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1. Physical exercise: An inducer of positive oxidative stress in skeletal muscle aging

Author:
Thirupathi, Anand; Pinho, Ricardo A.; Chang, Yan-Zhong
Source:
Life sciences 2020 v.252 pp. 117630
ISSN:
0024-3205
Subject:
skeletal muscle,   etc   ; exercise; homeostasis; oxidative stress;     Show all 4 Subjects
Abstract:
... Oxidative stress is the core of most pathological situations, and its attribution toward disease conversion is not yet well established. The adaptive capacity of a cell can overcome ROS-induced pathology. However, when a cell fails to extend its maximum adaptive capacity against oxidative stress, it could lead a cell to misbehave or defunct from its normal functions. Any type of physical activity ...
DOI:
10.1016/j.lfs.2020.117630

2. WITHDRAWN: Optimization of the rat digit abduction score (DAS) assay: Evaluation of botulinum neurotoxin activity in the gastrocnemius lateralis, peronei, and extensor digitorum longus

Author:
Cornet, Sylvie; Périer, Cindy; Kalinichev, Mikhail
Source:
Toxicon 2020
ISSN:
0041-0101
Subject:
skeletal muscle,   etc   ; botulinum toxin; rats; toxicity testing;     Show all 4 Subjects
Abstract:
... The Publisher regrets that this article is an accidental duplication of an article that has already been published, https://doi.org/10.1016/j.toxcx.2020.100029. The duplicate article has therefore been withdrawn.The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/our-business/policies/article-withdrawal ...
DOI:
10.1016/j.toxicon.2020.02.014

3. Computed tomography-based psoas skeletal muscle area and radiodensity are poor sentinels for whole L3 skeletal muscle values

Author:
Rollins, Katie E.; Gopinath, Aravin; Awwad, Amir; Macdonald, Ian A.; Lobo, Dileep N.
Source:
Clinical nutrition 2020 v.39 no.7 pp. 2227-2232
ISSN:
0261-5614
Subject:
skeletal muscle,   etc   ; computed tomography; computer software; muscles; patients; sarcopenia; Canada;     Show all 7 Subjects
Abstract:
... Computed tomography (CT)-based measurement of skeletal muscle cross-sectional area (CSA) and Hounsfield unit (HU) radiodensity are used to assess the presence of sarcopenia and myosteatosis, respectively. The validated CT-based technique involves analysis of skeletal muscle at the third lumbar vertebral (L3) level. Recently there has been increasing interest in the use of psoas muscle alone as a s ...
DOI:
10.1016/j.clnu.2019.10.003

4. Variability in skeletal muscle fibre characteristics during repeated muscle biopsy sampling in human vastus lateralis

Author:
Nederveen, Joshua P.; Ibrahim, George; Fortino, Stephen A.; Snijders, Tim; Kumbhare, Dinesh; Parise, Gianni
Source:
Applied physiology, nutrition and metabolism 2020 v.45 no.4 pp. 368-375
ISSN:
1715-5320
Subject:
skeletal muscle,   etc   ; biopsy; humans; men; metabolism; muscle fibers; muscles; nutrition;     Show all 8 Subjects
Abstract:
... The percutaneous muscle biopsy procedure is an invaluable tool for characterizing skeletal muscle and capillarization. Little is known about methodological or biological variation stemming from the technique in heterogeneous muscle. Five muscle biopsies were taken from the vastus lateralis of a group of young men (n = 29, 22 ± 1 years) over a 96-h period. We investigated the repeatability of fibre ...
DOI:
10.1139/apnm-2019-0263

