source:
Appetite 2022 v.171 pp. 105870
ISSN:
0195-6663
Subject:
risk factors,   etc   ; Latinos; appetite; childhood obesity; children; food intake; food quality;     Show all 7 Subjects
Abstract:
... Childhood obesity prevalence is high among children from immigrant/refugee households who live in high-income countries. Poor child dietary intake is a critical risk factor for elevated obesity prevalence and food parenting practices have been found to be associated with child dietary intake and eating behaviors. The main aim of this study was to examine the associations between migrants'/refugees ...
DOI:
10.1016/j.appet.2021.105870

11. Low‐dose CT lung cancer screening uptake: A rural–urban comparison

Author:
Anja Zgodic; Whitney E. Zahnd; Shailesh Advani; Jan M. Eberth
Source:
Journal of rural health 2022 v.38 no.1 pp. 40-53
ISSN:
0890-765X
Subject:
risk factors,   etc   ; educational status; income; insurance; lung neoplasms; monitoring; rural health;     Show all 7 Subjects
Abstract:
... PURPOSE: The US Preventive Services Task Force recommends lung cancer screening with Low‐Dose Computed Tomography (LDCT) in high‐risk individuals. Our objective was to identify demographic, health, and financial factors associated with screening uptake, with a focus on urban–rural differences. METHODS: We analyzed data from the 2018 and 2019 Behavioral Risk Factor Surveillance System and its optio ...
DOI:
10.1111/jrh.12568

12. Population attributable fraction of lung cancer due to genetic variants, modifiable risk factors, and their interactions: a nationwide prospective cohort study

Author:
Xiaojie Wang; Zhengmin (Min) Qian; Zilong Zhang; Miao Cai; Lan Chen; Yinglin Wu; Haitao Li; Echu Liu; Stephen Edward McMillin; Hualiang Lin
Source:
Chemosphere 2022 v.301 pp. 134773
ISSN:
0045-6535
Subject:
risk factors,   etc   ; air pollution; cohort studies; environmental exposure; lifestyle; lung neoplasms;     Show all 6 Subjects
Abstract:
... Genetic variants and modifiable risk factors (including environmental exposure and lifestyle) greatly contribute to the development of lung cancer. The population attributable fraction (PAF) of these risk factors, especially their interactive effects, has not been well quantified. A total of 398,577 participants were included in this analysis. There were 2504 incident lung cancer cases identified ...
DOI:
10.1016/j.chemosphere.2022.134773

13. Factors associated with seropositivity to Aino virus among sheep and goats in South Korea

Author:
Jeong-Min Hwang; Yun Ji Ga; Jung-Yong Yeh
Source:
Acta veterinaria Hungarica 2022 pp. -
ISSN:
1588-2705
Subject:
risk factors,   etc   ; Shuni orthobunyavirus; epizootic diseases; insecticide application; seroprevalence; sheep; South Korea;     Show all 7 Subjects
Abstract:
... Aino virus infection is responsible for epizootic and/or sporadic outbreaks of abortions, stillbirths and premature delivery among pregnant ruminants. The epizootiology of Aino virus infection is poorly defined in South Korea, therefore our aim was to assess its seroprevalence among sheep and goats. We also wanted to evaluate management and regional risk factors that might influence the frequency ...
DOI:
10.1556/004.2022.00015

14. Comprehensive analysis based in silico study of alternative bisphenols – Environmental explanation of prostate cancer progression

Author:
Kai Fang; Yang Li; Yuqing Zhang; Shengjie Liang; Simin Li; Dong Liu
Source:
Toxicology 2022 v.465 pp. 153051
ISSN:
0300-483X
Subject:
risk factors,   etc   ; bioinformatics; computer simulation; models; neoplasm progression; pollution; prognosis; prostatic neoplasms; toxicology;     Show all 9 Subjects
Abstract:
... Industries have begun to shift their focus on exploring substitute chemicals for BPA due to their concerns about safety and environmental pollution. In recent years, alternative bisphenols, including BPS, BPF, and BPAF have been extensively used as BPA substitutes. Based on previous studies, BPA is considered a risk factor for prostate cancer. This work aims to explore the interactive genes relate ...
DOI:
10.1016/j.tox.2021.153051

15. Consanguinity and Congenital Heart Disease Susceptibility: Insights into Rare Genetic Variations in Saudi Arabia

Author:
Nour Albesher; Salam Massadeh; Sabah M. Hassan; Manal Alaamery
Source:
Genes 2022 v.13 no.2 pp. -
ISSN:
2073-4425
Subject:
risk factors,   etc   ; disease susceptibility; epidemiology; etiology; heart; heart diseases; models; morphogenesis; Saudi Arabia;     Show all 9 Subjects
Abstract:
... Congenital heart disease (CHD) encompasses a wide range of structural defects of the heart and, in many cases, the factors that predispose an individual to disease are not well understood, highlighting the remarkable complexity of CHD etiology. Evidence of familial aggregation of CHD has been demonstrated in different communities and for different cardiac lesions. Consanguinity, particularly among ...
DOI:
10.3390/genes13020354

