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1. Correction: Hydrogel microfibers with perfusable folded channels for tissue constructs with folded morphology

Author:
Liu, Yupeng; Xu, Peidi; Liang, Zhe; Xie, Ruoxiao; Ding, Mingyu; Liu, Hongxia; Liang, Qionglin
Source:
RSC advances 2019 v.9 no.19 pp. 10625
ISSN:
2046-2069
Subject:
skeletal muscle,   etc   ; endoderm; hydrogels; intestines; tissue engineering;     Show all 5 Subjects
Abstract:
... Correction for ‘Hydrogel microfibers with perfusable folded channels for tissue constructs with folded morphology’ by Yupeng Liu et al., RSC Adv., 2018, 8, 23475–23480. ...
DOI:
10.1039/c9ra90025j

2. Structural Basis for the Distinct Membrane Binding Activity of the Homologous C2A Domains of Myoferlin and Dysferlin

Author:
Harsini, Faraz M.; Bui, Anthony A.; Rice, Anne M.; Chebrolu, Sukanya; Fuson, Kerry L.; Turtoi, Andrei; Bradberry, Mazdak; Chapman, Edwin R.; Sutton, R. Bryan
Source:
Journal of molecular biology 2019 v.431 no.11 pp. 2112-2126
ISSN:
0022-2836
Subject:
skeletal muscle,   etc   ; calcium; cations; crystal structure; humans; myoblasts; phosphatidylserines; proteins;     Show all 8 Subjects
Abstract:
... Dysferlin has been implicated in acute membrane repair processes, whereas myoferlin's activity is maximal during the myoblast fusion stage of early skeletal muscle cell development. Both proteins are similar in size and domain structure; however, despite the overall similarity, myoferlin's known physiological functions do not overlap with those of dysferlin. Here we present for the first time the ...
DOI:
10.1016/j.jmb.2019.04.006

3. INSL3 in the muscolo-skeletal system

Author:
De Toni, Luca; Agoulnik, Alexander I.; Sandri, Marco; Foresta, Carlo; Ferlin, Alberto
Source:
Molecular and cellular endocrinology 2019 v.487 pp. 12-17
ISSN:
0303-7207
Subject:
skeletal muscle,   etc   ; hormonal regulation; muscles; peptides; phenotype; testes; testosterone; therapeutics;     Show all 8 Subjects
Abstract:
... Bone and skeletal muscle are currently considered a unified functional unit, showing complementary regulation at mechanical, biochemical, paracrine and metabolic levels. This functional unit undergoes a central hormonal regulation which is mainly ascribed to sex steroids and, in particular, androgens. However, recent evidence suggest that another testicular hormone lines the classical anabolic eff ...
DOI:
10.1016/j.mce.2018.12.021

4. Energy-dissipating hub in muscle mitochondria: Potassium channels and uncoupling proteins

Author:
Jarmuszkiewicz, Wieslawa; Szewczyk, Adam
Source:
Archives of biochemistry and biophysics 2019 v.664 pp. 102-109
ISSN:
0003-9861
Subject:
skeletal muscle,   etc   ; energy; homeostasis; mitochondria; muscles; myocardium; potassium channels;     Show all 7 Subjects
Abstract:
... Energy homeostasis in mitochondria is vital for proper muscle cell function. In this review we will focus on cardiac and skeletal muscle energy-dissipating systems, i.e., mitochondrial potassium channels and uncoupling proteins. Despite the molecular differences between these proteins both of them may regulate the generation of reactive oxygen species. Hence, they can both modulate pro-life and -d ...
DOI:
10.1016/j.abb.2019.01.036

