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1. Post-Kala-Azar Dermal Leishmaniasis as a Reservoir for Visceral Leishmaniasis Transmission

Author:
Le Rutte, Epke A.; Zijlstra, Eduard E.; de Vlas, Sake J.
Source:
Trends in parasitology 2019 v.35 no.8 pp. 590-592
ISSN:
1471-4922
Subject:
skin diseases,   etc   ; models; visceral leishmaniasis; xenodiagnosis; India;     Show all 5 Subjects
Abstract:
... Post-kala-azar dermal leishmaniasis (PKDL) is a parasitic skin infection which can occur after visceral leishmaniasis (VL). Recent xenodiagnosis studies (Mondal et al., Clin. Infect. Dis., 2018) have uncovered the infectiousness of PKDL. When including this in a transmission model, PKDL cases appear as an important reservoir of infection, likely frustrating the VL elimination efforts on the Indian ...
DOI:
10.1016/j.pt.2019.06.007

2. Compromising human skin in vivo and ex vivo to study skin barrier repair

Author:
Berkers, T.; Boiten, W.A.; Absalah, S.; van Smeden, J.; Lavrijsen, A.P.M.; Bouwstra, J.A.
Source:
Biochimica et biophysica acta 2019 v.1864 no.8 pp. 1103-1108
ISSN:
1388-1981
Subject:
skin diseases,   etc   ; ceramides; humans; lipid composition; models; skin (animal);     Show all 6 Subjects
Abstract:
... Ex vivo regenerated stratum corneum (SC) after tape-stripping can be used as a model to study the barrier function of compromised skin. Yet, details about how close the regenerated SC model mimics the lipid properties (e.g. lipid composition and lipid ordering) of the in vivo situation are not known. Here, we examined using a comprehensive ceramide analysis whether human ex vivo regenerated SC sho ...
DOI:
10.1016/j.bbalip.2019.04.005

3. Advice on assistance and protection provided by the Scientific Advisory Board of the Organisation for the Prohibition of Chemical Weapons: Part 1. On medical care and treatment of injuries from nerve agents

Author:
Timperley, Christopher M.; Forman, Jonathan E.; Abdollahi, Mohammad; Al-Amri, Abdullah Saeed; Baulig, Augustin; Benachour, Djafer; Borrett, Veronica; Cariño, Flerida A.; Geist, Michael; Gonzalez, David; Kane, William; Kovarik, Zrinka; Martínez-Álvarez, Roberto; Mourão, Nicia Maria Fusaro; Neffe, Slawomir; Raza, Syed K.; Rubaylo, Valentin; Suárez, Alejandra Graciela; Takeuchi, Koji; Tang, Cheng; Trifirò, Ferruccio; van Straten, Francois Mauritz; Vanninen, Paula S.; Vučinić, Slavica; Zaitsev, Volodymyr; Zafar-Uz-Zaman, Muhammad; Zina, Mongia Saïd; Holen, Stian
Source:
Toxicology 2019 v.415 pp. 56-69
ISSN:
0300-483X
Subject:
skin diseases,   etc   ; health care workers; humans; nerve agents; neurotoxicity; therapeutics;     Show all 6 Subjects
Abstract:
... The Scientific Advisory Board (SAB) of the Organisation for the Prohibition of Chemical Weapons (OPCW) has provided advice on assistance and protection in relation to the Chemical Weapons Convention. In this, the first of several papers describing the SAB’s work on this topic, we describe advice given in response to questions from the OPCW Director-General in 2013 and 2014 on the status of availab ...
DOI:
10.1016/j.tox.2019.01.004

4. Auto-immune skin diseases in animals: time to reclassify and review after 40 years

Author:
Olivry, Thierry
Source:
BMC veterinary research 2018 v.14 no.1 pp. 157
ISSN:
1746-6148
Subject:
skin diseases,   etc   ; cats; dogs; histology; veterinary medicine;     Show all 5 Subjects
Abstract:
... It has been more than 40 years since the dual descriptions of canine pemphigus vulgaris. Over the ensuing four decades, the reports of—mostly canine—novel autoimmune skin diseases (AISDs) have progressed in successive waves separated by long periods of quiescence. This Editorial introduces a series of comprehensive review papers on the various canine and feline AISDs. This collection of articles a ...
DOI:
10.1186/s12917-018-1477-1
PubMed:
29751810
PubMed Central:
PMC5948701