16. Lifestyle-Related Risk Factors of Orthorexia Can Differ among the Students of Distinct University Courses

Author:
Monica Guglielmetti; Ottavia Eleonora Ferraro; Ilaria Silvia Rossella Gorrasi; Elisabetta Carraro; Simona Bo; Giovanni Abbate-Daga; Anna Tagliabue; Cinzia Ferraris
Source:
Nutrients 2022 v.14 no.5 pp. -
ISSN:
2072-6643
Subject:
risk factors,   etc   ; Aesculus; dietetics; eating disorders; food quality; lifestyle; physical activity; questionnaires; sports;     Show all 9 Subjects
Abstract:
... Orthorexia nervosa (ON) is defined as the excessive attention on healthy eating, and studies especially focused on food quality ON prevalence in university students can be extremely variable. The objective of this study is to investigate whether there was a difference in ON risk between health-scientific, economic-humanistic, sport sciences and dietetics and nutrition students, and to evaluate if ...
DOI:
10.3390/nu14051111

17. Loss of TIPE3 reduced the proliferation, survival and migration of lung cancer cells through inactivation of Akt/mTOR, NF-κB, and STAT-3 signaling cascades

Author:
Devivasha Bordoloi; Choudhary Harsha; Ganesan Padmavathi; Kishore Banik; Bethsebie Lalduhsaki Sailo; Nand Kishor Roy; Sosmitha Girisa; Krishan Kumar Thakur; Amrita Devi Khwairakpam; Arunachalam Chinnathambi; Tahani Awad Alahmadi; Sulaiman Ali Alharbi; Mehdi Shakibaei; Ajaikumar B. Kunnumakkara
Source:
Life sciences 2022 v.293 pp. 120332
ISSN:
0024-3205
Subject:
risk factors,   etc   ; biomarkers; carcinogenesis; interphase; lipids; lung neoplasms; lungs; survival rate; therapeutics; tobacco;     Show all 10 Subjects
Abstract:
... Lung cancer is the foremost cause of cancer related mortality among men and one of the most fatal cancers among women. Notably, the 5-year survival rate of lung cancer is very low; 5% in developing countries. This low survival rate can be attributed to factors like late stage diagnosis, rapid postoperative recurrences in the patients undergoing treatment and development of chemoresistance against ...
DOI:
10.1016/j.lfs.2022.120332

18. PM2.5 exposure inducing ATP alteration links with NLRP3 inflammasome activation [Erratum: April 2022, v.29(17); p.24457]

Author:
Xiang Zeng; Dongling Liu; Weidong Wu; Xia Huo
Source:
Environmental science and pollution research 2022 v.29 no.17 pp. 24445-24456
ISSN:
0944-1344
Subject:
risk factors,   etc   ; COVID-19 infection; adenosine triphosphate; air pollutants; death; inflammasomes; particulates; research;     Show all 8 Subjects
Abstract:
... Fine particulate matter (PM₂.₅) has been the primary air pollutant and the fourth leading risk factor for disease and death in the world. Exposure to PM₂.₅ is related to activation of the NOD-like receptor family pyrin domain containing 3 (NLRP3) inflammasome, but the mechanism of PM₂.₅ affecting the NLRP3 inflammasome is still unclear. Previous studies have shown that PM₂.₅ can cause alterations ...
DOI:
10.1007/s11356-021-16405-w

19. Understanding disease-specific and non-specific factors predicting disordered eating in adults with coeliac disease

Author:
Carley N. Fraser; Stephan P. Möller; Simon R. Knowles
Source:
Appetite 2022 v.168 pp. 105744
ISSN:
0195-6663
Subject:
risk factors,   etc   ; appetite; body mass index; celiac disease; distress; females; gastrointestinal system; surveys;     Show all 8 Subjects
Abstract:
... An adverse relationship between coeliac disease and the development of disordered eating patterns is well established. The aim of this study was to replicate and extend Satherley et al.‘s (2016) study exploring coeliac-specific and non-specific factors predicting disordered eating. An online survey was completed by 187 adults with coeliac disease (90.4% female; Mean age = 48.92; Mean years living ...
DOI:
10.1016/j.appet.2021.105744

20. Use of Eisenia fetida as a Biological Risk Marker in a Qualitative Eco Assessment Test of a Romanian Watercourse

Author:
Romeo T. Cristina; Mihai Baroga; Eugenia Dumitrescu; Florin Muselin; Alexandru O. Doma; Dan Manea; Ioan Banatean-Dunea
Source:
Biology 2022 v.11 no.6 pp. -
ISSN:
2079-7737
Subject:
risk factors,   etc   ; Eisenia fetida; mortality; pollution; rivers; soil; specific growth rate; weight gain;     Show all 8 Subjects
Abstract:
... The qualitative trials were conducted by exposing earthworms to diverse contaminants sources using standard earthworms’ avoidance tests (considered useful ab initio indicators). For two years, we observed the Jiu River pollution points. We observed soil traits in 15 sampling points from two neighboring Romanian counties where Jiu River flows, by evaluating the risk of pollution on Eisenia fetida e ...
DOI:
10.3390/biology11060820