5. Prevalance of sarcopenia according to decade

Author:
Yazar, Tamer; Olgun Yazar, Hülya
Source:
Clinical nutrition ESPEN 2019 v.29 pp. 137-141
ISSN:
2405-4577
Subject:
skeletal muscle,   etc   ; elderly; females; males; muscles; sarcopenia; volunteers; walking;     Show all 8 Subjects
Abstract:
... Our study aimed to identify Skeletal Muscle Mass Index (SMMI) cut-off values for sarcopenia diagnosis in our population and determine the prevalance of sarcopenia, and to collect data about reducing the disease load.The study was completed with 515 volunteers divided into groups based on ages of 18–39 years, 40–49 years, 50–59 years, 60–69 years, 70–79 years and 80 years and older. All groups had ...
DOI:
10.1016/j.clnesp.2018.11.005

6. TBC1D15 affects glucose uptake by regulating GLUT4 translocation

Author:
Wu, Jia; Cheng, Dandan; Liu, Li; Lv, Zhengbing; Liu, Kuancheng
Source:
Gene 2019 v.683 pp. 210-215
ISSN:
0378-1119
Subject:
skeletal muscle,   etc   ; cell membranes; glucose; glucose transporters; lysosomes;     Show all 5 Subjects
Abstract:
... Glucose transport into skeletal muscle is mediated by the principal glucose transporter protein, GLUT4, which can be transported from intracellular vesicles to the cytoplasmic membrane, and the translocation of GLUT4 vesicles requires a variety of Rab proteins. Previously we reported a new type of TBC1D15 from C. plagiosum with Rab-GAP activity for Rab7. Here we reported that TBC1D15 regulated glu ...
DOI:
10.1016/j.gene.2018.10.025

7. Structural and functional properties of αβ-heterodimers of tropomyosin with myopathic mutations Q147P and K49del in the β-chain

Author:
Matyushenko, Alexander M.; Shchepkin, Daniil V.; Susorov, Denis S.; Nefedova, Victoria V.; Kopylova, Galina V.; Berg, Valentina Y.; Kleymenov, Sergey Y.; Levitsky, Dmitrii I.
Source:
Biochemical and biophysical research communications 2019 v.508 no.3 pp. 934-939
ISSN:
0006-291X
Subject:
skeletal muscle,   etc   ; functional properties; humans; models; mutation; tropomyosins;     Show all 6 Subjects
Abstract:
... Tropomyosin (Tpm) is an α-helical coiled-coil actin-binding protein that plays a key role in the Ca2+-regulated contraction of striated muscles. Two Tpm isoforms, α (Tpm 1.1) and β (Tpm 2.2), are expressed in fast skeletal muscles. These Tpm isoforms can form either αα and ββ homodimers, or αβ heterodimers. However, only αα-Tpm and αβ-Tpm dimers are usually present in most of fast skeletal muscles ...
DOI:
10.1016/j.bbrc.2018.12.019

8. A kinetic model of carnosine synthesis in human skeletal muscle

Author:
Spelnikov, Dmitry; Harris, Roger Charles
Source:
Amino acids 2019 v.51 no.1 pp. 115-121
ISSN:
0939-4451
Subject:
skeletal muscle,   etc   ; carnosine; equations; humans; kinetics; mathematical models; muscles;     Show all 7 Subjects
Abstract:
... Drawing on previously published data, a mathematical model is proposed to describe the synthesis of carnosine in muscle using a slow release β-alanine supplement (SR-CarnoSyn®). The model pre-supposes that the rate of synthesis for any given dose of β-alanine (within the range 1.6–6.4 g day⁻¹) is constant with time, but is first order with respect to daily β-alanine dose. Simultaneously with synth ...
DOI:
10.1007/s00726-018-2646-z

9. Perivascular cell αv integrins as a target to treat skeletal muscle fibrosis

Author:
Prazeres, Pedro H.D.M.; Turquetti, Anaelise O.M.; Azevedo, Patrick O.; Barreto, Rodrigo S.N.; Miglino, Maria A.; Mintz, Akiva; Delbono, Osvaldo; Birbrair, Alexander
Source:
The international journal of biochemistry & cell biology 2018 v.99 pp. 109-113
ISSN:
1357-2725
Subject:
skeletal muscle,   etc   ; fibrosis; integrins; muscles;     Show all 4 Subjects
Abstract:
... Fibrosis following injury leads to aberrant regeneration and incomplete functional recovery of skeletal muscle, but the lack of detailed knowledge about the cellular and molecular mechanisms involved hampers the design of effective treatments. Using state-of-the-art technologies, Murray et al. (2017) found that perivascular PDGFRβ-expressing cells generate fibrotic cells in the skeletal muscle. St ...
DOI:
10.1016/j.biocel.2018.04.002

