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1. Different methods for diagnosis of sarcopenia and its association with nutritional status and survival in patients with advanced cancer in palliative care

Author:
da Silva, Jaqueline Rodrigues; Wiegert, Emanuelly Varea Maria; Oliveira, Livia; Calixto-Lima, Larissa
Source:
Nutrition 2019 v.60 pp. 48-52
ISSN:
0899-9007
Subject:
skeletal muscle,   etc   ; calf circumference; malnutrition; mortality; muscles; neoplasms; nutritional status; patients; prospective studies; regression analysis; sarcopenia;     Show all 11 Subjects
Abstract:
... The aim of the present study was to evaluate the association between sarcopenia, diagnosed by different muscle mass measurement techniques, with nutritional status and overall survival in patients with advanced cancer under palliative care.To investigate the association of sarcopenia, according to distinct muscle mass measurement methods, with nutritional status and overall survival (OS).This obse ...
DOI:
10.1016/j.nut.2018.09.003

2. Body composition evaluation with computed tomography: Contrast media and slice thickness cause methodological errors

Author:
Morsbach, Fabian; Zhang, Yi-Hua; Martin, Lena; Lindqvist, Catarina; Brismar, Torkel
Source:
Nutrition 2019 v.59 pp. 50-55
ISSN:
0899-9007
Subject:
skeletal muscle,   etc   ; abdomen; adipose tissue; body composition; computed tomography; hepatoma; image analysis; muscles; patients; protocols; women;     Show all 11 Subjects
Abstract:
... Although computed tomography (CT) is frequently used to determine body composition, the effects of using different CT protocols is not well known. The aim of this study was to determine whether contrast media phase, radiation dose, and slice thickness in CT affect body composition segmentation.Clinically indicated perfusion CTs of the upper abdomen in 20 patients (seven women) between 40 and 87 y ...
DOI:
10.1016/j.nut.2018.08.001

3. Comparison of computed tomographic attenuation values for epaxial muscles in old and young dogs

Author:
Sutherland-Smith, James; Hutchinson, Dana; Freeman, Lisa M.
Source:
American journal of veterinary research 2019 v.80 no.2 pp. 174-177
ISSN:
0002-9645
Subject:
skeletal muscle,   etc   ; Labrador Retriever; body condition; computed tomography; computer software; data collection; dogs; lipid content; muscles;     Show all 9 Subjects
Abstract:
... OBJECTIVE To determine whether the degree of CT attenuation of muscle would differ between healthy old and young dogs. ANIMALS 10 healthy old (> 8 years old) and 9 healthy young (1 to 5 years old) Labrador Retrievers with a body condition score of 5 or 6 on a 9-point scale. PROCEDURES CT was performed with the dogs mildly sedated. A freehand closed polygon tool was used to define the outer margin ...
DOI:
10.2460/ajvr.80.2.174

4. Effects of a leucine-enriched amino acid supplement on muscle mass, muscle strength, and physical function in post-stroke patients with sarcopenia: A randomized controlled trial

Author:
Yoshimura, Yoshihiro; Bise, Takahiro; Shimazu, Sayuri; Tanoue, Maiko; Tomioka, Yuko; Araki, Mai; Nishino, Takafumi; Kuzuhara, Aomi; Takatsuki, Fumihiko
Source:
Nutrition 2019 v.58 pp. 1-6
ISSN:
0899-9007
Subject:
skeletal muscle,   etc   ; amino acids; muscle strength; muscles; patients; randomized clinical trials; sarcopenia; strength training;     Show all 8 Subjects
Abstract:
... The aim of this study was to investigate the effects of a leucine-enriched amino acid supplement on muscle mass, muscle strength, and physical function in post-stroke patients with sarcopenia.We conducted an eight-wk, two-parallel group intervention, randomized controlled, blinded outcome assessment among 44 post-stroke older patients with sarcopenia. Sarcopenia was defined as a loss of skeletal m ...
DOI:
10.1016/j.nut.2018.05.028

5. Electrochemiluminescence Investigation of Glucose Transporter 4 Expression at Skeletal Muscle Cells Surface Based on a Graphene Hydrogel Electrode