5. Construction of recombinant capripoxviruses as vaccine vectors for delivering foreign antigens: Methodology and application

Author:
Liu, Fuxiao; Zhang, Hongliang; Liu, Wenhua
Source:
Comparative immunology, microbiology, and infectious diseases 2019 v.65 pp. 181-188
ISSN:
0147-9571
Subject:
Lumpy skin disease virus; lumpy skin disease,   etc   ; Goatpox virus; Sheeppox virus; antigens; cattle; disease severity; homologous recombination; live vaccines; recombinant vaccines; sheep; signs and symptoms (animals and humans);     Show all 12 Subjects
Abstract:
... Goatpox (GTP), sheeppox (SPP) and lumpy skin disease (LSD) are three severe diseases of goat, sheep and cattle. Their typical clinical symptoms are characterized by vesicles, papules, nodules, pustules and scabs on animal skins. The GTP, SPP and LSD are caused by goatpox virus (GTPV), sheeppox virus (SPPV) and lumpy skin disease virus (LSDV), respectively, all of which belong to the genus Capripox ...
DOI:
10.1016/j.cimid.2019.05.013

6. Detection of antibodies against Lumpy skin disease virus by Virus neutralization test and ELISA methods

Author:
Samojlović, Milena; Polaček, Vladimir; Gurjanov, Vladimir; Lupulović, Diana; Lazić, Gospava; Petrović, Tamaš; Lazić, Sava
Source:
Acta veterinaria 2019 v.69 no.1 pp. 47-60
ISSN:
1820-7448
Subject:
Lumpy skin disease virus; lumpy skin disease,   etc   ; antibodies; cell lines; cows; diagnostic techniques; enzyme-linked immunosorbent assay; financial economics; herds; kidneys; livestock production; neutralization tests; vaccination; Serbia;     Show all 14 Subjects
Abstract:
... Infection of cattle with lumpy skin disease virus (LSDV) is very important from the aspect of livestock production. Although it can cause significant economic losses, available serological assays are still not sufficiently efficient and reliable. A 3-day VNT was performed using Madin-Darby bovine kidney (MDBK) cell line and LSDV isolated from clinically infected cow to improve serological diagnost ...
DOI:
10.2478/acve-2019-0003

7. Efficacy of topically administered fluralaner or imidacloprid/moxidectin on dogs with generalised demodicosis

Author:
Fourie, Josephus J.; Meyer, Leon; Thomas, Emmanuel
Source:
Parasites & vectors 2019 v.12 no.1 pp. 59
ISSN:
1756-3305
Subject:
skin diseases,   etc   ; Demodex; demodicosis; dogs; imidacloprid; mites; moxidectin; therapeutics; topical application;     Show all 9 Subjects
Abstract:
... BACKGROUND: Canine demodicosis is classified as localised or generalised according to the extent of the disease. Chronic generalised demodicosis is a difficult skin disease to treat and unlikely to resolve without therapy. This laboratory study compared the efficacy of two topical spot-on medications, fluralaner or a combination of imidacloprid and moxidectin, against naturally acquired generalise ...
DOI:
10.1186/s13071-018-3230-9

8. Cell-penetrating peptide: a means of breaking through the physiological barriers of different tissues and organs

Author:
Xu, Jiangkang; Khan, Abdur Rauf; Fu, Manfei; Wang, Rujuan; Ji, Jianbo; Zhai, Guangxi
Source:
Journal of controlled release 2019 v.309 pp. 106-124
ISSN:
0168-3659
Subject:
skin diseases,   etc   ; cell membranes; drug therapy; inflammation; models; myocardial ischemia; neoplasms; nerve tissue; peptides;     Show all 9 Subjects
Abstract:
... The selective infiltration of cell membranes and tissue barriers often blocks the entry of most active molecules. This natural defense mechanism prevents the invasion of exogenous substances and limits the therapeutic value of most available molecules. Therefore, it is particularly important to find appropriate ways of membrane translocation and therapeutic agent delivery to its target site. Cell ...
DOI:
10.1016/j.jconrel.2019.07.020

