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1. Ethnopharmacology, phytochemistry, pharmacology, clinical applications and toxicology of the genus Stellera Linn.: A review

Author:
Zhang, Nuan; He, Jun; Xia, Cong-Yuan; Lian, Wen-Wen; Yan, Yu; Ding, Kang; Zhang, Ya-Yao; Xu, Jie-Kun; Zhang, Wei-Ku
Source:
Journal of ethnopharmacology 2021 v.264 pp. 112915
ISSN:
0378-8741
Subject:
skin diseases,   etc   ; Internet; Stellera chamaejasme; chemical composition; coumarins; databases; flavonoids; flora; herbs; lignans; medicinal properties; neoplasms; pain; roots; shrubs; temperate zones; terpenoids; therapeutics; toxicity; toxicology; traditional medicine; China; West Asia;     Show all 23 Subjects
Abstract:
... The genus Stellera Linn. consists of species of perennial herbs and shrubs, and is mainly distributed in the temperate regions of east Asia to west Asia. There are 10∼12 species in the world, two species in China: Stellera chamaejasme Linn. and Stellera formosana Hayata ex Li. As recorded, the roots of Stellera species are used to dissipate phlegm and relieve pain. The roots and the barks can be u ...
DOI:
10.1016/j.jep.2020.112915

2. Macroscopic, biochemical and hystological evaluation of topical anti-inflammatory activity of Casearia sylvestris (Flacourtiaceae) in mice

Author:
Heymanns, Ana Caroline; Albano, Micheline N.; da Silveira, Márcia R.; Muller, Simony D.; Petronilho, Fabrícia C.; Gainski, Lucinéia D.; Cargnin-Ferreira, Eduardo; Piovezan, Anna P.
Source:
Journal of ethnopharmacology 2021 v.264 pp. 113139
ISSN:
0378-8741
Subject:
skin diseases,   etc   ; Casearia sylvestris; Croton; anti-inflammatory activity; dexamethasone; dual-energy X-ray absorptiometry; ears; edema; enzyme activity; euthanasia; laboratory animals; males; mast cells; mice; models; morphometry; myeloperoxidase; nitrates; nitrites; oils; traditional medicine; Brazil;     Show all 22 Subjects
Abstract:
... Inflammatory skin diseases presents high prevalence and lack of alternatives that can be used for self-care by the population. Casearia sylvestris is a plant used topically in different communities in Brazil, to treat wounds or promote cutaneous healing. To evaluate the topical anti-inflammatory activity for the crude hydroalcoholic extract of Casearia sylvestris (HCE-CS) in the models of single o ...
DOI:
10.1016/j.jep.2020.113139

3. Prediction of Skin Disease Using Ensemble Data Mining Techniques and Feature Selection Method—a Comparative Study

Author:
Verma, Anurag Kumar; Pal, Saurabh; Kumar, Surjeet
Source:
Applied biochemistry and biotechnology 2020 v.190 no.2 pp. 341-359
ISSN:
0273-2289
Subject:
skin diseases,   etc   ; algorithms; artificial intelligence; comparative study; data collection; prediction;     Show all 6 Subjects
Abstract:
... Nowadays, skin disease is a major problem among peoples worldwide. Different machine learning techniques are applied to predict the various classes of skin disease. In this research paper, we have applied six different machine learning algorithm to categorize different classes of skin disease using three ensemble techniques and then a feature selection method to compare the results obtained from d ...
DOI:
10.1007/s12010-019-03093-z

4. Anti-inflammatory activity of ethyl acetate and n-butanol extracts from Ranunculus macrophyllus Desf. and their phenolic profile

Author:
Deghima, Amirouche; Righi, Nadjat; Rosales-Conrado, Noelia; León-González, María Eugenia; Baali, Faiza; Gómez-Mejía, Esther; Madrid, Yolanda; Bedjou, Fatiha
Source:
Journal of ethnopharmacology 2021 v.265 pp. 113347
ISSN:
0378-8741
Subject:
skin diseases,   etc   ; 2,2-diphenyl-1-picrylhydrazyl; Ranunculus; acute toxicity; anti-inflammatory activity; antioxidant activity; beta-carotene; bleaching; butanol; chromatography; ears; ethyl acetate; hesperidin; inflammation; inhibitory concentration 50; kaempferol; linoleic acid; medicinal plants; myricetin; peroxidation; plant extracts; rutin; traditional medicine; triterpenoids; xylene; Algeria;     Show all 26 Subjects
Abstract:
... The members of the genus Ranunculus have counter-irritating properties and thus, they are traditionally used for treating anti-inflammatory disorders and other skin conditions. Ranunculus macrophyllus Desf. is a wild medicinal plant growing in Algeria and traditionally used to treat some cutaneous skin disorders.The aim of this study was to characterize the composition of the ethyl acetate and n-b ...
DOI:
10.1016/j.jep.2020.113347