Author:
Liu, Gen; Ma, Cheng; Jin, Bao-Kang; Chen, Zixuan; Cheng, Fa-Liang; Zhu, Jun-Jie
Source:
Analytical chemistry 2019 v.91 no.4 pp. 3021-3026
ISSN:
1520-6882
Subject:
skeletal muscle,   etc   ; carbon quantum dots; disease diagnosis; electrochemiluminescence; electrodes; glucose transporters; graphene; hydrogels; insulin; myocytes; receptors;     Show all 11 Subjects
Abstract:
... In situ detection of the expression level of cell-surface receptors has become a hotspot study in recent years. We propose in this manuscript a novel strategy for sensitive electrochemiluminescence (ECL) detection of glucose transporter 4 (GLUT4) on human skeletal muscle cells (HSMCs). Graphene hydrogel (GH) was selected to fabricate a permeable electrode with the purpose of overcoming the steric ...
DOI:
10.1021/acs.analchem.8b05340

6. A comparison of two different software packages for analysis of body composition using computed tomography images

Author:
Rollins, Katie E; Awwad, Amir; Macdonald, Ian A.; Lobo, Dileep N.
Source:
Nutrition 2019 v.57 pp. 92-96
ISSN:
0899-9007
Subject:
skeletal muscle,   etc   ; computed tomography; computer software; image analysis; lean body mass; patients; Canada; Switzerland;     Show all 8 Subjects
Abstract:
... The analysis of body composition from computed tomography (CT) imaging has become widespread. However, the methodology used is far from established. Two main software packages are commonly used for body composition analysis, with results used interchangeably. However, the equivalence of these has not been well established. The aim of this study was to compare the results of body composition analys ...
DOI:
10.1016/j.nut.2018.06.003

7. A Zfp609 circular RNA regulates myoblast differentiation by sponging miR-194-5p

Author:
Wang, YanHong; Li, MengLu; Wang, YanHuan; Liu, Jia; Zhang, MoLan; Fang, XingTang; Chen, Hong; Zhang, ChunLei
Source:
International journal of biological macromolecules 2019 v.121 pp. 1308-1313
ISSN:
0141-8130
Subject:
skeletal muscle,   etc   ; binding sites; breeding; cell lines; chemical bonding; luciferase; mice; microRNA; muscle development; myoblasts; screening;     Show all 11 Subjects
Abstract:
... Skeletal muscle development and growth regulatory mechanism is the focus of both animal genetics and medicine. The recent studies indicate that covalently closed circular RNAs (circRNAs) also play important role on muscle development through sequestering specific miRNAs. The present study was conducted to determine the functional roles of circZfp609, a recently identified circRNA, in the regulatio ...
DOI:
10.1016/j.ijbiomac.2018.09.039

8. Guanidinoacetic acid with creatine compared with creatine alone for tissue creatine content, hyperhomocysteinemia, and exercise performance: A randomized, double-blind superiority trial

Author:
Semeredi, Sasa; Stajer, Valdemar; Ostojic, Jelena; Vranes, Milan; Ostojic, Sergej M.
Source:
Nutrition 2019 v.57 pp. 162-166
ISSN:
0899-9007
Subject:
skeletal muscle,   etc   ; biomarkers; blood serum; brain; creatine; energy metabolism; exercise; men; oral administration; weight gain;     Show all 10 Subjects
Abstract:
... Co-administration of creatine and guanidinoacetic acid (GAA) has been recently put forward as an advanced dietary strategy to optimize tissue bioenergetics. We hypothesized that creatine-GAA mixture would result in a more powerful rise in brain and skeletal muscle creatine, as compared to creatine supplementation alone.A randomized, double-blinded, crossover superiority trial has been performed at ...
DOI:
10.1016/j.nut.2018.04.009

