U.S. flag

An official website of the United States government

Dot gov

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Https

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

PubAg

Main content area

You searched for: Subject "secondary metabolites" Remove constraint Subject: "secondary metabolites"
Start Over

Search

16,695  Search Results

« Previous | 1 - 20 of 16,695 |
Number of results to display per page

Search Results

1. Implication of VelB in the development, pathogenicity, and secondary metabolism of Penicillium expansum

Author:
Nadia Tahtah; Chrystian Zetina-Serrano; Ophélie Rocher; Claire Naylies; Yannick Lippi; André El Khoury; Ali Atoui; Emilien L. Jamin; Isabelle P. Oswald; Sophie Lorber; Olivier Puel
Source:
Postharvest biology and technology 2023 v.195 pp. 112121
ISSN:
0925-5214
Subject:
secondary metabolites,   etc   ; Penicillium expansum; biosynthesis; citrinin; conidiation; ergosterol; genes; molds (fungi); mutants; nitrates; pathogenicity; patulin; siderophores; spores; technology; transcription factors; viability;     Show all 17 Subjects
Abstract:
... Penicillium expansum is the main cause of blue mold disease and the main producer of patulin in apple-derived products. This fungus also produces a wide variety of secondary metabolites, including citrinin and chaetoglobosin A. Secondary metabolism is regulated by global transcription factors that are affected by environmental signals. The light-dependent global transcription factor VelB, a member ...
DOI:
10.1016/j.postharvbio.2022.112121

2. Mushroom β-glucan and polyphenol formulations as natural immunity boosters and balancers: nature of the application

Author:
Maja Kozarski; Anita Klaus; Leo van Griensven; Dragica Jakovljevic; Nina Todorovic; Wan Abd Al Qadr Imad Wan-Mohtar; Jovana Vunduk
Source:
Food science and human wellness 2023 v.12 no.2 pp. 378-396
ISSN:
2213-4530
Subject:
secondary metabolites,   etc   ; bioavailability; biomedical research; cosmetics; dietary supplements; food science; health services; human nutrition; humans; industry; innate immunity; markets; mushrooms; polyphenols;     Show all 14 Subjects
Abstract:
... Mushrooms are experiencing a kind of renaissance as a part of the contemporary human diet. These valuable organisms are more than food, they fit in perfectly as a novel market group known as nutra-mycoceuticals. Immune-balancing mushroom dietary fibers and secondary metabolites such as polyphenols are the main focus of the healthcare industry. Wellness and cosmetic companies are increasingly using ...
DOI:
10.1016/j.fshw.2022.07.040

3. Metabolomics reveals the effect of hypobaric treatment on energy metabolism in vibration-injured ‘Huangguan’ pears

Author:
Fangxu Xu; Guode Li
Source:
Food chemistry 2023 v.400 pp. 134057
ISSN:
0308-8146
Subject:
secondary metabolites,   etc   ; adenosine triphosphate; amino acid metabolism; biosynthesis; energy; energy metabolism; food chemistry; fruit quality; fruits; mechanical damage; metabolomics; transportation; vibration;     Show all 13 Subjects
Abstract:
... Mechanical damage caused by vibration during transportation can destroy organization structure and reduce the fruit quality. The objective was to reveal the mechanism of hypobaric treatment on energy metabolism in vibration-injured 'Huangguan' pears based on metabolomics. Results showed that hypobaric treatment delayed the decline of adenosine triphosphate (ATP) content, energy charge (EC), H⁺-ATP ...
DOI:
10.1016/j.foodchem.2022.134057

4. In vitro and in vivo antifungal activity of Cymbopogon citrates essential oils from different climate conditions against Botrytis cinerea

Author:
Li-Li He; Yun Zhao; Li-Ming Fan; Jun-Jie Zhan; Li-Hong Tao; Yun-Hai Yang; Fa-Wu Su; Qi-Bin Chen; Min Ye
Source:
Scientia horticulturae 2023 v.308 pp. 111544
ISSN:
0304-4238
Subject:
secondary metabolites,   etc   ; Botrytis cinerea; Cymbopogon citratus; antifungal properties; cherries; climate; flame ionization; fruits; mass spectrometry; monoterpenoids; mycelium; oils; spore germination; steam distillation; China;     Show all 15 Subjects
Abstract:
... Essential oils (EOs) are natural, volatile and aromatic substances extracted from some specific plants. EOs are the secondary metabolite of plants and usually varies with different plants and climate conditions, even in the same plant species but different climate conditions. The antifungal properties of EOs from medicinal as well as other edible plants have been recognized for very long time. Cym ...
DOI:
10.1016/j.scienta.2022.111544