5. Foam in pharmaceutical and medical applications

Author:
Parsa, Maryam; Trybala, Anna; Malik, Danish Javed; Starov, Victor
Source:
Current opinion in colloid & interface science 2019 v.44 pp. 153-167
ISSN:
1359-0294
Subject:
skin diseases,   etc   ; compliance; foams; patients;     Show all 4 Subjects
Abstract:
... Topical foams are an attractive and promising delivery system for cosmetic, pharmaceutical and medical applications due to their beneficial properties, ease of application and enhanced patients’ acceptability/compliance. Below the recent developments of topical foams for cosmetic and dermal applications are reviewed, classification based on foam formulation is provided and recent assessment method ...
DOI:
10.1016/j.cocis.2019.10.007

6. Molecular detection and phylogenetic analysis of lumpy skin disease virus from outbreaks in Uganda 2017–2018

Author:
Ochwo, Sylvester; VanderWaal, Kimberly; Ndekezi, Christian; Nkamwesiga, Joseph; Munsey, Anna; Witto, Sarah Gift; Nantima, Noelina; Mayanja, Franklin; Okurut, Anna Rose Ademun; Atuhaire, David Kalenzi; Mwiine, Frank Norbert
Source:
BMC veterinary research 2020 v.16 no.1 pp. 66
ISSN:
1746-6148
Subject:
Lumpy skin disease virus; lumpy skin disease,   etc   ; G-protein coupled receptors; biopsy; blood sampling; cattle; genes; molecular epidemiology; nucleic acids; phylogeny; sequence diversity; vaccines; Eurasia; Europe; Uganda;     Show all 15 Subjects
Abstract:
... BACKGROUND: Lumpy skin disease (LSD) is an infectious viral disease of cattle caused by a Capripoxvirus. LSD has substantial economic implications, with infection resulting in permanent damage to the skin of affected animals which lowers their commercial value. In Uganda, LSD is endemic and cases of the disease are frequently reported to government authorities. This study was undertaken to molecul ...
DOI:
10.1186/s12917-020-02288-5
PubMed:
32085763
PubMed Central:
PMC7035724

7. Inferences about the transmission of lumpy skin disease virus between herds from outbreaks in Albania in 2016

Author:
Gubbins, Simon; Stegeman, Arjan; Klement, Eyal; Pite, Ledi; Broglia, Alessandro; Cortiñas Abrahantes, José
Source:
Preventive veterinary medicine 2020 v.181 pp. 104602
ISSN:
0167-5877
Subject:
Lumpy skin disease virus; lumpy skin disease,   etc   ; Stomoxys calcitrans; cattle; hematophagous insects; herds; mathematical models; probability; seasonal variation; temperature; vaccination; vaccines; virus transmission; Africa; Albania; Balkans; Greece;     Show all 17 Subjects
Abstract:
... Lumpy skin disease has recently emerged as a major threat to cattle populations outside of Africa, where it is endemic. In 2015 the first ever European outbreaks occurred in Greece, which were followed by spread across much of the Balkans in 2016. Here we use a simple mathematical model for the transmission of lumpy skin disease virus (LSDV) between herds to explore factors influencing its spread ...
DOI:
10.1016/j.prevetmed.2018.12.008

8. Lumpy Skin Disease Is Characterized by Severe Multifocal Dermatitis With Necrotizing Fibrinoid Vasculitis Following Experimental Infection

Author:
Sanz-Bernardo, Beatriz; Haga, Ismar R.; Wijesiriwardana, Najith; Hawes, Philippa C.; Simpson, Jennifer; Morrison, Linda R.; MacIntyre, Neil; Brocchi, Emiliana; Atkinson, John; Haegeman, Andy; De Clercq, Kris; Darpel, Karin E.; Beard, Philippa M.
Source:
Veterinary pathology 2020 v.57 no.3 pp. 388-396
ISSN:
1544-2217
Subject:
Lumpy skin disease virus; lumpy skin disease,   etc   ; animal pathology; calves; caregivers; dermatitis; dermis; edema; fibroblasts; histiocytes; immunohistochemistry; inclusion bodies; inflammation; keratinocytes; necrosis; vasculitis; Africa; Asia; Europe;     Show all 19 Subjects
Abstract:
... Lumpy skin disease is a high-consequence disease in cattle caused by infection with the poxvirus lumpy skin disease virus (LSDV). The virus is endemic in most countries in Africa and an emerging threat to cattle populations in Europe and Asia. As LSDV spreads into new regions, it is important that signs of disease are recognized promptly by animal caregivers. This study describes the gross, micros ...
DOI:
10.1177/0300985820913268
PubMed:
32314676
PubMed Central:
PMC7201124