9. Furan inhibitory activity against tyrosinase and impact on B16F10 cell toxicity

Author:
Barros, Marcela Rodrigues; Menezes, Thaís Meira; da Silva, Lucas Pereira; Pires, Dartagnam Sá; Princival, Jefferson Luiz; Seabra, Gustavo; Neves, Jorge Luiz
Source:
International journal of biological macromolecules 2019 v.136 pp. 1034-1041
ISSN:
0141-8130
Subject:
skin diseases,   etc   ; cytotoxicity; enzyme activity; enzyme inhibition; enzyme inhibitors; enzymes; furans; melanoma; mushrooms; spectroscopy; viability;     Show all 11 Subjects
Abstract:
... Many skin disorders and diseases are related to tyrosinase activity, in particular, due to the vital role played by this enzyme in the melanogenic process. Although numerous natural and synthetic tyrosinase inhibitors have been published, substantial efforts have been made to understand the influence of tyrosinase inhibition on the viability of melanoma cells. Here, we assess the impact of two ket ...
DOI:
10.1016/j.ijbiomac.2019.06.120

10. Effect of blue light irradiation on the stability of phospholipid molecules in the presence of epigallocatechin-3-gallate

Author:
Pires, Filipa; Geraldo, Vananelia P.N.; Antunes, Andrea; Marletta, Alexandre; Oliveira, Osvaldo N.; Raposo, Maria
Source:
Colloids and surfaces 2019 v.177 pp. 50-57
ISSN:
0927-7765
Subject:
skin diseases,   etc   ; blue light; colloids; epigallocatechin gallate; green tea; hydrophobicity; irradiation; phospholipids; photosensitivity; sodium; spectroscopy; therapeutics;     Show all 12 Subjects
Abstract:
... In this paper, we report on the effects from epigallocatechin-3-gallate (EGCG), a phytochemical flavonoid present in green tea, on Langmuir monolayers of 1,2-dipalmitoyl-sn-glycero-3-[phospho-rac-(1-glycerol) (sodium salt) (DPPG), including experiments with blue light irradiation. EGCG was found to interact with both the DPPG headgroups and hydrophobic tails, thus affecting the lipid packing accor ...
DOI:
10.1016/j.colsurfb.2019.01.042

11. FADD-deficient mouse embryonic fibroblasts undergo RIPK1-dependent apoptosis and autophagy after NB-UVB irradiation

Author:
Antunovic, Maja; Matic, Igor; Nagy, Biserka; Caput Mihalic, Katarina; Skelin, Josipa; Stambuk, Jerko; Josipovic, Pavle; Dzinic, Tamara; Paradzik, Mladen; Marijanovic, Inga
Source:
Journal of photochemistry and photobiology 2019 v.194 pp. 32-45
ISSN:
1011-1344
Subject:
skin diseases,   etc   ; apoptosis; autophagy; cell viability; death; fibroblasts; irradiation; mice; necroptosis; proteins; ultraviolet radiation;     Show all 11 Subjects
Abstract:
... Sun or therapy-related ultraviolet B (UVB) irradiation induces different cell death modalities such as apoptosis, necrosis/necroptosis and autophagy. Understanding of mechanisms implicated in regulation and execution of cell death program is imperative for prevention and treatment of skin diseases. An essential component of death-inducing complex is Fas-associated protein with death domain (FADD), ...
DOI:
10.1016/j.jphotobiol.2019.03.007

12. Hydrogel scaffold with substrate elasticity mimicking physiological-niche promotes proliferation of functional keratinocytes

Author:
Mogha, Pankaj; Srivastava, Ankita; Kumar, Sushant; Das, Sreya; Kureel, Sanjay; Dwivedi, Alka; Karulkar, Atharva; Jain, Nikita; Sawant, Abhijeet; Nayak, Chitra; Majumder, Abhijit; Purwar, Rahul
Source:
RSC advances 2019 v.9 no.18 pp. 10174-10183
ISSN:
2046-2069
Subject:
skin diseases,   etc   ; chemokine CXCL10; drugs; gene therapy; gene transfer; genes; humans; hydrogels; keratinocytes; patients; tissue culture;     Show all 11 Subjects
Abstract:
... High numbers of autologous human primary keratinocytes (HPKs) are required for patients with burns, wounds and for gene therapy of skin disorders. Although freshly isolated HPKs exhibit a robust regenerative capacity, traditional methodology fails to provide a sufficient number of cells. Here we demonstrated a well characterized, non-cytotoxic and inert hydrogel as a substrate that mimics skin ela ...
DOI:
10.1039/c9ra00781d