9. Mitochondrial breakdown in skeletal muscle and the emerging role of the lysosomes

Author:
Triolo, Matthew; Hood, David A.
Source:
Archives of biochemistry and biophysics 2019 v.661 pp. 66-73
ISSN:
0003-9861
Subject:
skeletal muscle,   etc   ; biogenesis; energy; exercise; locomotion; lysosomes; mitochondria; mitophagy; myocytes; therapeutics;     Show all 10 Subjects
Abstract:
... Skeletal muscle mitochondria are essential in providing the energy required for locomotion. In response to contractile activity, the production of mitochondria is upregulated to meet the energy demands placed upon muscle cells. In a coordinated fashion, exercise also promotes the breakdown of dysfunctional mitochondria via mitophagy. Mitophagy is characterized by the selection of poorly functionin ...
DOI:
10.1016/j.abb.2018.11.004

10. The differential proliferation and differentiation ability of skeletal muscle satellite cell in Boer and Nanjiang brown goats

Author:
Zhao, Wei; Chen, Li; Zhong, Tao; Wang, Linjie; Guo, Jiazhong; Dong, Yao; Feng, Jing; Song, Tianzeng; Li, Li; Zhang, Hongping
Source:
Small ruminant research 2018 v.169 pp. 99-107
ISSN:
0921-4488
Subject:
skeletal muscle,   etc   ; Boer (goat breed); goats; muscles;     Show all 4 Subjects
Abstract:
... Here, for the first time, we analyzed skeletal muscle morphology in Boer and Nanjiang Brown (NJ) goats and then evaluated the differences in skeletal muscle satellite cells (SMSCs) proliferation and differentiation ability between the two breeds. Our results revealed that NJ goats had significantly more myofiber cells and a significantly smaller cross-section area compared with the Boer goats (P < ...
DOI:
10.1016/j.smallrumres.2018.07.006

11. β-hydroxy-β-methylbutyrate (HMB) improves mitochondrial function in myocytes through pathways involving PPARβ/δ and CDK4

Author:
Zhong, Yinzhao; Zeng, Liming; Deng, Jinping; Duan, Yehui; Li, Fengna
Source:
Nutrition 2019 v.60 pp. 217-226
ISSN:
0899-9007
Subject:
skeletal muscle,   etc   ; antagonists; biogenesis; butyrates; essential amino acids; gene expression; leucine; messenger RNA; metabolic diseases; metabolites; mitochondria; myotubes; obesity;     Show all 13 Subjects
Abstract:
... Mitochondrial dysfunction in skeletal muscle has emerged as key to the development of obesity and its related metabolic disorders. Leucine (Leu) is an essential amino acid that has been reported to increase mitochondrial biogenesis in muscle cells, as has its metabolite β-hydroxy-β-methylbutyrate (HMB). However, two questions—which one is more potent and what is the cellular mechanisms of the acti ...
DOI:
10.1016/j.nut.2018.09.032

12. Vitamin D, muscle recovery, sarcopenia, cachexia, and muscle atrophy

Author:
Garcia, Matheus; Seelaender, Marilia; Sotiropoulos, Athanassia; Coletti, Dario; Lancha, Antonio Herbert
Source:
Nutrition 2019 v.60 pp. 66-69
ISSN:
0899-9007
Subject:
skeletal muscle,   etc   ; cachexia; calcitriol receptors; genomics; hypertrophy; in vivo studies; metabolism; muscle fibers; muscles; sarcopenia; vitamin D;     Show all 11 Subjects
Abstract:
... The relevance of vitamin D to skeletal muscle metabolism has been highlighted in recent years. The interest arises from the important findings of studies demonstrating multiple effects of vitamin D on this tissue, which can be divided into genomic (direct effects) and non-genomic effects (indirect effects). Another important aspect to be considered in the study of vitamin D and muscle fiber metabo ...
DOI:
10.1016/j.nut.2018.09.031

13. Mitochondrial dysfunction induces muscle atrophy during prolonged inactivity: A review of the causes and effects

Author:
Hyatt, Hayden; Deminice, Rafael; Yoshihara, Toshinori; Powers, Scott K.
Source:
Archives of biochemistry and biophysics 2019 v.662 pp. 49-60
ISSN:
0003-9861
Subject:
skeletal muscle,   etc   ; animal injuries; calcium; mitochondria; morbidity; mortality; muscles; muscular atrophy; patients; phenotype; proteolysis; quality of life; risk; spinal cord;     Show all 14 Subjects
Abstract:
... Prolonged skeletal muscle inactivity (e.g. limb immobilization, bed rest, mechanical ventilation, spinal cord injury, etc.) results in muscle atrophy that manifests into a decreased quality of life and in select patient populations, a higher risk of morbidity and mortality. Thus, understanding the processes that contribute to muscle atrophy during prolonged periods of muscle disuse is an important ...
DOI:
10.1016/j.abb.2018.11.005