9. Removal of bovine viral diarrhea virus (BVDV) from lumpy skin disease virus (LSDV) vaccine stocks by passage on chorioallantoic membranes of fertilized hens’ eggs

Author:
Munyanduki, Henry; Omar, Ruzaiq; Douglass, Nicola; Williamson, Anna-Lise
Source:
Journal of virological methods 2020 v.275 pp. 113752
ISSN:
0166-0934
Subject:
Lumpy skin disease virus; skin diseases,   etc   ; Bovine viral diarrhea virus 1; animal pathogens; cattle; eggs; fetal bovine serum; hens; kidneys; testes; vaccines;     Show all 11 Subjects
Abstract:
... Bovine viral diarrhea virus (BVDV) is a common contaminant of Madin-Darby bovine kidney (MDBK) cells as well as fetal calf serum (FCS). It is pathogenic to cattle and regulatory authorities require that veterinary vaccine stocks are free from BVDV. MDBK cells are used in the generation of recombinant lumpy skin disease virus (LSDV) and have been used for the growth of LSDV vaccines. This paper des ...
DOI:
10.1016/j.jviromet.2019.113752

10. Cutaneous Filariasis in Free-Ranging Rothschild's Giraffes (Giraffa camelopardalis rothschildi) in Uganda

Author:
Whittier, Christopher A.; Murray, Suzan; Holder, Kali; McGraw, Sabrina; Fleischer, Robert; Cortes-Rodriguez, Nandadevi; Black, Peter; Yordi, Robert; Keigwin, Michael; Enyel, Eric; Atimnedi, Patrick
Source:
Journal of wildlife diseases 2020 v.56 no.1 pp. 234-238
ISSN:
0090-3558
Subject:
skin diseases,   etc   ; Giraffa camelopardalis; etiology; filariasis; infectious diseases; parasites; risk assessment; Uganda;     Show all 8 Subjects
Abstract:
... Across Africa, wild giraffes suffer from a variety of skin disorders of mostly unknown etiology. With their populations already threatened from anthropogenic factors, it is important to understand infectious disease risks to giraffes. Here we describe filarid parasites and a portion of their genetic sequence associated with skin disease in Rothschild's giraffes (Giraffa camelopardalis rothschildi) ...
DOI:
10.7589/2018-09-212

11. Methods for extraction and ex-vivo experimentation with the most complex human commensal, Demodex spp.

Author:
Clanner-Engelshofen, Benjamin M.; French, Lars E.; Reinholz, Markus
Source:
Experimental & applied acarology 2020 v.80 no.1 pp. 59-70
ISSN:
0168-8162
Subject:
skin diseases,   etc   ; Demodex; acarology; ectoparasites; exoskeleton; fluorescent dyes; freezing; humans; microbiome; mites; skin (animal);     Show all 11 Subjects
Abstract:
... Demodex spp. mites are the most complex organisms of the human skin microbiome and were discovered more than 175 years ago, yet only little basic research is published about them. As they can be pathophysiologically relevant ectoparasites associated with rosacea, pityriasis folliculorum, and other inflammatory skin diseases, more research should be encouraged. Being a large microorganism or a tiny ...
DOI:
10.1007/s10493-019-00450-9

12. Post-Kala-Azar Dermal Leishmaniasis as a Reservoir for Visceral Leishmaniasis Transmission

Author:
Le Rutte, Epke A.; Zijlstra, Eduard E.; de Vlas, Sake J.
Source:
Trends in parasitology 2019 v.35 no.8 pp. 590-592
ISSN:
1471-4922
Subject:
skin diseases,   etc   ; models; visceral leishmaniasis; xenodiagnosis; India;     Show all 5 Subjects
Abstract:
... Post-kala-azar dermal leishmaniasis (PKDL) is a parasitic skin infection which can occur after visceral leishmaniasis (VL). Recent xenodiagnosis studies (Mondal et al., Clin. Infect. Dis., 2018) have uncovered the infectiousness of PKDL. When including this in a transmission model, PKDL cases appear as an important reservoir of infection, likely frustrating the VL elimination efforts on the Indian ...
DOI:
10.1016/j.pt.2019.06.007
PubMed:
31266711
PubMed Central:
PMC6667731