5. Thermal stimulation at 39°C facilitates the fusion and elongation of C2C12 myoblasts

Author:
Hayashi, Satoko; Yonekura, Shinichi
Source:
Animal science journal = 2019 v.90 no.8 pp. 1008-1017
ISSN:
1344-3941
Subject:
skeletal muscle,   etc   ; antibodies; myoblasts; myotubes;     Show all 4 Subjects
Abstract:
... The aim of this study was to determine the effect of thermal stimulation at 39°C on the fusion and elongation of skeletal muscle cells. During a 5 day differentiation process of C2C12 cells, nine groups subjected to varying lengths of thermal stimulation at 39°C were established. Afterward, all groups were immunostained using anti‐muscle heavy‐chain antibody to test for myotube formation. Quantifi ...
DOI:
10.1111/asj.13227

6. Circ-HIPK3 plays an active role in regulating myoblast differentiation

Author:
Yao, Rui; Yao, Yang; Li, Cunyuan; Li, Xiaoyue; Ni, Wei; Quan, Renzhe; Liu, Li; Li, Huixiang; Xu, Yueren; Zhang, Mengdan; Ullah, Yaseen; Hu, Shengwei
Source:
International journal of biological macromolecules 2020 v.155 pp. 1432-1439
ISSN:
0141-8130
Subject:
skeletal muscle,   etc   ; bioinformatics; cell differentiation; developmental stages; luciferase; muscle development; muscles; myoblasts;     Show all 8 Subjects
Abstract:
... The development of skeletal muscle is a complex biological process involving a variety of regulatory pathways. A deeper understanding of the developmental mechanisms of skeletal muscle is of great significance for the treatment of muscular lesions. In recent years, studies have shown that circRNAs, as a new class of post-transcriptional regulators, play an important regulatory role in a variety of ...
DOI:
10.1016/j.ijbiomac.2019.11.119

7. Early high protein intake and mortality in critically ill ICU patients with low skeletal muscle area and -density

Author:
Looijaard, Wilhelmus G.P.M.; Dekker, Ingeborg M.; Beishuizen, Albertus; Girbes, Armand R.J.; Oudemans-van Straaten, Heleen M.; Weijs, Peter J.M.
Source:
Clinical nutrition 2020 v.39 no.7 pp. 2192-2201
ISSN:
0261-5614
Subject:
skeletal muscle,   etc   ; adults; computed tomography; databases; males; mortality; nutritional support; optimal nutrition; patients; protein intake; vertebrae;     Show all 11 Subjects
Abstract:
... Optimal nutritional support during the acute phase of critical illness remains controversial. We hypothesized that patients with low skeletal muscle area and -density may specifically benefit from early high protein intake. Aim of the present study was to determine the association between early protein intake (day 2–4) and mortality in critically ill intensive care unit (ICU) patients with normal ...
DOI:
10.1016/j.clnu.2019.09.007

8. Effect of cell-extracellular matrix interaction on myogenic characteristics and artificial skeletal muscle tissue

Author:
Ding, Ran; Horie, Masanobu; Nagasaka, Sumire; Ohsumi, Saki; Shimizu, Kazunori; Honda, Hiroyuki; Nagamori, Eiji; Fujita, Hideaki; Kawamoto, Takuo
Source:
Journal of bioscience and bioengineering 2020 v.130 no.1 pp. 98-105
ISSN:
1389-1723
Subject:
skeletal muscle,   etc   ; biological models; cell fusion; cell movement; extracellular matrix; integrins; mice; myoblasts; myotubes;     Show all 9 Subjects
Abstract:
... Although various types of artificial skeletal muscle tissue have been reported, the contractile forces generated by tissue-engineered artificial skeletal muscles remain to be improved for biological model and clinical applications. In this study, we investigated the effects of extracellular matrix (ECM) and supplementation of a small molecule, which has been reported to enhance α7β1 integrin expre ...
DOI:
10.1016/j.jbiosc.2020.02.008