14. Perfusion-weighted and diffusion-weighted magnetic resonance imaging of the liver, spleen, and kidneys of healthy adult male cats

Author:
Del Chicca, Francesca; Salesov, Elena; Joerger, Fabiola; Richter, Henning; Reusch, Claudia E.; Kircher, Patrick R.
Source:
American journal of veterinary research 2019 v.80 no.2 pp. 159-167
ISSN:
0002-9645
Subject:
skeletal muscle,   etc   ; abdomen; adults; cats; cortex; diffusivity; kidneys; liver; magnetic resonance imaging; males; parenchyma (animal tissue); spleen;     Show all 12 Subjects
Abstract:
... OBJECTIVE To describe perfusion and diffusion characteristics of the liver, spleen, and kidneys of healthy adult male cats as determined by morphological, perfusion-weighted, and diffusion-weighted MRI. ANIMALS 12 healthy adult male cats. PROCEDURES Each cat was anesthetized. Morphological, perfusion-weighted, and diffusion-weighted MRI of the cranial aspect of the abdomen was performed. A region ...
DOI:
10.2460/ajvr.80.2.159

15. Anthocyanins from dietary black soybean potentiate glucose uptake in L6 rat skeletal muscle cells via up-regulating phosphorylated Akt and GLUT4

Author:
Chen, Zhongqin; Li, Weiwei; Guo, Qingwen; Xu, Leilei; Santhanam, Ramesh Kumar; Gao, Xudong; Chen, Yue; Wang, Chunli; Panichayupakaranant, Pharkphoom; Chen, Haixia
Source:
Journal of functional foods 2019 v.52 pp. 663-669
ISSN:
1756-4646
Subject:
skeletal muscle,   etc   ; anthocyanins; functional foods; glucose; glucose transporters; medicine; metabolic diseases; myotubes; rats; seed coat; signal transduction; soybeans;     Show all 12 Subjects
Abstract:
... In order to illustrate the hypoglycemic mechanism of the dietary anthocyanins from black soybean, the effects of black soybean seed coat extract (BSSCE) and cyanidin-3-O-glucoside (Cy3G), the major anthocyanins of BSSCE on regulation of Akt and GLUT4 in L6 rat skeletal muscle cells were studied. BSSCE and Cy3G significantly augmented the glucose uptake in L6 myotubes in comparison to the normal co ...
DOI:
10.1016/j.jff.2018.11.049

16. Associations between Sarcopenic Obesity and Cognitive Impairment in Elderly Chinese Community-Dwelling Individuals

Author:
Wang, H.; Hai, S.; Liu, Y. X.; Cao, L.; Liu, Y.; Liu, P.; Yang, Y.; Dong, Birong
Source:
The journal of nutrition, health & aging 2019 v.23 no.1 pp. 14-20
ISSN:
1279-7707
Subject:
skeletal muscle,   etc   ; Chinese people; cognitive disorders; confidence interval; elderly; gender; men; models; obesity; odds ratio; sarcopenia; statistical analysis; women;     Show all 13 Subjects
Abstract:
... INTRODUCTION: This study aimed to estimate the prevalence of sarcopenic obesity (SO) and the association between cognitive impairment and SO in a cohort of elderly Chinese community-dwelling individuals. METHODS: A total of 948 elderly Chinese community-dwelling individuals aged 60–92 years were recruited. The participants were categorized into the following four groups according to their sarcopen ...
DOI:
10.1007/s12603-018-1088-3

17. Associations of Skeletal Muscle Mass, Lower-Extremity Functioning, and Cognitive Impairment in Community-Dwelling Older People in Japan