13. Cracking and fracture properties of potato (Solanum tuberosum L.) tubers and their relation to dry matter, starch, and mineral distribution

Author:
Koch, Mirjam; Naumann, Marcel; Pawelzik, Elke
Source:
Journal of the science of food and agriculture 2019 v.99 no.6 pp. 3149-3156
ISSN:
0022-5142
Subject:
skin diseases,   etc   ; Solanum tuberosum; calcium; cations; cell walls; cracking; magnesium; polymers; potatoes; rheological properties; starch; tubers;     Show all 12 Subjects
Abstract:
... BACKGROUND: Potato disorders lead to a significant reduction in the yield and quality of marketable tubers. Thumbnail cracks are physiological tuber skin disorders that can significantly affect the tuber's appearance and, hence, the overall quality. The aim of this study was to characterize fracture properties of the tuber skin. Knowledge of the physiological reasons that influence the resistance ...
DOI:
10.1002/jsfa.9530

14. Caregiver burden in the veterinary dermatology client: comparison to healthy controls and relationship to quality of life

Author:
Spitznagel, Mary Beth; Solc, Meghan; Chapman, Kimberly R.; Updegraff, John; Albers, Angela L.; Carlson, Mark D.
Source:
Veterinary dermatology 2019 v.30 no.1 pp. 3
ISSN:
0959-4493
Subject:
skin diseases,   etc   ; animal diseases; caregivers; disease control; dogs; pet ownership; pets; quality of life; veterinary medicine;     Show all 9 Subjects
Abstract:
... BACKGROUND: Skin disease in companion animals often requires long‐term management which may contribute to caregiver burden in the dermatology client. HYPOTHESES/OBJECTIVES: We expected greater caregiver burden in dermatology clients relative to healthy control veterinary clients and that no difference would be present between healthy controls and dermatology clients reporting good skin disease con ...
DOI:
10.1111/vde.12696

15. Insights into the role of endoplasmic reticulum stress in skin function and associated diseases

Author:
Park, Kyungho; Lee, Sang Eun; Shin, Kyong‐Oh; Uchida, Yoshikazu
Source:
TheFEBS journal 2019 v.286 no.2 pp. 413-425
ISSN:
1742-464X
Subject:
skin diseases,   etc   ; apoptosis; endoplasmic reticulum; endoplasmic reticulum stress; irradiation; melanoma; pathogenesis; proteins; unfolded protein response;     Show all 9 Subjects
Abstract:
... Endoplasmic reticulum (ER) stress is a mechanism that allows the protection of normal cellular functions in response to both internal perturbations, such as accumulation of unfolded proteins, and external perturbations, for example redox stress, UVB irradiation, and infection. A hallmark of ER stress is the accumulation of misfolded and unfolded proteins. Physiological levels of ER stress trigger ...
DOI:
10.1111/febs.14739

16. Isolation of Talaromyces marneffei from the Skin of an Egyptian Mongoose (Herpestes ichneumon) in Portugal

Author:
Matos, Ana C.; Alves, Daniela; Saraiva, Sofia; Soares, Ana S.; Soriano, Tatiana; Figueira, Luis; Fraga, Fátima; Matos, Manuela; Coelho, Ana C.
Source:
Journal of wildlife diseases 2019 v.55 no.1 pp. 238-241
ISSN:
0090-3558
Subject:
skin diseases,   etc   ; Herpestes; Talaromyces; fungi; polymerase chain reaction; wildlife diseases; Portugal;     Show all 7 Subjects
Abstract:
... We report a case of Talaromyces marneffei skin infection in an Egyptian mongoose (Herpestes ichneumon) in Portugal. The isolated fungus was identified through its mycologic characteristics, morphology, and PCR amplification. ...
DOI:
10.7589/2017-02-037

