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Nadia Tahtah; Chrystian Zetina-Serrano; Ophélie Rocher; Claire Naylies; Yannick Lippi; André El Khoury; Ali Atoui; Emilien L. Jamin; Isabelle P. Oswald; Sophie Lorber; Olivier Puel
... Penicillium expansum is the main cause of blue mold disease and the main producer of patulin in apple-derived products. This fungus also produces a wide variety of secondary metabolites, including citrinin and chaetoglobosin A. Secondary metabolism is regulated by global transcription factors that are affected by environmental signals. The light-dependent global transcription factor VelB, a member ...
secondarymetabolites, etc ; bioavailability; biomedical research; cosmetics; dietary supplements; food science; health services; human nutrition; humans; industry; innate immunity; markets; mushrooms; polyphenols; Show all 14 Subjects
Abstract:
... Mushrooms are experiencing a kind of renaissance as a part of the contemporary human diet. These valuable organisms are more than food, they fit in perfectly as a novel market group known as nutra-mycoceuticals. Immune-balancing mushroom dietary fibers and secondary metabolites such as polyphenols are the main focus of the healthcare industry. Wellness and cosmetic companies are increasingly using ...
secondarymetabolites, etc ; adenosine triphosphate; amino acid metabolism; biosynthesis; energy; energy metabolism; food chemistry; fruit quality; fruits; mechanical damage; metabolomics; transportation; vibration; Show all 13 Subjects
Abstract:
... Mechanical damage caused by vibration during transportation can destroy organization structure and reduce the fruit quality. The objective was to reveal the mechanism of hypobaric treatment on energy metabolism in vibration-injured 'Huangguan' pears based on metabolomics. Results showed that hypobaric treatment delayed the decline of adenosine triphosphate (ATP) content, energy charge (EC), H⁺-ATP ...
secondarymetabolites, etc ; Botrytis cinerea; Cymbopogon citratus; antifungal properties; cherries; climate; flame ionization; fruits; mass spectrometry; monoterpenoids; mycelium; oils; spore germination; steam distillation; China; Show all 15 Subjects
Abstract:
... Essential oils (EOs) are natural, volatile and aromatic substances extracted from some specific plants. EOs are the secondary metabolite of plants and usually varies with different plants and climate conditions, even in the same plant species but different climate conditions. The antifungal properties of EOs from medicinal as well as other edible plants have been recognized for very long time. Cym ...
secondarymetabolites, etc ; Aspergillus; Penicillium; adsorbents; adsorption; animal and human health; chemiluminescence; coordination polymers; corn; detection limit; fungi; immunosensors; magnetism; ochratoxin A; sorption isotherms; wheat; Show all 16 Subjects
Abstract:
... Ochratoxin A (OTA) is a fungal secondary metabolite produced by certain species of Aspergillus and Penicillium, and is generally found in contaminated grains, presenting considerable risks to human and animal health. Poor stability and insufficient miniaturization of equipment are the two main shortcomings of existing optical biosensors. Herein, we proposed a novel strategy where a magnetic metal- ...
... The doubling of the plant genome causes obvious morphological and physiological changes, and DNA 5-methylcytosine (5mCs) modification is a key epigenetic component that helps neopolyploids overcome challenges and acquire advantages. In the study of autotetraploid grape, we found that leaf thickness, photosynthetic and antioxidant capacity increased and anthocyanin coloring decreased in autotetrapl ...
... Xanthomegnin, a known fungal toxin, secondary metabolite, and pigment diffuses from the dermatophytes has gained attention as local virulence factor because of the mutagenicity, toxicity, cytocidal, and immunosuppressive properties. Not only as a dermatophyte in skin related disorders, the production of xanthomegnin is implicated as a powerful diagnostic marker in patients suffering from ocular my ...
secondarymetabolites, etc ; phosphates; phosphorylation; Show all 3 Subjects
Abstract:
... The phosphate ester is a versatile, widespread functional group involved in a plethora of biological activities. Its presence in secondary metabolites, however, is relatively rare compared to other functionalities and thus is part of a rather unexplored chemical space. Herein, the chemistry of secondary metabolites containing the phosphate ester group is discussed. The text emphasizes their struct ...