Author:
Ishii, Hideaki; Makizako, H.; Doi, T.; Tsutsumimoto, K.; Shimada, H.
Source:
The journal of nutrition, health & aging 2019 v.23 no.1 pp. 35-41
ISSN:
1279-7707
Subject:
skeletal muscle,   etc   ; Japanese people; bioelectrical impedance; cognition; cognitive disorders; comorbidity; confidence interval; elderly; memory; models; odds ratio; regression analysis; Japan;     Show all 13 Subjects
Abstract:
... OBJECTIVE: We examined whether skeletal muscle mass and lower extremity functioning are closely associated with multiple cognitive domains, including global cognition, memory, attention, executive functioning, and processing speed, in community-dwelling older Japanese adults. DESIGN: A cross-sectional, population-based community study. SETTING: This study was conducted among community-living older ...
DOI:
10.1007/s12603-018-1110-9

18. Cleavage of loops 1 and 2 in skeletal muscle heavy meromyosin (HMM) leads to a decreased function

Author:
Cheng, Yu-Shu; Matusovskiy, Oleg S.; Rassier, Dilson E.
Source:
Archives of biochemistry and biophysics 2019 v.661 pp. 168-177
ISSN:
0003-9861
Subject:
skeletal muscle,   etc   ; actin; adenosine triphosphate; adenosinetriphosphatase; amino acid sequences; breathing; enzyme activity; heavy meromyosin; locomotion; mass spectrometry; microfilaments; proteolysis; rabbits;     Show all 13 Subjects
Abstract:
... The mechanical work and the actin-activated ATP kinetics in skeletal muscles are closely associated with two surface loops that are present in the myosin molecule: loop 1 and loop 2. They are located close to the ATP-loop (loop 1), and the actin binding domain (loop 2). In this study we investigated the roles of loops 1 and 2 in the regulation of the load-dependent velocity of actin sliding and AT ...
DOI:
10.1016/j.abb.2018.11.002

19. Oxytocin is involved in steroid hormone–stimulated bovine satellite cell proliferation and differentiation in vitro

Author:
Zhang, Zhenhe; Zhao, Lidan D.; Johnson, Sally E.; Rhoads, Michelle L.; Jiang, Honglin; Rhoads, Robert P.
Source:
Domestic animal endocrinology 2019 v.66 pp. 1-13
ISSN:
0739-7240
Subject:
skeletal muscle,   etc   ; apoptosis; cattle; cell proliferation; estradiol; hypertrophy; livestock and meat industry; muscles; oxytocin; steroid hormones; tamoxifen; trenbolone;     Show all 12 Subjects
Abstract:
... Sex steroid hormones are used in the meat industry due to their ability to regulate muscle hypertrophy. However, the mechanisms underlying their action are not fully elucidated. Recent reports demonstrate that steroid hormones increase oxytocin (OXT) expression in skeletal muscle, indicating that OXT may play a role in satellite cell activity. This hypothesis was tested using steroid hormones (17β ...
DOI:
10.1016/j.domaniend.2018.07.003

20. Effects of functional β-glucan on proliferation, differentiation, metabolism and its anti-fibrosis properties in muscle cells

Author:
Li, Yan; Fan, Yihui; Pan, Haiou; Qian, Haifeng; Qi, Xiguang; Wu, Gangcheng; Zhang, Hui; Xu, Meijuan; Rao, Zhiming; Wang, Li; Ying, Hao
Source:
International journal of biological macromolecules 2018 v.117 pp. 287-293
ISSN:
0141-8130
Subject:
skeletal muscle,   etc   ; aerobiosis; beta-glucans; muscle fibers; myoblasts; myotubes; therapeutics;     Show all 7 Subjects
Abstract:
... Skeletal muscles plays a crucial role in metabolism and exercise. Fuctional β-glucan is polysaccharide that is found in the cell walls of cereal, which is known to reduce cholesterol and lipid, prevent diabetes, cancer and cardiovascular diseases. In an attempt to identify β-glucan that could promote skeletal muscle function, we analyzed the proliferation, differentiation, metabolism and anti-fibr ...
DOI:
10.1016/j.ijbiomac.2018.05.188