9. Cleavage of FNDC5 and insights into its maturation process

Author:
Nie, Yongwei; Dai, Bai; Guo, Xudong; Liu, Dongjun
Source:
Molecular and cellular endocrinology 2020 v.510 pp. 110840
ISSN:
0303-7207
Subject:
skeletal muscle,   etc   ; adipose tissue; brain; endoplasmic reticulum; exercise; glycosylation; secretion; signal peptide;     Show all 8 Subjects
Abstract:
... FNDC5 corresponds to an irisin precursor that increases with exercise. Studies suggest that irisin mediates beneficial effects in adipose tissues, skeletal muscle, bone, and brain. However, the cleavage and maturation processes of FNDC5 have not been clearly identified. This study aimed to show that the signal peptide and transmembrane domain of FNDC5 were associated with the secretion of its ecto ...
DOI:
10.1016/j.mce.2020.110840

10. Preferential deficit of fat-free soft tissue in the appendicular region of children with cerebral palsy and proposed statistical models to capture the deficit

Author:
Zhang, Chuan; Colquitt, Gavin; Miller, Freeman; Shen, Ye; Modlesky, Christopher M.
Source:
Clinical nutrition 2020 v.39 no.5 pp. 1541-1550
ISSN:
0261-5614
Subject:
skeletal muscle,   etc   ; cerebral palsy; children; dual-energy X-ray absorptiometry; statistical models;     Show all 5 Subjects
Abstract:
... Cerebral palsy (CP) is a neurological disorder characterized by a profound skeletal muscle deficit. However, whether there is a regional-specific skeletal muscle deficit in children with CP is unknown. The purpose of this study was to determine whether fat-free soft tissue mass (FFST), a commonly used surrogate for skeletal muscle mass, is more compromised in the limbs than in the trunk in childre ...
DOI:
10.1016/j.clnu.2019.06.020

11. mTORC1-Mediated Satellite Cell Differentiation Is Required for Lysine-Induced Skeletal Muscle Growth

Author:
Jin, Cheng-long; Zhang, Zong-ming; Song, Zhi-wen; Gao, Chun-qi; Yan, Hui-chao; Wang, Xiu-qi
Source:
Journal of agricultural and food chemistry 2020 v.68 no.17 pp. 4884-4892
ISSN:
1520-5118
Subject:
skeletal muscle,   etc   ; cell differentiation; humans; longissimus muscle; lysine; myogenic regulatory factors; nutrition; protein synthesis; rapamycin;     Show all 9 Subjects
Abstract:
... Skeletal muscle is the primary source of protein for humans. However, the mechanisms of skeletal muscle growth, such as nutrition control, remain unknown. Moreover, the function of lysine (Lys) in controling skeletal muscle growth has gradually demonstrated that Lys is not only substantial for protein synthesis but also a signaling molecule for satellite cell (SC) activation. In the current work, ...
DOI:
10.1021/acs.jafc.0c01275

12. Skeletal muscle loss phenotype in cirrhosis: A nationwide analysis of hospitalized patients

Author:
Vural, Adil; Attaway, Amy; Welch, Nicole; Zein, Joe; Dasarathy, Srinivasan
Source:
Clinical nutrition 2020
ISSN:
0261-5614
Subject:
skeletal muscle,   etc   ; alcohols; databases; females; health care costs; hospitals; mortality; muscles; patients; phenotype; regression analysis;     Show all 11 Subjects
Abstract:
... There are very limited data on the healthcare burden of muscle loss, the most frequent complication in hospitalized cirrhotics. We determined the healthcare impact of a muscle loss phenotype in hospitalized cirrhotics.The Nationwide Inpatient Sample (NIS) database (years 2010–2014) was analyzed. Search terms included cirrhosis and its complications, and an expanded definition of a muscle loss phen ...
DOI:
10.1016/j.clnu.2020.03.032

13. Prognostic significance of sarcopenia and skeletal muscle mass change during preoperative chemoradiotherapy in locally advanced rectal cancer