5. Combining magnetic MOFs as a highly adsorbent with homogeneous chemiluminescent immunosensor for rapid and ultrasensitive determination of Ochratoxin A

Author:
Qiaoling Wei; Chenxi Huang; Peng Lu; Xiya Zhang; Yiping Chen
Source:
Journal of hazardous materials 2023 v.441 pp. 129960
ISSN:
0304-3894
Subject:
secondary metabolites,   etc   ; Aspergillus; Penicillium; adsorbents; adsorption; animal and human health; chemiluminescence; coordination polymers; corn; detection limit; fungi; immunosensors; magnetism; ochratoxin A; sorption isotherms; wheat;     Show all 16 Subjects
Abstract:
... Ochratoxin A (OTA) is a fungal secondary metabolite produced by certain species of Aspergillus and Penicillium, and is generally found in contaminated grains, presenting considerable risks to human and animal health. Poor stability and insufficient miniaturization of equipment are the two main shortcomings of existing optical biosensors. Herein, we proposed a novel strategy where a magnetic metal- ...
DOI:
10.1016/j.jhazmat.2022.129960

6. Methylome and transcriptome analysis of alters leaf phenotype with autotetraploid in grape

Author:
Xiaodong Xiang; Yukun Gao; Jianghui Cui; Genzeng Ren; Congpei Yin; Jinhua Chang
Source:
Scientia horticulturae 2023 v.307 pp. 111534
ISSN:
0304-4238
Subject:
secondary metabolites,   etc   ; 5-methylcytosine; DNA; Vitis vinifera; anthocyanins; antioxidant activity; autotetraploidy; biosynthesis; bisulfites; cell walls; diploidy; epigenetics; gene expression; gene expression regulation; genomics; grapes; homeostasis; introns; leaf thickness; leaves; lipid metabolism; methylation; phenotype; photosynthesis; plant hormones; transcriptomics;     Show all 26 Subjects
Abstract:
... The doubling of the plant genome causes obvious morphological and physiological changes, and DNA 5-methylcytosine (5mCs) modification is a key epigenetic component that helps neopolyploids overcome challenges and acquire advantages. In the study of autotetraploid grape, we found that leaf thickness, photosynthetic and antioxidant capacity increased and anthocyanin coloring decreased in autotetrapl ...
DOI:
10.1016/j.scienta.2022.111534

7. Ni/Ni(OH)2-rGO nanocomposites sensor for the detection of long forgotten mycotoxin, xanthomegnin

Author:
P.D. Priya Swetha; A. Nikitha; M Manjunath Shenoy; Yoon-Bo Shim; K. Sudhakara Prasad
Source:
Talanta 2023 v.253 pp. 123953
ISSN:
0039-9140
Subject:
secondary metabolites,   etc   ; Aspergillus; Penicillium; Trichophyton rubrum; X-ray photoelectron spectroscopy; death; detection limit; electrochemistry; electron microscopy; energy-dispersive X-ray analysis; glassy carbon electrode; graphene oxide; immunosuppression; keratinophilic fungi; livestock; mutagenicity; mycoses; mycotoxins; nanocomposites; nanoparticles; nickel; ultraviolet-visible spectroscopy; virulence;     Show all 23 Subjects
Abstract:
... Xanthomegnin, a known fungal toxin, secondary metabolite, and pigment diffuses from the dermatophytes has gained attention as local virulence factor because of the mutagenicity, toxicity, cytocidal, and immunosuppressive properties. Not only as a dermatophyte in skin related disorders, the production of xanthomegnin is implicated as a powerful diagnostic marker in patients suffering from ocular my ...
DOI:
10.1016/j.talanta.2022.123953

8. The phosphate ester group in secondary metabolites

Author:
Franco Della-Felice; Aloisio de Andrade Bartolomeu; Ronaldo Aloise Pilli
Source:
Natural product reports 2022 v.39 no.5 pp. 1066-1107
ISSN:
1460-4752
Subject:
secondary metabolites,   etc   ; phosphates; phosphorylation;     Show all 3 Subjects
Abstract:
... The phosphate ester is a versatile, widespread functional group involved in a plethora of biological activities. Its presence in secondary metabolites, however, is relatively rare compared to other functionalities and thus is part of a rather unexplored chemical space. Herein, the chemistry of secondary metabolites containing the phosphate ester group is discussed. The text emphasizes their struct ...
DOI:
10.1039/d1np00078k

9. Plant secondary metabolites altering root microbiome composition and function

Author:
Anna Koprivova; Stanislav Kopriva
Source:
Current opinion in plant biology 2022 v.67 pp. 102227
ISSN:
1369-5266
Subject:
secondary metabolites,   etc   ; microbiome; microorganisms;     Show all 3 Subjects
Abstract:
... Plants share their natural environment with numerous microorganisms, commensal as well as harmful. Plant fitness and performance are thus dependent on an efficient communication with such microbiota. The primary means of communication are metabolites exuded from roots, primarily diverse secondary metabolites. The exuded metabolites trigger changes in composition and function of plant associated mi ...
DOI:
10.1016/j.pbi.2022.102227