13. The KEAP1/NRF2 Signaling Pathway in Keratinization

Author:
Ishitsuka, Yosuke; Ogawa, Tatsuya; Roop, Dennis
Source:
Antioxidants 2020 v.9 no.8
ISSN:
2076-3921
Subject:
skin diseases,   etc   ; animal models; epithelium; genes; genotype-environment interaction; insulating materials; integument; keratinization; metabolism; mice; mutation; phenotype; signal transduction; sulfur;     Show all 14 Subjects
Abstract:
... Keratinization is a tissue adaptation, but aberrant keratinization is associated with skin disorders such as ichthyoses, atopic dermatitis, psoriasis, and acne. The disease phenotype stems from the interaction between genes and the environment; therefore, an understanding of the adaptation machinery may lead to a new appreciation of pathomechanisms. The KEAP1/NRF2 signaling pathway mediates the en ...
DOI:
10.3390/antiox9080751

14. Overview of diagnostic tools for Capripox virus infections

Author:
Haegeman, Andy; De Vleeschauwer, Annebel; De Leeuw, Ilse; Vidanović, Dejan; Šekler, Milanko; Petrović, Tamaš; Demarez, Céline; Lefebvre, David; De Clercq, Kris
Source:
Preventive veterinary medicine 2020 v.181 pp. 104704
ISSN:
0167-5877
Subject:
lumpy skin disease,   etc   ; Goatpox virus; Sheeppox virus; cattle; diagnostic techniques; goats; monitoring; sheep; sheep pox; vaccines; viruses;     Show all 11 Subjects
Abstract:
... Capripox viruses are the causative agents of important animal diseases in cattle (Lumpy Skin Disease), sheep (Sheeppox) and goats (Goatpox) with severe socio-economic impact in case of wide scale outbreaks. Therefore there is a constant need for adequate diagnostic tools. The assays must be fit-for-purpose to identify the virus quickly and correctly and to be useful for surveillance and monitoring ...
DOI:
10.1016/j.prevetmed.2019.104704

15. Antioxidative photochemoprotector effects of cerium oxide nanoparticles on UVB irradiated fibroblast cells

Author:
Peloi, Karen E.; Contreras Lancheros, César A.; Nakamura, Celso V.; Singh, Sushant; Neal, Craig; Sakthivel, Tamil S.; Seal, Sudpita; Lautenschlager, Suelide Oliveira Silva
Source:
Colloids and surfaces 2020 v.191 pp. 111013
ISSN:
0927-7765
Subject:
skin diseases,   etc   ; antioxidant activity; antioxidant enzymes; catalase; enzyme activity; fibroblasts; irradiation; nanoceria; reactive oxygen species; superoxide dismutase; ultraviolet radiation;     Show all 11 Subjects
Abstract:
... The Ultraviolet-B radiation (UVB) might induce cellular redox imbalance which plays an important role in the development of skin disorders. Thus, the search for photochemoprotective alternatives with antioxidant efficacy would be a safe aspect towards prevention of skin diseases. Cerium oxide nanoparticles (CNPs) have antioxidant properties, that are mostly related to CNPs catalase and superoxide ...
DOI:
10.1016/j.colsurfb.2020.111013

16. Goatpox virus (G20-LKV) vaccine strain elicits a protective response in cattle against lumpy skin disease at challenge with lumpy skin disease virulent field strain in a comparative study

Author:
Zhugunissov, K.; Bulatov, Ye.; Orynbayev, M.; Kutumbetov, L.; Abduraimov, Ye.; Shayakhmetov, Ye.; Taranov, D.; Amanova, Zh; Mambetaliyev, M.; Absatova, Zh.; Azanbekova, M.; Khairullin, B.; Zakarya, K.; Tuppurainen, E.
Source:
Veterinary microbiology 2020 v.245 pp. 108695
ISSN:
0378-1135
Subject:
lumpy skin disease,   etc   ; Goatpox virus; antibodies; cattle; comparative study; fever; mice; rabbits; seroconversion; skin lesions; vaccines; virulence;     Show all 12 Subjects
Abstract:
... In this comparative study, we examine the safety of the sheeppox (SPP) and goatpox (GTP) vaccines and the protective response of these vaccines in cattle against a virulent lumpy skin disease (LSD) field strain. The vaccine safety was tested in rabbits, mice and cattle using ten times recommended dose. In the safety trial, none of the vaccinated animals showed any deviation from physiological norm ...
DOI:
10.1016/j.vetmic.2020.108695

17. Target lipidomics approach to reveal the resolution of inflammation induced by Chinese medicine combination in Liu-Shen-Wan against realgar overexposure to rats