... Plants share their natural environment with numerous microorganisms, commensal as well as harmful. Plant fitness and performance are thus dependent on an efficient communication with such microbiota. The primary means of communication are metabolites exuded from roots, primarily diverse secondary metabolites. The exuded metabolites trigger changes in composition and function of plant associated mi ...
secondarymetabolites, etc ; biosynthesis; coculture; fungi; Show all 4 Subjects
Abstract:
... In their natural environment, fungi must compete for resources. It has been hypothesized that this competition likely induces the biosynthesis of secondary metabolites for defence. In a quest to discover new chemical diversity from fungal cultures, a growing trend has been to recapitulate this competitive environment in the laboratory, essentially growing fungi in co-culture. This review covers fu ...
secondarymetabolites, etc ; analytical chemistry; metabolomics; Show all 3 Subjects
Abstract:
... Microbial metabolomics focuses on the analysis of intracellular or extracellular primary metabolites, signaling molecules, hormones, and secondary metabolites, and it is an important field in systems biology. The progress in microbial metabolomics has been slow primarily due to the complexity and diversity of microbial metabolites, which are usually difficult to identify. However, with the rapid d ...
secondarymetabolites, etc ; bioreactors; micropropagation; mists; Show all 4 Subjects
Abstract:
... The temporary immersion systems (TISs) have been widely used in plant biotechnology. TISs have different advantages from the point of micropropagation and production of secondary metabolites over other continuous liquid-phase bioreactors. The current work presents the structure, operation mode, configuration type, and micropropagation or secondary metabolite production in TISs. This review deals w ...
... In this review, we summarized the distribution of the chemically investigated Oceanapia sponges, including the isolation and biological activities of their secondary metabolites, covering the literature from the first report in 1989 to July 2019. There have been 110 compounds reported during this period, including 59 alkaloids, 33 lipids, 14 sterols and 4 miscellaneous compounds. Besides their uni ...
secondarymetabolites, etc ; biosynthesis; enzymes; transcription factors; Show all 4 Subjects
Abstract:
... Plants are a rich source of bioactive compounds, many of which have been exploited for cosmetic, nutritional, and medicinal purposes. Through the characterization of metabolic pathways, as well as the mechanisms responsible for the accumulation of secondary metabolites, researchers have been able to increase the production of bioactive compounds in different plant species for research and commerci ...
secondarymetabolites, etc ; Pseudomonas; Streptomyces; phenazines; soil; Show all 5 Subjects
Abstract:
... Phenazine systems are an important class of aza-polycyclic compounds that are easily found in nature and isolated as secondary metabolites primarily from Pseudomonas, Streptomyces, and a few other genera from soil or marine habitats. Moreover, various synthetic phenazine analogs are known for their pharmaceutical activities. Among various phenazines, benzo[a]phenazines are structural subunits in a ...
secondarymetabolites, etc ; capsaicin; oleuropein; olive oil; Show all 4 Subjects
Abstract:
... Chili olive oil is a popular addition to various foods in many countries. In a detailed study, the content of phenols and capsaicinoids in chili olive oil was determined using chili flakes and whole chilies. A total of 99.8% of the phenols in chili olive oil were secoiridoids, with elenolic acid, oleuropein aglycones, and ligostride aglycones being the most abundant. Chili olive oil with chili fla ...
secondarymetabolites, etc ; adulterants; immunoassays; industry; toxicity; Show all 5 Subjects
Abstract:
... Phytoproducts are involved in various fields of industry. Small-molecule (Mw < 900 Da) organic compounds can be used to indicate the quality of plant samples in the perspective of efficacy by measuring the necessary secondary metabolites and in the perspective of safety by measuring the adulterant level of toxic compounds. The development of reliable detection methods for these compounds in such a ...
secondarymetabolites, etc ; biotechnology; cost effectiveness; lighting; terpenoids; Show all 5 Subjects
Abstract:
... With more than 80 000 compounds, terpenoids represent one of the largest classes of secondary metabolites naturally produced by various plants and other organisms. Owing to the tremendous structural diversity, they offer a wide range of properties relevant for biotechnological and pharmaceutical applications. In this context, heterologous terpenoid production in engineered microbial hosts represen ...
secondarymetabolites, etc ; Nocardiopsis; biosynthesis; medicine; peptides; polyketides; Show all 6 Subjects
Abstract:
... Actinomycetes are currently one of the major sources of bioactive secondary metabolites used for medicine development. Accumulating evidence has shown that Nocardiopsis, a key class of actinomycetes, has the ability to produce novel bioactive natural products. This review covers the sources, distribution, bioactivities, biosynthesis, and structural characteristics of compounds isolated from Nocard ...
secondarymetabolites, etc ; algae; biosynthesis; energy; research; toxicity; Show all 6 Subjects
Abstract:
... Nanoscience has witnessed wide developments in various directions, in addition to its crossing through different vital medical and industrial applications. This prompted the development of green nanotechnology that is environmentally friendly with low toxicity, less energy use, and low eco-hazard. So, algae as green autotrophic organisms, gain increasing attention from nanotechnologists, giving a ...