10. Fungal–fungal co-culture: a primer for generating chemical diversity

Author:
Sonja L. Knowles; Huzefa A. Raja; Christopher D. Roberts; Nicholas H. Oberlies
Source:
Natural product reports 2022 v.39 no.8 pp. 1557-1573
ISSN:
1460-4752
Subject:
secondary metabolites,   etc   ; biosynthesis; coculture; fungi;     Show all 4 Subjects
Abstract:
... In their natural environment, fungi must compete for resources. It has been hypothesized that this competition likely induces the biosynthesis of secondary metabolites for defence. In a quest to discover new chemical diversity from fungal cultures, a growing trend has been to recapitulate this competitive environment in the laboratory, essentially growing fungi in co-culture. This review covers fu ...
DOI:
10.1039/d1np00070e

11. Microbial metabolomics: From novel technologies to diversified applications

Author:
Dongyang Ye; Xiaowei Li; Jianzhong Shen; Xi Xia
Source:
Trends in analytical chemistry 2022 v.148 pp. 116540
ISSN:
0165-9936
Subject:
secondary metabolites,   etc   ; analytical chemistry; metabolomics;     Show all 3 Subjects
Abstract:
... Microbial metabolomics focuses on the analysis of intracellular or extracellular primary metabolites, signaling molecules, hormones, and secondary metabolites, and it is an important field in systems biology. The progress in microbial metabolomics has been slow primarily due to the complexity and diversity of microbial metabolites, which are usually difficult to identify. However, with the rapid d ...
DOI:
10.1016/j.trac.2022.116540

12. Temporary immersion systems (TISs): A comprehensive review

Author:
Amir Hossein Mirzabe; Ali Hajiahmad; Ali Fadavi; Shahin Rafiee
Source:
Journal of biotechnology 2022 v.357 pp. 56-83
ISSN:
0168-1656
Subject:
secondary metabolites,   etc   ; bioreactors; micropropagation; mists;     Show all 4 Subjects
Abstract:
... The temporary immersion systems (TISs) have been widely used in plant biotechnology. TISs have different advantages from the point of micropropagation and production of secondary metabolites over other continuous liquid-phase bioreactors. The current work presents the structure, operation mode, configuration type, and micropropagation or secondary metabolite production in TISs. This review deals w ...
DOI:
10.1016/j.jbiotec.2022.08.003

13. Secondary Metabolites from Marine Sponges of the Genus Oceanapia: Chemistry and Biological Activities

Author:
Meng-Juan Xu; Lin-Jing Zhong; Jun-Kun Chen; Qing Bu; Lin-Fu Liang
Source:
Marine drugs 2022 v.20 no.2 pp. -
ISSN:
1660-3397
Subject:
secondary metabolites,   etc   ; chemistry; drugs; sterols;     Show all 4 Subjects
Abstract:
... In this review, we summarized the distribution of the chemically investigated Oceanapia sponges, including the isolation and biological activities of their secondary metabolites, covering the literature from the first report in 1989 to July 2019. There have been 110 compounds reported during this period, including 59 alkaloids, 33 lipids, 14 sterols and 4 miscellaneous compounds. Besides their uni ...
DOI:
10.3390/md20020144

14. Application of metabolic engineering to enhance the content of alkaloids in medicinal plants

Author:
Soledad Mora-Vásquez; Guillermo Gael Wells-Abascal; Claudia Espinosa-Leal; Guy A. Cardineau; Silverio García-Lara
Source:
Metabolic Engineering Communications 2022 v.14 pp. e00194
ISSN:
2214-0301
Subject:
secondary metabolites,   etc   ; biosynthesis; enzymes; transcription factors;     Show all 4 Subjects
Abstract:
... Plants are a rich source of bioactive compounds, many of which have been exploited for cosmetic, nutritional, and medicinal purposes. Through the characterization of metabolic pathways, as well as the mechanisms responsible for the accumulation of secondary metabolites, researchers have been able to increase the production of bioactive compounds in different plant species for research and commerci ...
DOI:
10.1016/j.mec.2022.e00194