17. Humoral immune response to repeated lumpy skin disease virus vaccination and performance of serological tests

Author:
Milovanović, Milovan; Dietze, Klaas; Milićević, Vesna; Radojičić, Sonja; Valčić, Miroslav; Moritz, Tom; Hoffmann, Bernd
Source:
BMC veterinary research 2019 v.15 no.1 pp. 80
ISSN:
1746-6148
Subject:
Lumpy skin disease virus; skin diseases,   etc   ; adverse effects; antibodies; antibody detection; antigens; calves; calving; cows; enzyme-linked immunosorbent assay; farms; humoral immunity; injection site; mothers; neonates; seroprevalence; vaccination; Serbia;     Show all 18 Subjects
Abstract:
... BACKGROUND: In the presented study we investigated the development of the humoral immune response against LSDV during the process of re-vaccination of cattle over a time span of 5 months. In addition, the performance of different serological techniques for antibody detection against LSDV was compared. For sample collection, an area without previous LSD outbreak reports in Serbia was selected. Seve ...
DOI:
10.1186/s12917-019-1831-y

18. Seroprevalence and risk factors for lumpy skin disease virus seropositivity in cattle in Uganda

Author:
Ochwo, Sylvester; VanderWaal, Kimberly; Munsey, Anna; Nkamwesiga, Joseph; Ndekezi, Christian; Auma, Elda; Mwiine, Frank N.
Source:
BMC veterinary research 2019 v.15 no.1 pp. 236
ISSN:
1746-6148
Subject:
Lumpy skin disease virus; lumpy skin disease,   etc   ; antibodies; buffaloes; cattle; cross-sectional studies; drinking; enzyme-linked immunosorbent assay; farms; females; herd size; rain; regression analysis; risk factors; seroprevalence; wildlife; Uganda;     Show all 17 Subjects
Abstract:
... BACKGROUND: Lumpy skin disease (LSD) is a transboundary cattle disease caused by a Capripoxvirus of the family Poxviridae. In Uganda, documented information on the epidemiology of the disease is rare and there is no nationwide control plan, yet LSD is endemic. This study set out to investigate the seroprevalence of lumpy skin disease and determine the risk factors for LSD seropositivity, by carryi ...
DOI:
10.1186/s12917-019-1983-9

19. Transmission of lumpy skin disease virus: A short review

Author:
Sprygin, A.; Pestova, Ya; Wallace, D.B.; Tuppurainen, E.; Kononov, A.V.
Source:
Virus research 2019 v.269 pp. 197637
ISSN:
0168-1702
Subject:
Lumpy skin disease virus; lumpy skin disease,   etc   ; Aedes aegypti; Amblyomma; Musca domestica; Rhipicephalus; Stomoxys calcitrans; buffaloes; cattle; disease transmission; hematophagous arthropods; risk factors; seasonal variation; synanthropes; vaccination; viruses; Africa; Balkans; Caucasus region; Russia;     Show all 20 Subjects
Abstract:
... Lumpy skin disease (LSD) is a viral transboundary disease endemic throughout Africa and of high economic importance that affects cattle and domestic water buffaloes. Since 2012, the disease has spread rapidly and widely throughout the Middle Eastern and Balkan regions, southern Caucasus and parts of the Russian Federation. Before vaccination campaigns took their full effect, the disease continued ...
DOI:
10.1016/j.virusres.2019.05.015

20. Effect of using frozen–thawed bovine semen contaminated with lumpy skin disease virus on in vitro embryo production

Author:
Annandale, Cornelius Henry; Smuts, Mario P.; Ebersohn, Karen; du Plessis, Lizette; Thompson, Peter N.; Venter, Estelle H.; Stout, Tom A. E.
Source:
Transboundary and emerging diseases 2019 v.66 no.4 pp. 1539-1547
ISSN:
1865-1674
Subject:
Lumpy skin disease virus; lumpy skin disease,   etc   ; DNA; animal ovaries; blastocyst; bulls; cows; electron microscopy; embryo transfer; fever; freeze-thaw cycles; in vitro fertilization; oocytes; pneumonia; polymerase chain reaction; risk; semen; udders; virion; viruses; washing;     Show all 21 Subjects
Abstract:
... Lumpy skin disease (LSD) is an important transboundary animal disease of cattle with significant economic impact because of the implications for international trade in live animals and animal products. LSD is caused by a Capripoxvirus, LSD virus (LSDV), and results in extensive hide and udder damage, fever and pneumonia. LSDV can be shed in semen of infected bulls for prolonged periods and transmi ...
DOI:
10.1111/tbed.13179