Author:
Chung, Eric; Lee, Hye Sun; Cho, Eun-Suk; Park, Eun Jung; Baik, Seung Hyuk; Lee, Kang Young; Kang, Jeonghyun
Source:
Clinical nutrition 2020 v.39 no.3 pp. 820-828
ISSN:
0261-5614
Subject:
skeletal muscle,   etc   ; colorectal neoplasms; computed tomography; confidence interval; models; muscles; patents; patients; risk factors; sarcopenia;     Show all 10 Subjects
Abstract:
... The aim of this study was to investigate the prognostic impact of sarcopenia and skeletal muscle change in rectal cancer patients who underwent preoperative chemoradiotherapy (preop-CRT).From April 2004 to June 2013, we identified non-metastatic rectal cancer patients who underwent preop-CRT. Sarcopenia was evaluated according to previous cut-off value by computed tomography measured before starti ...
DOI:
10.1016/j.clnu.2019.03.014

14. Relationship of Peripheral Lymphocyte Subsets and Skeletal Muscle Mass Index in Sarcopenia: A Cross-Sectional Study

Author:
Huang, S.-W.; Xu, T.; Zhang, C.-T.; Zhou, Hong-Lian
Source:
The journal of nutrition, health & aging 2020 v.24 no.3 pp. 325-329
ISSN:
1279-7707
Subject:
skeletal muscle,   etc   ; T-lymphocytes; body composition; cross-sectional studies; gerontology; hospitals; muscles; pathogenesis; patients; sarcopenia; China;     Show all 11 Subjects
Abstract:
... OBJECTIVES: Lymphocytes can affect the proliferation and migration of muscle satellite cells, which may be associated with reduced muscle mass in patients with sarcopenia. The present study aimed to further enrich understandings of the changes of blood lymphocytes and explore the relationship between peripheral lymphocyte subsets and muscle mass in patients with sarcopenia. DESIGN: A cross-section ...
DOI:
10.1007/s12603-020-1329-0

15. Combined intake of astaxanthin, β-carotene, and resveratrol elevates protein synthesis during muscle hypertrophy in mice

Author:
Kawamura, Aki; Aoi, Wataru; Abe, Ryo; Kobayashi, Yukiko; Wada, Sayori; Kuwahata, Masashi; Higashi, Akane
Source:
Nutrition 2020 v.69 pp. 110561
ISSN:
0899-9007
Subject:
skeletal muscle,   etc   ; antioxidants; astaxanthin; beta-carotene; diet; hypertrophy; mice; muscles; muscular atrophy; phosphorylation; protein synthesis; resveratrol;     Show all 12 Subjects
Abstract:
... The antioxidant factors, astaxanthin, β-carotene, and resveratrol, have a potential effect on protein synthesis in skeletal muscle and a combined intake may have a greater cumulative effect than individual intake. The aim of this study was to investigate the combined effects on skeletal muscle mass and protein metabolic signaling during the hypertrophic process from atrophy in mice.Male ICR mice w ...
DOI:
10.1016/j.nut.2019.110561

16. The Effect of Yearly-Dose Vitamin D Supplementation on Muscle Function in Mice

Author:
Hayes, Alan; Rybalka, Emma; Debruin, Danielle A.; Hanson, Erik D.; Scott, David; Sanders, Kerrie
Source:
Nutrients 2019 v.11 no.5
ISSN:
2072-6643
Subject:
skeletal muscle,   etc   ; hindlimbs; mice; muscles; vitamin D;     Show all 5 Subjects
Abstract:
... Supplementation with vitamin D helps to alleviate weakness and fatigue seen with deficiency. However, large bolus doses appear to worsen the risk of falls. Whether this occurs as a direct result of muscle weakness is currently unknown. Thus, the aims of this study were to examine the muscle function following administration of high doses of vitamin D. Given the safety issues associated with bolus ...
DOI:
10.3390/nu11051097
PubMed:
31108908
PubMed Central:
PMC6566598