15. A review on lawsone-based benzo[a]phenazin-5-ol: synthetic approaches and reactions

Author:
Abolfazl Olyaei; Mahdieh Sadeghpour
Source:
RSC advances 2022 v.12 no.22 pp. 13837-13895
ISSN:
2046-2069
Subject:
secondary metabolites,   etc   ; Pseudomonas; Streptomyces; phenazines; soil;     Show all 5 Subjects
Abstract:
... Phenazine systems are an important class of aza-polycyclic compounds that are easily found in nature and isolated as secondary metabolites primarily from Pseudomonas, Streptomyces, and a few other genera from soil or marine habitats. Moreover, various synthetic phenazine analogs are known for their pharmaceutical activities. Among various phenazines, benzo[a]phenazines are structural subunits in a ...
DOI:
10.1039/d2ra02139k

16. Characterization and Quantification of Capsaicinoids and Phenolic Compounds in Two Types of Chili Olive Oils, Using HPLC/MS

Author:
Tilen Zamljen; Ana Slatnar; Metka Hudina; Robert Veberic; Aljaž Medic
Source:
Foods 2022 v.11 no.15 pp. -
ISSN:
2304-8158
Subject:
secondary metabolites,   etc   ; capsaicin; oleuropein; olive oil;     Show all 4 Subjects
Abstract:
... Chili olive oil is a popular addition to various foods in many countries. In a detailed study, the content of phenols and capsaicinoids in chili olive oil was determined using chili flakes and whole chilies. A total of 99.8% of the phenols in chili olive oil were secoiridoids, with elenolic acid, oleuropein aglycones, and ligostride aglycones being the most abundant. Chili olive oil with chili fla ...
DOI:
10.3390/foods11152256

17. Lateral flow immunoassay for small-molecules detection in phytoproducts: a review

Author:
Poomraphie Nuntawong; Waraporn Putalun; Hiroyuki Tanaka; Satoshi Morimoto; Seiichi Sakamoto
Source:
Natural medicines 2022 v.76 no.3 pp. 521-545
ISSN:
1340-3443
Subject:
secondary metabolites,   etc   ; adulterants; immunoassays; industry; toxicity;     Show all 5 Subjects
Abstract:
... Phytoproducts are involved in various fields of industry. Small-molecule (Mw < 900 Da) organic compounds can be used to indicate the quality of plant samples in the perspective of efficacy by measuring the necessary secondary metabolites and in the perspective of safety by measuring the adulterant level of toxic compounds. The development of reliable detection methods for these compounds in such a ...
DOI:
10.1007/s11418-022-01605-6

18. Engineering phototrophic bacteria for the production of terpenoids

Author:
Oliver Klaus; Fabienne Hilgers; Andreas Nakielski; Dennis Hasenklever; Karl-Erich Jaeger; Ilka M Axmann; Thomas Drepper
Source:
Current opinion in biotechnology 2022 v.77 pp. 102764
ISSN:
0958-1669
Subject:
secondary metabolites,   etc   ; biotechnology; cost effectiveness; lighting; terpenoids;     Show all 5 Subjects
Abstract:
... With more than 80 000 compounds, terpenoids represent one of the largest classes of secondary metabolites naturally produced by various plants and other organisms. Owing to the tremendous structural diversity, they offer a wide range of properties relevant for biotechnological and pharmaceutical applications. In this context, heterologous terpenoid production in engineered microbial hosts represen ...
DOI:
10.1016/j.copbio.2022.102764

19. Genus Nocardiopsis: A Prolific Producer of Natural Products

Author:
Ting Shi; Yi-Fei Wang; Han Wang; Bo Wang
Source:
Marine drugs 2022 v.20 no.6 pp. -
ISSN:
1660-3397
Subject:
secondary metabolites,   etc   ; Nocardiopsis; biosynthesis; medicine; peptides; polyketides;     Show all 6 Subjects
Abstract:
... Actinomycetes are currently one of the major sources of bioactive secondary metabolites used for medicine development. Accumulating evidence has shown that Nocardiopsis, a key class of actinomycetes, has the ability to produce novel bioactive natural products. This review covers the sources, distribution, bioactivities, biosynthesis, and structural characteristics of compounds isolated from Nocard ...
DOI:
10.3390/md20060374

20. The efficient role of algae as green factories for nanotechnology and their vital applications

Author:
Mostafa M. El-Sheekh; Hanaa H. Morsi; Lamiaa H.S. Hassan; Sameh S. Ali
Source:
Microbiological research 2022 v.263 pp. 127111
ISSN:
0944-5013
Subject:
secondary metabolites,   etc   ; algae; biosynthesis; energy; research; toxicity;     Show all 6 Subjects
Abstract:
... Nanoscience has witnessed wide developments in various directions, in addition to its crossing through different vital medical and industrial applications. This prompted the development of green nanotechnology that is environmentally friendly with low toxicity, less energy use, and low eco-hazard. So, algae as green autotrophic organisms, gain increasing attention from nanotechnologists, giving a ...
DOI:
10.1016/j.micres.2022.127111