10. Prion protein polymorphisms associated with reduced CWD susceptibility limit peripheral PrPCWD deposition in orally infected white-tailed deer

Author:
Otero, Alicia; Duque Velásquez, Camilo; Johnson, Chad; Herbst, Allen; Bolea, Rosa; Badiola, Juan José; Aiken, Judd; McKenzie, Debbie
Source:
BMC veterinary research 2019 v.15 no.1 pp. 50
ISSN:
1746-6148
Subject:
skeletal muscle,   etc   ; Odocoileus virginianus; alleles; brain; chronic wasting disease; deer; genotype; immunohistochemistry; pathogens; prions;     Show all 10 Subjects
Abstract:
... BACKGROUND: Chronic wasting disease (CWD) is a prion disease affecting members of the Cervidae family. PrPC primary structures play a key role in CWD susceptibility resulting in extended incubation periods and regulating the propagation of CWD strains. We analyzed the distribution of abnormal prion protein (PrPCᵂᴰ) aggregates in brain and peripheral organs from orally inoculated white-tailed deer ...
DOI:
10.1186/s12917-019-1794-z

11. Highly photostable two-photon NIR AIEgens with tunable organelle specificity and deep tissue penetration

Author:
Niu, Guangle; Zhang, Ruoyao; Gu, Yuan; Wang, Jianguo; Ma, Chao; Kwok, Ryan T.K.; Lam, Jacky W.Y.; Sung, Herman H.-Y.; Williams, Ian D.; Wong, Kam Sing; Yu, Xiaoqiang; Tang, Ben Zhong
Source:
Biomaterials 2019 v.208 pp. 72-82
ISSN:
0142-9612
Subject:
skeletal muscle,   etc   ; biocompatibility; fluorescence; fluorescent dyes; image analysis; irradiation; mitochondria; photobleaching; photostability; rats; staining;     Show all 11 Subjects
Abstract:
... Photostability is a particularly important parameter for fluorescence imaging especially long-term dynamic tracking in live samples. However, many organic fluorophores show poor photostability under one-photon and two-photon continuous irradiation. In addition, these traditional fluorophores also suffer from aggregation-caused quenching (ACQ) in aggregate state in insolvable water environment. The ...
DOI:
10.1016/j.biomaterials.2019.04.002

12. Osteopontin-derived synthetic peptide SVVYGLR has potent utility in the functional regeneration of oral and maxillofacial skeletal muscles

Author:
Tanaka, Susumu; Matsushita, Yutaka; Hamada, Yoshinosuke; Kawaguchi, Naomasa; Usuki, Takasuke; Yokoyama, Yuhki; Tsuji, Tadataka; Yamamoto, Hirofumi; Kogo, Mikihiko
Source:
Peptides 2019 v.116 pp. 8-15
ISSN:
0196-9781
Subject:
skeletal muscle,   etc   ; animal models; electromyography; fibrosis; histopathology; muscles; surgery; synthetic peptides; tissue repair;     Show all 9 Subjects
Abstract:
... Oral and maxillofacial skeletal muscles are critical for oral motor functions, and severe damage to these muscles by trauma or surgery may lead to persistent functional impairment. This study investigated the effects of SVVYGLR (SV) peptide, a thrombin-cleaved osteopontin-derived motif, on histopathological wound healing and functional repair after severe injury of skeletal muscles. A rat model of ...
DOI:
10.1016/j.peptides.2019.04.013