17. Correction: Hydrogel microfibers with perfusable folded channels for tissue constructs with folded morphology

Author:
Liu, Yupeng; Xu, Peidi; Liang, Zhe; Xie, Ruoxiao; Ding, Mingyu; Liu, Hongxia; Liang, Qionglin
Source:
RSC advances 2019 v.9 no.19 pp. 10625
ISSN:
2046-2069
Subject:
skeletal muscle,   etc   ; endoderm; hydrogels; intestines; tissue engineering;     Show all 5 Subjects
Abstract:
... Correction for ‘Hydrogel microfibers with perfusable folded channels for tissue constructs with folded morphology’ by Yupeng Liu et al., RSC Adv., 2018, 8, 23475–23480. ...
DOI:
10.1039/c9ra90025j

18. Physiological Parameters of Bream (Abramis brama L.) in Parts of the Rybinsk Reservoir of Different Types

Author:
Payuta, A. A.; Pryanichnikova, E. G.; Shcherbina, G. Kh.; Perova, S. N.; Flerova, E. A.
Source:
Inland water biology 2019 v.12 no.2 pp. 217-224
ISSN:
1995-0829
Subject:
skeletal muscle,   etc   ; Abramis brama; bream; forage; pollution;     Show all 5 Subjects
Abstract:
... The specific features of accumulation of fat, protein, mineral, and nitrogen-free extractive substances in the skeletal muscles of bream (Abramis brama L.) from areas of the Rybinsk reservoir subjected to different degrees of anthropogenic load have been studied. Data on the bream forage base and feeding in the reservoir are presented. It is shown that, in the areas of the Sheksninskii Reach with ...
DOI:
10.1134/S1995082919020123

19. Preoperative abnormal body composition is closely related to bacteremia after living donor liver transplantation

Author:
Kamo, Naoko; Kaido, Toshimi; Miyachi, Yosuke; Iwamura, Sena; Yao, Siyuan; Shirai, Hisaya; Yagi, Shintaro; Uemoto, Shinji
Source:
Nutrition 2020 v.77 pp. 110798
ISSN:
0899-9007
Subject:
skeletal muscle,   etc   ; adipose tissue; antibiotics; bacteremia; body composition; computed tomography; death; liver transplant; multivariate analysis; patients; risk factors; survival rate;     Show all 12 Subjects
Abstract:
... Infection is the most critical cause of early death after liver transplantation (LT). However, the effect of preoperative body composition on bacteremia after LT is unclear. The aim of this study was to examine the effects of preoperative body composition on bacteremia after living donor LT (LDLT).The study comprised 277 patients who underwent LDLT at Kyoto University, Kyoto, Japan, between Januar ...
DOI:
10.1016/j.nut.2020.110798

20. NDUFS4 deletion triggers loss of NDUFA12 in Ndufs4−/− mice and Leigh syndrome patients: A stabilizing role for NDUFAF2

Author:
Adjobo-Hermans, Merel J.W.; de Haas, Ria; Willems, Peter H.G.M.; Wojtala, Aleksandra; van Emst-de Vries, Sjenet E.; Wagenaars, Jori A.; van den Brand, Mariel; Rodenburg, Richard J.; Smeitink, Jan A.M.; Nijtmans, Leo G.; Sazanov, Leonid A.; Wieckowski, Mariusz R.; Koopman, Werner J.H.
Source:
Biochimica et biophysica acta 2020 v.1861 no.8 pp. 148213
ISSN:
0005-2728
Subject:
skeletal muscle,   etc   ; brain; computer simulation; death; diaphragm; fibroblasts; genes; heart; kidneys; lipids; liver; mice; mitochondria; mutation; oxidative phosphorylation; patients; proteome;     Show all 17 Subjects
Abstract:
... Mutations in NDUFS4, which encodes an accessory subunit of mitochondrial oxidative phosphorylation (OXPHOS) complex I (CI), induce Leigh syndrome (LS). LS is a poorly understood pediatric disorder featuring brain-specific anomalies and early death. To study the LS pathomechanism, we here compared OXPHOS proteomes between various Ndufs4⁻/⁻ mouse tissues. Ndufs4⁻/⁻ animals displayed significantly lo ...
DOI:
10.1016/j.bbabio.2020.148213