Author:
Wang, Jiaojiao; Ding, Lanfang; Zhou, Jing; Ma, Hongyue; Wu, Yuanyuan; Wang, Jiajia; Lv, Xiang; Liu, Shengjin; Wang, Hengbin; Yan, Yanqing; Luo, Niancui; Li, Quan; Xu, Huiqin; Di, Liuqing; Wu, Qinan; Duan, Jinao
Source:
Journal of ethnopharmacology 2020 v.249 pp. 112171
ISSN:
0378-8741
Subject:
skin diseases,   etc   ; Oriental traditional medicine; arsenic; drugs; eicosanoids; inflammation; liver; oral administration; overdose; rats; respiratory system; risk; sulfides; toxicity; Asia;     Show all 15 Subjects
Abstract:
... Liu-Shen-Wan (LSW) is one of the popular over-the-counter drugs in Asia, which contains realgar (As₄S₄), used for the treatment of upper respiratory tract inflammation and skin infections. However, the safety and potential risk of this arsenic remain unknown.The aim of this study was to determine total arsenic in tissue and investigate effects of regular dose and overdose LSW exposure on rat liver ...
DOI:
10.1016/j.jep.2019.112171

18. Efficacy of topically administered fluralaner or imidacloprid/moxidectin on dogs with generalised demodicosis

Author:
Fourie, Josephus J.; Meyer, Leon; Thomas, Emmanuel
Source:
Parasites & vectors 2019 v.12 no.1 pp. 59
ISSN:
1756-3305
Subject:
skin diseases,   etc   ; Demodex; dogs; moxidectin; mites; imidacloprid; topical application; demodicosis;     Show all 8 Subjects
Abstract:
... BACKGROUND: Canine demodicosis is classified as localised or generalised according to the extent of the disease. Chronic generalised demodicosis is a difficult skin disease to treat and unlikely to resolve without therapy. This laboratory study compared the efficacy of two topical spot-on medications, fluralaner or a combination of imidacloprid and moxidectin, against naturally acquired generalise ...
DOI:
10.1186/s13071-018-3230-9
PubMed:
30683143
PubMed Central:
PMC6346496

19. Compromising human skin in vivo and ex vivo to study skin barrier repair

Author:
Berkers, T.; Boiten, W.A.; Absalah, S.; van Smeden, J.; Lavrijsen, A.P.M.; Bouwstra, J.A.
Source:
Biochimica et biophysica acta 2019 v.1864 no.8 pp. 1103-1108
ISSN:
1388-1981
Subject:
skin diseases,   etc   ; ceramides; humans; lipid composition; models; skin (animal);     Show all 6 Subjects
Abstract:
... Ex vivo regenerated stratum corneum (SC) after tape-stripping can be used as a model to study the barrier function of compromised skin. Yet, details about how close the regenerated SC model mimics the lipid properties (e.g. lipid composition and lipid ordering) of the in vivo situation are not known. Here, we examined using a comprehensive ceramide analysis whether human ex vivo regenerated SC sho ...
DOI:
10.1016/j.bbalip.2019.04.005

20. Advice on assistance and protection provided by the Scientific Advisory Board of the Organisation for the Prohibition of Chemical Weapons: Part 1. On medical care and treatment of injuries from nerve agents

Author:
Timperley, Christopher M.; Forman, Jonathan E.; Abdollahi, Mohammad; Al-Amri, Abdullah Saeed; Baulig, Augustin; Benachour, Djafer; Borrett, Veronica; Cariño, Flerida A.; Geist, Michael; Gonzalez, David; Kane, William; Kovarik, Zrinka; Martínez-Álvarez, Roberto; Mourão, Nicia Maria Fusaro; Neffe, Slawomir; Raza, Syed K.; Rubaylo, Valentin; Suárez, Alejandra Graciela; Takeuchi, Koji; Tang, Cheng; Trifirò, Ferruccio; van Straten, Francois Mauritz; Vanninen, Paula S.; Vučinić, Slavica; Zaitsev, Volodymyr; Zafar-Uz-Zaman, Muhammad; Zina, Mongia Saïd; Holen, Stian
Source:
Toxicology 2019 v.415 pp. 56-69
ISSN:
0300-483X
Subject:
skin diseases,   etc   ; health care workers; humans; nerve agents; neurotoxicity; therapeutics;     Show all 6 Subjects
Abstract:
... The Scientific Advisory Board (SAB) of the Organisation for the Prohibition of Chemical Weapons (OPCW) has provided advice on assistance and protection in relation to the Chemical Weapons Convention. In this, the first of several papers describing the SAB’s work on this topic, we describe advice given in response to questions from the OPCW Director-General in 2013 and 2014 on the status of availab ...
DOI:
10.1016/j.tox.2019.01.004