13. Differential lethal and sublethal effects in embryonic zebrafish exposed to different sizes of silver nanoparticles

Author:
Liu, Xiaobo; Dumitrescu, Eduard; Kumar, Ajeet; Austin, Daniel; Goia, Dan; Wallace, Kenneth N.; Andreescu, Silvana
Source:
Environmental pollution 2019 v.248 pp. 627-634
ISSN:
0269-7491
Subject:
skeletal muscle,   etc   ; Danio rerio; cations; death; intestines; mortality; nanosilver; nitric oxide; salts; silver; sublethal effects;     Show all 11 Subjects
Abstract:
... Various parameters can influence the toxic response to silver nanoparticles (Ag NPs), including the size and surface properties, as well as the exposure environment and the biological site of action. Herein, we assess the intestinal toxicity of three different sizes (10, 40, and 100 nm) of Ag NPs in embryonic zebrafish, and describe the relationship between the properties and behavior of Ag NPs in ...
DOI:
10.1016/j.envpol.2019.02.085

14. Combined bead-based multiplex detection of RNA and protein biomarkers: Implications for understanding the time course of skeletal muscle injury and repair

Author:
Gary, Melody A.; Tanner, Elizabeth A.; Davis, Asheal A.; McFarlin, Brian K.
Source:
Methods 2019 v.158 pp. 92-96
ISSN:
1046-2023
Subject:
skeletal muscle,   etc   ; biomarkers; blood sampling; cytokine receptors; cytokines; exercise; messenger RNA; models; muscles; oxidative stress;     Show all 10 Subjects
Abstract:
... Biological response to skeletal muscle injury time course is generally classified as initial (elevated within first 4-h), delayed (elevated at 24-h), and/or prolonged (elevated at 4-h and sustained to 24-h). Accurate description of this process requires the ability to measure a robust set of RNA and protein biomarkers, yet such an approach is not common and not always feasible. This method propose ...
DOI:
10.1016/j.ymeth.2018.11.012

15. Combining single molecule counting with bead-based multiplexing to quantify biological inflammation time course following skeletal muscle injury

Author:
Tanner, Elizabeth A.; Gary, Melody A.; Davis, Asheal A.; McFarlin, Brian K.
Source:
Methods 2019 v.158 pp. 77-80
ISSN:
1046-2023
Subject:
skeletal muscle,   etc   ; exercise; inflammation; interleukin-1beta; interleukin-6; muscles; tumor necrosis factor-alpha;     Show all 7 Subjects
Abstract:
... Bead-based analysis methods allow for the exploration of a variety of complex biological processes. In particular, these techniques can be applied to better understand how peripheral muscle injury contributes to systemic inflammation. Understanding how these two processes affect one another can give additional insight concerning how changes in inflammation effect readiness to perform in exercise a ...
DOI:
10.1016/j.ymeth.2018.11.013

16. Development of a human skeletal micro muscle platform with pacing capabilities

Author:
Mills, Richard J.; Parker, Benjamin L.; Monnot, Pauline; Needham, Elise.J; Vivien, Celine J.; Ferguson, Charles; Parton, Robert G.; James, David E.; Porrello, Enzo R.; Hudson, James E.
Source:
Biomaterials 2019 v.198 pp. 217-227
ISSN:
0142-9612
Subject:
skeletal muscle,   etc   ; bioengineering; electrical treatment; exercise; humans; hypertrophy; muscles; myoblasts; optogenetics; proteins; screening; therapeutics;     Show all 12 Subjects
Abstract:
... Three dimensional engineered culture systems are powerful tools to rapidly expand our knowledge of human biology and identify novel therapeutic targets for disease. Bioengineered skeletal muscle has been recently shown to recapitulate many features of native muscle biology. However, current skeletal muscle bioengineering approaches require large numbers of cells, reagents and labour, limiting thei ...
DOI:
10.1016/j.biomaterials.2018.11.030

17. Different methods for diagnosis of sarcopenia and its association with nutritional status and survival in patients with advanced cancer in palliative care

Author:
da Silva, Jaqueline Rodrigues; Wiegert, Emanuelly Varea Maria; Oliveira, Livia; Calixto-Lima, Larissa
Source:
Nutrition 2019 v.60 pp. 48-52
ISSN:
0899-9007
Subject:
skeletal muscle,   etc   ; calf circumference; malnutrition; mortality; muscles; neoplasms; nutritional status; patients; prospective studies; regression analysis; sarcopenia;     Show all 11 Subjects
Abstract:
... The aim of the present study was to evaluate the association between sarcopenia, diagnosed by different muscle mass measurement techniques, with nutritional status and overall survival in patients with advanced cancer under palliative care.To investigate the association of sarcopenia, according to distinct muscle mass measurement methods, with nutritional status and overall survival (OS).This obse ...
DOI:
10.1016/j.nut.2018.09.003

18. Skeletal muscle excitation-metabolism coupling

Author:
Díaz-Vegas, Alexis; Eisner, Verónica; Jaimovich, Enrique
Source:
Archives of biochemistry and biophysics 2019 v.664 pp. 89-94
ISSN:
0003-9861
Subject:
skeletal muscle,   etc   ; adenosine triphosphate; calcium; electrical treatment; energy; homeostasis; mitochondria; muscle fibers; muscles; myofibrils; proteins;     Show all 11 Subjects
Abstract:
... Mitochondria represent the main source of ATP in skeletal muscle and mitochondria activity increases after muscle fiber depolarization. The regulation of mitochondrial function during contraction in skeletal muscle, however, is poorly understood.Skeletal muscle has a particular distribution of mitochondria where three distinct populations can be recognized. The most studied populations are the one ...
DOI:
10.1016/j.abb.2019.01.037

19. Enhancing the Work Capacity of Electrochemical Artificial Muscles by Coiling Plies of Twist-Released Carbon Nanotube Yarns

Author:
Kim, Keon Jung; Hyeon, Jae Sang; Kim, Hyunsoo; Mun, Tae Jin; Haines, Carter S.; Li, Na; Baughman, Ray H.; Kim, Seon Jeong
Source:
ACS applied materials & interfaces 2019 v.11 no.14 pp. 13533-13537
ISSN:
1944-8252
Subject:
skeletal muscle,   etc   ; air; capacitance; carbon nanotubes; electrochemistry; electrolytes; energy; exoskeleton; fabrics; mammals; muscles; sodium chloride; yarns;     Show all 13 Subjects
Abstract:
... Twisted-yarn-based artificial muscles can potentially be used in diverse applications, such as valves in microfluidic devices, smart textiles, air vehicles, and exoskeletons, because of their high torsional and tensile strokes, high work capacities, and long cycle life. Here, we demonstrate electrochemically powered, hierarchically twisted carbon nanotube yarn artificial muscles that have a contra ...
DOI:
10.1021/acsami.8b21417

20. Prognostic significance of sarcopenia and skeletal muscle mass change during preoperative chemoradiotherapy in locally advanced rectal cancer

Author:
Chung, Eric; Lee, Hye Sun; Cho, Eun-Suk; Park, Eun Jung; Baik, Seung Hyuk; Lee, Kang Young; Kang, Jeonghyun
Source:
Clinical nutrition 2019
ISSN:
0261-5614
Subject:
skeletal muscle,   etc   ; colorectal neoplasms; computed tomography; confidence interval; models; muscles; patents; patients; risk factors; sarcopenia;     Show all 10 Subjects
Abstract:
... The aim of this study was to investigate the prognostic impact of sarcopenia and skeletal muscle change in rectal cancer patients who underwent preoperative chemoradiotherapy (preop-CRT).From April 2004 to June 2013, we identified non-metastatic rectal cancer patients who underwent preop-CRT. Sarcopenia was evaluated according to previous cut-off value by computed tomography measured before starti ...
DOI:
10.1016/j.clnu.2019.03.014